GEN Podcasts

Emerging Markets Collaborate to Succeed in Post-Pandemic World Apr 11, 2023

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Breathing Oxygen Back into the Biological Conversation Feb 06, 2023

As good scientific investigators, we strive to make our research more reproducible, repeatable, and translatable. These traits are ostensibly engrained in researchers from the start of their careers but often fall to the wayside in pursuit of experimental answers. Throughout this three-episode podcast series, sponsored by The Baker Company, we will weave the common thread of these essential research traits and discuss some ubiquitous techniques common to so many laboratories—focusing on areas that are often overlooked but can have a considerable impact on recapitulating physiological conditions and the efficacy of your experiments. So tune in to this first podcast where we discuss the importance of oxygen biology in common lab experiments.

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Global Single-Use Network Supports Assurance of Supply Jan 30, 2023

Single-use systems have been steadily climbing toward the top of the tools utilized by biomanufacturers for the commercial-scale production of critical therapeutic products. However, COVID-19 created an inflection point for this technology, generating an even greater demand that will shape the market for many years. Yet, with considerable demand comes the need to focus on the key aspects driving growth while discovering the appropriate solutions to the challenges that invariably arise when technologies are being developed and utilized rapidly.

This is our third and final episode of GENcast, where Dr. Ger Brophy, the Executive Vice President of Biopharma Production at Avantor, joins me. We sat down to discuss several essential facets of single-use systems and some ways to help manage risk and decrease the intricacies most often associated with single-use supply chains. Make sure you check out episode one and episode two for more in-depth discussions with Dr. Brophy.

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Resins Address Downstream Purification Concerns Jan 03, 2023

The demand for safe and efficacious biologics has accelerated exponentially in the past several years due to the tremendous success of some of the initial therapeutic offerings in this space. Yet, along with this increased demand comes the need for innovative solutions to improve downstream production workflows. For example, eliminating purification bottlenecks and improving overall yields from chromatography steps can significantly impact the final product’s cost.

In this second episode of GENcast with Executive Vice President of Biopharma Production at Avantor, Dr. Ger Brophy, we dive into some of the challenges biomanufacturers face during downstream purification and how addressing the traditional thinking surrounding chromatography resins, and buffers can be highly advantageous and immensely cost-effective. Take a listen to episode 2 below, and if you want to check out episode 1, click here!

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Materials Sourcing: Precautions and Improvements for Cell and Gene Therapies Dec 01, 2022

The success and applications of cell and gene therapies are seemingly limitless, and economic forecasts project a compound annual growth rate of almost 40% over the next eight years. This rapid expansion is a double edge sword for biomanufacturers of cell and gene therapy products. On the one hand, the tremendous growth is excellent for business. Yet, on the flip side, biomanufacturers are faced with solving the numerous challenges of scaling-up production workflows: from raw material sourcing to supply chain management to adopting new and innovative production modalities. Having a trusted global partner that can help organizations navigate the tumultuous bioprocessing waters of cell and gene therapy production is advantageous and often the key to continued success in the space.

In this GENcast, we sit down with the Executive Vice President of Biopharma Production at Avantor, Dr. Ger Brophy, to discuss some of the precautions and improvements for cell and gene therapies and how manufacturers can address many of the challenges they face. Take a listen!

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Mechanistic Modeling Improves Drug Discovery Workflows and Speeds Therapeutic Development Dec 01, 2022

This is the final episode in our three-part GENcast series, where we discuss the virtues of mechanistic modeling and how it can significantly impact critical decision-making points in the drug discovery process, especially as drug developers move closer toward the IND process. In our two previous podcasts, we were introduced to mechanistic modeling concepts and the basics of how they can be applied to drug discovery workflows. You can listen to the earlier podcasts with the following links: episode 1, episode 2. In this latest GENcast, I met up once again with Dr. John Burke, President, CEO, and Co-founder of Applied BioMath, to discuss the specific applications of mechanistic modeling, especially concerning the process of deciding the first human dose numbers, and how his company is helping biotech and pharma organizations reduce their late-stage drug attrition rates. Take a listen!

