This Week in Virology - Vincent Racaniello

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Latest Episodes:

TWiV Special: Long COVID and ME/CFS with David Tuller Jun 17, 2025

David Tuller returns to TWiV to discuss RFK Jr. and the trashing of American public health, rituximab and ME/CFS, The Sick Times, the Cochrane Mess, a Norwegian Long Covid trial, effort preference and more.

Host: Vincent Racaniello

Guest: David Tuller

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Links for this episode

MicrobeTV Discord Server
David Tuller writes at virology blog
CFS, a long tangled tale (virology blog)
The Sick Times
Norwegian Long COVID trial (virology blog)
Cochrane mess (virology blog)
Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content on TWiV should not be taken as medical advice.

TWiV 1227: How can antibody forget a pandemic? Jun 15, 2025

TWiV reviews the administrations dismantling of the committee that studies pandemic potential, firing of CDC vaccine advisory committee and replacing them with unqualified anti-vaxxers, zoonotic and sustained Mpox spread in Nigeria and Cameroon, and breadth of influenza A antibody cross-reactivity.

Hosts: Vincent Racaniello, Alan Dove, and Brianne Barker

Subscribe (free): Apple Podcasts, RSS, email

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Links for this episode

Support science education at MicrobeTV 2:39
NIH terminates pandemic preparedness committee (Science)
RFK Jr. fires all ACIP members (CNN)
RFK Jr. names dubious members of new ACIP (NPR)
Zoonotic and sustained Mpox spread in West Africa (Nature)
Breadth of influenza A antibody cross-reactivity (Nat Micro)
Letters read on TWiV 1227
Timestamps by Jolene Ramsey. Thanks!

Weekly Picks

Brianne – Accidental discovery in planetarium show Alan – Project Hail Mary Vincent – How to speak to a vaccine sceptic: research reveals what works

Listener Picks

James – Looking at the world through a microscope

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1226: Clinical update with Dr. Daniel Griffin Jun 14, 2025

In his weekly clinical update, Dr. Griffin with Vincent Racaniello in horror examine dismantling of public infrastructure for establishing vaccine guidelines, the creation of a autism taskforce by someone disciplined for practicing medicine without a license, the ongoing pertussis, bird flu and measles outbreaks, before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections the Wasterwater Scan dashboard, the effective of oseltamivir vs supportive care when one is hospitalized with influenza infection, whether or not the NB.1.8.1 should be included in the fall 2025 vaccines, approval of another anti-RSV monoclonal antibody for treatment in infants, immunization recommendations for COVID-19 vaccines, where to find PEMGARDA, results from the phase 3 randomized clinical trial of pemivibart, provides information for Columbia University Irving Medical Center’s long COVID treatment center, where to go for answers to your long COVID questions, how artery disease impacts SARS-CoV-2 infection outcomes, contacting your federal government representative to stop the assault on science and biomedical research and the recent public health programs that have been unfunded.

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Links for this episode

Vaccine Opponent Hired by RFK Jr. Scours Official Records for Link to Autism (Wall Street Journal)
Correcting our record (Salon)
You are FIRED! Kennedy removes all ACIP members, eyes replacement (CIDRAP)
UPI Investigates: The vaccine conflict…..investigative reporting? (UPI)
RFK Jr.: HHS Moves to Restore Public Trust in Vaccines…to avoid conflicts UGHHHH! (Wall Street Journal)
GREAT Vaccine advisory panel (Great Barrington Declaration)
National Vaccine Information Center (Wikipedia: National Vaccine Information Center)
Nonprofit organization 501(c) (Wikipedia)
Kennedy Announces Eight New Members of C.D.C. Vaccine Advisory Panel (NY Times)
Whooping cough deaths! (Kentucky. Gov)
Kentucky announces two pertussis deaths in infants this year (CIDRAP)
H5 bird flu: current situation (CDC: Avian Influenza)
Stability of influenza viruses in the milk of cows and sheep (medRxiv)
Wastewater for measles (WasterWater Scan)
Measles cases and outbreaks (CDC Rubeola)
Weekly measles and rubella monitoring (Government of Canada)
Canada’s Ontario province reports death of child from measles (Reuters)
Measles outbreaks continue with risk of holidays causing surge (gov.UK)
Measles (WHO)
Measles vaccine recommendations from NYP (jpg)
Get the FACTS about measles (NY State Department of Health)
Measles (CDC Measles (Rubeola))
Measles vaccine (CDC Measles (Rubeola))
Presumptive evidence of measles immunity (CDC)
Contraindications and precautions to measles vaccination (CDC)
Measles (CDC Measles (Rubeola)
Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America)
Deaths following vaccination: what does the evidence show (Vaccine)
Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
US respiratory virus activity (CDC Respiratory Illnesses)
Weekly surveillance report: clift notes (CDC FluView)
Respiratory virus activity levels (CDC Respiratory Illnesses)
Weekly surveillance report: clift notes (CDC FluView)
Oseltamivir Treatment vs Supportive Care for Seasonal Influenza Requiring Hospitalization (JAMA)
FDA-CDC-DOD: 2025-2046 influenza vaccine composition (FDA)
RSV: Waste water scan for 11 pathogens (WastewaterSCan)
US respiratory virus activity (CDC Respiratory Illnesses)
RSV-Network (CDC Respiratory Syncytial virus Infection)
Approval for Merck’s ENFLONSIA™ (clesrovimab-cfor) for Prevention of Respiratory Syncytial Virus (RSV) Lower Respiratory Tract Disease in Infants Born During or Entering Their First RSV Season (Merck)
Waste water scan for 11 pathogens (WastewaterSCan)
COVID-19 deaths (CDC)
COVID-19 national and regional trends (CDC)
COVID-19 variant tracker (CDC)
SARS-CoV-2 genomes galore (Nextstrain)
Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (biRxiV)
COVID-19 vaccine for 6 months, 12 years (CDC: childhood vaccination)
COVID-19 vaccine for65 years and older (CDC: Adult vaccination)
Where to get pemgarda (Pemgarda)
EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
Infusion center (Prime Fusions)
CDC Quarantine guidelines (CDC)
NIH COVID-19 treatment guidelines (NIH)
Drug interaction checker (University of Liverpool)
Infectious Disease Society guidelines for treatment and management (ID Society)
Molnupiravir safety and efficacy (JMV)
Convalescent plasma recommendation for immunocompromised (ID Society)
What to do when sick with a respiratory virus (CDC)
Managing healthcare staffing shortages (CDC)
Steroids,dexamethasone at the right time (OFID)
Anticoagulation guidelines (hematology.org)
Daniel Griffin’s evidence based medical practices for long COVID (OFID)
Long COVID hotline (Columbia : Columbia University Irving Medical Center)
The answers: Long COVID
Long-term outcomes of patients with pre-existing coronary artery disease after SARS-CoV-2 infection (eBioMedicine)
Reaching out to US house representative
Trump Budget Eliminates Funding for Crucial Global Vaccination Programs(NY Times)
Letters read on TWiV 1226
Dr. Griffin’s COVID treatment summary (pdf)
Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1225: Poultry flu and SARS-CoV-2 Jun 08, 2025

TWiV reviews the administration’s call for fools gold-standard science, NIH may publish in-house, avian influenza viruses in birds in China, and Omicron pathogenicity and immune responses.

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

Links for this episode

Support science education at MicrobeTV
Fool’s Gold Standard Science (Nature)
NIH may publish in-house (Stat News)
Diversity of H9N2 in China (Nat Micro)
Omicron and immunity (Cell Rep)
Letters read on TWiV 1225
Timestamps by Jolene Ramsey. Thanks!

Weekly Picks

Kathy – mSphere virus species names standardization Rich – Real Tides & Currents Graph HD Alan – Invasive termites spreading from privately owned boats Vincent – Entomologist Answers Insect Questions

Listener Picks

Gerry – Citations Needed podcast 221: Anti-science mugging Joyrell – Mayday: Air Disaster Favorite one, two, three, for Vincent

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1224: Clinical update with Dr. Daniel Griffin Jun 07, 2025

In his weekly clinical update, Dr. Griffin with Vincent Racaniello in dismay examine the MAHA-Make America Health Again-report and its inclusion of fictious studies or “Creative literature degree Medical Science writing”, RFK Jr contradicted by the CDC for COVID-19 vaccine recommendations for children, reduction in MMR vaccine coverage, the ongoing bird flu and measles outbreaks, how the General Accounting Office instructed HHS to fix deficiencies in infectious disease testing before the next pandemic, before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections the Wasterwater Scan dashboard, whether or not the NB.1.8.1 should be included in the fall 2025 vaccines approval of Moderna’s mNEXSPIKE vaccine for fall 2025, childhood immunization recommendations for COVID-19 vaccines, where to find PEMGARDA, results from the phase 3 randomized clinical trial of pemivibart, provides information for Columbia University Irving Medical Center’s long COVID treatment center, where to go for answers to your long COVID questions, the identification of an association between FOXP4 and long COVID and contacting your federal government representative to stop the assault on science and biomedical research.

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

Links for this episode

The MAHA report (The White House)
White House Health Report Included Fake Citations (NY Times)
C.D.C. Contradicts Kennedy and Keeps Advice That Children May Get Covid Shots (NY TImes)
CDC revises recommendation for COVID vaccines in kids (CIDRAP)
Exclusive: CDC Expert resigns from COVID vaccines advisory role (Reuters)
Trends in County-Level MMR Vaccination Coverage in Children in the United States (JAMA Network)
U.S. Cancels Contract With Moderna to Develop Bird Flu Vaccine (NY Times)
Canada Wants to Kill 400 Ostriches. Kennedy and Dr. Oz Want to Save Them. (NY Times)
Confirmations of Highly Pathogenic Avian Influenza in Commercial and Backyard Flocks (USDA: Animal and Plant Health Inspection Service)
H5 bird flu: current situation (CDC: Avian Influenza)
Bird flu (CDC: Avian Influenza)
H5N1 avian flu strikes another Arizona layer farm (CIDRAP)
Bird flu outbreak kills 95% of Hickman’s Arizona chickens, closes West Valley farms (AZCentral)
Wastewater for measles (WasterWater Scan)
Additional Denver Resident Tests Positive forMeasles (Denver: The Mile High City)
Health officials alert public of potential measles exposure at Denver International Airport and nearby hotel (Colorado: Department of public health and environment)
Colorado announces another measles case linked to Turkish Airlines flight (CIDRAP)
Measles cases and outbreaks (CDC Rubeola)
Weekly measles and rubella monitoring (Government of Canada)
Measles (WHO)
Measles vaccine recommendations from NYP (jpg)
Get the FACTS about measles (NY State Department of Health)
Measles (CDC Measles (Rubeola))
Measles vaccine (CDC Measles (Rubeola))
Presumptive evidence of measles immunity (CDC)
Contraindications and precautions to measles vaccination (CDC)
Measles (CDC Measles (Rubeola))
Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America)
Deaths following vaccination: what does the evidence show (Vaccine)
Public Health Preparedness: HHS Needs a Coordinated National Approach for Diagnostic Testing for Pandemic Threats (GAO: US Government Accountability Office)
GAO to HHS: Fix ‘persistent deficiencies’ in infectious-disease testing before next pandemic (CIDRAP)
Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
US respiratory virus activity (CDC Respiratory Illnesses)
Weekly surveillance report: clift notes (CDC FluView)
Respiratory virus activity levels (CDC Respiratory Illnesses)
Weekly surveillance report: clift notes (CDC FluView)
FDA-CDC-DOD: 2025-2046 influenza vaccine composition (FDA)
RSV: Waste water scan for 11 pathogens (WastewaterSCan)
US respiratory virus activity (CDC Respiratory Illnesses)
RSV-Network (CDC Respiratory Syncytial virus Infection)
Waste water scan for 11 pathogens (WastewaterSCan)
COVID-19 deaths (CDC)
COVID-19 national and regional trends (CDC)
COVID-19 variant tracker (CDC)
SARS-CoV-2 genomes galore (Nextstrain)
Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (biRxiV)
mNEXSPIKE is now approved and coming this fall (mNEXSPIKE)
FDA approval for mNEXSPIKE (moderna)
COVID-19 vaccine for 6 months, 12 years (CDC: childhood vaccination)
COVID-19 vaccine for65 years and older (CDC: Adult vaccination)
ACIP Shared Clinical Decision-Making Recommendations (CDC: Advisory Committee on Immunization Practices(ACIP))
Safety and Efficacy of Pemivibart, a Long-Acting Monoclonal Antibody, for Prevention of Symptomatic COVID-19 (CID)
Where to get pemgarda (Pemgarda)
EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
Infusion center (Prime Fusions)
CDC Quarantine guidelines (CDC)
NIH COVID-19 treatment guidelines (NIH)
Drug interaction checker (University of Liverpool)
Infectious Disease Society guidelines for treatment and management (ID Society)
Molnupiravir safety and efficacy (JMV)
Convalescent plasma recommendation for immunocompromised (ID Society)
What to do when sick with a respiratory virus (CDC)
Managing healthcare staffing shortages (CDC)
Steroids,dexamethasone at the right time (OFID)
Anticoagulation guidelines (hematology.org)
Daniel Griffin’s evidence based medical practices for long COVID (OFID)
Long COVID hotline (Columbia : Columbia University Irving Medical Center)
The answers: Long COVID
Genome-wide association study of long COVID (Nature Genetics)
Reaching out to US house representative
Letters read on TWiV 1224
Dr. Griffin’s COVID treatment summary (pdf)
Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1223: Someone is guano be sick Jun 01, 2025

TWiV reviews RFK Jr.”s MAGA report with non-existent literature citations, a new fungus that could further devastate North American bats, surveillance of avian influenza viruses through bird guano in remote regions, and the receptor for HKU5 coronaviruses is ACE2 from Pipistrellus abramus bats.

