Extend Podcast with Darshan Shah, MD

Latest Episodes:

68. Jen Batchelor: The Real Reason You're Burned Out (And It's Not Your Job) Jun 05, 2025

Show notes

Most people are treating stress with the wrong tools, and it's silently sabotaging their longevity.

In this episode of Extend, I sit down with Jen Batchelor, Ayurvedic health optimizer and co-founder of Kin Euphorics, to talk about what your nervous system actually needs to feel calm, connected, and well. We dive into what adaptogens are really doing in your body, why saffron might be one of the most powerful neuroprotective tools available, and how homeostasis—not hustle—is the key to better energy and long-term health.

We also explore the hidden costs of loneliness, the biology behind joy, and why redefining pleasure might be the most underrated health hack of all.

Jen Batchelor is the co-founder of Kin Euphorics, a non-alcoholic beverage company blending adaptogens, nootropics, and ritual to support mood, connection, and recovery

We Also Discuss:

Adaptogens aren't supplements—they're system whisperers
Saffron for your brain? Yep, it's a thing
The 30-second nervous system reset you're not doing
She went from desert moonshine to alcohol-free empire
Longevity hack? Real connection > green juice

Use code EXTEND20 to get 20% off at kineuphorics.com.

Thank You to Our Sponsors:

Timeline: Upgrade your energy from within! MitoPure by Timeline helps power up your cells, supporting muscle strength, mental clarity, and overall vitality. Stay active, sharp, and strong at any age!
Deliverance: Give your liver the care it deserves! Deliverance is a powerful plant-based formula designed to support and restore liver health. Get 10% off your first order with code DRSHAH at loveyourliver.com

Learn more about Dr. Shah:

Website: https://www.drshah.com/

Clinic: https://www.next-health.com/

Instagram: https://www.instagram.com/darshanshahmd/

Learn more about Jen Batchelor: Website:https://www.kineuphorics.com/

Instagram: https://www.instagram.com/kineuphorics/

Instagram: https://www.instagram.com/jenofkin

67. Chris Mirabile: How to Reverse Your Biological Age (and Why Your Doctor Isn't Talking About It) Jun 03, 2025

Show notes

What if your real age isn't on your driver's license—but buried in your biology?

In this episode of Extend, I'm joined by Chris Mirabile, founder of NOVOS and one of the few people actually slowing down his pace of aging. We break down why the average person is aging faster than they realize, and how mainstream medicine is decades behind when it comes to prevention.

We get into the 12 hallmarks of aging, why free radicals aren't your enemy, how biological clocks really work, and the lifestyle and supplement strategies that are scientifically shown to make you younger from the inside out.

Chris Mirabile is the founder and CEO of NOVOS, a longevity biotech company backed by leading researchers and data. After surviving a brain tumor at age 16, he became obsessed with the science of living better, longer.

Let's dive in.

We Also Discuss:

Why Healthspan Matters More Than Lifespan
12 Cellular Reasons You're Aging Faster Than You Should
Mitochondria, Free Radicals, and the Truth About Energy Decline
Can We Reprogram Aging? The Science Behind Epigenetics
The Real Pathways to Longevity (That Most Doctors Ignore)
How Your Daily Habits Are Speeding Up—or Slowing Down—Aging
What Your Biological Age Says About Your Future Health
From Supplements to Stem Cells: What Actually Works to Slow Aging

Thank You to Our Sponsors:

TruNiagen: Whether you are looking to stay sharp, feel more energized or simple age better, go to https://www.truniagen.com/
IFit: If you are looking to elevate your home gym fitness experience with the best in fitness tech, choose IFIT. Go to https://www.ifit.com/
NextHealth: Your destination for cutting-edge health optimization—from IV therapy to hormone balancing. Explore at https://www.next-health.com/
Vitaboom: For supplements you can trust and wellness solutions tailored to your health, visit https://vitaboom.com/

Website: https://www.drshah.com/

Clinic: https://www.next-health.com/

Instagram: https://www.instagram.com/darshanshahmd/

Learn more about Chris Mirabile

Website: https://slowmyage.com/ Instagram: https://www.instagram.com/slowmyage

66. Steve Martocci: Inside the $50B Supplement Scam, But With a Fix May 29, 2025

Show notes

Most supplements don't work. Some might actually harm you. That's the hard truth no one in the $50 billion supplement industry wants to say out loud—but we will.