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Moving the Drug Pipeline Forward with Mechanistic Modeling Dec 01, 2022

This is part two in our three-part GENcast series, where we discuss various aspects of the drug discovery and development process and, in particular, how advanced computational techniques like mechanistic modeling can help advance the therapeutic drug pipeline for many developers. In our initial podcast, we were introduced to mechanistic modeling concepts and the basics of how they can be applied to drug discovery workflows. In this latest GENcast, I sat down once again with Dr. John Burke, President, CEO, and Co-founder of Applied BioMath, to take a deeper dive into the specific applications of mechanistic modeling and how his company is helping biotech and pharma organizations reduce their late-stage drug attrition rates. Take a listen!

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Reducing Drug Discovery and Development Risk with Mechanistic Modeling May 02, 2022

The drug discovery and development process can be an arduous endeavor. Manufacturers spend considerable resources and money chasing down potential candidate molecules to create a potential new therapeutic—often resulting in abandoning the candidate in the very later stages of development due to minor factors that might have been overlooked at the onset of the discovery process. Thankfully, there have always been those investigators who sought to merge the fields of mathematics and biology while taking advantage of advanced computing algorithms to help inform and de-risk drug discovery decisions and streamline the development pipeline. This mechanistic modeling approach is helping to transform drug R&D projects by giving pharma and biotech companies the vital information they need to make the critical decisions in a drug’s path toward clinical success.

In this GENcast, we sat down with an expert in mechanistic modeling to discuss the specific of this approach and how companies are employing the technology successfully. Jump into the discussion and take a listen!

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Meet the Editor-in-Chief of GEN Biotechnology: Hana El-Samad, PhD Dec 17, 2021

GEN Biotechnology is the new peer-reviewed journal launching in early 2022 by Mary Ann Liebert Inc. aiming to publish outstanding original research and perspectives across the biotech field.

In this Q&A, GEN Biotechnology Senior Editor, Fay Lin, PhD, interviews Editor-in-Chief, Hana El-Samad, PhD, about her scientific research, outreach, and vision for the journal.

Learn more about GEN Biotechnology:

Website: www.genbiotechjournal.com

Twitter: @GENBiotechJrnl

Send editorial inquiries to editor@genbiotechjournal.com

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Interrogating the Links between Genetics and Psychiatric Disorders with High Throughput Assays Dec 02, 2021

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Navigating the Regulatory Terrain during Cell & Gene Therapy Production Jun 09, 2021

Navigating the Regulatory Terrain during Cell & Gene Therapy Production by Genetic Engineering and Biotechnology News

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Solve Your Biotherapeutic Challenges with Help from Gene Therapy University May 05, 2021

Solve Your Biotherapeutic Challenges with Help from Gene Therapy University by Genetic Engineering and Biotechnology News

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Engineered Therapy: Ramping Up CAR-T Biomanufacturing Goals Jan 11, 2021

Engineered Therapy: Ramping Up CAR-T Biomanufacturing Goals by Genetic Engineering and Biotechnology News

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What is so different about CRISPR Founder breeding? Dec 16, 2020

Gretchen Kusek, PhD, Associate Director Scientific Services, and Bart Smits, PhD, Manager Genetic Sciences and Compliance, discuss the key considerations when breeding gene-edited animals using CRISPR, particularly in the context of mosaicism.

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Collaborating for Filtration Success, Virtually Dec 02, 2020

Collaborating for Filtration Success, Virtually by Genetic Engineering and Biotechnology News

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Back to the Lab – Embracing Change Nov 20, 2020

Back to the Lab – Embracing Change by Genetic Engineering and Biotechnology News

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Virtual Becomes Reality for Biopharma Vaccine Development Oct 29, 2020

Virtual Becomes Reality for Biopharma Vaccine Development by Genetic Engineering and Biotechnology News

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Digital Tools Push Single-Use Technology Challenges to the Side Sep 16, 2020

Digital Tools Push Single-Use Technology Challenges to the Side by Genetic Engineering and Biotechnology News

