Stay ConnectedHear from a variety of experts on all things neuromuscular & electrodiagnostic medicine. Learn new science, hear expert perspectives, and join the conversation!
AANEM podcasts are intended for educational purposes only. The views expressed are those of the speakers and do not necessarily reflect the views or policies of AANEM. Podcast content should not be interpreted as clinical, legal, or reimbursement advice. Contact aanem@aanem.org with any questions or concerns.
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Tune in to this episode to learn important pearls about performing pediatric EMG as Drs. Rubin and Jarrar talk through an interesting case of a young patient with progressive weakness.
Kelly Gwathmey, MD facilitates a debate between Christina Fournier, MD and Shafeeq Ladha, MD: Should Serum Neurofilament Light Chain or NfL be Incorporated into Routine ALS Clinical Practice?
Shawn Jorgenson, MD facilitates a debate between Larry Robinson, MD and Jeff Strakowski, MD: Should a Combined Sensory Index be Used in Every Case of Suspected Carpal Tunnel Syndrome?
What are you most thankful for this year? Is it listening to these educational Lessons from the Lab? If so, you are in luck – enjoy this Thanksgiving edition of Lessons from the Lab as Drs. Rubin and Del Toro talk turkey, stuffing, and nerves!
Carrie Ford, CNCT specialist II facilitates a debate between Michael Andary, MD and Nassim Rad, MD on the balance between diagnostic testing and clinical care — when it’s appropriate to add an Evaluation and Management component to the EMG, and when it’s more appropriate to keep the study purely diagnostic.
If you missed this engaging, Lessons at the AANEM in San Francisco, you are in luck . . . join this “replay” of the lively panel and audience discussion about a woman with sudden painless hand weakness. Does this woman’s clinical presentation, EDX findings, and image make sense? Should you always perform Babinski testing on ever patient in the EMG laboratory? Enjoy this educational discussion and debate.
Do you think that patients that complain of shoulder pain should always be evaluated with an EMG? Perhaps not, but not all shoulder pain is orthopedic in nature. Tune in to this episode to see how EMG can help when the cause of shoulder pain may not be obvious?
Chilvana Patel, MD interviews Devon Rubin, MD on "Lessons Learned in the EMG Lab: Elevating EMG Practice Through International Exchange." Dr. Rubin will be sharing his extensive experience in EMG education and collaborative practice across the countries. That effort is the exchange of best practices and the development of collaborations that ultimately improve patient care and promote health equity worldwide.
Do you have questions about neuralgic amyotrophy? In this episode, Shawn Jorgensen, MD will check in with Joelle Gabet, MD, the lead author of the recent review of neuralgic amyotrophy in Muscle and Nerve. She will review recent updates in the clinical presentation, electrodiagnosis, imaging, and treatment of this disorder with a focus on evolving aspects, including imaging findings and surgical and non-surgical implications.
Carrie Ford, CNCT interviews Clark Moser, MD, ABEM, ABPN on "Electromyography Referrals: Principles and Practices for Optimizing EMG Orders ". This podcast is for neurologists, PMRs, orthopedists, PCPs, NPs, PAs, and residents who refer patients for EMG and NCS. It also helps NCS technologists understand the clinical intent behind each referral—guided by the EMGer’s diagnostic focus. This episode offers practical strategies for improving the quality of the EMG referrals by treating each order as a focused clinical study. We review what the EMG evaluates—nerve and muscle function—and how to understand results in terms of localization and severity. Listeners will learn to move beyond vague referral terms like “weakness,” “pain,” or “paresthesia” and instead indicate in the EMG order what specific neuromuscular or electrodiagnostic question they want answered.
In this AANEM session, Chilvana Patel, MD moderates a discussion with Pushpa Narayanswami, MD, Nicholas Silvestri, MD, and Kelly Gwathmey, MD on the evolving treatment landscape in myasthenia gravis (MG). The panel reviews the use of targeted therapies in women of childbearing age with myasthenia gravis, alongside guidance for perioperative care before elective surgery. Through illustrative patient cases, the experts provide insight into practical challenges and emerging opportunities in tailoring advanced immunotherapies to individual patient needs.
Chilvana Patel, MD is hosting a case-based panel discussion titled "Evolving Therapeutic Horizons in Myasthenia Gravis: Expert Perspectives on Targeted Therapies - Part 1." She will engage with renowned neuromuscular specialists—Pushpa Narayanaswami, MD, Nicholas Silvestri, MD, and Kelly Gwathmey, MD—to explore real-world cases and discuss the latest advances in targeted treatment options for Myasthenia Gravis.
Have you ever experienced tingling after running a marathon? Is marathon running good for your nerves? Tune in to this episode and listen to Drs. Rubin and Shahrizaila discuss an unusual case to help you decide whether or not to take up running.
In this episode, Dr. Nadia Khalil interviews Dr. Nathaniel Robbins, the Director of the Autonomic and Small Fiber Neuropathy program at Mass General Brigham, on POTS. In this episode, they review the diagnostic criteria, clinical presentation, differential diagnosis, adjunctive testing, and management.
Do you know what neuromuscular condition Spock from Star Trek may have had? Tune in to this Lessons from the Lab to learn!
In this AANEM podcast, Chilvana Patel, MD, interviews Devin Rubin, MD, and Nortina Shahrizaila, PhD, about global disparities in EMG and nerve conduction study training. They discuss challenges such as inconsistent educational program standards, limited resources, and lack of mentorship, especially in developing countries. This podcast covers the current efforts to improve access to hands-on training and standardized education.
Dr. Kelly Gwathmey interviews Dr. Corey Bacher from the University of Toronto, Dr. Charles Kassardjian from the University of Toronto, both in Toronto, Ontario, Canada. We also have Dr. Ruple Laughlin from the Mayo Clinic in Rochester, Minnesota, and Dr. Puspha Narayanswami from Beth Israel Deaconess Medical Center in Boston, Massachusetts. They will all be discussing recommendations for monitoring and managing glucocorticoid related systemic complications from the recently published: “International Consensus Guidance for the Management of Glucocorticoid Related Complications in Neuromuscular Disease."
This AANEM podcast features Dr. Joome Suh, a neurologist and neuromuscular specialist at Brigham and Women's Hospital, interviewed by neuromuscular fellow Dr. Nadia Khalil. They discuss HMG-CoA reductase immune-mediated necrotizing myopathy (HMGCR IMNM), a rare autoimmune muscle disease often associated with statin use. The discussion covers clinical presentation, epidemiologic considerations, histopathologic findings, and treatment approaches, with special focus on Dr. Suh’s recent research published in Muscle and Nerve with co-author Dr. Anthony Amato. Their study found that patients receiving maintenance IVIG as part of their regimen were more likely to have a normal CK at 6 months and the daily prednisone-equivalent was lower. A sub-group analysis suggested IVIG as monotherapy is effective.
How did you fare on your March Madness brackets? Did you win your EMG lab pool? Did you pick any upsets? Tune in and you will be sure to win this Lessons from the Lab March Madness bracket. It’s full of surprises and successes, and you won’t be “upset".
In this podcast, host Carrie Ford, CNCT, R.NCS.T., interviews 4 nerve conduction technologists: Candy Dolan, CNCT, R.NCS.T, R.EEGT, Pati Ramsey, CNCT, R.NCS.T, Nicole Wiley, CNCT, and Nathaniel Dickey, CNCT.
They discuss how AANEM transformed their field by establishing the Certified Nerve Conduction Technologist (CNCT) credential in 2011. The technologists share insights about AANEM membership benefits, certification challenges, employer support and offer advice to newcomers on mentorship and continuous learning. All emphasize the importance of certification and community involvement in maintaining professional standards.
The podcast explores the AANEM Training Program Partnership (TPP), an educational resource designed for neurology and PM&R training programs. The discussion features current neuromuscular fellows, Sukhraj Gill & Praveen Attele, along with hosts Bhaskar Roy (an associate professor at Yale) and Carrie Ford (a technologist at University of Utah).