In today's episode of Extend, I'm joined by Steve Martocci, co-founder of SuppCo, to expose what's really going on behind the labels. We break down why "clinically dosed" means nothing, why the FDA isn't protecting you, and how two identical bottles can deliver completely different outcomes.

We also dive into the myth of "FDA-approved" supplements, the loopholes brands exploit to mislead consumers, and why Europe bans ingredients still allowed in U.S. formulas.

If you take supplements—or recommend them—this episode is essential listening. It's time to stop guessing, stop wasting money, and start demanding real data, transparency, and strategy.

Steve Martocci is the co-founder of SuppCo, a platform bringing science-backed clarity to the chaos of the supplement industry.

We Also Discuss:

The dirty truth behind supplement "trust scores"
How shady supplements keep making it to your shelf
Supplement demand is exploding… but quality isn't
Why "clinically dosed" doesn't mean clinically effective
How professional brands still get away with underdelivering
Why you're probably taking the wrong supplements for your goals
How SuppCo is flipping the industry on its head
The tool that finally helps you trust what you're taking

Thank You For Our Sponsors:

Deliverance: Give your liver the care it deserves! Deliverance is a powerful plant-based formula designed to support and restore liver health. Get 10% off your first order with code DRSHAH at loveyourliver.com

Timeline: Upgrade your energy from within! MitoPure by Timeline helps power up your cells, supporting muscle strength, mental clarity, and overall vitality. Stay active, sharp, and strong at any age! Claim 10% off your first order now at timeline.com/DrShah

Learn more about Dr. Shah:

Website: https://www.drshah.com/

Clinic: https://www.next-health.com/

Instagram: https://www.instagram.com/darshanshahmd/

Learn more about Steve Martocci:

Instagram: https://www.instagram.com/smart/

Instagram: https://www.instagram.com/joinsuppco/

Website: https://supp.co/

➡️ Listeners can use the code "EXTEND15" to receive 15% off their personalized supplement protocol on https://supp.co/

65. Dr. Austin Perlmutter: Why You're Addicted to Bad Habits (And How to Reverse It) May 27, 2025

Show notes

What if the reason you can't focus, feel chronically overwhelmed, or keep slipping into the same unhealthy habits… isn't a discipline problem, it's your brain's biology working against you?

In this episode of Extend, I'm joined by Dr. Austin Perlmutter, board-certified internal medicine physician and neuroscientist, to explore how inflammation hijacks your brain's decision-making and what you can do to take back control.

We dig into why modern life wires your brain for reactivity over intention, the shocking impact of neuroinflammation on mood and behavior, and how daily habits are either fueling the fire or calming the system. You'll learn practical tools to reduce brain-body inflammation, support cognitive clarity, and make better choices even under stress.

Dr. Austin Perlmutter, MD is a board-certified internal medicine physician, neuroscientist, and New York Times bestselling author.

Let's dive in!

We Also Discuss:

Why Brain Health Isn't Just in Your Head
The Overlooked Link Between Metabolism and Mental Clarity
What Chronic Inflammation Is Really Doing to Your Brain
How Long-Term Stress Rewires Your Biology
Rethinking Depression: It's Not Just in the Mind
Can You Rewire Your Brain? The Science of Neuroplasticity
Are Psychedelics the Future of Mental Health?
The Brain-Sleep Connection You Can't Afford to Ignore

Thank You to Our Sponsors:

TruNiagen: Whether you are looking to stay sharp, feel more energized or simple age better, go to https://www.truniagen.com/IFit: If you are looking to elevate your home gym fitness experience with the best in fitness tech, choose IFIT. Go to https://www.ifit.com/NextHealth: Your destination for cutting-edge health optimization—from IV therapy to hormone balancing. Explore at https://www.next-health.com/Vitaboom: For supplements you can trust and wellness solutions tailored to your health, visit https://vitaboom.com/

Learn more about Dr. Shah:

Website: https://www.drshah.com/

Clinic: https://www.next-health.com/

Instagram: https://www.instagram.com/darshanshahmd/

Learn more about Dr. Austin Perlmutter:

