Curiosity Weekly - Discovery

Latest Episodes:

Nano Cancer Fight, Memory Structure, Coffee Buzz Days Aug 24, 2022

Show notes

You’re going to learn about how our body’s pH is helping us fight cancer, how memories aren’t stored where we thought they were, and how drinking coffee could have you spending a lot more at the store.

Ph power.

“pH-Responsive Nanoparticles for Cancer Immunotherapy: A Brief Review” by Yunfeng Yan and Hangwei Ding
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7466692/
Polycarbonate-based ultra-pH sensitive nanoparticles improve therapeutic window by Xu Wang, et al.
- https://www.nature.com/articles/s41467-020-19651-7
Lighting up cancer cells with pH-activated nanoparticles by Angus Chen
- https://www.statnews.com/2022/04/10/lighting-up-cancer-cells-with-ph-activated-nanoparticles/
Cancer Statistics by National Cancer Institute
- https://www.cancer.gov/about-cancer/understanding/statistics

Memory box.

“A Single Memory is Stored Across Many Connected Brain Regions” by The Picower Institute
- https://picower.mit.edu/news/single-memory-stored-across-many-connected-brain-regions
“Innovations and Inventions: SHIELD” by The Picower Institute
- https://picower.mit.edu/innovations-inventions/shield
“Protection Of Tissue Physicochemical Properties Using Polyfunctional Crosslinkers” by Young-Gyun Park, et al.
- https://www.nature.com/articles/nbt.4281?WT.feed_name=subjects_microscopy
“Memory” by Queensland Brain Institute
- https://qbi.uq.edu.au/brain-basics/memory

Don’t drink before you shop.

“Caffeine Consumption Leads to Impulsivity during Shopping, New Study Shows” by Natali Anderson
- http://www.sci-news.com/othersciences/psychology/caffeine-shopping-impulsivity-10913.html
“EXPRESS: Caffeine's Effects on Consumer Spending” by Dipayan Biswas, Patrick Hartmann, Martin Eisend, Courtney Szocs, Bruna Jochims, Vanessa Apaolaza, Erik Hermann, Cristina M. López, and Adilson Borges.
- https://journals.sagepub.com/doi/abs/10.1177/00222429221109247

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Find episode transcripts here: https://curiosity-daily-4e53644e.simplecast.com/episodes/nano-cancer-fight-memory-structure-coffee-buzz-days

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Making Dragon Fire, Dating Ghosts, Blazing Fast Covid Tests Aug 19, 2022

Show notes

Tune in to learn about how fire-breathing creatures are possible, what makes a bad breaker-upper, and new blazing fast, cheap, and accurate COVID tests.

Dragons could be real.

“House Of The Dragon: Yes, fire-breathing animals could really exist” by Stephen Kelly
- https://www.sciencefocus.com/nature/house-of-dragon-fire-breathing/
“What Does Science Say About Flying and Fire Breathing Dragons?” by Anne Marie Helmenstine
- https://www.thoughtco.com/the-science-behind-flying-and-fire-breathing-dragons-4163130#:~:text=After%20all%2C%20a%20flying%2C%20fire,found%20in%20the%20wild%20today

Break up with someone the right way.

“Study finds “ghosting” short-term partners is associated with psychopathy and Machiavellianism” by Emily Manis
- https://www.psypost.org/2022/04/study-finds-ghosting-short-term-partners-is-associated-with-psychopathy-and-machiavellianism-62982
“Dark Triad” by Psychology Today
- https://www.psychologytoday.com/us/basics/dark-triad

Speed meets accuracy with covid tests.

UT Dallas Researchers Develop Accurate Rapid Test for Viruses by University of Texas at Dallas
- https://www.eurekalert.org/news-releases/950413
COVID-19 and PCR Testing by Cleveland Clinic
- https://my.clevelandclinic.org/health/diagnostics/21462-covid-19-and-pcr-testing
Digital Plasmonic Nanobubble Detection for Rapid and Ultrasensitive Virus Diagnostics by Yaning Lui, et al.
- https://www.nature.com/articles/s41467-022-29025-w

Find episode transcripts here: https://curiosity-daily-4e53644e.simplecast.com/episodes/making-dragon-fire-dating-ghosts-blazing-fast-covid-tests

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Rice TV Screen, Satellite Warfare, Unraveled DNA Aug 18, 2022

Show notes

Do you want to know about a new environmentally friendly way to make TV Screens, what future space warfare might look like, and how we have finally completely unraveled the human genome?

