Stay ConnectedThe Evolution 2.0 Podcast explores the intersection of art, technology, business, biology and spirituality. Discover new trends in evolution that change the way we think about everything. Host Perry Marshall is author of Evolution 2.0 and founded the Evolution 2.0 Technology Prize, a $10 million quest for the missing link between the information age and life itself.
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Copyright: © Perry Marshall
Edward Kelly is a neuroscientist whose research overturns the current popular definition of the mind. We had a fantastic conversation about his non-traditional path in scientific research. He is a scientist at the University of Virginia.
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Why are important conversations so difficult, and why is curiosity the greatest virtue? Dov Baron from British Columbia describes the emotional source code rules that govern our discussions about politics, religion, evolution, cancer, and relationships.
Dov Baron has a unique ability to stab at the roots of a problem and recognize its signature pattern. It’s amazing to watch him problem-solve in real-time, and he’s famous for navigating difficult conversations.
His website is dovbaron.com.
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Perry Marshall spoke at the Society for Brain Mapping and Therapeutics 21st annual conference in Los Angeles, 16 March 2024. He describes how outdated textbook evolution is inhibiting research and keeping us stuck in the old, gene-centric paradigm, and how the Polyploid Giant Cancer Cell model, advocated at a recent conference at MD Anderson in Houston, is a far more elegant model for detecting and treating cancer at the very earliest stages.
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EXACTLY 20 years ago this week, I flew to China to see my brother Bryan.
We got into an argument on a bus (a story I’ve told 1000 times). He was
bailing on his missionary career and his entire Christian upbringing, and I found this deeply upsetting.
Odds are you’ve heard my version of the story: the Evolution 2.0 book and
prize, my work in virology and cancer research, and the 1/3 of my life I spent as
a member of the science community. It has redefined my life.
People always ask how this turned out for Bryan. Odds are you have NOT
heard his side of the story! You might be surprised how attentively he has
watched as this has unfolded.
https://evo2.org/meeting-grendels-mother-in-the-spiritual-swamp/
Books on Amazon
"Understanding Living Systems" by Denis and Ray Noble
"Evolution 2.0" by Perry Marshall
"Master and his Emissary" by Iain McGilchrist
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Well-known biologist and author Sy Garte, author of the new book “Science and Faith in Harmony” joins Perry. They explore the alignment between science and faith and probe purpose in biology. They discuss the challenges of applying mathematical concepts to biological systems, recognizing that EVERY rule in biology has an exception. The two discuss changing norms in academic discourse, the new journal Biocosmos and "The Unreasonable Ineffectiveness of Mathematics in the Life Sciences.”
Sy's book: https://amzn.to/49px5MD
Sy's website: www.sygarte.com
Sy's X feed: x.com/sygarte
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"The Open Source Tissue Search Engine". This "Tissue Search Engine" will allow us to detect the early evolution of cancer -- THE KEY to reversing it. And this is why we should all be so excited by its breakthrough potential.
The best part? With a little bit of help from you... We'll be intercepting hundreds of patients with early-stage, treatable cancers in 12 months!
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What does quantum physics have to do with business decision-making, art, and AI? Perry Marshall spoke to Brian Kurtz’s Titans group in Connecticut in April and covered a dizzying range of topics from quantum physics to ChatGPT and the real problems of AI that no one seems to be talking about.
Titans Xcelerator (www.briankurtz.net/xl)
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Bob Regnerus digs into the real story behind Azra Raza's day long fireside chat in Vancouver, British Columbia Sept 23 & 24, 2023. Full information at evo2.org/vancouver.
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The overwhelming success of genetics and molecular biology in the 1970s had an unfortunate side effect. DNA became the 'be-all' and 'end-all' of biology, and “the selfish gene” became the new secular pop religion. Physiology and medicine suffered great blows from this shift. The human genome project, though valuable, did not deliver even 10% of what it promised, and the consequences to healthcare have been devastating. The new book Understanding Living Systems by Raymond and Denis Noble is an easy-to-read guide to the New Biology that brings purpose back into nature and respects the agency and autonomy of each organism and its systems.
Denis Noble website: https://www.dpag.ox.ac.uk/team/denis-noble
Ray Noble website: https://iris.ucl.ac.uk/iris/browse/profile?upi=RNOBL24
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Bryan Trilli is a serial entrepreneur who owns a company called Optimized Marketing that trains machine learning programmers to write better code. In this interview, he forcefully challenges the fiction of the “AI Singularity” showing that it’s impossible for this to happen given current technology. Consequently, we are asking all of the wrong questions. In this interview, we discuss what the real questions are.
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Occam's Razor says the simplest explanation is the best. While its application has many subtleties, it tells us that the best model of theory is the one that's most elegant and invokes the fewest extraneous explanations. Johnjoe McFadden is a professor at the University of Surrey in the UK and we discuss simplicity and the mind-bending world of quantum biology.
Website: https://johnjoemcfadden.co.uk/
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Scott Ransom’s mom grounded him from the nonfiction section of the library so that he would not be corrupted by evolutionary ideas from godless secular scientists. But the questions persisted and the fascination grew. Many years later, he wrote a book reconciling modern evolutionary science with ancient Hebrew texts. His book ...And It Was So: How Modern Science Sheds New Light on the Biblical Account of Creation goes far beyond the stereotypical debates to land in new insights.
Scott's website: www.ransombooks.com
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Did you know that 99% of the sounds in nature are at frequencies we cannot hear? Karen Bakker opens up an entire universe of sounds and communication between elephants, whales, moths, trees, tissues and even cells. The world around us is buzzing with communication and meaning that few of us ever suspected. Karen’s book The Sounds of Life: How Digital Technology Is Bringing Us Closer to the Worlds of Animals and Plants tells stories that will amaze you and she shares some of them in this interview.
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For many years, we humans have bench-marked ourselves against machines without even realizing it. Many scientists believe that humans really are just machines. Nick Chatrath sharply disagrees and says that the age of AI is going to demand that humans be more human than ever before. He insists that we've never needed a bridge between science and the humanities more than we need it right now. This extends to all aspects of leadership and organization, from startup companies to institutions and governments.