Website: https://www.austinperlmutter.com/ Instagram: https://www.instagram.com/draustinperlmutter/

Lichen air: Get 10% off at https://lichen-air.myshopify.com/?rfsn=8715882.7adc91 using code DRSHAH10

Sources: Effects of different physical activities on brain-derived neurotrophic factor

Dr. Austin's research on Tartary Buckwheat: www.bigboldhealth.com

64. LP(a): The Massively Important, But Totally Overlooked Biomarker of Heart Attacks, Strokes, and Heart Disease May 22, 2025

Show notes

In this episode of Extend, we're digging into one of the most dangerous—and most overlooked—drivers of heart disease: LP(a).

You could have a clean lifestyle, normal labs, and still be at high risk for a heart attack or stroke. Why? Because LP(a) isn't included in standard cholesterol tests—and 1 in 5 people have elevated levels without knowing it.

I break down what LP(a) actually is, why it's more inflammatory and damaging than LDL, and how it contributes to plaque, heart attacks, strokes, and valve disease. You'll learn why lifestyle changes don't lower it, what to do if your levels are high, and how cutting-edge RNA therapies could offer hope.

I also share exactly which labs and scans to request so you're not flying blind.

➡️ If you care about preventing cardiovascular disease, this is essential listening. It's time to add LP(a) to the conversation.

I Also Discuss:

The stealth cholesterol marker no one's testing for
Think your cholesterol panel is fine? Here's what it's missing
LP(a): the hidden culprit behind "healthy" heart attacks
This could be why young people are having strokes
The one stat that should have everyone talking
Got high LP(a)? Here's your action plan
The game-changing drugs that silence LP(a) at the source

Thank You for Our Sponsors:

Deliverance: Give your liver the care it deserves! Deliverance is a powerful plant-based formula designed to support and restore liver health. Get 10% off your first order with code DRSHAH at loveyourliver.com
Timeline: Upgrade your energy from within! MitoPure by Timeline helps power up your cells, supporting muscle strength, mental clarity, and overall vitality. Stay active, sharp, and strong at any age! Claim 10% off your first order now at timeline.com/DrShah

Learn more about Dr. Shah:

Website: https://www.drshah.com/

Clinic: https://www.next-health.com/

Instagram: https://www.instagram.com/darshanshahmd/

63. Charles Brenner: NAD, Energy, and Longevity: The Secret Nobody Told You About May 20, 2025

Show notes

What if the reason you're tired, inflamed, or not recovering the way you used to has nothing to do with aging, and everything to do with your NAD system being under attack?

In this episode of Extend, I'm joined by Dr. Charles Brenner, the scientist who discovered nicotinamide riboside (NR) and one of the leading experts on NAD metabolism. We unpack why NAD is so critical for energy, repair, and resilience, and why simply "taking NAD" isn't the solution most people think it is.

We also break down the key lifestyle factors quietly draining your NAD levels, the real difference between NMN, NR, niacin, and IV NAD, and why NR may be the safest and most effective way to support your body's natural repair systems. Dr. Brenner also shares the science behind NAD's role in inflammation, immunity, and recovery, and why placebo-controlled research is the missing piece in so many longevity conversations.

Dr. Charles Brenner is the Alfred E. Mann Family Foundation Chair in Diabetes and Cancer Metabolism at City of Hope and a leading authority on NAD metabolism. His work bridges fundamental science with real-world application.

We Also Discuss:

Why NAD Is the Missing Link in Energy, Repair, and Longevity
The Truth About NAD Decline—and What's Really Draining Your Levels
NR vs. NMN: The NAD Debate That Actually Matters
Is Oral NR Better Than IV NAD? Here's What the Research Says
How NAD Impacts Inflammation, Immunity, and Recovery
The Gaps in NAD Science and Why They Matter

Thank You to Our Sponsors:

Learn more about Dr. Shah:

Website: https://www.drshah.com/

Clinic: https://www.next-health.com/

Instagram: https://www.instagram.com/darshanshahmd/

Learn more about Dr. Charles Brenner:

Website: brennerlab.netInstagram: @charlesmbrenner

62. David Nurse: How to Rewire Your Brain for Success (Without Hustling Harder) May 15, 2025

Show notes

Most people know mindset matters, but almost no one knows how to actually train it for better health, performance, and longevity.

