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    Health & Fitness

    Docs Who Lift

    Drs. Spencer and Karl Nadolsky talk about nutrition, medicine, and fitness through the lens of two physicians who lift weights. Both doctors are former NCAA division 1 wrestlers who have gone into medicine. Dr. Spencer Nadolsky is a board certified family physician specialized in obesity medicine and lipidology. Dr. Karl Nadolsky is a board certified endocrinologist also specialized in obesity medicine.

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    Copyright: © Docs Who Lift

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    Latest Episodes:
    Do You Really Lose Muscle on Semaglutide or Tirzepatide? Aug 22, 2025
    Show notes

    Takeaways

    • The podcast features Dr. Grant Tinsley, a body composition expert.
    • The discussion revolves around a case series on body composition effects.
    • GLP-1 receptor agonists are a focus of the research.
    • The importance of resistance training in weight loss is emphasized.
    • Patient case studies provide insights into individual experiences.
    • The first patient lost a significant amount of fat mass while preserving lean mass.
    • The second patient achieved remarkable body composition changes in a short time.
    • The third patient showed positive changes over a longer duration.
    • The need for more randomized trials is highlighted.
    • The conversation underscores the role of exercise and nutrition in weight management.
      Tap or Click here to see more from Dr. Grant
      Tap here for scientific references in this episode.

    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.


    Predatory Lab Testing: What They’re Not Telling You Aug 16, 2025
    Show notes

    Takeaways

    Direct-to-consumer lab testing is on the rise, with significant marketing efforts behind it.

    Many patients feel brushed off by traditional healthcare providers, leading them to seek alternative testing options.

    Communication between patients and healthcare providers is often inadequate, contributing to misunderstandings about health.

    Over-testing can lead to unnecessary anxiety and misinterpretation of results.

    Fitness influencers often promote lab testing without proper medical training, which can be harmful.

    There is a need for ethical practices in lab testing and patient care.

    Patients should be cautious of companies that upsell supplements based on lab results.

    The healthcare system often fails to provide adequate time for patient concerns to be addressed.

    Understanding lab results requires skilled interpretation, which is often lacking in direct-to-consumer models.

    A collaborative approach among healthcare professionals is necessary to improve patient outcomes.
    Click to join Dr. Spencer's online clinic if you need help with this

    Click here to check out Barbell Medicine


    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.


    CVS Pulled the Plug on Zepbound?! Aug 08, 2025
    Show notes

    In this episode of the Dr. Lift podcast, hosts Dr. Spencer Nadolsky and Dr. Karl discuss the recent changes in obesity medication coverage, particularly focusing on the CVS Caremark decision to drop ZEPBound from their formulary in favor of Wegovi. They explore the implications of this decision for patients and providers, the role of pharmacy benefit managers (PBMs) in healthcare, and the ongoing advocacy efforts to ensure access to effective obesity treatments. The conversation highlights the complexities of insurance coverage, the need for patient-centered care, and the importance of making medications more affordable.
    - The recent changes in obesity medication coverage have raised concerns among providers and patients.

    - CVS Caremark's decision to drop ZEPBound has sparked a petition advocating for better access to medications.

    - Pharmacy Benefit Managers (PBMs) play a significant role in determining medication coverage and costs.

    - There is a need for more nuanced insurance policies that consider patient needs and clinical severity.

    - Advocacy efforts are crucial in reversing negative trends in medication coverage.

    - Patients often face challenges with prior authorization processes when switching medications.

    - The cost of obesity medications is a significant barrier to access for many patients.

    - Insurance companies are increasingly dropping coverage for anti-obesity medications, impacting patient care.

    - The conversation emphasizes the importance of patient-centered care in obesity treatment.

    - There is a call for making obesity medications more affordable and accessible to patients.

    https://www.change.org/p/stop-cvs-caremark-s-zepbound-ban-restore-coverage-of-the-superior-obesity-medication

    Click to join Dr. Spencer's online clinic if you need help with this


    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.


    More Than Weight Loss? GLP-1s and Cardiovascular Risk Aug 03, 2025
    Show notes

    In this episode of the Dr. Lift podcast, hosts Dr. Spencer Nadolsky and Dr. Karl discuss the Surpass CVOT trial, which evaluates the cardiovascular outcomes of Monjaro compared to Dulaglutide (Trulicity). They delve into the significance of the trial, the implications of the results, and the potential benefits of Monjaro for patients with type 2 diabetes and cardiovascular risks. The conversation highlights the importance of understanding cardiovascular outcome trials and the evolving landscape of diabetes medications.


    Takeaways:

    The Surpass CVOT trial compares Mounjaro to Dulaglutide.

    Dulaglutide has shown cardiovascular benefits in previous trials.

    The trial results indicate Monjaro is at least not inferior to Dulaglutide.

    There is a trend towards better cardiovascular outcomes with Mounjaro.

    Weight loss and glycemic control are significant benefits of Mounjaro.

    The trial did not include a placebo, but used a putative analysis.

    The results are reassuring for patients at high cardiovascular risk.

    The conversation emphasizes the importance of comprehensive treatment for metabolic diseases.

    The hosts express enthusiasm for the potential of Mounjaro.

    Future discussions will delve deeper into the trial's findings.


