Coronavirus (COVID-19) Q&A

Association of New-Onset Seizures With SARS-CoV-2 Vaccines Apr 29, 2024

Interview with Churl-Su Kwon, MD, MPH, author of Association of New-Onset Seizures With SARS-CoV-2 Vaccines: A Systematic Review and Meta-Analysis of Randomized Clinical Trials. Hosted by Cynthia E. Armand, MD. Related Content:

Association of New-Onset Seizures With SARS-CoV-2 Vaccines

Measuring Medicaid Enrollment More Accurately to Guide Post–COVID-19 Pandemic Policy Apr 05, 2024

Benjamin D. Sommers, MD, PhD, of Harvard University, speaks with JAMA Health Forum Editor John Ayanian, MD, MPP, and Deputy Editor Melinda Buntin, PhD, about differences in Medicaid enrollment as measured in surveys and administrative data. These differences have implications for estimating coverage now that the federal policy of continuous Medicaid eligibility during the COVID-19 pandemic has ended. Related Content:

Survey-Reported Coverage in 2019-2022 and Implications for Unwinding Medicaid Continuous Eligibility

February 2024 Medical News Summary Mar 01, 2024

Rural Maternity Care Is in Crisis—Here’s What Could Help; Type and Severity of Immunodeficiency Affect Speed of SARS-CoV-2 Clearance, Study Finds Related Content:

Evaluating the Effectiveness of Bivalent COVID-19 Vaccines in Children and Adolescents Feb 06, 2024

Bivalent mRNA COVID-19 vaccines were recommended for children and adolescents aged 5 to 17 years in the US, but were they effective? JAMA Associate Editor Tracy A. Lieu, MD, MPH, spoke with author Leora R. Feldstein, PhD, US Centers for Disease Control and Prevention, about the effectiveness of bivalent COVID-19 vaccines in children and adolescents. Related Content:

Effectiveness of Bivalent mRNA COVID-19 Vaccines in Preventing SARS-CoV-2 Infection in Children and Adolescents Aged 5 to 17 Years

Changes in Access to Care and Preventive Services by Race and Ethnicity During the COVID-19 Pandemic Feb 02, 2024

The COVID-19 pandemic has caused major disruptions in ambulatory care. In this interview with JAMA Health Forum Editor John Ayanian, MD, MPP, and Deputy Editor Melinda Buntin, PhD, Rishi K. Wadhera, MD, MPP, MPhil, of Harvard Medical School discusses how access to care and preventive services changed for different racial and ethnic groups in the US from 2019 to 2022. Related Content:

Changes in Health Care Access and Preventive Health Screenings by Race and Ethnicity

Safety and Effectiveness of Maternal and Child COVID-19 Vaccination Jan 22, 2024

Two recent studies find that COVID-19 vaccination during pregnancy is safe for infants and effective for children aged 1-4 years. JAMA Pediatrics Editor in Chief Dimitri Christakis, MD, and JAMA Pediatrics Associate Editor Alison Galbraith, MD, discuss clinical and policy implications with Grace Lee, MD, MPH, professor of Pediatrics at Stanford University School of Medicine, Palo Alto, California. Related Content:

The Connection Between SARS-CoV-2 and Type 1 Diabetes Risk in Young Children Sep 26, 2023

During the COVID-19 pandemic, the incidence of diabetes in childhood increased. JAMA Associate Editor Anne R. Cappola, MD, ScM, and Ezio Bonifacio, PhD, from the Center for Regenerative Therapies at the Dresden University of Technology, discuss SARS-CoV-2 infection and its association with islet autoimmunity in early childhood. Related Content:

SARS-CoV-2 Infection and Development of Islet Autoimmunity in Early Childhood

Efficacy of Gabapentin For Post–COVID-19 Olfactory Dysfunction Sep 21, 2023

Interview with Jay F. Piccirillo, MD, author of Efficacy of Gabapentin For Post–COVID-19 Olfactory Dysfunction: The GRACE Randomized Clinical Trial. Hosted by Paul C. Bryson, MD, MBA. Related Content:

Efficacy of Gabapentin For Post–COVID-19 Olfactory Dysfunction

Innovative Approach to Promote Equitable Access to COVID-19 Preventive Therapy Sep 01, 2023

In this interview, JAMA Health Forum Editor John Ayanian, MD, MPP, and Deputy Editor Melinda Buntin, PhD, explore with Erin K. McCreary, PharmD, and Atheendar S. Venkataramani, MD, PhD, how a large regional health system used a weighted lottery and intensive outreach to provide high-risk individuals in disadvantaged communities more equitable access to scarce monoclonal antibodies for preventing COVID-19. Related Content:

How Safe Were Kids in School During Phases of the Pandemic? Aug 04, 2023

JAMA Health Forum Editor John Ayanian, MD, and Deputy Editor Melinda Buntin, PhD, discuss with Sandra B. Nelson, MD (Massachusetts General Hospital, Boston), her JAMA Health Forum study of transmission of SARS-CoV-2 in schools in Massachusetts during 2 different phases of the COVID-19 pandemic. She found transmission rates were very low but varied by district and the availability of vaccines. Related Content:

Prevalence and Risk Factors for School-Associated Transmission of SARS-CoV-2

Risk of New Retinal Vascular Occlusion After mRNA COVID-19 Vaccination Apr 13, 2023

Interview with Rishi P. Singh, MD, author of Risk of New Retinal Vascular Occlusion After mRNA COVID-19 Vaccination Within Aggregated Electronic Health Record Data. Hosted by Neil Bressler, MD. Related Content:

Risk of New Retinal Vascular Occlusion After mRNA COVID-19 Vaccination Within Aggregated Electronic Health Record Data

Use of Mental Health Services During the COVID-19 Pandemic Jan 06, 2023

The COVID-19 pandemic has disrupted health care in many domains, including mental health services. JAMA Health Forum Editor John Ayanian, MD, MPP, and Deputy Editor Melinda Buntin, PhD, discuss with Ryan K. McBain, PhD, MPH, of RAND Corporation how the use of mental health care—both in-person and telehealth visits—changed for commercially insured adults during the first year of the COVID-19 pandemic in 2020.

Use of Cardiopulmonary Exercise Testing to Evaluate Long COVID-19 Symptoms in Adults Oct 12, 2022

Interview with Matthew S. Durstenfeld, MD, MAS, and Priscilla Y. Hsue, MD, authors of Use of Cardiopulmonary Exercise Testing to Evaluate Long COVID-19 Symptoms in Adults: A Systematic Review and Meta-analysis. Hosted by Angel N. Desai, MD, MPH. Related Content:

Use of Cardiopulmonary Exercise Testing to Evaluate Long COVID-19 Symptoms in Adults

Global COVID-19 Update Oct 05, 2022

In July 2022, Nahid Bhadelia, MD, MALD, joined the White House COVID-19 Response Team as senior policy advisor for Global COVID Response. The infectious disease physician, who is on sabbatical from Boston University, spoke with JAMA Associate Managing News Editor Jennifer Abbasi about the pandemic’s true burden of disease in low- and middle-income countries and ongoing COVID-19 vaccine inequity.

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Receipt of Out-of-State Telemedicine Visits Among Medicare Beneficiaries During the COVID-19 Pandemic Sep 16, 2022

Early in the COVID-19 pandemic, most states approved temporary regulatory changes so out-of-state physicians could provide telemedicine services to residents. Ateev Mehrotra, MD, of Harvard Medical School, and Chad Ellimoottil, MD, MS, of the University of Michigan, speak with JAMA Health Forum Editor John Ayanian, MD, and Deputy Editor Melinda Buntin, PhD, about the features of telemedicine visits provided for Medicare beneficiaries across state borders during the first year of the pandemic and potential policy changes that would enable such visits to continue. Related Content:

Long COVID: The US Federal Response Aug 03, 2022

On August 3, 2022, the US Department of Health and Human Services released 2 major reports in response to a presidential memo calling for a whole-of-government response to the SARS-CoV-2 sequelae known as “Long COVID." JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, discusses these new reports and the research and support needed to address this pervasive health concern with HHS Assistant Secretary for Health Rachel Levine, MD. Recorded July 29, 2022.

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Childcare Stress and Professional Outcomes Among US Health Care Workers During COVID-19 Jul 18, 2022

Interview with Elizabeth M. Harry, author of Childcare Stress, Burnout, and Intent to Reduce Hours or Leave the Job During the COVID-19 Pandemic Among US Health Care Workers.Hosted by Angel N. Desai, MD, MPH.

Global Association of COVID-19 Pandemic Measures With Cancer Screening Jul 07, 2022

Interview with Paolo Boffetta, MD, author of Global Association of COVID-19 Pandemic Measures With Cancer Screening: A Systematic Review and Meta-analysis. Hosted by Jack West, MD.

May 2022 Medical News Summary May 24, 2022

What a Post–Roe v Wade US Might Look Like for Physicians; SARS-CoV-2 RNA Can Persist in Stool Months After Respiratory Tract Clears Virus

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Q&A With White House COVID-19 Response Coordinator Ashish Jha May 18, 2022

As the White House’s COVID-19 Response Coordinator, Ashish Jha, MD, MPH, plays a critical role in the federal government’s continued response to the pandemic. In this Q&A with JAMA Associate Editor Preeti Malani, MD, Jha details current thinking and federal planning around additional boosters, testing trends, and treatment for COVID-19.

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Neuropsychiatric Ramifications of Severe COVID-19 and Other Severe Acute Respiratory Infections May 11, 2022

Interview with Peter Watkinson, MD, and Julia Hippisley-Cox, MD, authors of Neuropsychiatric Ramifications of Severe COVID-19 and Other Severe Acute Respiratory Infections. Hosted by John Torous, MD, MBI.

Reducing “COVID-19 Misinformation” While Preserving Free Speech Apr 19, 2022

Misinformation about COVID-19 (such as around vaccines, masks, and ineffective drugs) has circulated widely during the pandemic, and much of this misinformation is protected by the Free Speech Clause of the First Amendment. Professor of Surgery and Perioperative Care and Professor of Law William M. Sage, MD, JD, from the University of Texas at Austin, is interviewed in this JAMA podcast.

Postmortem Assessment of Olfactory Tissue Degeneration and Microvasculopathy in Patients With COVID-19 Apr 11, 2022

Interview with Cheng-Ying Ho, MD, PhD, author of Postmortem Assessment of Olfactory Tissue Degeneration and Microvasculopathy in Patients With COVID-19. Hosted by Cynthia E. Armand, MD.

Health Care Job Loss During the Pandemic Apr 08, 2022

The health care workforce has yet to recover from the COVID-19 pandemic, and there is a concerning trend of increasing numbers of physicians leaving the workforce. JAMA Health Forum Editor John Ayanian, MD, MPP, and Deputy Editor Melinda Buntin, PhD, discuss with Bianca Frogner, PhD, of the University of Washington new findings that show how all segments of the health care workforce have struggled, with more pronounced effects among long-term care workers, aides, assistants, workers with young children, and workers of color.

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Association of COVID-19 Quarantine Duration and Postquarantine Transmission Risk in 4 University Cohorts Feb 25, 2022

Interview with Michael Springer, PhD, and Andrew Bo Liu, authors of Association of COVID-19 Quarantine Duration and Postquarantine Transmission Risk in 4 University Cohorts Hosted by Angel N. Desai, MD, MPH.

Association Between COVID-19 Vaccine and Sudden Sensorineural Hearing Loss Feb 24, 2022

Interview with Ilana Doweck, MD, author of Association Between the BNT162b2 Messenger RNA COVID-19 Vaccine and the Risk of Sudden Sensorineural Hearing Loss, and Eric J. Formeister, MD, MS, author of Assessment of Sudden Sensorineural Hearing Loss After COVID-19 Vaccination Hosted by Joseph P. Bradley, MD.