Enjoy this Valentine’s Day edition of Lessons From the Lab! Drs. Rubin and Levin work through a case with some twists and turns and a variety of teaching points – it’s just like not knowing what you are going to get when you open a box of Valentine’s Day chocolates!
Grab your hot chocolate and cozy up to your fireplace as you warm up with an educational discussion about a patient who lost his voice. Drs. Rubin and Munin will help teach you how to help patients find their voice (or at least find some muscles contributing to their voice with needle EMG) as they figure out the best way to approach this patient.
In this AANEM podcast, Dr. Stino interviews Dr. Allen on the groundbreaking ADHERE study, published in Lancet Neurology in 2024, which investigated efgartigimod for treating chronic inflammatory demyelinating polyneuropathy (CIDP). As the largest CIDP trial to date with 322 patients across 146 sites, it marked the first major study of a targeted biologic therapy in CIDP. The trial featured a unique two-stage design: An open-label response phase followed by a randomized controlled phase for responders. Dr. Allen explains the rationale behind targeting IgG in CIDP, despite its less clear antibody-mediated mechanism compared to myasthenia gravis. The study demonstrated a 66-70% response rate in the open-label phase, with significantly lower relapse rates compared to placebo in the randomized phase. This research represents a significant advancement in CIDP treatment options, offering a weekly subcutaneous administration that could reduce treatment burden compared to traditional therapies.
In this AANEM podcast, Dr. Andrés De León interviews neuromuscular pathology experts Dr. Aziz Shaibani and Dr. Marcus Pinto about the current state and value of muscle and nerve biopsies in clinical practice. The discussion covers essential topics including proper indications for biopsies, technical considerations in choosing biopsy sites, staining techniques, and the impact of advancing genetic testing on diagnostic approaches. Dr. Shaibani emphasizes that while genetic testing has reduced some muscle biopsy indications, biopsies remain crucial for certain conditions like inflammatory myopathies and mitochondrial disorders. Dr. Pinto details specific scenarios where nerve biopsies are invaluable, particularly in diagnosing vasculitic neuropathy and amyloidosis. Both experts share insights on the complementary role of muscle and nerve biopsies in conditions like systemic vasculitis and discuss how modern diagnostic tools like myositis antibody testing and genetic panels are changing but not eliminating the need for tissue diagnosis.
In this AANEM podcast, Carrie Ford, a CNCT and R.NCS.T. from the University of Utah's Jack Petajan EMG Lab, interviews Dr. Kyle Mahoney, an associate professor at the University of Utah, who provides a comprehensive explanation of neuromuscular junction transmission and the critical concept of the "safety factor." He breaks down complex neurophysiological concepts using accessible analogies, explaining how the safety factor serves as a built-in buffer that ensures reliable nerve-to-muscle signal transmission. The discussion covers normal neuromuscular junction function, the impact of various pathological conditions such as Lambert-Eaton Myasthenic Syndrome, myasthenia gravis, and ALS on neuromuscular transmission, and the clinical significance of repetitive nerve stimulation testing. Dr. Mahoney's clear explanations make these technically challenging concepts more approachable for healthcare professionals, particularly EMG technicians who may be less familiar with the underlying mechanisms of neuromuscular transmission.
Sit back and reminisce about the old oral EMG board examination as two former examiners discuss their thought process on an interesting case. See if Dr. Chiodo passes his Lessons From the Lab examination (he does with flying colors!). You are sure to learn good, practical knowledge when you listen to this episode.
In this AANEM podcast, Dr. Kelly Gwathmey interviews Dr. Aziz Shaibani and Dr. Yessar Hussain, two experienced neuromuscular specialists who run successful private practice clinical research programs in Texas. They discuss the motivations for conducting clinical trials, including expanding treatment options for patients and contributing to medical advancement. The experts share valuable insights about building research infrastructure, recruiting patients, managing competing trials, and balancing clinical duties with research responsibilities. They emphasize the importance of having well-trained research coordinators, efficient databases, and proper facility space. Both physicians stress the need for more clinical trial training in medical education and encourage young physicians to enter the field, noting that while only 5% of physicians participate in clinical trials, there are over 200,000 trials currently listed in the USA, presenting significant opportunities for new researchers.
Join in to this episode of Lessons From the Lab as Drs. Rubin and Hobson-Webb discuss a challenging case filled with many things to ponder. Is the arm finding related to the neuropathy? Are the findings indicative of demyelination? Is there conduction block? Is Dr. Rubin good at ultrasound scanning? You will be sure to learn quite a bit during this discussion!
In this comprehensive discussion, four prominent neuromuscular experts—Drs. Bhaskar Roy, Jeff Allen, Diana Castro, and Luis Querol—explore recent developments in Chronic Inflammatory Demyelinating Polyneuropathy (CIDP). The conversation centers on the new European Academy of Neurology and Peripheral Nerve Society guidelines, highlighting significant changes in diagnostic criteria and disease classification. The experts discuss the challenges of diagnosing CIDP, particularly in pediatric cases and variant forms, while emphasizing the importance of proper electrodiagnostic testing and the role of supportive criteria like CSF studies and MRI. They delve into the emerging field of autoimmune neuropathies and the significance of specific antibody testing. The podcast concludes with a discussion of treatment options, including traditional approaches (IVIG, corticosteroids, plasmapheresis) and newer therapies such as FcRn inhibitors and complement-targeting drugs, while also addressing the controversial role of rituximab in CIDP treatment. Throughout the discussion, the experts stress the importance of regular diagnostic reassessment and the need for more personalized treatment approaches based on patient profiles.
This podcast discusses paraproteinemic neuropathies, featuring experts Dr. Michelle Maruman and Dr. Eli Naddaf. They explore the definition and clinical significance of monoclonal proteins, the necessary tests for diagnosing these conditions, and the various types of paraproteinemic neuropathies. The discussion covers IgM-associated neuropathies, including DADS, CANOMAD, and Waldenstrom's acroglobulinemia-associated neuropathies, as well as non-IgM neuropathies such as POEMS syndrome and light chain amyloidosis. The experts detail the clinical features, diagnostic criteria, and management approaches for these conditions, emphasizing the importance of accurate diagnosis and appropriate treatment. They conclude by reminding clinicians that the co-occurrence of peripheral neuropathy and monoclonal gammopathy in aging populations is often coincidental, and a careful evaluation is necessary to establish a causal relationship.
Despite its recognition for nearly 40 years, anti-MAG neuropathy continues to have limited therapeutic options. The emergence of bruton tyrosine kinase inhibition as a new therapeutic pathway appears promising. In this interview, Dr. Amro Stino interviews Dr. Chiara Briani on her 2023 paper exploring the prevalence of the MYD 88 mutation among patients with anti-MAG neuropathy. This is discussed within the broader context of disease presentation, current treatment landscape, and future drug development.
Dr. Andrés De León interviews Drs. Simon Podnar and Gregor Omejec about their research on recovery of ulnar nerve conduction block at the elbow.
Dr. Chilvana Patel interviews Dr. Khadilkar on the article titled "Acquired Hyperexcitable Peripheral Nerve Disorders: Clinical and Laboratory Features, Therapeutic Responses, and Long-Term Follow-Up." This study examines the clinical and laboratory characteristics of acquired hyperexcitable peripheral nerve disorders, evaluates therapeutic responses, and provides insights from long-term follow-up observations.
Did you miss Lessons From the Lab LIVE 2? Watch the recording now and see the fun you missed as Drs. Devon Rubin and Christopher Lamb present and discuss a unique case of a young rock climber with arm weakness.
