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    Science

    BBC Inside Science

    A weekly programme that illuminates the mysteries and challenges the controversies behind the science that’s changing our world.

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    Copyright: © (C) BBC 2026

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    Latest Episodes:
    Hyabusa 2 at Ryugu, deadly 1918 flu pandemic; WW2 bombing and ionosphere, teenage brain Sep 27, 2018
    Show notes

    Japan’s Hayabusa-2 spacecraft has arrived after more than a three year journey at the Ryugu asteroid which is just over half a mile long. It has successfully sent probes onto the surface and is sending pictures back to Earth. Gareth Mitchell discusses the achievement with BBC Science Correspondent Jonathan Amos.

    A hundred years ago, the 1918 flu pandemic killed between 50 and 100 million people worldwide and infected around half a billion. Seasonal flu accounts for about 650,000 deaths per year. As this year’s flu season approaches, there are new insights into how the influenza virus causes disease and why some strains like the 1918 one (a subtype of the avian strain H1N1) are so deadly compared with the seasonal kind. In the most serious cases, there’s an extreme immune reaction in the lungs, and people can effectively suffocate. The latest research from the universities of Cambridge and Oxford has uncovered a molecule that might be behind that immune overreaction. Dr Aartjan te Velthuis explains the findings and the implications for novel treatments.

    The massive bombing raids on cities in World War Two lead to terrible human tragedy, Now a historian and a physicist have been looking at how shock waves from some of the major bombing over Berlin caused the upper atmosphere above Slough to wobble. Specifically they’re interested in the layer eighty to a thousand kilometres up that reflects radio waves, the ionosphere. Historian Patrick Major and meteorology expert Christopher Scott, both professors at the University of Reading, tell Gareth about their collaboration and how monitoring changes in the ionosphere today can reveal both man made and natural explosive events.

    And Adam Rutherford talks to Professor Sarah-Jayne Blakemore of UCL about her book, Inventing Ourselves: the Secret Life of the Teenage Brain, the last on this year's shortlist for the Royal Society Insight Investment Science Book Prize.


    Science of Addiction Sep 20, 2018
    Show notes

    The Science Gallery London at Kings College London, right under the Shard, is a brand new venue for the collision of art, science and culture, and its opening exhibition is called Hooked, a series of installations and works by people who have experienced addiction.

    Adam Rutherford explores the neuroscience, the psychology and the epidemiology of addiction; what the latest research says about what addiction is, and how that can help us treat people experiencing addiction. He discusses these questions with psychologist Dr Sally Marlow and neurologist Professor Mitul Mehta who are both at Kings College and have been involved in the exhibition, and Dr Suzi Gage from Liverpool University who studies the epidemiology of addiction. He also talks to the curator of Hooked, Hannah Redler Hawes, and to two of the Science Gallery Young Leaders, Elly Magson and Mandeep Singh, who show him a couple of the exhibits.


    First human drawing, Cycling genes, Oden Arctic expedition, Hello World Sep 13, 2018
    Show notes

    A new discovery of abstract symbolic drawings on a rock has been found in the Blombos Cave, about 300 km east of Cape Town in South Africa. The fragment - which some say looks a bit like a hashtag - puts the date of the earliest drawing at 73,000 years ago. As archaeologist Chris Henshilwood tells Adam Rutherford, the discovery is a "a prime indicator of modern cognition" in our species.

    Nearly half the human genome contains genes that regulate what your organs should be doing at a specific time of day, This has enormous potential importance to the efficacy of drugs - what time of day you take them could be a real issue. John Hogenesch from Cincinnatti Children's Hospital has been studying the genes that cycle with our daily lives. His new database of cyclic genes could help plan the best timing for a host of therapeutic interventions

    Physicist Helen Czerski has been in the Arctic for the last five weeks, aboard the Swedish research vessel and ice breaker Oden. As the expedition comes to a close we hear about the team's attempts to elucidate the driving forces behind the unusual weather patterns around the North Pole.

