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    Life Sciences

    Tiny Matters

    Science shapes every facet of our lives, but so much of its influence is overlooked or buried in the past. Tiny Matters is an award-winning science podcast about the small science of big things. From the microbes behind deadly diseases to the molecules informing our search for extraterrestrial life, hosts and former scientists Sam Jones and Deboki Chakravarti embrace the awe and messiness of science and its significance both today and in the past, asking questions like, “how was IVF invented?,” “what do glaciers tell us about Earth’s ancient past?,” and “why is smallpox the only human infectious disease we’ve eradicated?”

    Tiny Matters is created by the American Chemical Society, a non-profit scientific organization based in Washington, D.C., and is produced by Multitude. New episodes every Wednesday, wherever you listen to podcasts.

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    Copyright: © 2025 American Chemical Society

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    Latest Episodes:
    Making labs safer: A heavy metal poisoning, a deadly protein exposure, and their aftermath Jul 09, 2025
    Show notes

    In January, 1997, David Nierenberg was a physician at Dartmouth‐Hitchcock Medical Center, specializing in toxicology. Chemist Karen Wetterhahn was placed in his care. When she arrived at the hospital, Karen was slurring her speech and having difficulty balancing and with coordination. What David soon learned was that her symptoms were all due to a few tiny drops of a compound called dimethylmercury. Today’s episode focuses on two lab accidents that had a profound impact on research communities, and that inspired changes that have likely saved the lives of scientists and other workers since. The first story is that of Karen Wetterhahn who, in the 1990s was a professor of chemistry at Dartmouth College whose lab focused on heavy metal toxicity. The other story is about fatal prion protein exposures in France that led to a temporary moratorium in 2021.

    Send us your science facts, news, or other stories fora chance to be featured on an upcoming Tiny Show and Tell Us bonus episode. And, while you're at it, subscribe to our newsletter!

    Links to the Tiny Show and Tell stories are here and here. All Tiny Matters transcripts and references are available here.

    See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.


    [BONUS] Fetuses ‘listening’ to different languages and climate change affecting psychiatric meds: Tiny Show and Tell Us #26 Jul 02, 2025
    Show notes

    In this episode of Tiny Show and Tell Us, we talk about how climate change may impact the effectiveness of mental health medications and how heat waves impact mental health more generally. Then we cover how fetal heart rates can change depending on which language they’re hearing while in the womb.

    We need your stories — they're what make these bonus episodes possible! Write in to tinymatters@acs.org *or fill out this form* with your favorite science fact or science news story for a chance to be featured.

    A transcript and references for this episode can be found at acs.org/tinymatters.

    See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.


    How NASA scientists are monitoring and predicting wildfires from space Jun 25, 2025
    Show notes

    Climate change has brought forth extreme fire events, like the Palisade and Eaton fires in Los Angeles, which devastated communities in Altadena and the Pacific Palisades in the beginning of 2025. And it’s becoming harder to not wonder: Is this just the world we live in now? Under the constant threat of catastrophic fires? Fortunately, we have the perfect guests to answer that question. We traveled to NASA’s Goddard Space Flight Center and spoke with two of their scientists who study fires from space.

    Send us your science facts, news, or other stories fora chance to be featured on an upcoming Tiny Show and Tell Us bonus episode. And, while you're at it, subscribe to our newsletter!

    Links to the Tiny Show and Tell stories are here and here. All Tiny Matters transcripts and references are available here.

    See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.


    [BONUS] The FDA’s ban of Red Dye No. 3 and the surprising science of winter roads: Tiny Show and Tell Us #25 Jun 18, 2025
    Show notes

    In this episode of Tiny Show and Tell Us, we talk about why the FDA recently banned Red Dye No. 3 and how concerned people should be about its use in food. Then we cover icy winter roads and the fascinating science behind clearing them and taking a more sustainable approach that won’t hurt the environment.

    We need your stories — they're what make these bonus episodes possible! Write in to tinymatters@acs.org *or fill out this form* with your favorite science fact or science news story for a chance to be featured.

    A transcript and references for this episode can be found at acs.org/tinymatters.

    See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.


    How a Mars mission from the 1970s shaped the search for extraterrestrial life today Jun 11, 2025
    Show notes

    In 1975, NASA launched two spacecraft to Mars. Viking 1 and Viking 2 arrived at their destination less than a year later, each bringing a lander to explore the surface of the planet and an orbiter to survey above. What was supposed to be a 90 day mission ended up lasting until the early 1980s. Those years provided scientists with important data about the Martian landscape, from seismometer readings of marsquakes to the reddish color of the sky.

