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    Science & Medicine

    Health Via Modern Nutrition with Dr. Latt Mansor

    What is the key to peak human performance? How can we achieve our ultimate metabolic potential? If you are searching for the answers to these questions, so are we. We are H.V.M.N. Join Dr. Latt Mansor, Research Lead at H.V.M.N and consultant to the world’s top performers, as he explores the limits of human optimization. What’s the evidence behind today’s hottest nutritional strategies, such as the ketogenic diet? Is there a benefit to skipping breakfast and intermittent fasting? Could the carnivore diet correct autoimmune conditions? Are there ways we can manipulate our biological “clock” and extend the human lifespan? Subscribe today and become a part of the community looking to fine-tune the human experience.

    Advertise
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    Latest Episodes:
    Ketone Esters Prevent Overtraining · Research Roundup Jun 01, 2019
    Show notes

    One of the greatest challenges of training is successfully attaining "functional overreaching". Pushing your maximal capacity results in stress that leads to beneficial adaptations...making your body stronger, faster, & better.

    What happens when you do it wrong? Aptly named, "non-functional overreaching" occurs.

    Nothing will help besides rest and recovery. In the case of "overtraining", the more serious form of overreaching, it might take months for even the most elite athletes to bounce back.

    A recent study found promising signs that ketone esters can alleviate overreaching symptoms. The researchers didn’t necessarily look at how ketones acutely influence exercise performance, but rather how consistent supplementation could affect recovery and training capacity.

    The lead researcher, Professor Peter Hespel, described the potential effect of ketones in recovery as “unseen” and “many times greater” than what he’s seen with other nutritional supplements.

    Geoffrey Woo breaks this study down, analyzes the experiment structure, and digs deep into the findings for every last nugget of applicable information.

    || Relevant Links ||

    • Ketone ester supplementation blunts overreaching symptoms during endurance training overload
    • HVMN Ketone Ester
    • Full Episode Transcription

    ----------------------------------------------------------------------------

    Check out HVMN's products for optimal metabolic health: https://www.hvmn.com/pod

    Take a short survey that will help us improve the podcast and be entered in a HVMN Ketone giveaway: https://go.hvmn.com/podcastsurvey

    We also want to hear from our listeners/viewers! Contact podcast@hvmn.com with any feedback, questions, and guest suggestions! Write a review for us on iTunes, let us know via email, and we'll send you $15 worth of HVMN Store Credit.


    Facebook Bans Millions of Keto Followers (Banting 7-Day Meal Plans) · #115 ft. Rita Venter May 27, 2019
    Show notes

    On May 14th, 2019, close to two million people on the ketogenic diet found themselves without a support system, no new meal recipes to add to their week, and really...no home.

    Banting 7-Day Meal Plans, a popular Facebook low-carb group with over 1.6 million members, was banned by the platform without warning.

    Many were in uproar and disbelief. Heated discussions around censorship, targeted attacks, and even anti-low-carb conspiracies ran amuck.

    Notable figures such as Professor Tim Noakes, Dr. Shawn Baker, Marika Sboros, and Crossfit founder Greg Glassman chimed in with their own two cents. Clashing opinions, ranging from blaming silent but powerful anti-fat industry heads to supporting Facebook’s decision because they believe the diet is unscientific, caused quite the schism. Or rather...widened the schism that’s been building as more and more adopt ketogenic/low-carb/banting lifestyles.

    After all was said and done, Facebook reinstated the group 2 days later.

    What could have caused the banning of millions in the first place?

    The creator of "Banting 7-Day Meal Plans", Rita Venter, joins this episode to walk us through the entire debacle.

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    Check out HVMN's products for optimal metabolic health: https://www.hvmn.com/pod

    Take a short survey that will help us improve the podcast and be entered in a HVMN Ketone giveaway: https://go.hvmn.com/podcastsurvey

    We also want to hear from our listeners/viewers! Contact podcast@hvmn.com with any feedback, questions, and guest suggestions! Write a review for us on iTunes, let us know via email, and we'll send you $15 worth of HVMN Store Credit.


    Hi, Fat: Challenging Carbs, Brain-body Connection, & Reversing Diabetes || #114 ft. Prof. Tim Noakes May 20, 2019
    Show notes

    Even as the fear of fat declines within the public eye, you've still probably experienced disbelief & bewilderment from co-workers, friends, or family when talking about your ketogenic lifestyle. Imagine being a high-fat, low-carbohydrate proponent as an esteemed scientist nearly two decades ago.

    With more than 750 published scientific articles & 70 marathons under his belt, Prof Tim Noakes is well-known for his many contributions to nutrition & exercise science. At the beginning of his research career, he was an advocate for a high-carb diet, which is no surprise given the medical dogma at the time, yet Noakes completely changed his mind when he learned about the value of the high-fat diet.

    Not only was he an early leader in the ketogenic movement, a stance that temporarily costed him his medical license, but Noakes actually reversed his own Type 2 diabetes through a low-carb, high-fat diet. Perhaps one of the reasons he has upheld a high reputation is his continued desire to question current scientific theory, even conclusions he first helped define. Rather than turning a blind eye and staying with his preconceived notions, Noakes follows the evidence...a model we should all aspire to have.

    In this episode, you'll discover:

    • Central governor theory: How does the brain directly influence physical performance output?
    • Ketogenic diet: Fat-fueled athleticism, improving insulin resistance, & becoming metabolically flexible
    • Noakes' commentary on the history, present, & future of nutrition science

    Save 10% off Rise, our anti-mental fatigue nootropic: https://www.hvmn.com/pod (Offer ends May 26th, 2019)

    ----------------------------------------------------------------------------

    Take a short survey that will help us improve the podcast and be entered in a HVMN Ketone giveaway: https://go.hvmn.com/podcastsurvey

    We also want to hear from our listeners/viewers! Contact podcast@hvmn.com with any feedback, questions, and guest suggestions! Write a review for us on iTunes, let us know via email, and we'll send you $15 worth of HVMN Store Credit.


    Keto Diet for Heart Health: Preventing Cardiovascular Disease || Ep. 113 ft. Dr. Ethan Weiss (Keyto) May 13, 2019
    Show notes

    How do you know if you’re following the ketogenic diet or intermittent fasting properly?

    You might feel the subjective benefits of ketosis, but quantitatively measuring ketone levels is always the most accurate (via breath, blood, or urine). Blood testing has been the standard for academic literature.

    However, practically speaking, many people aren’t going to be pricking their finger for blood to check if they’re in ketosis.

    Keyto is aiming to make the ketogenic diet more accessible through a breath meter device & phone app. Dr. Ethan Weiss, the founder of Keyto, hopes to fill that gap with the right balance of accessibility and science. Dr. Weiss, who is also a cardiologist and professor at the UCSF, is our guest this week.

    In this episode, you'll discover:

    • The ketogenic diet as a viable option for improving metabolic and cardiovascular health
    • Best practices to determine risk-factor for developing cardiovascular disease
    • The Keyto device & overall mission: Consideration of tracking ketones via acetone & how they aim to drive positive behavioral change

    Save 15% off Keyto here: www.getkeyto.com/hvmn (Offer ends May 31st, 2019. After this date, you can still save 10% off your purchase)

    ----------------------------------------------------------------------------

    Check out HVMN's products for optimal metabolic health: https://www.hvmn.com/pod

    Take a short survey that will help us improve the podcast and be entered in a HVMN Ketone giveaway: https://go.hvmn.com/podcastsurvey

    We also want to hear from our listeners/viewers! Contact podcast@hvmn.com with any feedback, questions, and guest suggestions! Write a review for us on iTunes, let us know via email, and we'll send you $15 worth of HVMN Store Credit.


    Can Ketones Reduce Anxiety? || Current Research, Mechanisms of Actions, & More May 07, 2019
    Show notes

    Before an important talk or a podcast, Dr. Rhonda Patrick drinks exogenous ketone esters. Why?

    With Dr. Patrick describing the benefit as feeling "less anxious and more in the present", there's something worth unpacking here.

    Can ketones help with anxiety? What's the state of current research & potential mechanisms of action?

    HVMN co-founder, Geoffrey Woo, details it all in this video.

