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Latest Episodes:

158: Joint Infections PCR Panel Oct 03, 2024

Show notes

Are you familiar with the BioFire system? If you work in microbiology you probably are. How about a joint infections panel for this system? In this episode Dr. Angelica Moran and Jekzaly Arellano join the podcast to talk about a study they did evaluating this panel. Why are joint infections difficult to diagnose? Tune in to learn more.

Link to article: https://journals.asm.org/doi/10.1128/jcm.00182-24

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157: Lactobacillus Sep 26, 2024

Show notes

This week Luis continues going over gram-positive rods: this time Lactobacillus. What is the morphology of Lactobacillus? Biochemicals? Which species are typically seen in humans? Is it pathogenic or normal flora? What about susceptibilities? All great questions. Tune in to find out about this genera.

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156: Actinotignum schaalii Sep 19, 2024

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If you work with MALDI-TOF MS and you read urine cultures, you probably have seen this organism : Actinotignum schaalii. Is this organism significant? What is the gram stain? Biochemicals? Other questions come up such as we do report it? Do we perform susceptibilities ? Tune in to learn about this emerging pathogen and get answers to all these questions.

Questions? Feedback? Send those to letstalkmicro@outlook.com

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155: ASCP: Microbiology Certifications Sep 12, 2024

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Thinking about getting certified in microbiology but not sure where to start? In this episode Luis chats with Dr. Amanda Harrington about certification options through the American Society for Clinical Pathology (ASCP).

They cover how to qualify, what the Specialist in Microbiology (SM) is all about, and even options if you haven't gone through a traditional MLS program. If you're curious about leveling up in the lab—this one's for you!

Link to certifications in Microbiology from ASCP:

https://www.ascp.org/content/board-of-certification/get-credentialed?srsltid=AfmBOoo4i6_pt4DLUEKUJmclab7AJkFp1bZlPGibNnIqLb-jgp3JGgvO#

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154: Dengue Sep 05, 2024

Show notes

Dr. Rodney Rohde returns to the podcast! This time he joins Luis to talk about dengue. You might hear reports about increases in cases in some areas, so it was a good time to talk about it. What is dengue? What type of virus it is? Vectors? Prevention? Is there a vaccine? Tune in to learn more about this virus.

Link to Dr. Rohde's dengue article: https://asm.org/articles/2024/august/dengue-is-spreading-is-warmer-weather-to-blame

More information about dengue: https://www.cdc.gov/dengue/index.html

Link to Dr. Rohde's Podcast: https://www.contagionlive.com/view/from-pathogen-to-infectious-disease-diagnosis-taking-on-potential-standard-of-care-diagnostic-opportunities

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153: Bone and Joint Infections Aug 29, 2024

Show notes

If you work in a clinical microbiology laboratory, you might have worked with bone and joint samples. In this episode we dive deeper into bone and joint infections. Luis is joined by Dr. Joan Gomez-Junyent, an Infectious Diseases physician at Hospital Del Mar in Barcelona, Spain. Dr. Gomez goes over different types of infections. What organisms are typically seen? Is there a typical treatment of choice? How about antimicrobial resistance? Tune in to hear Dr. Gomez go over these questions and more.

Questions? Feedback? Send those to letstalkmicro@outlook.com

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152: Potential antibiotics: lolamicin Aug 22, 2024

Show notes

Season 4 is here! Tune in for the first episode. Luis talks to Dr. Paul Hergenrother about lolamicin. Dr. Hergenrother is a Professor of Chemistry at the University of Illinois in Urnaba-Champaign. He was previously a guest in the podcast (fabimycin episode) and this time he returns to talk about another potential antibiotic candidate: lolamicin. What is lolamicin? What is the mechanism of action? What organisms does it have activity against? Does it affect the gut microbiota?

Link to Dr. Hergenrother's article: https://www.nature.com/articles/s41586-024-07502-0

Questions? Feedback? Send those to letstalkmicro@outlook.com

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TBT: Streptococcus anginosus group Aug 15, 2024

Show notes

Originally published in May 26, 2022, in this episode Luis continues going over beta hemolytic strep: this time Streptococcus anginosus group. What are the species that comprise this group? What is the Lancefield group? What about biochemicals and morphology? Have you heard of Streptococcus pseudoporcinus? Tune in to find out.

Questions? Feedback? Send those to letstalkmicro@outlook.com

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TBT: LPC-233: An LpxC inhibitor Aug 01, 2024

Show notes

Originally published in November 30 2023, in this episode, Dr. Pei Zhou from the Duke University School of Medicine joins the podcast and talks to Luis about LPC-233. This is a compound that shows bactericidal activity against some gram-negative rods. LPC-233 is an LpxC inhibitor. What is LpxC? How does LPC-233 works? What are some challenges of developing LpxC inhibitors? Tune in to find out.

Link to article: https://doi.org/10.1126/scitranslmed.adf5668

Questions? Feedback? Send those to letstalkmicro@outlook.com

Want to support the podcast? Here's how:

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TBT: Fabimycin: an antibiotic candidate Jul 25, 2024

Show notes

Originally published on October 13, 2022, this episode features Luis in conversation with Dr. Paul Hergenrother from the University of Illinois. Dr. Hergenrother discusses Fabimycin, an antibiotic candidate targeting gram-negative bacteria. What is Fabimycin's mechanism of action? Which bacteria is it active against? Is there any intrinsic resistance? Tune in to find out!

Link to article: https://pubs.acs.org/doi/10.1021/acscentsci.2c00598

Questions? Feedback? Send those to letstalkmicro@outlook.com

Want to support the podcast? Here's how:

Venmo: https://venmo.com/u/letstalkmicro

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