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    Education

    IS PHARMACOLOGY DIFFICULT®️ Podcast

    Welcome all to “Is Pharmacology Difficult®️ podcast “. This is a Pharmacology podcast !! I am your host, Dr Radhika Vijay, M.B.B.S., M.D. Pharmacology, Sardar Patel Medical College, Bikaner, Rajasthan, India. Pharmacology (medical sciences) is my subject and I think Communicating about it to the masses is very essential. It is of great value and importance to every layman. The episodes here will be in simple English language (with few phrases and add ons of my favourite french language). The basic motto is to create an awareness and impart knowledge of the subject to all interested, concerned, curious and visitors. Pharmacology, the “SCIENCE OF DRUGS”, which hold an important place in everyone’s life. Here, I will discuss basic tips, strategies and ideas to study medical pharmacology easily and effectively especially for medical, nursing, dental and pharmacy schools and students. Even if you are not from Science stream, this information would be beneficial to you and therefore pay some valuable minutes to this Pharmacology Podcast, and you will not be in loss !! The descriptions will be short pieces of science work lengthy enough to engage you and not to test your patience! So, go ahead, lend your ears to these crispy informative audio files and empower and enrich your sea of knowledge and let me know “IS PHARMACOLOGY DIFFICULT?” For various links, please visit: https://linktr.ee/ispharmacologydifficult. Disclaimer: All the content of the podcast audio is expressed in my own language and learning and understanding viewpoints. References are from the best and reputed subject (Pharmacology) text books, blogs, journals and drug information from reputed and best online sources. I make best efforts to convey the most accurate and updated information of the subject of medical sciences in my special way. I take no money from pharmaceutical industry or drug companies for my podcast. You are most welcome to post your comments, suggestions, etc. through “Contact” page on my website: www.ispharmacologydifficult.com. You all are well known that medical sciences subjects are ever changing, updated and ever evolving, hence no guarantee is taken if the information conveyed in this podcast turns outdated or obsolete with changing and evolving times. This podcast is an expression of my learnings and experiences and in no way representative of any standard authority. Privacy Notice: I collect only email addresses of the subscribers and in no circumstances they will be shared or displayed anywhere on podcast/website/newsletter. Copyright & Distribution: All the contents of “IS PHARMACOLOGY DIFFICULT®️” podcast/website/blog/newsletter are copyrighted. Though all the content related to podcast and various social media handles is free! “BUT” in no way or under no circumstances shall- Any of the podcast content/show notes/blog post/newsletter content/youtube video artwork/podcast artwork and ideas should be used or reproduced or distributed.

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    Latest Episodes:
    Is Pharmacology Difficult Podcast PHARMACODYNAMICS-ENZYME INHIBITION Sep 05, 2021
    Show notes

    Would love to know your opinions & expectations -Dr Radhika Vijay

    Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay.
    Firstly its my great pleasure to wish all a very "HAPPY TEACHER'S DAY". Its a great day and yes I am here with a great discussion topic i.e. Enzyme Inhibition. First of all I will define as a ritual, then with no delay I will discuss its two main types, namely Competitive and Non Competitive Enzyme Inhibition. I will discuss their main features or characteristics, the basic mechanism and yes never to miss, never to forget the wonderful examples!
    For your utter knowledge, i want to state that Competitive Enzyme inhibition is again of two different kinds, namely Equilibrium and Non equilibrium type and they have their own properties, you need to know them all!
    The status of Km and Vmax changes for all types and thats worth noticing and remembering, in the end with glory and hail to all preachers and teachers, I will be winding and ending for the great fun filled Sunday! Hope you had a real nice one!
    For all the updates and latest episodes of my podcast, please visit www.ispharmacologydifficult.com where you can also sign up for a free monthly newsletter of mine. It actually contains lot of updates about the medical sciences, drug information and my podcast updates also.
    You can follow me on different social media handles like twitter, insta, facebook and linkedin. They all are with same name "IS PHARMACOLOGY DIFFICULT". If you are listening for the first time, do follow me here, whatever platform you are consuming this episode, stay tuned, do rate and review on ITunes, Apple podcasts, stay safe, stay happy, stay enlightened, Thank you!!

