Coronavirus (COVID-19) Q&A

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Coronavirus Disease 2019 (COVID-19) Update: How the VA Is Preparing Mar 25, 2020

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As COVID-19 spreads, clinicians and health systems are struggling to prepare for a surge of patients. Richard Stone, MD, the US Veterans Health Administration's Executive in Charge, spoke with JAMA about how the VA health system is preparing for this public health emergency.

Coronavirus (COVID-19) Update: Lessons Learned From The 2003 SARS Outbreak Mar 25, 2020

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In 2003, Toronto was the North American center for Severe Acute Respiratory Syndrome (SARS). The disease spread through the city's hospitals before anyone knew what was happening. Dr Allison McGeer was a clinician caring for SARS patients and ultimately was infected herself. She describes her experience as a patient and provider and reviews lessons learned that might help others manage their regional COVID-19 outbreaks.

Supporting the Health Care Workforce During the COVID-19 Global Epidemic

Coronavirus in New York - Report From the Front Lines Mar 24, 2020

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The ARDS in COVID-19 patients appears more responsive to PEEP and prone ventilation, but seems to require prolonged ventilation and may be associated with myocardial injury. Michelle N. Gong, MD, MS, Chief of Critical Care Medicine at Montefiore Medical Center in the Bronx, discusses her department's experience managing critically ill coronavirus patients, procuring diagnostic tests and personal protective equipment (PPE) for her staff, and more.

Coronavirus (COVID-19) Update: Chloroquine/Hydroxychloroquine and Azithromycin Mar 24, 2020

Show notes

Chloroquine was shown in 2004 to be active in vitro against SARS coronavirus but is of unproven efficacy and safety in patients infected with SARS-CoV-2. The drug's potential benefits and risks for COVID-19 patients, without and with azithromycin, is discussed by Dr. David Juurlink, head of the Division of Clinical Pharmacology and Toxicology at Sunnybrook Health Sciences Centre in Toronto.

Coronavirus Disease 2019 (COVID-19) Mitigation: Preparing Hospitals and Health Systems Mar 20, 2020

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The strategy for managing the COVID-19 pandemic has shifted from containment to mitigation. What does that mean for US hospitals and health systems? Kaiser Permanente Executive Vice President Stephen M. Parodi, MD, discusses telemedicine, protecting health care workers, equipment allocation planning, and more.

Practical Aspects of Otolaryngologic Clinical Services During the COVID-19 Epidemic Mar 20, 2020

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Interview with Jason Ying Kuen Chan, MBBS, author of Practical Aspects of Otolaryngologic Clinical Services During the 2019 Novel Coronavirus Epidemic: An Experience in Hong Kong

Coronavirus (COVID-19) Update: Early Safety Signals Around Ibuprofen and Renin-Angiotensin Inhibitors Mar 20, 2020

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Emerging information about how SARS-CoV-2 virus infects cells has led to speculation that NSAIDs and ACE inhibitors/angiotensin receptor blockers (ARBs) may worsen clinical disease. Infectious disease physician Carlos del Rio, MD, of Emory University explains the concerns and their clinical implications.

COVID-19 Update with NIAID's Anthony Fauci, MD; March 18, 2020 Mar 19, 2020

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Diagnostic testing, NSAIDs, ACE Inhibitors, antivirals, and more. Anthony Fauci, MD from NIAID discusses latest developments in the spread and clinical management of COVID-19 and the SARS-CoV-2 virus with JAMA Editor Howard Bauchner, MD.

JAMA Coronavirus Resource Center

Coronavirus Testing – March 16 Q&A with the CDC's Jay Butler, MD Mar 17, 2020

Show notes

Coronavirus testing will help countries manage coronavirus disease 2019 (COVID-19) but will raise questions about how to counsel patients about their test results. The CDC's Deputy Director for Infectious Diseases Jay C. Butler, MD, talks with JAMA Editor Howard Bauchner about what to advise healthy patients with positive PCR results, sick patients with negative test results, exposed health care workers, and more.

COVID-19 in Seattle: Clinical Features and Managing the Outbreak Mar 16, 2020

Show notes

Seattle has been a focal point for the US in the coronavirus pandemic. Doug Paauw, MD, professor of medicine at the University of Washington, in Seattle, describes the UW primary care clinic experience as this pandemic evolved. Major lessons learned included accommodating for significant numbers of staff not available to work in the clinic because of school closures, change in workflow because of shortages of personal protective equipment, physicians having to accommodate very large numbers of patient queries via telephone, email, or electronic health record, and the importance of the rapid development of local ability to test for SARS-CoV-2 independent of public health agencies.

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