Stay ConnectedThe Nature Podcast brings you the best stories from the world of science each week. We cover everything from astronomy to zoology, highlighting the most exciting research from each issue of the Nature journal. We meet the scientists behind the results and provide in-depth analysis from Nature‘s award-winning journalists.
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Ivermectin is a cheap, widely available, anti-parasitic drug that has been proposed by many as a possible treatment for COVID-19. Dozens of trials have been started, but results have been far from clear, with inconsistent results further confused by high profile paper retractions. Nonetheless many countries have recommended the use of Ivermectin, despite WHO advice to the contrary.
Now a group of researchers have found suspect data in another influential paper which claimed a Ivermectin caused a 90% reduction in fatality. The paper, published at the end of 2020, has since been withdrawn pending investigation. In this episode of Coronapod we ask what this might mean for Ivermectin, and what's next for the controversial drug.
Correction: at 2:53 when discussing two discredited studies, we mistakenly say that the papers say "both drugs worked really well". In fact, this retracted study from the Lancet claimed that the drug hydroxychloroquine caused harm. We apologise for any confusion. More information on the scandal surrounding these papers can be found here.
News:Flawed ivermectin preprint highlights challenges of COVID drug studies
News: Latin America’s embrace of an unproven COVID treatment is hindering drug trials
Coronapod: The Surgisphere scandal that rocked coronavirus drug research
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Satellite imaging has shown population increases are 10x higher in flood prone areas than previously thought, and a new way to introduce fairness into a democratic process.
In this episode:
00:47 Calculating how many people are at risk of floods.
Researchers have used satellite imagery to estimate the number of people living in flood-prone regions. They suggest that the percentage of people exposed to floods has increased 10 times more than previously thought, and with climate change that number is only set to climb.
Research Article: Tellman et al.
News and Views: The fraction of the global population at risk of floods is growing
09:41 Research Highlights
People are happy to be selfish towards a crowd, but generous to an individual; and how wildfire smoke affects clouds’ brightness.
Research Highlight: ‘Robber’ experiment tests generosity — with sobering results
Research Highlight: Wildfire smoke creates brighter clouds — and weather changes
12:01 Making democracy fairer
Citizens’ assemblies are small groups of people invited to come together to help inform and affect policy decisions. But deciding who is in these groups is a mathematical challenge — the process needs to be random, but still reflect social demographics. This week, researchers describe a new algorithm that could offer a solution.
Research article: Flanigan et al.
News and Views: A bridge across the democracy–expertise divide
20:04 Briefing Chat
We discuss some highlights from the Nature Briefing. This time, how ships could spread a deadly coral disease, and research shows that female scientists are less likely to be cited in elite medical journals.
The Guardian: Deadly coral disease sweeping Caribbean linked to water from ships
Nature News: Fewer citations for female authors of medical research
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Researchers debate whether an ancient fossil is the oldest animal yet discovered, and a new way to eavesdrop on glaciers.
In this episode:
01:04 Early sponge
This week in Nature, a researcher claims to have found a fossil sponge from 890-million-years-ago. If confirmed, this would be more than 300-million-years older than the earliest uncontested animal fossils but not all palaeontologists are convinced.
Research Article: Turner
10:13 Research Highlights
A caffeine buzz appears to improve bees’ memory, and reconstructing an Iron Age man’s final meal.
Research Highlight: A caffeine buzz gives bees flower power
Research Highlight: The guts of a ‘bog body’ reveal sacrificed man’s final meal
12:34 Eavesdropping on a glacier’s base
We hear about one researcher’s unorthodox attempt to listen in to the seismic-whisper at the foot of a Greenland glacier – a method that might reveal more about conditions under these enormous blocks of ice.
Research Article: Podolskiy et al.
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Archaeological evidence shows that ancient people ate carbs, long before domesticated crops.
While the idea that early humans subsisted mainly on meat persists, archaeologists are increasingly understanding that ancient people have actually long been in love with carbs, even before the advent of agriculture.
This is an audio version of our feature: How ancient people fell in love with bread, beer and other carbs
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Early in 2021 the United Kingdom, along with several other countries, allowed mass gatherings as part of a series of controlled studies aimed at better understanding the role events could play in the pandemic. The goal was to inform policy - however early results have provided limited data on viral transmission.
As the Olympic games kick off in Tokyo, we delve into the research, asking what the limitations have been, if more data will become available and whether policy makers are likely to take the findings into account in the future.
News: COVID and mass sport events: early studies yield limited insights
News: Why England’s COVID ‘freedom day’ alarms researchers
Podcast: Coronapod: does England's COVID strategy risk breeding deadly variants?
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Funding for gun violence research in the US returns after a 20-year federal hiatus, and the glass sponges that can manipulate ocean currents.