    You can access various links via

    https://linktr.ee/ispharmacologydifficult

    • Please leave Review on Apple podcasts!
    • My E-Newsletter sign up at Substack!
    • Connect on Twitter & Instagram!
    • My books on Amazon & Goodreads!
    Is Pharmacology Difficult Podcast PHARMACODYNAMICS-DRUG MECHANISMS Aug 26, 2021
    Show notes

    Would love to know your opinions & expectations -Dr Radhika Vijay

    Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay.
    In today's episode I will be further stating the essence of Pharmacodynamics especially the introductory part!
    Initially I will be stating various drug mechanisms like Activation, Inhibition, Complexation and Neutralisation. All discussion is supported with examples, then I will tell most importantly that Drug mechanism can be receptor or non receptor mediated.
    Then I will start off with Elaborations about Enzymes, very detailed and specific conversations about Enzyme Stimulation and Enzyme Induction, their essence and differences.
    All this talk will be the meat and potatoes of today's verbal session.
    Withdrawing my words after enlisting important enzyme inducers, I promise to continue in next episode, not making too much of the talk just for the sake of few minutes, hoping a magnificent, spiritual Thursday for all!!
    For all the updates and latest episodes of my podcast, please visit www.ispharmacologydifficult.com where you can also sign up for a free monthly newsletter of mine. It actually contains lot of updates about the medical sciences, drug information and my podcast updates also.
    You can follow me on different social media handles like twitter, insta, facebook and linkedin. They all are with same name "IS PHARMACOLOGY DIFFICULT". If you are listening for the first time, do follow me here, whatever platform you are consuming this episode, stay tuned, do rate and review on ITunes, Apple podcasts, stay safe, stay happy, stay enlightened, Thank you!!
    You can access various links via - https://linktr.ee/ispharmacologydifficult

    • Please leave Review on Apple podcasts!
    • My E-Newsletter sign up at Substack!
    • Connect on Twitter & Instagram!
    • My books on Amazon & Goodreads!
    Is Pharmacology Difficult Podcast INTRODUCTION TO PHARMACODYNAMICS Aug 13, 2021
    Show notes

    Would love to know your opinions & expectations -Dr Radhika Vijay

    Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay.
    In today's episode, I will be introducing Pharmacodyamics, definition, concept, and try to cover as one line statement, two line statement!!
    To begin with, today's little contemplation about Criticism, how big deal is it?, how important and wisely you can deal with it, is it really worth a panic? and much more!!
    And then as our topic proceeds, we will talk about the important drug actions like stimulation, depression, cytotoxicity, replacement, etc.
    And later I will cover important sites of drug action like Extracellular, Cellular and Intracellular!
    With these little but important concepts and knowledge bytes, I will be wrapping up with a great tip to be generous with praise and cautious with criticism, and pray and wow never to be trapped in either one!!
    For all the updates and latest episodes of my podcast, please visit www.ispharmacologydifficult.com where you can also sign up for a free monthly newsletter of mine. It actually contains lot of updates about the medical sciences, drug information and my podcast updates also.
    You can follow me on different social media handles like twitter, insta, facebook and linkedin. They all are with same name "IS PHARMACOLOGY DIFFICULT". If you are listening for the first time, do follow me here, whatever platform you are consuming this episode, stay tuned, do rate and review on ITunes, Apple podcasts, stay safe, stay happy, stay enlightened, Thank you!!

