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    The Long Run with Luke Timmerman

    “The Long Run”

    Antarctic explorer Ernest Shackleton would appreciate today’s biotech. Scientific entrepreneurs of the 21st century must be ready for what Shackleton called the “hazardous journey, bitter cold, long months of complete darkness, constant danger, safe return doubtful, honor and recognition in case of success.” Today, the men and women who strive to apply science for the betterment of human health have a historic opportunity. They need stamina and resilience to achieve something meaningful. Biotech’s relationship with the society that sustains it has never been more tenuous.

    Join host Luke Timmerman for in-depth, thought-provoking conversations with biotech newsmakers pursuing these great opportunities of the 21st century.

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    Latest Episodes:
    Ep160: Abe Ceesay on Precision Neuroscience Jun 17, 2024
    Show notes

    Abe Ceesay, CEO of Boston-based Rapport Therapeutics, on a precision medicine approach to neuroscience drug discovery.


    Ep159: Jimi Olaghere on Being Functionally Cured of Sickle Cell Disease Jun 03, 2024
    Show notes

    Jimi Olaghere is one of the first patients to have been functionally cured of sickle cell disease with a CRISPR gene-edited cell therapy.


    Ep158: David Younger and Randolph Lopez on SynBio & AI for Discovery May 20, 2024
    Show notes

    David Younger and Randolph Lopez, co-founders of A-Alpha Bio, on using synthetic biology and AI to discover new biologic drugs.


    Ep157: Vineeta Agarwala of A16Z on Investing in AI for Drug Discovery May 01, 2024
    Show notes

    Vineeta Agarwala, general partner at A16Z's Bio & Health fund, on investing in AI for drug discovery.


    Ep156: David Liu on New Tools and Techniques for Biology Apr 16, 2024
    Show notes

    David Liu, professor of chemistry at Harvard University and co-founder of multiple biotech companies, including Beam Therapeutics and Prime Medicine.


    Ep155: Valerie Daggett on Early Detection, and Treatment, of Alzheimer's Mar 06, 2024
    Show notes

    Valerie Daggett, founder and CEO of Seattle-based AltPep, on early detection and treatment of Alzheimer's.


    Ep154: Robert Ang on CRISPR to Protect Bone Marrow & Attack Cancer Feb 09, 2024
    Show notes

    Robert Ang, CEO of Cambridge, Mass.-based Vor Bio, on using CRISPR gene editing to alter bone marrow transplants and improve treatment of acute myeloid leukemia.


    Ep153: Rick Young on Studying Gene Expression for Drug Discovery Jan 22, 2024
    Show notes

    Rick Young, professor at MIT and co-founder of Syros Pharmaceuticals, CAMP4 Therapeutics, Omega Therapeutics, and Dewpoint Therapeutics, on studying gene expression for drug discovery.


    Ep152: Jens Eckstein on Investing in Healthy Aging Jan 10, 2024
    Show notes

    Jens Eckstein, investment partner at Hevolution Foundation, on investing in healthy aging.


    Ep151: Shelley Force Aldred and Nathan Trinklein on Bispecific Antibodies for Cancer Dec 26, 2023
    Show notes

    Shelley Force Aldred and Nathan Trinklein, co-founders of Rondo Therapeutics, on the opportunity with bispecific antibodies for cancer.


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