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The Kris Gethin Podcast — Fitness & Nutrition
The Kris Gethin Podcast

Kris Gethin is widely known across the health and fitness space as one of the leading body transformation specialists in the world – he has been voted as the worlds #1 transformation coach and personal trainer on various platforms such as Trainerize and Bodybuilding.com and governing bodies such as PT Academy.

As the co-founder of the Kris Gethin Gyms franchise, co-founder of Unmatched Supplements, co-founder of NovaPrime Labs, founder of Biohacked AF, former editor-in-chief of BodyBuilding.com, former editor-at-large at Weider Publications and former publisher of Kaged Muscle magazine, Kris has helped educate and change the lives of millions of people. Kris is the host of The Kris Gethin Podcast and author of the best-selling book Body by Design. Kris has competed as a natural pro bodybuilder, IRONMAN Triathlete, Ultramarathoner, Spartan competitor and Motocross racer of 13 years.

He currently helps celebrities several months of the year, trains clients online year round via www.krisgethin.com and hosts anti-aging/fitness and biohacking seminars and retreats worldwide.

In this podcast, Kris dissects myths of muscle building and endurance, bridges the gap between health and sports supplementation, expands upon the healing benefits of smart nutrition, and strategies to change your perception for a happier, healthier and real way of life.

For more information check out https://www.krisgethin.com/

Latest Episodes:

229. The New GLP-1 Pill That Could Replace Injections Oct 16, 2025

Show notes

GLP-1s have dominated the headlines, but the next wave of compounds is already here, and they're changing the conversation on fat loss, performance, and longevity. In this episode, I break down the science behind four emerging therapies and why you need to know about them now.

We cover how Afoglipron, the first oral non-peptide GLP-1, removes the barrier of injections while delivering results on par with semaglutide. You'll hear why Teriparatide, originally used for osteoporosis, may reduce visceral fat and protect bone density at the same time. I also dive into Mazdutide, a dual GLP-1/glucagon agonist that suppresses appetite while boosting energy expenditure, and Tesofensine, a brain-targeting appetite suppressant with powerful effects on cravings.

I share what the latest clinical data shows, the benefits and risks for both general populations and athletes, and how these compounds could fit into the bigger picture of training, nutrition, and longevity.

This is a must-listen.

What's Discussed:

00:05 — Why GLP-1s have exploded and what's next beyond semaglutide

01:53 — Afoglipron: The first oral GLP-1 and why it's a game changer

07:16 — Teriparatide: Surprising fat loss potential in a bone health drug

10:29 — Mazdutide: The "eat less, burn more" dual agonist

13:17 — Tesofensine: Targeting food noise and cravings in the brain

16:20 — Are these drugs the future of fat loss, or a Pandora's box?

Thank you to our sponsors:

NAD + Cell Shield from Biostack Labs https://biostacklabs.com/kris

BiOptimizers - code KRIS10 for 10% off https://bioptimizers.com/

Timeline: My friends at Timeline are offering 20% off, just for my listeners. Head to timeline.com/GETHIN to get started.

LVLUP: Head over to LVLUPHealth.com and use code GETHIN at checkout to get 15% off.

Find more from Kris:

Website: https://www.krisgethin.com/

Instagram: @krisgethin

Youtube: https://www.youtube.com/krisgethin Unmatched Supplements: https://www.unmatchedsupps.com/

228. Glutathione: The Master Antioxidant for Recovery, Energy, and Healthspan Oct 09, 2025

Show notes

Glutathione isn't just another supplement, it's the master antioxidant your body depends on for performance, recovery, and longevity. In this episode, I break down the science behind glutathione and why I've made it part of my daily stack for nearly a decade.

We cover how glutathione neutralizes free radicals, supports detoxification, strengthens your immune system, and protects mitochondria, the power plants of your cells. You'll hear what the latest research shows about oral glutathione (yes, it works), why consistency is key, and how it directly impacts your recovery, energy, and even skin health.

I also share exactly how I use it, when I double up while traveling, how I stack it with pre-workouts for better pumps, and why I recommend fermented, clinically studied forms like CellShield.

If you want to train harder, recover faster, and slow down biological aging, this is a must-listen.

What's Discussed:

(00:04) The Importance of Glutathione Supplementation

(06:41) Beneficial Effects of Glutathione Supplementation

(11:08) Glutathione and Training Recovery

(16:53) Glutathione, Sleep, and Stress

(20:34) Optimizing Health and Performance

Thank you to our sponsors:

NAD + Cell Shield from Biostack Labs https://biostacklabs.com/kris
BiOptimizers - code KRIS10 for 10% off https://bioptimizers.com/

Find more from Kris:

Website: https://www.krisgethin.com/

Instagram: @krisgethin

Youtube: https://www.youtube.com/krisgethin Unmatched Supplements: https://www.unmatchedsupps.com/

227. GLP Q&A: Can You Lose Fat and Keep Muscle on GLP agonists? Oct 02, 2025

Show notes

Most people using GLP agonists are doing it wrong. Semaglutide? Tirzepatide? They're not magic pills, they're misunderstood tools. In this episode, I answer your most common questions and break down what these drugs actually do inside the body.

