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Virtual Therapy Jan 05, 2015

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E-Therapy has come a long way since the (slightly tongue in cheek) days of Eliza, a very early attempt at computer based psychotherapy. Eliza was little more than an algorithm that spotted patterns in words and returned empty, yet meaningful-sounding questions back at the user.

All sorts of e-therapies are now available to help low-moderate level mental health issues.

But could Virtual Reality technology bring the next great leap in our understanding of mental processes, and, in turn, be the basis of future psychotherapies? Quentin Cooper meets some of the researchers trying to find out.

Image: Quentin Cooper in a body-tracking virtual reality suit, Copyright: Mel Slater

Animal Personality Dec 29, 2014

Show notes

Professor Adam Hart explores the newest area in the science of animal behaviour – the study of personality within species as diverse as chimpanzees, song birds, sharks and sea anenomes. What can this fresh field of zoology tells us about the variety of personality among humans?

We are all familiar with the variety of temperament and character in the dog, Canis lupus familiaris, but this is the product of selective breeding by humans over generations. A more surprising revelation is that up and down the animal kingdom, Nature favours a mix of personality types within a species. Oxford ornithologists working in Wytham Woods have discovered that in a small bird species such as the great tit, both bold and shy individuals prosper in different ways.

The same applies to hermit crabs and sea anemones in the rock pools along the South Devon coast. In these creatures, Dr Mark Briffa sees a stripped-down equivalent of the extraversion-intraversion dimension of human personality.

In sharks, researchers have discovered that there are sociable individuals and others who prefer their own company.

At the University of Exeter, an experiment with a smaller fish species, the guppy, suggests that a mix of personality types in a population favours the prospects of both the group and individual members of that group. A similar finding in great tits has come out of the woods at Wytham.

Adam Hart asks how relevant the recent discoveries in animal personality research are to understanding the nature and evolution of personality in people.

Producer: Andrew Luck-Baker

Picture: A great tit in a nest, Credit: Nicole Milligan

Can Maths Combat Terrorism? Dec 22, 2014

Show notes

Dr Hannah Fry investigates the hidden patterns behind terrorism and asks whether mathematics could be used to predict the next 9/11. When computer scientists decided to study the severity and frequency of 30,000 terrorist attacks worldwide, they found an distinctive pattern hiding in the data. Even though the events spanned 5,000 cities in 187 countries over 40 years, every single attack fitted neatly onto a curve, described by an equation known as a 'power law'.

Now this pattern is helping mathematicians and social scientists understand the mechanisms underlying global terrorism. Could these modelling techniques be used to predict if, and when, another attack the size of 9/11 will occur?

New Space to Fly Dec 15, 2014

Show notes

As our skies become more crowded Jack Stewart examines the long awaited modernisation of air traffic control. With traffic predicted to reach 17 million by 2030 more flights will mean more delays. For many a new approach to controlling flights is long overdue since aircraft still follow old and often indirect routes around the globe, communication between the ground and air is still by VHF radio, and any flexibility is heavily constrained by a fragmented airspace operated by many national authorities.

Jack Stewart examines how aviation technologists have come up with a radical solution. It enables pilots, once airborne, to choose their own route. 'Free Routing', it is argued, will allow more direct flights, no planes to be caught up in holding patterns, reduced fuel emissions and flights departing and arriving on time. Crucially, free routing will enable a tripling of flights than currently we are capable of controlling. But will the ability of pilots to choose their own routes increase the risk of collision? Researchers argue it will in fact produce even safer skies. Jack Stewart visits NATS air traffic control centre that annually looks after the safety of over two million British airspace to hear how such a system could evolve.

Jack finds out how free routing could work from the engineers at Indra UK – who are trialling such a system in airspace controlled by the NATS Prestwick air traffic control centre. In a new approach they are turning 'reactive' air traffic control into a more strategic approach with computer designed flight trajectories utilising much of the currently underused satellite navigation that is fitted on modern aircraft. It will enable aircraft to be safely spaced closer together and at the same time predict potential 'conflicts' of spacing much further ahead of the routes being taken, leaving less room for human error.

And as automation begins to play a greater role in all aspects of flight planning and control is the era of pilotless planes moving a step closer?

(Photo: NATS air traffic control centre. Credit: NATS)

Vagus Nerve Dec 08, 2014

Show notes

Many people are living with chronic diseases such as rheumatoid arthritis and inflammatory bowel conditions in which the body attacks itself. Although drug treatments have improved over recent years they do not work for everyone and can have serious side effects.

Now researchers such as neurologist Dr Kevin Tracey of the Feinstein Institute for Medical Research, and rheumatologist professor Paul-Peter Tak of Amsterdam University, are trying a new approach to improving the lives of these patients. They are firing electrical pulses along the vagus nerve, a major nerve that connects the brain with all the organs. The technology to do this has been around for some decades as stimulating the vagus nerve has been used to help people who have epilepsy that is not controlled with drugs since the 1990s. Gaia Vince talks to these pioineers of this new field of research. And, she hears how there may be ways of improving the tone of the vagal nerve using meditation.

(Image: Vagus Nerve Stimulation. Credit: Getty Images)

Elspeth Garman Dec 01, 2014

Show notes

Jim al-Khalili talks to professor Elspeth Garman about a technique that has led to 28 Nobel Prizes in the last century.

X- ray crystallography, now celebrating its 100th anniversary, is used to study the internal structure of matter. It may sound rather arcane but it is the reason we now know the structure of hugely important molecules, like penicillin, insulin and DNA. But while other scientists scoop up prizes for cracking chemical structures, Elspeth works away behind the scenes, (more cameraman than Hollywood star), improving the methods and techniques used by everybody working in the field.