Rice is more than food. It’s TV.

World’s First LED Lights Developed from Rice Husks by Hiroshima University
- https://www.hiroshima-u.ac.jp/en/news/70366
Orange–Red Si Quantum Dot LEDs from Recycled Rice Husks by Shiho Terada, et al.
- https://pubs.acs.org/doi/10.1021/acssuschemeng.1c04985#
What is Quantum Dot Display Technology? by Dave Haynes
- https://insights.samsung.com/2021/12/29/what-is-quantum-dot-display-technology/
Exploring the Environmental Impact of Quantum Dots by Rachel Berkowitz
- https://physicstoday.scitation.org/do/10.1063/pt.5.7339/full/

Space weapons.

Analysts Warn Anti-Satellite Weapons Have Evolved Beyond Missiles by Wired
- https://www.wired.com/story/analysts-warn-anti-satellite-weapons-have-evolved-beyond-missiles/
Russia Conducts Destructive Anti-Satellite Missile Test by Anthony Blinken
- https://www.state.gov/russia-conducts-destructive-anti-satellite-missile-test/
UK Presses UN on Treaty Over Space Weapons by Amanda Miller
- https://www.airforcemag.com/uk-un-treaty-to-ban-anti-satellite-tests/
Satellite Debris Forces Space Station Crew to Take Shelter; U.S. Blames "Reckless" Russian Missile Test by William Harwood
- https://www.cbsnews.com/news/satellite-debris-space-station-crew-take-shelter/
Strategic Defense Initiative (SDI) by Atomic Heritage Foundation
- https://www.atomicheritage.org/history/strategic-defense-initiative-sdi

100% Genome.

Complete Human Genome Sequenced for First Time In Major Breakthrough by Becky Ferreira
- https://www.vice.com/en/article/y3v4y7/complete-human-genome-sequenced-for-first-time-in-major-breakthrough
The Complete Sequence of a Human Genome by Sergey Nurk, et al.
- https://www.science.org/doi/10.1126/science.abj6987
What is the Human Genome Project by The National Human Genome Research Institute
- https://www.genome.gov/human-genome-project/What
A Brief Guide to Genomics by The National Human Genome Research Institute
- https://www.genome.gov/about-genomics/fact-sheets/A-Brief-Guide-to-Genomics

Find episode transcripts here: https://curiosity-daily-4e53644e.simplecast.com/episodes/rice-tv-screen-satellite-warfare-unraveled-dna

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AI vs. Parkinson’s, Dark Sun Power, Death Proof Jellyfish Aug 17, 2022

Show notes

Ever wonder about the artificial intelligence helping us find and fight Parkinson’s disease? What about the new methods for collecting energy from solar panels at night or how the tiny immortal jellyfish may help us massively extend our lifespans. Tune in to learn more!

Robots that help.

Artificial Intelligence and Robotics Uncover Hidden Signatures of Parkinson’s Disease by New York Stem Cell Foundation
- https://neurosciencenews.com/parkinsons-ai-robotics-20259/
Integrating Deep Learning and Unbiased Automated High-Content Screening to Identify Complex Disease Signatures in Human Fibroblasts by Lauren Schiff, et al.
- https://www.nature.com/articles/s41467-022-28423-4#Sec10
What is Parkinsons by Ahmad Elkouzi
- https://www.parkinson.org/understanding-parkinsons/what-is-parkinsons
Our Agenda by The Michael J. Fox Foundation
- https://www.michaeljfox.org/our-agenda

Solar but at night.