Nick Chatrath's book The Threshold: Leading in the Age of AI
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Paul Nelson of the Discovery Institute blogged about my interview with Joana Xavier lamenting that we did not fully endorse intelligent design. This created a perfect opportunity for us to sit down and talk with Paul in person and discuss our agreements and differences.
Here we explore the gray zone between “life is a miracle” and “no miracles allowed” and we ask the question: How can a design paradigm enhance medicine and science research? Joana Xavier is a researcher at University College London and is a staff member with Evolution 2.0.
Paul's blog post on Evolution News & Science Today.
Perry's Evolution 2.0 interview with Joana.
Joana’s website.
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Joe Riggio’s wife, Nancy, was given a maximum of 10 years to live in her cancer diagnosis. She lived for 17 years, most of them in a very active adventurous lifestyle. They spent $2M and pursued every alternative treatment imaginable. Here Dr. Joseph Riggio accounts in detail the journey with fascinating glimpses of many treatments that did prove effective. Our conversation closes with concluding thoughts about patient responsibility and the business of cancer.
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Reversing Cancer needs your help. Some very specific help. . .
I’ve invited Jenny Davis to talk to me about her struggles in the academic and research communities that vividly illustrate the dragon we need to slay. I know you’ll find it fascinating, but more than that, I think it’s highly likely you can help us find a solution.
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Karen Wong has a longtime interest in origins and evolution and we discuss what happens when you shift the definition of evolution. Old definition: Changes in gene frequencies acted upon by natural selection. New definition: Self-awareness at fractal levels of scale.
Evolution 2.0 by Perry Marshall Biology Transcends the Limits of Computation by Perry Marshall: https://www.sciencedirect.com/science...
The Importance of Henry H. Heng's Genome Architecture Theory by R. Furst: https://evo2.org/wp-content/uploads/2...
The True Believer by Eric Hoffer: https://www.amazon.com/True-Believer-...
Perry's conversation with Azra Raza about cancer: https://youtu.be/W2tbSS2dp9o
Cancer and Evolution Symposium with James Shapiro and Denis Noble: https://www.youtube.com/watch?v=O_nVJ...
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Joana Xavier is a rising star in the Origin of Life field. She is a researcher at University College London. She recently authored a paper with Stuart Kauffman on autocatalytic networks, which are nature’s version of M.C. Escher’s hand drawing a hand. We discuss the uneasy relationship between professional scientists and Intelligent Design and then go on to discuss conflicts in academia, science funding, and publishing.
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The book Evolution 2.0 devotes two pages to the subject of cancer and it wasn't until two years after the book was published that this fact received any attention: It is not possible to understand cancer without an accurate understanding of evolution and vice versa. This has now expanded to five very exciting research projects. This interview traces the history of all of them.
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Two leading pioneers in the field of cognition discuss the sea change that is underway in consciousness and evolution: Michael Levin is 10 years ahead of multiple fields in biology, producing extraordinary breakthroughs in limb regeneration, cancer, and bioengineering. Donald Hoffman is a champion of a new model that says the cosmos is consciousness first and matter second, not the other way around. The intersection of their ideas promises a universe of new possibilities grounded in testable hypotheses and solid engineering.
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I sat down with John Maddox who has a keen interest in information, computing, biology and evolution. John cuts right to the chase and hammers on the central issues that make biology a non-materialistic science...along with stories of numerous conflicts we've had along the way.
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Science describes things by quantifying them - weighing, measuring, and counting - but there is a dimension of being that goes beyond all these things. Science, despite its “objectivity”, is a feature of that subjective world. Anthony O’Hear OBE, a Professor of Philosophy at the University of Buckingham, UK, discusses his new book Transcendence, Creation and Incarnation and explains why faith, hope, and love make more sense of the human experience and even of science itself.
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Little do most people know that water appears to have remarkable properties that your middle school science textbooks told you nothing about, including memory and a “fourth phase”. This appears to have deep implications for medicine and biology. Gerald Pollack maintains an active laboratory at the University of Washington in Seattle and is the author of Muscles and Molecules, Cells, Gels and the Engines of Life and The Fourth Phase of Water. We discuss a mere scandalous run-in with Nature Magazine that resulted in the demise of a certain researcher’s career.
Links:
The Fourth Phase of Water book on Amazon
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Richard Jacobs of the Finding Genius Podcast has written a new book called Finding Genius: Understanding Cancer: 30 Questions, 70 Geniuses, 200+ Amazing Insights in which he interviews 70 scientists covering 30 questions about cancer research overlayed with his own personal experience of thyroid cancer. Hint: The cancer treatment ladder is leaning against the wrong wall. Beware of donuts and snack machines.
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December 21, 2021, is the 50th anniversary of President Richard Nixon declaring that cancer was going to be ended by 1976. Many media outlets are celebrating progress when, in fact, the progress isn’t all that impressive. Azra Raza, Columbia university oncologist, speaks candidly about her entry into the cancer field at age 24, the years that have passed, and incredibly promising research that has now commenced from the 60,000 tissue samples that she has collected from her patients across 30 years of practice. Here she describes her quest to catch the first cancer cell red-handed as it is forming.
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John Lennox is an Oxford mathematician who is the author of the new book Cosmic Chemistry. He's written many books about the relationship between science and religion and has debated Richard Dawkins and Christopher Hitchens. His new book candidly surveys the current state of evolutionary theory. Notable chapters include reviews of work by Denis Noble and James Shapiro. In this conversation that we had on the Oxford campus, John recounts his history of asking the big questions.
LINKS:
John Lennox's University of Oxford Faculty page
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In September 2021, a dozen entrepreneurs gathered in Chicago and had a seminal 3-day discussion and commissioning for solving the world’s most thorny, intractable issues. Bob Regnerus was there and here we discuss what happens when entrepreneurs shift their focus from creature comforts to curing the most wicked problems of the world.
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It is seldom mentioned that Charles Darwin's Origin of Species failed to deliver what the title promised. The mechanisms in his book only deliver microevolution but not macroevolution. Henry Heng discovered a major puzzle piece in his study of cancer and it's called "Genome Chaos". Rafe Furst, a longtime collaborator of Henry's, joins us in exploring the real mechanism of evolutionary change and the true reasons for sexual reproduction. Rafe wrote a summary of Henry's work here. You can buy Henry's book here.