COVID-19 and Pregnancy: Disease Outcomes and Prevention With Vaccination Feb 22, 2022

Pregnant and recently pregnant individuals who become infected with the COVID-19 virus are at high risk of requiring extra medical care. JAMA Associate Editor Linda Brubaker, MD, MS, from University of California San Diego discusses the rapidly evolving data around COVID-19 and vaccine effectiveness and safety as it relates to pregnancy, breastfeeding, and fertility with 3 experts in the field: Laura E. Riley, MD, from Weill Cornell Medicine, Christina Chambers, PhD, MPH, from University of California San Diego School of Medicine-Pediatrics, and Denise Jamieson, MD, MPH, from Emory University.

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Conflict of Interest Disclosures:

Dr Chambers reported receiving research funding from Pfizer-BioNTech to study the safety of its COVID-19 vaccine in pregnancy.

Dr Jamieson reported no disclosures.

Dr Riley reported receiving compensation from UpToDate for work on several infections disease cards, receiving royalties from Turner Publishing, and serving on an advisory board for Maven. Dr Riley also reported serving on a CDC Advisory Committee on Immunization Practices workgroup on COVID-19 vaccines and vaccine safety and workgroups for the American College of Obstetricians and Gynecologists and Society for Maternal-Fetal Medicine of COVID-19 vaccination, without compensation.

Medicaid Policy Associated With Increased Enrollment During the Pandemic Feb 04, 2022

For the duration of the COVID-19 pandemic public health emergency, state Medicaid programs elected to maintain eligibility for Medicaid recipients in exchange for increased federal funding. In this podcast, Dr Laura Dague of the Bush School of Government & Public Service at Texas A&M University discusses her JAMA Health Forum article finding that this policy was associated with the higher Medicaid enrollment seen during the pandemic. JAMA Health Forum Editor John Ayanian and Deputy Editor Melinda Buntin discuss the policy implications of this work with Dr Dague and other recent articles touching on Medicaid enrollment.

Medicaid Disenrollment After the COVID-19 Pandemic

Medicaid Coverage Disruptions Among Children Enrolled in North Carolina Medicaid, 2016-2018

Association of Medicaid Expansion in Arkansas With Postpartum Coverage, Outpatient Care, and Racial Disparities

At-Home Self-Testing Kits for SARS-CoV-2 Jan 31, 2022

Interview with Steven Woloshin, MD, MS, author of At-Home Self-Testing Kits for SARS-CoV-2: A Randomized Trial Assessing How Consumers Interpret and Act on Possible Test Results. Hosted by Deborah Grady, MD, MPH.

Association of Child Masking With COVID-19 Childcare Program Closures Jan 27, 2022

Interview with Walter S. Gilliam, PhD, and Thomas S. Murray, MD, PhD, authors of Association of Child Masking With COVID-19–Related Closures in US Childcare Programs. Hosted by Angel Desai, MD.

Public Health in an Era of Endemic COVID-19 Jan 18, 2022

Three members of President Biden’s former COVID-19 Advisory Board—Luciana Borio, MD, Ezekiel Emanuel, MD, PhD, and Mike Osterholm, PhD—discuss their recent JAMA Viewpoints, providing their ideas on strategies for public health as COVID-19 transitions from pandemic to endemic. Hosted by JAMA Associate Editor Preeti Malani, MD.

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COVID-19 CDC Update – Early January 2022 Jan 11, 2022

Former CDC Executive Secretariat of the Advisory Committee on Immunization Practices Amanda Cohn, MD, joins JAMA Associate Editor Preeti Malani, MD, for the latest on the need for vaccination and boosters, vaccine misinformation, and tackling the pandemic from a global perspective. Recorded January 6, 2022.

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COVID-19 Update: Omicron Variant Dec 06, 2021

Infectious disease experts Adam Lauring, MD, PhD, and Carlos del Rio, MD, join JAMA Associate Editor Preeti Malani, MD, MSJ, for a discussion of the newly emerged Omicron variant, the potential for a 2021-2022 "twindemic" with flu, and the latest COVID-19 clinical updates. Recorded December 1, 2021.

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Efficacy of Therapeutic-Dose Heparin for Thromboprophylaxis in Hospitalized Patients With COVID-19 Oct 07, 2021

Interview with Alex C. Spyropoulos, author of Efficacy and Safety of Therapeutic-Dose Heparin vs Standard Prophylactic or Intermediate-Dose Heparins for Thromboprophylaxis in High-risk Hospitalized Patients With COVID-19: The HEP-COVID Randomized Clinical Trial

A New Vision for Nursing Homes Oct 06, 2021

The longstanding shortcomings of the US nursing home model became more visible during the COVID-19 crisis. Terry Fulmer, PhD, RN, a geriatric nurse practitioner and president of the John A. Hartford Foundation in New York City, discusses the challenges skilled nursing facilities face and shares her vision for nursing homes that better serve residents and support the workforce.

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COVID-19 in Canada—Experience and Response to Waves 2 and 3 Sep 28, 2021

Canadian law gives the country’s individual provinces and territories primary responsibility for coronavirus containment and mitigation. JAMA Associate Editor Preeti Malani, MD, MSJ, from the University of Michigan and Allan S. Detsky, MD, PhD, from the University of Toronto, Ontario, Canada, discuss the national pandemic experience, including public health responses to infection and vaccine allocation, from fall 2020 through summer 2021.

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COVID-19 in Canada: Experience and Response to Waves 2 and 3

Delivery of Ophthalmic Telemedicine During the COVID-19 Pandemic Sep 23, 2021

Interview with Grayson W. Armstrong, MD, MPH, author of Association of Patient Characteristics With Delivery of Ophthalmic Telemedicine During the COVID-19 Pandemic, and Fasika Ambachew Woreta, MD, MPH, author of Analysis of Sex Diversity Trends Among Ophthalmology Match Applicants, Residents, and Clinical Faculty

Rebounding From COVID-19’s Reversal of Recent Progress in the ICU Sep 15, 2021

Many patients experience neurocognitive deficits, PTSD, and generalized weakness and disability following an intensive care unit (ICU) stay. JAMA Medical News Senior Writer Rita Rubin talks with E. Wesley Ely, MD, MPH, a professor of medicine at Vanderbilt University School of Medicine, about ICU aftereffects, post-acute COVID-19 syndrome, and how the coronavirus pandemic, particularly hospitals’ restrictions on visitors, impeded progress made since the 1990s in caring for the critically ill.

New Evidence on the Effects of the COVID-19 Pandemic on Health Insurance Coverage Sep 03, 2021

We know that the pandemic caused millions of people to lose their jobs, and potentially their job-based insurance, and yet new survey data showed surprisingly small changes in uninsurance rates at the end of 2020. Kate Bundorf, PhD, from the Sanford School of Public Policy at Duke University and Jessica Banthin, PhD, of the Urban Institute talk to JAMA Health Forum Deputy Editor Melinda Buntin about these trends and the role played by Medicaid and exchange coverage. JAMA Health Forum Editor John Ayanian and Melinda Buntin also discuss other recent work about health insurance coverage and the ACA that has appeared in JAMA Health Forum.

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Quantifying Particle Aerosolization Risk During Tracheostomy Surgery and Tracheostomy Care Jul 22, 2021

Interview with Alexander T. Hillel, M.D., author of Quantifying Viral Particle Aerosolization Risk During Tracheostomy Surgery and Tracheostomy Care

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Safety Recommendations for Evaluation and Surgery of the Head and Neck During the COVID-19 Pandemic

COVID-19’s Shock to Health Care Services Jul 06, 2021

The COVID-19 pandemic has had far-reaching effects on the use of health care services. Dr Nora Becker of the University of Michigan talks about her research on reductions in the use of women’s preventive health services, and JAMA Health Forum Editors Dr John Ayanian and Dr Melinda Buntin discuss other JAMA Health Forum pieces on the effects of state “reopenings” on COVID-19 hospitalizations and deaths, the effects of day care closures on women’s participation in the labor force, and news about nursing home outbreaks of COVID-19.

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Lung Transplants for COVID-19—The Option of Last Resort Jun 17, 2021

Lung transplantation has become an option of last resort for a small subset of patients with COVID-19-related acute respiratory distress syndrome (ARDS) or pulmonary fibrosis. Ankit Bharat, MD, chief of Thoracic Surgery and director of Lung Transplant and ECMO at Northwestern Memorial Hospital in Chicago, discusses his experience performing lung transplants for patients with respiratory failure due to COVID-19, including the first successful double lung transplant in the US for a patient with COVID-19-related ARDS.

May 2021 Medical News Summary May 25, 2021

Researchers Tie Severe Immunosuppression to Chronic COVID-19 and Virus Variants; An Inside Look at a Post–COVID-19 Clinic; COVID-19 and the “Lost Year” for Smokers Trying to Quit

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An Inside Look at a Post–COVID-19 Clinic May 05, 2021

COVID-19 leaves some people with a troubling constellation of symptoms that has been known as long-haul COVID but now has a more formal name: postacute sequelae of SARS-CoV-2 infection (PASC). Currently, 33 states in the US have at least 1 clinic dedicated to caring for patients with PASC. Aluko Hope, MD, a pulmonary and critical care physician, cofounded the Montefiore-Einstein COVID-19 Recovery Clinic in New York in 2020. Now the medical director of the Long Covid-19 Program at the Oregon Health & Sciences University, Dr Hope provides insight into the care provided at a post-COVID-19 clinic.

Noninvasive Ventilation of COVID-19 Patients Mar 29, 2021

Noninvasive ventilation (NIV) may help COVID-19 patients in respiratory failure avoid invasive mechanical ventilation but may also lead to delays in intubation with potential for worse clinical outcomes.

Domenico L. Grieco, MD, of Fondazione Policlinico Agostino Gemelli IRCCS in Rome, Jesse B. Hall, MD, of the University of Chicago, and Laveena Munshi, MD, MSc, of Sinai Health System/University Health Network of the University of Toronto join JAMA's live Q&A series to discuss helmet NIV, high-flow nasal oxygen, and other NIV modalities in the management of hypoxic coronavirus patients. Recorded March 25, 2021.

Respiratory Support During the COVID-19 Pandemic: Is It Time to Consider Using a Helmet?

Noninvasive Ventilation of COVID-19 Patients

March 2021 Medical News Summary Mar 23, 2021

The Price of Success—How to Evaluate COVID-19 Vaccines When They’re Available Outside of Clinical Trials; When the Human Voice Speaks Volumes About Lung Function; COVID-19 Vaccines vs Variants—Determining How Much Immunity Is Enough

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Coronavirus Variants With John P. Moore Mar 08, 2021

Genetic variants of the SARS-CoV-2 virus are emerging but so far do not seem to have caused breakthrough infections in people with previous infection or in those who have been vaccinated. John P. Moore, PhD, of Weill Medical College of Cornell University in New York, joins JAMA's Q&A series for an update on the latest variants and what you need to know. Recorded March 4, 2021.

Will COVID-19 Become a Recurrent Seasonal Disease? Mar 03, 2021

Interview with Christopher J.L. Murray, MD, DPhil, author of The Potential Future of the COVID-19 Pandemic: Will SARS-CoV-2 Become a Recurrent Seasonal Infection?

