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    Health & Fitness

    Clinical Conversations

    From NEJM Journal Watch, this podcast features lively interviews, concise summaries, and expert commentary that busy clinicians need to stay current and improve patient care.

    Advertise

    Copyright: © 2008-2020 NEJM Journal Watch

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    Latest Episodes:
    Podcast 81: When should you start screening for type 2 diabetes? Apr 02, 2010
    Show notes

    A large-scale computer simulation based on NHANES data plotted the most cost-effective strategy, which turns out to be to start screening before middle age and to repeat every 3 to 5 years. We talk with the first author of a Lancet paper that details the findings.

    Interview-related link:

    • Physician’s First Watch summary of the Lancet paper

    News-related links:

    • 2009 H1N1 makes an unwelcome comeback
    • Health care workers are undervaccinated against 2009 H1N1
    • Checklists lower hospitals’ mortality rates in U.K.
    • Dutasteride doesn’t prevent high-grade prostate tumors
    • Is it reasonable to spend $638,000 to prevent a single MI?

    The post Podcast 81: When should you start screening for type 2 diabetes? first appeared on Clinical Conversations.
    Podcast 80: Bisphosphonates and atypical hip fractures — how large is the risk? Mar 27, 2010
    Show notes

    We talk with three of the academic authors of a New England Journal of Medicine study that pooled data from a few studies in an attempt to examine the possible link between use of bisphosphonates and femoral-shaft fractures.

    Interview-related links:

    • Physician’s First Watch coverage
    • NEJM paper
    • NEJM editorial
    • FDA statement

    News-related links:

    • Aspirin ineffective in preventing miscarriage
    • BNP-guided therapy for heart failure
    • Have kids at risk carry two epi-pens
    • Rotarix contamination

    The post Podcast 80: Bisphosphonates and atypical hip fractures — how large is the risk? first appeared on Clinical Conversations.
    Podcast 79: Prostate cancer, patients’ consultations, and the treatments they receive Mar 19, 2010
    Show notes

    Patients who consult urologists only are more likely to get radical prostatectomy, and those who consult both urologists and radiation oncologists are more likely to get radiation. Those who see internists are more likely to receive watchful waiting. What are all these facts trying to tell us?

    Our conversation is with the principal authors of a study of Medicare data that examines this issue.

    This weeks interview-related link:

    • First Watch coverage of the prostate cancer study

    This week’s news-related links:

    • What’s in that health-reform bill?
    • High-chair hazard prompts recall
    • ACCORD study summary
    • NAVIGATOR study summary
    • Rabies shots lowered to a total of five
    • American Academy of Neurology recommendations on Parkinson’s

    The Journal Watch website

    The post Podcast 79: Prostate cancer, patients’ consultations, and the treatments they receive first appeared on Clinical Conversations.
    Podcast 78: Just what are “comparative effectiveness” studies anyway? Mar 12, 2010
    Show notes

    This week, a conversation with Michael Hochman on his examination of what the major general journals publish in the way of comparative effectiveness studies. He talks about what they are and how to think about that reprint that the drug rep has just dropped off for you.

    Reach us at 617-440-4374, or write to jelia@jwatch.org.

    This week’s interview links:

    • Michael Hochman’s JAMA study
    • The accompanying editorial

    This week’s news links:

    • Blood pressure variability and CVD risk
    • Elective coronary angiography’s low yield
    • Prostate cancer treatments after consultations

    The post Podcast 78: Just what are “comparative effectiveness” studies anyway? first appeared on Clinical Conversations.
    Podcast 77: We revisit a conversation on treating community-acquired pneumonia according to the guidelines (and we’ve got current news). Mar 05, 2010
    Show notes

    Our attempts to get an interview with a researcher were unavailing, so we’ve gone to plan B and repeat a useful look at treating community-acquired pneumonia according to guideline recommendations.

    Please leave comments and complaints at jelia@jwatch.org. You can call and voice these at 1-617-440-4374.