    You can access various links via

    https://linktr.ee/ispharmacologydifficult

    • Please leave Review on Apple podcasts!
    • My E-Newsletter sign up at Substack!
    • Connect on Twitter & Instagram!
    • My books on Amazon & Goodreads!
    Is Pharmacology Difficult Podcast THERAPEUTIC DRUG MONITORING (TDM) Aug 06, 2021
    Show notes

    Would love to know your opinions & expectations -Dr Radhika Vijay

    Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay.
    I welcome you all to make the podcast sound better cause its a Friday!!
    Singing the glory of being our best version throughout the week and a wish to start weekend afresh, I will introduce the topic of the day, its actually Therapeutic Drug Monitoring.
    As our custom, I will be defining it, tell you about its features, when it should be done, when its performance goes in vain and critical steps and conditions to monitor the time interval between drug administration and drawing sample for TDM!
    All this and much more wrapped up in today's episode rigmarole, Listen to unwind the unheard.....
    For all the updates and latest episodes of my podcast, please visit www.ispharmacologydifficult.com where you can also sign up for a free monthly newsletter of mine. It actually contains lot of updates about the medical sciences, drug information and my podcast updates also.
    You can follow me on different social media handles like twitter, insta, facebook and linkedin. They all are with same name "IS PHARMACOLOGY DIFFICULT". If you are listening for the first time, do follow me here, whatever platform you are consuming this episode, stay tuned, do rate and review on ITunes, Apple podcasts, stay safe, stay happy, stay enlightened, Thank you!!

    You can access various links via

    https://linktr.ee/ispharmacologydifficult

    • Please leave Review on Apple podcasts!
    • My E-Newsletter sign up at Substack!
    • Connect on Twitter & Instagram!
    • My books on Amazon & Goodreads!
    Is Pharmacology Difficult Podcast DOSING SCHEDULES-2 Jul 27, 2021
    Show notes

    Would love to know your opinions & expectations -Dr Radhika Vijay

    Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay.
    Marking the celebrated beginnings with essence of birthdays of dear ones, i will quickly follow the ritual of announcing the topic of the day that resounds like Dosing Schedules. In this head, i will talk about drugs having real long half lives, that is more than 24 hours. What are different guidelines, rules, regulations and criteria to administer such drugs especially when they have high volume of distribution. It would be great to discuss states like casual and emergency!
    And whether the person is considerably healthy or possess impaired renal and liver states , all these matter along with altered pharmacogenetic conditions!
    Lets spend some time dedicating to subjects essence while we hurry to join a much awaited celebration......
    For all the updates and latest episodes of my podcast, please visit www.ispharmacologydifficult.com where you can also sign up for a free monthly newsletter of mine. It actually contains lot of updates about the medical sciences, drug information and my podcast updates also.
    You can follow me on different social media handles like twitter, insta, facebook and linkedin. They all are with same name "IS PHARMACOLOGY DIFFICULT". If you are listening for the first time, do follow me here, whatever platform you are consuming this episode, stay tuned, do rate and review on ITunes, Apple podcasts, stay safe, stay happy, stay enlightened, Thank you!!

    You can access various links via

    https://linktr.ee/ispharmacologydifficult

    • Please leave Review on Apple podcasts!
    • My E-Newsletter sign up at Substack!
    • Connect on Twitter & Instagram!
    • My books on Amazon & Goodreads!
    Is Pharmacology Difficult Podcast DOSING SCHEDULES-1 Jul 19, 2021
    Show notes

    Would love to know your opinions & expectations -Dr Radhika Vijay

    Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay.
    In today's I will be covering details about Dosing schedules. I will be narrating definition, aims and objectives, different conditions and states as far as duration of half lives are concerned.
    You will notice how importantly duration of half life affects the route of drug administration, the frequency of dosing, the dosage form, the dosing schedule! Thats the essence of the topic, Later, I will be summarising important points with few more touch up information strokes, hope you all like it!
    For all the updates and latest episodes of my podcast, please visit www.ispharmacologydifficult.com where you can also sign up for a free monthly newsletter of mine. It actually contains lot of updates about the medical sciences, drug information and my podcast updates also.
    You can follow me on different social media handles like twitter, insta, facebook and linkedin. They all are with same name "IS PHARMACOLOGY DIFFICULT". If you are listening for the first time, do follow me here, whatever platform you are consuming this episode, stay tuned, do rate and review on ITunes, Apple podcasts, stay safe, stay happy, stay enlightened, Thank you!!

