Stay ConnectedDr Karl’s a curious optimist. Join him as he explores the latest developments in science with leading researchers and communicators.
And remember, it’s never too late for a happy childhood.
Series Producer: Isabelle Benton
Technical Producer: Maya Cook
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***Prof Lucas would like to provide the following clarification in regards to comments relating to prenatal BPA exposure and male autism spectrum disorder: "A positive association between high prenatal BPA exposure and ASD diagnosis was only seen in male offspring with a genetic predisposition to low aromatase enzyme activity." Professor Michaela Lucas, an Immunologist and Immunopathologist researching the health impacts of plastics, joins me to explore what microplastics and plastic-associated chemicals may be doing inside our bodies. We discuss how compounds like bisphenols and phthalates can act like hormone-mimicking molecules, the evidence linking plastic exposure to developmental and fertility concerns, and why some estimates of microplastics in the body may have been overstated. Professor Lucas also shares insights from her ongoing study in Perth examining how everyday exposures, particularly ultra-processed foods packaged in plastic, may contribute to microplastics in the body. Listeners can subscribe to receive the study results when they're released via www.uwa.edu.au/projects/the-perth-trial.
Linkedin: @prof-michaela-lucas/
I'm joined by Dr. Anna Broinowski - Senior Lecturer and Director of the Master of Film and Screen Arts at Sydney College of the Arts, University of Sydney - to unpack the rise of deepfakes and synthetic media.
We discuss the emergence of deepfake pornography in 2017, the fact that around 90% of deepfake content targets women and girls, and the growing use of AI in propaganda. From political manipulation to fake ads impersonating me (!), this episode explores how deepfakes are eroding trust, and what that means for the future of media, filmmaking and truth more broadly.
Nitrous oxide (better known as "laughing gas") is widely used in medicine as a safe anaesthetic and pain reliever. It's also found in whipped cream canisters and even used in car engines. But Angela Chiew, toxicologist and Associate Professor at UNSW, joins me to set the record straight: the growing recreational misuse of this easily accessible gas is causing serious long-term harm, including nerve damage, cognitive damage, weakening of the spinal cord and mobility impairments. Cases of misuse are rising globally, likely driven by how easy it is to legally purchase the drug in many countries. This episode unpacks the hidden dangers behind a gas many once thought was just a harmless high. Linkedin: Angela Chiew X: AngelaChiewA
In the final episode of the Great AI Safety Debrief series with Dr. Petr Lebedev, we discuss job eradication, AI alignment and the rise in cases of AI deceiving humans. Petr unpacks ideas like AI scheming, situation awareness, parasitic relationships between humans and machines, and even the possibility of AI developing belief systems of its own. We end by zooming out to existential risk, Alan Turing's early warnings, and why aligning AI with human values may be one of the most difficult (and urgent) challenges humanity must face.
Linkedin: Petr Lebedev palisaderesearch.org/
In part two, Dr. Petr Lebedev and I dive deeper into how modern AI systems are grown, not programmed, and the emergence of Shutdown Resistance. We explore AI performance in math and coding competitions, the rapid evolution of ChatGPT models, and why companies are already letting AI write the majority of their code. Petr explains how huge investments globally are pushing these systems forward faster than we can fully understand or control. The final episode in this 3 part series drops next week! Linkedin: Petr Lebedev palisaderesearch.org/
Intelligence is emerging from sand and less than 1% of the population seems to care! Physicist and science communicator Dr. Petr Lebedev joins the podcast following his SXSW talk to explore the rapid advancement of AI and how it's dramatically shifting the global status quo. From completing a PhD in physics and writing for Veritasium, to leading science communication at Palisade Research, Petr steps in to bring some clarity to the weird, wild, and worrying sides of AI. Did you know that no one truly understands how large language models actually work? We go deep on misaligned systems, humanoid and dog robots, and why many experts believe AI could pose a serious global risk. Is AI our greatest tool? Or something we're slowly losing control of? This conversation is big, so we've split it into three parts. Part two drops next week.
A mysterious glow from the centre of the Milky Way has scientists intrigued. Astrophysicist Geraint Lewis explains how this gamma-ray excess, first detected in 2009, could be evidence of dark matter particles interacting deep in our galaxy. With dark matter believed to make up a vast, invisible halo that holds galaxies together, uncovering the source of this glow may bring us closer to understanding what the universe is really made of.
www.geraintflewis.com/ Linkedin: geraint-lewis-4a499b1
In this episode, I'm joined by Professor Clare Collins, Australian dietitian and Professor of Nutrition and Dietetics at the University of Newcastle. Clare is my go-to expert when it comes to all things nutrition, and today she's here to unpack the often confusing world of processed and ultra-processed foods.
We dive into what really separates the two, explore the role of additives, emulsifiers, and flavour enhancers, and discuss how some of these ingredients, designed to make foods more appealing, may be doing our health more harm than good. Plus, she shares practical, no-nonsense tips to help you make smarter choices next time you're wandering the grocery aisles.
Check out Clare's free online resource, No Money No Time, for simple, budget-friendly recipes and nutrition advice - nomoneynotime.com.au/ Follow Clare on X: @ProfCCollins and LinkedIn: Clare Collins.
In part two with Online Safety Consultant Troy Hunt (Have I Been Pwned), we unpack the risks of online age verification in light of Australia's social media ban, including the personal data (often times photos or government documents) sites may demand, and how these security practices can be questionable. Troy explains why we should be thinking more about data minimisation and the dangers of unnecessary data retention. We go through the safest multi-factor authentication methods, from SMS to physical keys, and Troy shares a personal phishing story, reminding us that no-one is immune to hacking thanks to increasingly sophisticated phishing techniques. https://haveibeenpwned.com/ Linkedin: Troy Hunt
In part two, Associate Professor Marian-Andrei Rizoiu from the University of Technology Sydney explains how misinformation and toxic online cultures spread. We dive into the "manosphere pipeline" targeting boys as young as 10, its real-world impacts on schools and families, and how it can escalate into radicalisation. Rizoiu outlines his team's six-stage pipeline - from passive curiosity to active involvement - and why simply giving people facts doesn't solve the problem. Instead, this is a human challenge, and his lab is exploring new ways to diffuse and counter online misinformation before it turns dangerous. Linkedin: Marian-Andrei Rizoiu
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