This Week in Virology

Latest Episodes:

TWiV #102 - Catch me if you can in Munich Oct 11, 2010

Show notes

A conversation about the RNA sensor RIG-I, adenovirus gene therapy, a universal influenza vaccine, and rabies virus, recorded in Munich, Germany at the SFB455 symposium ‘Viral offense and immune defense’.

TWiV #101 - Sizing up adenovirus Oct 03, 2010

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Vincent, Alan, Rich, Dickson, and Hamish review the three-dimensional structure of adenovirus, and the role of adenovirus type 36 in obesity.

TWiV #100 - TWiV catches a big fish Sep 26, 2010

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Vincent, Alan, and Rich celebrate the 100th episode of TWiV by talking about viruses with Nobel Laureate David Baltimore.

TWiV #99 - ICAAC Boston 2010 Sep 20, 2010

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On episode #99 of the podcast This Week in Virology, Vincent tours the 50th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), speaking with exhibitors and visitors, including Professors Derek Smith, Michael Schmidt, Frederick Hayden, and Myra McClure.

Host links Vincent Racaniello

Links for this episode:

50th ICAAC
ICAAC daily press conference videos (including Prof. Myra McClure)
Antigenic cartography
Antimicrobial properties of copper

TWiV #98 - Murine musings, electric shirts, and rabid pathologists Sep 13, 2010

Show notes

On episode #98 of the podcast This Week in Virology, Vincent, Alan, and Rich review the finding of murine leukemia virus-related sequences in the blood of CFS patients and healthy donors, laboratory inventories for wild poliovirus containment, weaving high-performance viral batteries into fabric for the military, and a case of human rabies in Indiana.

TWiV #97 - California virology Sep 06, 2010

Show notes

On episode #97 of the podcast This Week in Virology, Vincent visited Peter Sarnow and Bert Semler during a trip to California, and spoke with them about their work on internal ribosome entry, and the requirement for a cellular microRNA for hepatitis C virus replication.

TWiV #96 - Making viral DNA Aug 22, 2010

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On episode #96 of the podcast This Week in Virology, Vincent, Dickson, and Rich continue Virology 101 with a discussion of how viruses with DNA genomes replicate their genetic information.

TWiV #95 - Does a virus shift in the woods? Aug 15, 2010

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On episode #95 of the podcast This Week in Virology, Vincent, Dickson, Alan, and Rich consider the end of the influenza H1N1 pandemic, dengue in Florida, vaccinia virus infection in Brazilian monkeys, and viruses in the faecal microbiota.

Host links Vincent Racaniello, Dickson Despommier, Alan Dove, and Rich Condit

Links for this episode:

WHO declares end of influenza H1N1 pandemic
CDC's FluView
WHO global monitoring of influenza
Locally acquired dengue in Key West, Florida (MMWR)
CDC page on dengue
Vaccinia virus infection in monkeys of the Brazilian Amazon
Dam site where animals were collected for vaccinia study (Google maps)
Rich's article: Whence feral vaccinia?
Viruses in the faecal microbiota of monozygotic twins and their Mothers (Nature)
New Yorker article The Treatment (thanks, Jim!)
Letters read on TWiV 95

Weekly science picks:

Alan - Families Fighting Flu Rich - Food, Inc. Dickson - Fuel Vincent - MIT Open Courseware Michael - Waiting for Superman and Can Science Feed the World? (Nature)

TWiV #94 - XMRV with Dr. Ila Singh Aug 08, 2010

Show notes

On episode #94 of the podcast This Week in Virology, Vincent, Alan, and Rich speak with Ila Singh about the new human retrovirus XMRV, and how her laboratory is studying its association with prostate cancer and chronic fatigue syndrome.

Host links Vincent Racaniello, Alan Dove, Rich Condit, and Ila Singh

Links for this episode:

CFIDS Association of America
Discovery of XMRV (PLoS Pathogens)
Detection of XMRV in CFS patients (Science)
Presence of XMRV in malignant prostate (PNAS)
Inhibition of XMRV by raltegravir (PLoS One)
Letters read on TWiV 94

Weekly science picks:

Alan - The new Federal Register site (see also regulations.gov) Rich - The Florida Museum of Nautural History Butterfly Rainforest Vincent - JoVE, the Journal of Visualized Experiments

TWiV #93 - Our infectious inbox Aug 01, 2010

Show notes

On episode #93 of the podcast This Week in Virology, Vincent, Alan, and Rich answer listener questions about lab procedures, prokaryotes, endogenous retroviruses, the iPad and teaching, prions, mimivirus, splitting water with viruses, and the polio outbreak in Tajikistan.

Host links Vincent Racaniello, Alan Dove, and Rich Condit

Links for this episode:

Biomedical Advanced Research and Development Authority (BARDA)
SIGA responds to BARDA request for smallpox antiviral
BARDA contract for filovirus vaccine
What is a Ph.D? (pdf)
HHMI resources for early career scientists
Pace article on abandoning prokaryote (Nature)
Three domains of life (Forterre article)
Mechanoenzymatic cleavage of Von Willebrand's factor (Science)
Splitting water with viruses
WHO coverage on Tajikstan polio outbreak
Wild type polio infection in immunized Indian children (JID)
Letters read on TWiV 93

Weekly science picks:

Alan - Southern Fried Science Rich - Tree of Life web project Vincent - Dickson Despommier at Big Think

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