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    Chemistry

    Distillations | Science History Institute

    Distillations is the Science History Institute’s critically acclaimed flagship podcast. We take deep dives into stories that range from the serious to the eccentric, all to help listeners better understand the surprising science that is all around us. Hear about everything from the crisis in Alzheimer’s research to New England’s 19th-century vampire panic in compelling, sometimes-funny, documentary-style audio stories.

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    Copyright: © Creative Commons Attribution-ShareAlike

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    Latest Episodes:
    Disappearing Spoon: The Harvard Medical School Janitor Who Solved a Murder Nov 16, 2021
    Show notes

    On this episode of The Disappearing Spoon, Sam Kean talks about a murder mystery that rocked Boston in 1849. Harvard University alum and physician George Parkman had gone missing. The last place he was seen alive was at the Harvard medical building, which had plenty of bodies, but police couldn't find Parkman's there. That is until a janitor intervened and implicated a medical school professor. The ensuing murder trial was a media circus equivalent to the O. J. Simpson trial. And just like that trial, it also familiarized the layperson with forensic and anatomical sciences.

    Credits

    Host: Sam Kean Senior Producer: Mariel Carr Producer: Rigoberto Hernandez Audio Engineer: Jonathan Pfeffer

    Photo: Wellcome Collection


    Disappearing Spoon: Burn After Watching Nov 09, 2021
    Show notes

    In this episode of The Disappearing Spoon, Sam Kean breaks down the history of nitrocellulose. This thick, transparent liquid was the world's first plastic and could be shaped into anything, including billiard balls and photography film. With nitrocellulose film, you could run reels of pictures together quickly, which gave birth to the first movies.

    The only fatal flaw with this plastic is that it's also extremely combustible—so much so that it can burn underwater once it gets going. This led to notable tragedies in movie theaters, as well as in hospitals that used nitrocellulose X-rays such as the Cleveland Clinic Hospital, where 122 people died in a fire in 1929.

    Credits

    Host: Sam Kean Senior Producer: Mariel Carr Producer: Rigoberto Hernandez Audio Engineer: Jonathan Pfeffer


    History's First Car Crash Victim Nov 02, 2021
    Show notes

    In this episode of The Disappearing Spoon, Sam Kean talks about Mary Ward, a budding naturalist and astronomer from Ireland. She spent a lot of time observing plants and animals through a microscope and published a book of detailed sketches that dazzled readers and colleagues in the 1800s. However, her career was cut short by a strange curiosity of that time period: the automobile. They weren't the same cars that are around today, but her death was the first car death recorded in history, and it foreshadowed the carnage the automobile continues to leave behind.

    Credits

    Host: Sam Kean Senior Producer: Mariel Carr Producer: Rigoberto Hernandez Audio Engineer: Jonathan Pfeffer


    Real Life Zombies Oct 26, 2021
    Show notes

    In this episode of The Disappearing Spoon, Sam Kean talks about memory fugues, a psychological disorder that wipes out biographical information from people's brains. It is estimated that roughly 1 in 100,000 people seeking help for mental disorders have them. This disorder happens worldwide and it usually afflicts people in their 20s. Scientists have only recently started to piece together what is going on in the brains of those impaired by it.

    Credits

    Host: Sam Kean Senior Producer: Mariel Carr Producer: Rigoberto Hernandez Audio Engineer: Jonathan Pfeffer


    How Climate Change Will Remake the Human Body Oct 19, 2021
    Show notes

    On this episode of The Disappearing Spoon, Sam Kean delves deep into the science behind the evolution of animal and human bodies. Like animals, human bodies have also evolved to adhere to the demands of ever-changing climates. This raises a question: how will human bodies respond to climate change?

    Credits

    Host: Sam Kean Senior Producer: Mariel Carr Producer: Rigoberto Hernandez Audio Engineer: Jonathan Pfeffer


    The 'Mary Poppins' Cancer Oct 12, 2021
    Show notes

    In this episode of Disappearing Spoon, Sam Kean discusses the horrors of a particular genetic disease that was, literally, sweeping through London in the 1700s. In 1666, the Great Fire of London consumed about 13,000 homes and caused the modern equivalent about $1.3 billion in damage. After the Great Fire, London officials made chimneys mandatory in all homes and buildings. All these new chimneys meant there was a big demand for sweepers. Who did they employ to clean these narrow, soot-filled chimneys you ask? Very young boys.