Hosts: Vincent Racaniello, Kathy Spindler, and Brianne Barker

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

Links for this episode

Support science education at MicrobeTV
Bad citations in MAGA report (Med Exp)
Another fungus for North American bats (NY Times)
Surveillance of avian influenza through bird guano (Nat Commun)
ACE2 from Pipistrellus bats is receptor for HKU5 coronaviruses (Nat Commun)
Letters read on TWiV 1223
Timestamps by Jolene Ramsey. Thanks!

Weekly Picks

Brianne – New mutation found in orange cats Kathy – Middle schooler’s STEM project leads to a bacterium with antibiotic activity and to an anti-cancer compound Vincent – Elon Musk’s Legacy Is Disease, Starvation and Death

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1222: Clinical update with Dr. Daniel Griffin May 31, 2025

In his weekly clinical update, Dr. Griffin with Vincent Racaniello discusses vaccination trends, the changes COVID-19 vaccine recommendations for children and pregnant women, easing of vaccination exemptions in Texas, the ongoing measles outbreak globally before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections the Wasterwater Scan dashboard, whether or not the NB.1.8.1 should be included in the fall 2025 vaccines and concern as confirmed diagnosis of COVID-19 rise here and in China, different mechanisms by which to reduce transmission of respiratory pathogens, the May 22 VRBPAC COVID-19 vaccine meeting, where to find PEMGARDA, prolonged steroid and antibiotic therapies, provides information for Columbia University Irving Medical Center’s long COVID treatment center, where to go for answers to your long COVID questions, how spike protein may alter mast cells and the immune response and contacting your federal government representative to stop the assault on science and biomedical research.

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

Links for this episode

Vaccination trends (CDC: Respiratory Illnesses)
Weekly COVID-19 Vaccination Dashboard (CDC: COVIDVaxView)
RFK Jr ends coronavirus shot recommendation for healthy children and pregnant women (Washington Post)
Characteristics of Children Ages 1–17 Who Died of COVID-19 in 2020–2022 in the United States (American Academy of Pediatrics)
RFK Jr.’s War on Children (Paul Offit: Beyond the Noise)
AAP analyzes pediatric COVID-19 hospitalizations from 2020-’24 (American Academy of Pediatrics)
COVID-19–Associated Hospitalizations among Children and Adults — COVID-NET (CDC: National Center for Immunizations and Respiratory Diseases)
COVID-19–Associated Hospitalizations among Children and Adults — COVID-NET (CDC: National Center for Immunizations and Respiratory Diseases)
Long COVID in Children (CDC: NCHS)
Long COVID Prevalence and Associated Activity Limitation in US Children (JAMA Pediatrics)
The C.D.C. Now Says Healthy Kids Don’t Need Covid Shots. Is That True? (NY Times)
U.S. Will No Longer Recommend Covid Shots for Children and Pregnant Women (NY TImes)
Gregg Abbott (AP News)
US school-entry vaccination rates fall as exemptions keep rising (AP News)
Whooping cough cases are rising again in the US (AP News)
Amid measles outbreak, Texas is poised to make vaccine exemptions for kids easier (AP News)
Cardiac Events in Adults Hospitalized for Respiratory Syncytial Virus vs COVID-19 or Influenza (JAMA Network Open)
USDA reported H5N1 bird flu detection in wild birds (CDC: Avian Influenza)
USDA reported H5N1 in poultry (CDC: Avian Influenza)
HPAI Confirmed Cases in Livestock (USDA Animal and Plant Health Inspections Service)
H5 bird flu: current situation (CDC: Avian Influenza)
Bird flu (CDC: Avian Influenza)
Measles cases and outbreaks (CDC Rubeola)
Weekly measles and rubella monitoring (Government of Canada)
Measles (WHO)
Measles vaccine recommendations from NYP (jpg)
Get the FACTS about measles (NY State Department of Health)
Measles (CDC Measles (Rubeola))
Measles vaccine (CDC Measles (Rubeola))
Presumptive evidence of measles immunity (CDC)
Contraindications and precautions to measles vaccination (CDC)
Measles (CDC Measles (Rubeola)
Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
Measles Vaccination: Know the Facts(ISDA: Infectious Diseases Society of America)
Deaths following vaccination: what does the evidence show (Vaccine)
Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
US respiratory virus activity (CDC Respiratory Illnesses)
Weekly surveillance report: clift notes (CDC FluView)
Respiratory virus activity levels (CDC Respiratory Illnesses)
Weekly surveillance report: clift notes (CDC FluView)
FDA-CDC-DOD: 2025-2046 influenza vaccine composition (FDA)
RSV: Waste water scan for 11 pathogens (WastewaterSCan)
US respiratory virus activity (CDC Respiratory Illnesses)
RSV-Network (CDC Respiratory Syncytial virus Infection)
Respiratory syncytial virus: an under-recognized healthcare-associated infection (Infection Control & Hospital Epidemiology)
Waste water scan for 11 pathogens (WastewaterSCan)
COVID-19 deaths (CDC)
COVID-19 national and regional trends (CDC)
COVID-19 variant tracker (CDC)
SARS-CoV-2 genomes galore (Nextstrain)
Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (biRxiV)
New Covid variant NB.1.8.1 detected at US airports amid rise in cases
U.S. reports cases of new COVID variant NB.1.8.1 behind surge in China (CBS News)
WHO TAG-VE Risk Evaluation for SARS-CoV-2 Variant Under Monitoring: NB.1.8.1 (WHO)
New COVID variant NB.1.8.1 detected at US airports amid rise in cases (The Economic Times: News)
Infection Control Guidance: SARS-CoV-2 (CDC: COVID-19)
Isolating the burden of transmission-based precautions for COVID-19 (Infection Control & Hospital Epidemiology)
A pilot study of coughing into the shirt to disrupt respiratory pathogen transmission (International Journal of Emergency Medicine)
Hybrid B- and T-Cell Immunity Associates With Protection Against Breakthrough Infection After Severe Acute Respiratory Syndrome Coronavirus 2 Vaccination in Avon Longitudinal Study of Parents and Children (ALSPAC) Participants (JID)
FDA panel is split on updates to COVID shots as questions loom for fall vaccinations(AP News)
COVID-19 Vaccines (2025-2026 Formula) for Use in the United States Beginning in Fall 2025(FDA)
Interim Clinical Considerations for Use of COVID-19 Vaccines in the United States (CDC: COVID-19)
Where to get pemgarda (Pemgarda)
EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
Infusion center (Prime Fusions)
CDC Quarantine guidelines (CDC)
NIH COVID-19 treatment guidelines (NIH)
Clinical effectiveness of oral antiviral treatment for non-hospitalized high-risk patients with COVID-19 during Omicron JN.1 subvariant wave(Pneumonia)
Drug interaction checker (University of Liverpool)
Infectious Disease Society guidelines for treatment and management (ID Society)
A Systematic Review and Meta-analysis of the Effectiveness of Remdesivir to Treat Severe Acute Respiratory Syndrome Coronavirus 2 in Hospitalized Patients (CID)
Molnupiravir safety and efficacy (JMV)
Convalescent plasma recommendation for immunocompromised (ID Society)
What to do when sick with a respiratory virus (CDC)
Managing healthcare staffing shortages (CDC)
Steroids,dexamethasone at the right time (OFID)
Anticoagulation guidelines (hematology.org)
Tocilizumab, sarilumab and anakinra in critically ill patients with COVID-19 (Thorax)
Daniel Griffin’s evidence based medical practices for long COVID (OFID)
Long COVID hotline (Columbia : Columbia University Irving Medical Center)
The answers: Long COVID
Spike proteins of coronaviruses activate mast cells for degranulation via stimulating Src/PI3K/AKT/Ca2+ intracellular signaling cascade (Journal of Virology)
Reaching out to US house representative
Letters read on TWiV 1222
Dr. Griffin’s COVID treatment summary (pdf)
Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1221: Nonsense mediated decay May 25, 2025

TWiV reviews cuts in National Science Foundation budgets, cuts to Harvard University grants, judge blocks ban on Harvard enrolling international students, DOGE ordered cuts of NIH grants, endemic coronavirus infection induces Fc receptor binding antibodies to SARS-CoV-2, and inherited IFNAR1 deficiency causing adverse reactions to measles and yellow fever infectious vaccines.

Hosts: Vincent Racaniello, Alan Dove, and Angela Mingarelli

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

Links for this episode

Support science education at MicrobeTV
NSF funding cut to lowest level (NY Times)
1,000 grants cut at Harvard University (Nature)
Administration ban on international students at Harvard blocked (CNN)
DOGE killed NIH grants (Nature)
Endemic coronavirus infection induces FcR binding antibodies to SARS-CoV-2 (J Virol)
IFNAR1 deficiency and severe reaction to measles and yellow fever vaccines (J Exp Med)
Letters read on TWiV 1221
Timestamps by Jolene Ramsey. Thanks!

Weekly Picks

Angela – Contact lenses that give people infrared vision — even with their eyes shut (one, two) Alan – Autocrats are afraid of you – see the graphic, especially. Vincent – How One Company Secretly Poisoned The Planet

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1220: Clinical update with Dr. Daniel Griffin May 24, 2025

In his weekly clinical update, Dr. Griffin with Vincent Racaniello debate the changes in FDA vaccine approval policy especially how it is applied to COVID-19 vaccines and restricts vaccine availability/usage and Novavax’s vaccine, mpox on surfaces and in the air, “bird flu”, the ongoing measles outbreak globally before Dr. Griffin reviews recent statistics on RSV, benefits of vaccination for infants, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, the high number of childhood deaths during this “flu” season, the May 22 VRBPAC COVID-19 vaccine meeting, where to find PEMGARDA, prolonged steroid and antibiotic therapies, provides information for Columbia University Irving Medical Center’s long COVID treatment center, where to go for answers to your long COVID questions, cognitive impairment in long COVID and contacting your federal government representative to stop the assault on science and biomedical research.