Carrie Ford, CNCT, RNSCT, REPT (Emeritus) interviews Peter Grant, MD who is a fraud and abuse expert for the FBI Office of Inspector General, US Attorney’s Office, private insurers, and state medical boards. During this podcast, Peter discusses AANEM lab accreditation—how and when it got started. Dr. Grant explains how to apply for lab accreditation, the benefits of being an accredited lab, exemplary accreditation status vs regular accreditation, and how the HB2639 will affect lab accreditation.
Carrie Ford, CNCT, RNSCT, REPT (Emeritus) interviews Peter Grant, MD who is a fraud and abuse expert for the FBI, Office of Inspector General, US Attorney’s Office, private insurers, and state medical boards. In this podcast Dr. Grant discusses promoting quality electrodiagnostic medicine through legislation—HB2639 explaining the history and need for this legislation, as well as explaining EDX “fraudsters,” and roadblocks that have occurred with this legislation. Dr. Grant also discusses the AANEM’s state liaisons, lobbying in Washington, DC, and meetings with congressman Pete Sessions for support of HB2639.
Join this Lessons From the Lab as Dr. Devon Rubin picks the amazing brains of Drs. Donald Sanders and Janice Massey on the approach to a patient with weakness. Learn what it means when a patient walks into the office sucking on hard candy as well as what tools should be used to think about and assess for an uncommon neuromuscular disorder.
Carrie Ford, CNCT, RNSCT, REPT (Emeritus), interviews Peter Grant, MD, for a podcast on electrodiagnostic (EDX) fraud and abuse. Dr. Grant is a fraud and abuse expert for the FBI, Office of Inspector General, US Attorney’s Office, private insurers, and state medical boards. In this podcast, Dr. Grant explains EDX fraud and how it adversely affects PM&R and neurology, which includes hand-held devices, billing unnecessary repeat studies, billing unnecessary multiple nerves with EMG, and mobile diagnostic labs.
Dr. Nadia Khalil interviews Dr. Collin Grant on his experience in private practice. He shares his take on the highlights, challenges, and keys for success.
Have you ever encountered a patient with progressive patchy weakness in various muscles throughout the body? Have you ever performed an EMG in which the findings don’t always fit perfectly into what you were expecting? Have you ever wondered whether you even need to perform an EMG in a patient with weakness? Have you ever wondered how much fun it would be to listen to a new episode of Lessons From the Lab? Well, you have come to the right place to find some answers to these questions! Join Drs. Rubin and Narayanaswami as they ponder and discuss many clinical, electrodiagnostic, and practical approaches to an interesting patient with progressive weakness.
Dr. Nadia Khalil interviews Dr. Ileana Howard and Dr. Kelly Gwathmey on their careers in neuromuscular medicine. They define a neuromuscular practice and highlight how meaningful, challenging, and exciting this field of medicine is.
Dr. Nadia Khalil interviews Dr. Nicholas Johnson on a career in research. He describes what research in practice looks like, his inspiration, and pearls for success.
Dr. Nadia Khalil interviews Dr. Milind Kothari and Dr. Sandra Hearn on academic practice. They define what life as a clinician educator looks like and share pearls from their own journeys for success.
If you had to evaluate a patient with hand numbness on a deserted island and could only take one EDX item with you, what would it be? Tune in to this episode to see what Drs. Devon Rubin and Michael Cartwright would choose! And learn many more tips of the trade as they discuss a common yet sometimes complicated problem in the EMG laboratory.
Dr. Kelly Gwathmey interviews Dr. Juerd Wijntjes on the article titled "Comparison of muscle ultrasound and needle electromyography findings in neuromuscular disorders." This study explores the correlation of needle electromyography changes with both visual and quantitative muscle ultrasound results in patients with neurogenic and myopathic disorders.
Drs. Mohamed Taha and John Morren speak with Andy Galbreath about their recent Muscle & Nerve paper on Artificial Intelligence in NM and EDX Medicine. The authors discuss concepts of machine learning, deep learning, and artificial neural networks as they relate to NM and EDX medicine. Limitations and regulatory challenges are also discussed. Muscle & Nerve. 2024;69:260-272.
Dr. Devon Rubin challenges the father-son combination of Drs. Peter Dyck and Jim Dyck with a case of peripheral neuropathy. Watch to find out whether the patient’s diabetes was the culprit or whether there was another cause. You will not be disappointed as you learn many pearls in the clinical and EDX evaluation of peripheral neuropathy. Visit our website for more information and educational materials education.aanem.org.
Did you miss the first-ever Lessons From the Lab LIVE? Listen and watch what fun you missed now! Hear Devon Rubin, MD, and Ruple Laughlin, MD, as they discuss a case on unilateral leg numbness.
This podcast is a discussion of three challenging electrodiagnostic cases. Teresa Spiegelberg, CNCT interviews three neuromuscular and electrodiagnostic experts: Dr. Ann Little, MD, Dr. Gary Gallagher, MD, and Dr. James Leonard, Jr. MD.
The first case explores the challenges of routine electrodiagnostic testing in someone with a chronic, underlying brachial plexopathy. The second case discusses the expected electrophysiological changes in a patient with a presynaptic neuromuscular junction disorder. In the third case, electrophysiological features of a patient with Hirayama's Disease (i.e. monomelic amyotrophy) are discussed.
Listen to this episode to see if Dr. Grant thinks that Dr. Rubin appropriately evaluated a patient with suspected polyneuropathy – is one NCS too few, are 22 NCS too many? Tune in to find out the answer, and much more!
Dr. Devon Rubin presents Dr. David Preston with a challenging case of a man with subacute lower extremity weakness. Enjoy the potpourri of information about anticoagulation, A waves, F waves, demyelination, ultrasound, Siri, and so much more! Visit our website for more information and educational materials education.aanem.org.
This episode of Lessons From the Lab should make you laugh, think, and maybe cry as Drs. Devon Rubin and Dianna Quan discuss various approaches to the evaluation of patients with suspected motor neuron disease. Visit our website for more information and educational materials education.aanem.org.
Chilvana Patel, Associate Professor and Neurology Residency Program Director at University of Texas Medical Branch Galveston, Texas, interviewing Dr. Bhai who is an Assistant Professor in the Department of Neurology at UT Southwestern Medical Center and the Director of the Neuromuscular Center in the Institute of Exercise and Environmental Medicine at Texas Health Presbyterian Hospital Dallas and Dr. Vissing who is a professor in Department of Neurology at university of Copenhagen, Denmark and Director of Copenhagen Neuromuscular Center at the National Hospital about their recently published articles in Muscle and Nerve in April 2023 on Diagnosis and management of metabolic myopathies.
Dr. Rothman interviews Drs. Stratton and Yang to discuss the treatment landscape of Duchenne Muscular Dystrophy, highlighting Elevidys, the newly approved recombinant gene therapy.
Join us in this episode as Devon Rubin, MD, challenges Professor Erik Stalberg with an unknown case and discusses various EMG approaches to a patient with suspected neuromuscular junction disease. Watch Professor Stalberg grade Dr. Rubin’s single fiber pairs and hearing about single fiber EMG on dogs will surely make you smile!
Hear from Andrew D. Galbreath, DO, as he meets with Ileana Howard, MD, to discuss her recent paper: Respiratory Considerations in Patients With Neuromuscular Disorders.
In Episode 6 of Lessons From the Lab, we have a fun, educational discussion with Dr. Robert Irwin, current president of AANEM, about an interesting patient with scapular winging. Learn about clinical, electrodiagnostic, and neuromuscular ultrasound assessment of scapular winging, and approaches to managing these patients. Visit our website for more information and educational materials education.aanem.org.
Elie Naddaf, MD, meets with Nicholas Maragakis, MD to discuss the ALS treatment landscape.
Devon Rubin, MD, is joined by John Kincaid, MD, to discuss which is the most important tool in the neurologist's bag, the largest wad of cotton, and interesting findings in a patient with foot numbness.Visit our website for more information and educational materials education.aanem.org.
