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    Health & Fitness

    CorConsult Rx: Evidence-Based Medicine and Pharmacy

    Evidence-based medicine and drug updates for pharmacists, physicians, NPs, PA-Cs, and students that are on the go.

    Advertise

    Copyright: © All rights reserved

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    Latest Episodes:
    Bempedoic Acid and the CLEAR Outcomes Trial Mar 14, 2023
    Show notes

    On this episode, we review the recently published CLEAR-outcomes trial that was looking at bempedoic acid's (Nexletol) ability to lower the risk of CV events in patients who were unable to tolerate statins at their recommended doses.

    While recording this episode, we used the trial summary written by Dr. Alex Poppen, PharmD who is the author/owner of the book High-Powered Medicine: Landmark Clinical Trial Reviews. To see all of the study summaries that he has available, check out his website below:

    https://highpoweredmedicine.com/

    Thanks for listening!

    We want to give a big thanks to our main sponsor Pyrls. Try out their drug information app today. Visit the website below for a free trial:

    www.pyrls.com/corconsultrx

    If you want to support the podcast, check out our Patreon account. Subscribers will have access to all previous and new pharmacotherapy lectures as well as downloadable PowerPoint slides for each lecture. You can find our account at the website below:

    www.patreon.com/corconsultrx

    If you have any questions for Cole or me, reach out to us on any of the following:

    Text - 415-943-6116

    • Mike - mcorvino@corconsultrx.com
    • Cole - cswanson@corconsultrx.com
    • AJ - aalford@corconsultrx.com

    Instagram and other social media platforms - @corconsultrx

    This podcast reviews current evidence-based medicine and pharmacy treatment options. This podcast is intended to be used for educational purposes only and is intended for healthcare professionals and students. This podcast is not for patients and not intended as advice or treatment.


    Treatment and Management of Anemia *ACPE-Accredited* Mar 06, 2023
    Show notes

    On this episode, we review the treatment and management of various types of anemia. We discuss iron-deficiency anemia, B-12 and folate dificiency anemia, anemia due to CKD, anemia due to chronic disease (inflammation), and aplastic anemia.

    Cole and I are happy to share that our listeners can claim ACPE-accredited continuing education for listening to this podcast episode! We have continued to partner with freeCE.com to provide listeners with the opportunity to claim 1-hour of continuing education credit for select episodes. For existing Unlimited (Gold) freeCE members, this CE option is included in your membership benefits at no additional cost! A password, which will be given at some point during this episode, is required to access the post-activity test. To earn credit for this episode, visit the following link below to go to freeCE's website:

    https://www.freece.com/

    If you're not currently a freeCE member, we definitely suggest you explore all the benefits of their Unlimited Membership on their website and earn CE for listening to this podcast.

    Thanks for listening!

    We want to give a big thanks to our main sponsor Pyrls. Try out their drug information app today. Visit the website below for a free trial:

    www.pyrls.com/corconsultrx

    If you want to support the podcast, check out our Patreon account. Subscribers will have access to all previous and new pharmacotherapy lectures as well as downloadable PowerPoint slides for each lecture. You can find our account at the website below:

    www.patreon.com/corconsultrx

    If you have any questions for Cole or me, reach out to us on any of the following:

    Text - 415-943-6116

    • Mike - mcorvino@corconsultrx.com
    • Cole - cswanson@corconsultrx.com
    • AJ - aalford@corconsultrx.com

    Instagram and other social media platforms - @corconsultrx

    This podcast reviews current evidence-based medicine and pharmacy treatment options. This podcast is intended to be used for educational purposes only and is intended for healthcare professionals and students. This podcast is not for patients and not intended as advice or treatment.


    ACP BP Goals, Ozempic Face, and Healthy Potatoes Feb 28, 2023
    Show notes

    On this episode we cover three different topics that have been in the medical news lately. First, we compare/contrast the blood pressure goals that were published by the American College of Physicians with other prominent hypertension guidelines. Second, we discuss the semaglutide "side effect" that has been coined Ozempic Face. Finally, Cole reviews some literature surrounding the health benefits of potatoes.