    Inside Science has been profiling authors shortlisted for the prestigious Royal Society science book prize. This week it's mathematician Hannah Fry's new book, Hello World: How to be human in the Age of Machines. You can hear extracts from it on Book of the Week on Radio 4 all this week too.

    Producer Adrian Washbourne.


    Complexity in Biology Sep 06, 2018
    Show notes

    Adam Rutherford takes the show to Dublin this week, to wrestle with great matters of biological complexity. Trinity College Dublin has organised a mass gathering of some of the world's leading researchers in the life sciences to mark the 75th anniversary of one of the most influential series of lectures in the 20th century. The talks were delivered by the celebrated physicist Erwin Schrodinger in 1943 who applied his mind to a fundamental biological question: what is life? Some of his ideas were an influence on Francis Crick as he worked on the structure of DNA.

    Seventy five years on, Adam is joined by four of the many scientists delivering their own lectures this week. They tackle subjects of complexity in biology, ranging from the origin of complex life, the increasingly messy structure of life's evolutionary tree, the functioning of the human brain as a network of many component parts, and the place of neuroscience discoveries in the building of artificial intelligences.

    The guests are:

    Nick Lane, evolutionary biochemist at University College London, Beth Shapiro, evolutionary geneticist of the University of California Santa Cruz, Danielle Bassett, physicist and neuroscientist at the University of Pennsylvannia, Murray Shanahan, artificial intelligence researcher at Imperial College London and Google's DeepMind

    The podcast version ends with a question and answer session with the show's audience who include a surprise celebrity guest.

    Producer: Andrew Luck-Baker.


    Electronic brain probe; Rural stream biodiversity; Arctic weather research trip; Science book prize Aug 30, 2018
    Show notes

    Scientists have shown how an electronic gadget, implanted in the brain, can detect, treat and even prevent epileptic seizures. Epilepsy is usually treated using anti-epilepsy drugs, but can cause serious side-effects. Researchers at the University of Cambridge, are aiming to create something more specific to the part of the brain with the problem. Professor Malliaras tells Marnie Chesterton about the unique properties of this new implant, which could be used for a range of brain-related conditions from Parkinson’s tremors to brain tumours.

    Many of Britain’s cleaner urban rivers are home to levels of biodiversity not seen for decades. But rural rivers, even in places without pollution, tell a different story. Up in the hills of central Wales, just north of the Brecon Beacons, lies the Llyn Brianne observatory and its surrounding system of beautiful streams. Professor Steve Ormerod from Cardiff University has been taking stock of the dwindling number of specialist invertebrates and the subtle ways the decline is happening which points to an extinction crisis that has gone unnoticed.

    Marnie Chesterton checks in with bubble physicist Dr Helen Czerski. She’s part of a team of researchers aboard the icebreaker Oden research vessel, which is trying to understand arctic weather patterns and how the contents of open water between ice flows influence cloud behaviour. It’s a race against time to gather data before any water refreezes as the arctic winter approaches.

    Inside Science has been profiling authors shortlisted for the prestigious Royal Society science book prize. This week it’s the turn of materials scientist Mark Miadownik, His new book “Liquid: The delightful and dangerous substances that flow through our lives” is about fluids and how their particular properties allow life to flourish.

    Presenter Marnie Chesterton

    Producer: Adrian Washbourne


    Cavendish banana survival; Guillemot egg shape; Unexpected Truth About Animals; Tambora's rainstorm Aug 23, 2018
    Show notes

    The last banana you probably ate was a type called Cavendish. But this, our last commercially viable variety is under severe threat, as the fungus, called Tropical Race 4, is laying waste to swathes of Cavendish banana plants across China, Asia and Australia. Recently, scientists & horticulturalists gathered in Istanbul to discuss the best ways to fight the threat. Professor James Dale from the Institute of Future Environments at the University of Queensland has been conducting successful field trials in previously infected areas with impressive results. Could gene editing provide the solution?