    You can access various links via
    https://linktr.ee/ispharmacologydifficult

    • Please leave Review on Apple podcasts!
    • My E-Newsletter sign up at Substack!
    • Connect on Twitter & Instagram!
    • My books on Amazon & Goodreads!
    Is Pharmacology Difficult Podcast PLASMA HALF LIFE OF DRUG-1 Jul 08, 2021
    Show notes

    Would love to know your opinions & expectations -Dr Radhika Vijay

    Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay.
    In today's episode, I will be emphasizing on the value of Wait, Patience and waiting for worthwhile things in life! That actually makes a lot of sense!
    The heading of today's talk dancing in fonts is the "plasma half life of drug".
    To start with, its a good ritual to define the topic and then discuss the minute details, and so will I do. After definition, I will be focussing on deriving a formula for the same and very efficiently will accomplish it. You can actually calculate t1/2 of a drug by knowing parameters like Clearance and Volume of distribution. Next I will be talking about differences regarding first order and second order elimination kinetics. Then I will be covering topics like "Repeated drug administration", "Steady state plasma concentration" and "Plateau principle" in depth of conversation. To brush up, a few concepts will be listed, and then and there I will wrap it all for the day, making episodes lengthy is simply testing the comprehension capacity of mind which shouldn't be exhausted!With the idea of covering a couple of few more episodes in the same stream of topic, I will wave a bye! Have a chocolate on the "CHOCOLATE DAY" and stay sweet in conversation, thats too an art! Right?
    For all the updates and latest episodes of my podcast, please visit www.ispharmacologydifficult.com where you can also sign up for a free monthly newsletter of mine. It actually contains lot of updates about the medical sciences, drug information and my podcast updates also.
    You can follow me on different social media handles like twitter, insta, facebook and linkedin. They all are with same name "IS PHARMACOLOGY DIFFICULT". If you are listening for the first time, do follow me here, whatever platform you are consuming this episode, stay tuned, do rate and review on ITunes, Apple podcasts, stay safe, stay happy, stay enlightened, Thank you!!

    You can access various links via

    https://linktr.ee/ispharmacologydifficult

    • Please leave Review on Apple podcasts!
    • My E-Newsletter sign up at Substack!
    • Connect on Twitter & Instagram!
    • My books on Amazon & Goodreads!
    Is Pharmacology Difficult Podcast ZERO ORDER ELIMINATION KINETICS Jun 28, 2021
    Show notes

    Would love to know your opinions & expectations -Dr Radhika Vijay

    Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay.
    In today's episode I will be emphasizing the essence and feel of returning home after long work hours or days out, its actually great and conveyed today in a quite melodious way!! Hope you all like it.
    Today's topic is Zero Order Elimination Kinetics. I will discuss the importance, examples and very nicely describe the mechanism and characteristics in bullet points. The effect on half life, clearance , all will be crystal clear. I will be justifying the different names given to this elimination kinetics like Mixed Order kinetics, Michaelis Menten Kinetics, Capacity Limited Elimination and Non Linear Elimination.All in in all The end statements will be dedicated to blood flow dependent elimination and reviving the strong feel while way back home in verses of Boyzone classical band, I will call it for the day!!
    For all the updates and latest episodes of my podcast, please visit www.ispharmacologydifficult.com where you can also sign up for a free monthly newsletter of mine. It actually contains lot of updates about the medical sciences, drug information and my podcast updates also.
    You can follow me on different social media handles like twitter, insta, facebook and linkedin. They all are with same name "IS PHARMACOLOGY DIFFICULT". If you are listening for the first time, do follow me here, whatever platform you are consuming this episode, stay tuned, do rate and review on ITunes, Apple podcasts, stay safe, stay happy, stay enlightened, Thank you!!

