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    Natural Sciences

    Loh Down on Science: Special Pandemic Edition

    The Loh Down on Science: Special Pandemic Edition explores the science and history of pandemics (appropriate for middle school and up). Each week, fascinating new three-minute modules are reported by science writers from the Loh Down on Science “Hive.” Subjects include: global crises’ unexpected “silver linings” (i.e. technological innovations), what Isaac Newton did during HIS 1600’s college quarantine, the science of soap, COVID-19’s surprising impacts on climate change, and Folding@home, a cool new project seeking to model a coronavirus cure with the help of our home computers (it worked for Ebola!).

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    Copyright: © Copyright 2020 Loh Down on Science: Special Pandemic Edition

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    Latest Episodes:
    Pandemic Pets May 10, 2020
    Show notes

    Cat got your quarantine? As people are stuck in the coronavirus induced self-quarantine, many pet owners have started noticing a shift in their pet’s behavior. Why are they being weird? They don’t need to worry about paying the bills! Well, we may be the culprits of their peculiarities. Research has found that anxious, aggressive, and fearful cats reflect the personality traits of neurotic owners. Dogs are also more responsive to their owners that are stressed than those that are calm. As we learn to navigate the stressful pandemic, we must remember that our pets are empathetic to our emotions. Next time we notice our pets acting strange, maybe we need to self-reflect!

    Written and reported by Bahareh Sorouri.

    References:

    1. Carballo, F., Dzik, V., Freidin, E. et al. Do dogs rescue their owners from a stressful situation? A behavioral and physiological assessment. Anim Cogn 23, 389–403 (2020).
    2. Finka LR, Ward J, Farnworth MJ, Mills DS (2019) Owner personality and the wellbeing of their cats share parallels with the parent-child relationship. PLoS ONE 14(2): e0211862.
    3. Waters, Michael. Why your pet is acting like a weirdo during quarantine, explained by animal behaviorists. Vox. April 24, 2020.

    Labs in Translation May 10, 2020
    Show notes

    Mistranslation? Awkward. Surprisingly, it was a classic mistranslation after the Franco-Prussion War that prompted the acceptance of biosafety. Now, we keep dangerous pathogens locked up tight! And their identities might surprise you…


    Depending on the biosafety level, lab techs might wear special ventilation suits or even decontaminate their clothes. But these extreme measures are only used against the world’s most dangerous viruses and bacteria. Shockingly, protocols for the infamous new coronavirus aren’t as strict as they are for dangerous space rocks!

    Written and recorded by Brenna Biggs.

    References:

    1. Ahern, H. Biosafety Practices and Procedures for the Microbiology Laboratory. Milne Library (Retrieved 2020).

    2. Biosafety Labs: What Are Biosafety Labs? National Institute of Allergy and Infectious Diseases (2011).

    3. Biosafety worldwide: Historical Background. Belgian Safety Server (2020).

    4. Ullmann, A. Pasteur-Koch: Distinctive Ways of Thinking about Infectious Diseases. Microbe Magazine (2007).

    5. What Is considered a Level Four Disease? Aftermath (2017).


    Sanitation Lamentation May 04, 2020
    Show notes

    Humans have made remarkable progress in eliminating diseases. Diseases that were once very common are no longer common today. For example, fecal-oral route diseases once plagued nearly every society in history. These diseases only go away when people practice good hygiene. But the necessary technologies need to be available, and practices need to be taught. A shift in how society thinks is necessary. In this episode we talk about historian Dr. Alex Bay who studies the history of public health in Japan.


    Free Play May 04, 2020
    Show notes

    Modern childhood in America is different. Children spend most of their time in structured activities: School, sports, and mountains of homework. No time for biking around the neighborhood. Until now. School is out. What will children do with all of that time? Bounce a ball? Take a walk around the block? Are there any benefits for children that spend time in these unstructured activities?