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

Links for this episode

FDA to issue new vaccine approval guidance amid questions over coronavirus shots (Washington Post)
FDA vaccine committee meeting(Reuters)
Evidence-based approach to COVID-19 vaccination (NEJM)
FDA CBER townhall: new COVID019 vaccination approval mechanism (YouTube)
FDA poised to restrict access to COVID vaccines, our own Dr. Griffin is cited! (NY Times)
Novavax approval letter (FDA)
We giveth and taketh away: Novavax approved but restricted use (AP News)
FDA approves Novavax COVID vaccine with stricter new conditions (NY Times)
History behind public health falsehoods– vaccine and autism (NPR)
Making vaccines less accessible-RFK Jr making MAHA! (PBS News Hour)
Kenneday says DO NOT to take medical advice from him, the HHS secretary…hummmm (NY Times)
Staying up to date with COVID-19 vaccines (CDC: COVID-19)
How science lost America’s trust and surrendered health policy to skeptics (WSJ)
HHS stops recommendation of COVID-19 shots for children and pregnant women (Reuters)
No more routine COVID-19 vaccines for children and pregnant women (WSJ)
House to investigate Pfizer for allegedly delaying COVID-19 vaccines (Reuters)
Statement on the antigen composition of COVID-19 vaccines (WHO)
WHO advisers say current strains OK for COVID vaccine production (CIDRAP)
We can’t remain indifferent to suffering: Catholic Church now champions HPV vaccination (DailyNation)
Air and surface sampling for mpox in UK (Eurosurveillance)
Researchers report mpox DNA, live virus on surfaces and in air from patients’ rooms(CIDRAP)
USDA reported H5N1 bird flu detection in wild birds (CDC: Avian Influenza)
USDA reported H5N1 in poultry (CDC: Avian Influenza)
HPAI Confirmed Cases in Livestock(USDA Animal and Plant Health Inspections Service)
H5 bird flu: current situation (CDC: Avian Influenza)
Bird flu (CDC: Avian Influenza)
Measles cases and outbreaks (CDC Rubeola)
Measles and rubella weekly monitoring report: (Government of Canada)
Measles vaccine recommendations from NYP (jpg)
Get the FACTS about measles (NY State Department of Health)
Measles (CDC Measles (Rubeola)
Measles vaccine (CDC Measles (Rubeola)
Presumptive evidence of measles immunity (CDC)
Contraindications and precautions to measles vaccination (CDC)
Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
Measles Vaccination: Know the Facts(ISDA: Infectious Diseases Society of America)
Deaths following vaccination: what does the evidence show (Vaccine)
Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
US respiratory virus activity (CDC Respiratory Illnesses)
Weekly surveillance report: clift notes (CDC FluView)
Respiratory virus activity levels (CDC Respiratory Illnesses)
Weekly surveillance report: clift notes (CDC FluView)
FDA-CDC-DOD: 2025-2046 influenza vaccine composition (FDA)
RSV: Waste water scan for 11 pathogens (WastewaterSCan)
US respiratory virus activity (CDC Respiratory Illnesses)
RSV-Network (CDC Respiratory Syncytial virus Infection)
Waste water scan for 11 pathogens (WastewaterSCan)
COVID-19 deaths (CDC)
COVID-19 national and regional trends (CDC)
COVID-19 variant tracker (CDC)
SARS-CoV-2 genomes galore (Nextstrain)
Interim Clinical Considerations for Use of COVID-19 Vaccines in the United States (CDC: COVID-19)
COVID-19 vaccine VRBPAC May 22 (FDA)
Where to get pemgarda (Pemgarda)
EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
Infusion center (Prime Fusions)
CDC Quarantine guidelines (CDC)
NIH COVID-19 treatment guidelines (NIH)
Drug interaction checker (University of Liverpool)
Infectious Disease Society guidelines for treatment and management (ID Society)
Molnupiravir safety and efficacy (JMV)
Convalescent plasma recommendation for immunocompromised (ID Society)
What to do when sick with a respiratory virus (CDC)
When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)
Managing healthcare staffing shortages (CDC)
Steroids,dexamethasone at the right time (OFID)
The clinical impact of prolonged steroid therapy in severe COVID-19 patients (BMC Pulmonary Medicine)
Anticoagulation guidelines (hematology.org)
Antibiotic Treatment in Patients Hospitalized for Nonsevere COVID-19 (JAMA Network Open)
Daniel Griffin’s evidence based medical practices for long COVID (OFID)
Long COVID hotline (Columbia : Columbia University Irving Medical Center)
The answers: Long COVID
Self-reported health, neuropsychological tests and biomarkers in fully recovered COVID-19 patients vs patients with post-COVID cognitivesymptoms (PLoS One)
Vortioxetine for Cognitive Impairment in Major Depressive Disorder During Post-COVID Syndrome (Journal of Clincial Psychiatrist) Reaching out to US house representative
Letters read on TWiV 1220
Dr. Griffin’s COVID treatment summary (pdf)
Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1219: Koalas sweep horse shift May 18, 2025

TWiV reviews pause in the use of Chikungunya vaccine, HHS to stop recommending COVID shots for pregnant women and children, molecular basis for shifted receptor recognition by an encephalitic alphavirus, and evolution of koala retrovirus transcriptional silencing in wild koalas.

Hosts: Vincent Racaniello, and Rich Condit

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

Links for this episode

Support science education at MicrobeTV
Pause in use of Ixchiq (FDA)
Change in COVID vaccine recommendations (STAT)
Basis for receptor shift in encephalitic alphavirus (Cell)
Transcriptional silencing of koala retrovirus (Cell)
Letters read on TWiV 1219
Timestamps by Jolene Ramsey. Thanks!

Weekly Picks

Rich – What’s that stuff in your bellybutton? Science has the answer. Vincent – New study reveals our skin’s own bacteria can help protect us from the bad effects of sunlight

Listener Pick

Rona – My Italian secret: the forgotten heroes and Italy and the Holocaust Foundation, Inc.

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1218: Clinical update with Dr. Daniel Griffin May 17, 2025

In his weekly clinical update, Dr. Griffin with Vincent Racaniello wail about the attack on science within the US, cancellation of CDC’s committee on infectious diseases, mpox in Sierra Leone, “bird flu” in cats, the ongoing measles outbreak globally, before Dr. Griffin reviews recent statistics on RSV, benefits of vaccination for infants, influenza and SARS-CoV-2 infections the WasterwaterScan dashboard, the high number of childhood deaths during this “flu” season, the May 22 VRBPAC COVID-19 vaccine meeting, where to find PEMGARDA, benefit of remedesivir, provides information for Columbia University Irving Medical Center’s long COVID treatment center, where to go for answers to your long COVID questions, weight and distinct symptoms of long COVID and contacting your federal government representative to stop the assault on science and biomedical research.

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

Links for this episode

Shut down federal advisory committee on infection prevention…..Make America Healthy Again! (CIDRAP)
Mpox in Sierra Leone (CIDRAP)
H5 Bird Flu: Current Situation (CDC: Avian Influenza (Bird Flu) )
Spike in avian flu cases in cats : spillover into humans? (CIDRAP)
Measles cases and outbreaks (CDC Rubeola)
Measles 800 in Texas…. (Texas Health and Human Services)
Measles outbreak in North Dakota prompts local health officials to quarantine unvaccinated schoolchildren (CNN)
2025 Measles outbreak guidance (New Mexico Health)
Measles and rubella weekly monitoring report: (Government of Canada)
The Mennonites in a Texas community where measles is spreading (AP News)
Trust the government? Seriously! West Texans, Mennonites at center of measles outbreak choose medical freedom over vaccine mandates (AP News)
Measles vaccine recommendations from NYP (jpg)
Deporting Measles! (AP News)
Get the FACTS about measles (NY State Department of Health)
Measles (CDC Measles (Rubeola))
Measles vaccine (CDC Measles (Rubeola))
Presumptive evidence of measles immunity (CDC)
Contraindications and precautions to measles vaccination (CDC)
Measles (CDC Measles (Rubeola))
Measles (CDC: Measles Rubeola)
Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America)
Deaths following vaccination: what does the evidence show (Vaccine)
Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
US respiratory virus activity (CDC Respiratory Illnesses)
Weekly surveillance report: clift notes (CDC FluView)
Respiratory virus activity levels (CDC Respiratory Illnesses)
CDC reports 216 child deaths this flu season (AP News)
Weekly surveillance report: clift notes (CDC FluView)
New York sees highest flu-related pediatric deaths ever recorded in a season (Times Union)
Phase 3 Safety and Efficacy Study of Baloxavir Marboxil in Children Less Than 1 Year Old With Suspected or Confirmed Influenza (The Pediatric Infectious Disease Journal)
FDA-CDC-DOD: 2025-2046 influenza vaccine composition (FDA)
RSV: Waste water scan for 11 pathogens (WastewaterSCan)
US respiratory virus activity (CDC Respiratory Illnesses)
RSV-Network (CDC Respiratory Syncytial virus Infection)
Interim Evaluation of Respiratory Syncytial Virus Hospitalization Rates Among Infants and Young Children After Introduction of Respiratory Syncytial Virus Prevention Products (CDC: MMWR)
US infant mortality dropped in 2024: RSV vaccine? (AP News)
Infant Mortality Dashboard (CDC: National Center for Health Statistics)
Waste water scan for 11 pathogens (WastewaterSCan)
COVID-19 deaths (CDC)
COVID-19 national and regional trends (CDC)
Wastewater Measures of SARS-CoV-2 Accurately Predict Frequency of Symptomatic Infections in the Community (JID)
Origin of SARS-CoV-2
The recency and geographical origins of the bat viruses ancestral to SARS-CoV and SARS-CoV-2 (Cell)
COVID-19 variant tracker (CDC)
SARS-CoV-2 genomes galore (Nextstrain)
COVID-19 infection history as a risk factor for early pregnancy loss (BMC Medicine)
New recommendations seek treatments for post-Lyme disease condition (CIDRAP)
Immunogenicity and Safety of Influenza and COVID-19 Multicomponent Vaccine in Adults ≥50 YearsA Randomized Clinical Trial (JAMA)
Combo flu-COVID vaccine shows good immune response, safety in older adults (CIDRAP)
US FDA advisers to discuss COVID-19 vaccine recommendations on May 22 (Reuters)
Interim Clinical Considerations for Use of COVID-19 Vaccines in the United States (CDC: COVID-19)
COVID-19 vaccine VRBPAC May 22 (FDA)
Where to get pemgarda (Pemgarda)
EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
Infusion center (Prime Fusions)
CDC Quarantine guidelines (CDC)
NIH COVID-19 treatment guidelines (NIH)
Drug interaction checker (University of Liverpool)
Infectious Disease Society guidelines for treatment and management (ID Society)
Molnupiravir safety and efficacy (JMV)
Convalescent plasma recommendation for immunocompromised (ID Society)
What to do when sick with a respiratory virus (CDC)
When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)
Managing healthcare staffing shortages (CDC)
Steroids,dexamethasone at the right time (OFID)
Anticoagulation guidelines (hematology.org)
Remdesivir associated with reduced mortality in hospitalized COVID-19 patients (BMC Infectious Diseases)
Real-world evidence shows remdesivir tied to less death in hospitalized COVID patients (CIDRAP)
Daniel Griffin’s evidence based medical practices for long COVID (OFID)
Long COVID hotline (Columbia : Columbia University Irving Medical Center)
The answers: Long COVID
Excess weight is associated withneurological and neuropsychiatric symptoms in post-COVID-19 condition (PLoS One)
Identification of soluble biomarkers that associate with distinct manifestations of long COVID (Nature Immunology)
Reaching out to US house representative
Letters read on TWiV 1218
Dr. Griffin’s COVID treatment summary (pdf)
Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1217: Alternative vax and pandemic origins May 11, 2025

TWiV reviews new CBER chief at FDA, ending of Gates Foundation in 2045, gain of function executive order, origins of bat viruses ancestral to SARS-CoV and SARS-CoV-2, and single dose Sudan virus replicon vaccine protects guinea pigs from disease.

Hosts: Vincent Racaniello, Alan Dove, and Rich Condit

Subscribe (free): Apple Podcasts, RSS, email

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Links for this episode

Support science education at MicrobeTV
Prasad replaces Marks at FDA (US News)
Gates Foundation ends 2025 (Gates Foundation)
Gain of function Executive Order (White House)
DURC policy (HHS)
Origins of bat viruses ancestral to SARS-CoV and SARS-CoV-2 (Cell)
Sudan virus replicon vaccine (Nat Comm)
Letters read on TWiV 1217
Timestamps by Jolene Ramsey. Thanks!

Weekly Picks

Rich – Andor Season 2 Alan – Sequencing Mendel’s pea plant traits, and a good Science news article on the work Vincent – 2023 summer warmth unparalleled over the past 2,000 years

Listener Pick

Brian – Virology Capabilities Test (VCT): A Multimodal Virology Q&A Benchmark

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1216: Clinical update with Dr. Daniel Griffin May 10, 2025

In his weekly clinical update, Dr. Griffin with Vincent Racaniello bemoan the attack on science within the US, salt water controls for vaccines, return to 1938 technology for flu vaccines, mRNA vaccines as “bioweapons”, rise in pertussis, benefits of the shingles vaccine and reduced dementia occurrence, and growing measles outbreak globally before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, the May 22 VRBPAC COVID-19 vaccine, meeting, where to find PEMGARDA, return to antibiotic treatment for respiratory viral diseases, provides information for Columbia University Irving Medical Center’s long COVID treatment center, where to go for answers to your long COVID questions and contacting your federal government representative to stop the assault on science and biomedical research.

