Lab Notes

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Cracking the code of addiction Oct 12, 2022

Reward is essential for life. Our brains flood with feel-good chemicals when we learn, eat, have sex. But these essential brain circuits are hijacked in drug addiction. Neuroscientists at the Allen Institute and the University of North Carolina are working to crack the biology of reward and addiction. Hear about their work and their hopes for the future of treating addiction in this episode of Lab Notes.

Bees suffer from social isolation too Aug 24, 2022

It is no secret that social isolation has major developmental consequences on humans, but what about other social creatures like bumblebees? Neuroscientist Z Yan Wang investigated how social isolation impacted young bumblebees, and it looks like they grow up to be a little ‘socially awkward.’ Dr. Wang joins Lab Notes to talk about one of her favorite social insects.

Building a consciousness meter with Christof Koch May 25, 2022

Can we put a number on human consciousness? Neuroscientist Christof Koch is leading an effort to build a consciousness meter that could have real-world applications to determine whether coma patients are in a true vegetative state. Christof joined Lab Notes to talk about the science of consciousness, what psychedelic drugs have to do with consciousness, and how this new project could one day have applications in hospitals and clinics.

Why don't we understand the brain? Mar 14, 2022

Scientists have known for centuries that the brain is the seat of human thought, but we’re still in the dark about how it works. For Brain Awareness Week 2022, Lab Notes asked four neuroscientists to get into the weeds with us about why the brain is so complicated and hard to understand. Do we have any hope of understanding our own brains?

Fire Inside: The quest to understand & prevent rheumatoid arthritis May 17, 2021

In the early '80s, Linda Sloate was a 30-year old mom raising three little kids when she became one of an estimated 20 million people worldwide living with rheumatoid arthritis (RA). It has been a 40-year struggle filled with dozens of treatments and surgeries. Today there is new hope for patients as researchers have come together for a collaborative project to uncover how RA begins – and how to stop it in its tracks.

The novelist and the scientist Mar 01, 2021

When neuroscientist Christina Kim published an important research study, her close friend, novelist Yaa Gyasi, wanted to understand more about her friend’s work, so she asked to shadow her in the lab. That experience eventually formed the basis for Gyasi’s moving novel about addiction and mental illness, Transcendent Kingdom.

Starved but unable to eat: Life with Crohn's Dec 21, 2020

Aldan Beaubien was in high school when a smorgasbord of bagels, cream cheese and apple juice left him in agony. Months later, doctors diagnosed him with Crohn's disease. Now an IT engineer at a research institute studying the disease, Aldan has new hope for better treatments or even a cure.

SCANning for coronavirus Sep 22, 2020

In the winter of 2019, a series of storms dubbed “Snowpocalypse” dumped more than 20 inches of snow on the Seattle area, forcing the closure of schools and businesses. This weather-induced social-distancing caused flu cases to plummet. What researchers learned from these snowstorms helped prepare them for the coronavirus pandemic and find what, at the time, were the earliest known cases of community spread. Their work has gone on to provide invaluable data that social distancing works to slow down deadly viruses.

Taming the Beast Aug 04, 2020

When the first U.S. COVID-19 cases began arriving at the hospital, doctors nicknamed the illness "The Beast" because of the way it attacked the body. Dr. Ryan Padgett treated several patients before he himself became infected and nearly died. How can this beast be tamed? A team of researchers in Ohio believes they have identified a set of tools that could help save lives and speed recovery times for patients like Dr. Padgett.

A face mask that detects coronavirus Apr 27, 2020

What if there were a face mask that could tell you you're infected with coronavirus before you ever show symptoms? In this episode we chat with Allen Distinguished Investigator Jim Collins from MIT and the Wyss Institute, about a wearable diagnostic that could help in the fight to trace and contain COVID-19 infections.

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