GI Pearls Podcast

GI Pearls Gastroenterology Podcast Episode 63 Aug 26, 2023

Show Notes for Episode 63 of GI Pearls

Artificial intelligence- aided colonoscopy does not increase adenoma detection rate in routine clinical practice – Am J Gastr
Estimated Burden of Screening for Barrett’s Esophagus in the United States – Gastro
Carvedilol Achieves Higher Hemodynamic Response and Lower Rebleeding Rates Than Propranolol in Secondary Prophylaxis – CGH
Screening for Colorectal Cancer – ACP Guidance Statement – Annals of IM
Cold snare versus cold forceps polypectomy for endoscopic resection of diminutive polyps: meta-analysis of randomized controlled trials. – GIE

GI Pearls Gastroenterology Podcast Episode 62 Jul 15, 2023

Episode 62 Show Notes July 2023

Comparison of endoscopic sleeve gastroplasty versus surgical sleeve gastrectomy: a database analysis. – GIE
Incidence and natural history of gastric high grade dysplasia in patients with FAP. – GIE
Association of Life Expectancy with surveillance colonoscopy findings and follow up recommendations in Older adults – Jama IM
Physician decision-making about surveillance in older adults with prior adenomas: results from a national study. – Am J Gastro
Hpylori eradication for primary prevention of peptic ulcer bleeding in older patients prescribed aspirin in primary care (HEAT) – RCT – Lancet 2022
Effectiveness and Safety of Colonic and Capsule Fecal Microbiota Transplantation for Recurrent Clostridiodes difficile Infection – CGH

GI Pearls Gastroenterology Podcast Episode 61 Jun 05, 2023

Episode 61 Show Notes June 2023

GI Pearls Gastroenterology Podcast Episode 60 Oct 22, 2022

Show Notes for GI Pearls Episode 60

What is the Prevalence of Clinically Significant Endoscopic Findings in Subjects With Dyspepsia? Updated Systematic Review and Meta-analysis – CGH
Quality of upper GI endoscopy: a prospective cohort study on impact of endoscopist education – GIE
Association between endoscopist specialty and colonoscopy quality: a systematic Review and meta-analysis. – CGH
Net Remission Rates with Biologic Treatment in Crohn’s Disease: A Reappraisal of the Clinical Trial Data – CGH

GI Pearls Gastroenterology Podcast Episode 59 Short Sep 25, 2022

Show notes for Episode 59 GI Pearls Podcast

Cannabidiol for Functional Dyspepsia With Normal Gastric Emptying: a RCT. – Am J Gastro
Randomized Controlled Trial Investigating Cold Snare and Forceps Polypectomy among small POLYPs in Rates of Complete Resection: The TINYPOLYP Trial – Am J Gastro
Vonoprazan triple and dual therapy for Hpylori infection in the United States and Europe: RCT – Gastro
Aggressive or Moderate Fluid Resuscitation in Acute Pancreatitis – NEJM

GI Pearls Gastroenterology Podcast Episode 58 Short Sep 11, 2022

Episode 58 Show notes

Cold versus hot snare resection with or without submucosal injection of 6-15mm colorectal polyps: RCT. – GIE
Prospective cohort study to investigate the safety of preoperative tumor necrosis factor inhibitor exposure in patients with inflammatory bowel disease undergoing intra-abdominal surgery. – Gastroenterology
Clip Closure does not reduce risk of bleeding after resection of large serrated polyps: Results from a randomized trial. – CGH

GI Pearls Episode 57 Short Aug 28, 2022

Articles discussed

Clinically significant serrated polyp detection rates and risk for postcolonoscopy colorectal cancer: data from the New Hampshire Colonoscopy Registry – GIE
Polyps seen but not removed during index colonoscopy: an underestimated inefficiency in endoscopy practice. – GIE
Fecal Microbiota transplant is a good treatment for recurrent C.difficile and there were several randomized clinical trials showing it’s efficacy, mostly small, but with really good results.

Please send me comments, suggestions to info@gipearls dot com. If you could also leave a good review on iTunes or your podcatcher of choice – this would go a long way.

