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    Sean Carroll’s Mindscape: Science, Society, Philosophy, Culture, Arts, and Ideas

    Ever wanted to know how music affects your brain, what quantum mechanics really is, or how black holes work? Do you wonder why you get emotional each time you see a certain movie, or how on earth video games are designed? Then you’ve come to the right place. Each week, Sean Carroll will host conversations with some of the most interesting thinkers in the world. From neuroscientists and engineers to authors and television producers, Sean and his guests talk about the biggest ideas in science, philosophy, culture and much more.

    Advertise

    Copyright: © Sean Carroll 2026

    • Apple Podcasts
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    Latest Episodes:
    255 | Michael Muthukrishna on Developing a Theory of Everyone Oct 30, 2023
    Show notes

    A "Theory of Everything" is physicists' somewhat tongue-in-cheek phrase for a hypothetical model of all the fundamental physical interactions. Of course, even if we had such a theory, it would tell us nothing new about higher-level emergent phenomena, all the way up to human behavior and society. Can we even imagine a "Theory of Everyone," providing basic organizing principles for society? Michael Muthukrishna believes we can, and indeed that we can see the outlines of such a theory emerging, based on the relationships of people to each other and to the physical resources available.

    Blog post with transcript: https://www.preposterousuniverse.com/podcast/2023/10/30/255-michael-muthukrishna-on-developing-a-theory-of-everyone/

    Support Mindscape on Patreon.

    Michael Muthukrishna received his Ph.D. in psychology from the University of British Columbia. He is currently Associate Professor of Economic Psychology at the London School of Economics and Political Science. Among his awards are an Emerging Scholar Award from the Society for Personality and Social Psychology and a Dissertation Excellence Award from the Canadian Psychological Association. His new book is A Theory of Everyone: The New Science of Who We Are, How We Got Here, and Where We're Going.

    • Web site
    • LSE web page
    • Google Scholar publications
    • Wikipedia

    254 | William Egginton on Kant, Heisenberg, and Borges Oct 23, 2023
    Show notes

    It can be tempting, when first introduced to a deep concept of physics like Heisenberg's uncertainty principle, to draw grand philosophical conclusions about the impossibility of knowing anything precisely. That is generally a temptation to be resisted, just because it's so easy to do it wrong. But there is absolutely a place for a careful humanistic synthesis of these kinds of scientific ideas with other ideas, for example from philosophy or literature. That's the kind of task William Egginton takes on in his new book The Rigor of Angels, which compares the work of philosopher Immanuel Kant, physicist Werner Heisenberg, and author Jorge Luis Borges, three thinkers who grappled with limitations on our aspirations to know reality directly.

    Blog post with transcript: https://www.preposterousuniverse.com/podcast/2023/10/23/254-william-egginton-on-kant-heisenberg-and-borges/

    Support Mindscape on Patreon.

    William Egginton received his Ph.D. in Comparative Literature from Stanford University. He is currently the Decker Professor in the Humanities and Director of the Alexander Grass Humanities Institute at Johns Hopkins. He is the author of numerous books on literature, literary theory, and philosophy. In addition to The Rigor of Angels, he has an upcoming book on the work of Chilean film director Alejandro Jodorowsky.

    • Web site
    • Johns Hopkins web page
    • Wikipedia
    • Amazon author page

    253 | David Deutsch on Science, Complexity, and Explanation Oct 16, 2023
    Show notes

    David Deutsch is one of the most creative scientific thinkers working today, who has as a goal to understand and explain the natural world as best we can. He was a pioneer in quantum computing, and has long been an advocate of the Everett interpretation of quantum theory. He is also the inventor of constructor theory, a new way of conceptualizing physics and science more broadly. But he also has a strong interest in philosophy and epistemology, championing a Popperian explanation-based approach over a rival Bayesian epistemology. We talk about all of these things and more, including his recent work on the Popper-Miller theorem, which specifies limitations on inductive approaches to knowledge and probability.

