The Cannabis Consult w/ Dr. Jamie Corroon, ND, MPH

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Michelle Sexton, ND (Part 1) - Cannabis & Immunity Apr 06, 2020

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Dr. Sexton is the Endocannabinoid System Doctor (ecsdoctor.com). She is Assistant Adjunct Professor at UCSD in the Department of Anesthesiology. She graduated from Bastyr University in 2008. She completed a postdoctoral fellowship at the University of Washington where she formally studied the endocannabinoid system for 6 years. Her NIH-funded pre-doctoral and postdoctoral research on the topic of cannabinoids and their roles in neuroinflammation and neurodegeneration investigated cannabis use and impact on inflammatory markers. She has continued her research into health effects of cannabis at UCSD. Prior to medical school, she was a midwife and herbalist for 15 years. Dr. Sexton has presented he research internationally and published in peer-reviewed journals. Dr. Sexton’s clinical practice, research and teaching focus on the endocannabinoid system and roles for integrative medicine, including cannabis to treat a range of conditions across the lifespan. She is a member of the International Cannabinoid Research Society, the International Association of Cannabinoid Medicine The Society of Cannabis Clinicians and the American Association of Naturopathic Doctors. She is a Board Member on the California Association of Naturopathic Doctors. She maintains a medical practice in the Pacific Beach neighborhood of San Diego, CA.When not caring for patients or pursuing research activities, you can find her in the garden, paying music, playing with grandchildren, swimming or riding her bike to the beach for a surf session! Part 1 1:40 - Michelle’s background 5:00 - Immunity, inflammation and the CB2 receptor 6:22 - The endocannabinoid & immune systems 7:00 - CB2 receptors on white blood cells 10:00 - Cross-talk between systems, TNF-alpha 10:40 - What is immune suppression? Is it good? 12:30 - CBD and inflammation. Measuring the CB2 receptor 14:35 - CBD and other receptors 14:50 - TRPV1 receptor 15:50 - Cannabis modulating the immune system 18:20 - Cannabinoids and COVID-19 20:00 - Dosing of THC 21:05 - The role of TNF-alpha 23:35 - Sepsis 25:00 - Smoking & risks of complications 27:12 - Cannabinoids won’t protect you from COVID-19 Michelle Sexton’s clinical practice: http://www.msextonnd.com Online course: Women's Health and Cannabis Across the LIfespan and Endocannabinoid System 101 https://ecsdoctor.teachable.com

Michelle Sexton, ND (Part 2) - Cannabis & Women's Health Apr 06, 2020

Show notes

Dr. Sexton is offering $50 off (33% discount)for her online course: Women's Health and Cannabis Across the LIfespan and Endocannabinoid System 101 Code: WOMEN Dr. Sexton is the Endocannabinoid System Doctor (ecsdoctor.com). She is Assistant Adjunct Professor at UCSD in the Department of Anesthesiology. She graduated from Bastyr University in 2008. She completed a postdoctoral fellowship at the University of Washington where she formally studied the endocannabinoid system for 6 years. Her NIH-funded pre-doctoral and postdoctoral research on the topic of cannabinoids and their roles in neuroinflammation and neurodegeneration investigated cannabis use and impact on inflammatory markers. She has continued her research into health effects of cannabis at UCSD. Prior to medical school, she was a midwife and herbalist for 15 years. Dr. Sexton has presented he research internationally and published in peer-reviewed journals. Dr. Sexton’s clinical practice, research and teaching focus on the endocannabinoid system and roles for integrative medicine, including cannabis to treat a range of conditions across the lifespan. She is a member of the International Cannabinoid Research Society, the International Association of Cannabinoid Medicine The Society of Cannabis Clinicians and the American Association of Naturopathic Doctors. She is a Board Member on the California Association of Naturopathic Doctors. She maintains a medical practice in the Pacific Beach neighborhood of San Diego, CA.When not caring for patients or pursuing research activities, you can find her in the garden, paying music, playing with grandchildren, swimming or riding her bike to the beach for a surf session! Part 2 1:55 - Cannabis & pregnancy 3:30 - Menstrual cramps 5:00 - CBD & smooth muscle spasms 7:00 - CBD dosing 9:00 - What is bioavailability? 9:35 - Suppositories 12:30 - Michelle’s online course on the ECS and women’s health 18:00 - The Endocannabinoid System 18:50 - Beta-caryophyllene as a dietary cannabinoid 21:09 - Clinical Endocannabinoid Deficiency 23:20 - Hyperemesis gravidarum (Nausea and vomiting during pregnancy) 26:50 - Overall thoughts on cannabis & women’s health Michelle Sexton’s clinical practice: http://www.msextonnd.com Online course: Women's Health and Cannabis Across the LIfespan and Endocannabinoid System 101 https://ecsdoctor.teachable.com Papers mentioned: Plasma levels of the endocannabinoid anandamide in women--a potential role in pregnancy maintenance and labor? https://www.ncbi.nlm.nih.gov/pubmed/15531501