    Interview-related links:

    • Community-Acquired Pneumonia: Guideline-Compliant Treatment Is Better
    • IDSA/ATS guidelines

    News-related links:

    • Evaluating long-term risk via glycated hemoglobin
    • Usefulness of aspirin in lowering risk in patients with abnormal ankle-brachial ratios
    • Carotid endarterectomy versus stenting in patients at high risk
    • Kapidex changes its name to Dexilant

    The post Podcast 77: We revisit a conversation on treating community-acquired pneumonia according to the guidelines (and we’ve got current news). first appeared on Clinical Conversations.
    Podcast 76: On saying “No” to patients’ requests. Feb 27, 2010
    Show notes

    A conversation with the authors of an Archives of Internal Medicine study that examines the best tactics for saying “No” to inappropriate requests.

    Contact me at 1-617-440-4374 or at jelia@jwatch.org.

    Interview-related links:

    • Archives of Internal Medicine abstract
    • Atul Gawande’s New Yorker article

    News-related links:

    • The rosiglitazone (Avandia) controversy
    • Advisory on thiazolidinediones
    • Physicians’ work hours
    • 13-valent pneumococcal vaccine
    • Influenza-vaccination expansion
    • Group CBT for low-back pain

    The post Podcast 76: On saying “No” to patients’ requests. first appeared on Clinical Conversations.
    Podcast 75: Which regimen for hypertension? Feb 19, 2010
    Show notes

    Patients with hypertension at risk for cardiovascular events have done better with an ACE inhibitor-calcium channel blocker combination than with the ACE inhibitor plus hydrochlorothiazide. The ACCOMPLISH investigators have now reported on their analysis of progression-of-nephropathy outcomes in their trial. We interview the first author of the analysis, Dr. George Bakris of the University of Chicago’s Pritzker School of Medicine.

    Interview-related links:

    • NHLBI guidelines on managing hypertension
    • Physician’s First Watch coverage of ACCOMPLISH analysis

    News-related links:

    • FDA warning on long-acting beta agonists
    • Pipe- and cigar-smoking and COPD risk
    • Metformin’s sometimes-offputting aroma
    • Health statistics on the U.S.

    The post Podcast 75: Which regimen for hypertension? first appeared on Clinical Conversations.
    Podcast 74: How two SSRIs apparently interfere with tamoxifen therapy. Feb 12, 2010
    Show notes

    We talk with Dr. Catherine Kelly about her study in BMJ showing serious interference of some SSRIs with tamoxifen therapy in breast cancer. The study was conducted using Canadian provincial databases.

    Reach us at 1-617-440-4374 or by email to jelia@jwatch.org.

    Interview article:

    • BMJ study
    • Physician’s First Watch coverage

    Medical news links:

    • Back pain guidelines
    • Inflammatory bowel disease and venous thromboembolism
    • Automated calling systems

    The post Podcast 74: How two SSRIs apparently interfere with tamoxifen therapy. first appeared on Clinical Conversations.
    Podcast 73: How best to monitor patients on androgen-deprivation therapy for cardiovascular risks? Feb 05, 2010
    Show notes

    A panel of the American Heart Association, the American Cancer Society, and the American Urological Association issued a statement on androgen-deprivation therapy and cardiovascular risk. We’ve got an interview with the chair of the writing committee, Dr. Glenn Levine.

    Interview-related links:

    • Physician’s First Watch coverage of the statement
    • Link to the statement, as published in Circulation

    News-related links:

    • Lancet retracts 1998 paper linking MMR vaccination and autism
    • Use prefilled Sanofi Pasteur N1N1 vaccines before mid-February
    • JAMA study on proteinuria

    If you’d like to contact Clinical Conversations, call 1-617-440-4374 or write to jelia@jwatch.org

    The post Podcast 73: How best to monitor patients on androgen-deprivation therapy for cardiovascular risks? first appeared on Clinical Conversations.
    Podcast 72: A conversation about two new drugs for multiple sclerosis. Jan 29, 2010
    Show notes

    We’ve got Dr. William Carroll this week — we tried last week, but the 13-hour time difference between Boston and Perth just stymied me. Dr. Carroll speaks about his NEJM editorial concerning two new drugs for multiple sclerosis. Both are oral therapies that work to keep lymphocytes at bay in this disease.

    Interview-story link:

    • MS Treatments Said to Offer ‘New Horizon’

    News links:

    • New York Times series on radiation safety
    • Lancet study on glycated hemoglobin levels
    • FDA approval of diabetes drug
    • JNCI study on ovarian cancer symptoms

    The post Podcast 72: A conversation about two new drugs for multiple sclerosis. first appeared on Clinical Conversations.
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