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The Potential Future of the COVID-19 Pandemic

Funding of Pharmaceutical Innovation During and After the COVID-19 Pandemic Mar 02, 2021

Interview with James C. Robinson, PhD, author of Funding of Pharmaceutical Innovation During and After the COVID-19 Pandemic

Coronavirus Vaccine Update From the CDC With Nancy E. Messonnier, MD Mar 02, 2021

Nancy E. Messonnier, MD is director of the National Center for Immunization and Respiratory Diseases (NCIRD) at the Centers for Disease Control and Prevention (CDC) and leads the CDC’s efforts on COVID-19 vaccination. She joins JAMA's Q&A series to discuss the agency's response to emerging coronavirus variants, the FDA advisory hearings on the new Johnson & Johnson vaccine, and other agency activities and priorities related to COVID-19 control. Recorded February 26, 2021.

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Coronavirus Vaccines—An Overview Feb 26, 2021

The Pfizer-BioNTech and Moderna COVID-19 mRNA vaccines are the first of many being tested for widespread use. Buddy Creech, MD, MPH, director of the Vanderbilt Vaccine Research Program, reviews these and other vaccines likely to become available, including products that use inactivated, protein subunit, and viral vector immunization strategies.

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SARS-CoV-2 Vaccines

Vaccinating Nursing Home and Long-term Care Facility Residents for Coronavirus Feb 24, 2021

The CDC coordinated a massive effort to immunize nearly all nursing home and long-term care facility residents in the US against COVID-19 infection in the month after vaccine approval. Ruth Link-Gelles, PhD, MPH, CDC staff epidemiologist and Lieutenant Commander of the US Public Health Service Commissioned Corps, describes how.

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February 2021 Medical News Summary Feb 23, 2021

Researchers Investigate What COVID-19 Does to the Heart; “Important Conversations” Are Needed to Explain the Nocebo Effect; Therapists Donate Their Time to Counsel Distressed Health Care Workers

“Important Conversations” Are Needed to Explain the Nocebo Effect

Therapists Donate Their Time to Counsel Distressed Health Care Workers

Coronavirus Update With CDC Director Rochelle Walensky - February 17, 2021 Feb 19, 2021

CDC Director Rochelle P. Walensky, MD, MPH, returns to JAMA's Q&A series to discuss the agency's response to emerging SARS-CoV-2 variants, implications for the planned vaccine mobilization strategy, the upcoming Johnson & Johnson vaccine FDA advisory hearings, strategies for reopening K-12 schools, and other agency activities and priorities related to COVID-19 control. Recorded February 17, 2021.

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Coronavirus Vaccine Update With Paul Offit – February 11, 2021 Feb 15, 2021

Paul A. Offit, MD, of The Children's Hospital of Philadelphia returns to JAMA's Q&A series to provide an update on the emergence of COVID-19 variants and their implications for vaccine development, including the Johnson & Johnson vaccine, scheduled for a US Food and Drug Administration VRBPAC hearing on February 26, 2021. Recorded February 11, 2021.

Mask Wearing for COVID-19 Prevention—Summary of CDC Data Feb 10, 2021

Natural experiments comparing coronavirus spread on ships and in hair salons with vs without face masks point to the importance of wearing masks for curbing SARS-CoV-2 spread. John T. Brooks, MD, chief medical officer of the CDC’s COVID-19 response team, reviews recently published epidemiologic data that reinforce the role of mask use for pandemic control.

Coronavirus Vaccination in Pregnant and Breastfeeding Individuals Feb 10, 2021

As US vaccine distribution expands to include younger healthier populations, questions about vaccine safety in women of childbearing age have become more urgent. University of Texas Southwestern Medical Center's Catherine Y. Spong, MD, and Emory University School of Medicine's Denise J. Jamieson, MD, MPH, both eminent obstetrician/gynecologists, join JAMA's Q&A series to discuss the safety of the Pfizer-BioNTech and Moderna vaccines in pregnant and nursing mothers, and in individuals trying to get pregnant. Recorded February 8, 2021.

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Genetic Variants of SARS-CoV-2—What Do They Mean?

Coronavirus Update With Anthony Fauci – February 3, 2021 Feb 05, 2021

NIAID Director Anthony S. Fauci, MD, returns to JAMA's Q&A series to discuss

Shifts in the US pandemic response under the Biden administration
Emerging genetic variants and implications for vaccine efficacy
Prospects for new vaccine approvals and more.

Mental Health, Overdose, and Violence Outcomes and the COVID-19 Pandemic Feb 03, 2021

Interview with Kristin M. Holland, PhD, MPH, author of Trends in US Emergency Department Visits for Mental Health, Overdose, and Violence Outcomes Before and During the COVID-19 Pandemic

Coronavirus Update With Peter Piot, MD, PhD Feb 01, 2021

Peter Piot, MD, PhD, director of The London School of Hygiene and Tropical Medicine, is a legend in global health, having been involved in identification of HIV and Ebola virus in Africa. He was founding executive director of UNAIDS and Under Secretary-General of the United Nations from 1995 to 2008. He joins JAMA's Q&A series to discuss the global public health response to COVID-19 past, present, and future. Recorded January 28, 2021.

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The Challenges Ahead With Monoclonal Antibodies

Association of Psychiatric Disorders With Mortality Among Patients With COVID-19 Jan 27, 2021

Interview with Donald C. Goff, MD, author of Association of Psychiatric Disorders With Mortality Among Patients With COVID-19

Racial and Ethnic Disparities in COVID-19 Jan 22, 2021

Ethnic and racial minorities have been particularly hard hit with COVID-19 in some communities. Mitchell Katz, MD, president and chief executive officer of New York City Health + Hospitals, and former Los Angeles County health agency director, discusses this problem and what has been learned from COVID-19 that can help resolve the general problem of health care disparities.

Coronavirus Vaccine Update with Paul Offit and Robert Wachter Jan 21, 2021

To get more vaccine to more people more efficiently, UCSF School of Medicine's Robert M. Wachter, MD, recently urged giving a single dose now and deferring the second dose until more vaccine is available. Paul A. Offit, MD, of The Children's Hospital of Philadelphia, disagrees. The two discuss the pros and the cons of the plan and alternative responses to road bumps in the US vaccine rollout, on JAMA's live Q&A series. Recorded January 19, 2021.

Coronavirus Update With CDC Director Rochelle Walensky Jan 21, 2021

Incoming Centers for Disease Control and Prevention (CDC) Director Rochelle P. Walensky, MD, MPH, returns to JAMA's Q&A series to discuss her vision and priorities for the agency and changes in its pandemic response strategies, when she takes the reins on January 20. Recorded January 19, 2021.

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All-Cause Excess Mortality and COVID-19–Related Mortality Among US Adults Aged 25-44 Years, March-July 2020

Asymptomatic SARS-CoV-2 Transmission; Association of ICU Volume with Patient Mortality During the COVID-19 Pandemic Jan 19, 2021

Editor in Chief Fred Rivara and Deputy Editor Steve Fihn discuss research published in JAMA Network Open in January 2021

SARS-CoV-2 Transmission From People Without COVID-19 Symptoms

Intensive Care Unit Strain and Mortality Risk Among Critically Ill Patients With COVID-19—There Is No “Me” in COVID

The Winter COVID-19 Surge in New York and Los Angeles Jan 15, 2021

Mitchell Katz, MD, president and chief executive officer of New York City Health + Hospitals, and former Los Angeles County health agency director, discusses causes, similarities, and differences between the spike of COVID-19 cases, hospitalizations, and deaths in the 2 cities.

Coronavirus Critical Care Update With Lennie Derde and Christopher Seymour Jan 15, 2021

The COVID-19 pandemic has prompted scientists to use adaptive research designs to evaluate potential treatments simultaneously and efficiently, increasing the likelihood that patients will receive treatments most likely to be effective for them. Lennie Derde, MD, of University Medical Center Utrecht in the Netherlands and JAMA Associate Editor Christopher W. Seymour, MD, of University of Pittsburgh Medical Center join JAMA's Q&A series to discuss the latest in critical care management of COVID-19 patients and emerging treatment strategies and therapies. Recorded January 13, 2021.

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Sensible Medicine-Optimizing the Trade-off Between Learning and Doing in a Pandemic

An Opportune Time to Update Medical Licensing Jan 13, 2021

Interview with Samyukta Mullangi, MD, MBA, author of The COVID-19 Pandemic—An Opportune Time to Update Medical Licensing; also with Mitchell H. Katz, MD, chief executive officer of New York City Health and Hospitals and author of Modernize Medical Licensing, and Credentialing, Too—Lessons From the COVID-19 Pandemic

Coronavirus Vaccine Update With Arnold S. Monto, MD Jan 13, 2021

Arnold S. Monto, MD, chaired the US Food and Drug Administration's Vaccines and Related Biological Products Advisory Committee (VRBPAC) meetings in December that led to Emergency Use Authorization (EUA) of the Pfizer/BioNTech and Moderna vaccines. He joins JAMA's Q&A series from the University of Michigan School of Public Health to discuss experience to date with the 2 products and what's next in vaccine development. Recorded January 11, 2021.

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Experts Discuss COVID-19: Vaccine Allocation, Placebo Groups, and More

Using Lorenz Curves to Measure Racial Inequities in COVID-19 Testing Jan 12, 2021

Aaloke Mody, MD, joins JAMA Network Open Digital Media Editor, Seth Trueger, MD, MPH, to discuss a cross-sectional study that uses Lorenz curves as a metric for quantifying racial inequities in coronavirus disease 2019 (COVID-19) testing. Read the article here: https://ja.ma/2MOMjWG.

JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Understanding the New SARS-CoV-2 Mutation Found in England Jan 08, 2021

Gregory Armstrong, MD, director of the Advanced Molecular Detection Program for the CDC, explains what is currently known about the new mutations of SARS-CoV-2.

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Genetic Variants of SARS-CoV-2—What Do They Mean?

COVID-19 Vaccine Safety–Anaphylaxis and Allergic Reactions Jan 06, 2021

Tom Shimabukuro, MD, MPH, MBA, and Sara Mbaeyi, MD, MPH, from the CDC discuss rare allergic complications in patients who received the first dose of the Pfizer-BioNTech vaccine between December 14-23, 2020.

Understanding SARS-CoV-2 Genetic Variants Jan 06, 2021

Adam Lauring, MD, PhD, from the University of Michigan Division of Infectious Diseases, an expert on the evolutionary biology of RNA viruses, explains the new genetic variants recently found in SARS-CoV-2 and their importance.

Public Concern About Violence, Firearms, and the COVID-19 Pandemic in California Jan 05, 2021

Nicole Kravitz-Wirtz, PhD, MPH, joins JAMA Network Open Digital Media Editor, Seth Trueger, MD, MPH, to discuss a survey study describing individuals’ concerns regarding violence in the context of the coronavirus disease 2019 (COVID-19) pandemic, experiences of pandemic-related unfair treatment, prevalence of and reasons for firearm acquisition, and changes in firearm storage practices due to the pandemic. Read the article here: https://ja.ma/2X7lC1x.

JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Nursing Homes and COVID-19 Dec 30, 2020

Elderly persons and residents of nursing homes have been the hardest hit in the COVID-19 pandemic. Harvard geriatrician Sharon Inouye, MD, discusses the effect COVID-19 has had on nursing homes and what should be done about it.

COVID-19 Conspiracies and Beyond: How Physicians Can Deal With Patients’ Misinformation Dec 30, 2020

Communication science expert Brian Southwell, PhD, recently launched a training workshop at the Duke University School of Medicine to address a major clinical problem: What should physicians do when patients are misinformed about their health? It’s one of only a few such programs in the nation. Southwell, a scholar with the medical school’s Social Science Research Institute and a senior director at the independent, nonprofit research institute RTI International, chatted with JAMA Medical News Associate Managing Editor Jennifer Abbasi about the viral spread of false health information and malicious disinformation campaigns, why we’re vulnerable to falling for them, and how time-pressed physicians can deal with all the noise.