    Blog post with transcript: https://www.preposterousuniverse.com/podcast/2023/10/16/253-david-deutsch-on-science-complexity-and-explanation/

    Support Mindscape on Patreon.

    David Deutsch received his Ph.D. in theoretical physics from the University of Oxford. He is currently a visiting professor in the Department of Atomic and Laser Physics at Oxford. He is a pioneer in quantum computation as well as initiating constructor theory. His books include The Fabric of Reality and The Beginning of Infinity. Among his awards including the Dirac Prize, the Dirac Medal, the Edge of Computation Science Prize, the Isaac Newton Medal, the Breakthrough Physics Prize, and a Royal Society Fellowship.

    • Web site
    • Oxford web page
    • Google Scholar publications
    • Amazon author page
    • Wikipedia
    • TED talk: After Billions of Years of Monotony, the Universe is Waking Up

    AMA | October 2023 Oct 09, 2023
    Show notes

    Welcome to the October 2023 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Patreons, whittle them down to a more manageable number -- based primarily on whether I have anything interesting to say about them, not whether the questions themselves are good -- and sometimes group them together if they are about a similar topic. Enjoy!

    Blog post with questions and transcript: https://www.preposterousuniverse.com/podcast/2023/10/09/ama-october-2023/

    Support Mindscape on Patreon.


    252 | Hannah Ritchie on Keeping Hope for the Planet Alive Oct 02, 2023
    Show notes

    Our planet and its environment are in bad shape, in all sorts of ways. Those of us who want to improve the situation face a dilemma. On the one hand, we have to be forceful and clear-headed about how the bad the situation actually is. On the other, we don't want to give the impression that things are so bad that it's hopeless. That could -- and, empirically, does -- give people the impression that there's no point in working to make things better. Hannah Ritchie is an environmental researcher at Our World in Data who wants to thread this needle: things are bad, but there are ways we can work to make them better.

    Blog post with transcript: https://www.preposterousuniverse.com/podcast/2023/10/02/252-hannah-ritchie-on-keeping-hope-for-the-planet-alive/

    Support Mindscape on Patreon.

    Hannah Ritchie received her Ph.D. in geosciences from the University of Edinburgh. She is currently Senior Researcher and the Head of Research at Our World in Data, and a researcher at the Oxford Martin Programme in Global Development at the University of Oxford. Her upcoming book is Not the End of the World: How We Can Be the First Generation to Build a Sustainable Planet.

    • Web site
    • Oxford web page
    • Google scholar publications
    • Substack
    • Wikipedia

    251 | Rosemary Braun on Uncovering Patterns in Biological Complexity Sep 25, 2023
    Show notes

    Biological organisms are paradigmatic emergent systems. That atoms of which they are made mindlessly obey the local laws of physics; even cells and organs do their individual jobs without explicitly understanding the larger whole of which they are a part. And yet the system as a whole functions beautifully, with apparent purpose and function. How do the small parts come together to form the greater whole? I talk with biophysicist Rosemary Braun about what we're learning about collective behavior within organisms from the modern era of huge biological datasets, especially crucial aspects like timekeeping (with bonus implications for dealing with jet lag).

    Support Mindscape on Patreon.

    Blog post with transcript: https://www.preposterousuniverse.com/podcast/2023/09/25/251-rosemary-braun-on-uncovering-patterns-in-biological-complexity/

    Rosemary Braun received her Ph.D. in physics from the University of Illinois at Urbana-Champaign, and an M.P.H. in biostatistics from Johns Hopkins. She is currently an associate professor of molecular biosciences, applied math, and physics at Northwestern University and external faculty at the Santa Fe Institute.

    • Lab web page
    • Northwestern faculty page
    • Google Scholar publications

    250 | Brendan Nyhan on Navigating the Information Ecosystem Sep 18, 2023
    Show notes

    The modern world inundates us with both information and misinformation. What are the forces that conspire to make misinformation so prevalent? Can we combat the flow of misinformation, perhaps by legal restrictions? Would that even be a good idea? How can individuals help distinguish between true and false claims as they come in? What are the biases that we are all subject to? I talk to political scientist Brendan Nyhan about how information and misinformation spread, and what we can do as individuals and as a society to increase the amount of truth we all believe.