Rafe and Henry are starting a working group to explore evolutionary state-of-the-art breakthroughs and you can join their list by sending an email to genomearchitecturetheory@gmail.com.
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Doru Paul of Cornell University is one of those very rare people who has both treated over 10,000 cancer patients as their doctor and simultaneously holds a kaleidoscopic view of a huge range of research, theories, and literature. Today we talk about the many competing models and their pros and cons. And, finally, he answers the question: “What kind of medical policies would you put in place if you could start your own country from scratch?”.
LINKS:
Official version: https://www.sciencedirect.com/science/article/abs/pii/S0079610721000419
Free version: https://evo2.org/cancer-as-a-form-of-life
Credentials: https://weillcornell.org/doru-m-paul-md-phd
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Today I don’t have a guest, but what I do have is a really excellent PDF submitted to me by a
Perry Marshall. Perry, has been a really successful marketer, I’ve been following him for
12 years, he has been doing it for maybe, close to 20 years. He started off teaching Google
AdWords, Google Pay-Per-Click, and moved on to Facebook advertising, and eventually, I started
hearing from him that he was studying evolutionary biology and I read his book, Evolution 2.0. It
brought out a lot of super interesting topics in biology that I just didn’t know about and it was
part of my inspiration to do the podcast as well and to this day, having done almost 3,000
interviews, I credit Perry and Evolution 2.0 for kind of getting me started on the path. So Perry
now has been working on cancer, not directly but he is working on helping to promote a new
and what I think is probably a better understanding of cancer and as you know, if you are a
listener of this podcast, I am getting close to finishing my book on cancer....
https://bit.ly/high-speed-evolutionary-mechanisms-pdf
https://mma.prnewswire.com/media/1583603/Natural_Code_popular_evolution_books.pdf
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Psychic phenomena have been meticulously documented in hundreds of controlled studies since the 1980s. Mainstream science publications resist acknowledging this but the quality and quantity of evidence is overwhelming. Dean Radin, who has a bachelor’s degree in electrical engineering and a Ph.D. in Psychology, began discovering this decades ago and founded the Institute for Noetic Sciences. He recently joined forces with eminent scientist Stuart Kauffman to harmonize the observations with quantum theory. In this paper, the two scientists swing for the fences and attempt to unify consciousness, psychic phenomena, and quantum mechanics. https://arxiv.org/abs/2101.01538 Dean and I discuss the implications of this.
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There are very very few people who can slice through the jargon of molecular biology and explain how cells talk to each other in a way that a high school student can understand. But Jon Lieff has done exactly that and his book, NAME, is a guided tour of a microscopic world that is bursting with life... and stories...This book may change the way you see everything.
Jon Lieff's Website: https://jonlieffmd.com/
Jon Lieff's Book: The Secret Language of Cells
https://jonlieffmd.com/book/the-secret-language-of-cells
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A new book by MIT Press stresses the urgency of approaching cancer from new angles. Some are completely new. Others are 100 years old and never given the attention they deserve. Bernhard and I discuss his motivations for taking on this project and how complex systems are much more subtle than we humans prefer to believe.
Bernhard Strauss' Book: Rethinking Cancer
https://mitpress.mit.edu/books/rethinking-cancer
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Jenny Davis is a professional athlete from Scotland who found out she had bowel cancer 9 months ago. She tells her very personal story of chemotherapy treatments, introspection, detox, and our broken medical system.
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John Sonmez interviews Perry Marshall and they discuss why it’s impossible for computers in their current form to become conscious; how modern mathematics speaks in a new way to age-old questions about free will; the nature of consciousness; the origin of life and the very nature of reality itself. All this is based on Perry’s paper “Biology transcends the limits of computation.
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Eric Kuelker Ph.D. R.Psych. discusses reliable but little-known research linking cancer and heart disease to traumatic life events and stress. It turns out that psychotherapy and relationship repair reduces the chances of cancer and factors like marriage extend life more than medical treatments do. This may extend it down to the cellular level.
Eric’s website is https://psychologicalinjuryindex.com/
References:
Hughes K, Bellis MA, Hardcastle KA, Sethi D, Butchart A, Mikton C, Jones L, Dunne MP. (2017) The effect of multiple adverse childhood experiences on health: a systematic review and meta-analysis. Lancet Public Health. Aug;2(8):e356-e366. https://pubmed.ncbi.nlm.nih.gov/29253477/
Roberts AL, Huang T, Koenen KC, Kim Y, Kubzansky LD, Tworoger SS. (2019) Post-traumatic stress disorder is associated with increased risk of ovarian cancer: A prospective and retrospective longitudinal cohort study. Cancer Res. Oct 1;79(19): 5113-5120. https://pubmed.ncbi.nlm.nih.gov/31488422/
Lu D, Sundström K, Sparén P, Fall K, Sjölander A, Dillner J, Helm NY, Adami HO, Valdimarsdóttir U, Fang F. (2016). Bereavement is associated with an increased risk of HPV infection and cervical cancer: An epidemiological study in Sweden. Cancer Res. Feb 1;76(3): 643-51. https://pubmed.ncbi.nlm.nih.gov/26634926/
Flaherty RL, Owen M, Fagan-Murphy A, Intabli H, Healy D, Patel A, Allen MC, Patel BA, Flint MS. (2017) Glucocorticoids induce production of reactive oxygen species/reactive nitrogen species and DNA damage through an iNOS mediated pathway in breast cancer. Breast Cancer Res. Mar 24;19(1):35. https://pubmed.ncbi.nlm.nih.gov/28340615/
