Physician Assistant Exam Review

Latest Episodes:

S2 E082 Hyper-coagulability Aug 03, 2021

Show notes

Hypercoagulable states (Thrombophilia) Where is the problem? Clotting Factors Too many Too active Platelets Too many Too active Vascular injury Surgery Trauma Stasis Virchow’s triad Stasis Hypercoagulable state Vascular injury German doctor and scientist who first described the mechanism for a pulmonary embolism. The name Virchow’s triad was not used until well after his death. […]

The post S2 E082 Hyper-coagulability appeared first on Physician Assistant Exam Review.

S2 E081 Coagulation Disorders Jul 20, 2021

Show notes

Coagulation Factor Disorders von Willebrand Disease A spectrum of low production to production of poorly functioning von Willebrand’s Factor. von Willebrand’s factor (vWF) has two major functions. vWF helps platelets to stick together in the subendothelial collagen vWF binds to and maintains Factor VIII in circulation. Factor VIII breaks down very quickly in the bloodstream […]

The post S2 E081 Coagulation Disorders appeared first on Physician Assistant Exam Review.

S2 E080 Clotting overview Jul 08, 2021

Show notes

Our two main players in coagulation are platelets and clotting factors. To help make things clear we can split up these two agents into separate categories even though the work in concert. Primary hemostasis When a blood vessel is damaged, the subendothelium spaces are exposed to blood. This triggers a number of events designed to […]

The post S2 E080 Clotting overview appeared first on Physician Assistant Exam Review.

S2 E079 Lymphoma and an important tactic for the PANCE Jun 22, 2021

Show notes

Lymphoma A group of malignancies that develop from lymphocytes There are over 80 types of lymphoma. Unlike leukemia lymphoma is a solid tumor Generally speaking (this is by no means 100% true) lymphoma develops in the lymphatic system Think lymph nodes and spleen Leukemia develops in the bone marrow The two main classifications of lymphoma […]

The post S2 E079 Lymphoma and an important tactic for the PANCE appeared first on Physician Assistant Exam Review.

S2 E078 Leukemia Jun 09, 2021

Show notes

Leukemia Leukemia is a disease characterized by the overproduction of a particular type of blood cell. This process often inhibits the production of normal blood cells These leukemia cells do not function as proper cells Leukemia does not form a solid tumor. Rather it produces blood cells which may infiltrate tissue. Leukemic cells have unusually […]

The post S2 E078 Leukemia appeared first on Physician Assistant Exam Review.

S2 E077 Hemolytic Anemias May 25, 2021

Show notes

Sickle Cell Anemia Genetic Pattern Autosomal recessive Homozygote inheritance of Hemoglobin S (HbS) Predominantly seen in the African American population Oxygenated HbS does not dissolve well and forms a gel that distorts the shape of the RBC into a sickle. This makes the cells “sticky” and less flexible leading to clogging of small blood vessels. […]

The post S2 E077 Hemolytic Anemias appeared first on Physician Assistant Exam Review.

S2 E076 Macrocytic Anemia May 11, 2021

Show notes

Macrocytic Anemia Macrocytic anemias produce strange dysfunctional blood cells. This will result in some hemolysis and progress to splenic dysfunction as the spleen becomes overloaded. Howell-Jolly bodies are DNA remnants seen with a macrocytic anemia or a damaged spleen. You will find them in B12 deficiency anemia, folate deficient anemia, sickle cell anemia and celiac […]

The post S2 E076 Macrocytic Anemia appeared first on Physician Assistant Exam Review.

S2 E075 Microcytic Anemia and a Better Way to Remember Apr 28, 2021

Show notes

Anemia Anemia means low RBC or Hgb count. A patient could be bleeding out and have a low Hgb or they could have a dietary deficiency. Anemia is a starting place. As we get more detailed and more specific we can get a more clear diagnosis and treatment plan. One of the easiest places to […]

The post S2 E075 Microcytic Anemia and a Better Way to Remember appeared first on Physician Assistant Exam Review.

S2 E074 Red Blood Cells Apr 13, 2021

Show notes

Red Blood Cells Priming Questions What are the four polypeptide chains that make up hemoglobin? Define polycythemia What does MCV stand for and what does it mean? Define hemolysis. Red Blood Cells Simplified The specific shape of a RBC gives it an increased surface area for better gas exchange and flexibility for fitting into tiny […]

The post S2 E074 Red Blood Cells appeared first on Physician Assistant Exam Review.

S2 E073 Hematology Overview Mar 30, 2021

Show notes

Red Blood cells, White blood cells, Platelets Our Three Basic Problems We either have to many We don’t have enough What’s being made isn’t working correctly Cytoses Polycythemia – to many RBC’s Thrombocytosis -to many Platelets Cytopenias Anemia – low RBC Leukopenia -low WBC Coagulation disorders Clotting factor disorders – messed up clotting factors Thrombocytopenias […]

The post S2 E073 Hematology Overview appeared first on Physician Assistant Exam Review.

Our TOPPODCAST Picks

Follow Us

Stay Connected

Physician Assistant Exam Review

Related Podcasts

Links

Stay Connected