    The extraordinary shape of the guillemot egg is one of ornithology’s great mysteries. This seabird lays something twice the size of a hen’s egg, which looks a bit like an obelisk, blue, speckled and weirdly elongated at one end, with almost flat sides. There have been a handful of theories to explain why it’s evolved. Professor of behaviour and evolution Tim Birkhead, at the University of Sheffield shows in his new research that the answer lies in allowing the birds to successfully breed on the steep slopes of cliff ledges.

    Marnie Chesterton meets the next in Inside Science’s series of writers shortlisted for the very prestigious Royal Society’s Book Prize : Lucy Cooke, zoologist, author and broadcaster discusses The Unexpected Truth About Animals which flies the flag for some of the lessons learnt from mistakes made in understanding animal behaviour.

    Could the Tambora volcanic eruption in April 1815 be responsible for Napoleon’s defeat at Waterloo? A rain-soaked battlefield in June 1815, stopped Napoleon deploying his military might although many have questioned how a volcano could have such an effect on the weather so soon. How was it to blame for a Belgian rainstorm just several weeks after the end of the eruption? Dr Matt Genge from Imperial College, in a new paper out this week, says the answer lies in the phenomenon known as electrostatic levitation.

    Presenter: Marnie Chesterton Producer: Adrian Washbourne


    Capturing greenhouse gas, Beating heart failure with beetroot, Why elephants don't get cancer, Exactly - a history of precision Aug 16, 2018
    Show notes

    Researchers have found a way to produce a naturally occurring mineral, magnesite, in a lab, that can absorb CO2 from the atmosphere, offering a potential strategy for tackling climate change. They've accelerated a process that normally takes thousands of years to a matter of days, using panels made from tiny balls of polystyrene. Gareth Mitchell meets Ian Power of Trent University in Ontario who led the research. Could this be a viable technology for tackling global warming and carbon dioxide in the atmosphere?

    What if something as natural as beetroot - or specifically defined doses of beetroot juice - could help alleviate cardiovascular disease and improve the pumping function of failing hearts? That's the idea behind a major trial underway at the Barts Heart Hospital and Queen Mary University in London. Amrita Ahluwalia, co-Director of the William Harvey Research Institute and Christopher Primus a specialist in heart failure, are interrogating the natural nitrates in foods like beetroot and how they could be beneficial to our cardiovascular system.

    Cells in our bodies can go wrong and end up proliferating into cancers. Intuition might say the bigger something is, the more cells it has and thus, greater is its risk of developing cancer. But elephants have somehow re-awakened a gene that kills cells that could be cancerous before they have time to cause any damage. Vincent Lynch of the University of Chicago has been looking at the genetics that keeps these giants virtually, immune which could hold clues for tackling cancers in humans.

    And we hear from Simon Winchester, the next in our series of interviews with the shortlisted authors for this year's Royal Society Insight Investment Science Book Prize. Exactly, is an intriguing history of precision, the search for ever greater engineering accuracy and how it changed the world.

    Presenter: Gareth Mitchell Producer: Adrian Washbourne.


    New Horizons' next mission, Helium at 150, The Beautiful Cure, Oden arctic expedition Aug 09, 2018
    Show notes

    Astronomers this week have been warming up for an encounter as far from the Sun as ever attempted. It's the finale of the New Horizons mission which successfully passed Pluto in 2015 and is now on its way to Ultima Thule - a Kuiper belt object on the edge of the solar system. Marc Buie is just back from Senegal where he and a team of fellow astronomers have been observing this ancient rock to get a final look at its size and shape, before the momentous flyby on Jan 1st 2019. He explains why the encounter will be so valuable in unlocking key secrets in the formation of our solar system.

    It's the 150th birthday of the discovery of helium, which, after hydrogen is the second most abundant element in the universe. It's surprisingly rare on Earth, but it makes up much of the content of the gas giants in our local neighbourhood, Jupiter and Saturn. Adam Rutherford hears from particle physicist and Science Museum curator Harry Cliff on how it was first discovered through a telescope rather than in a lab, and Jessica Spake of Exeter University who after an 18-year search has used similar techniques to discover helium around an exoplanet 200 light-years away.

