Futures in Biotech (Audio)

FiB 95: So Long and Thanks for All the FiBs Jul 06, 2012

We bring back all the co-hosts, panelists, and subject matter experts for a touchy feeling - warm and fuzzy feel good farewell. FiB is moving to: Microbe TV

Host: Marc Pelletier

Guests: George Farr, Ph.D., Mark Griswold, Jasen Buch, Vincent Racaniello, Ph.D, Andre Nantel, Ph.D, David Thomas, Justin Sanchez, Ph.D, and Dave Brodbeck, Ph.D

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 94: Getting DNA Right-s Jun 08, 2012

We navigate the waters of Biotechnology. Gene patents, how do you get them and why are they there? And once you have them, how are you going to finance your company and move forward?

Eileen Smith Ewing is a shareholder of GreenbergTraurig, Boston, MA; Chair, Committee on Biotechnology; & Chair, Life Sciences Division, American Bar Association

Hosts: Marc Pelletier and Denise Howell

Guest: Eileen Smith Ewing

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 93: Snyder's Omics Apr 06, 2012

The technologies that our guest has developed are playing an important role in changing the world, not like the car, the microwave and the cell phone, but as in Drs. Flox, McCoy, and Crusher.

Host: Marc Pelletier

Co-Host: Andre Nantel, Ph.D

Guest: Dr. Michael Snyder

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 92: Foldit - Crowd Sourcing God's Work Mar 09, 2012

Dr. David Baker explains how the game Foldit uses crowdsourcing to intelligently design artificial proteins never seen before in nature.

Host: Marc Pelletier

Co-Host: Markus Veolter

Guest: Dr. David Baker

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 91: 6 PhDs Piled High and Deep Dec 16, 2011

In this episode of Futures in Biotech, we talk about the Frontiers of Biotechnology - where the line between science and sci-fi are beginning to blur.

Host: Marc Pelletier

Guests: George Farr, Ph.D., Mark Gerstein, David Thomas, Justin Sanchez, Ph.D, and Simon Melov, PhD

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 90: In-Silico Models of Organ Morphogenesis Dec 02, 2011

In this episode of Futures in Biotech, Dr. Celeste Nelson, from Princeton University, explores the fundamental mechanisms of organ morphogenesis.

Host: Marc Pelletier

Co-Host: Andre Nantel, Ph.D

Guest: Dr. Celeste Nelson, Ph.D.

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

Sponsor:

Ford Technology

FiB 89: Towards Curing Malaria With Dr. Elizabeth Winzeler Nov 18, 2011

Dr. Elizabeth Winzeler describes her approaches to drug discovery in an effort to tackle Malaria.

Host: Marc Pelletier

Guest: Dr. Elizabeth Winzeler, Ph.D.

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

Sponsor:

Ford

FiB 88: Cogito, Ergo Sum... Multitasking? Nov 04, 2011

How understanding our mind will shape our futures with Dr. Adam Gazzaley.

Host: Marc Pelletier

Co-Host: Dave Brodbeck, Ph.D

Guest: Adam Gazzaley

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

Sponsor:

Ford

FiB 87: Anti-Matter Message in a Magnetic Bottle Sep 30, 2011

We talk with Jeffrey Hangst about the successful trapping of anti-hydrogen to hopefully answer some of our most important questions about the universe.

Host: Marc Pelletier

Guest: Jeffrey Hangst

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 86: Biomasses for the Masses Sep 09, 2011

Changing an Amish farm in Ohio into an energy source solution for modern times.

Host: Marc Pelletier

Guests: Jon Griswold, Matthew J. Griswold, CFA, and Mark Griswold

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 85: Modeling Life With the World's Most Powerful Computer System Aug 19, 2011

Dr. Vijay Pande, Stanford's Director of Folding@Home, details how the world's most powerful system models Alzheimer's and other human diseases.

Host: Marc Pelletier

Guest: Vijay S. Pande

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 84: Biotech - Hot in Cleveland Jul 15, 2011

Baiju Shah, President & CEO of BioEnterprise, explains how to transform a regional economy into a thriving biotechnological innovation center.

Host: Marc Pelletier

Guest: Baiju Shah, J.D.

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 83: Bioinformatics: Essential Gene Names Skewed in a Network of Blame Jul 08, 2011

Dr. Mark Gerstein from Yale University explains the essence of life through network theory.

Here you can find an important podcast: Biological Network Analysis

Host: Marc Pelletier

Guest: Mark Gerstein

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 82: Bionic Brain Symbionts: The Next Phage of Human Slurry Jun 24, 2011

We discuss everything from symbiotic devices to human proteome phage to the race between transcription and translation, genetics gone wild.

Host: Marc Pelletier

Guests: Andre Nantel, Ph.D and Justin Sanchez, Ph.D

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 81: Worm Research: The Buck Starts Here Jun 17, 2011

Dr. Gordon Lithgow bridges the science of protein folding and life extension.

Host: Marc Pelletier

Co-Host: Simon Melov, PhD

Guest: Gordon Lithgow, Ph.D.

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 80: Light Up the Brain May 20, 2011

Using optogenetics to study learning and cognition.

Host: Marc Pelletier

Co-Host: Dave Brodbeck, Ph.D

Guest: Dr. Ann M. Graybiel

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 79: Oceans 20 May 13, 2011

The Test Run, the technology that will transition us into the next era of medicine.

Host: Marc Pelletier

Co-Host: Mark Gerstein

Guest: Dr. Tommy Nilsson

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 78: TWiV Infects FiB Mar 18, 2011

It's a science mashup. FiB and TWiV together for one big show.