    Written and reported by Emily Sarah Sumner, PhD

    REFERENCES

    Barker, Jane E., Andrei D. Semenov, Laura Michaelson, Lindsay S. Provan, Hannah R. Snyder, and Yuko Munakata. "Less-structured time in children's daily lives predicts self-directed executive functioning." Frontiers in psychology 5 (2014): 593.


    Gray, Peter. Free to learn: Why unleashing the instinct to play will make our children happier, more self-reliant, and better students for life. Basic Books, 2013.


    Twenge, Jean M., A. Bell Cooper, Thomas E. Joiner, Mary E. Duffy, and Sarah G. Binau. "Age, period, and cohort trends in mood disorder indicators and suicide-related outcomes in a nationally representative dataset, 2005–2017." Journal of Abnormal Psychology (2019).


    Thomas, Ashley, P. Stanford, and Barbara Sarnecka. "No child left alone: Moral judgments about parents affect estimates of risk to children." Collabra: Psychology 2, no. 1 (2016).


    https://www.cnn.com/2020/04/27/health/children-mental-health-quarantine-coronavirus-wellness/index.html


    http://letgrow.org/

    https://bigthink.com


    Double Corona May 04, 2020
    Show notes

    Recovered from the new coronavirus? Congratulations! It’s safe for you to go out again! Or is it?

    This is Stella Moon with the Loh Down on Science: Special Pandemic Edition.

    In mid-April, South Korea reported some surprising results. Within a month of recovery, around two percent of those infected tested positive for the virus for the second time! These disappointed survivors had to return to quarantine. And their families were monitored for fourteen days.

    Then. . . another SURPRISE! None of the families got sick again!

    Wait…? So can we go out or not?

    It depends… on whether it’s a “Reactivation”... or “Reinfection.”

    In a “reactivation,” hidden and inactive, remnants of the virus mount a second offensive! But no worries! Our body has special forces, called Antibodies!

    Antibodies are proteins, which are building blocks of our body, produced in our blood. Their superpower to “neutralize” makes the attacking virus inactive. How? By looking at the antigen, the shape of the virus, antibodies bind with the virus. Our antibodies already know these antigens. Chance of winning: good. Infecting others? No.

    In the case of a “reinfection” though, things are different. The virus army attacking us are new forces from outside. Reinfection is impossible if we still had the antibodies. But, the body stopped producing the antibodies, because it thought the battle was over. We’re no longer immune! Chance of winning? Unknown. Infecting others? Probably!

    What about their families? Despite being very close to each other, none of them caught Covid for the second time! YAY! But WHY?

    It could be a virus reactivation, rather than a reinfection. Still confused? Let’s look at a well-known example of virus reactivation: chickenpox.

    We’ve all heard of YOCO, “You only get chickenpox once”. But the virus causing chickenpox can reactivate, and cause shingles. Shingles and chickenpox have different symptoms, and importantly shingles are not contagious. Why? Reactivation is possible, but reinfection? Impossible!

    Let’s be careful though. There are many unanswered questions about Covid.

    You want to go back to work, but don’t have the antibody army? Well, how about BTS ARMY instead?

    Written and reported by Stella Moon

    References

    Can You Be Re-Infected After Recovering From Coronavirus? Here's What We Know About COVID-19 Immunity.

    Chickenpox versus Shingles -- What’s the Difference?

    Tests in recovered patients found false positives, not reinfections, experts say


    Spiked Sanitizers May 03, 2020
    Show notes

    Alcohol just refers to a type of molecule. And though it means an array of different cocktails for us, in large enough amounts it spells death to viruses like the coronavirus. Learn some of the chemistry behind why alcohol kills viruses and remember to check that hand sanitizers are at least 60% alcohol!

    For more details, please reference the CDC. The following links here and here offer a deeper insight into the chemistry of hand sanitizers. And finally, Parade is keeping a running list of local disteries who are producing hand sanitizers.

    Written and reported by Kellen Kartub, Ph.D.