Cannabinoids in Clinical Practice - Mike Hennesy Oct 04, 2019

Show notes

In his role as Director of Innovation, Mike Hennesy continues to position Wana Brands on the leading-edge of cannabis science and technologies as the market leader in infused product innovation. Hennesy oversees a diverse range of responsibilities including research and development, business analytics, training programs, and strategic partnership building. Hennesy developed Wana’s online interactive training program for budtenders and employees that covers the science of the endocannabinoid system. He also directed the development of Wana’s disposable vape line, including the line’s unique proprietary blend. Prior to his role as Director of Innovation managed a sales team of seven and has been instrumental in Wana’s availability in the vast majority of Colorado’s dispensaries and three-year growth rate of 269%. A native of Northern Virginia, Hennesy graduated from The University of Maryland with a Bachelor of Science in Environmental Science and Technology (ENST) in 2012. He is currently enrolled in a Master Program for Cannabis Science and Therapeutics at The University of Maryland’s School of Pharmacy. Hennesy served as Vice President of the ENST Society and was an active member of the Washington, D.C. chapters of NORML and Students for Sensible Drug Policy (SSDP). Hennesy brings a diverse background to the industry as a certified Rescue Diver, Eagle Scout and outdoorsman. When not working, he still finds time for camping, hiking and snowboarding in the mountains around Boulder, Colo. 01:58 - The University of Maryland Masters of Science Program in Medical Cannabis Science and therapeutics 02:54 – Background on Wanna Brands, a Colorado-based manufacturer of edible cannabis products 04:18 – Dr. Corroon’s background in Naturopathic Medicine and public health. How he entered the field of medical cannabis. 13:54 - How cannabis plays a role in treatment plans and patient recommendations 17:45 - CBD and THC ratios 20:16 – Dr. Corroon’s research 23:33 - Clinical research and pharmacology utilizing isolated cannabinoids versus extracts 25:14 - Research into hemp-derived CBD products 26:46 – Limitations in using CBD and THC in clinical practice 29:18 – Future directions in cannabis research 31:35 – The need for education in medical cannabis 34:24 - Future plans for the Center for Medical Cannabis Education 35:25 – Soon-to-be-published research by Dr. Corroon 37:51 – Hemp-derived CBD products are everywhere 38:56 – Health-related claims on labels of cannabis products

CBD, Hemp & Pet Health - Greg Tilford Mar 18, 2019

Show notes

Greg Tilford is a leading force and early pioneer in the field of veterinary botanical medicine. His 24 years of professional experience as a formulating herbalist and educator began while living off the grid for 11 years in the rugged mountains of Montana. There he engaged in an intensive study of medicinal plants, their human and animal uses, and the intricate, interconnected relationships that exist between all living things that depend upon them. His work transcends conventional science to explore the roles of plants and animals as teachers and keepers of planetary wellness. Greg has authored four books, including the acclaimed “Herbs for Pets, The Natural Way to Enhance Your Pets Life” and dozens of published articles. In recent years he has been traveling the world, teaching and lecturing to audiences ranging from lay pet owners to veterinarians and institutions of higher education as far away as Japan, Taiwan, Thailand and Central America. Part of his outreach effort is bringing bioregional herbalism into awareness, so common plants can be accessed and safely used in the care of animals anywhere, even in the most impoverished regions. Greg’s most current work focuses on the human-animal bond, and how plants, animals and earth are interlinked. Greg is the co-founder and president of Animal Essentials, a company that has been manufacturing natural pet supplements since 1995. 1:15 - Greg's background 3:40 - Plants & animals 5:10 - Evidence for plant medicine 7:23 - Isolates v. extracts 11:00 - Safety of herbal extracts 12:30 - National Animal Supplement Council adverse events reporting system 16:10 - Learning to write 19:45 - Working w/ Vets, Animal Essentials 21:10 - Animal Essentials hemp products 26:00 - European hemp pedigrees 27:20 - CBD in pets 33:10 - Dosing CBD in pets 42:23 - Vet education on the endocannabinoid system 45:10 - Vets using THC in animals 46:00 - Adverse effects of CBD in animals 46:50 - Conditions being treated in animals 48:12 - Sourcing CBD, quality control 49:20 - Hemp v. marijuana 53:25 - Using leaf v. flower 54:25 - Future directions for Animal Essentials 55:39 - Azadirachtin in neem oil (Pesticide) 56:36 - Organic certification of hemp

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