    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.


    Semaglutide vs. Tirzepatide: Are We Closing the Gap? Jul 24, 2025
    Show notes

    How the STEP-UP trial came to life, and what made the 7.2mg dose possible

    What the data actually says about weight loss and side effects at higher doses

    Why trial design, pharmacokinetics, and estimands matter more than you think

    What’s coming next in obesity meds: duals, triples, and even antagonists

    The real talk on intermittent fasting, access issues, and preaching vs. science

    Sign up for Dr. Spencer''s Clinic


    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.


    Clinical vs Anthropometric Obesity Jul 02, 2025
    Show notes

    Takeaways

    • The study examines the overlap between clinical and anthropometric obesity.
    • Anthropometric measures include waist circumference, waist-to-hip ratio, and BMI.
    • Challenges exist in applying the Lancet Commission's definitions in clinical practice.
    • Metabolically healthy obesity is a debated topic in obesity research.
    • The study highlights the importance of data from the All of Us Research Program.
    • There is a significant prevalence of preclinical obesity in individuals with normal BMI.
    • The classification of obesity may need to shift focus towards overweight individuals.
    • The study's findings suggest a need for more nuanced definitions of obesity-related diseases.
    • Future research will explore the transition from preclinical to clinical obesity.
    • The conversation emphasizes the importance of real-world data in understanding obesity.

    Click here to see the study

    Follow Dr. Yao on X here

    Follow Dr. Blaha on X here

    Click here to join Dr. Spencer's online clinic


    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.


    GLP-1 meds and macular degeneration Jun 23, 2025
    Show notes

    Learn what age-related macular degeneration (AMD) is

    What causes AMD

    The types of AMD

    The update on NAION - listen to last year's podcast all about it

    Why we aren't too concerned

    Click here to join Dr. Spencer's online clinic Vineyard

    Click to read the JAMA AMD article

    Click to read the Ophthalmology journal AMD article


    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.


    Menopause, MHT, and GLP-1 medicines Jun 12, 2025
    Show notes
    • Menopausal hormonal therapy should not be a blanket recommendation for everyone going through menopause
    • Weight management in women is influenced by hormonal changes throughout life stages.
    • Retrospective analyses can provide insights but have limitations.
    • The wellness industry often oversimplifies complex medical issues.
    • Hormonal replacement therapy may have subtle benefits for weight management.
    • Confounding factors like SSRIs can complicate weight loss efforts.
    • A holistic approach is essential for managing women's health during menopause.
    • Education and awareness are crucial for women navigating menopause.
    • Future research should focus on randomized controlled trials for better clarity.
    • Understanding individual patient experiences is key to effective treatment.

    Click here to see her study

    Click here to follow Dr. Tchang on X

    Click here to join Dr. Spencer's clinic Vineyard


    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.


    The Science of Myostatin inhibitors, GLP-1 meds and Muscle Mass Jun 06, 2025
    Show notes
    • Dr. Grant Tinsley joins the discussion as the body composition expert.
    • Myostatin is a key regulator of muscle growth.
    • Wendy Whippete the most jacked muscled up dog
    • The concern of GLP-1 receptor agonists and muscle mass loss.
    • Overview of Courage trial looking at semaglutide and trevogrumab and lean mass loss
    • Upcoming Believe trial coming out (bimagrumab and semaglutide)
    • Exercise remains crucial for muscle health and function.
    • MRI data from SURPASS MRI provides new insights into muscle volume changes.
    • The combination of medications may have varying effects on muscle mass.
    • Caution is advised regarding the long-term effects of new drugs.
    • Clinical benefits of medications often outweigh concerns about muscle loss.
    • Future research will explore the synergy between exercise and medication.

    Other docs who lift podcasts with Dr. Grant:

    Tirzepatide muscle loss

    Lean mass loss and GLP-1 meds


    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.


    Current State of Nutrition Research and MAHA May 29, 2025
    Show notes

    Takeaways:

    • The MAHA report aims to address public health issues but lacks actionable policies.
    • Historical context is crucial for understanding current dietary guidelines.
    • Funding for nutrition research has been inadequate, impacting the quality of data.
    • Public perception of nutrition often outpaces scientific evidence.
    • The evolution of dietary guidelines reflects political and social influences.
    • There is a need for more rigorous nutrition science to inform policy.
    • The dietary guidelines have not significantly improved population health metrics.
    • Political will is essential for implementing effective nutrition policies.
    • Nutrition science faces challenges in funding and research infrastructure.
    • The MAHA report's recommendations may be more performative than substantive. Food policy changes are often superficial and ineffective.
    • There is a significant disconnect between policy and actual health outcomes.
    • Nutrition science is underfunded and lacks high-quality research.
    • Misinformation in nutrition can lead to harmful public health outcomes.
    • The focus on food additives distracts from more pressing issues like obesity.
    • Experts are being sidelined in favor of political agendas.
    • Public trust in health recommendations has eroded post-COVID.
    • Nutrition policies need to be based on solid scientific evidence.
    • The food industry needs clearer guidance on reformulating products.
    • Future nutrition policies must prioritize public health over political gain

    Read Dr. Kevin's paper

    Follow Dr. Kevin on instagram

    Join Dr. Spencer's clinic


    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.


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