Editor-in-Chief Shawn Kennedy and Clinical Editor Betsy Todd present the highlights of the May issue of the American Journal of Nursing. On this month’s cover, nurses and other health care professionals provide care to a patient in distress. The authors of our first CE, “Original Research: Creating an Evidence-Based Progression for Clinical Advancement Programs,” developed eight nursing competency domains and 186 related knowledge, skills, and attitudes for professional nursing practice, then sought to validate them and to determine their developmental progression within a clinical advancement program. Our second CE, “Venous Thromboembolism: Updated Management Guidelines,” presents an overview of venous thromboembolism plus a review of recommendations from an updated guideline related to treatment options, nursing practice, patient education, diagnostic testing, and more. Our next article, “Environments and Health: Project TENDR,” discusses a collaborative initiative of scientists, health professionals, and children’s health advocates to promote chemical policy reform to reduce exposure to hazardous chemicals. In “Wound Wise: Deep Tissue Pressure Injury: A Clinical Review,” the authors describe the assessment, documentation, prevention, and treatment of these injuries. In addition, there’s News, Reflections, Drug Watch, Art of Nursing, and more.