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Without long chain omega-3 fatty acids, the development of the brain and nervous system would be impossible. This begs the question: what effects arise from long chain omega-3 fatty acid deficiency? Dr. Alex Richardson joins the show to discuss the following:
Dr. Alex Richardson is a research associate in the Department of Physiology, Anatomy, and Genetics at the University of Oxford, and founder of Food and Behavior (FAB) Research. Her interest in researching the role of nutrition in physical and mental health was triggered during her postdoctoral studies when she discovered how impactful long chain omega-3 fatty acids are on vision. Since then, she's been investigating how this essential nutrient may be related to conditions like ADHD, dyslexia, and disorders that fall on the autism spectrum.
Dr. Richardson published her first study about two decades ago, which demonstrated that omega-3 fatty acids could lower impulsivity, inattention, and hyperactivity in children with above average levels of these. Through a second study, she showed that omega-3 fatty significantly improved reading, spelling, and symptoms of ADHD in children.
Dr. Richardson already has protocols set for two more studies: one that will look at the effects of omega-3 on sleep, and how sleep may be associated with ADHD and autism, and a second that will look at the relationship between omega-3 and sleep health, and common mental health conditions like stress and depression.
Tune in for a compelling show that's full of eye-opening and powerful information. Learn more by visiting https://www.fabresearch.org/viewItem.php.
Richard J. Schwab, MD, DABSM, Head of Sleep Medicine, University of Pennsylvania, and the Co-Medical Director, Penn Sleep Center, discusses the pathogenesis of obstructive sleep apnea, and obstructive sleep apnea treatment. Podcast Points:
Dr. Schwab provides some background on his work and the various sleep problems that exist. He talks about sleep apnea, and why there is so much left to understand. Why does it happen when we sleep? He discusses soft tissue structures and lateral walls and other factors that can lead to airway paths collapsing. Dr. Schwab's extensive research seeks to target the pathogenesis of obstructive sleep apnea by using advanced upper airway imaging techniques. His studies help further explain the motion of various key structures of the upper airway and the role they play in airway closure. Dr. Schwab talks about the biomechanics of apneic events. He provides information on how they utilize magnetic resonance imaging and electronic beam computed tomography during sleep, as well as wakefulness, to study patients. Dr. Schwab talks about abnormal craniofacial structures as well as soft tissue, and how they can potentially impact sleep apnea occurrences. He discusses mouth breathing, studies they conducted on tongue fat, and how it all could impact breathing issues. As he states, if you naturally have a narrow airway, as movement occurs when you sleep, apnea could be initiated. He provides an in-depth discussion of how tissues move, and studies they have done on wakefulness. But he states there are more studies on sleep and breathing that they plan to do in the near future. Dr. Schwab, through his exhaustive research annually, collaborates regularly with members of the Departments of Radiology and Biomechanical and Computer Engineering. And together, the scientific researcher/developers have designed an extremely advanced, computer graphics-based analysis software that can assist with modeling, in three dimensions, of the biomechanical interrelationships that exist between soft tissue structures and the upper airway.
Dr. Walter studies the many functions of RNA, which combines into the most copious enzyme on our planet. RNA research is catching up with the rest of our genetic findings after DNA dominated the field for so long.
Dr. Walter plows into this knowledge by discussing
Dr. Nils Walter is the Francis S. Collins Collegiate Professor of chemistry, biophysics, and biological chemistry at the University of Michigan. He's also the founding codirector of the Center for RNA Biomedicine. The center researches foundational biological RNA discoveries and translates them for use towards future medicines.
Dr. Walter has been researching at the University of Michigan for 20 years; for the most part, his work has been focused on functional RNA types. In this conversation he offers a non-coding RNA review and recounts numerous discoveries, such as the structure and function connection and why it's important that RNA has a more transient nature than DNA.
He expands on this review by reminding listeners that when the human genome was sequenced in 2003, researchers discovered that just 1.5% of the genome codes for proteins while the rest is transcribed into RNA. These RNAs form multiple structures that become functional RNA types.
As he continues with his non-coding RNA review, he explains that RNA folds into intricate 3D architectures, which enables them to take on complex functions such as the formation of ribosomes. Dr. Nils describes additional jobs of the RNA molecule and articulates how these discoveries will lend themselves to future medicines.
For more, see his lab page at https://sites.lsa.umich.edu/walter-lab/ as well as the Center for RNA Biomedicine page at https://rna.umich.edu/.
In this podcast, Larry Simpson, PhD, Distinguished Professor Emeritus, Department of Microbiology, Immunology and Molecular Genetics, UCLA, provides an overview of his long career in scientific research.
Podcast Points:
Dr. Simpson has long been interested in the molecular biology of the mitochondrial genome of trypanosomes. He was a Howard Hughes Medical Institute Investigator, and throughout his extensive and celebrated career, Dr. Simpson was elected as a Foreign Member of the Brazilian Academy of Science, as well as a distinguished Fellow of the American Academy of Microbiology, and as a Member of the American Academy of Arts and Sciences.