Hosts: Marc Pelletier and Vincent Racaniello, Ph.D

Guests: Dickson D. Despommier, Ph.D., Alan Dove, Ph.D, and Richard Condit, Ph.D

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 77: How The Environment and A Single Protein Influence Evolution Mar 11, 2011

How the environment and a single protein influence evolution.

Host: Marc Pelletier

Guests: Dr. Susan Lindquist and Daniel Jarosz, Ph.D.

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 76: It's Time To Proteo Me Feb 25, 2011

How mass spectrometry has become one of the most important technologies in our move toward personalized medicine.

Hosts: Marc Pelletier and Vincent Racaniello, Ph.D

Guest: Ruedi Aebersold

Sponsored by: Synergy 1.

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 75: It's Time To Start the Human Proteome Feb 18, 2011

The move to the Human Proteome is the next big transition in modern medicine.

Host: Marc Pelletier

Guests: Dr. John Bergeron and Dr. Tommy Nilsson

Sponsored by: Synergy 1.

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 74: Cancer and Aging: Rival Demons with Dr. Judith Campisi Jan 14, 2011

Dr. Judith Campisi's scientific investigations are at the nexus between cancer and aging. She seeks to better understand how cellular senescence contributes to the pathophysiology of aging.

Host: Marc Pelletier

Guests: Simon Melov, PhD and Dr. Judith Campisi, Ph.D.

Sponsored by: Synergy 1.

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 73: The New Science of Aging Dec 17, 2010

We will discuss the biotech of life extension with the scientist that discovered the Sirtuan family of genes.

Host: Marc Pelletier

Guest: Simon Melov, PhD

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 72: A Four Billion Year Old Social Network Dec 10, 2010

How controlling bacterial behavior may lead to a new class of urgently needed antibiotics.

Host: Marc Pelletier

Guest: Dr. Bonnie Bassler

Sponsored by: Synergy 1.

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 71: Genomics, Proteomics, Cellular Immunity, and Anti-Matter Nov 19, 2010

The '1000 Genome Project', 'Billion Dollar Human Proteome', viral killing proteins, and capturing anti-matter.

Hosts: Marc Pelletier, Vincent Racaniello, Ph.D, and Andre Nantel, Ph.D

Co-Host: George Farr, Ph.D.

Guest: Mark Gerstein

Sponsored by: Synergy 1.

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 70: SBIR Funding: The Business of Science Nov 05, 2010

How to fund the development of your own technology through SBIR funding.

Host: Marc Pelletier

Guest: Lisa Kurek

For a free audiobook, visit Audible.com/biotech.

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 69: The Power of Yeast Genetics Oct 15, 2010

Looking at one of the most powerful genetic model systems, Saccharomyces cerevisiae, with Malcolm Whiteway, Ph.D NRC-CNRC Group leader for Biotechnology Research institute, National Research Council of Canada, Montreal.

Hosts: Marc Pelletier and Vincent Racaniello, Ph.D

Guest: Malcolm Whiteway, Ph.D

For a free audiobook, visit Audible.com/biotech.

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 68: Rats Will Inherit the Earth Oct 01, 2010

How studying mammalian biological history can help us better understand ourselves.

Host: Marc Pelletier

Guest: Darin Croft, Ph.D

For a free audiobook, visit Audible.com/biotech.

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 67: Triceratopping Egg Mountain Sep 17, 2010

Dinosaur hunting with the man who inspired Jurassic Park, Dr. Jack Horner, curator of Paleontology at the Museum of the Rockies and Montana State University Regents' Professor of Paleontology.

Host: Marc Pelletier

Guest: Dr. Jack Horner

For a free audiobook, visit Audible.com/biotech.

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 66: The Homebrew Genomics Club Sep 10, 2010

A first hand account on the genesis of the Human Genome Project with our guest, Dr. David Botstein, Director of the Lewis-Sigler Institute for Integrative Genomics at Princeton University.

Hosts: Marc Pelletier and Andre Nantel, Ph.D

Guest: Dr. David Botstein

For a free audiobook, visit Audible.com/biotech.

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 65: Tackling Genetic Disease Aug 27, 2010

Progress in molecular biology and the latest strategies for tackling genetic disease.

Our guest is David Thomas, professor and chair, Department of Biochemistry, McGill University; Canada Research Chair in Molecular Genetics.

Hosts: Marc Pelletier and Dave Brodbeck, Ph.D

Guest: David Thomas

For a free audiobook, visit Audible.com/biotech.

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 64: The Future Is Viral Jul 23, 2010

Five scientists, George Farr, Mark Griswold, Dave Brodbeck, Vincent Racaniello and David Thomas, discuss their hopes and aspirations for biotechnology in a post-genomics era.

Host: Marc Pelletier

Guests: George Farr, Ph.D., Mark Griswold, Dave Brodbeck, Ph.D, Vincent Racaniello, Ph.D, and David Thomas

For a free audiobook, visit Audible.com/biotech.

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 63: How to Use a Mouse Jul 02, 2010

Nobel Laureate Dr. Mario Capecchi teaches us how to use a mouse to dissect the human genome and understand disease.

Our guest is Mario Capecchi, Ph.D., distinguished Professor of Human Genetics and Biology at the University of Utah and investigator with the Howard Hughes Medical Institute

Host: Marc Pelletier

Guest: Mario Capecchi, Ph.D.

For a free audiobook, visit Audible.com/biotech.

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 62: X-Ray Crystallography Jun 25, 2010

Dr. Alexander McPherson explains X-ray crystallography, a technique that will produce a true atomic anatomy of the human body.

Books referenced in this episode: Crystallization of Biological Macromolecules, COLD SPRING HARBOR LABS. Introduction to Macromolecular Crystallography, WILEY BLACKWELL.

Host: Marc Pelletier

Co-Host: George Farr, Ph.D.