Stanford Engineers Invent a Solar Panel That Generates Electricity at Night by Grant Currin
- https://interestingengineering.com/stanford-solar-panel-night
Nighttime Electric Power Generation at a Density of 50 mW/m2 Via Radiative Cooling of a Photovoltaic Cell by Sid Assawaworrarit, et al.
- https://aip.scitation.org/doi/10.1063/5.0085205
How Do Solar Panels Work by Michael Dhar and Ailsa Harvey
- https://www.livescience.com/41995-how-do-solar-panels-work.html
Solar Panels That Can Generate Electricity at Night Have Been Developed at Stanford by Rina Torchinsky
- https://www.npr.org/2022/04/07/1091320428/solar-panels-that-can-generate-electricity-at-night-have-been-developed-at-stanf

Jellyfish: the secret to life.

The Secrets of the Immortal Jellyfish, Earth's Longest-Living Animal by Thomas Ling
- https://www.sciencefocus.com/nature/immortal-jellyfish/
Turritopsis dohrnii: The Life Cycle of the Immortal Jellyfish by The Real Immortal Jellyfish
- https://therealimmortaljellyfish.com/
Cellular Reprogramming and Immortality: Expression Profiling Reveals Putative Genes Involved in Turritopsis dohrnii’s Life Cycle Reversal by Yui Matsumoto and Maria Pia Miglietta
- https://doi.org/10.1093/gbe/evab136

Find episode transcripts here: https://curiosity-daily-4e53644e.simplecast.com/episodes/ai-vs-parkinsons-dark-sun-power-death-proof-jellyfish

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Poop of Youth, Robot Roaches, Chatty Fungus Aug 12, 2022

Show notes

Learn about how we might be flushing the secret to anti-aging down the toilet, how cyborg cockroaches could save your life one day and how mushrooms may be talking to each other!

The connection between poop and aging.

“Fecal Transplants Reverse Hallmarks of Aging in the Gut, Eyes, and Brain” by The University of East Anglia
- https://scitechdaily.com/fecal-transplants-reverse-hallmarks-of-aging-in-the-gut-eyes-and-brain/
“Fecal Microbiota Transfer Between Young and Aged Mice Reverses Hallmarks of the Aging Gut, Eye, And Brain” by Aimée Parker, Stefano Romano, Rebecca Ansorge, Asmaa Aboelnour, Gwenaelle Le Gall, George M. Savva, Matthew G. Pontifex, Andrea Telatin, David Baker, Emily Jones, David Vauzour, Steven Rudder, L. Ashley Blackshaw, Glen Jeffery & Simon R. Carding
- https://microbiomejournal.biomedcentral.com/articles/10.1186/s40168-022-01243-w

Search and rescue roaches.

“Robotised insects may search collapsed buildings for survivors” by The Economist
- https://www.economist.com/science-and-technology/robotised-insects-may-search-collapsed-buildings-for-survivors/21808326
“S'pore team turning cockroaches into life-saving cyborg bugs at disaster sites” by Clara Chong
- https://www.straitstimes.com/singapore/spore-team-turning-cockroaches-into-life-saving-cyborg-bugs-at-disaster-sites

Mushroom talks.

“Language of Fungi Derived From Their Electrical Spiking Activity” by Andrew Adamatzky
- https://royalsocietypublishing.org/doi/10.1098/rsos.211926
“Mushrooms may Communicate with Each Other Using Electrical Impulses” by Elizabeth Gamillo
- https://www.smithsonianmag.com/smart-news/mushrooms-may-communicate-with-each-other-using-electrical-impulses-180979889/
“Fungi Appear to Talk in a Language Similar to Humans” by Hannah Osborne
- https://www.newsweek.com/fungi-language-communication-talk-similar-humans-1695146
“The Fungus Among Us May Have Their Own Mushroom Language” by Melissa Truth Miller
- https://nerdist.com/article/mushrooms-fungus-may-communicate-via-language-50-words/
“Do Trees Talk to Each Other?” by Richard Grant
- https://www.smithsonianmag.com/science-nature/the-whispering-trees-180968084/

Find episode transcripts here: https://curiosity-daily-4e53644e.simplecast.com/episodes/poop-of-youth-robot-roaches-chatty-fungus

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Nostalgia Blocks Pain, Uploaded Brains, Sand vs. Nanoplastic Aug 11, 2022

Show notes

Listen in to hear how nostalgic thoughts can be a method of physical pain relief, the recent progress made in the effort to one day upload our minds to the digital world, and how getting nanoplastic out of our drinking water could be as simple as sand!

