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    Life Sciences

    This Week in Microbiology

    This Week in Microbiology is a podcast about unseen life on Earth hosted by Vincent Racaniello and friends. Following in the path of his successful shows ‘This Week in Virology’ (TWiV) and ‘This Week in Parasitism’ (TWiP), Racaniello and guests produce an informal yet informative conversation about microbes which is accessible to everyone, no matter what their science background.

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    Copyright: © Creative Commons Attribution - Noncommercial

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    Latest Episodes:
    TWiM #137: The battle for oxygen Oct 20, 2016
    Show notes

    Highlights of the Recent Advances in Microbial Control meeting in San Diego, and expansion of a gut pathogen by virulence factors that stimulate aerobic respiration.

    Hosts: Vincent Racaniello, Elio Schaechter, Michael Schmidt, and Michele Swanson.

    Subscribe to TWiM (free) on iTunes, Stitcher, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

    Links for this episode
    • Fred Neidhardt obituary
    • Recent Advances in Microbial Control
    • Science hero Bill Fenical
    • Virulence factors and aerobic respiration (Science)
    • Image credit
    • Letters read on TWiM 137

    This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/m​icrobe ​and use the promo code MICROBE​.

    This episode is also brought to you by Drobo, a family of safe, expandable, yet simple to use storage arrays. Drobos are designed to protect your important data forever. Visit www.drobo.com to learn more. Listeners can save $100 on a Drobo system at drobostore.com by using the discount code Microbe100.

    Send your microbiology questions and comments (email or mp3 file) to twim@microbe.tv

    TWiM #136: Diderms and then monoderms Oct 07, 2016
    Show notes

    Them TWiM team discusses the importance of neutrophils in microbial infections, and evidence that ancient bacteria had two cell walls.

    Hosts: Vincent Racaniello, Elio Schaechter, Michael Schmidt, and Michele Swanson.

    Subscribe to TWiM (free) on iTunes, Stitcher, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

    Links for this episode
    • Conquering neutrophils (PLoS Path)
    • Ancestral outer membrane in firmicutes (eLife )
    • Were gram positive rods the first bacteria? (Cell)
    • Image credit
    • Letters read on TWiM 136

    This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/m​icrobe ​and use the promo code MICROBE​.

    This episode is also brought to you by Drobo, a family of safe, expandable, yet simple to use storage arrays. Drobos are designed to protect your important data forever. Visit www.drobo.com to learn more. Listeners can save $100 on a Drobo system at drobostore.com by using the discount code Microbe100.

    Send your microbiology questions and comments (email or mp3 file) to twim@microbe.tv

    TWiM #135: Unruly individuals and their unruly friends Sep 23, 2016
    Show notes

    Links for this episode

    • Dysbiosis of microbiome in critical illness (mSphere)
    • Consequences of sewage spill into aquatic environment (App Env Mic)
    • EPA recreational water guidelines (pdf)
    • VRE following sewage spill (Outbreak Radio)
    • FAQ: Human microbiome
    • American gut project
    • British gut project
    • Rob Knight on human microbiome (TED)
    • Rob Knight on TWiM
    • Image credit
    • TWiM 135 Letters

    This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/m​icrobe ​and use the promo code MICROBE​.

    This episode is also brought to you by Drobo, a family of safe, expandable, yet simple to use storage arrays. Drobos are designed to protect your important data forever. Visit www.drobo.com to learn more. Listeners can save $100 on a Drobo system at drobostore.com by using the discount code Microbe100.

    Send your microbiology questions and comments (email or mp3 file) to twim@microbe.tv

    TWiM #134: Lipids that live forever Sep 08, 2016
    Show notes

    Design of a synchronously lysing bacterium for delivery of anti-tumor molecules in mice, and hopanoids, the lipids that live forever, brought to you by the four Microbies of TWiM.

    Hosts: Vincent Racaniello, Elio Schaechter, Michael Schmidt, and Michele Swanson.

    Subscribe to TWiM (free) on iTunes, Stitcher, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

    Links for this episode
    • Bacterial lysis for in vivo delivery (Nature)
    • Coley's toxins (Iowa Orthop J)
    • Hopanoids, stress tolerance, and nutrient storage (Geobiol)
    • Lipids that last forever (STC)
    • Fattening up microbial geological biomarkers (STC)
    • Money spreads infection (Fut Micro)

    This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/m​icrobe ​and use the promo code MICROBE​.

    This episode is also brought to you by Drobo, a family of safe, expandable, yet simple to use storage arrays. Drobos are designed to protect your important data forever. Visit www.drobo.com to learn more. Listeners can save $100 on a Drobo system at drobostore.com by using the discount code Microbe100.

    Send your microbiology questions and comments (email or mp3 file) to twim@microbe.tv

    TWiM #133: Right under our noses Aug 20, 2016
    Show notes

    Insight into the biology of rhinovirus C from cryo-electron microscopy, and a novel antibiotic from a commensal bacterium that grows in the human nose, from the doctors of TWiM.

    Hosts: Vincent Racaniello, Elio Schaechter, and Michael Schmidt.