Guest: Dr. Alexander McPherson

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 61: One Heart Beat Away Jun 15, 2010

Tackling problems of the heart with biotechnology.

Our guest is Julian Stelzer, Assistant Professor of Physiology and Biophysics, Case Western Reserve University

Host: Marc Pelletier

Guest: Julian E. Stelzer, PhD

For a free audiobook, visit Audible.com/biotech.

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 60: Do You Come to This Cave Often? May 21, 2010

Primate face recognition, new cure for HVC, genetic base change, neanderthals and humans, and more.

Host: Marc Pelletier

Guests: Dave Brodbeck, Ph.D, Andre Nantel, Ph.D, Vincent Racaniello, Ph.D, and George Farr, Ph.D.

For a free audiobook, visit Audible.com/biotech.

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 59: No Room for Failure May 10, 2010

A first hand account of the Apollo Missions from the floor of Mission Control from Michael Vucelic, former Apollo system manager for NASA and Rockwell.

Host: Marc Pelletier

Guest: Michael Vucelic

For a free audiobook, visit Audible.com/biotech.

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 58: Vertical Farms and Much, Much More With Dick Despommier Apr 16, 2010

Feeding the world with indoor vertical farming.

Our guest is Dickson D. Despommier, Ph.D., Professor of Microbiology, College of Physicians and Surgeons, Columbia University, New York, NY. Host of This Week in Virology; Host of This Week in Parasitism.

Hosts: Marc Pelletier and Vincent Racaniello, Ph.D

Guest: Dickson D. Despommier, Ph.D.

For a free audiobook, visit Audible.com/biotech.

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 57: Mechanisms of Non-Mendelian Inheritance in Evolution Apr 02, 2010

How prion proteins can act in non-mendelian inheritance, or evolution without DNA.

Our guests are Susan Lindquist, Ph.D., professor of biology at MIT and investigator of the Howard Hughes Medical Institute, Simon Alberti, group leader at the Max Planck Institute of Molecular Cell Biology and Genetics, and Randal Halfmann, a grad student in Dr. Lindquist's lab at MIT

Host: Marc Pelletier

Co-Host: George Farr, Ph.D.

Guests: Dr. Susan Lindquist and Simon Alberti

For a free audiobook, visit Audible.com/biotech.

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 56: New Antiviral Strategies with Karla Kirkegaard Mar 19, 2010

A look into RNA viruses and more with Dr. Karla Kirkegaard, professor and chair of the Department of Microbiology and Immunology at the Stanford University School of Medicine.

Hosts: Marc Pelletier and Vincent Racaniello, Ph.D

Guest: Dr. Karla Kirkegaard

For a free audiobook, visit Audible.com/biotech.

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 55: Ultra Low Power Bioelectronics, Part 2 Feb 26, 2010

Dr. Rahul Sarpeshkar, Ph.D., associate professor, of electrical engineering and computer science at the Massachusetts Institute of Technology, talks about how to improve electronic systems using biologically inspired design.

Host: Marc Pelletier

Guests: Justin Sanchez, Ph.D and Rahul Sarpeshkar, Ph.D.

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 54: Personal Genome Project - Leo's Genome? Feb 23, 2010

The Personal Genome Project: making personal genome sequencing more affordable, accessible, and useful.

Our guest is Dr. George Church, Professor of Genetics at Harvard Medical School and Director of the Center for Computational Genetics.

Hosts: Marc Pelletier and Leo Laporte

Guest: Dr. George Church

For a free audiobook, visit Audible.com/biotech.

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 53: Project Genome 10K - Mapping Life's Greatest Journey Jan 26, 2010

Project Genome 10k, and how sequencing ten thousand vertebrate genomes will tell us about our past, present, and future.

Our guest is Dr. David Haussler, professor of biomolecular engineering, University of California at Santa Cruz, director of the Center for Biomolecular Science & Engineering, and investigator at the Howard Hughes Medical Institute

Host: Marc Pelletier

Guest: Dr. David Haussler

For a free audiobook, visit Audible.com/biotech.

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 52: Ultra Low Power Bioelectronics, Part 1 Dec 25, 2009

Bio-inspired and biomedical electronics, circuit modeling of biology, and more.

Our guest is Rahul Sarpeshkar, Ph.D., associate professor of electrical engineering and computer science at the Massachusetts Institute of Technology and author of Ultra Low Power Bioelectronics: Fundamentals, Biomedical Applications, and Bio-inspired Systems

Host: Marc Pelletier

Guests: Justin Sanchez, Ph.D, Mark Griswold, and Rahul Sarpeshkar, Ph.D.

For a free audiobook, visit Audible.com/biotech.

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 51: MRI Engineering Made Easy Dec 18, 2009

How to build an MRI, and how it works.

Host: Marc Pelletier

Guest: Mark Griswold

For a free audiobook, visit Audible.com/biotech.

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 50: More Biotech Stories Dec 08, 2009

Marc and some the FiB regulars cover important stories in the biotechnology realm.

Host: Marc Pelletier

Guests: George Farr, Ph.D., Dave Brodbeck, Ph.D, Justin Sanchez, Ph.D, and Vincent Racaniello, Ph.D

For a free audiobook, visit Audible.com/biotech.

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 49: Brain-Machine Interfaces Nov 17, 2009

Dr. Justin Sanchez, Assistant Professor of Pediatrics, Neuroscience, and Biomedical Engineering, and Biomedical Engineering at the University of Florida, walks us through the technology of brain machine interfaces.

Hosts: Marc Pelletier and Dr. Kiki Sanford

Guest: Justin Sanchez, Ph.D

For a free audiobook, visit Audible.com/biotech.

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 48: Sequencing an Ocean's Genome Nov 02, 2009

Dr. Delong discusses the use of metagenomics to understand microbial life in the Pacific Ocean.