Devon Rubin, MD, is joined by Andrea Boon MD, to discuss EDX and NMUS approaches, intricacies, and difficulties of a patient who presented with respiratory weakness. Visit our website for more information and educational materials education.aanem.org.
Dr. Amro Stino interviews Dr. Larry Robinson about the role of electrodiagnosis in nerve transfers for focal neuropathies and brachial plexopathies.
Dr. Amro Stino interviews Dr. Larry Robinson about the role of electrodiagnosis in nerve transfers for focal neuropathies and brachial plexopathies.
Devon Rubin, MD, is joined by Holli Horak, MD, to discuss the topic: How do we approach suspected ulnar neuropathy in the EMG laboratory?
Dr. Chilvana Patel interviews Dr. Jeffrey Allen about the diagnosis and treatment of chronic inflammatory demyelinating polyneuropathy (CIDP).
Devon Rubin, MD, is joined by Michael Andary, MD, for a lively debate and discussion on EDX approach to radiculopathy. Visit our website for more information and educational materials education.aanem.org.
Devon Rubin, MD, leads an educational, informative, and humorous discussion with Dr. Litchy and Dr. Robinson, on their electrodiagnostic approaches to a patient with symptoms of possible mild carpal tunnel syndrome.
Dr. Elie Naddaf, MD interviews Dr. James Howard, MD about the use of complement and the neonatal Fc receptor inhibitors in myasthenia gravis, highlighting CHAMPION MG (ravulizumab) and ADAPT (efgartigimod) trials.
Elie Naddaf, MD, interviews James Howard, MD, about the use of complement and the neonatal Fc receptor inhibitors in myasthenia gravis (MG), highlighting CHAMPION MG (ravulizumab) and ADAPT (efgartigimod) trials.
Dr. Chilvana Patel interviews Dr. Faye Chiou Tan on Musculoskeletal Mimics of Cervical Radiculopathy
Dr. Chilvana Patel interviews Dr. Faye Chiou Tan on musculoskeletal mimics of cervical radiculopathy.
Dr. Beecher interviews Drs. Nassim Rad and Crystal Yeo on Spinal Muscular Atrophy (SMA) and its Management
Dr. Beecher interviews Drs. Nassim Rad and Crystal Yeo on Spinal Muscular Atrophy (SMA) and its Management.
Dr. Naddaf interviews Dr. Vucic on Diagnostic Utility of Gold Coast Criteria in Amyotrophic Lateral Sclerosis
Dr. Naddaf interviews Dr. Vucic on diagnostic utility of gold coast criteria in amyotrophic lateral sclerosis (ALS).
Dr. Hearn interviews Dr. Van Den Bergh on European Academy of Neurology/Peripheral Nerve Society Guideline on Diagnosis and Treatment of Chronic Inflammatory Demyelinating Polyradiculoneuropathy: Report of a Joint Task Force—Second Revision. References: https://pubmed.ncbi.nlm.nih.gov/34327760/ and https://pubmed.ncbi.nlm.nih.gov/34085743/
Dr. Hearn interviews Dr. Van Den Bergh on European Academy of Neurology/Peripheral Nerve Society Guideline on diagnosis and treatment of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP): Report of a joint task force.
References: https://pubmed.ncbi.nlm.nih.gov/34327760/ and https://pubmed.ncbi.nlm.nih.gov/34085743/
Dr. Chilvana Patel, MD interviews Dr. Jeffrey Allen, MD about the diagnosis and treatment of chronic inflammatory demyelinating polyneuropathy.
Dr. Patel interviews Dr. Dubey and Dr. Zekeridou on Neuromuscular complications of Immune Checkpoint Inhibitors.
Dr. Patel interviews Drs. Dubey and Zekeridou on neuromuscular complications of immune checkpoint inhibitors.
Dr. Katarzyna Ibanez interviews Dr. Timothy Dillingham on Evaluation of Persons With Suspected Lumbosacral and Cervical Radiculopathy.
Dr. Katarzyna Ibanez interviews Dr. Timothy Dillingham on evaluation of persons with suspected lumbosacral and cervical radiculopathy.
Dr. Elahi Behzad interviews Dr. Michael H. Rivner on the clinical features of LRP4/agrin-antibody–positive Myasthenia Gravis.
Dr. Elahi Behzad interviews Dr. Michael H. Rivner on the clinical features of LRP4/agrin-antibody positive Myasthenia Gravis (MG).
Dr. Elie Naddaf interviews Dr. Amanda Guidon and Dr. Anthony Amato regarding coronavirus 19 (COVID19) and Neuromuscular disorders. This podcaste reviews the potential neuromuscular complications of COVID-19, impact of COVID-19 on patients with preexisting neuromuscular disease, and guidance for management of immunosuppressive and immunomodulatory therapies and timing vaccination. We also review the impact of COVID19 on training in neuromuscular and electrodiagnostic medicine.
Dr. Elie Naddaf interviews Dr. Georgia Malandraki and Dr. Kendrea Garand on the approach to dysphagia, with focus on neuromuscular disorders.
Dr. Elie Naddaf interviews Drs. Georgia Malandraki and Kendrea Garand on the approach to dysphagia, with focus on neuromuscular disorders.
Dr. Priya Dhawan interviews Drs. Mohamed Kazamel and Robert Desnick on their article, Porphyric Neuropathy Part II.
Dr. Priya Dhawan interviews Drs. Mohamed Kazamel and Robert Desnick on their article, Porphyric Neuropathy Part I.
Dr. Priya Dhawan interviews Drs. Mohamed Kazamel and Robert Desnick on their article, Porphyric Neuropathy Part II.
Dr. Priya Dhawan interviews Drs. Mohamed Kazamel and Robert Desnick on their article, Porphyric Neuropathy Part I.
Dr. Willer interviews Dr. Caress on his article, COVID-19-Associated Guillain-Barre Syndrome: The Early Pandemic Experience. Please review these papers that were mentioned in this podcast:
"Epidemiological and cohort study finds no association between COVID-19 and Guillain-Barre syndrome" "COVID-19 vaccine and Guillain-Barre ́syndrome: let's not leap to associations"
Dr. Willer interviews Dr. Caress on his article, COVID-19-associated Guillain-Barre syndrome: The early pandemic experience.
Please review these papers that were mentioned in this podcast:
Dr. Patel interviews Dr. Stino on his article, Autonomic Neuropathies.
Dr. Patel interviews Dr. Stino on his article, Autonomic Neuropathies.
Dr. Waheed interviews Dr. LoRusso and Dr. Statland on thier article, Guidelines on clinical presentation and management of nondystrophic myotonias.
Dr. Waheed interviews Drs. LoRusso and Statland on their article, Guidelines on clinical presentation and management of nondystrophic myotonias.
Dr. Elie Naddaf interviews Drs. Amanda Guidon and Anthony Amato regarding COVID-19 and neuromuscular disorders. This podcast reviews the potential neuromuscular complications of COVID-19, impact of COVID-19 on patients with preexisting neuromuscular disease, and guidance for management of immunosuppressive and immunomodulatory therapies and timing vaccination. We also review the impact of COVID-19 on training in neuromuscular and electrodiagnostic medicine.
Dr. Elie Naddaf interviews Dr. Andrea Boon about the approach to patients presenting to the EMG laboratory with respiratory symptoms, to evaluate for underlying neuromuscular cause of these symptoms. Dr Boon describes the role of phrenic nerve conduction studies and needle electromyography of the diaphragm and the technical limitations of these studies. Dr Boon also details the role of diaphragm ultrasound to enhance the accuracy and safety of diaphragm electromyography, and improve the diagnostic yield of EDX testing, including an overview of the diaphragm ultrasound technique
Dr. Sandra Hearn interviews Dr. Dr. Darryl Sneag, Dr. Danielle Stoner, Dr. Scott Wolfe, Dr. Joseph Feinberg, Anterior interosseous nerve syndrome.
