Stay ConnectedNew discoveries, everyday mysteries, and the science behind the headlines — in just under 15 minutes. It’s science for everyone, using a lot of creativity and a little humor. Join hosts Emily Kwong and Regina Barber for science on a different wavelength.
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The climate meeting known as COP27 has wrapped. Representatives from almost 200 countries attended to talk about how to tackle climate change and how to pay for the costs of its effects that the world is already seeing. Rebecca Hersher and Michael Copley from NPR's Climate Desk talk with Emily about why the meeting went into overtime, three big things that came out of it, and the long and bumpy road still ahead to reduce greenhouse gas emissions.
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The idea came to Uma Valeti while he was working on regrowing human tissue to help heart attack patients: If we can grow tissue from cells in a lab, why not use animal cells to grow meat?
Food production accounts for as much as a third of the world's greenhouse gas emissions. The idea behind cultivated meat is to help feed the world while dramatically reducing human contributions to global warming and avoiding killing animals. NPR Health Correspondent Allison Aubrey has been visiting production facilities and talking with both food and climate scientists to understand how far away lab-grown meat is from store shelves, and what a meal of cultivated chicken tastes like.
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In the mornings, Sonia Vallabh and Eric Minikel's first job is to get their two garrulous kids awake, fed and out the door to daycare and kindergarten. They then reconvene at the office and turn their focus to their all-consuming mission: to cure, treat, or prevent genetic prion disease.
Prions are self-replicating proteins that can cause fatal brain disease. For a decade, Sonia Vallabh has been living with the knowledge that she has a genetic mutation that will likely cause in her the same disease that claimed her mother's life in 2010. Upon discovering she had the mutation, Sonia and her husband made a massive pivot: They went from careers in law and urban planning to earning their Ph.D.s, and founding a prion research lab at the Broad Institute of MIT and Harvard. On today's episode, Sonia and Eric talk with Short Wave's Gabriel Spitzer about what it's like to run a lab with one's spouse, cope with the ticking clock in Sonia's genes, and find hope in a bleak diagnosis.
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The first time Sonia Vallabh understood something was very wrong with her mother Kamni was on the phone on her mom's 52nd birthday. She wasn't herself. By the end of that year, after about six months on life support, Kamni had died.
The disease she died from would upend Sonia and her husband Eric's lives, and send them on a careening journey toward a completely new calling: to prevent or cure the disease that's stalking Sonia's family." Sonia Vallabh and Eric Minikel join Short Wave to tell their story in this second of three episodes on prion disease.
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Prions are biological anomalies – self-replicating, not-alive little particles that can misfold into an unstoppable juggernaut of fatal disease. Prions don't contain genes, and yet they make more of themselves. That has forced scientists to rethink the "central dogma" of molecular biology: that biological information is always passed on through genes. The journey to discovering, describing, and ultimately understanding how prions work began with a medical mystery in a remote part of New Guinea in the 1950s. The indigenous Fore people were experiencing a horrific epidemic of rapid brain-wasting disease. The illness was claiming otherwise healthy people, often taking their lives within months of diagnosis. Solving the puzzle would help unlock one of the more remarkable discoveries in late-20th-century medicine, and introduce the world to a rare but potent new kind of pathogen. For the first episode in a series of three about prion disease, Short Wave's Gabriel Spitzer shares the science behind these proteins with Emily Kwong, and explains why prions keep him awake at night.
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Climate negotiations continue at COP27 in Sharm el-Sheikh, Egypt. Tens of thousands of attendees from around the world have gathered in the seaside resort town. They've come to discuss some of the key issues to figure out how to combat climate change, remedy its effects, and to focus on implementing the big changes discussed last year in Glasgow.
Correspondent Nathan Rott joins Emily Kwong to walk through the biggest debates at this year's COP, like loss and damage payments. And, he talks about how the war in Ukraine and the U.S. midterm elections are affecting discussions as well.
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Today, we pass the mic to our colleagues at All Things Considered to share the first piece in their series on the impact of climate change, global migration and far-right politics. They begin with the story of Mamadou Thiam, a Senegalese man living in a temporary shelter created by the United Nations. He is from a family of fishermen, but floods have destroyed his home. In the past when there was flooding, people could relocate for a few months and then return. But more flooding means leaving may become permanent.
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A pivotal week in Corey Gray's life began with a powwow in Alberta and culminated with a piece of history: the first-ever detection of gravitational waves from the collision of two neutron stars. Corey was on the graveyard shift at LIGO, the Laser Interferometer Gravitational Observatory in Hanford, Washington, when the historic signal came. Corey tells Short Wave Scientist in Residence Regina G. Barber about the discovery, the "Gravitational Wave Grass Dance Special" that preceded it, and how he got his Blackfoot name.
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If Earth heats up beyond 1.5 degrees, the impacts don't get just slightly worse--scientists warn that abrupt changes could be set off, with devastating impacts around the world. As the 27th annual climate negotiations are underway in Egypt and the world is set to blow past that 1.5°C warming threshold,
Emily Kwong talks to climate correspondents Rebecca Hersher and Lauren Sommer about three climate tipping points--points of no return that could cause big changes to the Earth's ecosystems.
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Researchers are launching a make-or-break study to test the conventional wisdom about what causes Alzheimer's disease. And in a recent small study, the antidepressant effects of ketamine lasted longer when an intravenous dose was followed with computer games featuring smiling faces or words aimed at boosting self-esteem. As science correspondent Jon Hamilton heads to the Society for Neuroscience's annual meeting, he talks to Aaron Scott about his most recent reporting on depression and Alzheimer's, and previews what he'll be talking to researchers about at the meeting.
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