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The Quiet Voice of Immunotherapy That's Starting to Be Heard Aug 24, 2020

The Quiet Voice of Immunotherapy That's Starting to Be Heard by Genetic Engineering and Biotechnology News

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Virtual Collaborations Push Pharma Forward During Pandemic Jul 30, 2020

With regions of the world cycling through societal re-openings and shutdowns due to the ongoing coronavirus pandemic, pharma and life science companies are tasked with trying to find creative solutions that help keep production lines moving, as well as drive innovation forward. For instance, pharmaceutical manufacturers still need to meet critical project timelines so that patients receive the therapies they require. As such, many companies require varying levels of technical support to accomplish their goals—a scenario made much more difficult due to travel and in-person meeting restrictions. Thankfully, the resilient team at the M Lab™ Collaboration Centers from MilliporeSigma were able to work out virtual solutions to support their partner Vuab Pharma reach their manufacturing goals. Take a listen to this latest GENcast and see how the virtual world stepped up to help the pharma space.

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3D Cell Models Push Drug Discovery Screening into High Gear Jul 29, 2020

David Sorrell, PhD, from Horizon Discovery, speaks with GEN about the importance of cell models in the drug discovery process.

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GENcast: CRISPR Screens Speed Drug Discovery Efforts for Disease Intervention Jun 25, 2020

GENcast: CRISPR Screens Speed Drug Discovery Efforts for Disease Intervention by Genetic Engineering and Biotechnology News

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Impact of COVID-19 on the Life Sciences Industry May 26, 2020

Impact of COVID-19 on the Life Sciences Industry by Genetic Engineering and Biotechnology News

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Trends in Bioprocess 4.0 and their Impact on Biomanufacturing May 04, 2020

Trends in Bioprocess 4.0 and their Impact on Biomanufacturing by Genetic Engineering and Biotechnology News

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GENcast: Navigating Your Lab through a Digital Transformation Mar 19, 2020

GENcast: Navigating Your Lab through a Digital Transformation by Genetic Engineering and Biotechnology News

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Helping Biosimilars Emerge into Global Markets Takes a Practiced Hand Feb 25, 2020

Helping Biosimilars Emerge into Global Markets Takes a Practiced Hand by Genetic Engineering and Biotechnology News

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Find the Right Fit when Tackling Late Stage Bioprocessing Challenges Jan 08, 2020

Filtration, filtration, filtration! It’s one of the critical factors to instituting a successful biomanufacturing process and often the element that gives scientists and engineers the most difficulty. Late-stage bioprocesses often require large volume manufacturing to meet supply requirements, and these increased volumes create challenging filtration operations—disrupting facility fit. Because so much is at stake for companies to generate bioproducts in short timeframes, when faced with these types of bioproduction challenges, organizations will waste valuable time and resources on developing creative solutions, in addition to making undesirable capital purchases. In this GENcast, we explore different troubleshooting techniques that the M Lab™ Collaboration Center experts employed, together with Biogen, to solve their facility fit challenges.

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Antibody Drug Conjugates: Manufacturing Precision Guided Therapeutics Nov 18, 2019

While the idea of a magic bullet that treats all maladies is a concept grounded in antiquity, antibody drug conjugates (ADCs) get a lot closer than almost any other class of drugs. The coupling of broadly cytotoxic compounds to the precision targeting of monoclonal antibodies creates a therapeutic weapon of disease destruction. Yet, as with most biotherapeutic manufacturing processes, scaling-up these compounds efficiently is never straight forward. Still, with the global ADC market proliferating, scientists and engineers are looking for the best path forward to address their bioprocessing challenges.In this GENcast, we hear from a panel of ADC experts about how they have addressed some of the most challenging aspects of manufacturing these complex therapeutics and how they are reading the current ADC manufacturing terrain.

