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    Education

    IS PHARMACOLOGY DIFFICULT®️ Podcast

    Welcome all to “Is Pharmacology Difficult®️ podcast “. This is a Pharmacology podcast !! I am your host, Dr Radhika Vijay, M.B.B.S., M.D. Pharmacology, Sardar Patel Medical College, Bikaner, Rajasthan, India. Pharmacology (medical sciences) is my subject and I think Communicating about it to the masses is very essential. It is of great value and importance to every layman. The episodes here will be in simple English language (with few phrases and add ons of my favourite french language). The basic motto is to create an awareness and impart knowledge of the subject to all interested, concerned, curious and visitors. Pharmacology, the “SCIENCE OF DRUGS”, which hold an important place in everyone’s life. Here, I will discuss basic tips, strategies and ideas to study medical pharmacology easily and effectively especially for medical, nursing, dental and pharmacy schools and students. Even if you are not from Science stream, this information would be beneficial to you and therefore pay some valuable minutes to this Pharmacology Podcast, and you will not be in loss !! The descriptions will be short pieces of science work lengthy enough to engage you and not to test your patience! So, go ahead, lend your ears to these crispy informative audio files and empower and enrich your sea of knowledge and let me know “IS PHARMACOLOGY DIFFICULT?” For various links, please visit: https://linktr.ee/ispharmacologydifficult. Disclaimer: All the content of the podcast audio is expressed in my own language and learning and understanding viewpoints. References are from the best and reputed subject (Pharmacology) text books, blogs, journals and drug information from reputed and best online sources. I make best efforts to convey the most accurate and updated information of the subject of medical sciences in my special way. I take no money from pharmaceutical industry or drug companies for my podcast. You are most welcome to post your comments, suggestions, etc. through “Contact” page on my website: www.ispharmacologydifficult.com. You all are well known that medical sciences subjects are ever changing, updated and ever evolving, hence no guarantee is taken if the information conveyed in this podcast turns outdated or obsolete with changing and evolving times. This podcast is an expression of my learnings and experiences and in no way representative of any standard authority. Privacy Notice: I collect only email addresses of the subscribers and in no circumstances they will be shared or displayed anywhere on podcast/website/newsletter. Copyright & Distribution: All the contents of “IS PHARMACOLOGY DIFFICULT®️” podcast/website/blog/newsletter are copyrighted. Though all the content related to podcast and various social media handles is free! “BUT” in no way or under no circumstances shall- Any of the podcast content/show notes/blog post/newsletter content/youtube video artwork/podcast artwork and ideas should be used or reproduced or distributed.

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    Latest Episodes:
    Is Pharmacology Difficult Podcast ROUTES OF DRUG ELIMINATION-4 Jun 13, 2021
    Show notes

    Would love to know your opinions & expectations -Dr Radhika Vijay

    Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay.
    In today's episode, I know the essence of French Open Tournament, wishing your favourite player the bestest of luck and wishes, if I am interrupting the score commentary, I do apologise, and promising a laconic set of colloque for the great Sunday, I break the ice with left over pizza pieces, i mean conversation about renal routes of drug elimination, in that too specifically , I will limit my talks to one process i.e. tubular secretion. I will discuss the mechanism, process, drug transporters, site, carriers, important facts, notable points, good gracious examples and everything you need to know about the process of Tubular Secretion.
    With the terse talk for Sunday, I advice you to carry on watching the score and keep the end excitement "ON" till you finally see the trophy in either Stefanos Tsitsipas' or Novak Djocovic's hand!Its truly a thrilling weekend!
    For all the updates and latest episodes of my podcast, please visit www.ispharmacologydifficult.com where you can also sign up for a free monthly newsletter of mine. It actually contains lot of updates about the medical sciences, drug information and my podcast updates also.
    You can follow me on different social media handles like twitter, insta, facebook and linkedin. They all are with same name "IS PHARMACOLOGY DIFFICULT". If you are listening for the first time, do follow me here, whatever platform you are consuming this episode, stay tuned, do rate and review on ITunes, Apple podcasts, stay safe, stay happy, stay enlightened, Thank you!!

