Curbside Consults

Latest Episodes:

NEJM Editorial Fellowship 2018/2019 Wrap-Up Oct 16, 2019

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Together with Dr. David Harrington, 2018/2019 NEJM Editorial Fellows Angie, Angela, and Amanda summarize and wrap up the NEJM experience.

Statistical Review – Missing Data with Dr. David Harrington Sep 19, 2019

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Missing data are common in randomized, controlled trials. Why does this happen? How do we interpret these missing data? In this episode of Curbside Consults, Dr. David Harrington, statistical editor at the NEJM, joins us for a discussion on missing data and how to interpret missing data in studies.

Osteoporosis with Dr. Clifford J. Rosen Sep 04, 2019

Show notes

Osteoporosis affects more than 10 million people living in the United States. Although a number of medications are available for treatment of osteoporosis, it remains undertreated. In this episode of Curbside Consults, Dr. Clifford J. Rosen, Professor of Medicine at Tufts University School of Medicine and Associate Editor at the NEJM, joins us to...

Statistical Review – Observational Studies with Dr. David Harrington Aug 22, 2019

Show notes

Although randomized controlled trials get much of the attention in journal club, observational studies allow researchers to ask questions that may not be possible with RCTs. In this episode of Curbside Consults, we discuss the strengths and limitations of large observational studies and how to critically appraise them.

The Evolution of Opioid Prescription Habits and Approaches to Opioid Prescribing with Dr. Scott Hadland Aug 07, 2019

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In the current era of the opioid epidemic, what role do opioid prescriptions play? With all the scrutiny physicians face when prescribing opioids, what can trainees do to be safe and thoughtful prescribers? Dr. Scott Hadland, Assistant Professor of Pediatrics at Boston University School of Medicine and on the faculty of the Grayken Center for...

Statistical Review – Early Trial Cessation – When, Why and How to Interpret with Dr. David Harrington Jul 24, 2019

Show notes

Clinical trials can be stopped early for a range of reasons. But when that happens, it can be tricky to interpret the results and to understand the reasons why the trial was stopped in the first place. Join us in this episode of Curbside Consults with Dr. David Harrington, statistical editor at the NEJM, as we discuss...

Time Limits for Thrombolysis in Acute Ischemic Stroke with Dr. Steven Feske Jul 11, 2019

Show notes

Intravenous thrombolysis has been an essential component in the management of acute ischemic stroke. Current guidelines recommend that thrombolysis be administered within 3 hours of the onset of first neurologic symptoms. However, two recent trials published in NEJM challenge this time paradigm. In this episode of Curbside Consults...

Statistical Review – Pragmatic Trials with Dr. David Harrington Jun 26, 2019

Show notes

Practical or pragmatic trials are designed to show the effectiveness of an intervention in the complex clinical setting of daily practice. But what makes a trial pragmatic? Can a clinical trial ever be completely pragmatic? Join us in this episode of Curbside Consults with Dr. David Harrington, statistical editor at the NEJM, as we discuss the elements...

E-cigarettes: The Basics, Use in Smoking Cessation, and the Adolescent Epidemic with Dr. Jonathan Winickoff Jun 13, 2019

Show notes

The rise in popularity of e-cigarettes in the last 5 years has changed the landscape and language surrounding nicotine delivery, smoking cessation, and adolescent substance use. In this episode of Curbside Consults, Dr. Jonathan Winickoff, Professor of Pediatrics at Mass General Hospital for Children and Director of Pediatric Research...

Statistical Review – Composite Outcomes with Dr. David Harrington May 30, 2019

Show notes

Composite outcomes are frequently used as primary outcomes in randomized-controlled trials and observational studies. Why are they used? What are the limitations of their use? How are composite outcomes interpreted? Join us in this episode as Dr. David Harrington, statistical editor at the NEJM, helps breakdown composite outcomes.

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