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GENcast: Welcoming a Digital Revolution in Life Science Oct 18, 2019

GENcast: Welcoming a Digital Revolution in Life Science by Genetic Engineering and Biotechnology News

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Vaccinating the World One Collaboration at a Time Oct 17, 2019

Positive global health outcomes are often contingent on more than just great science, as knowledge sharing is also a fundamental part of achieving public health goals. With drug resistance on the rise for many pathogens once thought well managed clinically, scientists are looking toward the development of new vaccines to help reduce morbidity and mortality for many global diseases. Collaboration between academia, industry, suppliers, and government organizations is crucial for the successful development of these vaccines, as these intellectual exchanges help accelerate production timelines, reduce costs, and increase chances of bringing an essential vaccine to market. The experts from the M Lab™ Collaboration Centers at MilliporeSigma are no strangers to knowledge sharing and have been involved in supporting a number of successful vaccine development projects. In this GENcast, we talk to a diverse group of public health scientists and discuss their vaccine development projects and how the M Lab Collaboration Centers were able to assist them toward positive outcomes.

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GENcast Explore, Learn, & Collaborate On Viral Safety In Biomanufacturing Sep 04, 2019

GENcast Explore, Learn, & Collaborate On Viral Safety In Biomanufacturing by Genetic Engineering and Biotechnology News

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GENcast: Explore, Learn, and Collaborate on Bioprocessing Challenges in China Aug 27, 2019

Great symphonic music starts with the fundamental elements common to all orchestral instruments, but what separates a good symphony from a great one is not just pure talent, but the ability of the musicians to work together to create something ethereal. In most respects, science is no different. The open exchange of ideas and collaborative spirit is how science moves forward to create something impactful for society. And like great instrumentalists, scientists practice their craft every time they step into the laboratory—but even the most talented amongst them requires assistance on occasion.The need for these collaborative scientific environments is most apparent in emerging biotechnology regions like China, where companies are quickly ramping up biomanufacturing processes to become competitive with more established biotech hubs. Scientists at the M Lab™ Collaboration Centers from MilliporeSigma are well versed in supporting scientists and engineers and assisting them with bioprocessing challenges that can make even the most harmonious scientific teams go out of tune. They M Lab Collaboration Centers’ team has the expertise to assist growing companies with manufacturing scale-up questions, provide chromatography support, and offer the latest expertise on single-use bioprocessing systems.We connected recently with a few members of the M Lab Collaboration Centers to discuss some of the recent, successful projects they collaborated on with clients in China. They discuss some of the challenges they faced on their project, how they set out to resolve those issues, and what the future holds for them and the Chinese biopharma market. Listen in to the conversation below.

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Empowering a Precision Health Movement with Kevin Hrusovsky Aug 26, 2019

Empowering a Precision Health Movement with Kevin Hrusovsky by Genetic Engineering and Biotechnology News

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GENcast Explore, Learn, & Collaborate As Next-Generation Bioprocessing Moves Toward Future Horizons Jul 18, 2019

GENcast Explore, Learn, & Collaborate As Next-Generation Bioprocessing Moves Toward Future Horizons by Genetic Engineering and Biotechnology News

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GENcast Interview with Quanterix CEO Kevin Hrusovsky Jul 15, 2019

GENcast Interview with Quanterix CEO Kevin Hrusovsky by Genetic Engineering and Biotechnology News

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Nanostring Podcast with David Rimm, MD, PhD Jul 03, 2019

Nanostring Podcast with David Rimm, MD, PhD by Genetic Engineering and Biotechnology News

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ATCC Podcast Final Jun 11, 2019

ATCC Podcast Final by Genetic Engineering and Biotechnology News

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GENcast: Explore, Learn, and Collaborate on Regulatory Challenges in Asia Mar 27, 2019

GENcast: Explore, Learn, and Collaborate on Regulatory Challenges in Asia by Genetic Engineering and Biotechnology News

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GENcast: Explore, Learn, and Collaborate on Cell & Gene Therapy Manufacturing Challenges Mar 06, 2019

GENcast: Explore, Learn, and Collaborate on Cell & Gene Therapy Manufacturing Challenges by Genetic Engineering and Biotechnology News