    References:

    1. Inflammation study: https://www.nature.com/articles/nm.3804?foxtrotcallback=true 2. Glutmate & GABA study: https://www.ncbi.nlm.nih.gov/pubmed/9778572 3. Adenosine study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2769009/ 4. Hyperglycemia study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752923/ 5. Reduced anxiety in rats study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5138218/ 6. Reduced stress in rats study: https://www.ncbi.nlm.nih.gov/pubmed/28794421

    Learn more about HVMN Ketone: https://go.hvmn.com/ketone-podcast

    ----------------------------------------------------------------------------

    Check out HVMN's products for optimal metabolic health: https://www.hvmn.com/pod

    Take a short survey that will help us improve the podcast and be entered in a HVMN Ketone giveaway: https://go.hvmn.com/podcastsurvey

    We also want to hear from our listeners/viewers! Contact podcast@hvmn.com with any feedback, questions, and guest suggestions! Write a review for us on iTunes, let us know via email, and we'll send you $15 worth of HVMN Store Credit.


    Restoring Brain Function with Fat: An N=1 Ketones & Alzheimer's Case || #112 ft. Dr. Mary Newport May 06, 2019
    Show notes

    Fat is fuel. It’s a common saying within the keto community. Let’s focus on this in regards to the brain.

    Fat cannot directly be used by the brain, but the ketones that become converted from a fat source can. If a brain can no longer effectively use glucose, which is an observation of many neurodegenerative diseases, can we look at ketones as an alternative fuel source?

    This is the genesis of Dr. Mary Newport’s story.

    Dr. Newport’s husband, Steve Newport, battled with Alzheimer’s disease until 2016, the time of his passing. During Steve’s battle, his condition responded dramatically upon the consumption of exogenous ketones - particularly from coconut oils & ketone esters. Dr. Newport often described this response as “seeing the light coming back on in his eyes”.

    Host Geoffrey Woo & Dr. Newport discuss the proposed mechanisms of action behind her husband’s treatment with exogenous ketones, what to look for in coconut & MCT oils, & what the root causes of the rise of Alzheimer’s might be.

    Support Dr. Mary Newport's work: http://coconutketones.com/

    Learn more about HVMN Ketone Ester: https://go.hvmn.com/ketone-podcast

    ----------------------------------------------------------------------------

    Check out HVMN's products for optimal metabolic health: https://www.hvmn.com/pod

    Take a short survey that will help us improve the podcast and be entered in a HVMN Ketone giveaway: https://go.hvmn.com/podcastsurvey

    We also want to hear from our listeners/viewers! Contact podcast@hvmn.com with any feedback, questions, and guest suggestions! Write a review for us on iTunes, let us know via email, and we'll send you $15 worth of HVMN Store Credit.


    Eat a High-Fat, Low-Carb Breakfast to Stabilize Blood Sugar Levels THROUGHOUT the Entire Day || Research Roundup May 01, 2019
    Show notes

    The broad field of nutrition and health is rife with myths, misconceptions and frequently posed yet seemingly fundamental questions that we intuitively feel should have simple answers. Is a calorie a calorie? Is obesity due to eating too much or doing too little?

    Is breakfast actually the most important meal of the day?

    When looking through the lens of insulin resistance, breakfast has often been seen as a "problem" meal that leads to the largest blood sugar spikes...especially for Type 2 diabetics. This is largely due to the typical "healthy" Western breakfast foods that are high in carbohydrates: Cereal, oatmeal, toast and fruit.

    A recent study aimed to explore if eating a low-carb and high-fat meal first thing in the morning is a simple way to prevent this large insulin spike, improve glycemic control throughout the day, and reduce other diabetes complications.

    This is the paper Dr. Brianna Stubbs will be diving into in this episode of the Research Roundup.

    Referenced Study: https://academic.oup.com/ajcn/advance-article-abstract/doi/10.1093/ajcn/nqy261/5435774?redirectedFrom=fulltext

    ----------------------------------------------------------------------------

    Check out HVMN's products for optimal metabolic health: https://www.hvmn.com/pod

    Take a short survey that will help us improve the podcast and be entered in a HVMN Ketone giveaway: https://go.hvmn.com/podcastsurvey

    We also want to hear from our listeners/viewers! Contact podcast@hvmn.com with any feedback, questions, and guest suggestions! Write a review for us on iTunes, let us know via email, and we'll send you $15 worth of HVMN Store Credit.