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

Links for this episode

Saline placebo control testing for new vaccines….not good chemistry! (Washington Post)
1940s innovation: HHS, NIH Launch Next-Generation Universal Vaccine Platform for Pandemic-Prone Viruses(US Department of Health and Human Services)
WHAT! Minnesota Bill Against Vaccines Promotes Disinformation (Medscape Medical News) )
Guns= fine….mRNA =mRNA Bioweapons Prohibition Act; mRNA injections and products designated as weapons of mass destruction, and mRNA injections and products prohibited. (Minnesota Legislature)
Bioweapons of massive destruction mNRA not bombs or drones….but mRNA! (Minnesota Legislature)
2024 Provisional pertussis surveillance report (CDC)
Pertussis cases by year 1922-2023 (CDC: Whooping cough (pertussis))
Deaths by pertussis: 6 children under a year old (CDC)
Pertussis (WHO)
Symptoms of pertussis (CDC Whooping Cough (Pertussis)
With whooping cough cases on the rise, a doctor explains how to protect yourself and others (CNN)
Live zoster vaccination and cardiovascular outcomes (European Heath Journal)
Shingles vaccine recipients see lower cardiac event risk (CIDRAP)
H5 Bird Flu: Current Situation (CDC: Avian Influenza Bird flu)
Measles cases and outbreaks (CDC Rubeola)
Measles 800 in Texas…. (Texas Health and Human Services)
2025 Measles outbreak guidance (New Mexico Health)
Measles and rubella weekly monitoring report: (Government of Canada)
Measles vaccine recommendations from NYP (jpg)
Get the FACTS about measles (NY State Department of Health)
Measles (CDC Measles (Rubeola))
Measles vaccine (CDC Measles (Rubeola))
Presumptive evidence of measles immunity (CDC)
Contraindications and precautions to measles vaccination (CDC)
Measles (CDC Measles (Rubeola))
Measles (CDC: Measles Rubeola)
Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America)
Deaths following vaccination: what does the evidence show (Vaccine)
Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
US respiratory virus activity (CDC Respiratory Illnesses)
Weekly surveillance report: clift notes (CDC FluView)
Respiratory virus activity levels (CDC Respiratory Illnesses)
CDC reports 216 child deaths this flu season (AP News)
Weekly surveillance report: clift notes (CDC FluView)
FDA-CDC-DOD: 2025-2046 influenza vaccine composition (FDA)
RSV: Waste water scan for 11 pathogens (WastewaterSCan)
US respiratory virus activity (CDC Respiratory Illnesses)
RSV-Network (CDC Respiratory Syncytial virus Infection)
Impact of Nirsevimab on RSV and Non-RSV Severe Respiratory Infections in Hospitalized Infants (Influenza and other respiratory viruses)
Hospital admissions of respiratory infections in infants plunge with nirsevimab RSV antibody(CIDRAP)
Waste water scan for 11 pathogens (WastewaterSCan)
COVID-19 deaths (CDC)
COVID-19 national and regional trends (CDC)
COVID-19 variant tracker (CDC)
SARS-CoV-2 genomes galore (Nextstrain)
Early effectiveness of the BNT162b2 KP.2 vaccine against COVID-19 in the US Veterans Affairs Healthcare System (Nature Commications)
Interim Clinical Considerations for Use of COVID-19 Vaccines in the United States (CDC: COVID-19)
COVID-19 vaccine VRBPAC May 22 (FDA)
Where to get pemgarda (Pemgarda)
EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
Infusion center (Prime Fusions)
CDC Quarantine guidelines (CDC)
NIH COVID-19 treatment guidelines (NIH)
Drug interaction checker (University of Liverpool)
Infectious Disease Society guidelines for treatment and management (ID Society)
Time to antiviral treatment in mild–moderate COVID-19 in the emergency department(Internal and Emergency Medicine)
Delays in COVID antiviral receipt raised risk of poor outcomes after ED visits by 18%, data suggest(CIDRAP)
Molnupiravir safety and efficacy (JMV)
Convalescent plasma recommendation for immunocompromised (ID Society)
What to do when sick with a respiratory virus (CDC)
When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)
Managing healthcare staffing shortages (CDC)
Virus = Bacteria ? National Trends in Antibiotic Prescribing for Adults Hospitalized With Coronavirus Disease 2019 and Other Viral Respiratory Infections (OFID)
Steroids, dexamethasone at the right time (OFD)
Anticoagulation guidelines (hematology.org)
Daniel Griffin’s evidence based medical practices for long COVID (OFID)
Long COVID hotline (Columbia : Columbia University Irving Medical Center)
The answers: Long COVID
Short and long-term trajectories of the post COVID-19 condition (BMJ Infectious Diseases)
Prevalence of Persistent Cardiovascular and Pulmonary Abnormalities on PET/MRI and DECT Imaging in Long COVID Patients (Journal of Nuclear Medicine)
Long-COVID patients show signs of inflammation on PET/ MRI scans(CIDRAP)
Reaching out to US house representative
Letters read on TWiV 1216
Dr. Griffin’s COVID treatment summary (pdf)
Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV Special: A shot of HepB with Thomas Tu May 06, 2025

From the 2024 International Hepatitis B virus meeting in Chicago IL, Rich Condit speaks with Thomas Tu about his experiences as a both a HepB scientist and patient.

Host: Rich Condit

Guest: Thomas Tu

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

Links for this episode

Support science education at MicrobeTV
Hepatitis B Foundation
Tu Laboratory
Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1215: What's the worst that could happen? May 04, 2025

TWiV reviews universal vaccine initiative at NIAID, shut down of the Integrated Research Facility at Ft. Detrick, modeling the reemergence of infectious diseases as vaccination rates drop, and bacterial outer membrane vesicles bound to bacteriophages modulate neutrophil responses to bacterial infection.

Hosts: Vincent Racaniello, Alan Dove, and Jolene Ramsey

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

Links for this episode

Support science education at MicrobeTV
ASV 2025
Paul has Measles (YouTube, virology blog)
Universal vaccine project (NIAID, CIDRAP)
Measles update (US, Texas)
Integrated Research Lab closed (Telegraph)
Modeling reemergence of infectious diseases (JAMA)
Outer membrane vesicles attached to phage (Front Cell Inf Micro)
Pf phage review (Front Immunol)
Letters read on TWiV 1215
Timestamps by Jolene Ramsey. Thanks!

Weekly Picks

Alan – A Paradise Built in Hell, by Rebecca Solnit (and here’s my review of it) Jolene – Virology course student communication projects, Spring 2025 Vincent – Vaccine Education Center

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1214: Clinical update with Dr. Daniel Griffin May 03, 2025

In his weekly clinical update, Dr. Griffin with Vincent Racaniello bewail the attack on science within the US and withdrawal from the global health communities, association between the shingles vaccine and reduced dementia occurrence, ending of Uganda’s ebola outbreak, undermining effective responses to human bird flu infections, growing measles outbreak in the US and dire predictions of the return of vaccine preventable diseases including polio if vaccination rates continue to decline, before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections the WasterwaterScan dashboard, how HHS is undermining the Novavax COVID-19 vaccine, if Paxlovid reduces stroke, where to find PEMGARDA, provides information for Columbia University Irving Medical Center’s long COVID treatment center, where to go for answers to your long COVID questions and contacting your federal government representative to stop the assault on science and biomedical research.

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

Links for this episode

Lab animal RIFFing (NY Times)
Herpes zoster vaccination and dementia occurrence(JAMA)
The recombinant shingles vaccine is associated with lower risk of dementia (Nature Medicine)
Uganda declares end to latest ebola outbreak (Reuters)
Enhancing the response to avian influenza in the US and globally (LANCET: Regional Health-Americas)
H5 Bird Flu: Current Situation (CDC: Avian Influenza Bird flu)
Measles Update — United States, January 1–April 17, 2025 (CDC: MMWR)
Measles in Europe……..but greater in the US (CIDRAP)
Measles – Annual Epidemiological Report for 2024 (ECDC: European Center for Disease Prevention and Control)
Measles (ECDC: European Center for Disease Prevention and Control)
Measles cases and outbreaks (CDC Rubeola)
Measles 800 in Texas…. (Texas Health and Human Services)
2025 Measles outbreak guidance (New Mexico Health)
On the precipice of disaster’: Measles may be endemic in 25 years if vaccine uptake stays low, model predicts (CIDRAP)
Modeling Reemergence of Vaccine-Eliminated Infectious Diseases Under Declining Vaccination in the US (JAMA)
Measles vaccine recommendations from NYP (jpg)
Get the FACTS about measles (NY State Department of Health)
Measles (CDC Measles (Rubeola))
Measles vaccine (CDC Measles (Rubeola))
Presumptive evidence of measles immunity (CDC)
Contraindications and precautions to measles vaccination (CDC)
Measles (CDC Measles (Rubeola))
Measles (CDC: Measles Rubeola)
Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
Measles Vaccination: Know the Facts(ISDA: Infectious Diseases Society of America)
Deaths following vaccination: what does the evidence show (Vaccine)
Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
US respiratory virus activity (CDC Respiratory Illnesses)
Weekly surveillance report: clift notes (CDC FluView)
Respiratory virus activity levels (CDC Respiratory Illnesses)
200 children die from flu (CIDRAP)
Weekly surveillance report: clift notes (CDC FluView)
FDA-CDC-DOD: 2025-2046 influenza vaccine composition (FDA)
RSV: Waste water scan for 11 pathogens (WastewaterSCan)
US respiratory virus activity (CDC Respiratory Illnesses)
RSV-Network (CDC Respiratory Syncytial virus Infection)
Waste water scan for 11 pathogens (WastewaterSCan)
COVID-19 deaths (CDC)
COVID-19 national and regional trends (CDC)
COVID-19 variant tracker (CDC)
SARS-CoV-2 genomes galore (Nextstrain)
Health secretary RFK Jr. declares certain vaccines have ‘never worked,’ flummoxing scientists…..what certain vaccines?(STAT News)
More FDA uncertainty roils full approval for Novavax COVID vaccine (CIDRAP)
FDA Punts on Major Covid-19 Vaccine Decision After Ouster of Top Official (WSJ)
U.S. health officials inject new uncertainty into approval process for Covid boosters (STAT News)
Interim Clinical Considerations for Use of COVID-19 Vaccines in the United States (CDC: COVID-19)
Where to get pemgarda (Pemgarda)
EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
Infusion center (Prime Fusions)
CDC Quarantine guidelines (CDC)
NIH COVID-19 treatment guidelines (NIH)
Drug interaction checker (University of Liverpool)
Infectious Disease Society guidelines for treatment and management (ID Society)
Molnupiravir safety and efficacy (JMV)
Convalescent plasma recommendation for immunocompromised (ID Society
What to do when sick with a respiratory virus (CDC)
When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)
Managing healthcare staffing shortages (CDC)
Steroids, dexamethasone at the right time (OFID)
Anticoagulation guidelines (hematology.org)
Into the Unknown: Practical Remdesivir Restriction in the Era of Widespread SARS-CoV-2 Seropositivity (CID)
Tocilizumab and IVIG experience during the service follow-up in patients with severe COVID-19 pneumonia(Rev Insti MedTrop Sao Paulo)
Daniel Griffin’s evidence based medical practices for long COVID (OFID)
Long COVID hotline (Columbia : Columbia University Irving Medical Center)
The answers: Long COVID
Risk of New-Onset Type 2 Diabetes Among Vaccinated Adults After Omicron or Delta Variant SARS-CoV-2 Infection(JAMA) Reaching out to US house representative
Letters read on TWiV 1214
Dr. Griffin’s COVID treatment summary (pdf)
Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV Special: A shot of HepB with Chari Cohen Apr 29, 2025

From the 2024 International Hepatitis B virus meeting in Chicago IL, Rich Condit speaks with Chari Cohen about her work as President of the Hepatitis B Foundation.