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GENcast: Explore, Learn, and Collaborate on Bioproduction Training in Asia-Pacific Feb 07, 2019

They say, “good talent is hard to find!” This is especially true for emerging high-growth markets where many in the workforce lack the advanced skills necessary to aid their bioproduction needs and expand their market profile. Leveraging the success of the M Lab™ Collaboration Centers, the MilliporeSigma team was able to foster key collaborations with government agencies to provide essential hands-on training programs in various Asia-Pacific countries such as Singapore and Taiwan. In this podcast, we will hear from the individuals that were integral to launching these vital initiatives.Chii-Wann Lin, PhD Vice President and General Director of Biomedical Technology and Device Research Laboratories, and Industrial Technology Research Institute (ITRI).Chin Bin Tan, Head of Technology Management, APAC, MilliporeSigma.This is part two in the five-part podcast series tackling diverse issues such as the need for speed to market in gene therapy, next-generation bioprocessing, and viral safety assurance in upstream and downstream. Make sure you check back regularly to hear the latest GENcast session.

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GENcast: Explore, Learn, and Collaborate on Next-Generation Bioprocessing Dec 13, 2018

GENcast: Explore, Learn, and Collaborate on Next-Generation BioprocessingAs biomolecules become increasingly complex and manufacturer pipelines more diversified, scientists are searching for new ways to overcome the challenges of rapidly changing bioprocessing platforms. In this podcast, we have gathered an array of industry experts to discuss their efforts with the M Lab™ Collaboration Centers around the globe to address some of the latest developments in Next-Generation Bioprocessing.This is the first in a five-part podcast series tackling diverse issues such as the need for speed to market in gene therapy, the demand for personnel training in emerging markets, and viral safety assurance in upstream and downstream. So, make sure you check back regularly to hear the latest GENcast session.Panelists: Torsten Bisschop, Karen Chan, Matteo Costioli, PhD, Mike Felo, and Emily Petersonhttps://www.genengnews.com/resources/podcasts/gencast/next-gen-bioprocessing-millipore/

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Illumina’s Acquisition of PacBio: Accelerating the Pace of Genomic Discovery Nov 06, 2018

GEN Sounds of Science November 5, 2018Illumina just purchased Pacific BioSciences (PacBio) for $1.2 billion. Shawn Baker formerly worked for Illumina as both a scientist and manager. He currently serves as the chief science officer for AllSeq and as a genomics startup advisor and consultant at SanDiegOmics.com. GEN asked Shawn about the significance of Illumina buying PacBio to the sequencing market and to obtain his take on what’s driving the Illumina deal?

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Streamlining the Peptide Synthesis Process Jun 05, 2018

GEN Sounds of Science June 1, 2018CEM Corporation Applies Advanced Microwave TechnologyCEM provides microwave instrumentation for researchers involved in analytical and synthetic chemistry. Major application areas include acid digestion for elemental analysis, compositional testing of food products, peptide synthesis, and chemical synthesis.GEN recently spoke to Michael J. Karney, CEM’s life science product manager. During a sponsored pocast, Mr. Karney described how CEM’s technologies are improving workflows for end users, specifically in the fields of drug design and development.

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Lentiviral Systems for Gene Delivery May 01, 2018

GEN Sounds of Science May 1, 2018GEN recently spoke to Minjun Liu, Ph.D., marketing director for OriGene, for a sponsored podcast. OriGene Technologies was founded as a research tool company focused on the creation of a large commercial collection of full-length human cDNAs in a standard expression vector. Company officials say the firm’s mission is to prepare comprehensive, genome-wide research tools and technology platforms to allow scientists to better study complete biological pathways. The goal is to enable more detailed insights into stem-cell research and into disease mechanisms, such as those that lead to cancer.

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Transforming the Bioresearch and Healthcare Industries Jan 26, 2018

GEN Sounds of Science January 26, 2018Technology and Data Usher in a New Age in MedicineHaving the right data and knowing how to use it will be the key to success in the healthcare market in the future.