Dr. Ibanez interviewing Dr. Elliott on “Rehabilitative approach to ALS patients” while also highlighting his article “Eye-controlled, power wheelchair performs well for ALS patients.
Dr. Justin Willer interviews Dr. Constantine Farmakidis on his article, Immunomodulatory and Immunosuppressive Therapy for Neuromuscular Disorders Part II.
Dr. Justin Willer interviews Dr. Constantine Farmakidis on his article, Immunomodulatory and Immunosuppressive Therapy for Neuromuscular Disorders Part I.
Dr. Priya Dhawan interviews Dr. Kelly Gwathmey on her article, Nutritional Neuropathies.
Dr. Elie Naddaf interviews Dr. Andrea Leep Hunderfund on her article, Quality Improvement Projects in the EMG laboratory.
Dr. Elahi Behzad interviews Dr. Srikanth Muppidi on his article, Long-term Safety and Efficacy of Eculizumab in Generalized Myasthenia Gravis.
Dr. Sandra Hearn interviews Dr. John Norbury on his article, Ultrasound-Guided Treatment of Peripheral Entrapment Neuropathies.
Dr. Elie Naddaf interviews Lawrence R. Robinson MD on his article, Effect of shoulder and elbow position on ulnar nerve conduction.
Dr. Justin Willer interviews Dr. Michael Hehir on his article, Thymectomy may not be associated with clinical improvement in MuSK myasthenia gravis.
Dr. Elie Naddaf interviews Dr. Mazen Dimachkie on his article, Satisfactory Response With Achieving Maintenance Low-Dose Prednisone in Generalized Myasthenia Gravis. To estimate the satisfactory response rate (SR%) with achieving maintenance, low-dose prednisone in acetylcholine receptor antibody-positive generalized myasthenia gravis. In this retrospective study, we estimate the SR% as defined by (remission/minimal manifestations status for at least 6 months using 7.5 mg or less of prednisone daily, for maintenance treatment at 2, 4, and 6 years after symptoms onset) for patients who were not taking steroid-sparing immunosuppressant (SSI) as a primary outcome and for patients taking an SSI as a secondary outcome. Forty-five patients were not taking an SSI at 2 years, 34 patients at 4 years, and 17 patients at 6 years; SR% was 44.4%, 64.7%, and 58.8%, respectively. Thirty-six patients were taking an SSI at 2 years, 22 patients at 4 years, and 15 patients at 6 years; the SR% was 50.0%, 45.4%, and 66.7%, respectively. Nearly half of the generalized myasthenia gravis patients who were not taking an SSI achieved an SR.
Dr. Justin Willer interviews Dr. Yuebing Li about his article, Clinical and Electrodiagnostic Features Of Nontraumatic Sciatic Neuropathy. This study sought to characterize etiologies and features of sciatic neuropathy unrelated to penetrating nerve trauma. Methods: This investigation was a retrospective review of 109 patients with electrodiagnostically confirmed sciatic neuropathies. Results: Hip replacement surgery represented the most common (34.9%) etiology, whereas inflammatory sciatic neuropathy was seen in 7.3%. Electrodiagnostic testing revealed an axonal neuropathy in 95.4% and a demyelinating neuropathy in 4.6%. Predominant involvement of the peroneal division was seen in 39.4% and was tibial in 5.5%. Nine of 31 (29.0%) patients who had MRI or neuromuscular ultrasound study showed abnormalities within the sciatic nerve. At the final visit, 46.4% of patients required assistance for ambulation. Young age, lack of severe initial weakness, and presence of tibial compound muscle action potential or sural sensory nerve action potential were predictors of favorable outcome. Discussion: Sciatic neuropathies are usually axonal on electrodiagnostic testing, affect preferentially the peroneal division, and are commonly associated with incomplete recovery. Muscle Nerve 59:309–314, 2019.
Dr. Behzad Elahi interviews Dr. Devin I. Rubin on his article, Needle Electromyography and Histopathologic Correlation in Myopathies. Fibrillation potentials and short-duration MUPs predict pathologic changes of muscle fiber necrosis, splitting, and/or vacuolar changes (as seen with inflammatory myopathies and muscular dystrophies). Absence of fibrillation potentials suggests other myopathologic changes (e.g., congenital myopathy). Muscle Nerve 59:315-320, 2019.
Dr. Scott Speelziek interviews Dr. Elie Naddaf on his article, Muscle Biopsy EMG Correlation. In myopathies, the correlation of individual electromyographic and histopathologic findings remains poorly explored, as most previous studies have focused on the ability of muscle biopsy and electromyography to distinguish the neuropathic vs. myopathic nature of the underlying neuromuscular disease. By demonstrating a clear correlation of various electromyographic and histopathologic findings, this study improves interpreting electrodiagnostic testing in myopathies, and serves as the basis to further assess the correlation between clinical, electromyographic, and histopathologic findings.
Dr. Justin Willer interviews Dr. Athar Parveen on her article, Long‐term neuromuscular outcomes of west nile virus infection A clinical and electromyographic evaluation of patients with a history of infection. The study found that 33% of these patients (10 of 30) showed abnormalities on either nerve conduction or needle electromyography due to primary or secondary outcomes of WNV infection. Most common electrodiagnostic findings and causes of long-term disability were related to anterior horn cell poliomyelitis (WNV poliomyelitis). Electrical data on these patient populations were similar to those observed in chronic poliomyelitis. With more than 16,000 cases of WNV neuroinvasive disease reported across the USA since 1999, understanding clinical outcomes from infection will provide a resource for physicians managing long-term care of these patients. Muscle Nerve 57: 77-82, 2018.
Dr. Justin Willer interviews Dr. Jeffrey Allen on his article, Electrodiagnostic Errors Contribute to Chronic Inflammatory Demyelinating Polyneuropathy Misdiagnosis.
Dr. Ted Burns interviews Dr. William Litchy and Drs. Jim and Peter Dyck on their articles, Amyloid TTR treatment studies. The articles are Inotersen Treatment for Patients with Hereditary Transthyretin Amyloidosis (N Engl J Med. 2018 Jul 5;379(1):22-31. doi: 10.1056/NEJMoa1716793) and Patisiran, an RNAi Therapeutic, for Hereditary Transthyretin Amyloidosis (N Engl J Med. 2018 Jul 5;379(1):11-21. doi: 10.1056/NEJMoa1716153.)
Dr. Speelziek interviews Dr. Kurt Kimpinski and Dr. Luciano Sposato on their article, Subcutaneous versus intravenous immunoglobulin for chronic autoimmune neuropathies. A meta-analysis. High-dose intravenous immunoglobulin (IVIg) is an evidence-based treatment for multifocal motor neuropathy (MMN) and chronic inflammatory demyelinating polyneuropathy (CIDP). Recently, subcutaneous immunoglobulin (SC-Ig) has received increasing attention. The authors performed a meta-analysis of reports of efficacy and safety of SC-Ig versus IVIg for inflammatory demyelinating polyneuropathies.The efficacy of SC-Ig is similar to IVIg for CIDP and MMN and has a significant safety profile. Muscle Nerve 55: 802-809, 2017.
Dr. Sandra Hearn interviews Dr. James Richardson on his article, Complex and simple clinical reaction times are associated with gait, balance, and major fall injury in older subjects with diabetic peripheral neuropathy. In the diabetic peripheral neuropathy subjects, the ratio of complex RTclin accuracy to simple RTclin latency was strongly associated with longer UST, and decreased step width variability and range on an uneven surface. Additionally, the 2 DPN subjects sustaining major injuries had lower complex RTclin accuracy:simple RTclin latency than those without.The ratio of complex RTclin accuracy:simple RTclin latency is a potent predictor of UST and frontal plane gaitvariability in response to perturbations and may predict major fall injury in older subjects with DPN. These short latency neurocognitive measures may compensate for lower limb neuromuscular impairments and provide a more comprehensive understanding of balance and fall risk. Am J Phys Med Rehabil. 2017 Jan;96(1):8-16.