Host: Rich Condit

Guest: Chari Cohen

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

Links for this episode

Support science education at MicrobeTV
Hepatitis B Foundation
Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1213: Secrets of HepB cccDNA Apr 27, 2025

TWiV reviews new committee of experts to counter vaccine misinformation, resignation of NSF Director, dependence of immune response to rabies virus on the gut microbiome, and a nucleosome switch primes hepatitis B virus infection.

Hosts: Vincent Racaniello, Rich Condit, and Angela Mingarelli

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

Links for this episode

Support science education at MicrobeTV
ASV 2025
Committee of experts to counter vaccine misinformation (Science)
NSF Director resigns (Science)
Dependence of vaccine immune response on gut microbiome (Cell Host Microbe)
Nucleosome switch primes HepB replication (Cell)
Letters read on TWiV 1212
Timestamps by Jolene Ramsey. Thanks!

Weekly Picks

Angela – Wild chimpanzees filmed by scientists bonding over alcoholic fruit Rich – Malcolm Gladwell Revisionist History “The Joe Rogan Intervention” Vincent – Measles Misinformation Is on the Rise — and Americans Are Hearing It, Survey Finds

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1212: Clinical update with Dr. Daniel Griffin Apr 26, 2025

In his weekly clinical update, Dr. Griffin with Vincent Racaniello deplore the US’s withdrawal from the global health community for pandemic preparedness i.e. the universal avian flu vaccine, and undermining the use of routine childhood vaccinations for pertussis and measles, RFK’s autism registry, yellow fever outbreak in Colombia and world immunization week after discussing the squirrel as the reservoir host for mpox, before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections the WasterwaterScan dashboard, how immunity elicited by the RSV vaccine wanes in 3 years, if Paxlovid reduces stroke, where to find PEMGARDA, provides information for Columbia University Irving Medical Center’s long COVID treatment center, where to go for answers to your long COVID questions, if vaccination impacts long COVID and if long COVID were to become epidemic.

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

Links for this episode

The American Public’s Disengagement With Highly Pathogenic Avian Influenza (HPAI): Considerations for Vaccination and Dietary Changes(American Public Health Association)
New agreement geared toward universal avian flu vaccine (CIDRAP)
Cambridge’s DIOSynVax and Singapore’s ACM Biolabs to advance pandemic-ready universal bird flu vaccine with international support (GlobeNewswire)
Bird flu continues to spread among live poultry markets after shut down order (CRAIN’S New York Business)
Fire-footed rope squirrels (Funisciurus pyrropus) are a reservoir host of monkeypox virus (Orthopoxvirus monkeypox)(Research Square)
It is a squirrel! An animal source of mpox emerges(Nature)
Whooping cough spikes, especially among unvaccinated teens (NBC News)
A February flu surge has arrived (NCB News)
Pertussis Cases by Year (1922-2022)(CDC: Whooping cough (pertussis)))
‘Fighting to breathe’: Whooping cough surges as vaccination rate falters (NBC News)
CDC cancels measles help for Texas schools amid staff layoffs (HealthDay)
Measles cases and outbreaks (CDC Rubeola)
Measles in Texas…. (Texas Health and Human Services)
Measles vaccine recommendations from NYP (jpg)
2025 Measles outbreak guidance (New Mexico Health)
Get the FACTS about measles (NY State Department of Health)
Measles (CDC Measles (Rubeola))
Measles vaccine (CDC Measles (Rubeola))
Presumptive evidence of measles immunity (CDC)
Contraindications and precautions to measles vaccination (CDC)
Measles (CDC Measles (Rubeola))
Measles (CDC: Measles Rubeola)
Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
Measles Vaccination: Know the Facts(ISDA: Infectious Diseases Society of America)
Deaths following vaccination: what does the evidence show (Vaccine)
RFK Jr.’s autism registry plan (Axios)
RFK Jr’s autism study collecting Americans’ private medical records (Guardian)
The public’s views on measles outbreaks and misinformation (KFF)
Colombia National Emergency: yellow fever cases (Gov.Co)
World Immunization Week: polio eradiation?(GPEI)
Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
US respiratory virus activity (CDC Respiratory Illnesses)
Weekly surveillance report: clift notes (CDC FluView)
Respiratory virus activity levels (CDC Respiratory Illnesses)
200 children die from flu (CIDRAP)
Weekly surveillance report: clift notes (CDC FluView)
FDA-CDC-DOD: 2025-2046 influenza vaccine composition (FDA)
RSV: Waste water scan for 11 pathogens (WastewaterSCan)
US respiratory virus activity (CDC Respiratory Illnesses)
RSV-Network (CDC Respiratory Syncytial virus Infection)
Trial shows waning efficacy of RSV vaccine across 3 seasons in older adults(CIDRAP)
Efficacy, safety, and immunogenicity of the AS01E-adjuvanted respiratory syncytial virus prefusion F protein vaccine (RSVPreF3 OA) (LANCET: Respiratory Medicine)
Waste water scan for 11 pathogens (WastewaterSCan)
COVID-19 deaths (CDC)
COVID-19 national and regional trends (CDC)
COVID-19 variant tracker (CDC)
SARS-CoV-2 genomes galore (Nextstrain)
Where to get pemgarda (Pemgarda)
EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
Infusion center (Prime Fusions)
CDC Quarantine guidelines (CDC)
NIH COVID-19 treatment guidelines (NIH)
Drug interaction checker (University of Liverpool)
Long-term stroke and mortality risk reduction associated with acute-phase paxlovid use in mild-to-moderate COVID-19(Journal of Medical Virology)
Infectious Disease Society guidelines for treatment and management (ID Society)
Molnupiravir safety and efficacy (JMV)
Convalescent plasma recommendation for immunocompromised (ID Society)
What to do when sick with a respiratory virus (CDC)
When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)
Managing healthcare staffing shortages (CDC)
Steroids, dexamethasone at the right time (OFID)
Anticoagulation guidelines (hematology.org)
Daniel Griffin’s evidence based medical practices for long COVID (OFID)
Long COVID hotline (Columbia : Columbia University Irving Medical Center)
The answers: Long COVID
The effect of COVID-19 vaccination on the risk of persistent post–COVID-19 condition (JID)
ORCHESTRA Delphi consensus: diagnostic and therapeutic management of Post-COVID-19 condition in vulnerable populations (CMI Clinical Microbiology and Infection)
Political ideology and trust in scientists in the USA(Nature Human Behavior)
Leading long COVID researcher fears it could become a national epidemic (Spectrum News NY1)
Center for post COVID care (Mt. Sinai) Reaching out to US house representative
Letters read on TWiV 1212
Dr. Griffin’s COVID treatment summary (pdf)
Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV Special: A shot of HepB with Stephan Urban Apr 22, 2025

From the 2024 International Hepatitis B virus meeting in Chicago IL, Rich Condit speaks with Stephan Urban about his career working on HBV and HDV, and his philanthropy.

Host: Rich Condit

Guest: Stephan Urban

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

Links for this episode

Support science education at MicrobeTV
ASV 2025
Hepatitis delta: recent advances (Hepatology)
Bulevirtide for HBV and HDV (Lancet Inf Dis)
Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1211: Moo flu and dengue two Apr 20, 2025

TWiV discusses the rising autism rate among children, RFK Jr.’s claim that autism ‘destroys lives’, receptor binding specificity of a bovine H5N1 influenza virus, and improved dengue subunit vaccine modified to form E protein dimers.

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Brianne Barker

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

Links for this episode

Support science education at MicrobeTV
ASV 2025
Rising autism rate among children (MMWR)
RFK Jr. claims autism ‘destroys lives‘ (NY Times)
Receptor binding specificity of bovine H5N1 virus (Nature)
Bovine H5N1 binds poorly to human receptors (Nature)
AJ Eisfeld et al reply (Nature)
Mootant influenza H5N1 virus (TWiV 1131)
Improved dengue 2 subunit vaccine (J Virol)
Letters read on TWiV 1211
Timestamps by Jolene Ramsey. Thanks!

Weekly Picks

Brianne – Scientists detect signature of life on a distant planet, study suggests Rich – Hanlon’s Razor Alan – Baby colossal squid filmed in deep ocean Vincent – How the United States became a science superpower — and how quickly it could crumble

Listener Pick

John – Revisionist History: The RFK Jr. Problem

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1210: Clinical update with Dr. Daniel Griffin Apr 19, 2025

In his weekly clinical update, Dr. Griffin with Vincent Racaniello rue about the continuation of the gutting of the American public health infrastructure, the continuing measles outbreak, an unreported outbreak of deadly E.coli human infections, meningococcal disease before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, ACIP recommended changes in guidelines for the RSV and COVID-19 vaccines, reactogenicity differences between Novavax and Pfizer COVID-19 vaccines, where to find PEMGARDA, provides information for Columbia University Irving Medical Center’s long COVID treatment center, where to go for answers to your long COVID questions, long COVID interventions, effects of long COVID in children and adolescents and a list of ongoing clinical trials for long COVID treatment.

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

Links for this episode

Making America Healthy Again-purging of administrators at HHS (Politico)
Making America Healthy Again-purging of data (Politico)
Deep cuts of the federal government (NY Times)
Cutting NIH, CDC and HHS promotes chronic disease research(Washington Post)
Political ideology and trust in scientists in the USA(Nature Human Behavior)
US political conservatives have deep, unbudging suspicion of science, survey suggests(CIDRAP)
A deadly E. coli outbreak hit 15 states, but the FDA chose not to publicize it(NBC News)
Invasive meningococcal disease – Kingdom of Saudi Arabia(WHO)
The essential guide to understanding the differences between hajj and umrah (Marhabahaji)
Measles Vaccination: Know the Facts(ISDA: Infectious Diseases Society of America)
Measles booster? (Washington Post)
How to stop an outbreak…….fire the experts (Washington Post)
Measles cases and outbreaks (CDC Rubeola)
Measles 159 in Texas…. (Texas Health and Human Services)
2025 Measles outbreak guidance (New Mexico Health)
Measles and rubella weekly monitoring (Government of Canada)
Measles vaccine recommendations from NYP (jpg)
NAFMA: North American Free Measles agreement…..(NY Times)
Get the FACTS about measles (NY State Department of Health)
Measles (CDC Measles (Rubeola))
Measles vaccine (CDC Measles (Rubeola))
Presumptive evidence of measles immunity (CDC)
Contraindications and precautions to measles vaccination (CDC)
Measles (CDC Measles (Rubeola))
Doctors’ talk measles (YouTube)
Measles (CDC: Measles Rubeola)
Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
Measles Vaccination: Know the Facts(ISDA: Infectious Diseases Society of America)
Deaths following vaccination: what does the evidence show (Vaccine)
Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
US respiratory virus activity (CDC Respiratory Illnesses)
Weekly surveillance report: clift notes (CDC FluView)
Respiratory virus activity levels (CDC Respiratory Illnesses)
200 children die from flu (CIDRAP)
Weekly surveillance report: clift notes (CDC FluView)
FDA-CDC-DOD: 2025-2046 influenza vaccine composition (FDA)
RSV: Waste water scan for 11 pathogens (WastewaterSCan)
US respiratory virus activity (CDC Respiratory Illnesses)
RSV-Network (CDC Respiratory Syncytial virus Infection)
ACIP votes to expand recommendation for Pfizer’sRSV vaccine Abrysvo® to include adults aged 50 to 59 at increased risk of disease (Pfizer)
Respiratory syncytial virus and incidence of cardiovascular events: a nationwide self-controlled case series analysis (JACC Journals)
Waste water scan for 11 pathogens (WastewaterSCan)
COVID-19 deaths (CDC)
COVID-19 national and regional trends (CDC)
COVID-19 variant tracker (CDC)
SARS-CoV-2 genomes galore (Nextstrain)
Comorbidities associated with different degrees of severity in children and young people hospitalized with acute COVID-19 (Pediatric Infectious Disease Journal)
SHIELD-Utah study shows Novavax’s COVID-19 vaccine induces lower reactogenicity symptoms compared to mRNA (Novavax)
Interim clinical considerations for use of COVID-19 vaccines in the United States (CDC Vaccines & Immunizations)
Novavax says its COVID vaccine produces fewer, milder reactions than Pfizer version(CIDRAP)
US CDC advisers discuss narrower use of COVID-19 vaccines (Reuters)
Where to get pemgarda (Pemgarda)
EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
Infusions center (Prime Fusions)
CDC Quarantine guidelines (CDC)
NIH COVID-19 treatment guidelines (NIH)
Drug interaction checker (University of Liverpool)
Infectious Disease Society guidelines for treatment and management (ID Society)
Molnupiravir safety and efficacy (JMV)
Convalescent plasma recommendation for immunocompromised (ID Society)
What to do when sick with a respiratory virus (CDC)
When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)
Managing healthcare staffing shortages (CDC)
Steroids, dexamethasone at the right time (OFID)
Anticoagulation guidelines (hematology.org)
Daniel Griffin’s evidence based medical practices for long COVID (OFID)
Long COVID hotline (Columbia : Columbia University Irving Medical Center)
The answers: Long COVID
Kidney Function following COVID-19 in children and adolescents(JAMA Network Open)
Cardiovascular post-acute sequelae of SARS-CoV-2 in children and adolescents: cohort study using electronic health records(Nature Communications)
Great barrington declaration (gbdeclaration.org)
Clinical trials:
Effectiveness of transcranial direct current in patients with persistent COVID-19 with headaches and chronic pain.
Home-based Brain Stimulation Treatment for Post-acute Sequelae of COVID-19 (PASC)
Acupuncture for post COVID-19 Condition (Long COVID) neuropsychiatric symptoms
Pain relief with integrative medicine (prime)?: feasibility of acupuncture for long COVID
Electro-acupuncture for long COVID neuropsychiatric symptoms
Randomised study to investigate the effectiveness of acupuncture for the relief of long COIVD-19 related fatigue (ACU-COVID)
Vagus stimulation in female long COVID patients.(Vagus)
Stellate ganglion block with lidocaine for the treatment of COVID-19-induced parosmia (Stella)
Therapeutic updates on long COVID: Where things stand 5 years later (ID Society)
Reaching out to US house representative
Letters read on TWiV 1210
Dr. Griffin’s COVID treatment summary (pdf)
Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1209: Just say no to norovirus Apr 13, 2025