    Thanks for listening!

    We want to give a big thanks to our main sponsor Pyrls. Try out their drug information app today. Visit the website below for a free trial:

    www.pyrls.com/corconsultrx

    If you want to support the podcast, check out our Patreon account. Subscribers will have access to all previous and new pharmacotherapy lectures as well as downloadable PowerPoint slides for each lecture. You can find our account at the website below:

    www.patreon.com/corconsultrx

    If you have any questions for Cole or me, reach out to us on any of the following:

    Text - 415-943-6116

    • Mike - mcorvino@corconsultrx.com
    • Cole - cswanson@corconsultrx.com
    • AJ - aalford@corconsultrx.com

    Instagram and other social media platforms - @corconsultrx

    This podcast reviews current evidence-based medicine and pharmacy treatment options. This podcast is intended to be used for educational purposes only and is intended for healthcare professionals and students. This podcast is not for patients and not intended as advice or treatment.


    A Review of Antipsychotics *ACPE-Accredited* Feb 20, 2023
    Show notes

    On this episode we review typical (first generation) and atypical (second generation) antipsychotics. We discuss receptor signaling, various adverse effects, and specific clinical pearls for the individual medications in the antipsychotic class.

    Cole and I are happy to share that our listeners can claim ACPE-accredited continuing education for listening to this podcast episode! We have continued to partner with freeCE.com to provide listeners with the opportunity to claim 1-hour of continuing education credit for select episodes. For existing Unlimited (Gold) freeCE members, this CE option is included in your membership benefits at no additional cost! A password, which will be given at some point during this episode, is required to access the post-activity test. To earn credit for this episode, visit the following link below to go to freeCE's website:

    https://www.freece.com/

    If you're not currently a freeCE member, we definitely suggest you explore all the benefits of their Unlimited Membership on their website and earn CE for listening to this podcast.

    Thanks for listening!

    We want to give a big thanks to our main sponsor Pyrls. Try out their drug information app today. Visit the website below for a free trial:

    www.pyrls.com/corconsultrx

    If you want to support the podcast, check out our Patreon account. Subscribers will have access to all previous and new pharmacotherapy lectures as well as downloadable PowerPoint slides for each lecture. You can find our account at the website below:

    www.patreon.com/corconsultrx

    If you have any questions for Cole or me, reach out to us on any of the following:

    Text - 415-943-6116

    • Mike - mcorvino@corconsultrx.com
    • Cole - cswanson@corconsultrx.com
    • AJ - aalford@corconsultrx.com

    Instagram and other social media platforms - @corconsultrx

    This podcast reviews current evidence-based medicine and pharmacy treatment options. This podcast is intended to be used for educational purposes only and is intended for healthcare professionals and students. This podcast is not for patients and not intended as advice or treatment.


    Does Morning or Bedtime Dosing of Antihypertensives Matter? *ACPE-Accredited* Feb 06, 2023
    Show notes

    On this episode, we discuss dosing antihypertensives at bedtime compared to the morning and if it impacts patient outcomes. We review the MAPEC, Hygia, and TIME studies as well as other editorials on this debated topic.

    Cole and I are happy to share that our listeners can claim ACPE-accredited continuing education for listening to this podcast episode! We have continued to partner with freeCE.com to provide listeners with the opportunity to claim 1-hour of continuing education credit for select episodes. A password, which will be given at some point during this episode, is required to access the post-activity test. To earn credit for this episode, visit the following link below to go to freeCE's website:

    www.freece.com

    For existing Unlimited freeCE members, this CE option is included in your membership benefits at no additional cost! Members can simply follow the link above to take the post-test and evaluation for this activity. If you're not currently a freeCE member, we definitely suggest you explore all the benefits of their Unlimited Membership on their website and earn CE for listening to this podcast.

    Thanks for listening!