    But the Viking missions had another important task: they were going to look for possible signs of life. The Viking experiments would go on to become an important landmark in science, one that’s helped researchers in a number of fields figure out what we can be doing better to find signs of life beyond Earth.

    Send us your science facts, news, or other stories fora chance to be featured on an upcoming Tiny Show and Tell Us bonus episode. And, while you're at it, subscribe to our newsletter!

    Link to the Tiny Show and Tell story is here. All Tiny Matters transcripts and references are available here.

    See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.


    [BONUS] Babies leaving cells behind in mom and rethinking the Big Bang: Tiny Show and Tell Us #24 Jun 04, 2025
    Show notes

    In this episode of Tiny Show and Tell Us, we talk about what dark energy and dark matter are made out of and how knowing more could upend our understanding of the Big Bang. Then we cover microchimeric cells — cells transferred between baby and mom — and how new research in mice shows that fetal cells that took residency in mom from a first pregnancy are replaced by new fetal cells of a second pregnancy.

    We need your stories — they're what make these bonus episodes possible! Write in to tinymatters@acs.org *or fill out this form* with your favorite science fact or science news story for a chance to be featured.

    A transcript and references for this episode can be found at acs.org/tinymatters.

    See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.


    Ozempic: The science behind this blockbuster drug and its untapped potential May 28, 2025
    Show notes

    In December 2017, the FDA approved a new injectable drug to treat type 2 diabetes called semaglutide, which you likely know by its brand name: Ozempic. A few years later, during the pandemic, Wegovy, a drug with a higher dose of the same active ingredient, was approved specifically for chronic weight management. Soon after, people taking Ozempic started reporting a dramatic, even “life-changing” weight loss. Ozempic is now a bona fide blockbuster. So what’s the science behind these “wonder drugs” that apparently 1 in 10 of us could end up using? They have the potential to have so many positive effects on our lives, from treating Alzheimer’s disease and addiction to changing our relationship with consumption but, like with most things, they also come with risks.

    Send us your science facts, news, or other stories fora chance to be featured on an upcoming Tiny Show and Tell Us bonus episode. And, while you're at it, subscribe to our newsletter!

    Links to the Tiny Show and Tell stories are here and here. All Tiny Matters transcripts and references are available here.

    See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.


    [BONUS] Marfan syndrome and plant pathogens eating DNA: Tiny Show and Tell Us #23 May 21, 2025
    Show notes

    In this episode of Tiny Show and Tell Us, we hear from a listener who has Marfan syndrome and dive into the complexities of the disease. Then we talk about pathogens that eat — or infiltrate! — plant DNA.

    We need your stories — they're what make these bonus episodes possible! Write in to tinymatters@acs.org *or fill out this form* with your favorite science fact or science news story for a chance to be featured.

    A transcript and references for this episode can be found at acs.org/tinymatters.

    See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.


    How a little-known vaccine project and decades of HIV research made "Operation Warp Speed" possible May 14, 2025
    Show notes

    Over the last 200 years or so, vaccines have come a long way, for a number of viruses. We’ve made so much progress, in fact, that in 2017 scientists began the early stages of vaccine development for some virus families they believed could pose a future pandemic threat. One of those families was Coronaviridae: coronaviruses. Not many people know that before SARS-CoV-2 started making its way into people in 2019, there was already a project underway in the U.S. to create a vaccine for a looming coronavirus (we didn't!), but even that would not have been possible without the decades of vaccine and drug research that came before it, particularly for HIV.

    Send us your science facts, news, or other stories fora chance to be featured on an upcoming Tiny Show and Tell Us bonus episode. And, while you're at it, subscribe to our newsletter!

    Links to the Tiny Show and Tell stories are here and here. All Tiny Matters transcripts and references are available here.

    See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.


    [BONUS] Time limits for anesthesia and stunning bioluminescence: Tiny Show and Tell Us #22 May 07, 2025
    Show notes

    In this episode of Tiny Show and Tell Us, we break down what limits on anesthesia could mean, both for doctors and patients. Then we hear from a listener who’s on a research trip in Puerto Rico and went kayaking in a bioluminescent bay. What is bioluminescence? And what are the perfect conditions to try to see it?

    We need your stories — they're what make these bonus episodes possible! Write in to tinymatters@acs.org *or fill out this form* with your favorite science fact or science news story for a chance to be featured.

    A transcript and references for this episode can be found at acs.org/tinymatters.

    Check out this Journey to the Microcosmos video, "The Algae That Saved an Astronaut's Life"

    See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.


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