GI Pearls Gastroenterology Podcast Episode 56 - Short Aug 13, 2022

Episode 56 – New Short Format

Articles discussed:

Once-only colonoscopy or two rounds of faecal immunochemical testing 2 years apart for colorectal cancer screening: preliminary report of a randomised controlled trial – Lancet Gastro Hep
Vedolizumab is associated with a lower risk of Serious Infectious than Anti-Tumor Factors Agents in Older Adults – CGH

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Episode 55 – June 2022 – Gastroenterology Literature Review Jun 05, 2022

Show notes for Episode 55 – June 2022

Pooled Rates of Adenoma Detection by Colonoscopy in Asymptomatic Average Risk Individuals with Positive Fecal Immunochemical Test: A Systematic Review and Meta-Analysis – GIE
Long-Term Follow-up of the Italian Flexible Sigmoidoscopy Screening Trial – Annals of IM
Recurrence of Colorectal neoplastic polyps after incomplete resection – annals of internal Medicine
A randomised controlled study shows supplementation of overweight and obese adults with lactobacilli and bifidobacteria reduces bodyweight and improves well-being – Scientific Reports
Associations between autoimmune conditions and gastric cancer risk among elderly adults in the united states – Am J Gastro
Patient satisfaction of Propofol versus Midazolam and Fentanyl Sedation during colonoscopy in IBD – CGH
Comorbidities Drive the Majority of Overall Mortality in Low-risk Mucinous Pancreatic Cysts Under Surveillance – CGH
Implications of stable or increasing adenoma detection rate on the need for continuous measurement. – GIE
Margin marking before colorectal endoscopic mucosal resection and its impact on neoplasia recurrence. – GIE
Percutaneous Tibial nerve Stimulation vs Sham Stimulation For Fecal incontinence in Women: Neuromodulation for accidental bowel leakage Randomized Clinical Trial – ACG
ACG-CAG Clinical Practice Guideline :Management of Anticoagulants and Antiplatelets during acute GI bleed – ACG Guidelines

Episode 54 – May 2022 – Gastroenterology Literature Review May 02, 2022

Show notes Episode 54 – May 2022

A Randomized Controlled Trial of Cold Snare Polypectomy Technique: Technique Matters More Than Snare Wire Diameter – Am J Gastro
Outcomes for upper gastrointestinal bleeding during the first wave of the COVID-19 pandemic in the Toronto area – J Gastro and Hep
Endoscopic Surveillance of Barrett’s Esophagus – using old principles and new technology to improve Care. – Am J Gastro
Three signs of pneumoperitoneum on a Supine Radio-graph – CGH
Comparison of a Hemostatic Powder and Standard Treatment in the Control of Active Bleeding From Upper Nonvariceal Lesions – Annals of Int Medicine
Associations Between Sleep Position and Nocturnal Gastroesophageal Reflux: A Study Using Concurrent Monitoring of Sleep Position and Esophageal pH and Impedance – ACG
Artificial intelligence for the assessment of bowel preparation – GIE
Diagnostic Yeild of colonoscopy in Patients with Symptoms Compatible with Rome IV Functional Bowel Disorders . – CGH

GI Pearls Gastroenterology Podcast Episode 53 - February 2022 Feb 22, 2022

Show Notes for Episode 53

Lyophilised oral fecal microbiota transplantation for ulcerative colitis (LOTUS): a randomised, double-blind, placebo-controlled trial. – Lancet Gastro
Effect of prophylactic endoscopic clip placement on clinically significant post-endoscopic mucosal resection bleeding in the right colon: a single centre, randomized controlled trial – Lancet Gastro
Feasibility and diagnostic yield of small-bowel capsule endoscopy in patients with surgically altered gastric anatomy: the SAGA study – GIE
Utility of Serum Biomarker Indices for staging of Hepatic Fibrosis before and after venesection in patients with Hemochromatosis caused by Variants in HFE – CGH
Barrett’s esophagus with low-grade dysplasia: high rate of upstaging at Barrett’s esophagus referral units suggests progression rates may be overestimated. – GIE
ACG Clinical Guideline for the diagnosis and management of GERD – Am J Gastro
Diagnosis and Management of Acute Left-Sided Colonic Diverticulitis: A Clinical Guideline From the American College of Physicians – ACP – Annals of IM

GI Pearls Gastroenterology Podcast Episode 52 - November 2021 Nov 20, 2021

Episode 52 Show notes

Immediate versus Postponed Intervention for Infected Necrotizing Pancreatitis – NEJM
Benchmarking Adenoma Detection Rates for Colonoscopy: Results From a US-Based Registry – Am J Gastro
Colonoscopy-related Mortality in a Fecal-Immunochemical Test-based Colorectal Cancer Screening Program – CGH
AGA Clinical Practice Update on Endoscopic Surveillance and Management of Colorectal Dysplasia in IBD – expert review – Gastro
Should Treatment Indications for Chronic Hepatitis B be Expanded? – CGH
Urinary Cannabis Metabolite Concentrations in Cannabis Hyperemesis Syndrome – JPGN
A randomized, Controled Trial of the Pan-PPAR Agonist Nanifibranor in NASH – NEJM
Prospective study of Outcomes in Adults with Nonalcoholic Fatty Liver Disease – NEJM
Recommendation Reversals in Gastroenterology Clinical Practice Guidelines – J of Canadian A of Gastro

GI Pearls Gastroenterology Podcast Episode 50 - September 2021 Sep 30, 2021

Show notes for Episode 51

Role of routine second-look endoscopy in patients with acute peptic ulcer bleeding: meta-analysis of randomized controlled trials- GIE
A Randomized Trial Comparing the Specific Carbohydrate Diet to a Mediterranean Diet in Adults with Crohn’s Disease – Gastroenterology
Comparative effectiveness and harms of antibiotics for outpatient diverticulitis. – Annals of IM
Colonoscopy Versus Fecal Immunochemical Test for Reducing Colorectal Cancer Risk: A Population-Based Case–Control Study – CTG
Combination therapy does not improve rate of clinical or endoscpic remission in patients with IBD treated with vedolizumab or ustekinumab. – CGH
World Gastroenterology Organisation Global Guidelines – Helicobacter Pylori May 2021
Gene-Specific Variation in Colorectal Cancer Surveillance Strategies for Lynch Syndrome
Association between time to colonoscopy after positive fecal testing and colorectal cancer outcomes: Review – CGH
Intestinal Failure: What all gastroenterolgists should know- CGH
ACG Clinical Guidelines: Prevention, Diagnosis and TReatment of Clostridioides difficile Infections – Am J Gastro

GI Pearls Gastroenterology Podcast Episode 50 - May 2021 May 25, 2021

Histologic Changes caused by Injection of a novel submucosal lifting agent for endoscopic resection in GI lesions. – GIE
Prevalence of Barrett’s Esophagus and performance of societal screening guidelines in an unreferred Primary care Population of US veterans. – GIE
The usefulness of olive oil enema in children with severe chronic constipation – J Ped Surg
Rates of Postoperative Recurrence of Crohn’s Disease and Effects of Immunosuppresive and Biologic Therapies – CGH
Histopathologic features and fragmentation of polyps with cold snare defect protrusions. – GIE
AGA Clinical Practice Update on Diagnosis and Management of Immune Checkpoint Inhibitor Colitis – Gastro
Management and outcomes of bleeding within 30 days of colonic polypectomy in a Large, Real-Life, Multicenter Cohort study. – CGH
Hypothermic Machine Perfusion in Liver Transplantation – NEJM
EUS-guided gallbladder drainage vs laparoscopic cholecystectomy for acute cholecystitis: a propensity score analysis with 1-year follow up data. – GIE
The prevalence of small-bowel polyps on video capsule endoscopy in patients with sporadic duodenal or ampullary adenomas. – GIE
Adverse events and residual lesions rate after cold endoscopic mucosal resection of serrated lesions >10mm.
Colorectal EMR outcomes in octogenarians versus younger patients referred for removal of large (>20mm) non-pedunculated polyps. – GIE