Dr. Willer interviews Dr. Johanna Hamel and Dr. Eric Logigian about their article Acute Nutritional Axonal Neuropathy. This study describes clinical, laboratory, and electrodiagnostic features of a severe acute axonal polyneuropathy common to patients with acute nutritional deficiency in the setting of alcoholism, bariatric surgery (BS), or anorexia. Thirteen patients were identified with a severe, painful, sensory or sensorimotor axonal polyneuropathy that developed over 2-12 weeks with sensory ataxia, areflexia, variable muscle weakness, poor nutritional status, and weight loss, often with prolonged vomiting and normal cerebrospinal fluid protein. Vitamin B6 was low in half and thiamine was low in all patients when obtained before supplementation. Patients improved with weight gain and vitamin supplementation, with motor greater than sensory recovery. The authors suggest that acute or subacute axonal neuropathy in patients with weight loss or vomiting associated with alcohol abuse, BS, or dietary deficiency is one syndrome, caused by micronutrient deficiencies. Muscle Nerve 57: 33-39, 2018.
Dr. Scott Speelziek interviews Dr. Pushpa Narayanaswami and Dr. Lyell K Jones about the article, The Value Transformation of Heath Care: Impact on Neuromuscular and Electrodiagnostic Medicine. Beginning in 2017, most physicians who participate in Medicare are subject to the Medicare Access and CHIP Reauthorization Act (MACRA), the milestone legislation that signals the US health care system's transition from volume-based to value-based care. Here we review emerging trends in development of value-based healthcare systems in the US. MACRA and the resulting Quality Payment Program create 2 participation pathways, the Merit-based Incentive Payment System (MIPS) and the Advanced Alternative Payment Model (AAPM) pathway. Although there are several program incentives for AAPM participation, to date there have been few AAPM options for specialists. MIPS and its widening bonus and penalty window will likely be the primary participation pathway in the early years of the program. Value-based payment has the potential to reshape health care delivery in the United States, with implications for neuromuscular and electrodiagnostic (EDX) specialists. Meaningful quality measures are required for neuromuscular and EDX specialists. Muscle Nerve 56: 679-683, 2017.
Dr. Ted Burns interviews Dr. Elie Naddaf and Dr. Margherita Milone about the article Hereditary Myopathies With Early Respiratory Insufficiency in Adults. Hereditary myopathies with early respiratory insufficiency as a predominant feature of the clinical phenotype are uncommon and underestimated in adults. The authors highlighted the most common hereditary myopathies associated with early respiratory insufficiency as the predominant clinical feature, and underscored the importance of a timely diagnosis for patient care. Muscle Nerve 56: 881-886, 2017.
Evaluation of Patients With Refractory Chronic Inflammatory Demyelinating Polyneuropathy
International Consensus Guidance for Management of Myasthenia Gravis: Executive Summary
Optimizing Muscle Selection for Electromyography in Amyotrophic Lateral Sclerosis
Association of Inclusion Body Myositis With T Cell Large Granular Lymphocytic Leukaemia
Transthyretin Amyloid Neuropathy has Earlier Neural Involvement but Better Prognosis than Primary
Gene Editing in Monogenic Diseases With CRISPR by Eric Olson, PhD
Presymptomatic ALS Genetic Counseling and Testing: Experience and Recommendations
Randomized Trial of Thymectomy in Myasthenia Gravis by Dr. Gil Wolfe
Dr. Ted Burns interviews Dr. Timothy Dillingham about the Normative Data Taskforce (NDTF) report on establishing high quality reference values for nerve conduction studies (NCS). Because there are not uniform standards for NCS in the United States, the NDTF developed consensus-based methodological criteria for examining NCS and applied this quality criteria to a systematic review of the published literature. The NDTF has done the difficult work of scouring the literature and identifying high quality articles for our members. Nerve conduction testing techniques and normative reference values from these studies that met a high quality standard are now presented for our membership to use in an easy to follow tabular format. Two reports on the work of the NDTF were published in the September issue of Muscle and Nerve: Muscle Nerve. 2016 Sep;54(3):366-70. doi: 10.1002/mus.25204 and Muscle Nerve. 2016 Sep;54(3):371-7.
Rapid Screening for Inflammatory Neuropathies by Standardized Clinical Criteria
Dr. Justin Willer interviews Dr. Kelly Gwathmey about her article, Sensory Neuronopathies. The sensory neuronopathies (or ganglionopathies) are a small subcategory of neuropathies characterized by primary degeneration of the dorsal root ganglia and trigeminal ganglion sensory neurons, resulting in a distinctive clinical presentation. Patients typically have subacute onset of asymmetric, non–length-dependent sensory impairment and early ataxia. The etiologies of acquired sensory neuronopathies are rather limited. Early identification is imperative, as they may herald an underlying malignancy or an autoimmune condition such as Sjögren syndrome. This podcast reviews the Muscle and Nerve article on this subject. Muscle Nerve 53: 8–19, 2016.
Mutations in SEPT9 Cause Heredic Neuralgic Amyotrophy by Phillip Chance, MD and Mark Hannibal, MD
Dr. Stephen Goutman interviews Drs. Pushpa Narayanaswami and Seward Rutkove about their article Critically re-evaluating a common technique: Accuracy, reliability, and confirmation bias of EMG. This study supports that in evaluations of radiculopathy (1) serial EMG studies should be performed by the same electromyographer since intrarater reliability is better than interrater reliability; (2) knowledge of clinical information does not bias EMG interpretation substantially, (3) EMG has moderate diagnostic accuracy for radiculopathy with modest specificity and electromyographers should exercise caution interpreting mild abnormalities. Neurology. 2016 Jan 19:86(3):218-23.
Dr. Justin Willer interviews Dr. Lisa Hobson Webb about her Muscle and Nerve article on safely tapering mycophenolate mofetil in myasthenia gravis patients. MMF is frequently used to treat patients with MG but there is little information to guide clinicians on the safety of reducing the dose in well-controlled patients. Discussion includes standard dosages, determining clinical response to MMF and suggested goals in tapering MMF. Muscle Nerve. 2015 Aug;52:211-5. doi: 10.1002 mus.24694. Epub 2015 Jun 18.
In this second part of the Clinical Presentation and Acquired Causes of Rhabdomyolysis podcast, Dr. Ted Burns interviews Drs. Jessica Nance and Andrew Mammen about their paper Diagnostic evaluation of rhabdomyolysis from the June 2015 issue of Muscle and Nerve. Rhabdomyolysis is characterized by severe acute muscle injury resulting in muscle pain, weakness, and/or swelling with release of myofiber contents into the bloodstream. Symptoms develop over hours to days after an inciting factor and may be associated with dark pigmentation of the urine. This podcast focuses on the inherited etiologies. For the article in Muscle and Nerve refer to Muscle Nerve 51: 793-810, 2015.
Dr. Stephen Goutman interviews Dr. Nadine Attal about the article she coauthored in Lancet Neurology on pharmacotherapy for neuropathic pain in adults. Drs. Goutman and Attal discuss the evidence and limitations supporting each class of medication aimed at the treatment of neuropathic pain and how these recommendations can be incorporated into clinical practice. Lancet Neurol. 2015 Feb;14:162-173.
Dr. Ted Burns interviews Drs. Jessica Nance and Andrew Mammen about their paper Diagnostic evaluation of rhabdomyolysis from the June 2015 issue of Muscle and Nerve. This podcast focuses on the clinical presentation and acquired causes which can include substance abuse, medication or toxic exposures, electrolyte abnormalities, endocrine disturbances, and autoimmune myopathies. For the article in Muscle and Nerve refer to Muscle Nerve 51: 793-810, 2015.