    We hear from scientist and author Dan Davis from the University of Manchester, the next in our preview of authors shortlisted for this year's Royal Society book prize. The Beautiful Cure, is the rollicking story of how the intricate immune system came to be understood.

    And there's an update from physicist Helen Czerski. She's part of a 40-strong team of field scientists on board the Oden, a Swedish ice breaker and research ship. They're set to find a suitable iceberg, and moor to get to grips with the factors that guide the arctic weather patterns.

    Producer: Adrian Washbourne.


    Parker solar probe, Diversity in the lab, Royal Society book prize, Arctic circle weather Aug 02, 2018
    Show notes

    The sun still has many mysterious properties. The Parker Solar Probe, launched next week will be the closest a spacecraft has ever flown to our star. It's a mission that's been on the drawing board for decades which space scientists have only dreamt of. It will fly into the mysterious solar corona, where so much of the action at 3 million degrees centigrade takes place. Nicola Fox from Johns Hopkins University is the Parker Probe Project Scientist. Adam Rutherford speaks to her from Cape Canaveral, where they are making the final adjustments for the most ambitious journey ever, to the Sun.

    We meet two scientists who are making a real difference in promoting diversity and equality in the lab. Physicist Jess Wade has been chipping away at this issue, most recently in a heroic project to write up a Wikipedia entry for a scientist who is also a woman every day for the last 270 days and counting. Emma Chapman is an astrophysicist, and last month won the prestigious Royal Society Athena Prize for her work in driving policy changes about sexual harassment at universities.

    Today the shortlist of the most prestigious of the literary prizes for the sciences was announced - the Royal Society Insight Investment Science Book Prize. This is the 31st prize, and previous winners are a who's who in truly great science writing. Frances Ashcroft, Professor of Physiology at Oxford is the chair of the judges and discusses the books they have selected.

    Physicist Helen Czerski and 40 colleagues are now aboard the Oden, a Swedish icebreaker and scientific research vessel that set sail earlier this week. They are en route to spend a month anchored to arctic sea ice to elucidate the mysterious behaviour of arctic weather. Before she set off she gave Adam Rutherford a preview of the research trip.

    Producer Adrian Washbourne.


    Liquid water on Mars, Early embryo development, Earth Biogenome Project, Marine wilderness Jul 26, 2018
    Show notes

    The European Space Agency's satellite Mars Express has identified what we think is a subterranean lake of liquid near the south pole of the red planet. The question of water on Mars has been around for years, and we've known about water ice, and there's been the possibility of seasonal flowing water on Mars for a while. But if this result is right, this is the first case of a substantial stable body of liquid water on Mars. Adam Rutherford talks to Roberto Orosei of the Radio Astronomy Institute in Bologna whose team made the discovery. Where should scientists be directing their efforts next in the light of this new finding? We hear from NASA's Chief Scientist Jim Green.

    We've been growing embryonic cells in petri dishes for a few years now, to try to fill in the gaps in our understanding of early development, but the tissue that grows never really resembles an actual embryo. Magdalena Zernicka Goetz is a developmental biologist from Cambridge University and in a paper out this week has leapt over this hurdle in developmental biology using three types of stem cell, which - unlike previous efforts - push a ball of cells to becoming an embryo, which could help us understand why pregnancy can fail.

    The Earth Biogenome Project aims to sequence the DNA of all the planet's eukaryotes, some 1.5 million known species including all known plants, animals and single-celled organisms. The project will take 10 years to complete and cost an estimated $4.7 billion. Harris Lewin from UC Davis is spearheading this scheme. How will he meet his ambition to curate all the DNA of life on Earth?

    For the first time, scientists have assessed how much of the seas are untouched by the impact of human activity. They're referred to as Marine Wilderness, and qualify as such by being relatively untouched by things like fishing, pollution or agricultural run-off. According to the survey, published today, only 13% of the world's oceans remain as wilderness. James Watson from the University of Queensland discusss the action that needs to be taken if these precious ecological areas are to survive.

    Producer : Adrian Washbourne.


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