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COVID-19 Conspiracies and Beyond: How Physicians Can Deal With Patients’ Misinformation

US Public Attitudes Toward COVID-19 Vaccine Mandates Dec 22, 2020

Emily A. Largent, JD, PhD, RN, joins JAMA Network Open Digital Media Editor, Seth Trueger, MD, MPH, to discuss a survey study assessing the acceptability of coronavirus disease 2019 (COVID-19) vaccine mandates among members of the US public. Read the article here: https://ja.ma/3nGKAQP.

JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

COVID-19 Vaccines and Herd Immunity Dec 21, 2020

With coronavirus vaccines now available, what are the timeline and prospects for "herd immunity" and return to a new normal? Marc Lipsitch, DPhil, of Harvard T.H. Chan School of Public Health returns to JAMA's Q&A series with Paul D. Biddinger, MD, director of Massachusetts General Hospital's Center for Disaster Medicine, to discuss. Recorded December 17, 2020.

Coronavirus Vaccine FDA Update Dec 16, 2020

Peter W. Marks, MD, PhD, and Stephen M. Hahn, MD, return to JAMA's Q&A series to discuss the Pfizer/BioNTech and Moderna vaccines: the data, the weekend's EUA designation (Pfizer/BioNTech), and the process for future full licensure and postmarketing safety surveillance.

Dr Marks directs the US FDA's Center for Biologics Evaluation and Research (CBER). Dr Hahn is commissioner of the US Food and Drug Administration. Recorded December 14, 2020.

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Behaviorally Informed Strategies for a National COVID-19 Vaccine Promotion Program

Surgeon Creates Barrier-Free COVID-19 Testing Service for Philadelphia's Black Residents Dec 16, 2020

Ala Stanford, MD, founder of Philadelphia’s Black Doctors COVID-19 Consortium, talks with JAMA Medical News Staff Writer Mary Chris Jaklevic about her work to establish COVID-19 testing sites for the city’s Black residents.

Coronavirus Vaccine Update With Anthony Fauci Dec 15, 2020

Anthony S. Fauci, MD, returns to JAMA's Q&A series to discuss the Pfizer/BioNTech and Moderna vaccines: the public data, deliberations at Thursday's FDA Advisory Committee meeting, and prospects for an agency Emergency Use Authorization designation, licensure, and rollout. Recorded December 11, 2020.

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Coronavirus Infections—More Than Just the Common Cold

Parental Relationships with Children During COVID-19 Pandemic-Related Lockdowns Dec 15, 2020

JAMA Fishbein Fellow Kristin Walter, MD, interviews Craig Garfield, MD, and Richard Weissbourd, EdD, about parental relationships during the COVID-19 pandemic.

Comparison of Triage Scoring Guidelines for Allocation of Mechanical Ventilators Dec 15, 2020

Hannah Wunsch, MD, MSc, joins JAMA Network Open Digital Media Editor, Seth Trueger, MD, MPH, to discuss a cohort study comparing the New York State Ventilator Allocation Guideline with the original triage criteria proposed by White and Lo to determine which and how many admissions to US intensive care units are identified as having the lowest priority for ventilator allocation. Read the article here: https://ja.ma/37k0sTE.

Watch the JAMA Coronavirus Q&A with Douglas B. White, MD, MAS from March 27, 2020: https://edhub.ama-assn.org/jn-learning/video-player/18365657

JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

The COVID Tracking Project Dec 11, 2020

The COVID Tracking Project, launched by The Atlantic, collects and publishes data required to understand the COVID-19 outbreak in the US, including data on race and ethnicity needed to understand health inequities in the outbreak.

Atlantic Monthly journalists Alexis C. Madrigal and Erin Kissane join JAMA's Q&A series to describe the project and their experience developing a database for fact-based health reporting on the pandemic.

Recorded December 10, 2020.

Gyms, Restaurants, Mass Transit, and Community COVID-19 Exposures Dec 10, 2020

Lockdowns resulting from COVID-19 have had a devastating effect on everyone’s personal lives and the economy. What factors in people’s daily lives are most associated with SARS-CoV-2 transmission between people? Manish Patel, MD, team lead of the CDC’s Influenza Prevention & Control Team, discusses a study they conducted examining what sorts of activities might be associated with COVID-19 disease transmission.

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Community Outbreak Investigation of SARS-CoV-2 Transmission Among Bus Riders in Eastern China

Race/Ethnicity Among Children With COVID-19–Associated Multisystem Inflammatory Syndrome Dec 08, 2020

Ellen H. Lee, MD, joins JAMA Network Open Digital Media Editor, Seth Trueger, MD, MPH, to discuss a cohort study describing the distribution of race/ethnicity among cases of coronavirus disease 2019 (COVID-19)–associated multisystem inflammatory syndrome in children reported to the New York City Department of Health and Mental Hygiene. Read the article here: https://ja.ma/37vCJ1K.

JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open.

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Air Handling Standards for Increasing the Safety of Indoor Spaces During the COVID-19 Pandemic Dec 07, 2020

Closing businesses during the COVID-19 pandemic has had devastating consequences for individuals and the economy in general. Proper air handling combined with the use of masks and physical distancing can greatly improve the safety of indoor spaces. Joseph Allen, DSc, MPH, assistant professor of exposure assessment science at Harvard T.H. Chan School of Public Health, and Andrew Ibrahim, MD, assistant professor of surgery and architecture and urban planning at the University of Michigan, discuss air conditioning standards that can substantially reduce the risk of disease transmission in indoor spaces.

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Turbulent Gas Clouds and Respiratory Pathogen Emissions

Coronavirus Vaccine Update With Paul Offit Dec 04, 2020

With the Pfizer and Moderna coronavirus vaccines reportedly under review at the US FDA for Emergency Use Authorization (EUA), Paul A. Offit, MD, of the Children's Hospital of Philadelphia, returns to JAMA's Q&A series to provide an update on what to expect, prospects for vaccine rollout and distribution in the coming months, and ongoing safety surveillance. Recorded December 2, 2020.

Coronavirus Update with Nicholas Christakis Nov 25, 2020

Yale Sterling Professor Nicholas A. Christakis, MD, PhD, returns to JAMA's Q&A series to discuss the surge in US cases and other recent pandemic developments. Dr Christakis is author of the recently published book "Apollo's Arrow: The Profound and Enduring Impact of Coronavirus on the Way We Live." Recorded November 23, 2020.

Delirium in Older Patients With COVID-19 Presenting to the Emergency Department Nov 24, 2020

Maura Kennedy, MD, MPH, joins JAMA Network Open Digital Media Editor, Seth Trueger, MD, MPH, to discuss a cohort study examining how frequently older adults with coronavirus disease 2019 (COVID-19) present to the emergency department with delirium and their associated hospital outcomes. Read the article here: https://ja.ma/3q5h74S.

JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

COVID-19 Update—Critical Care and Pandemic Response Nov 23, 2020

In the midst of rising COVID-19 case rates globally, Derek C. Angus, MD, MPH, and Rochelle P. Walensky, MD, MPH, return to JAMA's Q&A series to update viewers on developments in the pandemic and the critical care management of COVID-19 patients. Dr Angus is Chief Health Care Innovation Officer at the University of Pittsburgh Medical Center, professor and chair of Critical Care Medicine, and a senior JAMA editor. Dr Walensky is Chief of Infectious Diseases at Massachusetts General Hospital and a professor at Harvard Medical School. Recorded November 19, 2020.

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Optimizing the Trade-off Between Learning and Doing in a Pandemic

Older Adults and the Mental Health Effects of COVID-19 Nov 20, 2020

Interview with Ipsit V. Vahia, MD, author of Older Adults and the Mental Health Effects of COVID-19

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Older Adults and the Mental Health Effects of COVID-19

Herd Immunity as a Coronavirus Pandemic Strategy Nov 11, 2020

Would letting coronavirus infect the broad US and global population be a safe and effective means of ending the COVID-19 pandemic? Jay Bhattacharya, MD, PhD, of Stanford University's Center for Primary Care and Outcomes Research is a signatory of the "Great Barrington Declaration," which proposes to "allow those at minimal risk of death to live their lives normally to build up immunity to the virus through natural infection, while better protecting those who are at highest risk." Marc Lipsitch, PhD, of the Harvard T.H. Chan School of Public Health, a signatory of the "John Snow Memorandum," which refutes the argument, responds.

Coronavirus and US State Departments of Health Nov 11, 2020

Ngozi O. Ezike, MD, director of the Illinois Department of Public Health, discusses state and regional management of the COVID-19 pandemic. Recorded November 9, 2020.

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Universal Masking in the United States

US Clinicians’ Experiences and Perspectives on Resources and Care During the COVID-19 Pandemic Nov 10, 2020

Catherine R. Butler, MD, MA joins JAMA Network Open Digital Media Editor, Seth Trueger, MD, MPH, to discuss a qualitative study describing the perspectives and experiences of clinicians involved in institutional planning for resource limitation and/or patient care during the coronavirus disease 2019 (COVID-19) pandemic.

Read the article here: https://ja.ma/32vBC0h.

JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Long-term Health Consequences of COVID-19 Nov 03, 2020

Interview with Carlos del Rio, MD, author of Long-term Health Consequences of COVID-19

Findings Associated With Severe Illness and Mortality Among Hospitalized Individuals With COVID-19 Nov 03, 2020

Roy H. Perlis, MD, MSc, joins JAMA Network Open Digital Media Editor, Seth Trueger, MD, MPH, to discuss a cohort study assessing admission laboratory and comorbidity features associated with critical illness and mortality risk among patients hospitalized with coronavirus disease 2019 (COVID-19) across 6 Eastern Massachusetts hospitals.

Read the article here: https://ja.ma/384dBkt. JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open.

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Should We Mandate a COVID-19 Vaccine for Children? Nov 02, 2020

JAMA Pediatrics Editors' Summary by Dimitri Christakis, MD, MPH, Editor in Chief, and Frederick Rivara, MD, MPH, Editor in Chief of JAMA Network Open for the November 2, 2020 issue.

The Effect of COVID-19 on the 2020-2021 Influenza Season Nov 02, 2020

Tim Uyeki, MD, chief medical officer for the Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention (CDC), discusses how the COVID-19 pandemic may affect the 2020-2021 influenza season.

Coronavirus Update With Anthony Fauci - October 28, 2020 Oct 30, 2020

Anthony S. Fauci, MD, returns to JAMA's Q&A series to discuss the latest developments in the COVID-19 pandemic, including the continued importance of nonpharmaceutical interventions (masking, handwashing, physical distancing) for managing rising case numbers in the US and globally. Recorded October 28, 2020.

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Preventing the Spread of SARS-CoV-2 With Masks and Other “Low-tech” Interventions

Coronavirus Vaccine Update With Paul A. Offit, MD Oct 29, 2020

Paul A. Offit, MD, of the Children's Hospital of Philadelphia, returns to JAMA's Q&A series to provide an update on progress in COVID-19 vaccine development. Recorded October 27, 2020.

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Developing a SARS-CoV-2 Vaccine at Warp Speed

October 2020 Medical News Summary Oct 27, 2020

Large Meta-analysis Digs Into Obesity’s COVID-19 Risks; As Their Numbers Grow, COVID-19 “Long Haulers” Stump Experts; Telephone Visits Surge During the Pandemic, but Will They Last?