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Inhibiting Cancer Metastasis Nov 29, 2017

GEN Sounds of Science November 29, 2017Canadian team identifies protein that when hindered decreases invasion rate of cancer cells.

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New Method Developed for Growing Tissue Engineered Corneas Oct 24, 2017

GEN Sounds of Science October 23, 2017Researchers discovered that corneal cells isolated from human donors and grown on a dome-shaped surface behaved differently than those on flat one. There are a number of advantages to using such curved substrates.

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Millipore Says It is Bullish on Continuous Bioprocessing Sep 26, 2017

GEN Sounds of Science September 15, 2017MilliporeSigma is using is expertise in biomanufacturing to take advantage of the growing interest in continuous or next generation bioprocessing. The company is investing in specific technologies in terms of dedicated teams, focused R&D efforts, and product-development projects.Website: http://www.emdmillipore.com/

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New Drug Delivery Materials May Help Patient Compliance with Meds Aug 01, 2017

Hydrogels May Last in Stomach for Lengthy Periods of TimeGEN Sounds of Science January 9, 2017Researchers at MIT and Brigham and Women's Hospital create triggerable tough hydrogels. Hydrogels may last in stomach for lengthy periods of time.

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Looking at the CAR-T Landscape As First Approval Nears Jul 19, 2017

GEN Sounds of Science July 18, 2017Brad Loncar, CEO of Loncar Investments, discusses the outlook for chimeric antigen receptor T cell (CAR-T) cancer therapies as Novartis nears FDA approval for the first such treatment, CTL019. Some other CAR-T therapies have also shown early, yet promising, clinical data.

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Is Calcium the Achilles Heel for Clostridium Infections? Jul 14, 2017

GEN Sounds of Science July 13, 2017]Findings from a new study published in PLOS Pathogens by investigators at the University of Michigan and the FDA underscores the importance of calcium in Clostridium difficile spore germination.Study Link: http://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1006443

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SARS and MERS Inhibited by Ebola Drug Jun 29, 2017

GEN Sounds of Science June 29, 2017A research team from Vanderbilt University, University of North Carolina, and Gilead Sciences has just released new findings in Science Translational Medicine describing how a new antiviral drug candidate inhibits a broad range of coronaviruses, including SARS and MERS.Link to artice: http://stm.sciencemag.org/content/9/396/eaal3653

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Bioengineers Use Quantum Dots to Help Develop New Therapies for MS Jun 19, 2017

GEN Sounds of Science June 19, 2017Team believes a rational therapeutic design approach will allow scientists to transform how the disease is tackled. Quantum dot technology also should be applicable to other autoimmune diseases as well.

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Soft Tissue Synthetic Retina Created May 31, 2017

GEN Sounds of Science May 25, 2017A synthetic, soft tissue retina developed by an Oxford University doctoral chemistry student could offer fresh hope for visually impaired people.

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FDA’s New Commissioner Hits the Ground Running May 19, 2017

GEN Sounds of Science May 19, 2017Sara Radcliffe, president and CEO of the California Life Sciences Association, discusses where Scott Gottlieb, M.D., is most likely to impact biopharma, and what the industry hopes he will accomplish as the FDA’s new commissioner.

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New Zika Test Shines LAMP in the Dark May 09, 2017

GEN Sounds of Science May 4, 2017A new test not only rapidly and inexpensively detects Zika virus in mosquitoes and human bodily fluids, but can also distinguish between African and Asian strains. Listen now for more details!http://stm.sciencemag.org/content/9/388/eaag0538

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Inflammation-Sensing Gut Bacteria Brought to You by Synthetic Biology Apr 17, 2017

GEN Sounds of Science April 14, 2017New research may eventually lead to orally ingestible bacteria for monitoring gut health and disease—with the ultimate goal being the development of a home inflammation test.

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Standing Up Against NIH Budget Cuts Apr 10, 2017

GEN Sounds of Science April 7, 2017Mary Woolley, President of Research!America, which advocates for medical and health research funding, talks about how her group and other advocates plan to fight back against President Donald Trump’s one-two punch to NIH funding. Researchers will be key to those efforts, she says.