GI Pearls Gastroenterology Podcast Episode 49 - April 2021 Apr 14, 2021

Show notes for Episode 49 for April 2021

Effectiveness of Oral Vancomycin for Prevention of Healtchare Facility-onset C.diff infection in Targeted Patients during Systemic antibiotic Exposure – Clinical ID
The Detrimental Effects of oral Vancomycin – Letter to Editor – Clinical ID
Linked color imaging focused on Neoplasm detection in the Upper GI tract – randomised trial – Annals of Internal Medicine
AGA clinical Practice Update on Medical Management of Colonic Diverticulitis: Expert Review
Comparative effectiveness and harms of antibiotics for outpatient diverticulitis: Two nationwide cohort studies. Ann Intern Med
Effects of Tenofovir vs Entecavir on Risk of HCC in patients with chronic HBV infection: A SRMA – CGH
Factors that affect adequacy of Colon cleansing for colonoscopy in Hospitalized Patients – CGH
https://app.calculoid.com/#/calculator/69490
ACG Clinical Guidelines: Colorectal Cancer Screening 2021

GI Pearls Gastroenterology Podcast Episode 48 - March 2021 Feb 28, 2021

Show notes for Episode 48 March 2021

Younger physicians and longer withdwaral times are associated with detection of advanced neoplasia in a large community practice. – CGH
It’s All The RAVE: Time to Give up on “Chronic Radiation Proctitis” Misnomer – Gastroenterology
Local immune response to food antigens drives meal-induced abdominal pain – Nature
Prevalence of a First-Degree Relative with Colorectal Cancer and Uptake of screening among persons 40-54 years old. – CGH
Prevalence of IBS-type symptoms in patients with IBD in remission: SRMA – Lancet:Gastro and Hep
Impact of 9-Minute Withdrawal Time on the Adenoma Detection Rate: A Multicenter Randomized Controlled Trial – CGH
Use of proton pump inhibitors to treat persistent throat symptoms: multicentre, double blind, randomised, placebo controlled trial – BMJ
Effects of Colesevelam on Bowel Symptoms, Biomarkers, and Colonic Mucosal gene Expression in Patients with Bile Acid Diarrhea in a Randomized Trial. – CGH
Possible tumour cell reimplantation during curative endoscopic therapy of superficial Barrett’s carcinoma – GUT
Pneumatic dilation for persistent dysphagia after antireflux surgery, a multicentre single-blind randomized sham-controlled clinical trial. – GUT
Efficacy of Therapy for EOE in Real-World Practice – CGH
ACG Clinical Guideline: Management of Irritable Bowel Syndrome – ACG

FYI – if you need me to send you the article, please e-mail me, and I will.

GI Pearls Gastroenterology Podcast Episode 47 - January 2021 Jan 02, 2021

Show notes for Episode 47, January 2021

Endoscopic Recognition and management strategies for Malignant Colorectal Polyps: Recommendation of the US Multi-Society Task force on Colorectal Cancer – GIE
Polyp morphology: an interobserver evaluation for the Paris classification among international experts – AmJ Gastro
Outcomes in lower GI bleeding comparing weekend with weekday admission. – GIE
Efficacy and Safety of Ornithine Phenylacetate for Treating Overt Hepatic Encephalopathy in a Randomized Trial – CGH
A Trial of Ornithine Phenylacetate and the Arc of Ammonia’s History for Overt Hepatic Encephalopathy – CGH
Are Gastrointestinal Symptoms Specific for Coronavirus 2019 Infection? A Prospective Case-Control Study from the United States – Gastro
A randomized trial comparing antibiotics with appendectomy for appendicitis. – NEJM
FIT test after negative colonoscopy may reduce the risk of incident colorectal cancer in a population-based screening programme – GUT
The efficacy and safety of Vitamin C for Iron Supplementation in Adult Patients with Iron Deficiency Anemia – Jama Open
Randomised comparison of postpolypectomy surveillance intervals following a two-round baseline colonoscopy. – GUT
Disease Progression and Outcomes of Pregnancies in Women With Eosinophilic Esophagitis – CGH
Comparing Laparoscopic Elective Sigmoid Resection with Conservative Treatment in improving QoL of Patients with Diverticulitis. – JAMA Surgery

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GI pearls December 2020 Dec 05, 2020