    You can access various links via

    https://linktr.ee/ispharmacologydifficult

    • Please leave Review on Apple podcasts!
    • My E-Newsletter sign up at Substack!
    • Connect on Twitter & Instagram!
    • My books on Amazon & Goodreads!

    Is Pharmacology Difficult Podcast ROUTES OF DRUG ELIMINATION-3 Jun 10, 2021
    Show notes

    Would love to know your opinions & expectations -Dr Radhika Vijay

    Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay.
    I will be starting today's episode with a beautiful thought compilation about "Lantern" and the book "Sky Lantern" by Matt Makeloto, its a lovely contemplation!
    Then i will cover the start of last route of Drug Elimination for our list and it is the Renal Excretion. Its the interplay and mathematics of three key processes namely Glomerular filtration, Tubular reabsorption and Tubular Secretion.
    For the bright today, I will be covering details, factors, mechanism, process, examples and all about Glomerular filtration and Tubular reabsorption. Rest of the episode's strings gonna reverb in next episode. Till then Chau.....
    For all the updates and latest episodes of my podcast, please visit www.ispharmacologydifficult.com where you can also sign up for a free monthly newsletter of mine. It actually contains lot of updates about the medical sciences, drug information and my podcast updates also.
    You can follow me on different social media handles like twitter, insta, facebook and linkedin. They all are with same name "IS PHARMACOLOGY DIFFICULT". If you are listening for the first time, do follow me here, whatever platform you are consuming this episode, stay tuned, do rate and review on ITunes, Apple podcasts, stay safe, stay happy, stay enlightened, Thank you!!

    You can access various links via

    https://linktr.ee/ispharmacologydifficult

    • Please leave Review on Apple podcasts!
    • My E-Newsletter sign up at Substack!
    • Connect on Twitter & Instagram!
    • My books on Amazon & Goodreads!

    Is Pharmacology Difficult Podcast DRUG DOSAGES Jun 06, 2021
    Show notes

    Would love to know your opinions & expectations -Dr Radhika Vijay

    Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay.
    In today's bonus episode, i will be covering a true bonus value topic about Drug dosage, there are 5 types that I will talk about, namely 1. Fixed Dose 2. Variable dose (with crude adjustments) 3. Variable dose (with fine adjustments) 4. Maximum tolerated dose 5. Minimum tolerated Dose. Describing the essence of a bonus episode on Bonus Sunday, do l et me what it means for you? With a short lived bonus episode, I will be wrapping up today's truly bonus valuable convo, hope you felt the same way. Did you?
    For all the updates and latest episodes of my podcast, please visit www.ispharmacologydifficult.com where you can also sign up for a free monthly newsletter of mine. It actually contains lot of updates about the medical sciences, drug information and my podcast updates also.
    You can follow me on different social media handles like twitter, insta, facebook and linkedin. They all are with same name "IS PHARMACOLOGY DIFFICULT". If you are listening for the first time, do follow me here, whatever platform you are consuming this episode, stay tuned, do rate and review on ITunes, Apple podcasts, stay safe, stay happy, stay enlightened, Thank you!!

    You can access various links via

    https://linktr.ee/ispharmacologydifficult

    • Please leave Review on Apple podcasts!
    • My E-Newsletter sign up at Substack!
    • Connect on Twitter & Instagram!
    • My books on Amazon & Goodreads!

