PharmaTalkRadio

Latest Episodes:

Remote Monitoring for Clinical Research in the Digital Age Sep 18, 2020

Show notes

In this PharmaTalk podcast, MaryAnne Rizk, PhD, of IQVIA, leads a multi-perspective panel discussion on monitoring in the digital age as data becomes the new currency. Together they discuss how AI and ML are empowering sponsors and sites to predict risk before it happens, how modernization is expanding remote monitoring capabilities and the waterfall impact of that on analytical roles, and how this technology can be leveraged to benefit patient engagement and data standards. Dr Rizk went into deeper detail on this subject at the 2020 DPHARM: Disruptive Innovations conference. Moderator: MaryAnne Rizk, Ph.D. - SVP Digital R&D, IQVIA Guests: Michael Mittleman – Patient Advocate Ray Reilly – VP, Clinical Operations, TG TherapeuticsRajneesh Patil – Head, Process, Technology & Analytics, IQVIA For more information about PharmaTalk podcasts, visit theconferenceforum.org. A special thanks to the team at IQVIA for their support in presenting this podcast.

Solving for the Patient Retention Problem in Clinical Research Sep 09, 2020

Show notes

In this PharmaTalk episode, Thomas Klein, founder and CEO of Be the Partner, discusses how to implement new retention and engagement methods to stop patients from "vanishing" in the clinical trial process. Mr Klein sat down with PharmaTalk's Danny McCarthy to discuss potential solutions, including transparency of data, increasing communication before, during and after trials, and truly making patients "partners" in the research. Mr Klein presented at the 2020 Patients as Partners virtual conference. Guest: Thomas Klein is the CEO and founder of Be the Partner, a technology company that is focused on how patients can use their health data to improve outcomes for themselves and others around the world. For more information go to or contact www.bethepartner.com.

IO Combinations 360° Overview in 7 Minutes Sep 08, 2020

Show notes

Kate Woda, IO Combinations 360° Conference Director, gives a 7 minute overview on what you can expect at the 5th annual IO Combinations 360° conference taking place October 1-2 virtually. 2020 Key Topics: Discovery / Preclinical ScienceBispecificsTranslational Science & BiomarkersNext Generation Cell TherapyClinical DevelopmentsOperationalizing CombinationsBusiness AspectsEmerging Technologies Keynotes Include: Ronald Germain, MD, PhD, National Institutes of HealthSteve Hamilton, Melanoma Cancer SurvivorEdward Tenthoff, Piper Sandler & Co. 2020 Strategic Leadership: Dan Chen, MD, PhD, IGM BiosciencesAxel Hoos, MD, PhD, GSKAlexandra Snyder, MD, Merck Research LabsOmid Hamid, MD, The Angeles Clinic and Research InstituteRaluca Verona, PhD, Janssen R&DJames Gulley, MD, PhD, National Cancer Institute, NIHTheresa LaVallee, PhD, Parker Institute for Cancer ImmunotherapyRoy Baynes, MD, PhD, Merck Research LabsMichael Kalos, PhD, ArsenalBio Learn more about the upcoming IO Combinations 360° virtual conference at www.iocombinations360.com

Enabling Clinical Trial Continuity with Live Video Visits Sep 08, 2020

Show notes

In this PharmaTalk podcast, Kelly McKee of Medidata leads a multi-perspective panel discussion on the challenges and opportunities of adopting a decentralized model for clinical trials and ensuring clinical trial continuity with live video visits. Together they discuss lessons learned from the rapid adoption of technologies to allow for more decentralized trials, how incorporating multiple perspectives highlights areas of growth when utilizing a decentralized approach, and the possibility of hybrid trials becoming the new normal for the near future. Host: Kelly McKee is the Senior Director of Patient Recruitment and Registries at Medidata Guests: Anne Marie Mercurio is a patient and research advocate and caregiver. Rosamund Round is Vice President of PAREXEL’s Patient Innovation Center. Jeff Kingsley, DO, is the founder and CEO of IACT Health. For more information about PharmaTalk podcasts, visit theconferenceforum.org. A special thanks to the team at Medidata for their support in presenting this podcast.

Roche's Dr Barbara Lueckel's Opening Remarks and the 2018 Year in Review Aug 26, 2020

Show notes

Chair of the Partnership Opportunities in Drug Delivery (PODD) event, Dr Barbara Lueckel, Global Head of Research Technologies Partnering at Roche, presents an annual year-in-review of the drug delivery landscape from 2018. Dr Lueckel’s opening remarks are a highlight of PODD every year, and we’re excited to have her return as program chair for the 2020 event, taking place virtually October 8-9, 2020. About Dr Lueckel: Barbara is the Global Head of Research Technologies Partnering and a member of the Roche Pharma Partnering leadership team since May 2019. In her role she is working closely with the two research and early development organizations at Genentech and Roche (gRED and pRED) to identify transformative science developed by biotechs around the globe and help set up partnerships with such biotechs to enable novel discovery programs with the goal to increase the number of medicines impacting patients’ lives. Prior to Roche, Barbara worked at Novartis for ten years both on formulation development of poorly soluble molecules as well as on evaluations of reformulation opportunities as potential line extensions based on external drug delivery technologies. She is trained as a pharmacist with a PhD from the University of Basel.