    We want to give a big thanks to our main sponsor Pyrls. Try out their drug information app today. Visit the website below for a free trial:

    www.pyrls.com/corconsultrx

    If you want to support the podcast, check out our Patreon account. Subscribers will have access to all previous and new pharmacotherapy lectures as well as downloadable PowerPoint slides for each lecture. You can find our account at the website below:

    www.patreon.com/corconsultrx

    If you have any questions for Cole or me, reach out to us on any of the following:

    Text - 415-943-6116

    • Mike - mcorvino@corconsultrx.com
    • Cole - cswanson@corconsultrx.com
    • AJ - aalford@corconsultrx.com

    Instagram and other social media platforms - @corconsultrx

    This podcast reviews current evidence-based medicine and pharmacy treatment options. This podcast is intended to be used for educational purposes only and is intended for healthcare professionals and students. This podcast is not for patients and not intended as advice or treatment.


    New Year New Drugs: Leqembi, Airsupra, and Brenzavvy Jan 31, 2023
    Show notes

    On this episode we discuss the new drugs that have been approved in 2023 so far. We review Leqembi (lecanemab-irmb) injection for Alzheimer's disease, Airsupra (albuterol and budesonide) inhalation for as-needed use in asthma, and Brenzavvy (bexagliflozin) for type 2 diabetes. We also mention Rykindo (risperidone) ER injection, but we didn't go into much detail since we've gone over risperidone in previous episodes.

    Thanks for listening!

    We want to give a big thanks to our main sponsor Pyrls. Try out their drug information app today. Visit the website below for a free trial:

    www.pyrls.com/corconsultrx

    If you want to support the podcast, check out our Patreon account. Subscribers will have access to all previous and new pharmacotherapy lectures as well as downloadable PowerPoint slides for each lecture. You can find our account at the website below:

    www.patreon.com/corconsultrx

    If you have any questions for Cole or me, reach out to us on any of the following:

    Text - 415-943-6116

    • Mike - mcorvino@corconsultrx.com
    • Cole - cswanson@corconsultrx.com
    • AJ - aalford@corconsultrx.com

    Instagram and other social media platforms - @corconsultrx

    This podcast reviews current evidence-based medicine and pharmacy treatment options. This podcast is intended to be used for educational purposes only and is intended for healthcare professionals and students. This podcast is not for patients and not intended as advice or treatment.


    Obsessive Compulsive Disorder *ACPE-Accredited* Jan 23, 2023
    Show notes

    On this episode, we discuss the pharmacotherapy options for managing obsessive compulsive disorder (OCD). We based our discussion on the treatment algorithm created by Dr David Osser. All of Dr. Osser's work with the Psychopharmacology Algorithms Project at the Harvard South Shore Psychiatry Residency Training Program can be found at the following website:

    https://psychopharm.mobi/algo_live/#

    Cole and I are happy to share that our listeners can claim ACPE-accredited continuing education for listening to this podcast episode! We have continued to partner with freeCE.com to provide listeners with the opportunity to claim 1-hour of continuing education credit for select episodes. To earn credit for this episode, visit the following link below to reach the post-activity test for this episode:

    List of podcasts on freeCE.com

    For existing Unlimited freeCE members, this CE option is included in your membership benefits at no additional cost! Members can simply follow the link above to take the post-test and evaluation for this activity. Use the password OCD23 (all caps) to unlock the post-test for this episode.

    If you're not currently a freeCE member, we definitely suggest you explore all the benefits of their Unlimited Membership on their website and earn CE for listening to this podcast.

    Thanks for listening!