Morath J, Moreno-Villanueva M, Hamuni G, Kolassa S, Ruf-Leuschner M, Schauer M, Elbert T, Bürkle A, Kolassa IT. (2014) Effects of psychotherapy on DNA strand break accumulation originating from traumatic stress. Psychotherapy and Psychosomatics. 83(5):289-97. https://pubmed.ncbi.nlm.nih.gov/25116690/
Bellis MA, Hughes K, Ford K, Ramos Rodriguez G, Sethi D, Passmore J. (2019) Life course health consequences and associated annual costs of adverse childhood experiences across Europe and North America: a systematic review and meta-analysis. Lancet Public Health. Oct;4(10): e517-e528. https://pubmed.ncbi.nlm.nih.gov/31492648/
Ziegler C, Richter J, Mahr M, Gajewska A, Schiele MA, Gehrmann A, Schmidt B, Lesch KP, Lang T, Helbig-Lang S, Pauli P, Kircher T, Reif A, Rief W, Vossbeck-Elsebusch AN, Arolt V, Wittchen HU, Hamm AO, Deckert J, Domschke K. (2016). MAOA gene hypomethylation in panic disorder: Reversibility of an epigenetic risk pattern by psychotherapy. Transl Psychiatry. Apr 5;6(4):e773. doi: 10.1038/tp.2016.41 https://pubmed.ncbi.nlm.nih.gov/27045843/
Roberts S, Lester KJ, Hudson JL, Rapee RM, Creswell C, Cooper PJ, Thirlwall KJ, Coleman JR, Breen G, Wong CC, Eley TC. (2014). Serotonin transporter [corrected] methylation and response to cognitive behavior therapy in children with anxiety disorders. Transl Psychiatry. Sep 16;4(9):e444. https://pubmed.ncbi.nlm.nih.gov/25226553/
Roberts S, Keers R, Breen G, Coleman JRI, Jöhren P, Kepa A, Lester KJ, Margraf J, Scheider S, Teismann T, Wannemüller A, Eley TC, Wong CCY. (2019). DNA methylation of FKBP5 and response to exposure-based psychological therapy. Am J Med Genet B Neuropsychiatr Genet. Mar;180(2):150-158. https://pubmed.ncbi.nlm.nih.gov/30334356/
Levy-Gigi E, Szabó C, Kelemen O, Kéri S. (2013). Association among clinical response, hippocampal volume, and FKBP5 gene expression in individuals with posttraumatic stress disorder receiving cognitive behavioral therapy. Biol Psychiatry. Dec 1;74(11): 793-800. doi: 10.1016/j.biopsych.2013.05.017 https://pubmed.ncbi.nlm.nih.gov/23856297/
Quidé Y, Witteveen AB, El-Hage W, Veltman DJ, Olff M. (2012). Differences between effects of psychological versus pharmacological treatments on functional and morphological brain alterations in anxiety disorders and major depressive disorder: A systematic review. Neurosci Biobehav Rev. Jan;36(1): 626-44. https://pubmed.ncbi.nlm.nih.gov/21963442/
Bossini L, Santarnecchi E, Casolaro I, Koukouna D, Caterini C, Cecchini F, Fortini V, Vatti G, Marino D, Fernandez I, Rossi A, Fagiolini A. (2017). Morphovolumetric changes after EMDR treatment in drug-naïve PTSD patients. Riv Psichiatr. Jan-Feb;52(1): 24-31. https://pubmed.ncbi.nlm.nih.gov/28287194/
Aizer AA, Chen MH, McCarthy EP, et al. Marital status and survival in patients with cancer. (2013) J Clin Oncol. 31: 3869‐3876. https://pubmed.ncbi.nlm.nih.gov/24062405/
Mirosevic S, Jo B, Kraemer HC, Ershadi M, Neri E, Spiegel D. (2019). "Not just another meta-analysis": Sources of heterogeneity in psychosocial treatment effect on cancer survival. Cancer Med. Jan;8(1): 363-373. https://pubmed.ncbi.nlm.nih.gov/30600642/
https://www.health.harvard.edu/heart-health/the-genetics-of-heart-disease-an-update
Levin M (2019) The Computational Boundary of a “Self”: Developmental Bioelectricity Drives Multicellularity and Scale-Free Cognition. Front. Psychol. 10:2688. https://pubmed.ncbi.nlm.nih.gov/31920779/
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Rob Berkley left this earth in December 2019 as a result of cancer. 58. Rob was THE most empathic and warm-hearted individual in the entire marketing space (I’m not exaggerating). When you would sit down with him you would feel his warmth focusing on you like an infrared heat lamp. He was one of my most valuable business advisors. Being trained by him and Victor Cheng was like having Oprah and Stephen Hawking together in the same room.
Stormy weather nearly prevented me from making his memorial at Martha’s Vineyard, but I managed to snag the boat ride and I’ll never forget the December 18 solstice sun streaming through the windows at his somber yet joyful gathering.
The other thing I will never forget is meeting his wife Debbie for the first time, right there at his memorial service. I had heard much about her, and she had heard about me, but we had never crossed paths.
I approached her in their kitchen and introduced myself. “Perry! I am so delighted to meet you!” She faced me squarely, looked deep into my eyes, and connected, human to human. I instantly felt the jolt of her conviction and aliveness. She wrapped her arms around me, embraced me, and welcomed me as though I were a friend of 25 years. Her energy was so palpable I was momentarily startled.
It only makes sense that Rob would marry a woman like Debbie.
Today I would like to share Rob’s last interview with you: a very candid conversation between Rob, Debbie, and their caregiver and collaborator Meredith, describing humility and courage in the face of a terminal diagnosis.
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Mark Chenoweth is a theologian with a particular interest in St. Maximus the Confessor (700 AD) and St. Gregory of Nyssa (400 AD) who wrote about life on earth as a goal-directed process as opposed to a series of divine miracles. Their ideas were very much in line with the ancient Greeks who have been greatly under-estimated by modern thinkers. Here we hear Mark's story of being drawn into evolutionary science and what implications this has for modern people.
Mark's paper is called "A Maximian Framework for Understanding Evolution".
Mark's Bio
Mark Chenoweth received his M.Div. and Th.M. from St. Vladimir’s Orthodox Theological Seminary and is an adjunct professor at St. John’s University in New York. His articles have been published in scholarly journals such as St. Vladimir’s Quarterly, and he is hoping to soon begin a dissertation on the theology of St. Maximus the Confessor.
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How does a psychology prof find herself writing a book on cancer evolution?
And what does this have to do with the Zombie Apocalypse? Today’s
conversation is with Dr. Athena Aktipis from Arizona State University, who
hosts the Zombified podcast. We explore the not-so-obvious byproducts that
emerge you change the rules of cooperation and convention-defying
breakthroughs in cancer treatment.