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Preventing the Spread of SARS-CoV-2 With Masks and Other “Low-tech” Interventions

The Costs of Coronavirus Oct 22, 2020

The costs of the coronavirus pandemic are unprecedented in their dimensions: David M. Cutler, PhD, of Harvard University discusses financial costs: the $16 trillion virus.

Lisa Cooper, MD, MPH, of Johns Hopkins University discusses the costs to communities of color in excess deaths and bereavement.

Charles R. Marmar, MD, of NYU Grossman School of Medicine discusses the mental health costs. Recorded October 20, 2020.

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Coronavirus Q&A With Andy Slavitt, MBA Oct 21, 2020

Andy Slavitt, MBA, discusses recent developments in the COVID-19 pandemic and the US response. Slavitt is former Acting CMS Administrator in the Obama administration, board director at the United States of Care in Washington, DC, and a Distinguished Health Policy Fellow at the Leonard Davis Institute of Health Economics at the University of Pennsylvania in Philadelphia. Recorded October 16, 2020.

Can We Count on Herd Immunity to Control COVID-19? Oct 19, 2020

Many people are hoping that enough people develop resistance to COVID-19, either from being exposed to the disease or from vaccination, to develop herd immunity that will enable society to return to normal. But will that happen? Saad Omer, MD, from the Yale Institute for Global Health, discusses his JAMA article on herd immunity and how much we can count on having it to return society to normal from this COVID-19 pandemic.

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Herd Immunity and Implications for SARS-CoV-2 Control

Prioritizing Racial and Ethnic Minority Populations for Coronavirus Vaccination Oct 16, 2020

The National Academy of Medicine has recommended that racial minority populations receive priority for vaccination because they have been hard hit by the pandemic and are "worse off" socioeconomically. US law is inconsistent on whether race/ethnicity can be an explicit criterion for achieving equity and diversity. Lawrence O. Gostin, JD, of Georgetown University and Michelle A. Williams, ScD, of Harvard T.H. Chan School of Public Health discuss ways to achieve the public health objective of protecting vulnerable communities while adhering to law and ethics. Recorded October 14, 2020.

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Is It Lawful and Ethical to Prioritize Racial Minorities for COVID-19 Vaccines?

Digging Into Obesity’s COVID-19 Risks Oct 15, 2020

University of North Carolina (UNC) at Chapel Hill nutrition scholar Barry Popkin, PhD, and JAMA Medical News Associate Managing Editor Jennifer Abbasi discuss new findings on obesity and COVID-19. Popkin is the lead author of a systematic review and meta-analysis on the topic that was published recently in Obesity Reviews. He is a distinguished professor in the department of nutrition at the UNC Gillings School of Global Public Health.

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Sensible Medicine—Balancing Intervention and Inaction During the COVID-19 Pandemic Oct 15, 2020

Interview with Christopher W. Seymour, MD, MSc, author of Sensible Medicine—Balancing Intervention and Inaction During the COVID-19 Pandemic

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Sensible Medicine—Balancing Intervention and Inaction During the COVID-19 Pandemic

Who Gets Coronavirus Vaccine First? Oct 07, 2020

On October 2 the US National Academies of Science, Engineering, and Medicine issued its consensus Framework for Equitable Allocation of a COVID-19 Vaccine. William H. Foege, MD, MPH, emeritus distinguished professor of International Health at the Rollins School of Public Health at Emory University, cochaired the committee that authored the report and discusses its recommendations. Recorded October 2, 2020.

Coronavirus Vaccine Update From the FDA Oct 07, 2020

Peter Marks, MD, PhD, directs the US FDA's Center for Biologics Evaluation and Research (CBER) and will "call the balls and strikes" on any COVID-19 vaccine, according to FDA Commissioner Stephen Hahn. He joins JAMA Editor Howard Bauchner, MD, for an update on vaccine progress to date and prospects for pre-election political interference in the FDA approval process. Recorded October 5, 2020.

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Unwavering Regulatory Safeguards for COVID-19 Vaccines

US Adults’ Preferences for Public Allocation of a Vaccine for Coronavirus Disease 2019 Oct 06, 2020

Sarah E. Gollust, PhD joins JAMA Network Open Digital Media Editor, Seth Trueger, MD, MPH, to discuss a survey study examining public perception of high priority groups for receipt of an eventual coronavirus disease 2019 vaccine in case of shortage of supply. Read the article here: https://ja.ma/3d2101T.

JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Sweden and COVID-19 Oct 02, 2020

Sweden’s response to the COVID-19 pandemic differed from its neighbors in Europe. Lockdowns were minimized with the belief that they would be more damaging than the virus itself. Much criticism was levied at the country regarding these policies. Anders Tegnell, MD, is the head of the Department of Public Health Analysis and Data Management, Deputy Director General at the Public Health Agency of Sweden, and had been Sweden's state epidemiologist since 2013. He discusses what Sweden did in response to COVID-19 and what their outcomes were.

Coronavirus Q&A With Anthony Fauci, MD – September 25, 2020 Sep 29, 2020

Anthony S. Fauci, MD, returns to JAMA's Q&A series to discuss the latest developments in the COVID-19 pandemic. Recorded September 25, 2020.

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Reassuring the Public and Clinical Community About the Scientific Review and Approval of a COVID-19 Vaccine

Assessment of Disparities in COVID-19 Testing and Infection Across Language Groups in Seattle, Washington Sep 29, 2020

H. Nina Kim, MD, MSc and Herbert C. Duber, MD, MPH join JAMA Network Open Digital Media Editor, Seth Trueger, MD, MPH, to discuss a cross-sectional study evaluating the proportion of patients tested for coronavirus disease 2019 (COVID-19) and the proportion of positive cases, using language as a surrogate for immigrant status. Read the article here: https://ja.ma/3d2101T.

JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Coronavirus Update With Michael T. Osterholm, PhD, MPH Sep 25, 2020

Michael T. Osterholm, PhD, MPH, returns to JAMA's Coronavirus Q&A series to discuss the latest developments in the COVID-19 pandemic. He is director of the Center for Infectious Disease Research and Policy (CIDRAP) at University of Minnesota and a veteran of pandemic planning. Recorded September 23, 2020.

Related Article(s):

Fairly Prioritizing Groups for Access to COVID-19 Vaccines

COVID-19 Vaccine Approval and the FDA Sep 23, 2020

Hydroxychloroquine and convalescent plasma approvals by the FDA under Emergency Use Authorization (EUA) protocols have raised concerns the agency is under withering political pressure to fast-track a COVID-19 vaccine before it is proven safe and effective. Joshua Sharfstein, MD, Johns Hopkins Bloomberg School of Public Health, and JAMA Associate Editor Preeti Malani, MD, University of Michigan, discuss implications for public health and policy responses to ensure vaccine safety. Recorded September 18, 2020.

September 2020 Medical News Summary Sep 22, 2020

What Happens When COVID-19 Collides With Flu Season?; Flu Vaccination Urged During COVID-19 Pandemic; COVID-19 and mRNA Vaccines—First Large Test for a New Approach

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The Science of Persuasion Offers Lessons for COVID-19 Prevention Sep 16, 2020

Science communications expert Dominique Brossard, PhD, and JAMA Medical News Associate Managing Editor Jennifer Abbasi discuss research-based strategies to encourage mask wearing, social distancing, and hand washing during the COVID-19 pandemic. Dr. Brossard is a professor and chair of the Department of Life Sciences Communication at the University of Wisconsin-Madison and part of a new COVID-19-focused National Academies of Science, Engineering, and Medicine group.

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The Science of Persuasion Offers Lessons for COVID-19 Prevention

Regulatory Decision-making on COVID-19 Vaccines During a Public Health Emergency Sep 15, 2020

Interview with Aaron S. Kesselheim, MD, author of Regulatory Decision-making on COVID-19 Vaccines During a Public Health Emergency

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Regulatory Decision-making on COVID-19 Vaccines During a Public Health Emergency

Mobile Phone Location Data Indications of Travel and Stay-at-Home Mandates and COVID-19 Infection Rates in the US Sep 15, 2020

Song Gao, PhD and Ajay K. Sethi, PhD join JAMA Network Open Digital Media Editor, Seth Trueger, MD, MPH, to discuss a cross-sectional study using anonymous location data from 45 million mobile phones to determine if stay-at home orders were associated with decreased median travel distance and slower #COVID19 spread.

Read the article here: https://ja.ma/2ZCqm0A.

JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Hypertension, Obesity, and COVID-19 Sep 14, 2020

New data show unfavorable US trends in hypertension and obesity, with communities of color doing worse. National Institute of Diabetes and Digestive and Kidney Diseases Director Griffin P. Rodgers, MD, and National Heart, Lung, and Blood Institute Director Gary H. Gibbons, MD, discuss the implications for COVID-19 outcomes and public health. Recorded September 10, 2020.

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Trends in Blood Pressure Control Among US Adults With Hypertension, 1999-2000 to 2017-2018

Association of Vitamin D Status and Other Clinical Characteristics With COVID-19 Test Results Sep 08, 2020

David O. Meltzer, MD, PhD, joins JAMA Network Open Digital Media Editor, Seth Trueger, MD, MPH, to discuss a cohort study examining whether patients’ most recent vitamin D levels and treatment for insufficient vitamin D levels are associated with test results for coronavirus disease 2019 (COVID-19).

Read the article here: https://ja.ma/2ZkvGpf.

JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

SARS-CoV-2 Infection in Children and Adolescents—A Systematic Review Sep 08, 2020

JAMA Pediatrics Editors' Summary by Dimitri Christakis, MD, MPH, Editor in Chief, and Frederick Rivara, MD, MPH, Editor in Chief of JAMA Network Open for the September 8, 2020 issue.

Corticosteroids for COVID-19: New Evidence of Benefit Sep 04, 2020

A conversation with Jonathan A. C. Sterne, MA, MSc, PhD, of the University of Bristol, Todd W. Rice, MD, MSc, of Vanderbilt University, and Janet V. Diaz, MD, of the World Health Organization (WHO) on the latest research supporting the use of hydrocortisone and dexamethasone for treatment of COVID-19 ARDS. Recorded September 2, 2020.

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Effect of Hydrocortisone on 21-Day Mortality or Respiratory Support Among Critically Ill Patients With COVID-19

What Is It Like to Have COVID-19? Sep 01, 2020

COVID-19 continues to rapidly spread throughout the world. In the past few months, the population affected by the disease has shifted from older to younger patients. Public health officials are concerned that younger people seem not to be very compliant with recommendations regarding masking and social distancing. It is believed that younger people think that the adverse consequences of the disease occur in the elderly and not in them. Garret Salzman, MD, is a resident physician at UCLA and contracted the disease. He is young and healthy, but he has had substantial disability from COVID-19. He tells a cautionary tale of his experience with COVID-19 that this is not a benign disease in young people, that they need to be careful.

Coronavirus Vaccine Update Aug 26, 2020

Paul A. Offit, MD, of the Children's Hospital of Philadelphia provides an update on COVID-19 vaccine development. Recorded August 24, 2020.

Modeling Contact Tracing Strategies for COVID-19 Aug 25, 2020

Alyssa Bilinski, MS, and Joshua A. Salomon, PhD, join JAMA Network Open Digital Media Editor, Seth Trueger, MD, MPH, to discuss a mathematical modeling study examining the potential for contract tracing to reduce the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the context of reduced physical distancing under different assumptions for case detection, tracing, and quarantine efficacy. Read the article here: https://ja.ma/3ixDJ9j

JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open.