Show notes for Episode 46 for December 2020

Sequential endoscopist-driven phone calls improve capture rate of adverse events after ERCP: a prospective study – GIE
Regular use of proton pump inhibitors and risk of type 2 diabetes: results from three prospective cohort studies – GUT
Long-Term Consequences of Undiagnosed Celiac seropositivity – Am J Gastro
Hyperbaric oxygen therapy is effective in the treatment of inflammatory and fistulizing pouch complications. – CGH
Evaluating the optimum number of biopsies to assess histological inflammation in ulcerative colitis: a retrospective cohort study – Alimentary Pharmacology&Ther
Neutrophil-to-lymphocyte ratio and risk of neoplastic progression in patients with Barrett’s esophagus – Endoscopy
Empirical Treatment With Carbapenem vs Third-generation Cephalosporin for Treatment of Spontaneous Bacterial Peritonitis
Combination Therapy of Adalimumab With an Immunomodulator Is Not More Effective Than Adalimumab Monotherapy in Children With Crohn’s Disease: A Post Hoc Analysis of the PAILOT Randomized Controlled Trial – IBD journal
Treatment of Gut Fermentation Syndrome with FMT – Annals of IM
A Prospective evaluation of POCUS diagnosis of diverticulitis in the emergency Department – Ann Emerg Med 2020
The long-term outcomes and natural disease course of serrated polyposis syndrome: over 10 years of prospective follow-up in a specialized center – GIE

GI Pearls - November 2020 Nov 01, 2020

Show notes for Episode 45 for November 2020

Evaluation of Acute Mountain Sickness by Unsedated Transnasal Esophagogastroduodenoscopy at High Altitude – CGH
Early Colonoscopy Does Not Improve Outcomes of Patients With Lower Gastrointestinal Bleeding: SRM – CGH
Adverse Events After Inpatient Colonoscopy in Octogenarians – J of Clinical Gastro
Comparative Efficacy of Drugs for the Treatment of Chronic Constipation – J of Clinical Gastro
Two vs one forward view examination of right colon on adenoma detection: an international multicenter randomized trial – CGH
Effects of Time-Restricted Eating on Weight Loss and Other Metabolic Parameters in Women and Men With Overweight and Obesity – Jama Internal Medicine
Anti–Siglec-8 Antibody for Eosinophilic Gastritis and Duodenitis – NEJM
Coexistent faecal incontinence and constipation: A cross-sectional study of 4027 adults undergoing specialist assessment – EClinical Medicine
Meta-analysis of Virtual-based Chromoendoscopy Compared With Dye-spraying Chromoendoscopy Standard and High-definition White Light Endoscopy in Patients With Inflammatory Bowel Disease at Increased Risk of Colon Cancer – IBD journal

GI Pearls - October 2020 Oct 05, 2020

Show Notes for October 2020 – Episode 44

A Quarter of Participants With Advanced Neoplasia Have Discordant Results From 2-Sample Fecal Immunochemical Tests for Colorectal Cancer Screening – CGH
Assessment of Clinical Conditions Associated with Splenic Infarction in Adult Patients – JAMA Internal Medicine
Unsedated colonoscopy – impact on quality indicators – Dig Dis Sci
The effect of green kiwifruit on gas transit and tolerance in healthy humans – Neurogastroenterology & Motility
Second international Guidelines for the Diagnosis and Management of HHT – Annals of IM
AGA Clinical Practice Guidelines on the Gastrointestinal Evaluation of Iron Deficiency Anemia – GASTRO
AGA Clinical Practice Guidelines on the Role of Probiotics in the Management of Gastrointestinal Disorders – Gastro
Interview with Jonathan Tsoni Peled, MD/PhD from Memorial Sloan Kettering in NYC. Twitter: @tsonipeled

