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    Technology

    Astral Codex Ten Podcast

    The official audio version of Astral Codex Ten, with an archive of posts from Slate Star Codex. It’s just me reading Scott Alexander’s blog posts.

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    Latest Episodes:
    Puritan Spotting Mar 14, 2019
    Show notes

    [Related to: Book Review: Albion's Seed] [Epistemic status: Not too serious]

    I realize I've been confusing everyone with my use of the word "Puritan". When I say "That guy is so Puritan!" people object "But he's not religious!" or "He doesn't hate fun!"

    I don't know what the real word for the category I'm calling "Puritan" is. Words like "Yankee", "Boston Brahmin", or "Transcendentalist" are close, but none of them really work. "Eccentric overeducated hypercompetent contrarian early American who takes morality very seriously" is good, but too long.

    Instead of explaining further, here's a (more than half-joking) Puritan checklist. Maximum one item per red box.

    The obvious next step is to rank historical figures by Puritanism Points. Here are the top five famous Americans I can find, as per Wikipedia:

    #5: SAMUEL MORSE Samuel Morse was born to Pastor (+3) Jedediah (+1) Morse and his wife Elizabeth (+1) in Charlestown, Massachusetts (+3), the eldest of six children (+3). After attending Yale (+1), he pursued a career as an internationally famous painter. But when his wife Lucretia (+1) fell sick, he was unable to receive the news in time to go home to her before she died, inspiring him to change careers during mid-life (+3) and become an inventor. He spent his life perfecting the telegraph (+1), but also invented an automatic sculpture-making machine (+3). In later life, he switched careers again, becoming an anti-Catholic activist (+1); he ran for Mayor of New York on an anti-Catholic platform, and wrote anti-Catholic pamphlets like A Foreign Conspiracy Against The Liberties Of The United States (+1). He was also a well-known philanthropist (+3). His hairstyle looked like this (+3).

    Total Puritanism = 28


    Book Review: Albion's Seed [Classic] Mar 13, 2019
    Show notes

    I.

    Albion's Seed by David Fischer is a history professor's nine-hundred-page treatise on patterns of early immigration to the Eastern United States. It's not light reading and not the sort of thing I would normally pick up. I read it anyway on the advice of people who kept telling me it explains everything about America. And it sort of does.

    In school, we tend to think of the original American colonists as "Englishmen", a maximally non-diverse group who form the background for all of the diversity and ethnic conflict to come later. Fischer's thesis is the opposite. Different parts of the country were settled by very different groups of Englishmen with different regional backgrounds, religions, social classes, and philosophies. The colonization process essentially extracted a single stratum of English society, isolated it from all the others, and then plunked it down on its own somewhere in the Eastern US.

    I used to play Alpha Centauri, a computer game about the colonization of its namesake star system. One of the dynamics that made it so interesting was its backstory, where a Puerto Rican survivalist, an African plutocrat, and other colorful characters organized their own colonial expeditions and competed to seize territory and resources. You got to explore not only the settlement of a new world, but the settlement of a new world by societies dominated by extreme founder effects. What kind of weird pathologies and wonderful innovations do you get when a group of overly romantic Scottish environmentalists is allowed to develop on its own trajectory free of all non-overly-romantic-Scottish-environmentalist influences? Albion's Seed argues that this is basically the process that formed several early US states.

    Fischer describes four of these migrations: the Puritans to New England in the 1620s, the Cavaliers to Virginia in the 1640s, the Quakers to Pennsylvania in the 1670s, and the Borderers to Appalachia in the 1700s.

    II.

    A: The Puritans

    I hear about these people every Thanksgiving, then never think about them again for the next 364 days. They were a Calvinist sect that dissented against the Church of England and followed their own brand of dour, industrious, fun-hating Christianity. Most of them were from East Anglia, the part of England just northeast of London. They came to America partly because they felt persecuted, but mostly because they thought England was full of sin and they were at risk of absorbing the sin by osmosis if they didn't get away quick and build something better. They really liked "city on a hill" metaphors.

    I knew about the Mayflower, I knew about the black hats and silly shoes, I even knew about the time Squanto threatened to release a bioweapon buried under Plymouth Rock that would bring about the apocalypse. But I didn't know that the Puritan migration to America was basically a eugenicist's wet dream.

    Much like eg Unitarians today, the Puritans were a religious group that drew disproportionately from the most educated and education-obsessed parts of the English populace. Literacy among immigrants to Massachusetts was twice as high as the English average, and in an age when the vast majority of Europeans were farmers most immigrants to Massachusetts were skilled craftsmen or scholars. And the Puritan "homeland" of East Anglia was a an unusually intellectual place, with strong influences from Dutch and Continental trade; historian Havelock Ellis finds that it "accounts for a much larger proportion of literary, scientific, and intellectual achievement than any other part of England."