    Easy as CDC May 03, 2020
    Show notes

    Mosquitoes… they do more than ruin a nice day by the river. These winged brutes cause dozens of diseases from West Nile virus to malaria. During WWII, President Roosevelt had enough. He formed a special task force to rid the nation of this infectious threat… the CDC.

    Armed with insecticide sprayers, they sprayed hundreds of military bases—and later, millions of households!—throughout the southeastern United States. The CDC has expanded (and of course, iterated through many name changes) to study and prevent the world’s most deadly diseases. Now, we don’t just rely on them to swat mosquitoes, we depend on them to lead us through global pandemics.

    Written and reported by Brenna Biggs.

    References:

    1. Our History. CDC (2019).

    2. Parascandola, J. From MCWA to CDC—origins of the Centers for Disease Control and Prevention. Public Health Reports (1996).

    3. Biosafety in Microbiological and Biomedical Laboratories, 5th Edition. CDC (2009).


    Uncertainly Certain Apr 26, 2020
    Show notes

    Scientists in the media often have uncertainties around talking about experimental uncertainties. Why? Because they worry about trust! Error and uncertainty has a specific meaning in science. It gives us hard numbers on how much we can trust a measurement. But, the unfamiliar may believe it means mistakes and incompetence. In order to avoid any loss in public trust in science itself, scientists may not always talk about it. Are these fears grounded in reality? An important new study on uncertainty and trust certainly sheds light on the topic.

    References

    Anne Marthe van der Bles, Sander van der Linden, Alexandra L. J. Freeman, David J. Spiegelhalter. The effects of communicating uncertainty on public trust in facts and numbers. PNAS April 7, 2020 117 (14) 7672-7683; first published March 23, 2020 https://doi.org/10.1073/pnas.1913678117


    The Tale of Lady Montagu Apr 26, 2020
    Show notes

    Smallpox… the word sounds harmless enough, but this “speckled monster” was the scourge of Western Europe throughout the 1700s. Why did it disappear? The credit belongs to a fiery 18th-century feminist.

    Lady Mary Wortley Montagu rebelled against everything—her father, societal norms, and smallpox. After catching—and recovering from—the disease, she vowed to protect her children from living the same horror. But she had to face intercontinental travel, a pus-based economy, and a stubborn kingdom to do it. If she succeeded, Western Europe could be rid of smallpox forever.

    Written and reported by Brenna Biggs.

    References:

    1. Hager, T. How One Daring Woman Introduced the Idea of Smallpox Inoculation to England. Time (2019).

    2. Montagu, L. M. W. Letters of the Right Honourable Lady M--y W---y M---e: Written During Her Travels in Europe, Asia and Africa, to Persons of Distinction, Men of Letters, &c. in Different Parts of Europe. Which Contain, Among Other Curious Relations, Accounts of the Policy and Manners of The Turks.... Complete in One Volume. M. Cooper (1779).

    3. Smallpox: A Great and Terrible Scourge. National Institutes of Health: U.S. Library of Medicine (2013).

    4. Riedel, S. Edward Jenner and the history of smallpox and vaccination. Baylor University Medical Center Proceedings (2005).


    Of Scientists and Sundews Apr 26, 2020
    Show notes

    When not in a pandemic, Professor Rachel Martin studies the interesting enzymes in carnivorous plants. When she realized that coronavirus relies on the same type of enzyme, she got to thinking about how she could use her expertise to help the world. Fast forward a few weeks, and this project has expanded to a campus-wide collaboration including professors Carter Butts, Doug Tobias, Andy Borovik, Vy Dong, Liz Jarvo, James Nowick, and Jenn Prescher. The team hopes to design a drug that will stop key coronavirus enzymes from functioning, preventing the virus from reproducing.

    You can follow Rachel Martin @rachelmartin the Martin lab @martinlabuci.
    For more research, you can follow @UCIChemistry or @UCIPhysSci.


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