If only it was as simple as putting a crystal in the machine and printing off the results. Growing a single crystal of an enzyme that gives TB its longevity took Elspeth's team no less than 15 years. No pressure there then when harvesting that precious commodity.

(Photo: Professor Elspeth Garman)

Painful Medicine Nov 24, 2014

Show notes

Addictions researcher, Dr Sally Marlow, investigates fears that easy access to powerful painkillers could be creating a large, but hidden problem of addiction. Painkillers are widely available over the counter, and combinations containing codeine, which is addictive, can be purchased from pharmacists and on the internet.

Teenager, Alice, tells Sally about secretly buying huge numbers of painkillers on her way to school while she was wearing her school uniform. She used her lunch money to buy multiple packs from several stores, switching shops when she was questioned by pharmacists. And Steve describes how his serious codeine addiction began after treating tooth pain with the drug. The side effects helped his anxiety and for years he was doctoring tablets in order to increase his codeine intake.

Some health professionals believe easy access is fuelling a potential health crisis and say those with serious dependency problems, are hidden below the healthcare radar. Only a tiny percentage of people with an addiction to painkillers find their way to traditional substance misuse services, fuelling concerns that there is a large, but hidden group, who are not getting help with their dependency.

David Grieve, who set up the charity Over-Count, 21 years ago, after his own serious addiction to over-the-counter cough mixture, believes the number of people dependent on painkillers is growing, fuelled by easy availability on the internet. Between 30-35% of visitors to his website say when they are refused purchases by pharmacists, they buy online instead.

Fabrizio Schifano, professor of Clinical Pharmacology at the University of Hertfordshire and a member of the government's Advisory Council on the Misuse of Drugs, demonstrates how easy it is to buy potent painkillers online and Dr Paolo DeLuca, a senior research fellow in addictive behaviour at King's College, London, tells Sally about a three year international study - the Codemisused Project - which aims to discover the scale of codeine use and misuse. Dr DeLuca is leading the British arm of the study and he hopes that research will fill the current gap in knowledge so that if action is needed to reduce the risk to individuals, it can be based on evidence.

(Photo: Medicinal pills and tablets)

Chris Toumazou Nov 17, 2014

Show notes

European Inventor of the Year, Chris Toumazou, reveals how his personal life and early research lie at the heart of his inventions.

As chief scientist at the Institute of Biomedical Engineering at Imperial College London, Chris inspires engineers, doctors and other scientists to create medical devices for the 21st Century.

Applying silicon chip technology, more commonly found inside mobile phones, he tackles seemingly insurmountable problems in medicine to create devices that bridge the electronic and biological worlds - from a digital plaster that monitors a patient's vital signs to an artificial pancreas to treat diabetes.

His latest creation, coined a 'lab on a chip', analyses a person's DNA within minutes outside the laboratory. The hand-held device can identify genetic differences which dictate a person's susceptibility to hereditary diseases and how they will react to a drug like warfarin, used to treat blood clots.

(Photo: Chris Toumazou, BBC copyright)

The Making of the Moon Nov 10, 2014

Show notes

It is the nearest and most dominant object in our night sky, and has inspired artists, astronauts and astronomers. But fundamental questions remain about our only natural satellite. Where does the Moon come from?

Although humans first walked on the Moon over four decades ago, we still know surprisingly little about the lunar body's origin. Samples returned by the Apollo missions have somewhat confounded scientists' ideas about how the Moon was formed. Its presence is thought to be due to another planet colliding with the early Earth, causing an extraordinary giant impact, and in the process, forming the Moon. But, analysing chemicals in Apollo's rock samples has revealed that the Moon could be much more similar to Earth itself than any potential impactor. Geochemist Professor Alex Halliday of the University of Oxford, and Dr Jeff Andrews-Hanna, Colorado School of Mines – who is analysing the results from Nasa's Gravity Recovery and Interior Laboratory (GRAIL) lunar mission – discuss the theories and evidence to-date.

Are we Going Back? Settling the question of the Moon's origin seems likely to require more data – which, in turn, requires more missions. BBC Science correspondent Jonathan Amos tells us about the rationale and future prospects for a return to the Moon, including the Google Lunar XPrize.

As the Moon's commercial prospects are considered, who controls conservation of our only natural satellite? If commerce is driving a return to the Moon, who owns any resources that may be found in the lunar regolith? Dr Saskia Vermeylen of the Environment Centre at Lancaster University is researching the legality of claiming this extra-terrestrial frontier.

(Photo: Presenter Lucie Green. BBC copyright)

Trauma at War Nov 03, 2014

Show notes

They call them 'The Unexpected Survivors'. The casualties from the war in Afghanistan whose injuries were so severe that they were not expected to survive, but who survived nevertheless. In October, after 13 years Britain and the United States officially brought their combat operations in Helmand Afghanistan to an end. Camp Bastion, the coalition stronghold – once one of the largest military bases in the world – has been dismantled leaving a handful of buildings that will now be handed over to the Afghan National Army.

First established eight years ago in 2006, Camp Bastion came to host to one of the most extraordinary and successful trauma medical systems ever seen. Amongst the medics that went to and served in Afghanistan were doctors who trained with me in civilian hospitals. With the mission nearly at an end I had to see them and their system for myself, to try and understand just how it came to be and why it worked so well.

Photo courtesy of Ministry of Defence

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