In today's episode of Extend, I'm joined by David Nurse, NBA mindset coach and best-selling author. We dive deep into why mindset is the real missing piece in most health optimization plans, and how flow states, identity shifts, and daily systems can radically change your outcomes.

We also break down why your mindset is the ignition switch for success, how to tap into flow states more consistently (and why it matters), the truth about goals vs. systems, and why goals alone fail, how identity shapes your health, your results, and your future, and actionable tools you can start using today to rewire your brain for growth.

David Nurse is a top NBA mindset coach, best-selling author, and motivational speaker specializing in high-performance habits. David is the author of Pivot & Go, Breakthrough, Do It, and the upcoming book The Flow Code.

Tune in!

We Also Discuss:

• How the Health Optimization Summit Changes Your Mindset Game • Why Flow States Are the Missing Link to Peak Performance • Focus vs. Flow: Why Most People Get It Wrong • Simple Tools to Build Unshakable Confidence and Reset Fast • The 4-Step Formula to Trigger Flow on Command • Why Chasing Goals Alone Kills Your Momentum • The Morning Routine that Rewires Your Brain for Success • Encouragement, Habits, and the Real Secret to Sustainable Growth

Thank You for Our Sponsors:

Deliverance: Give your liver the care it deserves! Deliverance is a powerful plant-based formula designed to support and restore liver health. Get 10% off your first order with code DRSHAH at loveyourliver.com
Timeline: Upgrade your energy from within! MitoPure by Timeline helps power up your cells, supporting muscle strength, mental clarity, and overall vitality. Stay active, sharp, and strong at any age! Claim 10% off your first order now at timeline.com/DrShah

Learn more about Dr. Shah:

Website: https://www.drshah.com/

Clinic: https://www.next-health.com/

Instagram:@darshanshahmd

Learn more about David Nurse Instagram: @davidnursenbaTwitter: @DavidNurseNBA

YouTube: David Nurse

61. Dr. Aly Cohen: The #1 Detox Mistake You're Probably Making (and What Actually Works) May 13, 2025

Show notes

What if the hidden toxins in your everyday life are secretly sabotaging your health, hormones, and longevity? Most people underestimate how deeply their health is impacted by toxins—and conventional medicine isn't addressing the root of the issue.

In this episode of Extend, I'm joined by Dr. Aly Cohen, renowned integrative rheumatologist, environmental health expert, and author of the upcoming book, Detoxify. We uncover the shocking truth about the tens of thousands of unregulated chemicals lurking in your home, food, water, and even your skincare products—and reveal why detox isn't about trendy cleanses, but smarter daily choices.

We dive into why microplastics have infiltrated every part of your body (including your brain), how seemingly innocent products are disrupting your hormones, metabolism, and immune system, and what practical steps you can immediately take to dramatically reduce your toxic exposure.

Dr. Cohen shares eye-opening facts on why your tap water is more polluted than you think, why household dust is toxic waste in disguise, and how simple nutritional strategies can powerfully protect you from environmental harm.

We Also Discuss:

Detox Myths That Even Most Doctors Believe
The Shocking Truth About How Toxins Sabotage Your Immune System
Easy Daily Habits to Dramatically Reduce Your Toxic Load
Why Reverse Osmosis Is a Non-Negotiable for Your Health
Practical Tips to Navigate a Toxin-Free Lifestyle (Without Stress)
Hidden Sources of Microplastics You Use Every Single Day
Detox Done Right: Supporting Your Liver & Kidneys Naturally
The "Four A's" Method to Protect Your Health from Hidden Chemicals

Thank You to Our Sponsors:

TruNiagen: Whether you are looking to stay sharp, feel more energized or simple age better, go to https://www.truniagen.com/
IFit: If you are looking to elevate your home gym fitness experience with the best in fitness tech, choose IFIT. Go to https://www.ifit.com/
NextHealth: Your destination for cutting-edge health optimization—from IV therapy to hormone balancing. Explore at https://www.next-health.com/
Vitaboom: For supplements you can trust and wellness solutions tailored to your health, visit https://vitaboom.com/