WEBSITE LINKS:
Athena’s personal website: http://www.athenaaktipis.org/
Zombified podcast: www.Zombified.org
The Cheating Cell: How Evolution Helps Us Understand and Treat Cancer
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Sam Devis is a former pastor who experienced a faith deconversion a couple of years ago similar to that of my brother, Bryan. After reading Evolution 2.0, Sam and I got together to discuss my journey from fundamentalism to where I am today. We cover many fascinating aspects from Darwinist Jerry Coyne's outrage to the nature of fundamentalist belief structures to evolution and entrepreneurship to questions about the cosmos and free will. Sam's website is https://linktr.ee/whenbeliefdies.
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Einstein’s theory of relativity overturned Newtonian physics in the early
1900s. Nevertheless, “Newtonian” thinking has remained firmly entrenched in
science. Certainly, all scientists now agree that at the subatomic level and at
near light speed, quantum physics overtakes Newtonian physics. But this
has had very little effect on biology and has done nothing to overturn the
“reductionist” view of science, which says that everything is merely the sum
of its parts and all can be modeled by mathematics.
Stuart Kauffman and computer scientist Andrea Roli have written a new
paper that proves evolving biology in principle cannot be reduced to
computation. This is as devastating to materialistic science as Gödel’s
Incompleteness Theorem was to mathematics. In fact, it is equivalent -
because it shows that evolving organisms embody incompleteness.
Induction, not a deduction. And induction cannot come from deduction;
therefore biology is not strictly computational.
Thus Kauffman and Roli have pulled the rug out from under ultra-traditional
views of physics. (Not everyone is going to be happy about this.) Here, Perry
Marshall and Stuart Kauffman jazz improvise on the vast implications of this
new, holistic view of the universe.
You can read their paper “The World is Not a Theorem” at
https://tinyurl.com/stuartkauffman
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Today if you’re diagnosed with Stage 3 or Stage 4 cancer, your chances of surviving are no better than if you lived in 1930. But your chances are 100 times better when catch it early.
What if you could catch cancer SUPER early - years before any obvious indication of a problem?
And what if you could then solve the problem at its roots so it never recurs at all?
Azra Raza is an oncologist at Colombia University and author of The First Cell: The Human Costs of Pursuing Cancer to the Last. Here she describes the First Cell Project. This is a collaboration with world class cancer researchers who have discovered how to identify “Giant Cells” that PREDATE and predict the generation of tumors YEARS in advance.
You’ll be privy to the incredibly moving story of Andrew, her daughter’s best friend who died of brain cancer at age 24… and the systemic problems that continue to plague the cancer field and repeat the tragedy of Andrew. Here we discuss why only outsiders will solve these problems.
WEBSITE LINKS:
Be sure and watch my previous interview with Azra Raza at www.evo2.org/azra - it’s a barn burner and provides important background that gives rich context to this new discussion.
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This is a unique show in the Finding Genius series. Podcast founder and host Richard Jacobs cites Perry Marshall’s ideas as the impetus for starting the Finding Genius podcast.
In this discussion, listeners can learn more about why and hear about the Cancer & Evolution Symposium Marshall has helped construct on cancer and evolutionary biology.
He explains:
Perry Marshall is an author and highly influential business consultant with an electrical engineering background. In this discussion, he connects the foundational ideas in Evolution 2.0 with cutting-edge cancer science. Marshall lost his father to cancer at age 17 and has followed the theories behind its treatment ever since. He reminds listeners that common cancer therapy treatment only works routinely with early-stage cancer.
Alternatively, he says that when cancer reaches stages 3 and 4, survival chances are not that much better than they were in 1930. Therefore, there must be a lag in how we are addressing serious cancer diagnoses. This lag is connected with a traditional view of passive evolutionary theory rather than theories like that of Professor Henry Heng, who claims evolution is actively engineered by organisms themselves; in addition, they are able to pass those engineered traits to their offspring.
Henry Heng was one of the speakers at the Cancer and Evolution Symposium along with Columbia University Medical Center’s Azra Raza and evolutionary theorist James Shapiro from the University of Chicago. Dr. Heng connects this theory of evolution and cancer, noting that treatments like chemo destroy about 98% of the cancer cells while the few remaining develop massive wholesale restructuring of their DNA and are then more equipped to spread and survive. Importantly, this restructuring is active rather than a random accident of mutations.
Marshall explains these ideas in more detail and discusses other topics covered by the speakers. He describes the symposium as a world-class collection of cancer and evolutionary theorists coming together to address cancer evolution and disable the cancer treatment lag. The symposium took place October 14th through 16th, 2020.
To learn more - see the symposium website: cancerevolution.org.
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Perry Marshall was invited to Notre Dame Business School to present at a masters level class on new trends in medicine and biology. This talk canvases a spectrum of issues from COVID- 19, virus evolution and the dark underbelly of cancer research.
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Perry Marshall discusses avenues of research that may uncover the mystery of what makes life alive.
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In 2019, I interviewed Joel Salatin, advocate of alternate farming. Our conversation prompted me to predict for the decade 2020 - 2029 that laws would be overturned making local food production and distribution a rising economic force. I didn't know then that COVID was about to speed that process up 10X. Here's what's happened since then.
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Dr. Michael Levin of Tufts University crosses many disciplines: computer science, embryo development, cancer and tumor research; limb regeneration; evolutionary theory and neural networks. If you watch some of Michael's fascinating talks at https://ase.tufts.edu/biology/labs/levin/research/presentations.htm he'll take you down his magical rabbit hole including worms that grow new heads when you cut them in half, tumors that heal themselves and eyes planted on tails that actually work. In this interview, Michael explodes the myth that "we've got it mostly figured out." The truth is closer to 1% understanding and 99% is Dark Matter. Discover Michael's research at https://allencenter.tufts.edu/our-team/michael-levin/ and http://www.drmichaellevin.org.