How a Gene Therapy for Duchenne Muscular Dystrophy Came to Be Aug 25, 2020

Show notes

This podcast dives into the history of creating a gene therapeutic for Duchenne Muscular Dystrophy. Dr Richard Jude Samulski has been studying gene therapy and the use of the AAV vector for decades. Recently, preliminary results from Pfizer were published on a small gene therapy trial for Duchenne Muscular Dystrophy with promising results, and Pfizer is scheduling a larger trial for later this year. That gene therapy originated from Dr Samulski work and from AskBio, and uses an adeno-associated virus to carry a healthy copy of the dystrophin gene; the virus was injected into boys with DMD, broke into their muscle cells, and replaced their non-working gene. Dr Samulski sat down with PharmaTalk's Danny McCarthy to discuss the process of creating an AAV vector to carry the gene therapeutic, the mechanisms of the therapy in DMD and what the future of the gene therapy landscape might look like. Guest: R. Jude Samulski, PhD, is President, Chief Scientific Officer and Co-Founder of Asklepios BioPharmaceutical and Professor of Pharmacology in the UNC School of Medicine. Dr Samulski has worked with AAV for 40 years, and for 25 years, he was director of the University of North Carolina Gene Therapy Center. Asklepios Bio's Chief Medical Officer, Martin Childers, DO, PhD, will be speaking at the Chief Medical Officer 360˚ summit, October 26-27, 2020, virtually.

How a Covid-19 Research Study was Formed with Oracle, Javara and Wake Forest Jul 27, 2020

Show notes

This podcast tells the story of how a community-based COVID-19 research study was formed from a partnership between Oracle Health Sciences, Javara Research and Wake Forest Baptist Health, with the end goal of using regional infection patterns to understand the virus and develop strategies to contain it. Kathy Vandebelt of Oracle sat down to talk about the partnership enhanced Oracle's Therapeutic Learning System, which was set up to track how physicians were treating individuals infected with the virus and making the information available for others to learn from, for a real-world surveillance study. The collaboration resulted in the addition of a new component for the platform, the Patient Monitoring System, which aided in collecting daily information across a large population of participants and offering them the potential to participate in regular testing. That technology is being used for multiple studies on local, regional, national and now global levels. In the conversation, Ms Vandebelt also discusses the unexpected collaborations that emerged across the research spectrum as a result of the pandemic, how the Oracle team adapted their technology to keep pace with an evolving on-the-ground situation, and how clinical operations might benefit from adopting more decentralized measures, ultimately giving patients more choices. Guest: Kathy Vandebelt is Global Head of Clinical Innovation for Oracle Health Sciences, where she uses the power of technology to introduce new experiences and expectations to make the clinical research ecosystem better for patients, healthcare providers, sponsors and regulators. For more information about Oracle's COVID-19 response, visit Oracle.com. For more information about PharmaTalk Radio podcasts, go to theconferenceforum.org.

IO Biomarker Discovery & Personalized Cancer Therapy Development with Personalis Jun 19, 2020

Show notes

PharmaTalk Radio’s Kate Woda welcomes guest, Erin Newburn, Director and Field Applications Scientist at Personalis on the topic of IO Biomarker Discovery and Personalized Cancer Therapy and how Personalis is enabling this. Guest Bio: Erin Newburn, PhD joined Personalis as a Field Applications Scientist in 2013 with over 12 years of research experience in the areas of molecular biology, genetics, and biotechnology. As the Director of the Field Applications Scientist team, Dr Newburn’s group has the responsibility of providing both pre- and post-sale scientific and technical support for the Personalis ImmunoID NeXT Cancer Portfolio. Dr Newburn completed her postdoctoral training at the National Institute of Mental Health (NIMH) investigating candidate susceptibility genes for major psychiatric illnesses. Dr Newburn received her PhD from the Ohio State University in Integrated Biomedical Science as a Presidential Fellow. Information about Personalis, visit www.Personalis.com Information about upcoming conferences and podcasts on medicine development, visit theconferenceforum.org.

The Impact of COVID-19 on Clinical Trials: Where are We? And Where are We Going? Jun 18, 2020

Show notes

As the country goes through the phases of reopening, what does that mean for the patient and site experience in clinical trials? PharmaTalkRadio’s Valerie Bowling discusses the future of clinical trials with Dr Ray Dorsey, Matt Kibby and Craig Lipset. Together they address lessons learned from the rapid adoption of technologies to allow for more decentralized trials and their impact on study participation design moving forward, what sponsors can do to set themselves up for success, and the possibility of hybrid trials becoming the new normal for the near future. Guests: Ray Dorsey, MD, is the David M. Levy Professor of Neurology and Director of the Center for Health & Technology at the University of Rochester. Matt Kibby is President, Principal of BBK Worldwide Craig Lipset is the founder of Clinical Innovation Partners and the former Head of Clinical Innovation and Venture Partner at Pfizer You can find all three of our guests speaking at either the upcoming Mobile in Clinical Trials conference or the 10th annual DPHARM conference virtually over September 21st-23rd. For more information about these conferences and other podcasts, visit theconferenceforum.org. For more information about BBK, visit BBKworldwide.com Dr Dorsey's book on Ending Parkinson's Disease can be found on Amazon. You can keep up with Craig Lipset at twitter.com/craiglipset A special thanks to the team at BBK for their support in presenting this podcast.

7th Annual Mobile in Clinical Trials Overview in Under 5 Minutes Jun 18, 2020

Show notes

In this podcast, Mark Scherzer, producer of Mobile in Clinical Trials gives an overview of what to expect at the 2020 virtual conference. The 7th annual meeting is co-chaired by Bayer's Michelle Shogren and Healthmode's Dan Karlin and reports on the latest progress in applying mobile-digital tools and patient-facing technologies for flexibility while connecting and empowering patients. It will feature collaborative, experience-based case studies to help R&D move faster to provide more choices for patients and investigators while obtaining better outcomes in drug development.

Our TOPPODCAST Picks

Follow Us

Stay Connected

Related Podcasts

Links

Stay Connected