    Furthermore, only the best Puritans were allowed to go to Massachusetts; Fischer writes that "it may have been the only English colony that required some of its immigrants to submit letters of recommendation" and that "those who did not fit in were banished to other colonies and sent back to England". Puritan "headhunters" went back to England to recruit "godly men" and "honest men" who "must not be of the poorer sort".


    Ketamine: Now by Prescription Mar 12, 2019
    Show notes

    Last week the FDA approved esketamine for treatment-resistant depression.

    Let's review how the pharmaceutical industry works: a company discovers and patents a potentially exciting new drug. They spend tens of millions of dollars proving safety and efficacy to the FDA. The FDA rewards them with a 10ish year monopoly on the drug, during which they can charge whatever ridiculous price they want. This isn't a great system, but at least we get new medicines sometimes.

    Occasionally people discover that an existing chemical treats an illness, without the chemical having been discovered and patented by a pharmaceutical company. In this case, whoever spends tens of millions of dollars proving it works to the FDA may not get a monopoly on the drug and the right to sell it for ridiculous prices. So nobody spends tens of millions of dollars proving it works to the FDA, and so it risks never getting approved.

    The usual solution is for some pharma company to make some tiny irrelevant change to the existing chemical, and patent this new chemical as an "exciting discovery" they just made. Everyone goes along with the ruse, the company spends tens of millions of dollars pushing it through FDA trials, it gets approved, and they charge ridiculous prices for ten years. I wouldn't quite call this "the system works", but again, at least we get new medicines.

    Twenty years ago, people noticed that ketamine treated depression. Alas, ketamine already existed – it's an anaesthetic and a popular recreational drug – so pharma companies couldn't patent it and fund FDA trials, so it couldn't get approved by the FDA for depression. A few renegade doctors started setting up ketamine clinics, where they used the existing approval of ketamine for anaesthesia as an excuse to give it to depressed people. But because this indication was not FDA-approved, insurance companies didn't have to cover it. This created a really embarrassing situation for the medical system: everyone secretly knows ketamine is one of the most effective antidepressants, but officially it's not an antidepressant at all, and mainstream providers won't give it to you.

    The pharmaceutical industry has lobbyists in Heaven. Does this surprise you? Of course they do. A Power bribed here, a Principality flattered there, and eventually their petitions reach the ears of God Himself. This is the only possible explanation for stereochemistry, a quirk of nature where many organic chemicals come in "left-handed" and "right-handed" versions. The details don't matter, beyond that if you have a chemical that you can't patent, you can take the left-handed (or right-handed) version, and legally pretend that now it is a different chemical which you can patent. And so we got "esketamine".


    Prospiracy Theories Mar 06, 2019
    Show notes

    [Title from this unrelated story or this unrelated essay]

    Last week I wrote about how conspiracy theories spread so much faster on Facebook than debunkings of those same theories. A few commenters chimed in to say that of course this was true, the conspiracy theories had evolved into an almost-perfect form for exploiting cognitive biases and the pressures of social media. Debunkings and true beliefs couldn't copy that process, so they were losing out.

    This sounded like a challenge, so here you go:


    Meaningful Mar 02, 2019
    Show notes

    [With apologies to Putnam, Pope, and all of you]

    Two children are reading a text written by an AI:

    The hobbits splashed water in each other's faces until they were both sopping wet

    One child says to the other "Wow! After reading some text, the AI understands what water is!"

    The second child says "It doesn't really understand."

    The first child says "Sure it does! It understands that water is the sort of substance that splashes. It understands that people who are splashed with water get wet. What else is left to understand?"

    The second child says "All it understands is relationships between words. None of the words connect to reality. It doesn't have any internal concept of what water looks like or how it feels to be wet. Only that the letters W-A-T-E-R, when appearing near the letters S-P-L-A-S-H bear a certain statistical relationship to the letters W-E-T."

    The first child starts to cry.

    Two chemists are watching the children argue with each other. The first chemist says "Wow! After seeing an AI, these kids can debate the nature of water!"

    The second chemist says "Ironic, isn't it? After all, the children themselves don't understand what water is! Water is two hydrogen atoms plus one oxygen atom, and neither of them know!"

    The first chemist answers "Come on. The child knows enough about water to say she understands it. She knows what it looks like. She knows what it tastes like. That's pretty much the basics of water."