Dr. Simpson provides some information about his background, past work, and current research. He talks about his career studying the molecular biology of the mitochondrial genome of trypanosomes, and why this area of study interested him so intently. Continuing, Dr. Simpson discusses the types of molecules he studied in past research.
Throughout the years of research, Dr. Simpson spent a fair amount of time investigating a novel type of RNA modification phenomenon known as 'RNA editing,' which occurs in the single mitochondrion. Dr. Simpson goes on to discuss DNA molecules, modification, translation, gene sequences, bacteria and function, and 'guide RNAs.'
He provides an overview of enzymes within the mitochondrion, discussing types of gene editing. And he goes into an in-depth discussion of how mRNA transcripts of the mitochondrial maxicircle DNA molecules are modified, after transcription, by the insertion, and deletion, of uridine residues at exact sites within coding regions to form a translatable sequence.
A list of web sites where people can get information on the parasites and the diseases:
Bio:
A Los Angeles native, Babak holds a clinical doctorate in clinical psychology from the California School of Professional Psychology, where he also obtained a master's in organizational behavior. He is the originator of the moderative psychotherapy. Currently living in Portland, Oregon with his wife and children, he is in private practice at Integrative NW as a clinical and health psychologist. Babak is also a fiction author and, as Secret Arcade, a music artist. Babak's writing debuted in North American Review ("Fighting Fish"), and he was a finalist for a Glimmer Train award. His story "Glow," published in Palo Alto Review, was deemed "flawless" and "brilliant" by Shenandoah literary review. His book, a dystopian psychological novel, A-Void, examines accelerating (exponential) change and information overload, and was selected as a Top Ten Book of 2018. Secret Arcade's debut electronic rock album, Quarter Century, skyrocketed on college radio. A popular docu-series on A&E/Lifetime recently offered him a role, but he turned it down to focus on his theory, his writing, his music, and his family. In this podcast, Babak Govan, PhD, MAOB, psychologist at Integrative NW, provides an overview of insomnia treatment, psychopathology, and more. Podcast Points:
Dr. Govan is actively engaged in helping people manage their anxiety and depression, ADHD, self-defeating behaviors, and substance abuse. Dr. Govan talks about his background and discusses health psychology, the interface of medical and psychological issues. Going deeper, Dr. Govan explains how his practice subspecializes in treating insomnia. Dr. Govan explains just how common depression is today in America, and he discusses the various sociogenic factors that may be exacerbating the rise in depression cases nationally. Dr. Govan discusses tools to manage psychological issues, such as cognitive behavioral therapy, but he stresses that cognitive behavioral therapy, CBT, is only one possible avenue for treatment. The PhD elaborates on the importance of limiting our negative influencers, such as the preponderance of negative news that is seemingly always breaking. He discusses his thoughts on the relative impact of modern technology that delivers news 24/7, and ways we can limit our exposure to negative influences. Continuing, the doctor discusses the concept of loneliness, and how technology may be severely disconnecting us. Dr. Govan talks about the kinds of clients they work with. He discusses the problem of insomnia, which can be a psychodynamic, deeper issue. He discusses abrupt insomnia versus cases in which people have had chronic sleep problems for a long period, and how the latter understand that it could be a long term issue for them to solve over time. Dr. Govan reiterates the importance of taking control of the environments in which we exist. He talks about time management, as well as journalistic errors, and how so often in our modern society, things fall through the cracks. Wrapping up, Dr. Govan provides information on the specific types of cases they deal with at Integrative NW, and how they seek to help people manage their many and varied issues.
In this podcast, Dr. Ty Carzoli, chiropractor at Denver Upper Cervical Chiropractic, discusses his facility and their work, providing information on chiropractic orthospinology, treatment, and care.
Podcast Points:
Denver Upper Cervical Chiropractic provides chiropractic care to people who suffer from pain and discomfort. Dr. Carzoli earned a doctorate of chiropractic and he holds a master's degree in sports health science.
Dr. Carzoli discusses neck and back problems, explaining the many issues his team treats at their facility, such as migraines and headaches, post-concussion syndrome, neck and back pain, seizures, and more. Dr. Carzoli explains how they exam new potential clients, starting with a complete and thorough digital x-ray analysis to fully assess the current structure, position, and motion of their spine. Testing motor skills and grip strength, Dr. Carzoli makes an assessment and decides if the incoming potential client would benefit from treatment.
Further, Dr. Carzoli talks about adjustments, and discusses how the body keeps us aligned, and why alignment issues may happen. He talks in detail about the unnatural forces we can experience at times, from high-impact collisions to excessive sitting, etc. These events, activities, or non-activities, can definitely cause damage to our bodies, and it is Dr. Carzoli's mission to assist everyone with their pain and discomfort.
In this podcast, Marni Amsellem, PhD, psychologist, talks about her work treating clients with cognitive behavioral therapy tools and techniques.