We get into the real science: how GLPs suppress appetite, slow digestion, improve insulin sensitivity, and change energy balance. I explain the difference between GLP‑1, dual agonists like tirzepatide (GLP + GIP), and next-gen options like retatrutide (GLP + GIP + glucagon).

You'll learn why fat loss happens, why muscle loss is a major risk, and how to train, eat, and supplement so you stay jacked, not soft. We cover the rebound effect when you stop, what stacks are worth considering, and how to avoid wrecking your gut or your gains in the process.

If you're serious about fat loss, muscle retention, and metabolic health, this is mandatory listening. These compounds can change your trajectory. Or wreck it. The difference is your discipline.

What's Discussed:

(00:01) Are GLP Drugs Just Fancy Appetite Suppressants? (02:57) The Real Reason You're Losing Muscle on Semaglutide (05:23) What Happens When You Come Off? The Rebound Most Miss (06:59) Using GLPs as an Athlete? Here's What Can Go Sideways (13:06) How to Actually Maximize GLPs Without Wrecking Your Gains

Thank you to our sponsors:

NAD + Cell Shield from Biostack Labs https://biostacklabs.com/kris
BiOptimizers - code KRIS10 for 10% off https://bioptimizers.com/

Find more from Kris:

Website: https://www.krisgethin.com/

Instagram: @krisgethin

Youtube: https://www.youtube.com/krisgethin

Unmatched Supplements: https://www.unmatchedsupps.com/

226. Why NAD3 Crushes NMN & NR (The Truth About Cellular Energy) Sep 25, 2025

Show notes

Most NAD+ supplements are fluff. NMN? NR? They're precursors, half the story. In this episode, I break down why NAD3 isn't just another molecule, it's the master key for energy, recovery, and longevity.

We get into the real science: how NAD+ fuels your mitochondria, repairs DNA, activates sirtuins, and slows aging at the cellular level. I explain why levels crash after 40, how stress, toxins, and training hammer your reserves, and why NMN/NR often fail thanks to CD38 and PARP overactivity.

You'll learn why NAD3 bypasses the weak links, how it stacks with spermidine, glutathione, and autophagy activators, and why Regen NAD is the one I actually use daily, because it works.

Forget the hype. This is metabolic firepower that hits. If you're overtrained, under-recovered, or want to stay biologically younger for longer: listen in.

What's Discussed:

[00:30] – What Is NAD+ and Why It's Non-Negotiable [03:30] – Why Your NAD Levels Plummet After 40 [07:15] – NMN & NR: Overhyped Precursors That Don't Deliver [09:30] – NAD3: The Smarter, More Effective Upgrade [11:00] – My Daily NAD Protocol (and Why IVs Suck)

Thank You for Our Sponsors:

NAD + Cell Shield from Biostack Labs https://biostacklabs.com/kris
BiOptimizers - code KRIS10 for 10% off https://bioptimizers.com/
Peptide Flask - Get your here and use KRIS10 is the code for 10% off.

My Go-To for Gut Health: Glutamine and Imuno-IGG from Unmatched Supplements: https://www.unmatchedsupps.com/collections/digestion-gut-health

Find more from Kris:

Website: https://www.krisgethin.com/ Website:https://www.unmatchedsupps.com

Instagram: @krisgethin

Youtube: https://www.youtube.com/krisgethin 2 Shred: https://www.unmatchedsupps.com/products/2shred

225. Mike Ryan's: Longevity at 59 and the Blueprint for Strength That Lasts Sep 18, 2025

Show notes

Most guys fall apart with age. Excuses pile up. Strength fades. But Mike Ryan proves you can get stronger every decade. At nearly 60, he's outlifting men half his age, and he's been doing it while training Hollywood's biggest names like Dwayne "The Rock" Johnson .

In this episode, we break down what actually drives longevity in fitness. Mindset over motivation. Why recovery, hydration, and sleep matter more than the latest trend. And why your environment will dictate your results more than any program.

Mike gets real about TRT and peptides, the role of cheat days, and what decades at Gold's Gym Venice have taught him about strength, discipline, and staying relevant. We also tackle overrated vs. underrated exercises, celebrity training under pressure, and how to avoid the social media nonsense that's making lifters weaker.

Mike Ryan is a Gold's Gym Venice legend who's trained top celebrities and athletes, including Dwayne "The Rock" Johnson. At nearly 60, he's still pushing massive weight and proving that longevity comes from discipline, mindset, and consistency.