Memories can be pain free.

“Scientists Find a Surprising Connection Between Nostalgia and Pain Relief” by Nick Keppler
- https://www.inverse.com/mind-body/nostalgia-pain-relief-connection
“Nostalgia Can Reduce Perception of Pain, Study Shows” by Lauren Kent
- https://www.cnn.com/2022/03/28/health/nostalgia-pain-relief-study-wellness/index.html

Digital thoughts.

“Could We Really Use Science To Upload Our Minds?" by Tara Yarlagadda
- https://www.inverse.com/science/upload-amazon-real-science
“Will We Ever Be Able to Upload Our Brains?” By K. Thor Jensen
- https://www.pcmag.com/news/will-we-ever-be-able-to-upload-our-brains
“Elon Musk says humans could eventually download their brains into robots — and Grimes thinks Jeff Bezos would do it” by Megan Sauer
- https://www.cnbc.com/2022/04/08/elon-musk-humans-could-eventually-download-their-brains-into-robots.html
“100 Trillion Connections: New Efforts Probe and Map the Brain's Detailed Architecture” by Carl Zimmer
- https://www.scientificamerican.com/article/100-trillion-connections/
“Ted Williams Frozen In Two Pieces” by Associated Press
- https://www.cbsnews.com/news/ted-williams-frozen-in-two-pieces/

Water without plastic.

“Water Treatment Plants Would Be Ready For The Removal Of Nanoplastics” by Andri Bryner
- https://www.eawag.ch/en/news-agenda/news-portal/news-detail/water-treatment-plants-would-be-ready-for-the-removal-of-nanoplastics
“Nanoplastics Removal During Drinking Water Treatment: Laboratory- And Pilot-Scale Experiments And Modeling” by Gerardo Pulido-Reyesa, Leonardo Magherini, Carlo Bianco, Rajandrea Sethi, Ursvon Guntenac, Ralf Kaegi, and Denise M. Mitranod
- https://www.sciencedirect.com/science/article/pii/S0304389422008007?via%3Dihub
“How Does a Sand Filter Work?” by Joshua Reijnen
- https://royalbrinkman.com/knowledge-center/technical-projects/water-filter-technologies-horticulture/sand-filter
“Methodologies to Characterize, Identify and Quantify Nano- And Sub-Micron Sized Plastics in Relevant Media For Human Exposure: A Critical Review” by Carlo Roberto de Bruin, Eva de Rijke, Annemarie P. van Wezel, and A. Astefanei.
- https://pubs.rsc.org/en/content/articlehtml/2022/va/d1va00024a

Find episode transcripts here:https://curiosity-daily-4e53644e.simplecast.com/episodes/nostalgia-blocks-pain-uploaded-brains-sand-vs-nanoplastic

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A.I. and Angina, Undead Tigers, Electrici-sweets Aug 10, 2022

Show notes

Discover how artificial intelligence can help prevent heart attacks, how scientists are working to bring an extinct species back from the dead, and how sugar in our own body might soon make electricity!

Heart attack prevention.

“AI Predicts If and When Someone Will Experience Cardiac Arrest” by Jill Rosen
- https://hub.jhu.edu/2022/04/07/trayanova-artificial-intelligence-cardiac-arrhythmia/
“Arrhythmic sudden death survival prediction using deep learning analysis of scarring in the heart” by Dan M. Popescu, et al.
- https://www.nature.com/articles/s44161-022-00041-9
“Heart Attack” by Mayo Clinic
- https://www.mayoclinic.org/diseases-conditions/heart-attack/symptoms-causes/syc-20373106
“How the body regulates scar tissue growth after heart attacks” by University of California - Los Angeles Health Sciences
- https://www.sciencedaily.com/releases/2020/07/200706100815.htm
“Artificial intelligence in healthcare: past, present and future” by Fei Jiang, et al.
- https://svn.bmj.com/content/svnbmj/2/4/230.full.pdf

Back from the dead.

