Best Science Medicine Podcast - BS without the BS

Latest Episodes:

Episode 630: Vitamin B12 Deficiency: Monthly shots or daily pills? Oct 11, 2026

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In episode 630, Jamie and James invite Karenn Chan back to the podcast and we go over all the evidence to answer the question, is giving oral vitamin B12 as effective as intramuscular vitamin B12? Lots of people still get these intramuscular shots, but have a listen to the podcast to see if this really still makes sense.

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Tools For Practice
Vitamin B12 Deficiency: Monthly shots or daily pills?

Episode 629: Deprescribing Cholinesterase Inhibitors: Good or bad idea? Sep 23, 2026

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In episode 629, Jamie and James invite Karenn Chan to the podcast for the first time. We go over the evidence for the very important topic of if and when to stop medications for dementia. We’ll give you all the numbers you need to have informed conversations with patients and caregivers of people with dementia. Have a listen and hopefully you will find the discussion useful.

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Tools For Practice
Deprescribing Cholinesterase Inhibitors: Good or bad idea?

Episode 628: Enough Evidence to Put One to Sleep: Cognitive behavioural therapy for insomnia Sep 15, 2026

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In episode 628, Jamie and James invite Jennifer Young back to the podcast to talk about the very important topic of sleep and what to use instead of medications. We go over all the evidence for cognitive behavioural therapy for insomnia and the numbers look pretty impressive. Have a listen and hopefully you will be impressed by the benefit.

Show Notes
1) Tools For Practice
Enough Evidence to Put One to Sleep: Cognitive behavioural therapy for insomnia
2) Great Insomnia Website
Sleepwell

Episode 627: A Tough Nut to Crack: Does oral immunotherapy improve outcomes in peanut allergy? Aug 26, 2026

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In episode 627, Tina and James again invite Danielle Perry and Caitlin Finley back to the podcast to answer the question, in children with peanut allergy, does oral immunotherapy increase peanut tolerance, and what are the adverse effects? It does work, but it is not a cure, so you need to know the numbers and the important context – you’ll get this from this podcast.

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Tools For Practice
A Tough Nut to Crack: Does oral immunotherapy improve outcomes in peanut allergy?

Episode 626: Itchy Beginnings: Can we calm infant eczema? Aug 19, 2026

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In episode 626, Tina and James invite Caitlin Finley and Danielle Perry to the podcast to discuss the evidence for using hydrocortisone or pimecrolimus for atopic dermatitis in patients under the age of 2. They do work, so check out the podcast for all the numbers and the important context.

Show Notes
Tools For Practice
Itchy Beginnings: Can we calm infant eczema?

Episode 625: Blood Pressure Measurement Technique: Meaningful mistakes or minor details? Jul 23, 2026

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In episode 625, Mike K and James invite Danielle Perry and Tony Nickonchuk to the podcast to talk about the evidence around blood pressure measurement techniques. You might be surprised by what does and does not influence blood pressure measurements. Check out the podcast.

Show Notes
Tools For Practice
Blood Pressure Measurement Technique: Meaningful mistakes or minor details?