Healthcare Unfiltered

Latest Episodes:

Episode 269: The Pain Brokers and Tort Law With Beth Burch Mar 03, 2026

Show notes

Chadi sits down with award-winning legal scholar Elizabeth (Beth) Chamblee Burch to explore “The Pain Brokers: How Con Men, Call Centers, and Rogue Doctors Fuel America’s Lawsuit Factory,” her deeply reported investigation into a multilevel scam involving a pelvic mesh product that preyed on vulnerable patients and exploited mass tort litigation. Together, they discuss how she uncovered her sources and evidence, the harrowing stories of the women caught up in this web of telemarketing, shady medical referrals, and legal profiteering, and what the fallout reveals about the broader tort law system.
Read more about The Pain Brokers.
https://www.simonandschuster.com/books/The-Pain-Brokers/Elizabeth-Chamblee-Burch/9781668068861
Check out Chadi’s website for all Healthcare Unfiltered episodes and other content. https://www.chadinabhan.com/
Watch all Healthcare Unfiltered episodes on YouTube. https://www.youtube.com/channel/UCjiJPTpIJdIiukcq0UaMFsA

Episode 268: Everything ADCs in Cancer With Paolo Tarantino Feb 24, 2026

Show notes

Paolo Tarantino, MD, PhD, medical oncologist at Dana-Farber Cancer Institute, joins Chadi for a deep dive into the rapidly evolving world of antibody-drug conjugates (ADCs)—sometimes dubbed “super-chemotherapies.” He traces the fascinating origins of the ADC concept, including a centuries-old scientific insight that foreshadowed their development, and explains the biology behind how these targeted therapies deliver potent cytotoxics directly to cancer cells across tumor types. Dr. Tarantino also reflects on launching his career alongside the infancy of modern ADCs, explores innovations like multi-payload constructs, and weighs in on whether ADCs could ultimately replace conventional chemotherapy as research continues to push the field forward.
Check out Chadi’s website for all Healthcare Unfiltered episodes and other content. https://www.chadinabhan.com/
Watch all Healthcare Unfiltered episodes on YouTube. https://www.youtube.com/channel/UCjiJPTpIJdIiukcq0UaMFsA

Episode 267: State of Peer Review and Medical Publishing With Nora Disis Feb 17, 2026

Show notes

Chadi sits down with Nora Disis, MD—Editor in Chief of JAMA Oncology and professor at Fred Hutchinson Cancer Center—for a candid, wide-ranging discussion on the modern state of peer review and medical publishing. Dr. Disis reflects on the founding of JAMA Oncology and her role as its inaugural Editor in Chief, then pulls back the curtain on what actually happens when a manuscript is submitted (yes, she reads every one), how impact factors shape—and sometimes distort—the field, and what truly defines a high-quality peer reviewer. From the promises and pitfalls of AI to the pressures facing academic publishing today, this is a raw, thoughtful, and at times critical look at how medical evidence gets vetted and shared with the world.
Check out Chadi’s website for all Healthcare Unfiltered episodes and other content. https://www.chadinabhan.com/
Watch all Healthcare Unfiltered episodes on YouTube. https://www.youtube.com/channel/UCjiJPTpIJdIiukcq0UaMFsA

Episode 266 - History of Viruses: Kill Switch Feb 10, 2026

Show notes

Award-winning stem cell transplant pioneer, Dr. Richard Burt, discusses his book “Kill Switch: The History of How Viruses Shaped Humanity and Led to COVID-19,” guiding listeners through the deep, often surprising role viruses like smallpox, polio, HIV, and COVID-19 have played in shaping human civilization and global health responses. With factual clarity and a historian’s eye, Dr. Burt explains the development of scientific understanding and vaccines without political agenda, offering historical perspective that sheds light on the ups and downs of vaccine innovation and what we can learn from the COVID-19 era.
Find out more about the book.
https://store.poisonedpen.com/item/Oz7LbGTIpIiC-va1OfEOpQ
Check out Chadi’s website for all Healthcare Unfiltered episodes and other content. https://www.chadinabhan.com/
Watch all Healthcare Unfiltered episodes on YouTube. https://www.youtube.com/channel/UCjiJPTpIJdIiukcq0UaMFsA

Episode 265: ASCO GI Updates: Special Episode Feb 05, 2026

Show notes

Drs. Shaalan Beg, Shruti Patel, and Emil Lou—the “Only Oncologists in the Building”—offer an in-depth, clinically focused review of the most important research presented at the ASCO GI Annual Meeting. The conversation spans the rising incidence and outcomes of early-onset colorectal cancer, survivorship considerations, and a nuanced discussion of ctDNA in the adjuvant setting for high-risk stage II disease, including whether its role has evolved from purely prognostic to truly predictive. They also critically analyze practice-defining trials such as BREAKWATER in BRAF V600E–mutated metastatic colorectal cancer, COMMIT in dMMR/MSI-H disease, upper GI studies including HORIZON-GEA-01, MATTERHORN, and ILUSTRO, along with meaningful updates in pancreatic and hepatobiliary cancers—ultimately weighing which data should influence clinical practice today versus what remains on the horizon.
View content from “The Only Oncologists In the Building.”
https://www.youtube.com/@OnlyOncs/videos
Check out Chadi’s website for all Healthcare Unfiltered episodes and other content. https://www.chadinabhan.com/
Watch all Healthcare Unfiltered episodes on YouTube. https://www.youtube.com/channel/UCjiJPTpIJdIiukcq0UaMFsA