    You can access various links via

    https://linktr.ee/ispharmacologydifficult

    • Please leave Review on Apple podcasts!
    • My E-Newsletter sign up at Substack!
    • Connect on Twitter & Instagram!
    • My books on Amazon & Goodreads!
    Is Pharmacology Difficult Podcast FIRST ORDER ELIMINATION KINETICS Jun 22, 2021
    Show notes

    Would love to know your opinions & expectations -Dr Radhika Vijay

    Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay.
    Today I will be emphasizing on the upper hand power of listening over hearing!
    Yes, both are so different, we actually rarely listen!!
    Today, I want you all to listen to me. What are the different features of First order kinetics of elimination and what is the essence of knowing it all? All these quests will be resolved in today's episode.
    No delays and i will break into the features straightaway of First Order Kinetics of Elimination with the examples , the concept gonna be crystal clear!
    You are expected to listen today nicely all the points or characteristics or features of First order kinetics of Elimination because most of the drugs are following it!
    I will be explaining thoroughly the relation to plasma half life, the dose concentration time curve, its plotting in logarithmic form and how it becomes so important. I will clearly in depth dive into the two slopes of drug clearance, the alpha and beta slopes and will tell you the difference in distribution and elimination half lives, their importance and relevance .
    Its gonna be a good package of knowledge and information for Tuesday! In no mood to commence the topic of plasma half life today, I will be setting the enunciation into recess till my next convo voice expected to reverb very soon!! With the expectations that you gonna make the most of your talents today, a thoughtful bbyee..
    For all the updates and latest episodes of my podcast, please visit www.ispharmacologydifficult.com where you can also sign up for a free monthly newsletter of mine. It actually contains lot of updates about the medical sciences, drug information and my podcast updates also.
    You can follow me on different social media handles like twitter, insta, facebook and linkedin. They all are with same name "IS PHARMACOLOGY DIFFICULT". If you are listening for the first time, do follow me here, whatever platform you are consuming this episode, stay tuned, do rate and review on ITunes, Apple podcasts, stay safe, stay happy, stay enlightened, Thank you!!

    You can access various links via

    https://linktr.ee/ispharmacologydifficult

    • Please leave Review on Apple podcasts!
    • My E-Newsletter sign up at Substack!
    • Connect on Twitter & Instagram!
    • My books on Amazon & Goodreads!
    Is Pharmacology Difficult Podcast KINETICS OF DRUG ELIMINATION-DRUG CLEARANCE Jun 17, 2021
    Show notes

    Would love to know your opinions & expectations -Dr Radhika Vijay

    Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay.
    In today's episode, I will be emphasizing the hand in hand coordination of knowledge and wisdom. To start with, I will tell you the essence of knowledge of Drug elimination kinetics. I will define the topics and areas it covers, what all and why do we need to know it thoroughly!!
    The beginnings will be stated by defining the subhead for the day and it sounds like 'Drug Clearance". I will first be defining it, then I will give the formula for it. Next, I will be telling you about important implications and noteworthy essence of different aspects, situations and conditions of clearance!
    What concerns and cautions govern the drug administration? How does the clearance refers to creatinine clearance? All will be made crystal clear. In a way, I will put your brains to exercise for computing the sumtotal value of clearance by knowledge of renal and hepatic clearance. With signature remarks about the values of renal clearance in relation to Glomerular filtration Rate and tubular secretion and before that a few comments about plasma half life, I will be calling it for the day, hope you find a certain meaningful value out of today's convo..,till we chat next, a soft bbyee....
    For all the updates and latest episodes of my podcast, please visit www.ispharmacologydifficult.com where you can also sign up for a free monthly newsletter of mine. It actually contains lot of updates about the medical sciences, drug information and my podcast updates also.
    You can follow me on different social media handles like twitter, insta, facebook and linkedin. They all are with same name "IS PHARMACOLOGY DIFFICULT". If you are listening for the first time, do follow me here, whatever platform you are consuming this episode, stay tuned, do rate and review on ITunes, Apple podcasts, stay safe, stay happy, stay enlightened, Thank you!!

    You can access various links via

    https://linktr.ee/ispharmacologydifficult

    • Please leave Review on Apple podcasts!
    • My E-Newsletter sign up at Substack!
    • Connect on Twitter & Instagram!
    • My books on Amazon & Goodreads!
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