Podcast Points:
Dr. Amsellem works with many clients, helping them to develop tools to manage their anxiety, depression, health-related challenges and life changes. Dr. Amsellem talks about her areas of focus in cognitive behavioral therapy (CBT). She discusses insomnia, and explains how anxiety is sometimes the reason for poor sleep. CBT, she states, can help with underlying anxiety. Continuing, Dr. Amsellem discusses the triggers that can bring on anxiety in some people. There are multiple factors that can impact us negatively, and Dr. Amsellem discusses the many statements and thoughts that we communicate to ourselves, sometimes far below our conscious level even.
Dr. Amsellem provides an overview of various themes she hears from her clients regularly, such as concerns over failure, concerns over rejection, to feelings of worthlessness, and others. She breaks down some of the techniques she utilizes and explains how cognitive behavioral therapy can assist with those negative thoughts we sometimes have by helping us reframe them and overcome them. She talks about the importance of increasing our awareness of thoughts and triggers, and the patterns we gravitate toward. Wrapping up, Dr. Amsellem explains CBT in detail, and how it can be applied to real world situations and problems and help us create changes in our lives, for the better.
In this podcast, Niles Eldredge, evolutionary biologist and renowned paleontologist, discusses parallel causation in oncogenic and anthropogenic degradation and extinction, his thoughts on biological theory, and other topics.
Dr. Eldredge holds a PhD from Columbia University. He is the Curator Emeritus, Division of Paleontology, American Museum of Natural History.
Podcast Points:
Dr. Eldredge discusses his long background, and his noted career in the fields of biology and paleontology. Dr. Eldredge has contributed significant work in the study of mid-Paleozoic phacopid trilobites, and along with Stephen Jay Gould of Harvard, formulated an interesting theory that challenged Darwin's very premise that evolution occurs gradually. The theory they put on the table was known as Punctuated Equilibria, and it states that evolution occurs in dramatic spurts mixed in with extended periods of stasis.
Dr. Eldredge says there isn't much evolution really unless, and until, the 'clock' is turned over, such as what occurs when an extinction event happens. Evolution, in fact, is a rebound from an extinction event. When all is working properly, he states, things tend to stay the same. Dr. Eldredge provides information on climate change and the recipe for stability. He discusses some of the grave environmental dangers, discussing disruption and degradation, and the terrible damage being done to various species globally. He discusses how we have changed the environment considerably, and how more people globally will ultimately lead to more damage. Dr. Eldredge talks about urban environments and how they relate to the natural world, and the real possibility that we are on a track toward extinction.
This is a follow-up interview with Natura-brand founder and Mederi Foundation leader Donnie Yance. He offers a closer glimpse into the spiritual side of his journey. When you listen, you will her Donnie explain
Donnie Yance is the founder, president, lead clinician, and chairman of the Mederi Foundation. The foundation works with cancer patients in conjunction with oncologists, but also teaches quality of life healthcare and provides tips to live longer. Earlier in life, Donnie spent time at a Franciscan monastery and other spiritual centers. This time informs his current healing practice.
Still a Franciscan monk of the third order, he has extensive knowledge of numerous religious practices and explains some of the more meaningful elements. He recounts details like Eastern orthodox street greetings during the Easter season to how the Beatitudes differs from the Ten Commandments.
Finally, he describes his approach at the Mederi Foundation, how he delivers a handout to clients that explains his spiritual approach and what it means to heal the whole person.
For more, such as tips to live longer, see his website and a blog at https://www.donnieyance.com/ and the Mederi Foundation site at https://medericenter.org/
Allergic airway disease treatment may get better results from the use of antifungals. Dr. Li explains how this treatment seeks to eradicate fungi that may be accountable for some allergic symptoms.
He describes
Dr. Evan Li, faculty member at Baylor College of Medicine in Texas specializing in allergy and immunology diseases, treats patients in their clinic who have severe asthma symptoms. He discusses the nature of these fungi—how easy it is to take them in yet only certain patients have these stronger reactions.
For example, people are exposed to these fungi just by walking outside yet all don't have extreme reactions and infections. For some, however, these fungi can produce infections that reveal themselves as allergy and immunology diseases. While antihistamines are the standard issue for allergic airway disease treatment, they don't address the root cause of the fungal infection.
Dr. Li explains further that they only use this type of treatment for more severe cases, or what's termed severe persistent asthma. Because these patients come to the clinic with symptoms that are barely relived by standard treatment, the risks associated with antifungal treatment are outdone by the benefits.
For more such as a listing of papers he's authored, search for his name in pubmed and see his page at the Baylor College of Medicine: https://www.bcm.edu/people/view/evan-li-m-d-b-s/b177c08a-ffed-11e2-be68-080027880ca6
Email him with questions as well at eli@bcm@edu. Finally, his lab accepts sputum samples in a clean cup or zip lock bag, frozen and delivered to:
The Baylor College of Medicine Clinic8th Foor, Suite 8A7200 Cambridge St.Houston, TX 77030
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