What's Discussed:

(00:00) From Gold's Gym to Celebrity Training and Longevity
(10:31) Evolution of the Fitness Industry and Staying Relevant
(16:56) Training Secrets Recovery Habits and Performance Enhancers
(27:05) Pop Culture Conversations and Personal Insights
(33:47) The Shocking Cyberbullying Documentary That Left Us Speechless

Thank you to our sponsors:

NAD + Cell Shield from Biostack Labs https://biostacklabs.com/kris
BiOptimizers - code KRIS10 for 10% off https://bioptimizers.com/

Find more from Kris:

Website: https://www.krisgethin.com/

Instagram: @krisgethin

Youtube: https://www.youtube.com/krisgethin

2 Shred: https://www.unmatchedsupps.com/products/2shred

Find more from Mike Ryan:

Instagram: @mike_ryan_celebritytrainer

224. Why Oral Peptides Work (Even If "Experts" Say They Don't) Sep 11, 2025

Show notes

"Destroyed by the gut." "Zero absorption." "Only injectables work." This is BS.

In this episode, I break down why oral peptides aren't just working, they're evolving. I cover the science, the delivery tech, and the results I've lived through: cartilage regrowth, hormonal optimization, cognitive firepower.

You'll learn how short-chain peptides bypass gut breakdown via PEPT1. Why nano-carriers, mucoadhesive polymers, and smart pH triggers are rewriting absorption. And why anyone still parroting the "oral doesn't work" myth is stuck in 2005.

I show you my travel peptide stack, how I keep everything cold, and why oral bioregulators like Sigma, Testolutin, and Biomind are now staples in my rotation.

This isn't hype. This is recovery, immunity, and performance…elevated.

What's Discussed:

(00:06) Oral Peptides: Why the "Destroyed by the Gut" Claim is BS

(02:42) My Travel Stack: Fridge, Injectables, and Immune Armor

(04:39) Brain on Fire: The Peptides That Keep You Sharp

(08:19) Biohacking Absorption: How Oral Peptides Actually Work

(16:54) What Makes Next-Level Recovery

My Go-To for Gut Health: Glutamine and Imuno-IGG from Unmatched Supplements: https://www.unmatchedsupps.com/collections/digestion-gut-health

Find more from Kris:

Website: https://www.krisgethin.com/ Website:https://www.unmatchedsupps.com

Instagram: @krisgethin

Youtube: https://www.youtube.com/krisgethin 2 Shred: https://www.unmatchedsupps.com/products/2shred

223. Why Creatine Monohydrate Isn't Enough Anymore Sep 04, 2025

Show notes

You take creatine. You think it's working. But if you're bloated, cramping, or seeing zero gains, you're not absorbing it right.

Here's the truth: monohydrate saturates one transport pathway. Once that's full, you're done. Up to 30% of users feel nothing. Add GI issues and brain access problems, and you're building strength on a weak foundation.

In this episode, I break down CreGAAtine, a next-gen formula with creatine monohydrate, GAA, and B vitamins. It hits four pathways, not one. That means better muscle saturation, stronger brain uptake, and zero bloating.

I cover absorption, ATP regeneration, neuroprotection, and why this crushes the "non-responder" excuse. You get more power, more cognitive resilience, and faster recovery, without these side effects.

I show you how I take it, why it works year-round, and how it fits into a performance-first lifestyle.

Listen in. Then upgrade your creatine. Your strength, brain, and gut will thank you.

What's Discussed:

(00:01) Evolution of Creatine (01:22) Limitations of Monohydrate (04:13) Brain Absorption & Non-Responders (05:26) What Makes CreGAAtine Different (11:42) Benefits of Creatine Supplementation

Thank you to our sponsors:

NAD + Cell Shield from Biostack Labs https://biostacklabs.com/kris
BiOptimizers - code KRIS10 for 10% off https://bioptimizers.com/

My Go-To Creatine: CreGAAtine from Unmatched Supplements: https://www.unmatchedsupps.com/cregaatine-capsules

Find more from Kris:

Website: https://www.krisgethin.com/

Instagram: https://www.instagram.com/krisgethin/

Youtube: https://www.youtube.com/krisgethin

2 Shred: https://www.unmatchedsupps.com/products/2shred

222. UK vs US Grass-Fed Whey: What They're Not Telling You Aug 28, 2025

Show notes

My Go-To Protein: UK Pasture-Raised Whey Isolate from Unmatched Supplements

SHOP HERE: (BOGO 50% OFF SALE HAPPENING NOW): https://www.vitaminshoppe.com/p/isolate-grass-fed-whey-protein-rich-chocolate-2-lb-powder/unm-14114

You check the label. It says "grass-fed." You think you're getting the cleanest, most nutrient-rich protein possible.