Hosts: Marc Pelletier and Andre Nantel, Ph.D

Guest: Edward Delong, Ph.D.

For a free audiobook, visit Audible.com/biotech.

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 47: Genetic Engineering in the 21st Century Sep 28, 2009

Dr. Oliver Smithies discusses the present and future of genetic engineering

Host: Marc Pelletier

Guests: Andre Nantel, Ph.D and Dr. Oliver Smithies

For a free audiobook, visit Audible.com/biotech.

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 46: Towards Computers That Think Sep 08, 2009

An interview with Dr. Terrence Sejnowski about theoretical and computational biology and neurobiology.

Audible pick: This Is Your Brain on Music: The Science of a Human Obsession, Abridged, By Daniel J. Levitin, Narrated by Edward Herrman. For a free audiobook, visit Audible.com/biotech.

Hosts: Marc Pelletier and Dave Brodbeck, Ph.D

Guest: Terrence Sejnowski

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 45: How To Make A Mouse Jul 26, 2009

Marc talks with Dr. Oliver Smithies, Professor, Department of Pathology and Lab Medicine University of North Carolina at Chapel Hill, 2007 Nobel Laureate, and father of mammalian genetic engineering.

Host: Marc Pelletier

Guest: Dr. Oliver Smithies

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 44: Cogito Ergo Sum by fMRI Jun 29, 2009

Our guest is John Gabrieli; Grover Herman Professor of Health Sciences and Technology and Professor of Brain and Cognitive Sciences, Massachusetts Institute of Technology (MIT)

Looking directly into the human mind with fMRI technology.

Audible pick: Meditations on First Philosophy: With Selections from the Objections and Repiles, Unabridged, By Rene Descartes, Narrated by Paul Hecht. For a free audiobook, visit Audible.com/biotech.

Host: Marc Pelletier

Guests: Dave Brodbeck, Ph.D and John Gabrieli

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 43: Temporal Alien Mammoth Overlords May 31, 2009

From wooly mammoths, to cybernetics, and controlling your computer with your brain, a panel discusses the recent big stories in bioscience.

Host: Marc Pelletier

Guests: Vincent Racaniello, Ph.D, Andre Nantel, Ph.D, Justin Sanchez, Ph.D, and Dave Brodbeck, Ph.D

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 42: Sneezing Pandaemic May 04, 2009

Our guest is Dr. Vincent Racaniello, Ph.D., is a professor of Microbiology at Columbia University Medical Center and the host of This Week in Virology.

Host: Marc Pelletier

Guest: Vincent Racaniello, Ph.D

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 41: Modeling Life With The World's Fastest Computer Apr 30, 2009

A follow-up look at Folding@Home, the world's most powerful distributed computing cluster, designed to perform computationally intensive protein folding simulations.

Our guest is Dr. Vijay S. Pande, Director of Folding@Home and Associate Professor of Chemistry and of Structural Biology, Stanford University

Audible pick: Always Looking Up: The Adventures of an Incurable Optimist, Abridged, By Michael J. Fox, Narrated by Michael J. Fox. For a free audiobook, visit Audible.com/biotech.

Hosts: Marc Pelletier and Randal Schwartz

Guest: Vijay S. Pande

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 40: Virus Reborn Mar 31, 2009

Leading virologist Peter Palese explains why he revived a virus that killed 50 million people.

Our guest is Peter Palese, professor and chair of microbiology at the Mount Sinai School of Medicine in New York.

In the winter of 1918-19, fifty million people died horrible deaths from the Spanish flu. The threat of this happening again today is ever so present. And while we have drugs that are fairly effective against influenza, they are not foolproof.

The possible devastation to humanity from this threat is extremely significant. The world will look to the best and brightest scientists and clinicians in hopes that they know and understand the virus well enough to fight it.

Dr. Palese has made great contributions to our understanding of influenza, and his scientific endeavors have given us the knowledge and tools to prevent this potential devastation.

Hosts: Marc Pelletier and Vincent Racaniello, Ph.D

Guest: Peter Palese

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 39: Food, Genetically Modified Feb 24, 2009

Dr. Lisa Weasel discusses the controversies surrounding genetically-modified foods.

Our guest is Dr. Lisa Weasel, associate professor of biology at Portland State University in Oregon, a member of Governor Ted Kulongoski's task force on developing public policy for bio-pharmaceutical crops in Oregon, and author of Food Fray: Inside the Controversy over Genetically Modified Foods.

Why isn't there a wide consumer acceptance of genetically modified (GM) foods? If we can design crops that reduce pesticides, grow more effectively in poor soil, bring nutrients such as vitamins A to populations with high incidences of blindness, or even just taste better, why are we hesitating?

Audible pick: On the Origin of Species, Abridged, By Charles Darwin, Narrated by Richard Dawkins. To sign up for a free audiobook, visit Audible.com/biotech.

Host: Marc Pelletier

Guest: Dr. Lisa Weasel

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 38: It Is Easy Being Green Jan 31, 2009

How Dr. Martin Chalfie transformed a green fluorescent jellyfish protein into the most important biological marker used today.

Our guest is Dr. Martin Chalfie; Professor and Chair of the Department of Biological Sciences, Colombia University, New York, NY.

This is Part II of our conversation with Dr. Martin Chalfie. In this episode Dr. Chalfie shares the historical account of his contribution to the 2008 Nobel Prize in Chemistry: How he transformed a green fluorescent jellyfish protein into the most important biological marker used today, one that allows us to track the life of recombinant protein in a living cell.

Audible pick: The Ten Most Beautiful Experiments, by George Johnson, Narrated by dion Graham. To sign up for a free audiobook, visit Audible.com/biotech.