TWiV reviews RFK Jr’s odd comments on ‘single antigen’ vaccines and his September deadline for understanding why autism has increased, dire wolf does not come back from the dead, oral norovirus vaccine tablet that induces mucosal immunity in older adults, and identification of broadly neutralizing human monoclonal antibodies against norovirus.

Hosts: Vincent Racaniello, Alan Dove, Kathy Spindler, and Brianne Barker

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

Links for this episode

Support science education at MicrobeTV
ASV 2025
RFK Jr. and Novavax (MSN)
September deadline to understand autism rise (Reuters)
Dire wolf not resurrected (Science)
Oral norovirus vaccine tablet (Sci Transl Med)
Broadly neutralizing norovirus monoclonal antibodies (Sci Transl Med)
Letters read on TWiV 1209
Timestamps by Jolene Ramsey. Thanks!

Weekly Picks

Brianne – New experiment updates classic experiment on how life on Earth started Kathy – APOD ISS meets Venus, Sign up for NASA ISS alerts, GoISS Watch Alan – Mason bees could replace honeybees as crop pollinators Vincent – Mystery of medieval manuscripts revealed by ancient DNA

Listener Pick

Sonrisa – GOT’EM Good!

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1208: Clinical update with Dr. Daniel Griffin Apr 12, 2025

In his weekly clinical update, Dr. Griffin with Vincent Racaniello mourn the demise of vaccination against childhood diseases when discussing the continuing measles outbreak and the rise of pertussis, the first human case of H5N1 in Mexico, and human metapneumovirus before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections and vaccination schedules, the WasterwaterScan dashboard, where to find PEMGARDA, provides information for Columbia University Irving Medical Center’s long COVID treatment center, where to go for answers to your long COVID questions, long COVID interventions, if antiviral therapy prevents long COVID and how long COVID may affect brain volume.

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

Links for this episode

A natural experiment on the effect of herpes zoster vaccination on dementia (Nature)
Taking a shot at dementia (microbeTV: TWiV)
RFK Jr. visits Texas after second child dies of measles amid outbreak (Washington Post)
Kennedy Attends Funeral of Texas Girl Who Died of Measles(NY Times)
‘Most effective way’ to prevent measles is vaccination, RFK Jr. says, in most direct remarks yet (STAT News)
Fort Bliss…..Fort measles: Beaumont Army hospital confirms measles case at Fort Bliss(KTSM News)
Measles cases and outbreaks (CDC Rubeola)
Measles 159 in Texas…. (Texas Health and Human Services)
Measles vaccine recommendations from NYP (jpg)
2025 Measles outbreak guidance (New Mexico Health)
Get the FACTS about measles (NY State Department of Health)
Measles (CDC Measles (Rubeola))
Measles vaccine (CDC Measles (Rubeola)
Presumptive evidence of measles immunity (CDC)
Contraindications and precautions to measles vaccination (CDC)
Measles (CDC Measles (Rubeola))
Doctors’ talk measles (YouTube)
Measles (CDC: Measles Rubeola)
Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
Measles Vaccination: Know the Facts(ISDA: Infectious Diseases Society of America)
Deaths following vaccination: what does the evidence show (Vaccine)
Two infants die of whooping cough in Louisiana (CNN)
Clinical features of pertussis (CDC: Whooping cough Pertussis)
Pertussis vaccination recommendations (CDC: Whooping cough Pertussis)
Diphtheria vaccination (CDC: Diphtheria)
Mexico’s first human case of H5N1 (Reuters)
Human metapneumovirus seasonality and co-circulation with respiratory syncytial virus — United States, 2014–2024 (CDC: MMWR)
Influenza: Wastewater scan for 11 pathogens (WastewaterSCan)
US respiratory virus activity (CDC Respiratory Illnesses)
Weekly surveillance report: clift notes (CDC FluView)
Respiratory virus activity levels (CDC Respiratory Illnesses)
FDA-CDC-DOD: 2025-2046 influenza vaccine composition (FDA)
RSV: Waste water scan for 11 pathogens (WastewaterSCan)
US respiratory virus activity (CDC Respiratory Illnesses)
RSV-Network (CDC Respiratory Syncytial virus Infection)
Waste water scan for 11 pathogens (WastewaterSCan)
COVID-19 deaths (CDC)
COVID-19 national and regional trends (CDC)
COVID-19 variant tracker (CDC)
SARS-CoV-2 genomes galore (Nextstrain)
Human source SARS-CoV-2 aerosol transmission to remote sentinel hamsters (OFID)
Interim clinical considerations for use of COVID-19 vaccines in the United States (CDC Vaccines & Immunizations)
Where to get pemgarda (Pemgarda)
EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
Fusion center (Prime Fusions)
CDC Quarantine guidelines (CDC)
NIH COVID-19 treatment guidelines (NIH)
Drug interaction checker (University of Liverpool)
Infectious Disease Society guidelines for treatment and management (ID Society)
Cost-effectiveness analysis of nirmatrelvir/ritonavir for high-risk individuals with COVID-19….does this mean use the big button calculator? (OFID)
Molnupiravir safety and efficacy (JMV)
Convalescent plasma recommendation for immunocompromised (ID Society)
What to do when sick with a respiratory virus (CDC)
When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)
Managing healthcare staffing shortages (CDC)
Steroids, dexamethasone at the right time (OFID)
Anticoagulation guidelines (hematology.org)
Daniel Griffin’s evidence based medical practices for long COVID (OFID)
Long COVID hotline (Columbia : Columbia University Irving Medical Center)
The answers: Long COVID
Nirmatrelvir–ritonavir versus placebo–ritonavir in individuals with long COVID in the USA (PAX LC): (LANCET: Infectious Diseases)
Quantitative brain volume differences between COVID-19 patients and non-COVID-19 volunteers (NeuroImage)
Donepezil for fatigue and psychological symptoms in post–covid-19 condition (JAMA Network Open)
Letters read on TWiV 1208
Dr. Griffin’s COVID treatment summary (pdf)
Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1207: Taking a shot at dementia Apr 06, 2025

TWiV notes the passing of Klaus Conzelmann, then reviews reverse-zoonoses of 2009 H1N1 pandemic influenza A viruses and evolution in United States swine, and reduction in dementia incidence in recipients of Zostavax.

Hosts: Vincent Racaniello, Alan Dove, and Rich Condit

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

Links for this episode

Support science education at MicrobeTV
ASV 2025
Reverse zoonoses of 2009 H1N1 in US swine (PLoS Path)
Zostavax reduces dementia (Nature)
Letters read on TWiV 1207
Timestamps by Jolene Ramsey. Thanks!

Weekly Picks

Rich – Certain Roller Coasters May Help Small Kidney Stones Pass Alan – Analog and Asimov’s science fiction magazines Vincent – Science Under Threat in the United States: How scientists and institutions should respond

Listener Pick

Charles – Why Techdirt Is Now A Democracy Blog (Whether We Like It Or Not)

TWiV 1206: Clinical update with Dr. Daniel Griffin Apr 05, 2025

In his weekly clinical update, Dr. Griffin and Vincent Racaniello lament about the continuing measles outbreak, whether or not the measles outbreak was predicted, the FACTS about vaccination, high pathogenic influenza, H5N1 contaminated raw pet food, children’s deaths, before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections and vaccination schedules and the efficacy of Moderna’s seasonal mRNA vaccine, societal burden of COVID-19 and influenza, the FDA missed deadline for approving Novovax COVID vaccine, the WasterwaterScan dashboard, where to find PEMGARDA, provides information for Columbia University Irving Medical Center’s long COVID treatment center, where to go for answers to your long COVID questions, long COVID interventions, and Canada’s long COVID dashboard.

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

Links for this episode

CDC buried a measles forecast that stressed the need for vaccinations….TRANSPARENCY? (Politico)
Measles cases and outbreaks (CDC Rubeola)
Measles 159 in Texas…. (Texas Health and Human Services)
2025 Measles outbreak guidance (New Mexico Health)
Measles and rubella weekly monitoring report (Government of Canada)
Enhanced epidemiological summary Measles in Ontario (Public Health Ontario)
Measles and rubella weekly monitoring report (Government of Canada)
Enhanced epidemiological summary Measles in Ontario (Public Health Ontario)
Measles exposures in Ontario (Public Health Ontario)
Measles vaccine recommendations from NYP (jpg)
Get the FACTS about measles (NY State Department of Health)
Measles (CDC Measles (Rubeola))
Measles vaccine (CDC Measles (Rubeola))
Presumptive evidence of measles immunity (CDC)
Contraindications and precautions to measles vaccination (CDC)
Measles (CDC Measles (Rubeola))
Raw cat food tests positive for H5N1 (CIDRAP)
Influenza: Waste water scan for 11 pathogens WastewaterSCan)
US respiratory virus activity (CDC Respiratory Illnesses)
Weekly surveillance report: clift notes (CDC FluView)
Respiratory virus activity levels (CDC Respiratory Illnesses)
FDA-CDC-DOD: 2025-2046 influenza vaccine composition (FDA)
RSV: Waste water scan for 11 pathogens (WastewaterSCan)
US respiratory virus activity (CDC Respiratory Illnesses)
RSV-Network (CDC Respiratory Syncytial virus Infection)
Early impact of RSV vaccination in older adults in England (Lancet)
Waste water scan for 11 pathogens (WastewaterSCan)
COVID-19 deaths (CDC)
COVID-19 national and regional trends (CDC)
COVID-19 variant tracker (CDC)
SARS-CoV-2 genomes galore (Nextstrain)
Evaluating the effectiveness of 2024-2025 seasonal mRNA-1273 vaccination against covid-19-associated hospitalizations and medically attended covid-19 among adults aged ≥ 18 years in the united states(medRxiv)
Current Moderna vaccine 53% effective against COVID hospitalization?(CIDRAP)
Preliminary estimates of COVID-19 burden for 2024-2025 (CDC COVID-19)
Estimated range of annual burden of flu in the US from 2010 – 2024 (CDC-flu burden)
US FDA missed the deadline for decision on Novavax’s COVID-19 vaccine (Reuters)
Interim clinical considerations for use of COVID-19 vaccines in the United States (CDC Vaccines & Immunizations)
Where to get pemgarda (Pemgarda)
EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
Fusion center (Prime Fusions)
CDC Quarantine guidelines (CDC)
NIH COVID-19 treatment guidelines (NIH)
Metformin alleviates inflammatory response and severity rate of COVID-19 infection in elderly individuals(Scientific Reports)
Drug interaction checker (University of Liverpool)
Infectious Disease Society guidelines for treatment and management (ID Society)
Cost-effectiveness analysis of nirmatrelvir/ritonavir for high-risk individuals with COVID-19….does this mean use the big button calculator? (OFID)
Molnupiravir safety and efficacy (JMV)
Convalescent plasma recommendation for immunocompromised (ID Society)
What to do when sick with a respiratory virus (CDC)
When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC
Managing healthcare staffing shortages (CDC)
Steroids, dexamethasone at the right time (OFID)
Anticoagulation guidelines (hematology.org)
Daniel Griffin’s evidence based medical practices for long COVID (OFID)
Long COVID hotline (Columbia : Columbia University Irving Medical Center)
The answers: Long COVID
Reinfection with SARS-CoV-2 in the omicron era is associated with increased risk of post-acute sequelae of SARS-CoV-2 infection: a recover-EHR cohort study(medRxiv)
CAN-PCC RecMap, your one-stop shop for recommendations about Post COVID-19 Condition (Long COVID) (Canadian Guidelines for post COVID-19 condition)
Letters read on TWiV 1206
Dr. Griffin’s COVID treatment summary (pdf)
Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1205: Pluviosity didn't kill the bat Mar 30, 2025

TWiV reviews liver damage caused by over use of vitamin A in Texas, vitamin A does not change clinical course of measles in high income country, NIH cuts COVID-19 research, US ends vaccine funds for poor countries, anti-vaxxer hired to study vaccines and autism, new DURC policy, Jamaican fruit bat competence for filoviruses, and human outbreaks of Oropouche virus reassortant in Brazil.