    We want to give a big thanks to our main sponsor Pyrls. Try out their drug information app today. Visit the website below for a free trial:

    www.pyrls.com/corconsultrx

    If you want to support the podcast, check out our Patreon account. Subscribers will have access to all previous and new pharmacotherapy lectures as well as downloadable PowerPoint slides for each lecture. You can find our account at the website below:

    www.patreon.com/corconsultrx

    If you have any questions for Cole or me, reach out to us on any of the following:

    Text - 415-943-6116

    • Mike - mcorvino@corconsultrx.com
    • Cole - cswanson@corconsultrx.com
    • AJ - aalford@corconsultrx.com

    Instagram and other social media platforms - @corconsultrx

    This podcast reviews current evidence-based medicine and pharmacy treatment options. This podcast is intended to be used for educational purposes only and is intended for healthcare professionals and students. This podcast is not for patients and not intended as advice or treatment.


    2023 ADA Guideline Updates *ACPE-Accredited* Jan 09, 2023
    Show notes

    On this episode, Cole and I review some of the updates that were published in the 2023 American Diabetes Association guidelines.

    Cole and I are happy to share that our listeners can claim ACPE-accredited continuing education for listening to this podcast episode! We have continued to partner with freeCE.com to provide listeners with the opportunity to claim 1-hour of continuing education credit for select episodes. To earn credit for this episode, visit the following link below to reach the post-activity test for this episode:

    https://legacy.freece.com/Home/CECataLogPodcast

    For existing Unlimited freeCE members, this CE option is included in your membership benefits at no additional cost! Members can simply follow the link above to take the post-test and evaluation for this activity. Use the password ADA2023 (all caps) to unlock the post-test for this episode.

    But if you're not currently a freeCE member, we definitely suggest you explore all the benefits of their Unlimited Membership on their website and earn CE for listening to this podcast. CorConsult Rx listeners can save 15% off the purchase of an unlimited membership by entering the discount code "PODCAST2022" at checkout, or by clicking the following link:

    https://hubs.ly/Q012N0H60

    Thanks for listening!

    We want to give a big thanks to our main sponsor Pyrls. Try out their drug information app today. Visit the website below for a free trial:

    www.pyrls.com/corconsultrx

    If you want to support the podcast, check out our Patreon account. Subscribers will have access to all previous and new pharmacotherapy lectures as well as downloadable PowerPoint slides for each lecture. You can find our account at the website below:

    www.patreon.com/corconsultrx

    If you have any questions for Cole or me, reach out to us on any of the following:

    Text - 415-943-6116

    • Mike - mcorvino@corconsultrx.com
    • Cole - cswanson@corconsultrx.com
    • AJ - aalford@corconsultrx.com

    Instagram and other social media platforms - @corconsultrx

    This podcast reviews current evidence-based medicine and pharmacy treatment options. This podcast is intended to be used for educational purposes only and is intended for healthcare professionals and students. This podcast is not for patients and not intended as advice or treatment.


    Patient Case: Bipolar Disorder and Epilepsy Jan 06, 2023
    Show notes

    Below is the patient case information:

    63-year-old white male.

    Problem List Bipolar II disorder

    Insomnia

    Epilepsy (tonic-clonic seizures)

    Dyslipidemia/hypertriglyceridemia

    Hypertension

    Recent weight gain

    History of hyponatremia

    Diabetes type 2(controlled)

    Medications

    Clonazepam 2 mg QHS

    Risperdal 2 mg twice daily

    Carbamazepine 200 mg twice daily

    Divalproex DR 500 mg three times daily

    Levetiracetam 1000 mg twice daily

    Losartan 100 mg daily

    HCTZ 25 mg daily

    Atorvastatin 40 mg daily

    Fenofibrate 48 mg daily

    Metformin ER 500 mg twice daily

    Vitals:

    Blood pressure is currently 144/86 mmHg

    Lipids:

    LDL-C: 98

    Triglycerides: 245 (down from 423 4 months ago)

    CMP:

    Na+: 133

    K+: 4.1

    eGFR: 95

    All others WNL as well

    CBC:

    Hgb: 10:1 g/dL

    MCV: 73

    Ferritin: 17

    A1c:

    6.9%

    Current Appointment

    The patient has seen multiple neuro and psych providers over the last year.