Hosts: Marc Pelletier and Dr. Glen Ernstrom

Guest: Martin Chalfie

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 37: Just A Touch Of Green Dec 29, 2008

Our guest is Marty Chalfie, 2008 Nobel Laureate in Chemistry

This episode covers how Marty Chalfie discovered the molecular machinery that senses touch. In Part II, Chalfie describes how he developed one of the most important tools of modern molecular biology, one that allows us to see inside a living cells, down to the protein level. With green fluorescent protein, or GFP, we can now track the life of a protein, from when the gene that makes the protein is turned on, to where it goes, to where it dies.

Audible Pick: The Snows of Kilimanjaro and Other Stories, Abridged, By Ernest Hemingway, Narrated by Stacy Keach.

Hosts: Marc Pelletier and Dr. Glen Ernstrom

Guest: Martin Chalfie

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 36: Avoiding Death, Not Taxes with Dr. Cynthia Kenyon Nov 24, 2008

Our guest is Dr. Cynthia Kenyon; Professor, Department of Biochemistry and Biophysics, University of California San Francisco, Director of the Larry L. Hillblom Center for the Biology of Aging.

We are back into a world leading lab to discuss the genetics of aging. Can it be controlled? You bet, and the implications are enormous. When these findings translate to the clinic, it will truly be a game changer for humanity.

Some interesting links:
sirtrispharma
Elixir
Sirtris

Audible Pick: Prey by Michael Crichton.

Host: Marc Pelletier

Guest: Dr. Cynthia Kenyon

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 35: The Brain Machine Interface Oct 28, 2008

Dr. Justin Sanchez discusses technologies that enable direct brain to computer interfacing, just think...

Dr. Justin C. Sanchez is Director of the Neuroprosthetics Research Group, Assistant Professor, Department of Pediatrics, Division of Neurology, Department of Neuroscience, Department of Biomedical Engineering, University of Florida.

I really had no idea that the technologies that Justin has developed existed other than in science fiction. The possibilities are endless, and could change everything from computing, to flying planes, to simply changing the channel... I will keep these notes short, and let Justin explain.

Find more, including videos at: The Neuroprosthetics Research Group

Host: Marc Pelletier

Guest: Justin Sanchez, Ph.D

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 34: A Great Historical Document - The Human Genome Sep 12, 2008

Mark Gerstein endeavors to make sense our genome on its past and present course.

Our guest is Mark Gerstein, the Albert L. Williams Professor of Biomedical Informatics, a professor of Molecular Biophysics and Biochemistry and professor of Computer Science at Yale University Gerstein Lab.

In past shows, we've had Lee hood, the inventor of the DNA sequencer, and George Church who was among those personally involved in initiating the Human project. But getting the code and really understanding these human blueprints are entirely different problems. Our guest today, Mark Gerstein, is trying to make sense of it all, and his work amoung other things has revealed that the genome is more than just a blueprint, or list of parts, but a rich historical text about our past.

BLAST this sequence: atgttcc tgtccttccc caccaccaag acctacttcc cgcacttcga cctgagccac ggctctgccc aggttaaggg ccacggcaag aaggtggccg acgcgctgac caacgccgtg gcgcacgtgg acgacatgcc caacgcgctg tccgccctga gcgacctgca cgcgcacaag cttcgggtgg acccggtcaa cttcaagctc ctaa

Instructions: Copy and Paste the DNA sequence into the query window, and hit the blast button. What does this encode? Interesting: Try again selecting the NON-HUMAN database. What organism is the exact same gene found in? Why?

Audible pick of the week: Legacy of Ashes: The History of the CIA, Unabridged, By Tim Weiner, Narrated by Stefan Rudnicki. For your free audio book visit Audible.com/biotech.

TWiT T-Shirts from Lori LeBeau Walsh.

Host: Marc Pelletier

Guest: Mark Gerstein

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 33: Dr. Milner's Explorations Into The Human Mind Jul 23, 2008

Dr. Brenda Milner describes the experiments that led to a revolution in modern neuroscience.

Our guest is Dr. Brenda Milner; Dorothy J. Killam Professor of Psychology, Montreal Neurological Institute and Department of Neurology and Neurosurgery, McGill University, Montreal, Quebec, Canada.

Audible pick of the week: Starswarm by Dr. Jerry Pournelle, narrated by Lloyd James. For your free audio book visit Audible.com/biotech.

Host: Marc Pelletier

Guest: Dr. Brenda Milner

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 32: Controlling HIV Evolution Jun 04, 2008

Dr. Ronald Collman, professor of medicine in microbiology, virus/cell/molecular core director, Penn Center for AIDS Research, University of Pennsylvania.

Host: Marc Pelletier

Guest: Dr. Ronald Collman

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 31: The Eensy-Weensy Teenie Weenie Big Bang Apr 23, 2008

Dr. Michio Kaku, Henry Semat Professor of Theoretical Physics at the Graduate Center of the City University of New York and co-founder of String Field Theory.

Host: Marc Pelletier

Guest: Dr. Michio Kaku

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 30: Aubrey de Grey on the Thousand Year Lifespan Mar 26, 2008

A discussion with Aubrey de Grey; Chairman and Chief Science Officer, the Methuselah Foundation.

Host: Marc Pelletier

Guest: Aubrey de Grey

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 29: From Human Genome Project to Your Genome Project (Part II) Feb 06, 2008

Dr. George Church is the Professor of Genetics and Director of the Center for Computational Genetics at Harvard Medical School and Founder & Principle Investigator of The Personal Genome Project.

Dr. Church describes both the underlying DNA technologies and societal implications of personal genomics.