Hosts: Vincent Racaniello, Alan Dove, Kathy Spindler, and Brianne Barker

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

Links for this episode

Support science education at MicrobeTV
ASV 2025
Vitamin A liver disease in Texas (NY Times)
Vitamin A doesn’t help measles in high-income countries (Pediat Inf Dis)
NIH cancels COVID grants (Science)
US ends vaccine funds for poor countries (NY Times)
Anti-vaxxer to study vaccines and autism (Sci Based Med)
DURC rules revised (USG and NIH guidance)
Filoviruses and Jamaican fruit bats (Nat Comm)
Oropouche outbreaks in Brazil (Nat Med)
Woolly mice (NPR)
Letters read on TWiV 1205
Timestamps by Jolene Ramsey. Thanks!

Weekly Picks

Brianne – Math of March Madness Brackets Kathy – Wood frogsicles #1 and #2 Alan – Rare glimpse of baby polar bears emerging from dens Vincent – Hikaru Utada Would Rather Play CERN Than Coachella

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1204: Clinical update with Dr. Daniel Griffin Mar 29, 2025

In his weekly clinical update, Dr. Griffin with Vincent Racaniello rue about the continuing measles outbreak, the FACTS about vaccination, irresponsibility of promoting vitamin A therapy “lifelong liver damage or vaccinaton!”, high pathogenic influenza and egg importation before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections and vaccination schedules and if vaccination affects long COVID, the WasterwaterScan dashboard, where to find PEMGARDA, provides information for Columbia University Irving Medical Center’s long COVID treatment center, where to go for answers to your long COVID questions, long COVID interventions, how to track long symptoms using a wearable device and how these data will never be used with the closing of governmental long COVID programs and offices.

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

Links for this episode

Measles cases and outbreaks (CDC Rubeola)
Measles 159 in Texas…. (Texas Health and Human Services)
2025 Measles outbreak guidance (New Mexico Health)
10 in Ohio and 23 in Kansas…..oh my! (US News)
Measles data (Kansas: Department of Health and Enivornment)
Health director urges parents to ensure children are vaccinated against measles (Ohio: Department of Health)
Get the FACTS about measles (NY State Department of Health)
New York Governor Kathy Hochul sounds alarm for measles vaccine amid 4 confirmed cases (abc News)
Get the FACTS about measles (NY State Department of Health)
Long-term dynamics of measles virus–specific neutralizing antibodies in children vaccinated before 12 months of age (CID)
Measles vaccine (CDC Measles (Rubeola))
Clinical Overview of Measles (CDC Rubeola)
Red Book: 2024–2027 Report of the Committee on Infectious Diseases (33rd Edition)(Redbook)
Vitamin A in Children Hospitalized for Measles in a High-income Country (Pediatric Infectious Disease Journal)
No vaccination necessary…….instead take vitamin A and develop liver damage….(NY Times)
Measles vaccine recommendations from NYP (jpg)
Measles (CDC Measles (Rubeola))
Measles vaccine (CDC Measles (Rubeola))
Presumptive evidence of measles immunity (CDC)
Contraindications and precautions to measles vaccination (CDC)
Measles (CDC Measles (Rubeola))
Influenza of avian origin confirmed in a sheep in Yorkshire (UK government)
UK reports H5N1 in a sheep on poultry-outbreak farm(CIDRAP)
Don’t send money….send EGGS! (Reuters)
Are your eggs domestic or Brazilian? (Reuters)
USDA to invest 100M in bird flu projects…..(Reuters)
Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
US respiratory virus activity (CDC Respiratory Illnesses)
Flu in US continues to decline but still packs a punch (CIDRAP)
Weekly surveillance report: clift notes (CDC FluView)
Respiratory virus activity levels (CDC Respiratory Illnesses)
FDA-CDC-DOD: 2025-2026 influenza vaccine composition (FDA)
RSV: Waste water scan for 11 pathogens (WastewaterSCan)
Weekly US influenza surveillance report (CDC FluView)
US respiratory virus activity (CDC Respiratory Illnesses)
RSV-Network (CDC Respiratory Syncytial virus Infection)
Waste water scan for 11 pathogens (WastewaterSCan)
COVID-19 deaths (CDC)
COVID-19 national and regional trends (CDC)
COVID-19 variant tracker (CDC)
SARS-CoV-2 genomes galore (Nextstrain)
Lower levels of household transmission of sars-cov-2 omicron variant of concern vs wild type: an interplay between transmissibility and immune status (JID)
Does COVID-19 vaccination reduce the risk and duration of post COVID-19 condition?(European Centre for Disease Prevention and Control)
COVID-19 vaccination reduces risk of ‘long COVID’ in adults (European Centre for Disease Prevention and Control)
Vaccination cuts the risk of long COVID 27%, review suggests (CIDRAP)
Interim clinical considerations for use of covid-19 vaccines in the United States (CDC: Vaccines and immunizations)
Where to get pemgarda (Pemgarda)
EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
Fusion center (Prime Fusions)
CDC Quarantine guidelines (CDC)
NIH COVID-19 treatment guidelines (NIH)
Drug interaction checker (University of Liverpool)
Infectious Disease Society guidelines for treatment and management (ID Society)
The effect of nirmatrelvir-ritonavir on short- and long-term adverse outcomes from covid-19 among patients with kidney disease (ofid)
Molnupiravir safety and efficacy (JMV)
Convalescent plasma recommendation for immunocompromised (ID Society)
What to do when sick with a respiratory virus (CDC)
When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)
Managing healthcare staffing shortages (CDC)
Steroids, dexamethasone at the right time (OFID)
Anticoagulation guidelines (hematology.org)
Daniel Griffin’s evidence based medical practices for long COVID (OFID)
Long COVID hotline (Columbia : Columbia University Irving Medical Center)
The answers: Long COVID
Effect of pulmonary rehabilitation for patients with long COVID-19(Therapeutic Advances in Respiratory Disease)
Wearable data reveals distinct characteristics of individuals with persistent symptoms after a SARS-CoV-2 infection(npj digital medicine)
Long Covid office ‘will be closing,’ Trump administration announces(Politico)
Commencing the reduction of the federal bureaucracy(White House) Musk said no one has died since aid was cut. That isn’t true.(NY Times)
Letters read on TWiV 1204
Dr. Griffin’s COVID treatment summary (pdf)
Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1203: What's old is flu again Mar 23, 2025

TWiV explains why RFK Jr.’s proposal to let H5N1 infections in birds ‘rip’ is a bad idea, phase 1/2 trial of combined influenza/COVID mRNA vaccines, and how your first influenza virus exposure shapes the B cell response to influenza vaccination 50 years later.

Hosts: Vincent Racaniello, Rich Condit, and Brianne Barker

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

Links for this episode

Support science education at MicrobeTV
ASV 2025
RFK Jr. says let H5N1 rip through flocks (NY Times)
Combined flu/COVID mRNA vaccine (Nat Comm)
Rare syndrome after COVID vaccination (NY Times, medRxiv)
Imprinting lasts 50 years (Immunity)
Imprinting protects against H5N1 and H7N9 (Science)
Letters read on TWiV 1203
Timestamps by Jolene Ramsey. Thanks!

Weekly Picks

Brianne – Node-Focal Plane Image Competition Rich – Periodic cooking of eggs Vincent – The use of placebo controls in clinical trials

Listener Picks

Anne – Everything is Tuberculosis by John Green

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1202: Clinical update with Dr. Daniel Griffin Mar 22, 2025

In his weekly clinical update, Dr. Griffin and Vincent Racaniello rue about the unknowns of Sudan disease and new cases of paralytic polio, discuss the growing measles outbreak, exposure of newborns to measles, the FACTS about vaccination, high pathogenic influenza in dairy cows and cats, RFK’s statement “just let the virus rip through the hens” before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, where to find PEMGARDA, what happens when antiviral therapy is delayed, provides information for Columbia University Irving Medical Center’s long COVID treatment center, where to go for answers to your long COVID questions, long COVID interventions and the relationship between EBV and long COVID.

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

Links for this episode

New cases of poliomyelitis (GPEI)
Polio in Africa (CIDRAP)
Program for Monitoring Emerging Diseases (PROMED)
ProMED Subscriptions (PROMED)
Measles infected baby and exposes 12 (NY Post)
Measles 159 in Texas…. (Texas Health and Human Services)
2025 Measles outbreak guidance (New Mexico Health)
Get the FACTS about measles (NY State Department of Health)
Revising US MMR vaccine recommendations amid changing domestic risks (JAMA Network)
Long-term dynamics of measles virus–specific neutralizing antibodies in children vaccinated before 12 months of age (CID)
Newborns exposed to measles in Texas hospital (NBC News)
Newborns exposed in West Texas measles outbreak (CIDRAP)
Measles (CDC Measles (Rubeola))
Measles vaccine (CDC Measles (Rubeola))
Presumptive evidence of measles immunity (CDC)
Contraindications and precautions to measles vaccination (CDC)
Measles (CDC Measles (Rubeola))
Increase in global and domestic measles cases and outbreaks: (CDC:)
The impact of influenza A H5N1 virus infection in dairy cows (Nature: Research Gate)
Payment of indemnity and compensation for highly pathogenic avian Influenza (Federal Register)
FDA or USDA: Kennedy’s alarming prescription for bird flu on poultry farms(NY Times)
Some of NYC’s 500K stray cats could be infected with bird flu(NY Post)
Two NYC cats dead from avian flu, including 8-month-old kitten:(NY Post)
H7N9 avian flu strikes Mississippi broiler farm(CIDRAP) Highly pathogenic avian influenza diagnosed in Mississippi poultry flock (Mississippi Board of Animal Health)
Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
US respiratory virus activity (CDC Respiratory Illnesses)
Weekly surveillance report: cliff notes (CDC FluView)
The burden of all-cause mortality following influenza-associated hospitalizations (CID)
FDA-CDC-DOD: 2025-2046 influenza vaccine composition (FDA)
FDA announces flu strain picks for next season(CIDRAP)
RSV: Waste water scan for 11 pathogens (WastewaterSCan)
Weekly US influenza surveillance report (CDC FluView)
US respiratory virus activity (CDC Respiratory Illnesses)
RSV-Network (CDC Respiratory Syncytial virus Infection)
Waste water scan for 11 pathogens (WastewaterSCan)
COVID-19 deaths (CDC)
COVID-19 national and regional trends (CDC)
COVID-19 variant tracker (CDC)
SARS-CoV-2 genomes galore (Nextstrain)
COVID-19 antiviral medication use among pregnant and recently pregnant US outpatients (CID)
Where to get pemgarda (Pemgarda)
EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
Fusion center (Prime Fusions)
CDC Quarantine guidelines (CDC)
NIH COVID-19 treatment guidelines (NIH)
Drug interaction checker (University of Liverpool)
Infectious Disease Society guidelines for treatment and management (ID Society)
Molnupiravir safety and efficacy (JMV)
Convalescent plasma recommendation for immunocompromised (ID Society)
What to do when sick with a respiratory virus (CDC)
When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)
Managing healthcare staffing shortages (CDC)
Steroids,dexamethasone at the right time (OFID)
Anticoagulation guidelines (hematology.org)
Daniel Griffin’s evidence based medical practices for long COVID (OFID)
Long COVID hotline (Columbia : Columbia University Irving Medical Center)
The answers: Long COVID TGFβ links EBV to multisystem inflammatory syndrome in children(Nature)
Letters read on TWiV 1202
Dr. Griffin’s COVID treatment summary (pdf)
Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1201: Booster shots with Adam Ratner Mar 16, 2025

Infectious diseases physician and author of ‘Booster Shots’ Adam Ratner joins TWiV to discuss measles, measles vaccination, how to approach anti-vaccine sentiment, and the uncertain future of children’s’ health.