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Coronavirus Update From the CDC – August 20, 2020 Aug 24, 2020

CDC Director Robert Redfield, MD, discusses recent developments in the COVID-19 pandemic and US response, including prospects for dual outbreaks of COVID-19 and influenza in the fall and winter.

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Addressing Influenza Vaccination Disparities During the COVID-19 Pandemic

Coronavirus Update With Ezekiel J. Emanuel, MD, PhD Aug 21, 2020

Ezekiel Emanuel, MD, PhD, of the University of Pennsylvania's Perelman School of Medicine, Department of Medical Ethics and Health Policy, discusses recent developments in the COVID-19 pandemic. Recorded August 19, 2020.

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The Consequences of Not Vaccinating for Measles Aug 14, 2020

Before COVID-19, even though most children got vaccinated for measles, too many did not, resulting in worsening outbreaks of measles. People forgot how bad a disease measles is and became lax about getting their children vaccinated. Now in the COVID-19 era everyone is aware of what an out-of-control infectious disease can do and we are all anxiously awaiting a COVID-19 vaccine. Will this experience help encourage parents to get their children vaccinated? We discussed the problems of an adequate measles vaccination with Dr. Saad Omer, PhD, from the Yale Institute for Global Health at Yale University in New Haven, Connecticut.

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Vaccine Refusal and Measles Outbreaks in the US

The Intersection Between Flu and COVID-19 Aug 14, 2020

As the COVID-19 pandemic continues to spread throughout the world, flu season is almost upon us. This is concerning because there will be an overlap between flu and COVID-19 and patients could get both diseases. Daniel Solomon, MD, from the Division of Infectious Diseases at the Brigham and Women’s Hospital of the Harvard Medical School in Boston, discusses COVID-19 and how the flu might pan out this year.

How to Reopen Schools in the COVID-19 Era Aug 13, 2020

One of the most contentious issues relating to COVID-19 is when to reopen schools. This is a complicated matter because placing people in close quarters risks spread of the disease. Yet children being at home makes it difficult for their working parents to manage their affairs and can potentially affect the learning experience. JAMA Associate Editor Preeti Malani, MD, chief health officer for the University of Michigan, discusses school reopening and how the University of Michigan is addressing this problem.

Why Are We Still Talking About Hydroxychloroquine as a Treatment for COVID-19? Aug 13, 2020

The use of hydroxychloroquine as a treatment for COVID-19 serves as an example of what is wrong with medical information being widely disseminated before it is thoroughly vetted by peer review. Preliminary studies of this treatment modality were spread widely, creating false hope that a treatment for COVID-19 existed. Several randomized trials have shown that hydroxychloroquine is not an effective therapy for COVID-19.

David Juurlink, MD, PhD, from the University of Toronto summarizes the evidence base regarding hydroxychloroquine and COVID-19.

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Number of US Patients With Newly Identified Cancers Before and During the COVID-19 Pandemic Aug 11, 2020

Harvey W. Kaufman, MD joins JAMA Network Open Digital Media Editor, Seth Trueger, MD, MPH, to discuss a cross-sectional study examining changes in the number of patients with newly identified cancer before and during the coronavirus disease 2019 (COVID-19) pandemic in the United States.

Read the article here: https://ja.ma/31khw7X.

JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Coronavirus Update From the WHO Aug 07, 2020

Soumya Swaminathan, MD, DNB, chief scientist at the World Health Organization (WHO), discusses the global coronavirus pandemic and the WHO response. Recorded August 5, 2020.

Update on Dexamethasone for the Treatment of COVID-19 Aug 05, 2020

Few treatments have proven to be effective for treating COVID-19. Recently, a clinical trial reporting the results of dexamethasone for treating COVID-19 was published and has received a great deal of attention in the popular media. Greg Curfman, MD, JAMA Deputy Editor, reviews the study and discusses what the findings do or do not reveal about the efficacy of dexamethasone for treating COVID-19.

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Coronavirus Q&A With Anthony Fauci, MD – August 3, 2020 Aug 05, 2020

Anthony Fauci, MD, White House Coronavirus Task Force member and director of the National Institute of Allergy and Infectious Diseases, discusses latest developments in the COVID-19 pandemic. Recorded August 3, 2020.

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Experiences of Home Health Care Workers during COVID-19 in New York City Aug 04, 2020

Interview with Madeline R. Sterling, MD, author of Experiences of Home Health Care Workers in New York City During the Coronavirus Disease 2019 Pandemic: A Qualitative Analysis, and Theresa A. Allison, MD, PhD, author of Extreme Vulnerability of Home Care Workers During the COVID-19 Pandemic—A Call to Action

Prevalence of SARS-CoV-2 Infection Among Health Care Workers in Houston, Texas Aug 04, 2020

Roberta L. Schwartz, PhD joins JAMA Network Open Digital Media Editor, Seth Trueger, MD, MPH, to discuss a cross-sectional study examining rates of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection among asymptomatic health care workers and community residents in the greater Houston, Texas, area.

Read the article here: https://ja.ma/3f8lvcz.

JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

COVID-19 and the FDA Aug 03, 2020

US Food and Drug Administration (FDA) Commissioner Stephen Hahn, MD, discusses the agency's role in responding to the COVID-19 pandemic. Recorded July 30, 2020.

COVID-19 and School Reopenings Jul 31, 2020

Katherine Auger, MD, MSc, of Cincinnati Children's Hospital and Julie Donohue, PhD, of University of Pittsburgh's Graduate School of Public Health discuss K-12 school reopening policy options and the way forward for the 2020-21 school year. Recorded July 29, 2020.

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Association Between Statewide School Closure and COVID-19 Incidence and Mortality in the US

COVID-19 and Health Justice Jul 30, 2020

Ford Foundation President Darren Walker discusses the role of philanthropic organizations in responding to the COVID-19 pandemic and to health inequities. Recorded July 28, 2020.

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The Work of Philanthropy in Responding to COVID-19 and Addressing Inequality

Risk Factors and Mortality Among Residents With COVID-19 in Long-term Care Facilities Jul 28, 2020

David N. Fisman, MD, MPH joins JAMA Network Open Digital Media Editor, Seth Trueger, MD, MPH, to discuss a cohort study that examines the trends and risk factors associated with coronavirus disease 2019 (COVID-19) death in long-term care facilities in Ontario, Canada.

Read the article here: https://ja.ma/39oLDyy.

JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Coronavirus Update With Eric Topol, MD Jul 27, 2020

Eric Topol, MD, Scripps Research EVP and omnivorous science health care and tech commentator, discusses the evolving COVID-19 pandemic. Recorded July 23, 2020.

Completion of Advance Directives and Documented Care Preferences During the COVID-19 Pandemic Jul 21, 2020

Catherine L. Auriemma, MD joins JAMA Network Open Digital Media Editor, Seth Trueger, MD, MPH, to discuss a cohort study that examines changes in completion of and expressed preferences on an online advanced directive platform during the coronavirus 2019 (COVID-19) pandemic. Read the article here: https://ja.ma/39gbXLe.

JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Remdesivir and Dexamethasone for the Treatment of COVID-19 Jul 20, 2020

Both remdesivir and dexamethasone have been promoted as effective treatments for COVID-19. JAMA Deputy Editor Greg Curfman, MD, and Professor Rachel Sachs, JD, from the Washington University School of Law discuss the science and health policy aspects of these COVID-19 treatments.

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Missed Opportunities on Emergency Remdesivir Use

Coronavirus Update With CDC Director Robert R. Redfield, MD Jul 16, 2020

CDC Director Robert R. Redfield, MD, discusses the ongoing COVID-19 pandemic and the agency’s latest recommendations. Recorded July 14, 2020.

Related Article(s):

Universal Masking to Prevent SARS-CoV-2 Transmission—The Time Is Now

Coronavirus in Houston — Report From the Front Lines Jul 14, 2020

Kalpalatha K. Guntupalli, MD, of Baylor College of Medicine discusses the surge and ICU management of COVID-19 patients in Houston, Texas. Recorded July 10, 2020.

Related Article(s):

Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area

Characteristics of the Randomized Clinical Trials for COVID-19 Launched During the Pandemic Jul 14, 2020

Ramez Kouzy, MD, Joseph Abi Jaoude, MD, and Ethan Ludmir, MD join JAMA Network Open Digital Media Editor, Seth Trueger, MD, MPH, to discuss a systematic review examining current randomized clinical trials of therapeutic agents to treat coronavirus disease 2019 (COVID-19).

Read the article here: https://ja.ma/2B21PJs.

How Is COVID-19 Transmitted? Jul 13, 2020

Whether the SARS-CoV-2 virus is transmitted by droplets or aerosol influences which public health interventions might slow its spread. Michael Klompas, MD, professor of medicine at Harvard Medical School, explains evidence to date about mechanisms of coronavirus transmission and implications for pandemic containment and mitigation efforts.

Coronavirus Update – July 2020 Jul 10, 2020

Infectious disease physician Rochelle P. Walensky, MD, of Harvard University discusses the ongoing COVID-19 pandemic. Recorded July 8, 2020.

Coronavirus Q&A With Anthony Fauci, MD – July 2, 2020 Jul 03, 2020

Anthony Fauci, MD, White House Coronavirus Task Force member and Director of the National Institutes of Allergy and Infectious Diseases, discusses latest developments in the COVID-19 pandemic. Recorded on July 2, 2020.

Estimation of Excess Deaths From COVID-19 in the United States, March to May 2020 Jul 01, 2020

Interview with Daniel M. Weinberger, PhD, author of Estimation of Excess Deaths Associated With the COVID-19 Pandemic in the United States, March to May 2020

Update From the CDC With Anne Schuchat, MD Jul 01, 2020

Anne Schuchat, MD, Principal Deputy Director of the Centers for Disease Control and Prevention (CDC), discusses latest developments in the COVID-19 pandemic. Recorded on June 29, 2020.

Related Article(s):

Interpreting Diagnostic Tests for SARS-CoV-2

Coronavirus in Brazil: Report From the Front Lines Jun 30, 2020

Intensivists Flavia R. Machado, MD, PhD, of the Federal University of São Paulo, and Jorge Salluh, MD, PhD, of the D’OR Institute for Research and Education in Rio de Janeiro, discuss the surge of COVID-19 cases and ICU management of patients in Brazil. Recorded June 26, 2020.

Related Article(s):

Latin America and Its Global Partners Toil to Procure Medical Supplies as COVID-19 Pushes the Region to Its Limit

Simulation of Pool Testing Strategies to Identify Patients With COVID-19 Jun 30, 2020

Alhaji Cherif, PhD and Peter Kotanko, MD join JAMA Network Open Editors to discuss a study examining the feasibility of using pool testing to identify patients with coronavirus disease 2019 (COVID-19) in a setting with limited testing availability.

Read the article here: https://ja.ma/3e8OCvJ

JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Taking a Closer Look at COVID-19, Health Inequities, and Racism Jun 29, 2020

Chicago public health legend and retired physician Linda Rae Murray, MD, discusses systemic racism and the pandemic’s disproportionate effect among African Americans and other people of color with JAMA Medical News Associate Managing Editor Jennifer Abbasi. Dr Murray is an adjunct assistant professor at the University of Illinois at Chicago School of Public Health and a past president of the American Public Health Association.

The Next COVID-19 Phase Jun 26, 2020

Michael Osterholm, PhD, MPH, of UMN's Center for Infectious Disease Research and Policy, discusses the summer rise in US COVID-19 cases, prospects for school reopening, a "second wave" in the fall, and more. Recorded June 24, 2020.

