This Week in Virology

Latest Episodes:

TWiV 240: Virology in Vermont Jul 03, 2013

Show notes

Vincent travels to the University of Vermont to talk with Markus and Jason about their work on HIV, influenza virus, arenaviruses and hantaviruses.

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TWiV 239: Filterable camels Jun 29, 2013

Show notes

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Matt Frieman

Matt joins Vincent, Alan, and Rich to summarize what we know and what we do not know about the MERS coronavirus.

Links for this episode:

MERS-CoV update (WHO)
MERS-CoV evolution (epidemic)
Sick camel linked to MERS-CoV death (7Days)
MERS-CoV hospital outbreak (NEJM)
MERS-CoV French hospital cluster (Lancet)
MERS-CoV family cluster (NEJM)
Matt on MERS-CoV on the Voice of Russia
Letters read on TWiV 239

Weekly Science Picks

Matt - The Kid Should See ThisAlan - Cassini to photograph Earth Vincent -Cockroaches! (YouTube)Rich - Sydney Brenner (Web of Stories)

Listener Pick of the Week

Ebrahim - Virus Hunter by CJ Peters and Mark Olshaker

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TWiV 238: Lost in translation Jun 23, 2013

Show notes

Hosts: Vincent Racaniello, Rich Condit, and Kathy Spindler

Vincent, Rich and Kathy discuss mechanisms of protein synthesis and regulation in virus-infected cells.

Links for this episode:

Slides for this episode (pdf)
T7 ribosomal binding sites (CSH Symp Quant Biol)
Tinkering with translation (CSH Persp)
Translation at nexus of infection and immunity (Cell Host Microbe)
Viral subversion of protein synthesis machinery (Nat Rev Micr)

Weekly Science Picks

Kathy - Vaccine-preventable outbreaks Rich - To Catch a Virus by John Booss and Marilyn J. AugustVincent - This is Water by David Foster Wallace

Listener Pick of the Week

Jon - Confessions of a converted lecturer by Eric MazurPeter - FameLab

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TWiV 237: Paleovirology with Michael Emerman Jun 16, 2013

Show notes

Hosts: Vincent Racaniello and Rich Condit

Guest: Michael Emerman

Vincent and Rich recorded this episode at the Fred Hutchinson Cancer Research Center in Seattle, WA, where they met up with Michael to talk about his work on the molecular and evolutionary basis of HIV replication and pathogenesis.

Links for this episode:

Ancient origins of SIV (PLoS Path)
Paleovirology (PLoS Biology)
Harmit Malik on TWiV 205
Sara Sawyer on TWiV 193

Listener Pick of the Week

Molly - Facts in the case of Dr. Andrew Wakefield

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

TWIV 236: Flu gets the VIP treatment Jun 09, 2013

Show notes

Hosts: Vincent Racaniello, Alan Dove, and Kathy Spindler

Vincent, Alan and Kathy review novel approaches to preventing influenza virus infection.

Links for this episode:

Ultraprotective influenza vaccine in mice (PNAS)
Vectored immunoprophylaxis of influenza in mice (Nat Biotech)
Intranasal antibody gene transfer protects agains influenza (Sci Transl Med)
Estimating influenza associated deaths (CDC)
Multistate HAV outbreak (CDC)
Subscribe to Microbeworld video (YouTube)
Save podcasting (EFF)
Letters read on TWiV 236

Weekly Science Picks

Alan - Psychology of antivaccinationists Vincent - Virology on CourseraKathy - Meteorites through the ages

Listener Pick of the Week

Basel - Self-medication in animalsSheryl - Noadi's artFelicity - Survival of the Sickest by Sharon Moalem

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TWiV 235: Live in Edmonton, eh? Jun 03, 2013

Show notes

Hosts: Vincent Racaniello and Rich Condit

Guests: Dave Evans, Stan Lemon, and Lorne Tyrrell

Vincent and Rich recorded this episode before an audience at the 2nd Li Ka Shing Institute of Virology Symposium at the University of Alberta, where they spoke with Dave, Stan, and Lorne about their work on poxvirus vaccines and recombination, an enveloped picornavirus, antivirals against hepatitis B and C viruses, and supporting virology research in Alberta.

Links for this episode:

Li Ka Shing Institute of Virology
Alberta Heritage Foundation for Medical Research
Raised on a farm (YouTube)
Vaccinia virus strains in Dryvax vaccine (J Virol)
Vaccinia DNA polymerase and recombination (J Virol)
Picornavirus hijacks cell membrane (Nature)

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

TWiV 234: Live in Denver May 26, 2013

Show notes

Hosts: Vincent Racaniello and Kathy Spindler

Guests: Nels Elde and Tom Shenk

Vincent and Kathy recorded this episode before an audience at the 2013 General Meeting of the American Society for Microbiology in Denver, Colorado, where they spoke with Nels and Tom about their work on the evolution of virus-host conflict and how viruses influence the cell metabolome.

Links for this episode:

A cross-species view on viruses (Curr Op Virol)
Pox has got a squeeze box (TWiV 198)
Saturated fatty acids needed for CMV (PLoS Path)
CMV and HSV metabolomes differ (PLoS Path)
Video of this episode - view at YouTube

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

TWiV 233: We're surrounded May 18, 2013

Show notes

Hosts: Vincent Racaniello, Rich Condit, Alan Dove, and Kathy Spindler

Vincent, Rich, Alan and Kathy review aerosol transmission studies of influenza H1N1 x H5N1 reassortants, H7N9 infections in China, and the MERS coronavirus.

Links for this episode:

Aerosol transmission of H1N1 x H5N1 reassortants (Science)
It's good science (virology blog)
Viral engineering dangers (Nature)
Colorblind web page filter
Influenza H7N9 update (ProMedMail)
Influenza H7N9 risk assessment (WHO, pdf)
Influenza H7N9 confirmed cases (WHO)
New coronavirus gets a new name (ScienceInsider)
Novel coronavirus infection update (WHO)
Coronavirus infections (WHO)
Letters read on TWiV 233

Weekly Science Picks

Alan - Space Oddity (YouTube)Rich - Walk through giant colon Vincent - Transport proteinsKathy - Vomiting Larry (YouTube)

Listener Pick of the Week

Tom - US patent system is broken (DailyTech)

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

TWiV 232: Gophers go viral May 12, 2013

Show notes

Hosts: Vincent Racaniello, Roberto Cattaneo, Reuben Harris, Lou Mansky, and Leslie Schiff

Vincent meets up with Roberto, Reuben, Lou, and Leslie at the University of Minnesota to talk about their work on HIV-1, APOBEC proteins, measles virus, and teaching virology to undergraduates.

Links for this episode: