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    JACC This Week

    A weekly co-hosted podcast featuring JACC Editor-in-Chief Harlan M. Krumholz, MD, SM, FACC and JACC Senior Consulting Editor Carolyn S.P. Lam, MBBS, PhD, giving readers context on our weekly issues. Listen in as they break down the latest trends and share practical tips that are changing the way heart care works globally.

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    Copyright: © 2014 American College of Cardiology Foundation

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    Latest Episodes:
    Time to Significant Benefit of Finerenone in Patients with Heart Failure | HFSA 2024 Sep 28, 2024
    Show notes

    Michelle M Kittleson, MD, FACC, JACC Associate Editor, speaks with author Muthiah Vaduganathan, MD on his accepted paper concerning the FINEARTS trial published in JACC.


    JACC - October 1, 2024 Issue Summary Sep 23, 2024
    Show notes

    In the October 2024 issue of JACC, Dr. Valentin Fuster highlights five diverse studies addressing key topics in cardiovascular health, from surgical outcomes for congenital anomalies to the impact of patiromer on heart failure therapies. The episode underscores the importance of managing cardiovascular risk factors in chronic kidney disease and explores new insights into lipid profiles, revealing that triglyceride-rich lipoproteins may pose greater cardiovascular risks than previously understood.


    Outcomes of Patients Undergoing Surgery for Complete Vascular Rings Sep 23, 2024
    Show notes

    In this episode, Dr. Valentin Fuster highlights a groundbreaking study on surgical outcomes for complete vascular rings, revealing that 95% of children experience complete symptom resolution after comprehensive surgical interventions. The discussion emphasizes the evolution of surgical techniques at Boston Children's Hospital and the potential for fetal diagnosis to alter the natural history of this congenital anomaly.


    Patiromer Facilitates Angiotensin Inhibitor and Mineralocorticoid Antagonist Therapies in Patients with Heart Failure and Hyperkalemia Sep 23, 2024
    Show notes

    In this episode, Dr. Valentin Foster highlights a groundbreaking study published in the October 2024 issue of JACC, which explores how patiromer facilitates the effective use of angiotensin inhibitors and mineralocorticoid antagonists in heart failure patients at risk of hyperkalemia. Authored by Dr. Bertram Pete and colleagues, the research demonstrates that patiromer not only helps achieve optimal medication doses but also improves potassium management, ultimately enhancing patient outcomes in this high-risk population.


    Relationship Between Control of Cardiovascular Risk Factors and Chronic Kidney Disease Progression, Cardiovascular Disease Events, and Mortality in Chinese Adults Sep 23, 2024
    Show notes

    In this episode, Dr. Valentin Fuster discusses groundbreaking research on the interplay between cardiovascular risk factors and chronic kidney disease (CKD) progression among Chinese adults. Highlighting a study that reveals how effective management of hypertension, cholesterol, and blood glucose can significantly reduce the risks of cardiovascular events and mortality in CKD patients, the conversation emphasizes the crucial need for targeted treatment strategies to improve patient outcomes.


    Quantifying triglyceride-rich lipoprotein atherogenicity, associations with inflammation, and implications for risk assessment using non-HDL cholesterol Sep 23, 2024
    Show notes

    In this insightful discussion from the October 1, 2024 issue of JACC, researchers reveal that triglyceride-rich lipoprotein (TRL) remnants are significantly more atherogenic than LDL cholesterol, suggesting a need for updated risk assessment strategies. The study advocates for a shift towards evaluating lipoproteins on a per-particle basis, which could revolutionize the diagnosis and treatment of lipid disorders by focusing on the functional activity of these particles.


    Implantable Cardioverter Defibrillator and Resynchronization Therapy in Patients with Overt Chronic Kidney Disease: JACC State-of-the-Art Review Sep 23, 2024
    Show notes

    In this episode, Dr. Valentin Fuster discusses a comprehensive review on the challenges and considerations of using implantable cardiography devices in patients with advanced chronic kidney disease and heart failure. Highlighting key findings from Dr. Cecilia Barca's research, he explores the nuanced interplay between these conditions and device efficacy, emphasizing the need for tailored patient evaluations and future studies to improve outcomes.


    2024 ACC/AHA Key Data Elements and Definitions for Social Determinants of Health in Cardiology Sep 23, 2024
    Show notes

    In this episode, Dr. Valentin Fuster reviews a pivotal document on Social Determinants of Health (SDOH) in cardiology, highlighting their critical role in shaping health outcomes. He outlines ten key insights, emphasizing the need for standardized definitions and integration of SDOH into electronic health records to promote equitable healthcare and improve patient outcomes.


    Urinary Metal Levels and Coronary Artery Calcification: Longitudinal Evidence in the Multi-Ethnic Study of Atherosclerosis Sep 20, 2024
    Show notes

    Dr. Kaitlyn McGraw discusses her study on the relationship between urinary trace metal levels and coronary artery calcification, highlighting the role of environmental exposures in cardiovascular disease risk. The research reveals significant associations between elevated levels of metals like cadmium, tungsten, and uranium with the progression of calcification, comparable to traditional risk factors such as smoking and diabetes. Dr. McGraw emphasizes the need for integrating environmental factors into cardiovascular risk assessments and suggests policy changes to better regulate metal exposure in the population. Moderated by Khurram Nasir, MBBS, FACC.


    Interactions of Sleep Apnea with the Pathophysiology of Cardiovascular Disease, Part 1: JACC State-of-the-Art Review Sep 16, 2024
    Show notes

    In this episode, Dr. Valentin Fuster dives into a comprehensive review of obstructive sleep apnea, exploring its complex interactions with cardiovascular disease and discussing its multifaceted treatment options. The podcast unpacks how sleep apnea exacerbates cardiovascular conditions through biological pathways, examines the impact of various therapies, and considers future directions for research and clinical practice.


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