    Is Pharmacology Difficult Podcast ROUTES OF DRUG ELIMINATION-2 Jun 05, 2021
    Show notes

    Would love to know your opinions & expectations -Dr Radhika Vijay

    Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay.
    In today's episode I will talk about the whole details, mechanics and essence of Elimination of drugs in breast milk. Why this knowledge is important? is the first question answered. Then I will discuss some physiological rules, mechanism of action governing it, all the processes involved and much more....
    Next I will give few examples, explain the much involved Ion trapping mechanism, etc
    I will be covering a list of Drugs involved in breast feeding, almost all groups or groups of drugs will be covered, it will be thoroughly explained upto what extent, mild, moderate or severe does the drug has side effects, whether its safe or unsafe!
    With all this bag off loaded information and data, I will punch the ending of the episode with my glimpses about road turns adorned with beautiful quotes by Hellen Keller, etc
    Hope you all liked it!
    For all the updates and latest episodes of my podcast, please visit www.ispharmacologydifficult.com where you can also sign up for a free monthly newsletter of mine. It actually contains lot of updates about the medical sciences, drug information and my podcast updates also.
    You can follow me on different social media handles like twitter, insta, facebook and linkedin. They all are with same name "IS PHARMACOLOGY DIFFICULT". If you are listening for the first time, do follow me here, whatever platform you are consuming this episode, stay tuned, do rate and review on ITunes, Apple podcasts, stay safe, stay happy, stay enlightened, Thank you!!
    You can access various links via.-- https://linktr.ee/ispharmacologydifficult

    • Please leave Review on Apple podcasts!
    • My E-Newsletter sign up at Substack!
    • Connect on Twitter & Instagram!
    • My books on Amazon & Goodreads!

    Is Pharmacology Difficult Podcast ROUTES OF DRUG ELIMINATION-1 Jun 02, 2021
    Show notes

    Would love to know your opinions & expectations -Dr Radhika Vijay

    Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay.
    Live your life by a compass not by a clock, with this mantra, I will break the ice for today's episode, always try to be a compass, not an anchor, not a ship! With a compass, you will realise that all those who wander are not lost!!
    Today's education compass points towards Various routes of Drug Elimination and while I continue the untold part further, today's first head of talk is Feacal elimination, I will discuss in detail and will tell you about the mechanism, examples all in all!
    Next head of discussion is about Pulmonary/Alveolar Elimination. Its ideal for Volatile liquid drugs, Gaseous drugs and I will be giving you some nice examples, a little mechanism and medico legal importance via breathalysis!
    Lastly a few of the not very important routes to cover are Sweat, Saliva, Skin and Hair etc. I will give examples for each of these, Lastly a little contemplation and jest about Compass to teach you all to laugh uproariously at your own jest Sometimes, Someday!!
    For all the updates and latest episodes of my podcast, please visit www.ispharmacologydifficult.com where you can also sign up for a free monthly newsletter of mine. It actually contains lot of updates about the medical sciences, drug information and my podcast updates also.
    You can follow me on different social media handles like twitter, insta, facebook and linkedin. They all are with same name "IS PHARMACOLOGY DIFFICULT". If you are listening for the first time, do follow me here, whatever platform you are consuming this episode, stay tuned, do rate and review on ITunes, Apple podcasts, stay safe, stay happy, stay enlightened, Thank you!!

    You can access various links via

    https://linktr.ee/ispharmacologydifficult

    • Please leave Review on Apple podcasts!
    • My E-Newsletter sign up at Substack!
    • Connect on Twitter & Instagram!
    • My books on Amazon & Goodreads!

    Is Pharmacology Difficult Podcast DRUG ELIMINATION KINETICS INTRODUCTION May 31, 2021
    Show notes

