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Cardiovascular risk evaluation for non-cardiac surgery, guidelines | EBPOM 24 Sep 02, 2024

Show notes

Guideline evolution is driven by ongoing research; recent studies like PeriOperative ISchemic Evaluation-3 Trial (POISE-3) and trials such as OPtimisation of Peri-operaTive CardIovascular Management to Improve Surgical outcomE II (OPTIMISE II) trial may influence recommendations on hemodynamic management and the use of tranexamic acid. Future guidelines are expected to integrate machine learning models for risk prediction, addressing complex patient phenotypes and interactions. Discontinuation vs. continuation of renin–angiotensin system inhibition before non-cardiac surgery: the SPACE trial has challenged existing practices regarding the discontinuation of ACE inhibitors or ARBs, highlighting the dynamic nature of medical guidelines and the continuous incorporation of new evidence to enhance patient care.

Presented by Andy Cumpstey and Joff Lacey with Mark Edwards, Consultant in Anaesthesia and Perioperative Medicine, University Hospital Southampton Honorary Senior Clinical Lecturer, University of Southampton and John Whittle, Clinical Academic working in Perioperative Translational Medicine at UCL and Honorary Consultant in Perioperative Medicine, Anaesthesia and Critical Care at University College Hospitals London.

More on POISE-3 here: https://clinicaltrials.gov/study/NCT03505723

More on OPTIMISE II here: https://optimiseii.org/

More on the SPACE trial here: https://doi.org/10.1093/eurheartj/ehad716

TopMedTalk talks to Sam Azijian | TMT at EA24 Aug 26, 2024

Show notes

Euroanaesthesia is one of the most important and inﬂuential annual congresses in anaesthesiology and intensive care. This year, TopMedTalk was there in Munich, Germany, bringing you exclusive coverage.

In this piece we find out how laryngoscopy has moved forward, where AI might take us and why sustainability important in medicine.

Presented by Desiree Chappell with Sam Azijian, Chief Medical Officer, Acute Care & Monitoring, Medtronic.

Perioperative medicine in focus | EBPOM 24 Aug 19, 2024

Show notes

This episode underscores the evolution of perioperative medicine, the importance of innovation, teamwork, and data. The conversation reflects on past achievements and looks forward to future advancements in medical care. Our guest, a seasoned medical professional with a 40-year career, reflects on his journey from a young doctor in London to a consultant in Sydney. His plenary session at the Evidence Based Perioperative Medicine (EBPOM) congress highlighted key experiences and innovations in his career.

Presented by Andy Cumpstey with Ross Kerridge, Senior Staff Anaesthetist at the John Hunter Hospital, Newcastle, Australia and Associate Professor at the University of Newcastle.

Is Trauma Informed Care part of your perioperative process? | TopMedTalk Aug 12, 2024

Show notes

In this piece our guest shares her journey from general anesthesiology to focusing exclusively on obstetrics, driven by her training as a sexual assault counselor. She highlights the prevalence of trauma among patients and the need for trauma-informed care practices.

Presented by Desiree Chappell with her guest Tracey Vogel, Obstetric Anesthesiologist, Allegheny Health Network and Founder of The Empowerment Equation, LLC.

More here: https://www.theempowermentequation.com/

Talks to... Bruce Biccard | Prato 2024 Aug 05, 2024

Show notes

More from our coverage of the 7th Collaborative Clinical Trials in Anaesthesiology Conference, Prato, Italy.

The South African Perioperative Research Group (SAPORG) is a multidisciplinary group of researchers interested in improving perioperative outcomes in South Africa, through collaborative research

Presented by Monty Mythen and Desiree Chappell with their guest Bruce Biccard, Professor and Second Chair at Groote Schuur Hospital and University of Cape Town, Chair of the South African Perioperative Research Group (SAPORG).

Bruce's book is here: https://www.amazon.co.uk/Safer-Surgery-Africa-Challenges-Solutions/dp/0796153116

Earth Cast is here: https://podcasts.apple.com/gb/podcast/earth-cast/id1548400137

Freedom Challenge is here: https://www.freedomchallenge.org.za/

The Protect Platform trial | Prato 2024 Jul 29, 2024

Show notes

More from our coverage of the 7th Collaborative Clinical Trials in Anaesthesiology Conference, Prato, Italy.

This piece discusses trials in the wake of COVID-19 specifically we focus upon the PROTECT Platform Trial.

Presented by Monty Mythen and Kate Leslie with their guests Tom Abbott, anaesthetist and clinical lecturer at Queen Mary University of London and James Glasbey, NIHR Academic Clinical Lecturer in Global Surgery, University of Birmingham and General Surgery Registrar.

The DanGer Shock Trail | EBPOM World Congress 2024 Jul 26, 2024

Show notes

This piece looks at the DanGer Shock Trial which examines the efficacy of the Impella device in reducing mortality in patients with acute myocardial infarction and cardiogenic shock. We explain how the device works, its implantation process, and the significant findings from the trial, including a notable reduction in six-month mortality with a number needed to treat (NNT) of eight. Despite higher rates of bleeding and renal filtration therapy in the Impella group, the trial provides strong evidence supporting its use in high-volume centers with trained personnel, emphasizing the importance of careful patient selection and timely intervention.

Presented by Andy Cumpstey and Joff Lacey with their guest Vasileios Panoulas, an interventional cardiologist at Brompton and Harefield Hospitals and an honorary senior clinical lecturer at Imperial College London.

Innovation and leadership in anaesthesia | Euroanesthesia 2024 Jul 22, 2024

Show notes

This year TopMedTalk were at Euroanesthesia 2024, Munich, Germany.

In this piece we discuss anesthesia leadership, sustainability in healthcare, and innovations like Portrait Mobile and low-flow anesthesia. Our guest also shares her personal story as an immigrant and woman in industry, emphasizing the importance of mentorship, sponsorship, and balancing one's personal and professional life.

Presented by Desiree Chappell and Kate Leslie with their guest Alla K. Woodson, Global GM, Anesthesia, Respiratory Care, and PCS Services, GE Healthcare.

TRACTION trial and the B-Free trial in focus | Prato 2024 Jul 15, 2024

Show notes

This conversation was recorded at The 7th Collaborative Clinical Trials in Anaesthesiology Conference, Prato, Italy.

This piece focuses upon the TRACTION trial and the B-Free trial.

The TRACTION trial is here: https://tractiontrials.org/

The B-Free trial is here: https://www.phri.ca/research/b-free/

Desiree Chappell and Andy Cumpstey speak with their guests Jessica Spence, Assistant Professor at McMaster University and the Principal Investigator of the B-Free Cluster Crossover Trial and Ryan Zarychanski Professor of internal medicine at the Max Rady College of Medicine, Hematologist, critical care physician and clinician-scientist at the University of Manitoba and CancerCare Manitoba.

Equity, decolonisation and medical research | Prato 2024 Jul 08, 2024

Show notes

The team bring us more interviews from The 7th Collaborative Clinical Trials in Anaesthesiology Conference, Prato, Italy.

This piece focuses upon the importance of global and equitable research partnerships, highlighting guidelines like TDR's Essence and the Trust Code. The conversation also touches on the need to decolonize health research and the necessity of systemic changes to support women in science and medicine.

Presented by Desiree Chappell, Kate Leslie and Mike Grocott with their guest Jocelyn Clark, the international editor of BMJ.

Four Approaches to Supporting Equitable Research Partnerships:

https://tdr.who.int/docs/librariesprovider10/essence/four-approaches-to-supporting-erps.pdf?sfvrsn=c3aa83ea_12

The Trust Code:

https://www.globalcodeofconduct.org/

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