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Azra Raza treated cancer patients for 30 years, but not even the loss of her Oncologist husband could provoke her to write a book. It took the death of her daughter’s dearest 22 year old friend - when suddenly she realized she had to speak up. Here we discuss the one most important thing that The System overlooks - THE PATIENT’S ANGUISH - and speaks out about the state of cancer research in the 21st century. Groupthink, sexism, ignorance of history, and absence of empathy… and no one is in charge.
A quarter-trillion dollars later, we’re still carrying out the same punishing treatments we were doling out in the 1970s - where life extensions of six weeks are heralded as "breakthroughs." We discuss the “Cancer Cambrian” and the great black hole that is our grasp of cancer cellular evolution. Finally, witness Azra’s dream of a superior system for detecting and beating cancer.
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Addy Pross is a Chemist at Ben Gurion University in Israel. He's author of "What is Life: How Chemistry Becomes Biology" by Oxford University Press. Here we enjoyed a great conversation about his specialty, Systems Chemistry, a new branch of science that enables us to build complex networks of chemical reactions like those found inside of cells. We explore the unanswered questions that continue to perplex scientists of all kinds.
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Lynn Margulis, who died in 2012, was a piercing luminary in the history of evolutionary theory. She overturned the money changer's tables in the temple of science and infuriated a lot of people. But history has continued to vindicate her. In this interview, she and Conner explore a very different way of thinking about life itself and you’ll hear her brilliant mind and feisty posture.
Conner Habib's Patreon: Patreon.com/connerhabib
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William Miller tells his story of being seduced into evolutionary science by a mysterious female named Sue.
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Michael Behe infuriated traditional Darwinists with his concept of irreducible complexity more than 20 years ago. He argues instead for Intelligent Design. But what does ID really mean? Is it a puff of smoke? A perfectly executed pool shot at the start of the Big Bang? External intervention at various points along the way? Intrinsic cellular intelligence? Perry Marshall and Michael Behe discuss where to draw the dotted line.
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Joel Salatin is a "Christian Libertarian Environmentalist Capitalist Lunatic" who is re-inventing the way food is grown, distributed and consumed. Here we examine how current legislation is based on 1906 technology, and the new culinary entrepreneurship that is expanding as we break the shackles of 19th century "Darwinian" agriculture. Discover Joel at https://www.thelunaticfarmer.com.
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Michael Heiser, whose podcast “The Naked Bible” got five million downloads this year, studied Hebrew at the University of Wisconsin and was confronted with a dilemma: How do you reconcile common modern interpretations with the nuances of what the ancient texts actually say? His journey revealed an Unseen Realm that is very different from the assumptions modern people bring to these stories. We had a delightful conversation about implicit assumptions.
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How is it that good scientific theories can take 200 years to catch on while bad theories hang on for a century...even when empirical evidence that could settle the issue is close at hand? Rich Jacobs of the FutureTech Podcast asked if we could talk about how scientists can better market themselves and this is the conversation that unfolded. {LINK to FutureTech Podcast: https://www.futuretechpodcast.com/}
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What does Jordan Peterson really believe about religion? Is “the Intellectual Dark Web” just another 2018ism? Are archetypes enough to save the next generation? Esther O’Reilly achieved fame in the blog world with her incisive commentary about Jordan Peterson. I caught up with her and we explored the no man’s land between the faith world and the academic world.
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Kevin Freeman, a global financial analyst commissioned by the Pentagon, is one of the world’s leading experts on the issues of Economic Warfare and Financial Terrorism. Here, Kevin and I explore the uses and abuses of AI, algorithms, surveillance technology, and ways foreign governments encroach on people who live in allegedly "free" countries. Website: www.EconomicWarroom.com
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Some science teachers avoid or minimize evolution. Others ram it down their students' throats. Is there another way? Michael Reiss, who is both an evolutionary biologist and ordained priest in the Church of England, explains his method of evolution as a sensitive issue. With the growth of Muslim populations in the UK and Europe, this isn't just an American issue - it's a hot topic everywhere.
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Sy Garte is author of The Works of His Hands: A Scientist's Journey from Atheism to Faith. He is a PhD biologist who has published over 200 papers and worked as a grant reviewer for the NIH. Here he tells his story of transforming from militant atheism to faith and why science itself rejects materialism.
Sy Garte's Website: www.thebookofworks.com
Twitter @sygarte
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Daniel White Hodge confronts racism in America as seen through the eyes of a black man in a mixed race marriage, communication arts professor and hip hop music. Using Charles Darwin’s racism as a jumping off point, we explore the complicated question of race polarization in America. https://www.whitehodge.com/
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What do you think about God when your newborn son dies in your arms? Khaldoun Sweis gives a candid telling of his life’s traumatic moment.
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“When Perry’s brother quit his missionary job and abandoned Christian faith, this plunged Perry into a deep crisis of questioning everything himself. And he decided to put Christian beliefs on the biggest public anvil he could find and invite the whole world to swing a hammer. This became an email list of two hundred and fifty thousand people, millions of website visitors, seven years in the largest atheist discussion board in the world, and in this talk he describes his journey through the darkness and what was left after the smoke cleared.
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Why is Old Testament bible god so mean and nasty? Why is nature so ruthless and unforgiving? Where do we get our ideas about a kinder, gentler society? Perry Marshall and Paul Braoudakis take the gloves off.
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At the Royal Society in Great Britain on May 31, 2019, Perry Marshall announced the Evolution 2.0 Prize was being doubled to $10M. Present in the room were Denis Noble, Fellow of the Royal Society, Dr. Paul Flather of Oxford, Clive Cookson Science Editor of the Financial Times, Investor Kevin Ham and several other scientists from the UK. Perry and Denis discuss the thinking behind the prize and the conversation includes open Q&A.
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Denis Noble, one of the judges for the Evolution 2.0 Prize, discusses in this interview why we can't just put lipstick on a pig - why the public needs to be aware that evolutionary theory has undergone a revolution, and how this affects not only religious and philosophical discussions but policies and actions in medicine economics and politics.