GI Pearls - September 2020 Sep 10, 2020

Show notes for Episodes 43 – September 2020

Levels of Vitamin D are low after Crohn’s disease is established but not before – CGH
Rapid recurrence of EOE activity after successful treatment in the observational phase of a randomised trial. – CGH
Clinical outcomes of adults with eosinophilic esophagitis with severe stricture. – GIE
Quality of Colonoscopy: A Comparison Between Gastroenterologists and Nongastroenterologists – Dis of colon & Rectum.
A Novel Score to Predict Esophageal Varices in Patients with Compensated Advanced Chronic Liver Disease – DDS
https://cookcountyscore.shinyapps.io/cookcountyscore/
Outcomes of Gallbladder Polyps and Their Association With Gallbladder Cancer in a 20-Year Cohort – JAMA Network
Discordance Between Patient-Reported Outcomes and Mucosal Inflammation in Patients With Mild to Moderate Ulcerative Colitis – CGH
Rifabutin-Based triple therapy for Hpylori Eradication – Annals of IM
Does Gastric Bypass Improve Glycemic Control Beyond the Effect of Weight Loss? – NEJM
Regression of Fibrosis Stage With Treatment Reduces Long-Term Risk of Liver Cancer in Patients w/ Hemochromatosis Caused by Mutation in HFE – CGH

GI Pearls July - 2020 Aug 17, 2020

Show notes for Episodes 42 – July/August 2020

Use of total underwater colonoscopy to navigate endoscopic challenges – CGH
Performance of radiographic imaging after incomplete colonoscopy for non-malignant causes in clinical practice. – GIE
Cognitive Deficit and white matter changes in persons with celiac disease: a population based study. -Gastroenterology
Endoscopic gastric body plication for the treatment of obesity – GIE
Cold snare piecemeal EMR of large sessile colnic polylps >20mm – GIE
AGA clinical Practice Update on Functional Heartburn: Expert Review – Gastro
Imipramine for Treatment of Esophageal Hypersensitivity and Functional Heartburn – Am J Gastro
Superiority of Higher‑Volume Fresh Feces Compared to Lower‑Volume Frozen Feces in Fecal Microbiota Transplantation for Recurrent Cdiff – Dig Dis & Sciences
Practical Tips on TIPS: When and When NOT to request it.
TIPS to the rescue: Preoperative Transjugular Intrahepatic Portosystemic Shunt (TIPS) placement in a patient with caput medusae and colon cancer – Radiology Case Reports
Real-World practice patterns in the Era of Rectal Indomethacin for prophylaxis against Post-ERCP Pancreatitis in a high risk cohort – AmJ Gastro
Delays in colonoscopy start time are associated with reductions in adenoma detection rates – Digest Liver Dis

GI Pearls June - 2020 Jul 06, 2020

Show notes for Episodes 41 – June 2020

Discrepancy between self-reported and actual colonoscopy polypectomy practices for the removal of small polyps – GIE
AGA Guidelines on the management of Moderate to Severe Ulcerative Colitis – Gastro
Resistance training increases muscle strength and muscle size in patients with liver cirrhosis. – CGH
Reduced incidence of Hepatic encephalopathy and higher odds of resolutions associated with eradication of HCV – CGH
Ammonia Levels do not guide clinical management of patients with hepatic encephalopathy caused by cirrhosis. – Am J Gastro
Low-Value Levels: Ammonia Testing Does not Improve the Outcomes of HE. – Am J Gastro
Young adults and metachronous neoplasia: risks for future advanced adenomas and large serrated polyps compared with older adults – GIE
Changing patters in the epidemiology and outcomes of IBD in the UK – 2000-2018 – AP&T
Use of Fecal Occult Blood Testing as a Diagnostic Tool for Clinical Indications: SRMA – Am J Gastro
Low incidence of aerodigestive cancers in patients with negative results from colonoscopies, regardless of findings from stool DNA tests. – CGH
Endoscopic retrieval of magnetic foreign body ingestions with a nasal bridle: description of a novel technique – GIE
Underwater versus conventinal endoscopic resection of nondiminutive nonpedunculated colorectal lesions: RCT – GIE
Cancer Prevention With Aspirin in Hereditary Colorectal Cancer (Lynch Syndrome), 10-year Follow-Up – Lancet
AGA and Allergy Immunology Guidelines for EOE – Gastro