Patterns of Clinical and Electrodiagnostic Abnormalities in Early Amyotrophic Lateral Sclerosis by Drs. Neil Simon and Noah Kolb
Mary E. Franklin, CNCT, R. EEGT. interviews William W. Campbell, MD on NCS technique for ulnar neuropathy
Neuralgic Amyotrophy (Parsonage-Turner): Etiology, Treatment, Natural History by Nens Van Alfen
Neuralgic Amyotrophy (Parsonage-Turner): Presentation & Diagnosis by Nens Van Alfen
Next Generation Sequencing and its Impact on Neuromuscular Medicine by Dr. Daniel MacArthur
ALS Onset is Influenced by the Burden of Rare Variants in Known ALS Genes by Drs. Baloh and Harms
Muscle Intrusion as a Potential Cause of Carpal Tunnel Syndrome by Dr. Michael Cartwright
Dermatomyositis and Autoantibodies by Dr. Andrew L. Mammen. This is part three of a three part series on immune-mediated myopathies and autoantibodies.
Necrotizing Myopathies by Dr. Andrew L. Mammen. This is part one of a three part series on immune-mediated myopathies and autoantibodies.
Antisynthetase syndrome and myositis by Dr. Andrew L. Mammen. This is part one of a three part series on immune-mediated myopathies and autoantibodies.
Pathokinesiology of Duchenne Muscular Dystrophy by Ernest W. Johnson, MD
Clinical Value of Motor Nerve Conduction Velocity Determination by Ernest W. Johnson, MD
The guideline, entitled, Evidence-based Guideline Summary: Diagnosis and Treatment of Limb-Girdle and Distal Dystrophies. A Report of the Guideline Development Subcommittee of the American Academy of Neurology and the Practice Issues Review Panel of the American Association of Neuromuscular and Electrodiagnostic Medicine, was published in the October 13, 2014, online issue of Neurology®, AAN’s medical journal and makes recommendations about treating and managing complications, which may include muscle symptoms, hearth problems, and breathing problems.
This podcast, Electrodiagnosis of ulnar neuropathy at the elbow (Une): a Bayesian approach, is based on an article in Muscle Nerve. 2014 Mar;49(3):337-44. doi: 10.1002/mus.23913.
Myotonic Dystrophy Health Index: Initial Evaluation of a Disease-Specific Outcome Measure
Vasculitic Neuropathies by Drs. Kelly Gwathmey and P. James B. Dyck interviewed by Dr. Ted
Improving Referring Physicians' Understanding of EMG Reports When Qualifying Radiculopathies
Exome sequencing discussion by Michael Shy, MD and Stephan Zuchner, MD, and interviewed by Ted Burns, MD
Spinal muscular atrophy: Development and Implementation of Potential Treatments
Amyotrophic lateral sclerosis and palliative care: Where we are, and the road ahead by Dr. Leslie J. Blackhall, interviewed by Dr. Michael K. Hehir. Patients with amyotrophic lateral sclerosis (ALS) have high symptom burdens, including pain, fatigue, dyspnea, and sialorrhea, and they must make difficult decisions about the use of life-prolonging therapies, such as long-term mechanical ventilation. The impact of ALS is also felt by family caregivers who often struggle to meet the heavy physical, financial, and emotional demands associated with the illness. Expert multidisciplinary care may improve both quality and length of life of patients with ALS. However, although advances have been made in the treatment of some symptoms, others, including pain management, remain poorly studied. Involvement of palliative care specialists as part of the ALS multidisciplinary team is recommended, as we continue to work toward improving the quality of life for patients and their families. Muscle Nerve, 2012. The ideas and opinions expressed are solely those of the specific authors and do not necessarily represent those of AANEM.
Myasthenia Gravis and the use of IVIg and Therapeutic Plasma Exchange by Dr. Vern Juel interviewed by Dr. Elliot Dimberg.
Inherited Neuropathies: Clinical Overview and Update by Drs. Christopher Klein and Michael Shy interviewed by Dr. Laurie Gutmann. Muscle Nerve. 2013 Jan 30. doi: 10.1002/mus.23775
Justic Willer, MD interviews Eric Loggigian, MD on electrodiagnosis of ulnar neuropathy at the elbow (Une): A bayesian approach.
Cytosolic 5'-nucleotidase 1A autoimmunity in sporadic inclusion body myositis by Dr. Steven A. Greenberg interviewed by Dr. Ted Burns. Ann Neurol. 2013 Mar;73(3):408-18. doi: 10.1002/ana.23840.
Diagnostic Ultrasound of the Fibular (Peroneal) Nerve by Drs. Francis Walker and Michael Cartwright interviewed by Dr. Ted Burns.
Diagnostic Ultrasound of the Ulnar Nerve and Ulnar Neuropathy at the Elbow by Drs. Francis Walker and Michael Cartwright interviewed by Dr. Ted Burns.
Diagnostic Ultrasound of the Median Nerve and Median Neuropathy at the Wrist by Drs. Francis Walker and Michael Cartwright interviewed by Dr. Ted Burns.
Paraneoplastic Neuromuscular Disorders by Drs. Lydia Sharp and Steven Vernino
Diabetic cervical radiculoplexus neuropathy: a distinct syndrome expanding the spectrum of diabetic radiculoplexus neuropathies by Drs. P. J. Dyck and R. Massie, interviewed by Dr. Ted Burns. Brain. 2012 Oct;135(Pt 10):3074-88. doi: 10.1093/brain/aws244.
Chronic pain as a manifestation of potassium channel-complex autoimmunity by Dr. Christopher Klein, interviewed by Dr. Ted Burns. Neurology. 2012;79:1136-44. Epub 2012 Aug 15.
An interview with Dr. Kate Busby about diagnosis of the limb-girdle muscular dystrophies. Interviewed by Dr. Elliot Dimberg.
The Role of Exercise in Amyotrophic Lateral Sclerosis by Dr. Amy Chen
An interview with Dr. Mary Reilly about the article The distal hereditary motor neuropathies in J Neurol Neurosurg Psychiatry. 2012 83:6-14. Interviewed by Dr. Ted Burns.
Drs. Ted Burns, Ludwig Gutmann, Jasper Daube, and Devon Rubin discuss myokymic and neuromyotonic discharges.
Drs. Ted Burns and Vera Bril discuss the article Evidence Based Guidelines on Painful Diabetic Neuropathy. Muscle Nerve. 2011;43:910-7.
Drs. Ted Burns and Christopher Spurney discuss the article Cardiomyopathy of Duchenne muscular dystrophy: current understanding and future directions in Muscle Nerve 2011;44:8-19.
Treatment-induced Diabetic Neuropathy: A Reversible Painful Autonomic Neuropathy by Christopher H. Gibbons, MD
Drs Ted Burns and Teepu Siddique discuss the article Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia, Nature. 2011 Aug 21. doi: 10.1038/nature10353
Drs. Ted Burns, Pariwat Thaisetthawatkul, and P. James Dyck discuss the article Good Nutrional Control May Prevent Polyneuropathy After Bariatric Surgery Muscle Nerve. 2010 Nov;42(5):709-14.
An interview by Dr. Ted Burns with Dr. Michael Shy about the article Charcot-Marie-Tooth disease subtypes and genetic testing strategies in Ann Neurol. 2011 Jan;69(1):22-33. doi: 10.1002/ana.22166.
Dr. Ted Burns and John Stewart discuss the evaluation and management of patients with foot drop, peroneal neuropathies, as well as L5 radiculopathies, lumbosacral plexopathies and proximal sciatic neuropathies.
An interview with Drs. Robert Leshner and Paula Clemens about the article A randomized study of alglucosidase alfa in late-onset Pompe's disease in N Engl J Med. 2010 Apr 15;362(15):1396-406.
An interview with Drs. P. James B. Dyck and Nathan Staff about the article Post-surgical Inflammatory Neuropathy in Brain. 2010 Oct;133(10):2866-80. Epub 2010 Sep 15.