This interview was conducted by Ryan Bissett of Chasing Reality. Ryan has a PhD in molecular biology and five years of experience in biotech, but he eventually traded everything to go on a trajectory he could not have imagined. He lived in a van, packed wild food, and even lived as a Hare Krishna monk for five years. His aim now is to understand, "how can I synthesize my scientific training with my newfound narrative of existence?" You can check out his podcast as he interviews thinkers from different field of inquiry about fundamental questions of consciousness and reality, here: https://www.youtube.com/channel/UChz-a9985r_s6n2EeC6zTgg
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Perry responds to the 11-page review of Evolution 2.0 in CRSQ, the Creation Research Society Quarterly, written by Royal Truman:
https://creationresearch.org/wp-conte...
Zach Spear interviews Perry about growing up in a conservative evangelical church; creationism, evangelical theology, evolution, miracles, cosmology; a new way to look at Adam and Jesus, and the arc of human culture.
Click here to get 3 free chapters - a Communication Engineer’s adventure through the creation-evolution divide:
https://evo2.org/
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Brenda Dunne was a scientist at Princeton University's Engineering Anomalies Research Lab for 28 years, where she and her colleague Robert Jahn performed extensive experiments on telekinesis (displacing objects and changing the behavior of machines by concentration), remote perception (perceiving objects and locations at great distance) and precognition (knowing future events before they happen). They documented with 99.999% statistical confidence that consciousness interacts with matter in undeniable but presently unexplained ways. Here she discusses their work and the implications of a conscious world being complementary to the physical world. Discover more about Brenda's remarkable work at www.icrl.org.
Books:
Consciousness and the Source of Reality
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Iconoclast, polymath, renegade and world-class chemist, Steve Benner engineered a new breed of DNA with 8 nucleotide options instead of four. This exponentially increases its data capacity and it’s called Hachimoji DNA.
What are the implications of this? Steve sounds off about the conflict between research and advocacy, and the great power of shattering paradigms and admitting what we don’t know.
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While working in plant research at Cambridge, Rupert Sheldrake became dissatisfied with existing materialistic theories of science. This led him to develop his theory of morphic resonance. Sheldrake has become a leading proponent of switching from a reductionist scientific paradigm to a holistic paradigm. In this conversation we discuss scientific experiments that definitively show phenomena we have no way of explaining at present. Find out more about Rupert at www.sheldrake.org.
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Frank Visser became a friend and colleague of Ken Wilbur in the 1980s and wrote a book about his work. In this conversation, we discuss Frank’s departure from Ken Wilbur’s insistence that life itself and evolution are manifestations of the divine. We explore the question of how theology informs specific evolutionary theories. Does invoking God further science? Frank and Perry take a look at the nuances of Darwinism versus Design
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Michael Behe's "Darwin Devolves" asks: Has Darwin solved the design problem in biology? Behe says absolutely not, and backs his position with detailed examples. Furthermore, nobody has really solved the famous problem of "irreducible complexity" that Behe described in "Darwin's Black Box." But Perry Marshall insists Behe has still omitted vital details and landmark experiments. Bill Cole works closely with Behe, so Perry and Bill discuss: Will Behe's approach be effective in addressing the shortcomings of mainstream science?
Where Did Life Come From? Perry Marshall’s Evolution 2.0 at Penn State University
https://evo2.org/where-did-life-come/
"Living Organisms Author Their Read-Write Genomes in Evolution" by James Shapiro - www.tinyurl.com/jamesshapiro
"Evolution 2.0: Breaking the Deadlock Between Darwin and Design" www.budurl.com/ev20
The Evolution 2.0 Prize $5 million www.herox.com/evolution2.0
Links from Bill Cole:
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Two world class physicists from Oxford, together with philosophy professor Hans Halvorson from Princeton, integrate faith and science in their new book "It Keeps Me Seeking." Andrew Briggs specializes in nanomaterials and quantum information, and Andrew Steane made a key discovery which was necessary to make quantum computing possible. I sat down with Briggs and Steane in Oxford where we enjoyed a wide ranging discussion about the intersection of the measurable rigors of science and the high aspirations of spirituality.
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Former president of Google China, Kai-Fu Lee, describes the rapid acceleration of artificial intelligence (AI) technology in China. He discusses what AI is and is not capable of and how AI challenges us to get much more clarity about what it means to be human. His new book AI Superpowers: China, Silicon Valley, and the New World Order presents a much more realistic view of the future than the typical science fiction of most journalists.
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The opening shot of my book Evolution 2.0 is an argument between me and my brother about evolution. Bryan had been a missionary in China, but in four years he went from right-wing Christian seminary grad to almost atheist.
He was dragging me with him. I wasn’t enjoying it, but I knew I had to be intellectually honest.
I found myself retreating to what I know best, which is science. I said, “Bryan, look at the hand at the end of your arm. I’m an engineer, and your hand is a fine, fine piece of engineering. You don’t think your hand is an accumulation of random accidents, do you?”
Bryan was good and ready for that question, and he pushed back with a standard-issue Darwinian answer. His answer didn’t quite jive with my experience… but I admitted my intuitions could be wrong. So instead of arguing, I decided to dive down the rabbit hole. I resolved to get to the hard truth, and follow it wherever it carried me.
Our argument in the back of a Chinese bus led to a book that took six years to write, a technology prize, and a quest for life’s origin that now includes some of the world’s most renowned scientists at top universities. You can read the rest of that story in Evolution 2.0.
But… what about Bryan?
Recently we held a business seminar where we presented Evolution 2.0 and the technology prize as a case study. Everyone at the seminar was asking Bryan “OK, so what’s your story?”
Here is Bryan’s story…
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Wynand De Beer has written a beautiful book From Logos to Bios. He links diverse ideas from the ancient Greeks and their ideas about mathematics and life with recent evolutionary discoveries like convergence and orthogenesis. He offers a new framework for evolutionary models that recognize the deteriorating state of the Darwinism, replacing it with a more elegant model.
Perry Marshall interviews Wynand, who shares not only surprisingly relevant insights from ancient philosophers, but also his personal story.
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Many have claimed atheism was only incidental to the operation of communism under Lenin, Stalin and the old Soviet Union. Victoria Smolkin's new book "A Sacred Space is Never Empty" is the first book to closely examine the role of atheism in Russia. She explains why the Soviet government promoted atheism so assiduously and expended great efforts to crush religion. In this conversation, Dr. Smolkin approaches this issue with scholarly precision, and explains the true meaning behind her book's intriguing title.