    Would love to know your opinions & expectations -Dr Radhika Vijay

    Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay.
    In today's episode, I will answer your question , the one centred around topic of the day-"How drugs are eliminated?"Then I will tell you the difference in terms Excretion and Elimination. I will then start off the talk with discussions about Presystemic metabolism or First pass metabolism. After deriving an equation about Hepatic Extraction Ratio, I will officially start my talks about topic of the day i.e. Introduction to Kinetics of drug elimination. I will be listing various major and minor routes of drug elimination, then I will be initially give full description of Biliary excretion.In this I will be laying special emphasis upon "Enterohepatic Cycling". Definition, essence, examples, features, mechanism, exceptions , all will be conveyed and explained nicely! I will be concluding today's talks with two phrases or words of wisdom, science and mathematics to solve day to day dilemmas ! To wrap up, until next time(A' la prochaine!).....
    For all the updates and latest episodes of my podcast, please visit www.ispharmacologydifficult.com where you can also sign up for a free monthly newsletter of mine. It actually contains lot of updates about the medical sciences, drug information and my podcast updates also.
    You can follow me on different social media handles like twitter, insta, facebook and linkedin. They all are with same name "IS PHARMACOLOGY DIFFICULT". If you are listening for the first time, do follow me here, whatever platform you are consuming this episode, stay tuned, do rate and review on ITunes, Apple podcasts, stay safe, stay happy, stay enlightened, Thank you!!

    You can access various links via

    https://linktr.ee/ispharmacologydifficult

    • Please leave Review on Apple podcasts!
    • My E-Newsletter sign up at Substack!
    • Connect on Twitter & Instagram!
    • My books on Amazon & Goodreads!

    Is Pharmacology Difficult Podcast FACTORS AFFECTING BIOTRANSFORMATION OF DRUGS May 27, 2021
    Show notes

    Would love to know your opinions & expectations -Dr Radhika Vijay

    Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay.
    Let us be quite very truly, genuinely be thoughtful, in deepest mindset very thankful to lord for the blessings countable and easily experienced as cool showers amongst hot humid weathers!
    The trendy topic for a thankful Thursday is knowledge of factors affecting drug metabolism or drug biotransformation. The most important ones are age, genetic variations, diet, food, nutrition components , drug interactions and pathological states.
    While not much of great importance are the factors like sex, race, species etc. though I have given examples of animal models for these too, but primarily keep the above points in mind as they form the pillar factors causing sea changes in biotransformation or metabolism for lot many drugs! With this set of factors, we officially finish the discussions about drug metabolism or drug biotransformation and our jet plane heads while soaring high in sky towards the last pillar of pharmacokinetics i.e. Drug Elimination, Wow! the News is that from next episode we gonna begin Kinetics of Drug Elimination!!
    For all the updates and latest episodes of my podcast, please visit www.ispharmacologydifficult.com where you can also sign up for a free monthly newsletter of mine. It actually contains lot of updates about the medical sciences, drug information and my podcast updates also.
    You can follow me on different social media handles like twitter, insta, facebook and linkedin. They all are with same name "IS PHARMACOLOGY DIFFICULT". If you are listening for the first time, do follow me here, whatever platform you are consuming this episode, stay tuned, do rate and review on ITunes, Apple podcasts, stay safe, stay happy, stay enlightened, Thank you!!

    You can access various links via

    https://linktr.ee/ispharmacologydifficult

    • Please leave Review on Apple podcasts!
    • My E-Newsletter sign up at Substack!
    • Connect on Twitter & Instagram!
    • My books on Amazon & Goodreads!

    Is Pharmacology Difficult Podcast ENZYME INDUCTION & ENZYME INHIBITION May 23, 2021
    Show notes

    Would love to know your opinions & expectations -Dr Radhika Vijay

    Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay.
    In today's episode I will talk about definition, important details, clinical relevance and apt examples regarding both enzyme induction and enzyme inhibition. Though a little lengthy episode but no regrets for action, its only meant for inaction!!
    For all the updates and latest episodes of my podcast, please visit www.ispharmacologydifficult.com where you can also sign up for a free monthly newsletter of mine. It actually contains lot of updates about the medical sciences, drug information and my podcast updates also.
    You can follow me on different social media handles like twitter, insta, facebook and linkedin. They all are with same name "IS PHARMACOLOGY DIFFICULT". If you are listening for the first time, do follow me here, whatever platform you are consuming this episode, stay tuned, do rate and review on ITunes, Apple podcasts, stay safe, stay happy, stay enlightened, Thank you!!

