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    Life Sciences

    Tiny Matters

    Science shapes every facet of our lives, but so much of its influence is overlooked or buried in the past. Tiny Matters is an award-winning science podcast about the small science of big things. From the microbes behind deadly diseases to the molecules informing our search for extraterrestrial life, hosts and former scientists Sam Jones and Deboki Chakravarti embrace the awe and messiness of science and its significance both today and in the past, asking questions like, “how was IVF invented?,” “what do glaciers tell us about Earth’s ancient past?,” and “why is smallpox the only human infectious disease we’ve eradicated?”

    Tiny Matters is created by the American Chemical Society, a non-profit scientific organization based in Washington, D.C., and is produced by Multitude. New episodes every Wednesday, wherever you listen to podcasts.

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    Copyright: © 2025 American Chemical Society

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    Latest Episodes:
    [BONUS] The history of Turner Syndrome and engineering food for bees: Tiny Show and Tell Us #45 Apr 22, 2026
    Show notes

    In this episode of Tiny Show and Tell Us, we trace the history of Turner Syndrome — from early clinical observations to the discovery of its chromosomal cause — highlighting how scientists began connecting symptoms to genetics long before DNA was fully understood. Then we follow up on a listener note about lab safety by explaining, at a molecular level, why dimethylmercury and prions are so dangerous to the human body. Ending on something more hopeful, we explore new research showing how engineered yeast could help give honey bees the nutrients they need to thrive. Team bees!

    Check out American Medieval here or wherever you listen to podcasts!

    We need your stories — they're what make these bonus episodes possible! Write in to tinymatters@acs.org *or fill out this form* with your favorite science fact or science news story for a chance to be featured.

    A transcript and references for this episode can be found at acs.org/tinymatters.

    See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.


    How soap shaped civilizations — and ‘ruined’ famous art Apr 15, 2026
    Show notes

    In the heart of The Hague, Netherlands, the museum Mauritshuis displays some of the world’s most iconic art in its Royal Cabinet of Paintings, including ones from Rembrandt and Vermeer’s Girl with a Pearl Earring. But there’s another oil painting by Vermeer that is also quite famous, called View of Delft — it's of his hometown, created around 1660.

    The painting is a cityscape — the only one Vermeer ever painted — a snapshot of the Dutch city of Delft from across the Schie River. In it you see the city’s beautiful architecture on full display, including buildings with striking red roofs. Well, at least they used to be red. Today they have a pink-ish hue and if you looked at the painting up close, you’d see that they are covered in white spots. And what may come as a surprise is that they are, in fact, soap. In today’s episode of Tiny Matters, we’re going to talk about the weird chemistry of soap, what ancient soap was like, and why scientists are finding soap in old oil paintings.

    Send us your science facts, news, or other stories for a chance to be featured on an upcoming Tiny Show and Tell Us bonus episode. And, while you're at it, subscribe to our newsletter!

    All Tiny Matters transcripts and references are available here.

    See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.


    [BONUS] Camel antibodies and colorful Greco-Roman statues: Tiny Show and Tell Us #44 Apr 08, 2026
    Show notes

    In this episode of Tiny Show and Tell Us, we explore the strange world of camelid antibodies—tiny, heavy-chain-only immune molecules that turned out to be incredibly useful for research and medicine. Then we chat about archaeochemistry and how pristine white Greco-Roman statues were once "garishly" painted. Using modern chemical techniques, scientists are revealing traces of vivid pigments like Egyptian blue. But how definitive are these reconstructions? Drama!

    Check out Wow if True here or wherever you listen to podcasts!

    We need your stories — they're what make these bonus episodes possible! Write in to tinymatters@acs.org *or fill out this form* with your favorite science fact or science news story for a chance to be featured.

    A transcript and references for this episode can be found at acs.org/tinymatters.

    See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.


    Stinky white gold, Haber-Bosch, and ‘peecycling’: How fertilizer shapes our world Apr 01, 2026
    Show notes

    Fertilizer… boring? Not on our watch! In this episode of Tiny Matters, we trace the history of fertilizer from the ‘Guano Wars’ to the invention of the Haber-Bosch process, one of the most impactful chemical breakthroughs in human history. Today, scientists and communities are rethinking how we handle nutrients, and asking: could our own urine help close the nutrient loop? We chat with chemist Leila Duman about why nitrogen is so hard to “fix,” how industrial fertilizer feeds billions (while unfortunately polluting waterways), and why the Haber-Bosch process is still essentially perfect. Then we head to Vermont’s Rich Earth Institute, where researchers are turning human urine into safe, effective fertilizer and reimagining waste as a resource.

    Check out Pale Blue pod!

    Send us your science facts, news, or other stories for a chance to be featured on an upcoming Tiny Show and Tell Us bonus episode. And, while you're at it, subscribe to our newsletter!

    All Tiny Matters transcripts and references are available here.

    See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.


    [BONUS] Reef balls and peanut allergy immunotherapy: Tiny Show and Tell Us #43 Mar 25, 2026
    Show notes

    In this episode of Tiny Show and Tell Us, we explore a listener's experience with peanut allergy immunotherapy — what it is, how the therapy works, and the odd and fascinating history of allergy treatments, including a 19th‑century scientist who shoved grass pollen up his own nose. Then we chat about “reef balls” made of oyster shells and concrete. These mini artificial reefs are being used to restore marine habitats and, in some cases, also hold cremated remains.