“De-Extinction Scientists Are Planning To Bring a Long-Lost 'Tiger' Species Back to Life” by Orlando Jenkinson
- https://www.newsweek.com/de-extinction-scientists-planning-long-lost-tiger-species-life-1683993
“Thylacine” by The Australian Musem
- https://australian.museum/learn/australia-over-time/extinct-animals/the-thylacine/
“Pathways to de-extinction: how close can we get to resurrection of an extinct species?” by Beth Shapiro
- https://besjournals.onlinelibrary.wiley.com/doi/full/10.1111/1365-2435.12705
“The Roar of the Tiger is Fading from Our Planet” by Project CAT
- https://projectcat.discovery.com/

Sugar: it’s electric.

“Ultrathin fuel cell uses the body’s own sugar to generate electricity” by Jennifer Chu
- https://news.mit.edu/2022/glucose-fuel-cell-electricity-0512
“This Ultrathin Fuel Cell Uses Your Body’s Sugar to Make Electricity” by Tony Ho Tran
- https://news.yahoo.com/ultrathin-fuel-cell-uses-body-152533024.html#:~:text=The%20ultrathin%20fuel%20cell%20is,on%20your%20body's%20natural%20sugars.&text=The%20team%20behind%20the%20new,like%20artificial%20hearts%20or%20pacemakers.
“There’s No Such Thing as a Sugar Rush, According to Science” by Joshua A. Krisch
- https://www.fatherly.com/health-science/theres-no-thing-sugar-rush-according-science
“Ultrathin Fuel Cells Could Use Your Body’s Sugar to Power Implants” by Sascha Brodsky
- https://www.lifewire.com/ultrathin-fuel-cells-could-use-your-bodys-sugar-to-power-implants-5272565

Find episode transcripts here: https://curiosity-daily-4e53644e.simplecast.com/episodes/ai-and-angina-undead-tigers-electrici-sweets

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The Explorers Club - An Interview With Joe Rohde Aug 05, 2022

Show notes

Hear from Joe Rohde, a former Disney Imagineer and the Experience Architect for Virgin Galactic. As an Imagineer, he was the leader of the team behind Disney’s Animal Kingdom. Joe is also Co-Chair of the Explorers Club 50 program.

Joe Rohde Interview from 4/23/22

Find episode transcripts here: https://curiosity-daily-4e53644e.simplecast.com/episodes/the-explorers-club-an-interview-with-joe-rohde

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Healing Hearing Hairs, Sun Phones, Chicken Gods Aug 04, 2022

Show notes

Hear about a new treatment that may be able to reverse hearing loss, how new solar energy storage technology could eventually power our phones, and the surprisingly grand history of chickens.

Reversing hearing loss.

“Reversing hearing loss with regenerative therapy” by Zach Winn
- https://news.mit.edu/2022/frequency-therapeutics-hearing-regeneration-0329
“What are Progenitor Cells? Exploring Neural, Myeloid and Hematopoietic Progenitor Cells” by Nicole Gleichmann
- https://www.technologynetworks.com/cell-science/articles/what-are-progenitor-cells-exploring-neural-myeloid-and-hematopoietic-progenitor-cells-329519
“Quick Statistics About Hearing” by the National Institute on Deafness and Other Communication Disorders
- https://www.nidcd.nih.gov/health/statistics/quick-statistics-hearing
“PCA Approach” and “About Hearing Loss” by Frequency Therapeutics
- https://www.frequencytx.com/science/pca-approach/
- https://www.frequencytx.com/hearing-loss/about-hearing-loss/
“FX-322 in Adults With Acquired Sensorineural Hearing Loss” by Frequency Therapeutics Clinical Trial
- https://clinicaltrials.gov/ct2/show/NCT05086276

Phone charger, but make it the sun.

“Converting solar energy to electricity on demand” by Chalmers University of Technology
- https://techxplore.com/news/2022-04-solar-energy-electricity-demand.html
“For a Better Future” by The MOST Solar Project
- https://mostsolarproject.eu/
“Molecular solar thermal (MOST) energy storage and release system” by Kasper Moth-Poulsen, et al.
- https://pubs.rsc.org/en/content/articlelanding/2012/ee/c2ee22426g
“Solar Energy: Benefits and Drawbacks” by Matthew Johnston
- https://www.investopedia.com/articles/investing/053015/pros-and-cons-solar-energy.asp

Chicken breeding.