    You can access various links via

    https://linktr.ee/ispharmacologydifficult

    • Please leave Review on Apple podcasts!
    • My E-Newsletter sign up at Substack!
    • Connect on Twitter & Instagram!
    • My books on Amazon & Goodreads!

    Is Pharmacology Difficult Podcast PHARMACOKINETICS-PHASES OF DRUG REACTIONS May 20, 2021
    Show notes

    Would love to know your opinions & expectations -Dr Radhika Vijay

    Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay.
    In today's episode, my advice to be expanded all throughout today's tell tales is "Follow the river and you will reach the sea". Yes to embrace the immensity, vastness of sea, you need to follow the particular mannerism and fashion of a task consistently in order to experience the completion and sufficiency.
    With this thread in our hand, lets start spinning up the introduction to our episode, it starts with Phase 1 reaction, which further branches in oxidation, reduction and hydrolysis reactions and then they have their own subtypes and yes examples too!!
    Next comes the Phase 2 reactions, in these I will narrate the essence of Conjugation, Acetylation and much many minor metabolic pathways and yes their subtypes and examples too!!
    All the reactions will be discussed in sufficient details and lastly I will be giving a signature talk about Hofmann reaction or better to understand non enzymatic reactions!!
    With these utmost important discussions, time strikes the moment to call it for the day and end the soaring fun ride in this sea, hope you all experiences the vastness of waters and dived in to achieve complacency!!
    For all the updates and latest episodes of my podcast, please visit www.ispharmacologydifficult.com where you can also sign up for a free monthly newsletter of mine. It actually contains lot of updates about the medical sciences, drug information and my podcast updates also.
    You can follow me on different social media handles like twitter, insta, facebook and linkedin. They all are with same name "IS PHARMACOLOGY DIFFICULT". If you are listening for the first time, do follow me here, whatever platform you are consuming this episode, stay tuned, do rate and review on ITunes, Apple podcasts, stay safe, stay happy, stay enlightened, Thank you!!

    You can access various links via

    https://linktr.ee/ispharmacologydifficult

    • Please leave Review on Apple podcasts!
    • My E-Newsletter sign up at Substack!
    • Connect on Twitter & Instagram!
    • My books on Amazon & Goodreads!

    Is Pharmacology Difficult Podcast DRUG METABOLISING ENZYMES-1 May 18, 2021
    Show notes

    Would love to know your opinions & expectations -Dr Radhika Vijay

    Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay.
    Wonder is the beginning of wisdom!! I'd rather open my mind with wonder than close it with belief!! That's the mantra for today as I start the topic of day which goes on like "Drug Metabolising Enzymes-1"
    I will start my convo by classifying metabolising enzymes into Microsomal and Non microsomal. Then I will throw light on each of the characteristics, features, sub heads and examples of each type, their details though not in much depth will be conversed upon!!
    i will in detail cover variety of isoenzymes of superfamily cytochrome P450, their different isoenzymes, features, inducers, inhibitors, etc.
    I will be talking in detail about nomenclature, specificity and genetic variability.
    That is the time and moment not to give in or give up, rather listen to clock's command to call it for the day and pack it all in!
    For all the updates and latest episodes of my podcast, please visit www.ispharmacologydifficult.com where you can also sign up for a free monthly newsletter of mine. It actually contains lot of updates about the medical sciences, drug information and my podcast updates also.
    You can follow me on different social media handles like twitter, insta, facebook and linkedin. They all are with same name "IS PHARMACOLOGY DIFFICULT". If you are listening for the first time, do follow me here, whatever platform you are consuming this episode, stay tuned, do rate and review on ITunes, Apple podcasts, stay safe, stay happy, stay enlightened, Thank you!!

    You can access various links via

    https://linktr.ee/ispharmacologydifficult

    • Please leave Review on Apple podcasts!
    • My E-Newsletter sign up at Substack!
    • Connect on Twitter & Instagram!
    • My books on Amazon & Goodreads!

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