Learn more about Dr. Shah:

Website: https://www.drshah.com/
Clinic: https://www.next-health.com/
Instagram: https://www.instagram.com/darshanshahmd/

Learn more about Dr. Aly Cohen:

Website: www.alycohenmd.com
Instagram: @TheSmartHuman

60. Cholesterol Myths You Still Believe (And What to Track Instead) May 08, 2025

Show notes

In this episode of Extend, we're rethinking everything you've been told about cholesterol. For decades, the focus has been on lowering LDL, but that's only part of the story. The truth? LDL and total cholesterol are outdated metrics. If you're still relying on those alone to assess your heart health, you're missing the bigger picture.

I'll break down why ApoB is the single most important number to track when it comes to cardiovascular disease, and how it gives a much clearer view of your real risk. You'll learn how plaque forms, why inflammation and metabolic dysfunction matter just as much as cholesterol, and how to approach your heart health with precision.

I'll also cover how to lower ApoB naturally, when medication might make sense, and how advanced scans like CLEARLY can help guide your strategy. ➡️If longevity is your goal, this episode is a must-listen. Let's move beyond outdated labs and into next-gen heart prevention.

I Also Discuss:

Why LDL Is Outdated (And What to Track Instead)
The Real Cause of Plaque in Your Arteries
ApoB: The #1 Biomarker for Heart Health
How to Lower Cholesterol Without Statins
The Longevity Approach to Cardiovascular Disease

Thank you for our Sponsors:

Deliverance: Give your liver the care it deserves! Deliverance is a powerful plant-based formula designed to support and restore liver health. Get 10% off your first order with code DRSHAH at loveyourliver.com
Timeline: Upgrade your energy from within! MitoPure by Timeline helps power up your cells, supporting muscle strength, mental clarity, and overall vitality. Stay active, sharp, and strong at any age! Claim 10% off your first order now at timeline.com/DrShah

Learn more about Dr. Shah: Website: https://www.drshah.com/

Clinic: https://www.next-health.com/

Instagram: https://www.instagram.com/darshanshahmd/

59. Joel Greene: The Nutrition Secret That Reverses Fatigue and Brain Fog May 06, 2025

Show notes

What if the secret to better energy, fat loss, and gut health wasn't more discipline… but a smarter strategy? Most people are hacking the wrong system—and it's backfiring. In this episode of Extend, I'm joined by Joel Greene, creator of the VEEP Nutrition System and one of the most innovative minds in metabolic health. We break down the science behind fat loss, blood sugar regulation, gut health, and why conventional diet advice is failing most people.

We dive into how your microbiome controls more than just digestion, why fasting isn't one-size-fits-all, and what your body really needs to burn fat and build lasting energy. Joel also shares cutting-edge insights on short-chain fatty acids, protein misconceptions, and how your environment is silently shaping your metabolic function.

If you want to understand how your body actually works—and how to fuel it for longevity and performance—this conversation is a game-changer.

We Also Discuss:

How the Wellness Industry Got It All Wrong
The Hidden Link Between Poor Sleep and Your Diet
From Sick to Superhuman: Joel's Radical Health Turnaround
The Forgotten Foods That Heal Your Gut
Why Most Gut Protocols Fail (And What to Do Instead)
Think You're Eating Healthy? Think Again.
The Missing Piece in Every Metabolic Plan
It's Not Just What You Eat—It's When and How

Thank You to Our Sponsors:

TruNiagen: Whether you are looking to stay sharp, feel more energized or simple age better, go to https://www.truniagen.com/
IFit: If you are looking to elevate your home gym fitness experience with the best in fitness tech, choose IFIT. Go to https://www.ifit.com/
NextHealth: Your destination for cutting-edge health optimization—from IV therapy to hormone balancing. Explore at https://www.next-health.com/
Vitaboom: For supplements you can trust and wellness solutions tailored to your health, visit https://vitaboom.com/

Learn more about Dr. Shah:

Website: https://www.drshah.com/

Clinic: https://www.next-health.com/

Instagram: https://www.instagram.com/darshanshahmd/

Learn more about Joel Greene:

Website: https://www.veepnutrition.com/

Instagram: https://www.instagram.com/realjoelgreene/?hl=en