    The R­­isperdal and divalproex were for the bipolar II disorder. The patient is experiencing depression symptoms. His family notes that he has also been uncharacteristically aggressive lately and becomes agitated over minor issues. His family has recently noticed that while talking with him, his face is grimacing, his tongue will randomly protrude from his lips, as well as other facial movements.

    The clonazepam for insomnia. It helped with insomnia symptoms for a few weeks, but the symptoms are back to pre-treatment baseline. He was taking clonazepam 1 mg 2 hours prior to bed and zopidem 5 mg 30 minutes prior to bedtime. He didn't feel like the zolpidem was working. The clonazepam was increased to 2 mg and the zolpidem was DC'd. He is also complaining of daytime fatigue

    He was recently hospitalized due to hyponatremia. The carbamazepine and levetiracetam were for seizure control. However, the patient has experienced multiple seizures per month for at least the last 3 months.

    Needs better blood pressure and triglyceride control

    Thanks for listening!

    We want to give a big thanks to our main sponsor Pyrls. Try out their drug information app today. Visit the website below for a free trial:

    www.pyrls.com/corconsultrx

    If you want to support the podcast, check out our Patreon account. Subscribers will have access to all previous and new pharmacotherapy lectures as well as downloadable PowerPoint slides for each lecture. You can find our account at the website below:

    www.patreon.com/corconsultrx

    If you have any questions for Cole or me, reach out to us on any of the following:

    Text - 415-943-6116

    Mike - mcorvino@corconsultrx.com Cole - cswanson@corconsultrx.com

    Instagram and other social media platforms - @corconsultrx

    This podcast reviews current evidence-based medicine and pharmacy treatment options. This podcast is intended to be used for educational purposes only and is intended for healthcare professionals and students. This podcast is not for patients and not intended as advice or treatment.


    Insomnia Disorder *ACPE-Accredited* Dec 27, 2022
    Show notes

    On this episode, we discuss the management of insomnia disorder. We review the criteria necessary for an insomnia disorder diagnosis. We then compare and contrast the pharmacotherapy options such as non-benzodiazepine hypnotics, benzodiazepines, anti-depressants, orexin receptor antagonists, and more.

    Cole and I are happy to share that our listeners can claim ACPE-accredited continuing education for listening to this podcast episode! We have continued to partner with freeCE.com to provide listeners with the opportunity to claim 1-hour of continuing education credit for select episodes. To earn credit for this episode, visit the following link below to reach the post-activity test for this episode:

    https://legacy.freece.com/Home/CECataLogPodcast

    For existing Unlimited freeCE members, this CE option is included in your membership benefits at no additional cost! Members can simply follow the link above to take the post-test and evaluation for this activity. Use the password SLEEP (all caps) to unlock the post-test for this episode.

    But if you're not currently a freeCE member, we definitely suggest you explore all the benefits of their Unlimited Membership on their website and earn CE for listening to this podcast. CorConsult Rx listeners can save 15% off the purchase of an unlimited membership by entering the discount code "PODCAST2022" at checkout, or by clicking the following link:

    https://hubs.ly/Q012N0H60

    Thanks for listening!

    We want to give a big thanks to our main sponsor Pyrls. Try out their drug information app today. Visit the website below for a free trial:

    www.pyrls.com/corconsultrx

    If you want to support the podcast, check out our Patreon account. Subscribers will have access to all previous and new pharmacotherapy lectures as well as downloadable PowerPoint slides for each lecture. You can find our account at the website below:

    www.patreon.com/corconsultrx

    If you have any questions for Cole or me, reach out to us on any of the following:

    Text - 415-943-6116

    • Mike - mcorvino@corconsultrx.com
    • Cole - cswanson@corconsultrx.com
    • AJ - aalford@corconsultrx.com

    Instagram and other social media platforms - @corconsultrx

    This podcast reviews current evidence-based medicine and pharmacy treatment options. This podcast is intended to be used for educational purposes only and is intended for healthcare professionals and students. This podcast is not for patients and not intended as advice or treatment.


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