    Blog post with transcript: https://www.preposterousuniverse.com/podcast/2023/09/18/250-brendan-nyhan-on-navigating-the-information-ecosystem/

    Support Mindscape on Patreon.

    Brendan Nyhan received his Ph.D. in political science from Duke University. He is currently James O. Freedman professor of government at Dartmouth College. Among his awards are an Emerging Scholar award from the American Political Science Association, a Guggenheim Fellowship, and election to the American Academy of Arts and Sciences.

    • Web site
    • Dartmouth web page
    • Google Scholar publications
    • Wikipedia

    249 | Peter Godfrey-Smith on Sentience and Octopus Minds Sep 11, 2023
    Show notes

    The study of cognition and sentience would be greatly abetted by the discovery of intelligent alien beings, who presumably developed independently of life here on Earth. But we do have more than one data point to consider: certain vertebrates (including humans) are quite intelligent, but so are certain cephalopods (including octopuses), even though the last common ancestor of the two groups was a simple organism hundreds of millions of years ago that didn't have much of a nervous system at all. Peter Godfrey-Smith has put a great amount of effort into trying to figure out what we can learn about the nature of thinking by studying how it is done in these animals with very different brains and nervous systems.

    Blog post with transcript: https://www.preposterousuniverse.com/podcast/2023/09/11/249-peter-godfrey-smith-on-sentience-and-octopus-minds/

    Support Mindscape on Patreon.

    Peter Godfrey-Smith received his Ph.D. in philosophy from the University of California, San Diego. He is currently professor in the School of History and Philosophy of Science at the University of Sydney. Among his books are Other Minds: The Octopus, the Sea, and the Deep Origins of Consciousness and Metazoa: Animal Life and the Birth of the Mind.

    • Web site
    • University of Sydney web page
    • Google Scholar publications
    • PhilPeople profile
    • Wikipedia
    • Amazon author page

    Here are some of the papers mentioned in this episode:

    • Crook (2021), Octopus pain
    • Gibbons et al. (2022), Bee pain
    • Gutnick et al. (2011), Octopus arm behavior

    AMA | September 2023 Sep 04, 2023
    Show notes

    Welcome to the September 2023 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Patreons, whittle them down to a more manageable number -- based primarily on whether I have anything interesting to say about them, not whether the questions themselves are good -- and sometimes group them together if they are about a similar topic. Enjoy!

    Blog post with questions and transcript: https://www.preposterousuniverse.com/podcast/2023/09/04/ama-september-2023/

    And you can now pre-order The Biggest Ideas in the Universe Vol. 2: Quanta and Fields!


    248 | Yejin Choi on AI and Common Sense Aug 28, 2023
    Show notes

    Over the last year, AI large-language models (LLMs) like ChatGPT have demonstrated a remarkable ability to carry on human-like conversations in a variety of different concepts. But the way these LLMs "learn" is very different from how human beings learn, and the same can be said for how they "reason." It's reasonable to ask, do these AI programs really understand the world they are talking about? Do they possess a common-sense picture of reality, or can they just string together words in convincing ways without any underlying understanding? Computer scientist Yejin Choi is a leader in trying to understand the sense in which AIs are actually intelligent, and why in some ways they're still shockingly stupid.

    Blog post with transcript: https://www.preposterousuniverse.com/podcast/2023/08/28/248-yejin-choi-on-ai-and-common-sense/

    Support Mindscape on Patreon.

    Yejin Choi received a Ph.D. in computer science from Cornell University. She is currently the Wissner-Slivka Professor at the Paul G. Allen School of Computer Science & Engineering at the University of Washington and also a senior research director at AI2 overseeing the project Mosaic. Among her awards are a MacArthur fellowship and a fellow of the Association for Computational Linguistics.

    • University of Washington web page
    • Google Scholar publications
    • Wikipedia

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