GI Pearls May - 2020 May 16, 2020

Show notes for Episodes 40 – May 2020

Choosing a prokinetic for your patient beyond metoclopramide – AmJ Gastro
Ultraprocessed Food Consumption and Risk of T2DM among participants of the NutriNet-Sante Prospective Cohort – JAMA Int Med
Diagnosis and Treatment of Clostridioides (Clostridium) difficile Infection in Adults in 2020 – JAMA
Clinical importance of cold polypectomy during the insertion phase in the left side of the colon and rectum: multicenter randomized controlled trial (PRESECT study). – GIE
Timing of endoscopy for Acute Upper Gastrointestinal Bleeding – NEJM
Trends in US Burden of C.difficile infection – NEJM
Mechanism, Evaluation and Management of Chronic Constipation – Gastroenterology
Undisclosed payments by pharmaceutical and medical device manufacturers to authors of endoscopy guidelines in the United States – GIE
Managing conflicts of interest in clinical practice guidelines – GIE
Hepatopulmonary Syndrome – NEJM
Reversal of Digital Clubbing After Lung Transplantation in Cystic Fibrosis Patients: A Clue to the Pathogenesis of Clubbing – Pediatr Pulmonol.
Infectious Proctitis – NEJM
Intestinal Lipomatosis – NEJM
EUS-guided gastroenteric anastomosis as a bridge to definitive treatment in benign gastric outlet obstruction – GIE
Uptake of Colorectal Cancer Screening by Physicians Is Associated With Greater Uptake by Their Patients – Gastro
Immunosuppression in Autoimmune Hepatitis: Is There an End Game? – Am J Gastro

GI Pearls March/April- 2020 Apr 01, 2020

Show notes for Episodes 39 – February-March 2020

Prevalence of colorectal cancer and advanced adenoma in patients with acute diverticulitis – GIE
Pancreatic tuberculosis: A systematic review of symptoms, diagnosis and treatment – UEGJournal
Recommendations for Follow-Up After Colonoscopy and Polypectomy: A Consensus Update by the US Multi-Society Task Force on Colorectal Cancer – Gastro
Risk of progression of Barrett’s esophagus indefinite for dysplasia: Meta-analysis – GIE
AGA Clinical Pratice Update – Management of Pancreatic Necrosis – Gastro
Establishing or Exaggerating Causality for the Gut Microbiome: Lessons from Human Microbiota-Associated Rodents – Cell
Neutropenic Enterocolitis: Clinical Features and Outcomes – Dis Colon Rectum.
Long-term Risk of Malignancy in Branch-Duct Intraductal Papillary Mucinous Neoplasms – Gastro
Increased incidence and Mortality of Gastric Cancer in Immigrant Population from High to Low Regions of Incidence: Systematic Review – CGH
AGA: Clinical Practice Guidelines on management of Gastric Intestinal Metaplasia – Gastro

GI Pearls January 2020 Feb 02, 2020

Show notes for Episodes 38 – January 2020

GI Pearls December 2019 Dec 28, 2019

Show Notes for December 2019 – Episode 37

Assessment of Publication Trends of Systematic Reviews and RCTs – JAMA Int Med.
Association between Hpylori exposure and decreased odds of EOE – CGH
Effect of anti-Hpylori therapy on incidence of autoimmune diseases, – CGH
AGA Practice Update on Surveillance for cancer in patients with PSC – Gastro.
Screening for colorectal cancer in asymptomatic average-risk adults: ACP guideline – Annals of Int Med
High intensity versus low intensity surveillance for patients with colorectal adenomas – Annals of Int med
Infliximab-Tumor Necrosis Factor complexes Elicif formation of Anti-Drug Antibodies – Gastro
Outcomes of Patients with IBD switched from maintenance therapy with a biosimilar to Remicade – CGH
Lactose drives Enterococcus expansion to promote graft-versus-host disease – Science
The association between dietary fiber deficiency and high-income lifestyle-associated diseses: Burkitt’s hypothesis revisited.
Compared abilities of endoscopic techniques to increase colon adenoma detection rates – CGH
Advanced imaging for detection and differentiation of colorectal neoplasia:ESGE Guidelines – Endoscopy