    The second chemist answers "Those are just relationships between pieces of sense-data. The child knows that (visual perception of clear shiny thing) = (tactile perception of cold wetness) = (gustatory perception of refreshingness). And she can predict statistical relationships, like that if she sees someone throw a bucket of (visual perception of clear shiny thing) at her, she will soon feel (tactile perception of cold miserable sopping wetness). She uses the word "water" as a concept-hook that links all of these relationships together and makes predicting the world much easier. But no matter how well she masters these facts, she can never connect them to H2O or any other real chemical facts about the world beyond mere sense-data."


    In Mod We Trust Mar 01, 2019
    Show notes

    The Verge writes a story (an exposé?) on the Facebook-moderation industry.

    It goes through the standard ways it maltreats its employees: low pay, limited bathroom breaks, awful managers – and then into some not-so-standard ones. Mods have to read (or watch) all of the worst things people post on Facebook, from conspiracy theories to snuff videos. The story talks about the psychological trauma this inflicts:

    It's an environment where workers cope by telling dark jokes about committing suicide, then smoke weed during breaks to numb their emotions…where employees, desperate for a dopamine rush amid the misery, have been found having sex inside stairwells and a room reserved for lactating mothers…

    It's a place where the conspiracy videos and memes that they see each day gradually lead them to embrace fringe views. One auditor walks the floor promoting the idea that the Earth is flat. A former employee told me he has begun to question certain aspects of the Holocaust. Another former employee, who told me he has mapped every escape route out of his house and sleeps with a gun at his side, said: "I no longer believe 9/11 was a terrorist attack.

    One of the commenters on Reddit asked "Has this guy ever worked in a restaurant?" and, uh, fair. I don't want to speculate on how much weed-smoking or sex-in-stairwell-having is due to a psychological reaction to the trauma of awful Facebook material vs. ordinary shenanigans. But it sure does seem traumatic.

    Other than that, the article caught my attention for a few reasons.

    First, because I recently wrote a post that was a little dismissive of moderators, and made it sound like an easy problem. I think the version I described – moderation of a single website's text-only comment section – is an easi-er problem than moderating all of Facebook and whatever horrible snuff videos people post there. But if any Facebook moderators, or anyone else in a similar situation, read that post and thought I was selling them short, I'm sorry.


    Rule Thinkers In, Not Out Feb 28, 2019
    Show notes

    Imagine a black box which, when you pressed a button, would generate a scientific hypothesis. 50% of its hypotheses are false; 50% are true hypotheses as game-changing and elegant as relativity. Even despite the error rate, it's easy to see this box would quickly surpass space capsules, da Vinci paintings, and printer ink cartridges to become the most valuable object in the world. Scientific progress on demand, and all you have to do is test some stuff to see if it's true? I don't want to devalue experimentalists. They do great work. But it's appropriate that Einstein is more famous than Eddington. If you took away Eddington, someone else would have tested relativity; the bottleneck is in Einsteins. Einstein-in-a-box at the cost of requiring two Eddingtons per insight is a heck of a deal.

    What if the box had only a 10% success rate? A 1% success rate? My guess is: still most valuable object in the world. Even an 0.1% success rate seems pretty good, considering (what if we ask the box for cancer cures, then test them all on lab rats and volunteers?) You have to go pretty low before the box stops being great.

    I thought about this after reading this list of geniuses with terrible ideas. Linus Pauling thought Vitamin C cured everything. Isaac Newton spent half his time working on weird Bible codes. Nikola Tesla pursued mad energy beams that couldn't work. Lynn Margulis revolutionized cell biology by discovering mitochondrial endosymbiosis, but was also a 9-11 truther and doubted HIV caused AIDS. Et cetera. Obviously this should happen. Genius often involves coming up with an outrageous idea contrary to conventional wisdom and pursuing it obsessively despite naysayers. But nobody can have a 100% success rate. People who do this successfully sometimes should also fail at it sometimes, just because they're the kind of person who attempts it at all. Not everyone fails. Einstein seems to have batted a perfect 1000 (unless you count his support for socialism). But failure shouldn't surprise us.


    Wage Stagnation: Much More Than You Wanted to Know Feb 28, 2019
    Show notes

    [Epistemic status: I am basing this on widely-accepted published research, but I can't guarantee I've understood the research right or managed to emphasize/believe the right people. Some light editing to bring in important points people raised in the comments.]

    You all know this graph:

    Median wages tracked productivity until 1973, then stopped. Productivity kept growing, but wages remained stagnant.

    This is called "wage decoupling". Sometimes people talk about wages decoupling from GDP, or from GDP per capita, but it all works out pretty much the same way. Increasing growth no longer produces increasing wages for ordinary workers.