Treatment of Chronic Inflammatory Demyelinating Polyneuropathy by P. James B. Dyck, MD and Jennifer A. Tracy, MD
An interview with Dr. Andrew Mammen about A novel autoantibody recognizing 200 and 100 kDa proteins is associated with an immune-mediated necrotizing myopathy, Arthritis Rheum. 2010 May 23.
An interview with Dr. Krista Kuitwaard about Pharmacokinetics of IVIg and outcome in GBS. Annals Neurol 2009;66:597-603.
A Practical Approach to the Metabolic Myopathies; Diagnosis and treatment: Glycogen Storage Myopathy by Mark A. Tarnopolsky, MD, PhD
An interview with Mark A. Tarnopolsky, MD, PhD, about Metabolic myopathies: Update 2009. J Clin Neuromusc Disease 2009;10:97-121. Interviewed by Ted Burns, MD.
An interview with Michael G. Hanna, MD, and Richard J. Barohn, MD, about genetics, pathophysiology, and treatment of nondystrophic myotonias. Interviewed by Ted Burns, MD.
An interview with Michael G. Hanna, MD, and Richard J. Barohn, MD, about nondystrophic myotonias. Interviewed by Ted Burns, MD.
An interview with Ivo N. van Schaik, MD, PhD, about pulsed high-dose dexamethasone versus standard prednisolone treatment for chronic inflammatory demyelinating polyradiculoneuropathy (PREDICT study): a double-blind, randomized, controlled trial. Interviewed by Ted Burns, MD and Robert Pascuzzi, MD.
Influenza Vaccination Safety for Patients with Myasthenia Gravis by Lorne H. Zinman, MD, MSc, and David N. Juurlink, BPhm, MD, PhD
Inclusion Body Myositis by Anthony A. Amato, MD, and Richard J. Barohn, MD
Evaluation and Treatment of the Inflammatory Myopathies by Anthony A. Amato, MD, and Richard J. Barohn, MD
Toxic, Including Statin, Myopathies by Marinos Dalakas, MD
Is There an Increased Risk of GBS Following Influenza Vaccines or Other Vaccines? by Richard AC Hughes, MD
An interview with John D. England, MD, about the practice parameters about distal symmetrical polyneuropathy. Interviewed by Elliot L. Dimberg, MD, and Robert M. Pascuzzi, MD.
An interview with Joshua Burns, PhD, about the paper, Ascorbic acid for Charcot–Marie–Tooth disease type 1A in children: a randomized, double-blind, placebo-controlled, safety and efficacy trial in Lancet Neurol. 2009 Jun;8(6):537-44. Interviewed by Ted Burns, MD.
Abnormal EMG Findings During Muscle Activation by Jasper R. Daube, MD and Devon I Rubin, MD
Abnormal Needle EMG Findings with the Muscle at Rest by Jasper R. Daube, MD and Devon I Rubin, MD
Needle Electromygraphy by Jasper R. Daube, MD and Devon I Rubin, MD
Needlestick Injuries Among Electromyographers by Farrah Mateen, MD
Risk of Hematoma Following Needle EMG Study in Anticoagulated Patients and Patients on Antiplatelet Therapy by Andrea Boon, MD
Stem Cell Replacement Research for ALS by Nick Maragakis, MD
Lessons Learned in Single Fiber EMG by Erik Stalberg, MD, PhD and Donald Sanders, MD
Early Days of Single Fiber EMG by Erik Stalberg, MD, PhD and Donald Sanders, MD
IgG1 Antibodies to Acetylcholine Receptors in ‘Seronegative’ MG by Angela Vincent, MD
Lifetime Course in Myasthenia Gravis by Mikhail Charny, MD and Murali Pagala, MD
Critical Illness Polyneuropathy and Myopathy by Charles Bolton, MD
Identifying Lumbosacral Radiculopathies by Timothy Dillingham, MD, MS
Pathokinesiology of Duchenne Muscular Dystrophy by Ernest W. Johnson, MD
Autosomal-Recessive and X-linked Forms of Hereditary Motor and Sensory Neuropathy in Childhood by Monique Ryan, M Med, BS, FRACP and Robert Ouvrier, MD, BS, BSc
Immunotherapy in Guillain-Barre Syndrome by Richard AC Hughes, MD
The Therapy of Congenital Myasthenic Syndromes by Andrew G. Engel, MD
Safety of Nerve Conduction Studies in Patients with Implanted Cardiac Devices by Michelle Mellion, MD
Chronic Inflammatory Polyradiculoneuropathy by Peter J. Dyck, MD
An Interview with Andrew J. Haig, MD, author of Haig AJ, et al. Electromyographic and magnetic resonance imaging to predict lumbar stenosis, low-back pain, and no back symptoms. J Bone and Joint Suregy 2007;89:358-366. Haig AJ, et al. Spinal stenosis, back pain, or no symptoms at all? A masked study comparing radiologic and electrodiagnostic diagnoses to the clinical impression. Arch Phys Med Rehabil 2006;87:897-903. Haig AJ, et al. The sensitivity and specificity of electrodiagnostic testing for the clinical syndrome of lumbar spinal stenosis. Spine 2005;30:2667-2676.0. Interviewed by Ted Burns, MD and Gregory T. Carter, MD, MS The participants in this Podcast had nothing to disclose.
Accuracy of Repetitive Nerve Stimulation for Diagnosis of Cramp-Fasciculation Syndrome by Taylor B. Harrison, MD and Michael Benatar, MBChB, DPhi
An Unusual Variant of Acute Idiopathic Polyneuritis by C. Miller Fisher, MD
The Influence of the Reference Electrode on CMAP Configuration by John Kincaid, MD
Uremic Neuropathy: Clinical Features and New Pathophysiologic Insights by Matthew Kiernan, MD
Peripheral Neuropathy in Krabbe Disease by Zaeem Siddiqi, MD
Radiculopathy and the Herniated Lumbar Disc by Michael K. Schaufele, MD
Sural Neuropathy: Etiologies and Predisposing Factors by David Stickler, MD and Wayne Massey, MD
Is Exercise Necessary with Repetitive Nerve Stimulation in Evaluating Patients with Suspected Myasthenia Gravis by Devon Rubin, MD
Myelin Protein Zero Mutation His39Pro by Christopher J. Klein, MD
Interferon-Alpha Beta–Mediated Innate Immune Mechanisms in Dermatomyositis by Steven A. Greenberg, MD
Electrophysiological Findings in a Cohort of Old Polio Survivors by Eric J. Sorenson, MD
Clinical Value of Motor Nerve Conduction Velocity Determination by Ernest W. Johnson, MD
An Interview with P. James B. Dyck, MD author of "Diabetic and Nondiabetic Lumbosacral Radiculoplexus Neuropathies: New Insights into Pathophysiology and Treatment." an article appearing in Muscle & Nerve. 2002 Apr;25(4):477-91. Interviewed by Michelle Mauermann, MD and Jeremy Lanford, MD. The participants in this Podcast had nothing to disclose.
Rehabilitation Management of Peripheral Neuropathy by Greg Carter, MD, MS
The Natural History of Primary Lateral Sclerosis by Paul Gordon, MD
An Interview with Rabi Tawil, MD author of "Facioscapulahumeral Muscular Dystrophy" an article appearing in the July 2006 issue of Muscle & Nerve. Interviewed by Ted Burns, MD and Vern Juel, MD.
An Interview with Phillip Chance, MD and Mark Hannibal, MD authors of "Mutations in SEPT9 Cause Heredic Neuralgic Amyotrophy" an article appearing in Volume 30, Number 10, October 2005, Nature Genetics. Interviewed by Ted Burns, MD and Devon Rubin, MD.
Axillary Pain as a Heralding Sign of Neoplasm Involving the Upper Thoracic Root by Devon Rubin, MD
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