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Podcaster Joe Rogan sat down with Elon Musk. They discussed AI & Evolution. (Full interview at https://youtu.be/ycPr5-27vSI.)
Entrepreneur Tim Berthold mentioned the Elon interview to bestselling author, speaker, engineer and strategy consultant Perry Marshall.
Perry explains why the "Singularity" (the prediction that we're all going to upload ourselves into the cloud someday and live on the web)
is a crackerjack distraction from the REAL problems. Perry is acutely aware of the *real* dangers after teaching over one million marketers
how to advertise on Google. Sleep with one eye open.
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I just did a rock-em-sock-em interview with Audie Cashion of World Peace Center. We dug into…
And a lot more. Listen to the interview here!
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For a century, the belief was that genetic information built organisms, never the other way around. A new paper by Denis Noble definitively proves otherwise. The paper is called “Central Dogma or Central Debate.” In this interview, Denis explains the revolution that is going on in genetics.
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David Quammen's book "The Tangled Tree: A New History of Life" tells the story of evolution through the eyes of Carl Woese, a not-terribly-famous but truly ingenious revolutionary who flipped evolution on its side, literally 90 degrees. He upended Darwin's famous tree of life, showing that genes can come from almost anywhere. Woese's contributions are believed by some to be as great as Darwin's. The view of evolution that Woese brought truly was a genuine revolution. Here, David Quammen engages with Perry Marshall in a wide ranging conversation about who the real heroes in evolutionary science actually are.
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Claude Shannon made our modern digital world possible. He wrote a landmark paper called "The Mathematical Theory of Communication" which gave birth to computer networks, cell phones, compact discs, digital recording and video. It also lent huge insights into genetics and biology. Rob Goodman & Jimmy Soni have written the first full biography of Claude Shannon and it’s great. It’s called "A Mind at Play: How Claude Shannon Invented the Information Age". In this video, we discuss the quirky world of one of the 20th Century's great geniuses.
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Did people in the Middle Ages believe the Earth was flat? Were Christians the enemy of Copernicus? Are science and religion enemies? Dr. Ted Davis, professor of the history of science and religion tells us the real story.
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The Young Earth Creationist and His Curious Daughter.
Dinner with my friend Bob, a Young Earth Creationist, and his 12 year old daughter Melanie takes a peek at how evolution really works.
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What we know about codes has sweeping implications for not only science but philosophy and religion as well. We define terms and make clear who should read this book, and who will likely be too offended to bother reading it.
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In four years, my younger brother Bryan went from seminary grad and missionary in China to the doorstep of atheism - and he was dragging me with him. This was an earthquake for everyone in my family, because we’re pastor’s kids.
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Because I’m an Electrical Engineer, I decided to let science decide this for me: Does nature really point us to atheism? Or does science favor faith? Darwinian theory is consistently challenged by doctors and engineers. Does that mean the engineers know something the biologists don’t? Or do the biologists know something the engineers don’t know? I resolved to find out. And I also encountered strong evidence for an evolutionary history of the earth.
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My first business was building stereo equipment and I was selling my brand in a retail store when I was 17. Later I worked in manufacturing, acoustics, and digital networking. What does engineering tell us about evolution?
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100 years ago, biologists discovered they could generate DNA mutations with radiation, which was easy to do. They were excited because they believed they could now accelerate evolution. They tried experiments with fruit flies for decades. They learned a great deal about which genes perform certain functions… but as far as generating evolutionary events, those experiments were a total failure. There had to be something more to evolution that we didn’t understand.
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I had a huge epiphany when I realized that everything I knew about 1s and 0s as a communication engineer applied to DNA. This sliced through a LOT of nonsense a lot of people were spouting about evolution. It also indicated who I could safely listen to and what I was likely to find as I dug deeper.
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A friend accidentally meets the inventor of digital imaging in an Oregon coffee shop, and the world’s first digital photo is Russell Kirsch’s son Walden in 1957. This sparks insight into the early history of life.
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Barbara McClintock discovered corn plants can re-program their own DNA in 1944. But her colleagues thought she was crazy so she took her work underground for 20 years. But she won the Nobel Prize in 1983. Turns out nearly every cell in existence can cut, splice, and re-arrange its DNA - reprogramming itself when times get tough.
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Creationists say evolution has never been observed and cannot create new species. But if you know what to do, you can make new species at will with hybrids. A major blade in the evolutionary Swiss army knife.
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How to win the Evolution 2.0 Prize.
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Referred to as “Science’s Unruly Earth Mother”, a “vindicated heretic”and a “scientific rebel”, Lynn Margulis was an American evolutionary theorist, biologist, and science author. She was the primary modern proponent for symbiosis in evolution.
Throughout her career, Margulis’ work aroused intense objection (one grant application elicited the response, “Your research is crap, do not bother to apply again”,) and her formative paper, “On the Origin of Mitosing Cells,” appeared in 1967 – after being rejected by numerous journals.
Her papers are now permanently archived in the Library of Congress, and she is considered to be one of the 20th century’s most important inspirational leaders.
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Purpose & Desire: What Makes Something “Alive” and Why Modern Darwinism Has Failed to Explain It is yet another in a line of PRO-evolution books by highly credible, mainstream biologists who are stepping forward and insisting that The Emperor really does have No Clothes.
Turner is not in any way, shape or form opposed to the idea of evolution itself. He’s no creationist; he’s a professor at State University of New York. In fact he insists we are obligated to study and understand purpose, just to even make sense of evolution itself. And there are so many mechanisms we need to study.
The book is extremely well written and congenial. Like Shapiro and Noble, Turner is a gentleman through and through, and does not go on a shaming rampage. This book is no rant. Rather, he invites you to really think and decide for yourself.
And like those before him who first cracked the Berlin wall, he carves a middle path between the two extremes. I predict that in 2-5 years, hordes of former prisoners of Neo-Darwinian dogma will make their escape to freedom.
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How do you get to the bottom of an impossibly murky topic and find the truth? A 1300 year old story from Medieval English tells us how.
In a private meeting with entrepreneurs from around the world, Perry Marshall explains how the ancient story of Beowulf teaches us how to solve scientific technological and business problems.
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