Episode 264: Oncology Career Paths With the Two Onc Docs Feb 03, 2026

Show notes

In this cross-collaboration episode, Drs. Sam Armstrong and Karine Tawagi—hosts of the “Two Onc Docs” podcast—join the show to share their personal journeys into oncology and the inspiration behind launching a podcast for the oncology community. The conversation then expands into a candid, practical discussion of oncology career paths, offering fellows and early-career physicians real-world guidance on choosing a first job, negotiating contracts and compensation, evaluating mentorship, and balancing professional goals with life outside of medicine. From academic practice to alternative stakeholder roles, this honest dialogue unpacks the many decisions that shape a sustainable and fulfilling career in medicine.
Listen to “Two Onc Doc” episodes.
https://podcasts.apple.com/us/podcast/two-onc-docs/id1616541733
Check out Chadi’s website for all Healthcare Unfiltered episodes and other content. www.chadinabhan.com/
Watch all Healthcare Unfiltered episodes on YouTube. www.youtube.com/channel/UCjiJPTpIJdIiukcq0UaMFsA

Episode 263: ADCs in Breast Cancer: What to Know With VK Gadi Jan 27, 2026

Show notes

VK Gadi, MD, PhD, of the University of Illinois Cancer Center, joins the show for a deep dive into antibody-drug conjugates (ADCs) in breast cancer, tracing the history and basic science that fueled their development and early interest in the field. Dr. Gadi breaks down where ADCs currently fit in breast cancer care, including key toxicities, evolving data presented at ESMO, and findings that may support FDA approval in early-stage and neoadjuvant HER2-positive disease. The conversation also explores advances in TROP-2–expressing and HER2-low disease, along with practical insights on incorporating and sequencing these agents in earlier lines of therapy.
Check out Chadi’s website for all Healthcare Unfiltered episodes and other content. www.chadinabhan.com/
Watch all Healthcare Unfiltered episodes on YouTube. www.youtube.com/channel/UCjiJPTpIJdIiukcq0UaMFsA

Episode 262: MRD and ctDNA in Lymphoma With Megan Melody Jan 20, 2026

Show notes

Returning guest Megan Melody, MD—lymphoma and CAR-T hematologist at Tampa General Hospital and the University of South Florida—joins the show for a practical, data-driven discussion on the evolving role of measurable residual disease (MRD) and circulating tumor DNA (ctDNA) in lymphoma. The conversation explores which lymphoma subtypes benefit most from MRD assessment, the available commercial assays and their sensitivity and specificity, how MRD and PET imaging should be used together (or not), and how to manage real-world scenarios such as PET-positive/ctDNA-negative patients at the end of therapy. Dr. Melody also reviews NCCN guidance, emerging frontline data in large B-cell lymphoma, and how both academic and community clinicians can translate these tools into everyday treatment decisions.
Check out Chadi’s website for all Healthcare Unfiltered episodes and other content. www.chadinabhan.com/
Watch all Healthcare Unfiltered episodes on YouTube. www.youtube.com/channel/UCjiJPTpIJdIiukcq0UaMFsA

Episode 261: Rebooting Cancer Care With Doug Flora Jan 13, 2026

Show notes

Returning guest Doug Flora, MD, LSSBB, practicing oncologist and healthcare innovator, joins the show to discuss his new book Rebooting Cancer Care and his pragmatic vision for how artificial intelligence is reshaping oncology today. Dr. Flora explores how AI is already being leveraged to accelerate drug discovery and development, redesign smarter clinical trials, and support more informed, efficient decision-making—while emphasizing that these tools are meant to augment and “save” the oncologist, not replace them. Written for clinicians, industry leaders, patients, and caregivers alike, his book breaks down complex technology into accessible insights, highlighting how AI can reduce burnout, restore human connection in care, and help build a more sustainable, patient-centered cancer ecosystem.
View more about the book.
www.dougflora.com/
Check out Chadi’s website for all Healthcare Unfiltered episodes and other content. www.chadinabhan.com/
Watch all Healthcare Unfiltered episodes on YouTube. www.youtube.com/channel/UCjiJPTpIJdIiukcq0UaMFsA

Episode 260: TNBC Now and the Future With Greg Vidal Jan 06, 2026

Show notes

Chadi sits down with Gregory Vidal, MD, PhD, medical oncologist at the West Cancer Center, for a comprehensive, state-of-the-field discussion on triple-negative breast cancer (TNBC). Dr. Vidal walks listeners through how TNBC emerged as a diagnosis of exclusion, who is most commonly affected, current treatment paradigms and sequencing in early-stage and metastatic disease, and key considerations around surgery, recurrence risk, and unresolved questions. The conversation also explores modern decision-making in metastatic TNBC, including PD-L1 testing, first- and second-line strategies, antibody–drug conjugates versus chemotherapy, PARP inhibitors for BRCA-mutated disease, and the critical role of clinical trials in shaping the future of care.
Check out Chadi’s website for all Healthcare Unfiltered episodes and other content. www.chadinabhan.com/
Watch all Healthcare Unfiltered episodes on YouTube. www.youtube.com/channel/UCjiJPTpIJdIiukcq0UaMFsA

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