In this episode:
00:45 Gun violence research is rebooted
For 20 years there has been no federally-funded research on gun violence in the US. In 2019, $25 million a year was allocated for this work. We speak to some of the researchers that are using these funds, and the questions they are trying to answer about gun violence.
News Feature: Gun violence is surging — researchers finally have the money to ask why
Podcast: Stick to the science
09:21 Research Highlights
Strategic laziness and yak dung help pikas survive harsh winters, and how food gets wasted in China’s supply chains.
Research Highlight: Pikas in high places have a winter-time treat: yak poo
Research Highlight: China wastes almost 30% of its food
11:40 How a sea sponge controls ocean currents
Venus’ flower baskets are marine sponges that live at the bottom of the Pacific Ocean. These sponges have an unusual glass skeleton that helps them gather food, and even appears to control ocean currents.
Research Article: Falcucci et al.
News and Views: Fluid flow through a deep-sea sponge could inspire engineering designs
18:55 Briefing Chat
We discuss some highlights from the Nature Briefing. This time, investment in non-human primate facilities, and the European Union's latest climate plan.
Nature News: The US is boosting funding for research monkeys in the wake of COVID
BBC News: EU unveils sweeping climate change plan
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The UK government has announced that virtually all COVID restrictions will be removed in England on Monday 18th July. This will do away with social distancing requirements, allow businesses to re-open to full capacity and remove legal mask mandates. This decision comes, however, amidst soaring infections rates in the country, driven by the delta variant.
Now scientists are questioning the wisdom of this policy and asking whether the combination of high transmission and a partially vaccinated population could provide the perfect breeding ground for vaccine-resistant variants - a possibility which could have devastating global consequences.
News: Why England’s COVID ‘freedom day’ alarms researchers
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Why heat waves disproportionately impact minorities in US cities, and the researcher that critiqued his whole career on Twitter.
In this episode:
00:45 How heat waves kill unequally
Researchers are beginning to unpick how historic discrimination in city planning is making the recent heat waves in North America more deadly for some than others.
News Feature: Racism is magnifying the deadly impact of rising city heat
11:59 Research Highlights
A graphene layer can protect paintings from age, and a new and endangered species of ‘fairy lantern’.
Research Highlight: A graphene cloak keeps artworks’ colours ageles
Research Highlight: Newfound ‘fairy lantern’ could soon be snuffed out forever
14:25 Self-criticism
When researcher Nick Holmes decided to criticise his past papers, in 57 tweets, he found the reflection enlightening. Now he’s encouraging other researchers to self-criticise, to help speed scientific progress.
World View: I critiqued my past papers on social media — here’s what I learnt
20:53 Briefing Chat
We discuss some highlights from the Nature Briefing. This time, Richard Branson’s commercial space flight, and the Maori perspective on Antarctic conservation.
The Washington Post: Richard Branson and his Virgin Galactic crew are safely back from space, ushering in a new era
The New York Times: The Maori Vision of Antarctica’s Future (intermittent paywall)
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For much of the pandemic, the greatest burden of disease has been felt by older generations. But now, for the first time, vaccine roll outs are starting to skew the average age of those infections towards the young. This has led many researchers to ask what this might mean for the future of the pandemic. In this episode of Coronapod we discuss what we know and what we don't know about this change in the demographic profile of COVID infections. We ask how this might impact global vaccination efforts, disease transmission and the health and wellbeing of young people.
News: Will COVID become a disease of the young?
News: How kids’ immune systems can evade COVID
Podcast: Coronapod: counting the cost of long COVID
Podcast: Coronapod: Kids and COVID vaccines
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Addressing the problem of sudden food scarcity in US cities, and the up-and-coming field of computational social science.
In this episode:
00:45 Food shocks
Climate change, the COVID-19 pandemic, and geopolitical crises can cause food shortages. To tackle this issue, Alfonso Mejia and colleagues have modelled how to best mitigate these food shocks in US cities. Alfonso tells us about the new analyses and what steps cities could take in the future.
Research Article: Gomez et al.
News and Views: How to buffer against an urban food shortage
06:07 Research Highlights
A tiny lattice can withstand the impacts of projectiles at twice the speed of sound, and the neurons that allow humans to perceive time.
Research Highlight: Supersonic strikes leave just a dent in this super-light material
Research Highlight: The ‘time neurons’ that help the brain keep track
08:25 Computational Social Science
Big data is transforming research, and social science is no exception. This week, Nature is running a special issue on ‘computational social science’. We catch up with some of the editors involved to find out more about this up-and-coming field.
Collections: Computational Social Science
19:27 Briefing Chat
We discuss some highlights from the Nature Briefing. This time, discovering the dazzling diversity of viruses, and how China eradicated malaria.
Nature News Feature: Beyond coronavirus: the virus discoveries transforming biology
Science: It’s official: China has eliminated malaria
Nature Videos
Diabetes in sub-Saharan Africa
Why leaky pipes can be better for moving water
The artificial pancreas: a bridge to a cure
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