Best Science Medicine Podcast - BS without the BS

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Latest Episodes:

Episode 598: Insomnia – hours of sleep is not the goal! – PART II Jan 28, 2025

In episode 598, James and Mike continue to talk with David Gardner about the issue of insomnia. We discuss his latest, very cool, Your Answers When Needing Sleep (YAWNS NB) randomized clinical trial. YAWNS was a pragmatic, open-label, minimum-contact, RCT where people with long-term use of benzodiazepines and current or past insomnia were randomly allocated to different mailed behavior change interventions or no intervention. They found that in people who got the intervention more of them stopped or reduced the dose of their benzodiazepines and more improved their sleep. Tune in for the numbers for this simple intervention.

Show Notes

The YAWNS NB trial

Booklets: order booklets via the Resource Centre

Sleepwell, a research and knowledge translation program based out of Dalhousie University in Halifax, includes tools, resources, and recommendations for patients, the public, and health care professionals.

Some features and resources to explore are:
Sleepwell stories (patient and health care professional video and written accounts)
Clinicians – short videos on how to use get what you need from the website for patient care, and CBT-I training options
Sleepwell recommends – vetted reviews and recommendations for self-help CBT-I programs
Sleeping pills – content to motivate and facilitate safely ending long-term use of sedatives
Tools – sleep diary, online sleep calculator (with guidance for time-in-bed restriction therapy), behaviour change tools (CBTi vs. Sleeping Pills)

Zopiclone’s residual effects on actual driving performance in a standardized test: a pooled analysis of age and sex effects in 4 placebo-controlled studies
Clin Ther 2014 Jan 1;36(1):141-50. doi: 10.1016/j.clinthera.2013.11.00

Episode 597: Insomnia – hours of sleep is not the goal! Jan 21, 2025

In episode 597, James and Mike invite David Gardner to talk in depth about the issue of insomnia. We talk about triggers, precipitating factors, acute and chronic insomnia, and chronic use of sleeping pills. We discuss Cognitive Behavioral Therapy for Insomnia (CBT-I) and how his team has developed a comprehensive website, Sleepwell, that provides patients and clinicians with great tools and recommendations for the self-care of chronic insomnia. Mike stays awake for the whole podcast and James only has a brief nap.

Show Notes

Visit https://mysleepwell.ca/

Episode 595: How to slow the flow: Combined oral contraceptives Jan 03, 2025

In episode 595, Mike and James invite Jennifer Young back to talk about the use of combined oral contraceptives for heavy menstrual bleeding (benign etiology) and see if they improve patient outcomes. They do! Have a listen to get all the numbers and see how they compare to using levonorgestrel-containing intrauterine devices or NSAIDs.

Show notes

Tools for Practice
1) How to Slow the Flow: Combined oral contraceptives
2) How to Slow the Flow: Tranexamic acid for heavy menstrual bleeding
3) How to Slow the Flow: Levonorgestrel intrauterine systems for heavy menstrual bleeding
4) How to Slow the Flow: NSAIDs for Heavy Menstrual Bleeding

Episode 594: Bumpin’ Up the Protection? RSV Vaccine in Pregnancy Dec 27, 2024

In episode 594, Mike and James invite Samantha Moe back to talk about the use of the RSV vaccine in pregnancy. The only way to have an informed conversation around this vaccine is to know the numbers. If you listen to the whole podcast, you’ll get all the numbers available to date.

Show notes
Tools for Practice
1)Bumpin’ Up the Protection? RSV Vaccine in Pregnancy

2) Preventing RSV Infections in Infants

3) Preventing RSV in the elderly

Episode 593: Tony Romo-sozumab: Winning touchdown in osteoporosis or interception for the loss? Dec 20, 2024

In episode 593, Mike and James invite Samantha Moe back to talk about a newer agent for osteoporosis. So, if you want to know all the evidence for romosozumab, tune in and all will be revealed about the benefits and harms.

Show notes
1) Tools for Practice
Tony Romo-sozumab: Winning touchdown in osteoporosis or interception for the loss?

2) FRAX site for Canada

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