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    Science

    Hold That Thought

    Hold That Thought brings you research and ideas from Arts & Sciences at Washington University in St. Louis. Throughout the year we select a few topics to explore and then bring together thoughtful commentary on those topics from a variety of experts and sources. Be sure to subscribe!

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    Latest Episodes:
    Metabolism: The Google Maps of Cancer Research Dec 02, 2016
    Show notes

    When you hear the word "metabolism," what do you think about? Thanks to the groundbreaking work of chemist Gary Patti here at Washington University in St. Louis, instead of diet or weight loss, we think: "possible cure for cancer." Patti explains how metabolism is like Google Maps, helps us understand the emerging field of metabolomics, and shares the challenges and promise of metabolism research.


    Pilgrim Fathers, How The Thanksgiving We Know And Love Was Manufactured Nov 23, 2016
    Show notes

    Thanksgiving is a day most Americans look forward to, a day of watching parades and feasting on delicious food with friends and family. However, the rosy picture we have in our minds of our Pilgrim forefathers sitting down to eat with the local Native American tribes is, frankly, a myth. In honor of the holiday, American religious historian Mark Valeri shares the true and harrowing tales of the Pilgrim immigrants, and how and why their story came to national prominence in the post-Civil War era. He also examines how the myth of that first Thanksgiving has taken root in the American identity, and traces the revisions the story has undergone through the decades. This episode was first released in 2015.


    A Chemist's Quest for New Antibiotics Nov 14, 2016
    Show notes

    Remember the last time you were sick and your doctor gave you antibiotics? What might have happened if those drugs didn't work? As antibiotic-resistant bacteria spread around the world, this scenario is much more than a "what if." The World Health Organization calls antibiotic resistance "one of the biggest threats to global health, food security, and development today." To mark World Antibiotic Awareness Week, chemist TIm Wencewicz explains how we got here, why big pharmaceutical companies are neglecting the problem, and what his lab is doing to solve it.


    Social Citizens: How Peer Networks Influence Elections Nov 03, 2016
    Show notes

    When you walk into a voting booth in less than a week to vote for the future president of the United States, you'll be all by yourself making a very personal decision - right? Betsy Sinclair, a political scientist at Washington University in St. Louis and author of The Social Citizen: Peer Networks and Political Behavior, believes that in reality, politics is often more social than personal. Here she discusses the place of Facebook, YouTube, and face-to-face interactions in political decision-making, and explains how social science experiments reveal the true importance of social networks in politics.


    "Do You Like Scary Movies?" Horror Films & Things That Make Us Scream Oct 26, 2016
    Show notes

    Horror movies have been drawing audiences since the earliest days of film. But why are we drawn to fictional portrayals of events that we'd do anything to avoid in real life? And are we frightened by the same things we were 20 years ago? John Powers walks us through the history of the horror film genre. From the Frankenstein and Nosferatu to Freddy Krueger and Bruce Campbell, we break down what makes us scream.


    Slavery at Sea Oct 19, 2016
    Show notes

    In her new book Slavery at Sea: Terror, Sex, and Sickness in the Middle Passage, historian Sowande' Mustakeem reveals the forgotten world of 18th century slave ships. Here, she shares the tragic story of one enslaved woman and discusses why it's so important for Americans to confront this foundational, brutal chapter of history. Mustakeem's research focuses on the experiences of those most frequently left out of the history of the Middle Passage - women, children, the elderly, and the diseased. A version of this episode was first released in 2013, in our American Identities series.


    The Hidden History of Trumpism Oct 13, 2016
    Show notes

    In a recent article in the Guardian, postdoctoral fellow Tim Shenk argues that Donald Trump's rise within the Republican Party has historical - and often overlooked - roots. From an obscure online journal to a best-selling book from 1941 and beyond, Shenk traces the hidden and surprising intellectual path of what we now call Trumpism. Understanding this history, Shenk believes, helps illuminate Trump's popularity, his reliance on Twitter, his clashes with fellow Republicans, and more.


    A Laboratory for the Social Sciences: The American Panel Survey Oct 05, 2016
    Show notes

    What does the average American voter really think about the 2016 presidential candidates? How much do those beliefs depend on things like income, education level, or even personality? With the American Panel Survey (or TAPS), social scientists have a powerful tool to explore questions about human attitudes and behaviors over time. This year, researchers are using TAPS to learn about why voters choose certain candidates over others, and when and why they sometimes change their minds. Steven Smith, the director of TAPS, explains how the survey works and why it's such an asset for social scientists.


    How to Forecast an Election Sep 29, 2016
    Show notes

    It's about six weeks until the 2016 US presidential election, and everyone wants to know: Who will win? Hillary Clinton? Or Donald Trump? To attempt to answer this question, political scientists like Jacob Montgomery build complex forecasting models. Montgomery shares his own unique approach to forecasting, and describes both the limitations and the value of these efforts to predict the future.


    Milk at Altitude: Exploring Health in the Himalayas Sep 22, 2016
    Show notes

    Scientists agree that breast milk is good for babies, but E.A. Quinn believes there's a lot more to learn. Join Quinn on a recent research trip to a remote valley in Nepal, where she works with community partners to understand the health of mothers and infants under extreme conditions. How is human milk different in the Himalayan highlands than in the United States? What can these differences reveal about what moms and babies everywhere need to be healthy? Hear Quinn describe her fieldwork, what she's found out so far, and why she's so fascinated by this "incredible fluid."


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