This episode of Futures in Biotech was sponsored by Invitrogen. Save 15% on selected High Fidelity PCR enzymes with the purchase of a Zero Blunt TOPO cloning kit, and other selected TOPO kits. See TOPO ZeroBackground high fidelity. Quote RTPCWU for US or RTPCWC for Canada when ordering.

Host: Marc Pelletier

Guest: Dr. George Church

Thanks to CacheFly for providing the bandwidth for this netcast.

Also thanks to Will Hall for the great opening and closing themes!

FiB 28: One of the Greatest Quests in the World of Genetics Jan 26, 2008

Dr. Richard Lifton describes his scientific journey, which has changed how doctors treat hypertension: a condition that affects approximately one billion people worldwide...

Host: Marc Pelletier

Guest: Dr. Richard Lifton

Thanks to CacheFly for providing the bandwidth for this netcast.

Also thanks to Will Hall for the great opening and closing themes AND Matthew McInerney for the cool FiB Desktops.

FiB 27: Folding@Home at 1.3 Petaflops Dec 28, 2007

Steve Gibson joins me in interviewing a true visionary of biotechnology: Dr. Vijay Pande. Dr. Pande is the creator and Director of Folding@Home, the world's largest distributed computing project (Stanford University) that seeks to address some of the most difficult problems in biology.

It is indeed a pretty amazing story: Sony PS3s are the largest component of the world's fastest computer, running approximately 3x faster than IBM's Blue Gene/L. And, the largest computations are being performed to simulate biology at the atomic level...

Join Leo's folding team!!! Leo's Team

Links: Folding@Home Science Stats

Host: Marc Pelletier

Co-Host: Steve Gibson

Guest: Vijay S. Pande

This episode of Futures in Biotech was sponsored by Invitrogen. Save 15% on selected High Fidelity PCR enzymes with the purchase of a Zero Blunt TOPO cloning kit, and other selected TOPO kits. See TOPO ZeroBackground high fidelity. Quote RTPCWU for US or RTPCWC for Canada when ordering.

Thanks to CacheFly for providing the bandwidth for this netcast.

Also, thanks to Philippe Pelletier and Will Hall for the great opening and closing themes.

FiB 26: The Last Man to Walk on the Moon Nov 21, 2007

Former Senator from New Mexico, Dr. Harrison "Jack" Schmitt, shares his experience of living and working on the moon, the future of space settlements, and solving the worlds energy needs.

Host: Marc Pelletier

Guest: Dr. Harrison "Jack" Schmitt

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 25: From the Human Genome Project to Space Exploration with Dr. George Church (Part I) Oct 03, 2007

Our guest is Dr. George Church, Professor of Genetics and Director of the Center for Computational Genetics, Harvard Medical School, Cambridge, MA.

Dr. George Church explores the fantastic world of genetics from the Earth to Mars!

This episode of Futures in Biotech was sponsored by Invitrogen. Save 15% on selected High Fidelity PCR enzymes with the purchase of a Zero Blunt TOPO cloning kit, and other selected TOPO kits. See TOPO ZeroBackground high fidelity. Quote RTPCWU for US or RTPCWC for Canada when ordering.

Host: Marc Pelletier

Guest: Dr. George Church

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 24: The Phoenix Mars Mission with Dr. Deborah Bass Sep 19, 2007

Our guest is Dr. Deborah Bass, Deputy Project Scientist, Phoenix Mars Mission

Dr. Bass and her colleagues at NASA explore the Martian arctic for signs of life

This episode of Futures in Biotech was sponsored by Invitrogen. Save 15% on the newest Gateway Entry Vectors Invitrogen.com/Gatewayspecial

Host: Marc Pelletier

Guest: Dr. Deborah Bass

Thanks to Phil Pelletier and Will Hall for the great themes.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 23: From Gemini to Mars with Dr. Buzz Aldrin Sep 11, 2007

Dr. Buzz Aldrin talks about Gemini 12, Apollo 11, and the future of space exploration.

Host: Marc Pelletier

Guest: Dr. Buzz Aldrin

This episode of Futures in Biotech was sponsored by Invitrogen. For details on their Topo Cloning Technology visit Invitrogen.com/Topo

Thanks to CacheFly for providing the bandwidth for this netcast.

Also thanks to Philippe Pelletier and Will Hall for the great opening and closing themes.

FiB 22: The Marathon Mouse Sep 01, 2007

Our guest is Dr. Ron Evans, Professor and the March of Dimes Chair in Molecular and Developmental Biology, Salk Institute.

Dr. Ron Evans discusses the genetic engineering of metabolism and the creation of a strain of super mice: the Marathon Mouse

Our two books of the week are My Life with the Chimpanzees by Jane Goodall AND The Genome War: How Craig Venter Tried to Capture the Code of Life and Save the World by James Shreeve. For your free audio book visit Audible.com/Biotech.

Host: Marc Pelletier

Guest: Dr. Ron Evans

Thanks to CacheFly for providing the bandwidth for this netcast.

Also thanks to Philippe Pelletier and Will Hall for the great opening and closing themes AND

FiB 21: Science Versus Cancer with Dr. Evangelos Michelakis Aug 21, 2007

Dr. Evangelos Michelakis, MD, FACC, FAHA explains how to target the metabolism of cancer cells...

Our book of the week, reviewed by Dr. Ginger Campbell from the Brain Science Podcast, is A Short History of Nearly Everything by Bill Bryson. For your free audio book visit Audible.com/Biotech.

Host: Marc Pelletier

Guest: Dr. Evangelos Michelakis

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 20: Dr. Eric Kandel's Insights into the Science of Mind Aug 03, 2007

Dr. Kandel is a Professor of Physiology and Psychiatry and the founding director of the Center for Neurobiology and Behavior of the Columbia University College of Physicians and Surgeons. He was awarded the Nobel Prize in Physiology or Medicine in 2000 for his work on the biological mechanisms for memory. In this episode, he explains how the mind learns and stores memory, and also shares some of his most recent findings.