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Vulnerability to Pandemic Flu Could Be Greater Today Than a Century Ago

Variation in Ventilator Allocation Guidelines by US State During the COVID-19 Pandemic Jun 23, 2020

Gina M. Piscitello, MD joins JAMA Network Open Editors to discuss a systematic review that examines US state guidelines for ventilator allocation decision-making during the coronavirus disease 2019 pandemic. Read the article here: https://ja.ma/2YpfVxf.

JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Prevalence of Taste and Smell Dysfunction in Coronavirus Disease 2019 Jun 18, 2020

Interview with Fabio Ferreli, MD, and Giuseppe Mercante, MD, authors of Prevalence of Taste and Smell Dysfunction in Coronavirus Disease 2019

Coronavirus Q&A: Clinical Update With Carlos del Rio, MD Jun 17, 2020

Infectious disease and global health expert Carlos del Rio, MD, of Emory University provides an update on the status of the #COVID19 pandemic in summer 2020, prospects for effective treatment and prevention, communicating the ongoing risk to the public, and more. Recorded June 15, 2020.

COVID-19 Q&A: Critical Care Update Jun 10, 2020

COVID-19 critical care update with Maurizio Cecconi, MD, of Humanitas University in Milan, Italy, and JAMA Associate Editor Derek C. Angus, MD, MPH, of the University of Pittsburgh. Recorded June 8, 2020.

COVID-19 Outbreak and Enrollment in Cancer Clinical Trials Jun 09, 2020

Joseph M. Unger, PhD joins JAMA Network Open Editors to discuss a cohort study investigating how the coronavirus disease 2019 (COVID-19) pandemic is associated with national enrollment in cancer clinical trials.

Read the article here: https://ja.ma/2MNv1Gs.

JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Telepsychiatry and the Coronavirus Disease 2019 Pandemic—Outcomes of Rapid Virtualization of Psychiatric Care Jun 08, 2020

Interview with Jay Shore, MD, MPH, author of Telepsychiatry and the Coronavirus Disease 2019 Pandemic—Current and Future Outcomes of the Rapid Virtualization of Psychiatric Care

Coronavirus Q&A: Opening School in the Fall Jun 05, 2020

Joshua M. Sharfstein, MD, and Christopher Morphew, PhD, of Johns Hopkins University discuss options for opening primary, middle, and high schools in fall 2020. Recorded June 3, 2020.

Coronavirus Q&A With Anthony Fauci, MD Jun 04, 2020

NIAID Director Anthony Fauci, MD, discusses recent developments in the global COVID-19 pandemic with JAMA Editor in Chief Howard Bauchner, MD. Recorded June 2, 2020.

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Anthony Fauci, MD, on COVID-19 Vaccines, Larry Kramer, and Dealing With Criticism

Coronavirus Vaccine Development Jun 03, 2020

Paul Offit, MD, of the Children's Hospital of Philadelphia, discusses principles and progress to date in COVID-19 vaccine development. Recorded June 1, 2020.

Venous Thrombosis Among Critically Ill Patients With COVID-19 Jun 02, 2020

Tristan Morichau-Beauchant, MD joins JAMA Network Open Editors to discuss a case series that reports a systematic assessment of deep vein thrombosis among patients in an intensive care unit in France with severe coronavirus disease 2019 (COVID-19). Read the article here: https://ja.ma/307784k.

JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Coronavirus Q&A: Managing the Pandemic Jun 01, 2020

Paul Starr, PhD, Professor of Sociology and Public Affairs at Princeton University, discusses policy options for achieving a new normal in the COVID-19 pandemic. Recorded Thursday, May 28, 2020.

The NIH Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV) Initiative May 21, 2020

US National Institutes of Health (NIH) Director Francis S. Collins, MD, PhD, discusses the agency's new initiative to collaborate with other agencies and industry to accelerate development and testing of COVID-19 treatments and vaccines. Recorded May 19, 2020.

Prioritizing Physician Mental Health as COVID-19 Marches On May 20, 2020

The University of New Mexico's Eileen Barrett, MD, MPH, speaks with JAMA's Jennifer Abbasi about the pandemic's mental and emotional toll on health care workers—and how they and their employers can safeguard their well-being.

Read the article: Prioritizing Physician Mental Health as COVID-19 Marches On

Estimated Rates of COVID-19 in Border Counties in Iowa vs Illinois May 19, 2020

Was the stay-at-home order in Illinois associated with different rates of coronavirus disease 2019 (COVID-19) compared with Iowa, which did not issue a stay-at-home order? Wei Lyu, MS and George L. Wehby, PhD join JAMA Network Open Editors to discuss a cross-sectional study comparing coronavirus disease 2019 (COVID-19) cases in border counties in Iowa and Illinois to find out if issuing a stay-at-home order helped limit the spread of COVID-19 cases. Read the article here: https://ja.ma/2LNprmO.

JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Immunity Passports in the Time of COVID-19 May 13, 2020

Ezekiel Emanuel, MD, PhD, of the Perelman School of Medicine's Department of Medical Ethics and Health Policy, discusses the use of immunity licensing (immunity passports) as a means to restore public travel, activity, and the economy following the first wave of the COVID-19 pandemic. Recorded May 11, 2020.

Demand for US Hospital Inpatient and Intensive Care Unit Beds for Patients With COVID-19 May 12, 2020

Ruoran Li, MPhil joins JAMA Network editors to discuss a comparative effectiveness study describing and comparing the intensive care unit and inpatient bed needs for patients with coronavirus disease 2019 (COVID-19) in 2 cities in China to estimate the peak number of intensive care unit beds needed in US cities if an outbreak equivalent to that in Wuhan occurs. Read the article here: https://ja.ma/3cySE0m.

JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Preprints & Twitter in the Time of COVID-19 May 11, 2020

Preprint servers and professional discourse on social media sites like Twitter have been incredibly helpful in spreading useful information as the COVID-19 pandemic changes over time. But they clearly function as a double-edged sword, spreading information rapidly prior to traditional peer review. JAMA Network Open Editors Eli Perencevich, MD, MS and Roy Perlis, MD, MSc join us to discuss on JNOLive.

JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

COVID-19 and Health Care's New Normal May 06, 2020

Don Berwick, MD, MPP, of the Institute for Healthcare Improvement, discusses choices societies and the medical profession can make to improve health care and reduce inequities as we move out of the acute phase of the coronavirus pandemic.

Coronavirus Q&A: Update From the CDC May 05, 2020

Anne Schuchat, MD, Principal Deputy Director of the Centers for Disease Control and Prevention (CDC), discusses evolution of CDC guidance and latest developments in the COVID-19 pandemic. Recorded Friday May 1, 2020.

Contact Tracing Assessment of COVID-19 Transmission Dynamics in Taiwan May 01, 2020

Interview with Hsien-Ho Lin, MD, ScD, author of Contact Tracing Assessment of COVID-19 Transmission Dynamics in Taiwan and Risk at Different Exposure Periods Before and After Symptom Onset

COVID-19 and US Health Care Spending Apr 29, 2020

The US spends more on health care as a proportion of its GDP than any other nation. Will the COVID-19 pandemic reduce or accelerate that spending? Sherry Glied, PhD, Dean and Professor of Public Service at New York University, explains. Recorded Monday, April 27, 2020.

Read the article

The Potential Effects of Coronavirus on National Health Expenditures

Caution Needed on the Use of Chloroquine and Hydroxychloroquine for Coronavirus Disease 2019 Apr 28, 2020

Steven M. Bradley, MD, MPH joins JAMA Network editors to discuss a randomized clinical trial evaluating the safety and efficacy of 2 chloroquine diphosphate dosages in patients with severe coronavirus disease 2019 (COVID-19). Read the editorial here: https://ja.ma/2JC5sGx.

JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Pandemic Part 2: A Trip to Philadelphia’s Mutter Museum Apr 27, 2020

A new exhibit on the 1918 flu pandemic asks: What is an individual's responsibility to their community during a pandemic? Exhibit curator Jane Boyd and museum manager Nancy Hill take Jennifer Abbasi on a tour of the medical museum's new exhibit just weeks before the COVID-19 outbreak first emerged.

Pandemic Part 1: 1918 Flu Pandemic and COVID-19

Read the article:

Twentieth-Century Lessons for a Modern Coronavirus Pandemic

Pandemic Part 1: 1918 Flu Pandemic and COVID-19 Apr 27, 2020

Medical historian Howard Markel, MD, PhD, director of the University of Michigan's Center for the History of Medicine, speaks with JAMA Fishbein fellow Angel Desai, MD, about lessons from the devastating 1918 flu pandemic. Markel discusses his research into the effects of social distancing on US death rates during the worldwide outbreak.

Pandemic Part 2: A Trip to Philadelphia’s Mutter Museum

Read the article:

Twentieth-Century Lessons for a Modern Coronavirus Pandemic

Coronavirus (COVID-19) Update: Ventilatory Management for COVID-Related Respiratory Failure Apr 24, 2020

Management of COVID-19-related respiratory failure differs from what is necessary for ARDS. Rather than having alveolar edema, COVID-19 patients have pulmonary vascular dysregulation. Gas exchange is severely compromised with little reduction in lung compliance. Ventilatory support for COVID-19 patients requires higher than normal tidal volumes with minimal PEEP and allowance for higher than usual serum CO2 levels. How the unique pathophysiology of respiratory failure should be treated is discussed by John J. Marini, MD, professor of medicine at the University of Minnesota.

Predicting the COVID-19 Pandemic Apr 24, 2020

Marc Lipsitch, DPhil, an infectious diseases epidemiologist developing biological and modeling approaches to pathogen transmission and outbreaks, discusses evolution of the COVID-19 pandemic in summer and fall 2020. Originally recorded April 22, 2020.

Coronavirus and Health Policy Apr 22, 2020

JAMA Health Forum editors John Ayanian, MD, MPP, and Melinda Buntin, PhD, discuss changes in US health care and health policy driven by the coronavirus pandemic. Recorded April 16, 2020.

COVID-19: From Mitigation to Containment Apr 22, 2020

Rochelle Walensky, MD, MPH, of Harvard University discusses public health strategies and policies for lifting shelter-in-place and quarantine and for returning the US to a new post-first-wave normal. Recorded Monday April 20, 2020.

New York City Coronavirus (COVID-19) Update Apr 15, 2020

New York City coronavirus update from Mitchell Katz, MD, President and CEO of NYC Health + Hospitals, the largest municipal public health system in the United States. Recorded April 13, 2020.

Coronavirus (COVID-19) Update: Clinical Review Apr 10, 2020

Questions about testing, chloroquine toxicity, duration of immunity and reinfection, and what to expect next are gripping the US as the novel coronavirus spreads. JAMA Associate Editor Preeti Malani, MD, professor of medicine and Chief Health Officer at the University of Michigan, discusses recent developments in a live conversation with JAMA Editor in Chief Howard Bauchner. Recorded on April 6, 2020.

Q&A With Anthony Fauci, MD Apr 10, 2020

NIAID Director and Presidential Coronavirus Task Force Advisor Anthony Fauci, MD, discusses recent developments in the global COVID-19 pandemic with JAMA Editor Howard Bauchner, MD. Recorded April 8, 2020.

Coronavirus Q&A: Former Utah Governor and HHS Secretary Mike Leavitt Apr 10, 2020

US states are taking the lead in managing the COVID-19 pandemic. What can state governors expect from the federal government and from the US Department of Health and Human Services? Governor Mike Leavitt from Leavitt Partners joins JAMA Editor Howard Bauchner, MD, in this live Q&A. Recorded April 8, 2020.