GI Pearls November 2019 Nov 24, 2019

Show Notes for November 2019 – Episode 36

Detection of Various Microplastics in Human stool – Annals of int Med
Herpes Zoster in Tofacitinib: Risk is Further Increased with Glucocorticoids but not Methotrexate – Arthritis Care Res
Fatty Liver Disease Caused by High-Alcohol-Producing Klebsiella pneumoniae – Cell
Incidence of and Risk Factors for Hepatic Encephalopathy in a Population-Based Cohort of Americans – Hepatology Communications
FFP transfusion in patients with cirrhosis and coagulopathy: effect on conventional coagulation tests and thrombomodulin-modified thrombin generation – J Hepatol.
Effect of Chromoendoscopy in the proximal colon on Colorectal neoplasia detection in Lynch syndrome: A multicenter randomized controlled trial. – GIE
Terminology, Molecular featuers, Epidemiology, and Management of Serrated Colon neoplaisa.
Providing data for serrated polyp detection rate benchmarks – GIE
Management of Nonvariceal Upper GI bleeding: Guideline recommendations from the International Consensus Group – Ann of Int Med
Efficacy of Prophylactic Hemoclips in prevention of delayed post-polypectomy Bleeding in patients with large colonic polyps – Gastro
Clip Closure Prevents Bleeding After Endoscopic resection of large colon polyps in a randomized trial – Gastro

GI Pearls October 2019 Oct 09, 2019

Show Notes for Oct 2019 – Episode 35

Appropriate therapeutic drug monitoring of Biologic agents for Patients with IBD – CGH
The View from Europe – TDM – CGH
Cold snare vs Heparin bridging and hot snare polypectomy in patients on anticoagulants with subcentimeter polyps. – Annals of int Med.
High-Dose Vitamin D Supplementation on Volumetric Bone Density and Bone Strength – JAMA
Safety of Endoscopy in Heritable Connective Tissue Disorders – Am J Gastro
ASGE guideline on screening and surveillance of Barrett’s esophagus – ASGE
Prucalporide in Gastroparesis: A Randomized Placebo-controlled Crossover Study. – Am J Gastro
Over-Utilization of Repeat Upper Endoscopy in patients with non-dysplastic Barrett’s esophagus – Am J Gastro
Controlling fecal incontinence in women by performing anal exercises with biofeedback or loperamide: a randomized clinical trial. – Lancet Gastro &Hep
Toshihiro Sugiyama Understanding the Current Evidence on Proton Pump Inhibitor Use and Bone Health – Gastro
Ursodeoxycholic acid versus placebo in women with intrahepatic cholestasis of pregnancy (PITCHES):a randomised controlled trial – Lancet’
Effect of Bismuth Subsalicylate vs Placebo on Use of Antibiotics Among Adult Outpatients With Diarrhea in Pakistan: A Randomized Clinical Trial. – JAMA Netw Open
Association between soft drink consumption and mortality in 10 european countries. – JAMA
Validation of Diagnostic and Performance Characteristics of the Wireless Motility Capsule in Patients with Suspected Gastroparesis – CGH
Vedolizumab versus Adalimumab for Moderate-to-Severe Ulcerative Colitis – NEJM
Ustekinumab for Ulcerative Colitis – NEJM

GI Pearls September 2019 Sep 05, 2019

Show Notes for Sept 2019 – Episode 34

Guidelines on management of cyclic vomiting syndrome – Neurogastro and Motility
Drug-induced Acute-on-Chronic Liver Failure in Asian Patients – Am J Gastro
The efficacy of split-dose bowel prep for polyp detection: Meta-analysis – Am J Gastr
Drug-induced liver injury – types and phenotypes – NEJM
ASGE guideline on the role of endoscopy for bleeding from Chronic radiation proctopathy – GIE
Efficacy of budesonide orodispensible tablets as induction therapy for EOE – randomized trial – Gastro
Endoscopic control of polyp burden and expansion of surveillance intervals in serrated polyposis syndrome – GIE
Efficacy of FMT in IBS – Meta Analysis – Am J Gastr
FMT in patients with PSC: Pilot clinical trial – Am J Gastr
Nosocomial infections are frequent and negatively impact outcomes in hospitalized patients – Am J Gastro
High immunogenicity of the PCV13 in immunocompromised adults with IBD – Am J Gastro
Association of US News and World Ranking for GI and GIOperation With Patient Outcomes in Abdominal Procedures- JAMA Surgery
JAMA Clinical Guidelines Synopsis – CRC screening

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