“The biocultural origins and dispersal of domestic chickens” by Joris Peters, Ophélie Lebrasseur, Evan K. Irving-Pease, Ptolemaios Dimitrios Paxinos, Julia Best, Riley Smallman, Cécile Callou, Armelle Gardeisen, Simon Trixl, Laurent Frantz, Naomi Sykes, Dorian Q. Fuller, and Greger Larson.
- https://www.pnas.org/doi/full/10.1073/pnas.2121978119
“A new origin story for domesticated chickens starts in rice fields 3,500 years ago” by Bruce Bower.
- https://www.sciencenews.org/article/chicken-domestication-bones-origin-asia-rice-fields-exotic-animals
“Redefining the timing and circumstances of the chicken's introduction to Europe and north-west Africa” by Julia Best, Sean Doherty, Ian Armit, Zlatozar Boev, Lindsey Büster, Barry Cunliffe, Alison Foster, Ben Frimet, Sheila Hamilton-Dyer, Tom Higham, Ophélie Lebrasseur, Holly Miller, Joris Peters, Michaël Seigle, Caroline Skelton, Rob Symmons, Richard Thomas, Angela Trentacoste, Mark Maltby, Greger Larson, and Naomi Sykes
- https://www.cambridge.org/core/journals/antiquity/article/redefining-the-timing-and-circumstances-of-the-chickens-introduction-to-europe-and-northwest-africa/0797DAA570D51D988B0514C37C2EC534

Find episode transcripts here: https://curiosity-daily-4e53644e.simplecast.com/episodes/healing-hearing-hairs-sun-phones-chicken-gods

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Murdering Murder Hornets, ADHD & Hoarding, Pain Pill Ills Aug 03, 2022

Show notes

Learn about how Japanese honey bees protect themselves from murder hornets, how a new link has been discovered between ADHD and hoarding disorder, and how your over the counter pain meds, might actually be making your pain worse!

Honey avoiding murder.

“Key genes enable Japanese honey bees to roast hornets” by Proceedings of the National Academy of Sciences of the United States of America
- https://www.pnas.org/post/journal-club/key-genes-enable-japanese-honey-bees-roast-hornets
“Murder Hornets vs. Honeybees: A Swarm of Bees Can Cook Invaders Alive” by Mike Baker
- https://www.nytimes.com/2020/05/03/us/murder-hornets-asian-giant-hornet-bees.html

Does having ADHD mean you’re more likely to be a hoarder?

“A Curious Link Between Inattention and Hoarding Could Lead to New ADHD Therapies” by Sarah Sloat”
- https://www.inverse.com/mind-body/adhd-hoarding
“Hoarding: People With ADHD are More Likely to Have Problems - New Research” by Sharon Morein
- https://theconversation.com/hoarding-people-with-adhd-are-more-likely-to-have-problems-new-research-176211

Hold the meds.

“Anti-inflammatory Medications Raise Risk of Chronic Back Pain in Patients” by Joseph Cariz
- https://www.aaas.org/news/anti-inflammatory-medications-raise-risk-chronic-back-pain-patients
“Acute inflammatory response via neutrophil activation protects against the development of chronic pain” by Marc Parisien, Lucas V. Lima, Concetta Dagostino, Nehme El-Hachm, Gillian L. Drury, Audrey V. Grant, Jonathan Huising, Vivek Verma, Carolina B. Meloto, Jaqueline R. Silva, Gabrielle G.S. Dutra, Teodora Markova, Hong Dang, Philippe A. Tessier, Gary D. Slade, Andrea G. Nackley, Nader Ghasemlou, Jeffrey S. Mogil, Massimo Allegri, and Luda Diatchenko.
- https://www.science.org/doi/10.1126/scitranslmed.abj9954

Find episode transcript here: https://curiosity-daily-4e53644e.simplecast.com/episodes/murdering-murder-hornets-adhd-hoarding-pain-pill-ills

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