Coronavirus (COVID-19) Update: Reusing Face Masks and N95 Respirators Apr 08, 2020

Shortages of face masks and N95 respirators have forced clinicians and hospitals to reuse these normally disposable items. Ron Shaffer, PhD, former CDC PPE Research Branch Chief, discusses effective sterilization techniques and how to test that the equipment stays protective after sterilization.

Coronavirus Disease 2019 (COVID-19) Update: Epidemics in History Apr 06, 2020

Infectious epidemics have always driven change and triggered discrimination in human societies. Frank Snowden, DPhil, Professor Emeritus of History and History of Medicine at Yale University and author of Epidemics and Society: From the Black Death to the Present (Yale University Press, 2019), puts the COVID-19 pandemic in historical context.

Coronavirus (COVID-19) Update: Safe Shopping at Stores and Pharmacies Apr 03, 2020

Food and medicine shopping is essential during the COVID-19 pandemic, but requires getting out and standing close to strangers at a time when social distancing and sheltering-in-place are recommended to slow spread of disease. David Aronoff, MD, director of the Division of Infectious Diseases at Vanderbilt University in Nashville, explains how to minimize COVID-19 risk while shopping.

Coronavirus (COVID-19) Update: Critical Care Management Apr 02, 2020

Noninvasive ventilation (NIV), working with dying patients’ families, use of experimental therapies, and more. JAMA Associate Editor Derek Angus, MD, MPH, Distinguished Professor and Chair of Critical Care Medicine at the University of Pittsburgh, provides a COVID-19 ICU management update.

Watch the recording of this livestream

Coronavirus (COVID-19) Update: The Near Future Apr 01, 2020

How does the current pandemic compare to historical infectious outbreaks and what can we expect in summer and fall of 2020? Nicholas Christakis, MD, PhD, MPH, director of the Human Nature Lab, Co-director of the Institute of Network Science, and Sterling Professor of Social and Natural Science at Yale University, discusses the epidemiology of COVID-19.

Humans, Viruses, and the Eye—An Early Report From the COVID-19 Front Line Mar 31, 2020

Interview with Alfred Sommer, MD, author of Humans, Viruses, and the Eye—An Early Report From the COVID-19 Front Line

Safety Recommendations for Evaluation and Surgery of the Head and Neck During the COVID-19 Pandemic Mar 31, 2020

Interview with Joshua K Tay, author of Surgical Considerations for Tracheostomy During the COVID-19 Pandemic: Lessons Learned From the Severe Acute Respiratory Syndrome Outbreak, and Babak Givi, MD, author of Safety Recommendations for Evaluation and Surgery of the Head and Neck During the COVID-19 Pandemic

Coronavirus (COVID-19) Update: Fairly Rationing ICU Care Mar 30, 2020

Hospitals need ways to make rational, fair decisions about who gets ICU beds and ventilators if COVID-19 patients overwhelm capacity. Douglas B. White, MD, MAS, Director of the Program on Ethics and Decision Making in Critical Illness at the University of Pittsburgh, discusses a framework for those decisions and a guideline he helped develop for allocation of scarce resources in public health emergencies.

Association of Coronavirus Disease 2019 (COVID-19) With Myocardial Injury and Mortality Mar 27, 2020

Interview with Robert O. Bonow, MD, Patrick T. O'Gara, MD, Clyde W. Yancy, MD, and Gregg C. Fonarow, MD, authors of Association of Coronavirus Disease 2019 (COVID-19) With Myocardial Injury and Mortality and Ajay J. Kirtane, MD

Coronavirus Disease 2019 (COVID-19) Update: PCR Testing and Shortages Mar 27, 2020

The lack of availability of COVID-19 testing has interfered with the ability to contain the spread of disease. Omai Garner, PhD, laboratory director for Clinical Microbiology in the UCLA health system, explains how PCR testing for COVID-19 works and why testing is in short supply.

Coronavirus (COVID-19) Update: Vaccines and Immunity Mar 26, 2020

As COVID-19 spreads globally, populations who survive their illness will become immune. Mayo Vaccine Research Group Director Gregory Poland, MD, discusses antibody responses, duration of immunity, vaccine safety, and the prospects for using convalescent serum to passively immunize people unexposed to SARS-CoV-2.

Coronavirus Disease 2019 (COVID-19) Update: How the VA Is Preparing Mar 25, 2020

As COVID-19 spreads, clinicians and health systems are struggling to prepare for a surge of patients. Richard Stone, MD, the US Veterans Health Administration's Executive in Charge, spoke with JAMA about how the VA health system is preparing for this public health emergency.

Coronavirus (COVID-19) Update: Lessons Learned From The 2003 SARS Outbreak Mar 25, 2020

In 2003, Toronto was the North American center for Severe Acute Respiratory Syndrome (SARS). The disease spread through the city’s hospitals before anyone knew what was happening. Dr Allison McGeer was a clinician caring for SARS patients and ultimately was infected herself. She describes her experience as a patient and provider and reviews lessons learned that might help others manage their regional COVID-19 outbreaks.

Coronavirus in New York - Report From the Front Lines Mar 24, 2020

The ARDS in COVID-19 patients appears more responsive to PEEP and prone ventilation, but seems to require prolonged ventilation and may be associated with myocardial injury. Michelle N. Gong, MD, MS, Chief of Critical Care Medicine at Montefiore Medical Center in the Bronx, discusses her department's experience managing critically ill coronavirus patients, procuring diagnostic tests and personal protective equipment (PPE) for her staff, and more.

Coronavirus (COVID-19) Update: Chloroquine/Hydroxychloroquine and Azithromycin Mar 24, 2020

Chloroquine was shown in 2004 to be active in vitro against SARS coronavirus but is of unproven efficacy and safety in patients infected with SARS-CoV-2. The drug's potential benefits and risks for COVID-19 patients, without and with azithromycin, is discussed by Dr. David Juurlink, head of the Division of Clinical Pharmacology and Toxicology at Sunnybrook Health Sciences Centre in Toronto.

Coronavirus Disease 2019 (COVID-19) Mitigation: Preparing Hospitals and Health Systems Mar 20, 2020

The strategy for managing the COVID-19 pandemic has shifted from containment to mitigation. What does that mean for US hospitals and health systems? Kaiser Permanente Executive Vice President Stephen M. Parodi, MD, discusses telemedicine, protecting health care workers, equipment allocation planning, and more.

Practical Aspects of Otolaryngologic Clinical Services During the COVID-19 Epidemic Mar 20, 2020

Interview with Jason Ying Kuen Chan, MBBS, author of Practical Aspects of Otolaryngologic Clinical Services During the 2019 Novel Coronavirus Epidemic: An Experience in Hong Kong

Coronavirus (COVID-19) Update: Early Safety Signals Around Ibuprofen and Renin-Angiotensin Inhibitors Mar 20, 2020

Emerging information about how SARS-CoV-2 virus infects cells has led to speculation that NSAIDs and ACE inhibitors/angiotensin receptor blockers (ARBs) may worsen clinical disease. Infectious disease physician Carlos del Rio, MD, of Emory University explains the concerns and their clinical implications.

COVID-19 Update with NIAID’s Anthony Fauci, MD; March 18, 2020 Mar 19, 2020

Diagnostic testing, NSAIDs, ACE Inhibitors, antivirals, and more. Anthony Fauci, MD from NIAID discusses latest developments in the spread and clinical management of COVID-19 and the SARS-CoV-2 virus with JAMA Editor Howard Bauchner, MD.

JAMA Coronavirus Resource Center

Coronavirus Testing – March 16 Q&A with the CDC’s Jay Butler, MD Mar 17, 2020

Coronavirus testing will help countries manage coronavirus disease 2019 (COVID-19) but will raise questions about how to counsel patients about their test results. The CDC's Deputy Director for Infectious Diseases Jay C. Butler, MD, talks with JAMA Editor Howard Bauchner about what to advise healthy patients with positive PCR results, sick patients with negative test results, exposed health care workers, and more.

COVID-19 in Seattle: Clinical Features and Managing the Outbreak Mar 16, 2020

Seattle has been a focal point for the US in the coronavirus pandemic. Doug Paauw, MD, professor of medicine at the University of Washington, in Seattle, describes the UW primary care clinic experience as this pandemic evolved. Major lessons learned included accommodating for significant numbers of staff not available to work in the clinic because of school closures, change in workflow because of shortages of personal protective equipment, physicians having to accommodate very large numbers of patient queries via telephone, email, or electronic health record, and the importance of the rapid development of local ability to test for SARS-CoV-2 independent of public health agencies.

The Effect of the COVID-19 Pandemic on Clinic Operations Mar 13, 2020

Seattle has been a focal point for the US in the coronavirus pandemic. Doug Paauw, MD, professor of medicine at the University of Washington, in Seattle, describes the UW primary care clinic experience as this pandemic evolved. Major lessons learned included accommodating for significant numbers of staff not available to work in the clinic because of school closures, change in workflow because of shortages of personal protective equipment, physicians having to accommodate very large numbers of patient queries via telephone, email, or electronic health record, and the importance of the rapid development of local ability to test for SARS-CoV-2 independent of public health agencies.

Coronavirus in Italy—Report From the Front Lines Mar 13, 2020

Physicians in Lombardy, Italy, have been overwhelmed by COVID-19 patients requiring critical care. Based on an existing ECMO center network they developed an ICU network to rapidly identify, triage, and manage patients infected with SARS-2-CoV. Maurizio Cecconi, MD, of Humanitas University in Milan discusses the region’s approach to the surge, including clinical and supply management, health care worker training and protection, and ventilation strategies, with JAMA Editor Howard Bauchner.

Read the article:

Critical Care Utilization for the COVID-19 Outbreak in Lombardy, Italy: Early Experience and Forecast During an Emergency Response

COVID-19 Update With NIAID's Anthony Fauci, MD; March 6, 2020 Mar 07, 2020

Coronavirus testing, mortality, vaccine development, containment vs mitigation, and more. JAMA Editor Howard Bauchner, MD, interviews US NIAID Director Anthony Fauci, MD, about the latest developments in SARS-CoV-2 science and global spread of infection.

JAMA Coronavirus Resource Page

COVID-19 Update From China Feb 14, 2020

By mid-February 2020 there were 60,000 confirmed cases of COVID-19, the vast majority diagnosed in Hubei Province (including Wuhan city) in mainland China. China CDC Chief Epidemiologist Zunyou Wu, MD, PhD discusses the latest COVID-19 developments in the country with JAMA Editor in Chief Howard Bauchner, MD.

The 2019 Novel Coronavirus Outbreak – Update From NIAID’s Anthony Fauci, MD Feb 07, 2020

In February 2020 the nature of the 2019-nCoV outbreak is still slowly coming into focus but it appears to be acting more like bad pandemic influenza (efficient spread, overall lower mortality) than like SARS (less efficient spread, overall higher mortality). Anthony Fauci, MD, of the US National Institute of Allergy and Infectious Diseases (NIAID) discusses the latest developments with JAMA Editor in Chief Howard Bauchner.

Coronavirus Resource Center

Coronavirus and Beyond: Responding to Biological Threats Feb 03, 2020

The 2019 novel coronavirus (2019-nCoV) outbreak exemplifies ongoing biothreats to global security, as each new threat tests principles of preparation and response at national, regional, and clinical levels. Tom Inglesby, MD, director of the Center for Health Security at the Johns Hopkins Bloomberg School of Public Health, discusses biosecurity with Angel Desai, MD, JAMA Fishbein fellow.

Coronavirus Infections—More Than Just the Common Cold Jan 28, 2020

Interview with Anthony S. Fauci, MD, author of Coronavirus Infections—More Than Just the Common Cold

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