But here's the truth: in the U.S., that label can mean almost nothing. Loopholes, grain finishing, inconsistent nutrient profiles, even hidden contaminants. And if you're using that protein daily? You're building your results on a shaky foundation.

In this episode, I break down the real difference between UK/Irish pasture-raised whey isolate and most U.S. "grass-fed" protein. You'll learn why sourcing, animal welfare, and processing methods matter for muscle growth, fat loss, recovery, and long-term health.

We'll talk nutrient density, bioactive fractions, contamination risks, sweetener choices, and how to spot marketing tricks designed to make cheap protein look premium. I'll show you exactly what I use, why I use it, and how to make sure your protein works with your health, not against it.

No fillers. No hype. Just facts you can use to choose better, recover faster, and perform longer.

Listen in. Then upgrade your protein.

What's Discussed:

00:01 – Why "grass-fed" on the label might not mean what you think

03:01 – The hidden factor that makes UK whey stand out

10:44 – The sweetener choice that could sabotage your results

My Go-To Protein: UK Pasture-Raised Whey Isolate from Unmatched Supplements

SHOP HERE: (BOGO 50% OFF SALE HAPPENING NOW): https://www.vitaminshoppe.com/p/isolate-grass-fed-whey-protein-rich-chocolate-2-lb-powder/unm-14114

Thank you to our sponsors:

NAD + Cell Shield from Biostack Labs https://biostacklabs.com/kris
BiOptimizers - code KRIS10 for 10% off https://bioptimizers.com/

Find more from Kris:

Website: https://www.krisgethin.com/

Instagram: https://www.instagram.com/krisgethin/

Youtube: https://www.youtube.com/krisgethin

2 Shred: https://www.unmatchedsupps.com/products/2shred

221. Burn Fat Without Losing Muscle + The 6 Strategies That Actually Work Aug 21, 2025

Show notes

You've been told you can't have both. That you need to choose between getting lean or staying muscular.

That's BS and in this episode, I break down the exact strategies I use with high-performance clients around the world to help them burn fat without sacrificing size, strength, or muscle mass.

You'll learn how to leverage high-protein intake, amino acid timing, heat and cold therapy, cutting-edge peptides, fat-loss supplements, and deep sleep optimization, all backed by science and proven in practice.

This is about performing at your peak, recovering faster, and protecting your hard-earned muscle while cutting down.

No fluff. No shortcuts. Just precision protocols that get real results.

Listen in, and upgrade your cut.

What's Discussed:

00:26 – Burn Fat Without Shrinking: The Real Strategy 02:33 – Why High Protein Protects Muscle in a Cut 04:41 – How to Stay Anabolic During Fasted Cardio 06:08 – Use Sauna + Ice to Trigger Fat Loss and Recovery 13:36 – Poor Sleep Is Killing Your Gains—Here's Why

Thank you to our sponsors:

NAD + Cell Shield from Biostack Labs https://biostacklabs.com/kris
BiOptimizers - code KRIS10 for 10% off https://bioptimizers.com/

Find more from Kris:

Website: https://www.krisgethin.com/

Instagram: https://www.instagram.com/krisgethin/

Youtube: https://www.youtube.com/krisgethin 2 Shred: https://www.unmatchedsupps.com/products/2shred

220. Unlock Elite Results and Reverse Your Age with Blood Work & Wearables Aug 14, 2025

Show notes

You've followed every program. Taken every "science-backed" supplement. Tracked your sleep, steps, macros, and macros again. But results? Still inconsistent. Still frustrating. Still not reflecting the effort.

That's because you're using generic tools for a highly specific machine, your body.

In this episode, I walk you through the real game-changer: data-driven personalization. DNA testing. You'll learn how to stop wasting time on plans that weren't made for you, and start building a system based on your unique biology.

I'll share the tools I use with VIP+ clients and myself to optimize recovery, cut fat, gain muscle, and extend healthspan well past 50. This isn't optional anymore. If you want elite results, you need elite intel.

No fluff. No hype. Just hard data and harder action.

Listen in. Then upgrade everything.

What's Discussed:

01:20 – Why cookie-cutter diets and generic plans are dead 03:55 – The real power of DNA: what your genes say about your gains 06:50 – How CGMs expose "healthy" foods that sabotage your energy 10:30 – Using HRV, blood work, and wearables to decide when to push or pull back 12:40 – Client case studies: stress, stubborn fat, and reversing biological age

Thank you to our sponsors:

NAD + Cell Shield from Biostack Labs https://biostacklabs.com/kris
BiOptimizers - code KRIS10 for 10% off https://bioptimizers.com/

Find more from Kris:

Website: https://www.krisgethin.com/

Instagram: https://www.instagram.com/krisgethin/

Youtube: https://www.youtube.com/krisgethin

2 Shred: https://www.unmatchedsupps.com/products/2shred

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