    Metabolic Fitness: Considerations of Fasted Cardio & Muscle Growth || #111 ft. Dr. Brad Schoenfeld Apr 29, 2019
    Show notes

    Dr. Brad Schoenfeld is a natural bodybuilder turned researcher whose work focuses on the mechanisms of muscle hypertrophy. Simply put...muscle growth!

    Unlike most of our other guests, he’s more cautious on the applications of the ketogenic diet and intermittent fasting, which we wholeheartedly welcomed. This is an evidence-based conversation that unpacks various nuances around the interconnected network of metabolism and physicality.

    In this discussion, you'll discover...
    • The ketogenic diet & intermittent fasting on muscle growth and what considerations there are
    • Resistance training vs. ketogenic diet - What has the most effect on insulin resistance?
    • Discussion on protein leverage hypothesis, anabolic window, & fasted cardio

    ----------------------------------------------------------------------------

    Visit HVMN: https://www.hvmn.com/pod

    Take a short survey that will help us improve the podcast and be entered in a HVMN Ketone giveaway: https://go.hvmn.com/podcastsurvey

    We also want to hear from our listeners/viewers! Contact podcast@hvmn.com with any feedback, questions, and guest suggestions! Write a review for us on iTunes, let us know via email, and we'll send you $15 worth of HVMN Store Credit.


    Road to Boston: How I Ran a Sub-3-Hour Marathon || #110 ft. Michael Brandt Apr 23, 2019
    Show notes

    Michael Brandt, who co-founded HVMN along with our main host Geoffrey Woo, just came back from running the 2019 Boston Marathon. Especially with Boston being Michael’s second ever marathon, everyone on the HVMN team was impressed & extremely happy to hear of his 2:48 finish time. A sub 3-hour marathon is not an easy feat. On average, Michael was completing each mile in 6 minutes and 24 minutes...for 26 miles straight.

    Dr. Brianna Stubbs sits down with Michael to delve into his training structure and the running tips he’s picked up, his experience running the mother of marathons, and what motivates him to run nearly every day.

    ----------------------------------------------------------------------------

    Visit HVMN: https://www.hvmn.com/pod

    Take a short survey that will help us improve the podcast and be entered in a HVMN Ketone giveaway: https://go.hvmn.com/podcastsurvey

    We also want to hear from our listeners/viewers! Contact podcast@hvmn.com with any feedback, questions, and guest suggestions! Write a review for us on iTunes, let us know via email, and we'll send you $15 worth of HVMN Store Credit.


    mTor Signaling & Cell Growth: Targeting via Ketogenic Diet & Intermittent Fasting || #109 ft. Dr. Keith Baar Apr 18, 2019
    Show notes

    mTor…mechanistic target of rapamycin. What is it?

    We reference mTor frequently on our podcast, particularly when we discuss fasting or keto and their potential for extending health & lifespan.

    mTor is a pathway that helps controls cell growth. In the most simplest terms: When you have high mTor activation, you promote growth in the body. When you have low mTor activation, you promote repair and maintenance.

    mTor is sensitive to the nutrients we consume (especially protein and carbohydrate), so by controlling our diet, we can control mTor. This is an exciting area because a lot of people think mTor plays a role for longevity & metabolism. The ketogenic diet and intermittent fasting are natural ways to target & regulate your mTor.

    Dr. Keith Baar, a professor of Physiology at the UC Davis Medical School, is an expert on mTor and muscle growth. This is a valuable conversation for anyone interested in mTor and strategies to control it, and why non-tissue specific approaches like rapamycin might have problems.

    ----------------------------------------------------------------------------

    SAVE 50% OFF GO CUBES: https://www.hvmn.com/pod

    (offer ends April 19th, 2019)

    Take a short survey that will help us improve the podcast and be entered in a HVMN Ketone giveaway: https://go.hvmn.com/podcastsurvey

    We also want to hear from our listeners/viewers! Contact podcast@hvmn.com with any feedback, questions, and guest suggestions! Write a review for us on iTunes, let us know via email, and we'll send you $15 worth of HVMN Store Credit.


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