    Check out Simple and Clean here or wherever you listen to podcasts!

    We need your stories — they're what make these bonus episodes possible! Write in to tinymatters@acs.org *or fill out this form* with your favorite science fact or science news story for a chance to be featured.

    A transcript and references for this episode can be found at acs.org/tinymatters.

    See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.


    The Mothers of Gynecology: The centuries that led to today’s Black maternal mortality crisis Mar 18, 2026
    Show notes

    In this special crossover episode, Tiny Matters welcomes Alexis Pedrick, host of Distillations from the Science History Institute. You’ll hear the Distillations episode “The Mothers of Gynecology” — a powerful investigation into the racist origins of gynecology and the ongoing maternal health care crisis that disproportionately affects Black mothers. Through interviews with historians, clinicians, midwives, doulas, and public health researchers, the episode traces how racist myths about Black bodies — especially beliefs about pain tolerance — continue to shape medical care and outcomes. Following the episode, we unpack some of what you’ll hear, from the horrific exploitation of enslaved women by J. Marion Sims, to modern-day disparities that affect even the wealthiest, most famous Black mothers, including Beyoncé and Serena Williams.

    Check out Spirits here or wherever you listen to podcasts.

    Send us your science facts, news, or other stories for a chance to be featured on an upcoming Tiny Show and Tell Us bonus episode. And, while you're at it, subscribe to our newsletter!

    All Tiny Matters transcripts and references are available here.

    See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.


    A new podcast joining the fam: Chain Reaction by ACS! Mar 13, 2026
    Show notes

    Chain Reaction is a new podcast from the American Chemical Society that links chemistry’s past to its future, revealing how this ever‑evolving science shapes the world around us, from the materials we use every day to the environment that we depend on. Each episode brings fresh perspectives and personal stories from chemists, engineers, and other scientists, as well as historians who guide us through pivotal moments in chemistry’s history. Together, we’ll uncover chemistry’s surprising connections, explore its interdisciplinary impact, and see how past discoveries set off the breakthroughs of today and the future.

    Whether you’re a student, an experienced scientist, or simply curious, Chain Reaction will show you how chemistry fits into the bigger picture — and why it matters now more than ever. Subscribe wherever you listen to podcasts! acs.org/chainreaction

    Exec producer: Sam Jones

    Producer: Margot Wohl

    Researcher: Bec Roldan

    Production support: Michael David and Matthew Radcliff

    Cover art: Joe Butera

    See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.


    [BONUS] 5D storage in the ‘Memory of Mankind’ and the root of morning sickness: Tiny Show and Tell Us #42 Mar 11, 2026
    Show notes

    In this episode of Tiny Show and Tell Us, we go from nerdy house-party physics to the brutal realities of morning sickness (can you say range!). First, we unpack what 5D data storage is and debate what we’d personally toss into the “Memory of Mankind” salt mine in Austria. Then we tackle a listener’s question about whether science has any updates on what causes severe morning sickness.

    We need your stories — they're what make these bonus episodes possible! Write in to tinymatters@acs.org *or fill out this form* with your favorite science fact or science news story for a chance to be featured.

    A transcript and references for this episode can be found at acs.org/tinymatters.

    See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.


    Inside expedition medicine: Keeping people alive in the harshest places on Earth Mar 04, 2026
    Show notes

    In 2019, Nathan Hudson-Peacock was serving as an expedition doctor to a group hiking in the Indian Himalayas. At around 17,000 feet, a climber suddenly went from having a mild headache to a life‑threatening cerebral edema. On top of that, a storm was closing in. So, what did he do? How do expedition doctors keep people alive in the harshest places on Earth? Tune in to this week’s episode to find out. In it, we chat with Nathan as well as high altitude physician Monica Piris, who has spent much of her time on Everest. We dig into the world of expedition medicine: the preparation, the danger, the breathtaking environments, and the moments that can reshape your understanding of the planet and the impact of climate change.

    Listen to American Medieval: https://americanmedieval.com/

    Send us your science facts, news, or other stories for a chance to be featured on an upcoming Tiny Show and Tell Us bonus episode. And, while you're at it, subscribe to our newsletter!

    All Tiny Matters transcripts and references are available here.


    See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.


    [BONUS] 'Mitochondrial Eve' and birds stealing anti-bird spikes: Tiny Show and Tell Us #41 Feb 25, 2026
    Show notes

    In this episode of Tiny Show and Tell Us, we talk about the crafty corvids that steal anti‑bird spikes to build chaotic, spiky nests and “Mitochondrial Eve” — the most recent common maternal ancestor of modern humans. Get ready for stories of sandwich‑stealing gulls, Deboki being held hostage by a peacock, and the Mitochondrial Eve/Y Chromosomal Adam romcom no one asked for.

    We need your stories — they're what make these bonus episodes possible! Write in to tinymatters@acs.org *or fill out this form* with your favorite science fact or science news story for a chance to be featured.

    A transcript and references for this episode can be found at acs.org/tinymatters.

    See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.


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