    Subscribe to TWiM (free) on iTunes, Stitcher, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

    Links for this episode
    • Cryo-EM of viruses and vaccine design (PNAS)
    • Atomic structure of rhinovirus C (PNAS)
    • Opening windows into the cell (STC)
    • Human commensals produce novel antibiotic (Nature)
    • The nose knows (Nature)
    • Letters read on TWiM 133

    Image in audio player: Molecular surface of a Human rhinovirus, showing protein spikes. By: Wiki user: Robin S

    This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/m​icrobe ​and use the promo code MICROBE​.

    This episode is also brought to you by Drobo, a family of safe, expandable, yet simple to use storage arrays. Drobos are designed to protect your important data forever. Visit www.drobo.com to learn more. Listeners can save $100 on a Drobo system at drobostore.com by using the discount code Microbe100.

    Send your microbiology questions and comments (email or mp3 file) to twim@microbe.tv

    TWiM #132: Bacteria learn long division Aug 05, 2016
    Show notes

    Vincent, Elio, and Michele present cell division by longitudinal scission in an insect symbiont, and thermally activated charge transport in microbial nanowires.

    Hosts: Vincent Racaniello, Michele Swanson and Elio Schaechter.

    Subscribe to TWiM (free) on iTunes, Stitcher, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

    Links for this episode
    • Cell division by longitudinal scission (mBio)
    • Bacterium learns long division (STC)
    • Charge transport by microbial nanowires (Sci Rep)
    • Mechanism of nanowire conductance (Nat Comm)
    • Using nature to grow batteries (TED)
    • SEM of Y-shaped S. poulsonii (above) - Image credit
    • Extracellular electron transport (below) - image credit

    This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/m​icrobe ​and use the promo code MICROBE​.

    This episode is also brought to you by Drobo, a family of safe, expandable, yet simple to use storage arrays. Drobos are designed to protect your important data forever. Visit www.drobo.com to learn more. Listeners can save $100 on a Drobo system at drobostore.com by using the discount code Microbe100.

    Send your microbiology questions and comments (email or mp3 file) to twim@microbe.tv

    TWiM 131: Mice behaving badly Jul 20, 2016
    Show notes

    Hosts: Vincent Racaniello and Michael Schmidt

    Michael and Vincent present Spotlights, brief reviews of classic papers in the Journal of Bacteriology, and explain how a single bacterial species can reverse autism-like social deficits in the offspring of obese mice.

    Links for this episode
    • Protein secretion in E. coli (J Bacteriol)
    • Plague pathogenesis (J Bacteriol)
    • Reversal of diet induced social defects (Cell)
    • Letters read on TWiM 131

    This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/microbe and use the promo code MICROBE.

    Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

    Send your microbiology questions and comments to twim@microbe.tv

    TWiM #130: Interkingdom interactions at ASM Microbe Jun 23, 2016
    Show notes

    Filmed live in Boston, MA at Microbe 2016, David S. Schneider and Vanessa Sperandio talk about their work on regulation of bacterial virulence in the gut by bacterial adrenergic sensors, and the physiological mechanisms that make us ill and that help us recover.

    TWiM #129: Dried and wrinkled, smooth and mucoid Jun 07, 2016
    Show notes

    The arrival in the US of plasmid-mediated resistance to colistin antibiotics, a last line of defense against many gram-negative bacilli, and a quorum sensing system in a eukaryote are topics of this episode hosted by Vincent, Michael, and Michele.

    Image: Etest used to determine the minimum inhibitory concentration of an antibiotic for a particular bacterium.

    Hosts: Vincent Racaniello, Michael Schmidt, and Michele Swanson.

    Subscribe to TWiM (free) on iTunes, Stitcher, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

    Links for this episode
    • E. coli with mcr-1 on a plasmid in the US (AAC)
    • Emergence of plasmid mediated colistin resistance in China (The Lancet)
    • Major breach in last line of defense (The Lancet)
    • Resistance plasmid families in Enterobacteriaceae (AAC)
    • EUCAST MIC breakpoints (ClinCalc)
    • Role of ASM in microbial resistance one, two (bLogphase)
    • Quorum sensing in fungi (Cell Host Microbe)
    • Image credit
    • Letters read on TWiM 129

    This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/m​icrobe ​and use the promo code MICROBE​.

    Send your microbiology questions and comments (email or mp3 file) to twim@microbe.tv

    TWiM #128: A moonlighting phage protein May 21, 2016
    Show notes

    A eukaryote without a mitochondrion, and using a phage enzyme to eliminate intracellular bacteria are two topics discussed by the TWiMers on this episode.

    Image (right): An entry in the ASM Agar Art Contest which bears an uncanny resemblance to one of the TWiM hosts.

    Hosts: Vincent Racaniello, Elio Schaechter, Michele Swanson, and Michael Schmidt.

    Subscribe to TWiM (free) on iTunes, Stitcher, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

    Links for this episode
    • Copper and Michael Schmidt in the news (The Scientist)
    • Fair Pay for Postdocs (Huff Post)
    • National Microbiome Initiative (White House)
    • The shrinking mitochondrion (The Scientist)
    • Eukaryote without a mitochondrion (Curr Biol)
    • Why have organelles retained genomes? (Cell Sys)
    • Bugs as drugs (Amer Acad Micro)
    • Phage encoded lysin eliminates intracellular bacteria (eLife)

    This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completel free if you sign up at curiositystream.com/m​icrobe ​and use the promo code MICROBE​.

    Send your microbiology questions and comments (email or mp3 file) to twim@microbe.tv

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