Host: Marc Pelletier

Guest: Eric R. Kandel

Our book of the week is The Fabric of the Cosmos by Brian Greene. For your free audio book visit Audible.com/Biotech.

Thanks to CacheFly for providing the bandwidth for this netcast.

Also thanks to Philippe Pelletier and Will Hall for the great opening and closing themes AND Matthew McInerney for the cool FiB Desktops.

FiB 19: The Supra Human Organism Jul 18, 2007

Dr. Jeffrey Gordon is a Professor of Gastroenterology, the Director of the Center for Genome Sciences, and the Head of the Department of Molecular Biology and Pharmacology at Washington University in St-Louis. He is also leading one of the most interesting and important metagenomics projects today, the Human Microbiome.

Host: Marc Pelletier

Guest: Jeffrey Gordon, MD

This podcast is brought to you by Audible.com. Download a free audiobook of your choice today at Audible.com/Biotech

Thanks to CacheFly for providing the bandwidth for this netcast.

Also thanks to Philippe Pelletier and Will Hall for the great opening and closing themes AND Matthew McInerney for the cool FiB Desktops.

FiB 18: NanoBiotech Jul 04, 2007

Peter Searson, Director of the Institute for NanoBiotechnology and Professor in the Department of Materials Science and Engineering at Johns Hopkins University, and Denis Wirtz, Associate Director of the Institute for NanoBiotechnology, Professor of Chemical and Biomolecular Engineering, and Professor of Materials Science and Engineering discuss how the intersection between biotech and nanotech promises some amazing applications.

Host: Marc Pelletier

Guests: Peter Searson and Denis Wirtz

This podcast is brought to you by Audible.com. Download a free audiobook of your choice today at Audible.com/biotech

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 17: Biotech Singularity Jun 23, 2007

Our panelists for this episode are Dr. John Bergeron, Professor and Chair of the Department of Anatomy and Cell Biology at McGill University, Dr. Drew Endy, Cabot Assistant Professor of Biological Engineering at MIT, Dr. Edward Delong, Professor, Division of Biological Engineering & Department of Civil and Environmental Engineering at MIT, and Dr. Lee Hood, President of the Institute for Systems Biology in Seattle, Washington.

Host: Marc Pelletier

Guests: Dr. John Bergeron, Dr. Drew Endy, Edward Delong, Ph.D., and Dr. Lee Hood

This podcast is brought to you by Audible.com. Download a free audiobook of your choice today at Audible.com/TWiT

Thanks to CacheFly for providing the bandwidth for this netcast.

Also thanks to Philippe Pelletier and Will Hall for the great opening and closing themes AND Matthew McInerney for the cool new FiB Desktops

FiB 16: 21st Century Biotech - Systems Biology May 26, 2007

Dr. Lee Hood, President of the Institute for Systems Biology, inventor of the DNA sequencer.

Host: Marc Pelletier

Guest: Dr. Lee Hood

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 15: The SuperNet May 02, 2007

Dr. Larry Smarr, the Director of the California Institute for Telecommunications and Information Technology (CalIT2), discusses the future of computing and the internet...

Host: Marc Pelletier

Guest: Larry Smarr

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 14: Working Towards a Cure for Multiple Sclerosis Mar 24, 2007

Scott Johnson is the President and Founder of the Myelin Repair Foundation, and Dr. Robert Miller is a principal investigator with the MRF, and Professor of Neurosciences at Case Western Reserve University School of Medicine in Cleveland OH.

Scott, Robert, and four more great neuroscientists with the MRF have taken on one the great medical challenges our time -Multiple Sclerosis (MS).

Host: Marc Pelletier

Guests: Scott Johnson (Myelin Repair Foundation) and Robert Miller, PhD

If you would like to make a donation toward curing MS please visit The Myelin Repair Foundation.

Thanks to CacheFly for providing the bandwidth for this netcast.

FiB 12: The Era of Shock and Awe Proteomics Feb 21, 2007

Dr. John J. Bergeron, is Professor and Chair of the Department of Anatomy and Cell Biology at McGill University, and former President of the Human Proteome Organization (HUPO), and founder of Caprion Proteomics. In this episode, he describes how proteomics could revolutionize modern medicine...

Host: Marc Pelletier

Guest: Dr. John Bergeron

Thanks to CacheFly for providing the bandwidth for this podcast.

And also thanks to Philippe Pelletier for the great new opening theme and to Will Hall for the closing theme!!!

FiB 11: Ancient DNA - The Neanderthal Genome Dec 20, 2006

Our guests are Dr. Svante Pääbo, Director of the Department of Genetics at the Max Planck Institute for Evolutionary Anthropology and Dr. Thomas Jarvie, Technical Application Manager at 454 Life Sciences

Dr. Svante Pääbo explains how he isolates the ancient DNA of Neanderthals from museum specimens.

Links:

Host: Marc Pelletier

Guests: Dr. Svante Pääbo and Dr. Thomas Jarvie

Thanks to CacheFly for providing the bandwidth for this podcast.

And also thanks to the band Gunther from Cyclone Records for the permission to use their song Wrecking Ball as a theme for this episode of FiB!

FiB 10: Carla Shatz on the Human Brain Dec 08, 2006

Imagine if there was a computer with a multi-core CPU that could self-assemble? And rather than a 64 bit bandwidth, it was 10,000 bit and had access to several terabytes of ram? And more incredibly, all of this could fit into a TWiT beanie?

Host: Marc Pelletier

Guest: Dr. Carla Shatz

For more details, visit Marc Pelletier's blog at http://futuresinbiotech.blogspot.com/.

Thanks to CacheFly for providing the bandwidth for this podcast.

And also thanks to the band Gunther from Cyclone Records for the permission to use their song Wrecking Ball as a theme for this episode of FiB!

FiB 9: Ed Delong on Metagenomics Nov 22, 2006

Dr. Delong uses advanced genomic techniques to explore marine microbial communities in search of new genes...

Host: Marc Pelletier

Guest: Edward Delong, Ph.D.

Thanks to CacheFly for providing the bandwidth for this podcast.

And also thanks to the band Gunther from Cyclone Records for the permission to use their song Wrecking Ball as a theme for this episode of FiB!

FiB 8: Drew Endy on Synthetic Biology Nov 09, 2006

A look at the the emerging field of Synthetic Biology. According to Dr. Endy, "We're going from looking at the living world as only coming from nature, to a subset of the living world being produced by engineers, who design and build hopefully useful living artifacts according to our specifications" (MITWorld).

Host: Marc Pelletier

Guest: Dr. Drew Endy

For more details, visit Marc Pelletier's blog at http://futuresinbiotech.blogspot.com/.

Thanks to CacheFly for providing the bandwidth for this podcast.

And also thanks to the band Gunther from Cyclone Records for the permission to use their song Wrecking Ball as a theme for this episode of FiB!

FiB 7: Dr. Ronald Desrosiers Oct 18, 2006

We talk with Dr. Ronald Desrosiers of the New England Primate Research Center

Host: Marc Pelletier

Guest: Ronald Desrosiers, Ph.D.

For more details, visit Marc Pelletier's blog at http://futuresinbiotech.blogspot.com/.

Thanks to CacheFly for providing the bandwidth for this podcast, and to Will Hall for our theme.

FiB 6: Dr. Linda Griffith on Tissue Engineering Oct 11, 2006

Dr. Griffith is a leader in the field of tissue engineering: a field that seeks to develop replacement organs and tissues, and also provide an unlimited supply of living human organs for scientists to use to better understand disease and develop new therapies.

For more on Dr. Griffith's work: the The Griffith Lab and Dr. Griffith on Scientific American .

Hosts: Marc Pelletier and Leo Laporte

Guest: Linda G. Griffith, PhD

For more details, visit Marc Pelletier's blog at http://futuresinbiotech.blogspot.com/.

Thanks to CacheFly for providing the bandwidth for this podcast, and to Will Hall for our theme.

FiB 5: Andre Nantel on DNA Microarrays Sep 20, 2006

In this episode, we talk about how microarrays are revolutionizing biomedical sciences. Just ten years ago, all genetic and biochemical experiments were performed on a scale of one to a few genes (DNA) or proteins at a time. Now with the advent of microarrays, hundreds of thousands of DNA or protein samples can be analyzed in parallel experiments (side by side on a chip) in a matter of hours. Where once we could only determine whether or not the expression of a single gene was turned on or off using a technique called northern blotting, the dynamic interplay of an entire genome in response to environmental cues or disease states can be monitored in a single experiment. We are slowly transitioning to a new era of individualized medicine, where preventive or therapeutic approaches will be tailored specifically to each individual.

Hosts: Marc Pelletier and Leo Laporte

Guest: Andre Nantel, Ph.D

For more details, visit Marc Pelletier's blog at http://futuresinbiotech.blogspot.com/.

Thanks to CacheFly for providing the bandwidth for this podcast, and to Will Hall for our theme.

FiB 4: Dr. Marc Vidal, Part 2 Aug 16, 2006

Dr. Vidal is working on the next stage in big biotech. Now that we've mapped the human genome it's time to map the interactome, the human protein-protein interaction network. In this episode we talk about the network of interactions, and how closely it mimics other networks, including social networks.

Hosts: Marc Pelletier and Leo Laporte

Guest: Marc Vidal, Ph.D.

Thanks to CacheFly for providing the bandwidth for this podcast.

FiB 3: Dr. Marc Vidal, Part 1 Aug 10, 2006

Dr. Vidal is working on the next stage in big biotech. Now that we've mapped the human genome it's time to map the interactome, the human protein-protein interaction network. In this episode he gives us the groundwork for understanding his work. Next week, in part two, Dr. Vidal explains how the network of protein interactions resembles human social networks.

Hosts: Marc Pelletier and Leo Laporte

Guest: Marc Vidal, Ph.D.

Thanks to CacheFly for providing the bandwidth for this podcast.

FiB 2: Dr. Leonard P. Guarente on Aging Jul 21, 2006

Why do living things age? What genes influence longevity? Is it possible to extend youthfulness by means of genetic manipulation? What does the aging of a yeast cell have in common with the aging of a human being or a mouse? Dr. Guarente analyzes these tantalizing questions and others in this episode.

Hosts: Marc Pelletier and Leo Laporte

Guest: Dr. Leonard P. Guarente

Thanks to CacheFly for providing the bandwidth for this podcast.

FiB 1: Dr. Susan Lindquist Jun 14, 2006

Dr. Susan Lindquist is a member of the Whitehead Institute for Biomedical Sciences at MIT. Her discoveries in protein folding have lead to paradigm shifts in modern genetics and medicine, including how a protein called HSP90 acts as a capacitor modulate evolution, a process that can even be addressed pharmacologically and possibly used as a strategy in some forms of cancer. Her work also contributes to both our understanding of several protein folding diseases such as Parkinson's and Huntington's and seeks to tackle them head on.

Lastly, we discussed her discovery on how to transform yeast prions (similar to the misfolded proteins linked to mad cow disease) into nanowires as used in nanotechnology.

Hosts: Marc Pelletier and Leo Laporte

Guest: Dr. Susan Lindquist

For more information, links, and discussions visit the Futures in Biotech blog.

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