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Is Maple Syrup the Answer to Antibiotic Resistance? Apr 03, 2017

GEN Sounds of Science April 3, 2017McGill University researchers may have found a natural way to cut down on antibiotic use without sacrificing health.

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Sensitive Genotypes and their Impact on Economic Success Mar 17, 2017

GEN Sounds of Science March 16, 2017A recent study suggest that children with sensitive genotypes who come from low-income homes will be less financially successful than their same sex sibling without those genotypes. But children with those same genotypes from a high-income home would actually fare better economically as young adults than their brother or sister.

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Cancer Immunotherapy: CAR T as 'Car Race' Mar 10, 2017

GEN Sounds of Science March 9, 2017Brad Loncar, CEO of Loncar Investments, weighs in on recent developments in the scramble to develop CAR T cancer immunotherapies. How significant a setback is Juno Therapeutics’ halting development of JCAR015? How could some second-tier companies yet come out on top in the “car race”?

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Turning Patients' Cells into Therapeutic Antibody Factories Mar 03, 2017

GEN Sounds of Science March 2, 2017A collaborative team of scientists demonstrates a novel method to deliver safer and more cost-effective therapeutic antibodies, utilizing mRNA.See Article: http://www.nature.com/articles/ncomms14630

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Cannibalism: A Biological and Evolutionary Perspective Feb 28, 2017

GEN Sounds of Science February 28, 2017Scientists have long written off cannibalism as a strange phenomenon with little biological significance. However, the true nature of cannibalism —the role it plays in evolution as well as human history — is even more intriguing (and more normal) than the misconceptions we’ve come to accept as fact.

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Seeking Young Scientists for Research in Space Feb 23, 2017

GEN Sounds of Science February 22, 2017Nicole M. Nichols, Ph.D., group leader for DNA amplification development at New England Biolabs, discusses the third national Genes in Space competition. The winner will have his or her experiment carried out aboard the International Space Station.More insights on space travel and DNA could emerge from experiments that seventh-through-12th graders will design. Deadline for submissions is April 21. Learn more at www.genesinspace.org.

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Sorting Out the CRISPR Patent Case Feb 17, 2017

GEN Sounds of Science February 16, 2017Bill Warren, partner with the law firm Eversheds Sutherland and chair of its biotechnology and life sciences team, discusses the ruling by a three-judge panel of the Patent Trial and Appeal Board siding with the Broad Institute of MIT and Harvard in the bitter legal battle over who invented CRISPR (clustered regularly interspaced short palindromic repeats) gene-editing technology.

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“Sexual Attraction” Neurons in the Brain Discovered Feb 03, 2017

GEN Sounds of Science February 2, 2017Finding in female mice may also be relevant to certain human psychiatric disorders.

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Best Practices for Closing the Gender Gap Feb 01, 2017

GEN Sounds of Science January 30, 2017Jodie Morrison, CEO and President of Tokai Pharmaceuticals, is one of nearly 200 biopharma leaders who recently signed an open letter endorsing a Top Ten of best practices for advancing gender diversity, from the boardroom to the C-suite to the lab.

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When the Pressure is High the Dementia is Low Jan 18, 2017

GEN Sounds of Science January 17, 2017Findings from a new study suggest that the onset of high blood pressure later in life is associated with lower dementia risk after age 90. Listen now for more details!Link to the study: http://www.alzheimersanddementia.com/article/S1552-5260(16)32962-4/fulltext

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Taking on the Multi-Drug-Resistant Bacteria Challenge Jan 11, 2017

GEN Sounds of Science January 10, 2017Entasis Therapeutics is working on novel therapies for serious drug-resistant bacterial infections, a global health crisis affecting the lives of millions of patients.

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What Trump Will Mean for Biomedical Research Jan 10, 2017

GEN Sounds of Science January 9, 2017Benjamin Corb, public affairs director for the American Society for Biochemistry and Molecular Biology (ASBMB), discusses what the biomedical research community can expect from the incoming administration of Donald J. Trump

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