    Is this true? If so, why?

    1. What Does The Story Look Like Across Other Countries And Time Periods?

    Here's a broader look, from 1800 on:

    It no longer seems like a law of nature that productivity and wages are coupled before 1973. They seem to uncouple and recouple several times, with all the previous graphs' starting point in 1950 being a period of unusual coupledness. Still, the modern uncoupling seems much bigger than anything that's happened before.

    What about other countries? This graph is for the UK (you can tell because it spells "labor" as "labour")

    It looks similar, except that the decoupling starts around 1990 instead of around 1973.

    And here's Europe:

    This is only from 1999 on, so it's not that helpful. But it does show that even in this short period, France remains coupled, Germany is decoupled, Spain is…doing whatever Spain is doing, and Italy is so pathetic that the problem never even comes up. Overall not sure what to think about these.

    2. Could Apparent Wage Decoupling Be Because Of Health Insurance?

    Along with wages, workers are compensated in benefits like health insurance. Since health insurance has skyrocketed in price, this means total worker compensation has gone up much more than wages have. This could mean workers are really getting compensated much more, even though they're being paid the same amount of money. This view has sometimes been associated with economist Glenn Hubbard.

    There are a few lines of argument that suggest it's not true.

    First, wage growth has been worst for the lowest-paid workers. But the lowest-paid workers don't usually get insurance at all.


    RIP Culture War Thread Feb 23, 2019
    Show notes

    [This post is having major technical issues. Some comments may not be appearing. If you can't comment, please say so on the subreddit.]

    I. I Come To Praise Caesar, Not To Bury Him

    Several years ago, an SSC reader made an r/slatestarcodex subreddit for discussion of blog posts here and related topics. As per the usual process, the topics that generated the strongest emotions – Trump, gender, race, the communist menace, the fascist menace, etc – started taking over. The moderators (and I had been added as an honorary mod at the time) decreed that all discussion of these topics should be corralled into one thread so that nobody had to read them unless they really wanted to. This achieved its desired goal: most of the subreddit went back to being about cognitive science and medicine and other less-polarizing stuff.

    Unexpectedly, the restriction to one thread kick-started the culture war discussions rather than toning them down. The thread started getting thousands of comments per week, some from people who had never even heard of this blog and had just wandered in from elsewhere on Reddit. It became its own community, with different norms and different members from the rest of the board.

    I expected this to go badly. It kind of did; no politics discussion area ever goes really well. There were some of the usual flame wars, point-scoring, and fanatics. I will be honest and admit I rarely read the thread myself.

    But in between all of that, there was some really impressive analysis, some good discussion, and even a few changed minds. Some testimonials from participants:

    For all its awfulness there really is something special about the CW thread. There are conversations that have happened there that cannot be replicated elsewhere. Someone mentioned its accidental brilliance and I think that's right—it catches a wonderful conversational quality I've never seen on the Internet, and I've been on the Internet since the 90s – werttrew

    I feel that, while practically ever criticism of the CW thread I have ever read is true, it is still the best and most civil culture war-related forum for conversation I have seen. And I find the best-of roundup an absolute must-read every week – yrrosimyarin


    My Plagiarism Feb 22, 2019
    Show notes

    I was going back over yesterday's post, and something sounded familiar about this paragraph:

    A very careless plagiarist takes someone else's work and copies it verbatim: "The mitochondria is the powerhouse of the cell". A more careful plagiarist takes the work and changes a few words around: "The mitochondria is the energy dynamo of the cell". A plagiarist who is more careful still changes the entire sentence structure: "In cells, mitochondria are the energy dynamos". The most careful plagiarists change everything except the underlying concept, which they grasp at so deep a level that they can put it in whatever words they want – at which point it is no longer called plagiarism.

    After rereading it a few times, it hit me. A few days ago, I'd come across this quote from Miss Manners:

    There are three possible parts to a date, of which at least two must be offered: entertainment, food, and affection. It is customary to begin a series of dates with a great deal of entertainment, a moderate amount of food, and the merest suggestion of affection. As the amount of affection increases, the entertainment can be reduced proportionately. When the affection IS the entertainment, we no longer call it dating.

    I laughed at it, I thought it was great, and I stored it in my head as the sort of thing I should quote at some point in order to sound witty.

    And although I wasn't consciously thinking about it at the time, I'm sure the last sentence of my paragraph comes from the last sentence of Miss Manners'. It would be easy to dismiss it as a coincidence, it probably seems like a coincidence to you, I can't explain how I know that the one comes from the other, but when I replay in my mind the process that made me write that, it's obvious that it did.


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