Beyond the Endpoint

Latest Episodes:

Pediatric Dosing: Protecting Children Through Research, Not From It Nov 04, 2026

Show notes

Danny Benjamin, principal investigator of the Pediatric Trials Network, joins Beyond the Endpoint to explain why kids are not small adults, especially when it comes to dosing. He shares how a neonatal intensive care unit conversation grew into a national network, how platform trials changed pediatric research, and what safeguards parents should look for. Learn more and view resources: https://dcri.org/blog/s3-ep-5-pediatric-dosing-protecting-children-through-research-not-it

What's in a Name? The Journey from PCOS to PMOS Oct 21, 2026

Show notes

Anuja Dokras, MD, MHCI, PhD, joins Emily O'Brien and new co-host Daniel Edmonston to explain why PCOS is now PMOS, polyendocrine metabolic ovarian syndrome. She traces the global effort behind the new name and how it could reduce stigma, improve frontline care, and open doors to new research funding. https://dcri.org/blog/s3-ep-4-whats-name-journey-pcos-pmos

Beyond the Headlines: AI, Lp(a), Faster Trials, and the Future of Research Funding Oct 07, 2026

Show notes

Hosts Manesh Patel and Emily O'Brien look past the headlines on Novartis' Lp(a) drug trial results, AI agents in medicine, the FDA's Operation Trailblazer to speed up clinical trials, Dolly Parton's support for COVID research, and the case for steady NIH funding. https://dcri.org/blog/s3-ep-3-beyond-headlines

The Critical Filling: 30 Years with Harrington, Peterson & Curtis Sep 23, 2026

Show notes

Three former DCRI executive directors, Bob Harrington, Eric Peterson, and Lesley Curtis, join Beyond the Endpoint for part two of the institute's 30th anniversary series. They reflect on growth, crisis, inconvenient truths, and the culture they believe will carry DCRI through whatever comes next. https://dcri.org/blog/s3-ep-2-critical-filling-30-years-harrington-peterson-curtis

The Critical Filling: 30 Years with Harrington, Peterson & Curtis Sep 23, 2026

Show notes

The Foundation & the Future: 30 Years with Califf & Hernandez Sep 09, 2026

Show notes

To mark DCRI's 30th anniversary, this first episode in a two-part series features founding director Robert Califf and current Executive Director Adrian Hernandez as they look back at the institute's evolution and ahead to its future. Part two arrives Sept. 23. https://dcri.org/blog/s3-ep-1-foundation-future-30-years-califf-hernandez

Beyond the Headlines: PMDD and Antihistamines, Real-Time FDA Study Monitoring Using Al, and More! May 13, 2026

Show notes

In this Beyond the Headlines episode, we examine the FDA's push for real-time clinical trial data, an executive order making psychedelic research a federal priority, advances in CAR T-cell therapy for autoimmune conditions, and viral claims about antihistamines as a treatment for premenstrual dysphoric disorder. 🔗 Access resources related to this episode: https://dcri.org/blog/s2-ep-16-beyond-headlines

The COPD Gap: Diagnosis, Treatment, and Access Apr 22, 2026

Show notes

COPD is the third leading cause of death worldwide. Yet the disease remains underdiagnosed and underfunded. Host Emily O'Brien and pulmonologist Chris Mosher discuss stigma, funding disparities, barriers to care, and promising research that's bringing new hope to patients. 🔗 Access resources related to this episode: https://dcri.org/blog/s2-ep-15-copd-gap-diagnosis-treatment-and-access

Hard Habits: What Kidney Stones Teach Us About Behavior Change Apr 08, 2026

Show notes

Why is it so hard to change our behavior, even when we know what we should be doing? Host Emily O'Brien sits down with urologist and DCRI faculty member Dr. Chuck Scales to discuss the science of behavior change and surprising findings from the PUSH trial, the largest kidney stone prevention trial to date. 🔗 Access resources related to this episode: https://dcri.org/blog/s2-ep-14-hard-habits-what-kidney-stones-teach-us-about-behavior-change

Closing the Gap in Cardiac Arrest Survival: Why Bystanders Matter Mar 11, 2026

Show notes

During a cardiac event, every minute without CPR reduces survival chances by 10%. In this episode, DCRI's Tyler Cope discusses a coordinated effort to train nearly 20,000 people across North Carolina in a single day and what it takes to get more bystanders to take action in an emergency. 🔗 Access resources related to this episode: https://dcri.org/blog/s2-ep-13-closing-gap-cardiac-arrest-survival-why-bystanders-matter

Our TOPPODCAST Picks

Follow Us

Stay Connected

Related Podcasts

Links

Stay Connected