    Credits

    Host: Sam Kean Senior Producer: Mariel Carr Producer: Rigoberto Hernandez Audio Engineer: Jonathan Pfeffer


    Disappearing Spoon: Kangaroo (and Pig and Monkey and Dog and Donkey) Courts Oct 05, 2021
    Show notes

    Animal trials have always been part of society, but we are not talking about the ones with lab mice. In medieval times dozens of animals were tried in human courts for committing human crimes. It sounds silly, but the practice raises an uncomfortable question that we are still grappling with today: if we hold animals accountable in court, doesn't that mean that they deserve some sort of legal protection? We kill them for food and skin them for leather after all. What about medical and product trials that sacrifice thousands of animals despite the fact that they have had diminishing returns throughout the years?

    Credits

    Host: Sam Kean Senior Producer: Mariel Carr Producer: Rigoberto Hernandez Audio Engineer: Jonathan Pfeffer


    Murder, Fraud, Sabotage, Piracy, and Other Dastardly Deeds Perpetrated in the Name of Science Sep 28, 2021
    Show notes

    The Disappearing Spoon, a podcast collaboration between the Science History Institute and New York Times best-selling author Sam Kean, returns for its second season on October 5, 2021.

    To celebrate, our producer, Rigoberto Hernandez, sat down with Kean to talk about his new book The Icepick Surgeon: Murder, Fraud, Sabotage Piracy, and Other Dastardly Deeds Perpetrated in the Name of Science. This interview is a great companion piece for The Disappearing Spoon series since some of the stories in the book relate directly to some of the stories in the upcoming season.

    In this interview Kean talks about some of the case studies in his book, including how Thomas Edison shifted his ethics on the death penalty because of a grudge, how a part-time chemist from Philadelphia became an unlikely spy, and how an American doctor purposefully infected people in Guatemala with venereal diseases—all in the name of science.

    Hosts: Alexis Pedrick and Elisabeth Berry Drago Senior Producer: Mariel Carr Producer: Rigoberto Hernandez Audio Engineer: Jonathan Pfeffer


    What Causes Alzheimer's? Sep 21, 2021
    Show notes

    The human brain is mysterious and complicated. So much so, one might be tempted to argue that it only makes sense that we still don't have a cure for Alzheimer's disease, despite decades of research. But this isn't the whole story. We've partnered with Vox's Unexplainable science podcast to talk about how Alzheimer's researchers have been stubbornly pursuing a single theory for decades. The Amyloid Hypothesis is the reigning champ amongst pharmaceutical companies and scientific scholars and it has pushed all other theories to the wayside. Over the years scientists have developed many drugs based on the Amyloid Hypothesis but the the clinical trials keep failing. Now some researchers are starting to wonder if the reason we still don't have a cure is that we've put all of our scientific eggs in one faulty basket. You can hear more about the Alzheimer's disease on the previous Distillations Podcast episodes: The Alzheimer's Copernicus Problem Parts 1 and 2.

    Credits:

    Distillations:

    Hosts: Alexis Pedrick and Elisabeth Berry Drago Senior Producer: Mariel Carr Producer: Rigoberto Hernandez Audio Engineer: Jonathan Pfeffer

    Unexplainable:

    This episode was produced by Rigo Hernandez, Alexis Pedrick, Dylan Scott, and Byrd Pinkerton. It was edited by Noam Hassenfeld and Brian Resnick, with help from Meradith Hoddinott and Mandy Nguyen, who also did the fact checking. Noam Hassenfeld wrote the music, Cristian Ayala did the mixing and sound design.

    Image courtesy of Vox Media Group.


    What the All Souls Trilogy Teaches Us about Alchemy, Family, and Knowledge Hierarchy Aug 24, 2021
    Show notes

    Ever since the book A Discovery of Witches debuted in 2011, the All Souls franchise has taken on a life of its own with devoted fans all over the world. The TV show and annual All Souls Con—which the Science History Institute occasionally hosts—is based on the trilogy of books about witches, vampires, and demons by author Deborah Harkness.

    Distillations sat down with Jen Daine and Cait Parnell, the hosts of the All Souls podcast, Chamomile and Clove; art historian Stephenie McGucken; and medievalist actor, journalist, and author Sarah Durn to talk about the series' alchemical roots, the material culture in the TV show, and how the book's found-family theme mirrors the fandom.

    Credits

    Hosts: Alexis Pedrick and Elisabeth Berry Drago Senior Producer: Mariel Carr Producer: Rigoberto Hernandez Audio Engineer: Jonathan Pfeffer


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