Hosts: Vincent Racaniello, Brianne Barker, and Jolene Ramsey

Guest: Adam Ratner

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Links for this episode

Support science education at MicrobeTV
Booster Shots by Adam Ratner
The Cutter Incident by Paul Offit
Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1200: Clinical update with Dr. Daniel Griffin Mar 15, 2025

In his weekly clinical update, Dr. Griffin and Vincent Racaniello bemoan the continued outbreak of Sudan virus and growing number of paralytic polio cases before discussing growing measles outbreak in the US and Europe, the vaccine, an interview with a parent whose child died of measles infection, adverse effects of vaccination and how parents do not think they have accurate information about “bird flu” before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, where to find PEMGARDA, what happens when antiviral therapy is delayed, provides information for Columbia University Irving Medical Center’s long COVID treatment center, where to go for answers to your long COVID questions, long COVID interventions and the benefits of antiviral therapies on post acute SARS-Cov-2 infection sequelae.

Subscribe (free): Apple Podcasts, RSS, email

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Links for this episode

Sudan virus disease(WHO)
New cases of poliomyelitis (GPEI)
Measles 159 in Texas…. (Texas Health and Human Services)
2025 Measles outbreak guidance (New Mexico Health)
First cases of measles in Oklahoma (Oklahoma)
Measles case on Long Island (CBS News)
Public health confirms measles case in Los Angeles County (County of Los Angeles Public Health)
Measles exposure (Department of public health: City of Philadelphia)
Where US measles outbreaks are spreading (New York Times)
Statement from the chief public health officer of Canada on the increase in measles cases and the risk to people in Canada(Health Canada)
Measles and rubella monthly report (ecdc)
Measles on the rise again in Europe (EurekAlert)
Measles: symptoms, spread & SSPE | Doctors Talk | Children’s Hospital of Philadelphia (YouTube)
Measles (CDC Measles (Rubeola))
Adverse events associated with childhood vaccines: evidence bearing on causality (NLM: NCBI)
Measles vaccination: know the facts? (Infectious Diseases Society of America)
Deaths following vaccination: What does the evidence show? (Vaccine)
Facts and myths about measles (LANCET: Infectious Diseases)
His daughter was America’s first measles death in a decade (The Atlantic)
Less than half of parents think they have accurate information about bird flu (EurekAlert)
Many US parents feeluninformed about avian flu risks (CIDRAP)
Trends in respiratory pathogen testing at us children’s hospital(JAMA Network)
Changes in respiratory viral testing before and after the covid-19 pandemic(JAMA Network)
Free COVID-19 test program stops taking orders (Health day)
Human cases of highly pathogenic avian influenza a(h5n1) — California, September–December 2024 (CDC MMWR)
Letters read on TWiV 1198 37:56
Dr. Griffin’s COVID treatment summary (pdf)
Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1199: Loosely contained Mar 09, 2025

TWiV covers a second death over 150 cases of measles in Texas, utter failure of removal of type 2 poliovirus from OPV, more OPV doses administered in Gaza, second Ebola outbreak in Sudan, vaccine being tested, Trump administration cancels $400 million in grants to Columbia University, bat-infecting merbecovirus that binds human ACE2 and infects human cells, and innate immune sensing of rotavirus by intestinal epithelial cells leads to diarrhea.

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler

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Links for this episode

Support science education at MicrobeTV
ASV 2025
Second child dies of measles (NY Times)
Over 150 measles cases in Texas (Texas DSHS)
Utter failure of removal of OPV2 from OPV (Science)
Over 600,000 doses of OPV administered in Gaza (polioeradication)
Second outbreak of Sudan Ebola in Uganda (IAVI)
Columbia grants canceled by administration (NBC News)
Bat merbecovirus also infects human cells via Ace2 (Cell)
Recent virus research, was proper containment used? (NY Times)
Innate immune sensing of rotatvirus leads to diarrhea (Cell Host Microbe)
Timestamps by Jolene Ramsey. Thanks!

Weekly Picks

Kathy – Mice cry out when they urinate, and give mouth to mouth resuscitation Rich – Firefly Aerospace Alan – Strong Museum of Play Vincent – How a PhD student’s lab size affects their chance of future academic success

Listener Picks

Larry – James Harrison’s rare blood protected many infants

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1198: Clinical update with Dr. Daniel Griffin Mar 08, 2025

In his weekly clinical update, Dr. Griffin with Vincent Racaniello deliberate the effect of the absence of US foreign aid on the Ebola outbreak in Uganda and death of two children, continued use of nOPV2 in Gaza and the utter failure of type 2 poliovirus removal from the oral poliovirus vaccine, growing measles outbreak in the US including the death of a second child, measles infection parties, the use of fat soluble vitamin A and fish liver oil as anti-viral therapies as well as the history and proven safety of the measles vaccine before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, where to find PEMGARDA, what happens when antiviral therapy is delayed, provides information for Columbia University Irving Medical Center’s long COVID treatment center, and where to go for answers to your long COVID questions, long COVID interventions.

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

Links for this episode

African region: outbreaks and other emergencies(WHO Bitstream)
US withdrawal……death of 4 year old children from Ebola (CIDRAP)
Science and health writer Apoorva Mandavilli (NY Times)
US foreign aid pullback……death of 4 year old in Uganda (NY Times)
Another Ebola death reported in Kampala (Monitor)
African region: outbreaks and other emergencies(WHO Bitstream)
More than 600,000 doses of nOPV2 in Gaza last week (GPEI)
Utter failure of the global withdrawal of the Sabin oral poliovirus type 2 vaccine 2016 (Science)
Measles 159 in Texas…. (Texas Health and Human Services)
Second child dies in the growing measles outbreak (Washington Post)
2025 Measles outbreak guidance (New Mexico Health)
Lea county resident tests positive for measles after death (New Mexico Health)
Robert F Kennedy Jr article series (The Guardian)
Kennedy Jr backtracks and says US measles outbreak is now a ‘top priority’ for health department (The Guardian)
RFK Jr. Says Ending Measles Outbreak Is Priority (Wall Street Journal)
RFK Jr. Sparks Anti-Vaxxer Anger: ‘No Different Than Fauci’ (Newsweek)
Amid West Texas measles outbreak, vaccine resistance hardens (Washington Post)
How to protect your children during a measles outbreak (healthychildren.org)
Measles vaccination protects against virus infection and other infections (Science)
MEASLES(WHO)
C.D.C. Sends ‘Disease Detectives’ to Texas for Measles Outbreak(NY Times)
Studies on an attenuated measles-virus vaccine — clinical, virologic and immunologic fffects of vaccine in institutionalized children(NEJM)
Studies on an attenuated measles-virus vaccine — clinical and antigenic effects of vaccine in institutionalized children (NEJM)
Studies on an attenuated measles-virus vaccine — administration of vaccine by several routes (NEJM)
Studies on an attenuated measles-virus vaccine — clinical, antigenic and prophylactic effects of vaccine in institutionalized and home-dwelling children(NEJM)
Studies on an attenuated measles-virus vaccine — clinical, antigenic and prophylactic effects of vaccine in institutionalized children(NEJM)
Studies on an attenuated measles-virus vaccine — clinical, antigenic and prophylactic effects of vaccine in home-dwelling children (NEJM)
Studies on an attenuated measles-virus vaccine — general summary and evaluation of the results of vaccination(NEJM)
Cooperative measles vaccine field trial (Pediatrics)
A collaborative study of measles vaccines in five united states communities (American Journal of Public Health)
A field trial of inactivated measles virus vaccine in young school children(JAMA Network)
Prevention of natural and experimental measles with the vaccine(JAMA Network)
A field trial in young school children(JAMA Network)
Measles vaccination before the measles-mumps-rubella vaccine (American Journal of Public Health)
The status of measles vaccines (Journal of the National Medical Association)
Measles, mumps, and rubella (mmr) vaccination: what everyone should know (CDC Vaccines & Immunizations)
Clinical review memo- measles, mumps, rubella (FDA)
History of the measles vaccine (WHO)
Vitamin A and the measles (Yahoo! News)
As measles spreads, Kennedy embraces remedies like cod liver oil (NY Times)
Parents are holding ‘measles parties’ in the U.S., alarming healthexperts(Global News)
Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
US respiratory virus activity (CDC Respiratory Illnesses)
Weekly surveillance report: cliff notes (CDC FluView)
RSV: Waste water scan for 11 pathogens (WastewaterSCan)
Weekly US influenza surveillance report (CDC FluView)
US respiratory virus activity (CDC Respiratory Illnesses)
RSV-Network (CDC Respiratory Syncytial virus Infection)
Waste water scan for 11 pathogens (WastewaterSCan)
COVID-19 deaths (CDC)
COVID-19 national and regional trends (CDC)
COVID-19 variant tracker (CDC)
SARS-CoV-2 genomes galore (Nextstrain)
Interim estimates of 2024–2025 covid-19 vaccine effectiveness among adults aged ≥18 years — vision and ivy networks, September 2024–January 2025 (CDC MMWR)
Where to get pemgarda (Pemgarda)
EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
Fusion center (Prime Fusions)
CDC Quarantine guidelines (CDC)
NIH COVID-19 treatment guidelines (NIH)
Drug interaction checker (University of Liverpool)
Infectious Disease Society guidelines for treatment and management (ID Society)
Molnupiravir safety and efficacy (JMV)
Convalescent plasma recommendation for immunocompromised (ID Society)
What to do when sick with a respiratory virus (CDC)
When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)
Managing healthcare staffing shortages (CDC)
Steroids, dexamethasone at the right time (OFID)
Anticoagulation guidelines (hematology.org)
Effect of early and delayed treatment with remdesivir on mortality in patients hospitalized with COVID-19 (OFID)
Daniel Griffin’s evidence based medical practices for long COVID (OFID)
Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID
Letters read on TWiV 1198
Dr. Griffin’s COVID treatment summary (pdf)
Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1197: The long and short of influenza Mar 02, 2025

TWiV reviews passing of Ann Palmenberg, deadly illness in western Congo, US disruption of mpox and ebolavirus programs, first measles death in Texas outbreak, flu vaccine selection meeting postponed, US withdraws from polio, malaria, HIV programs and more, clade 2.3.4.4b H5N1 viruses have a long HA stalk, and systems vaccinology to identify predictors of durable antibody response to multiple vaccines in humans.

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Brianne Barker

Subscribe (free): Apple Podcasts, RSS, email

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Links for this episode

Support science education at MicrobeTV
ASV 2025
Ann Palmenberg dies (Cress)
Ann at Chumakov Symposium (YouTube)
Unknown illness in Congo (NY Times)
Bad news about mpox outbreak (NPR)
US interrupts Ebola prevention program (NPR)
First measles death in Texas (Texas Trib)
Flu vaccine selection meeting canceled (NY Times)
US ends funding for polio, HIV, malaria and more (NY Times)
Clade 2.3.4.4b H5N1 neuraminidase has a long stalk (mBio)
Predictors of durable antibody responses to vaccines (Nat Immunol)
Review of adjuvants (Vaccinol Methods Vacc Res)
Timestamps by Jolene Ramsey. Thanks!

Weekly Picks

Brianne – Video of the Northern Lights from Space Rich – Vaccination for Sudan Ebola virus disease Alan – Specialized moth wing scales give it 3-D camouflage (news and paper) Vincent – WHO Recommendations for Influenza Vaccine Composition for the 2025-2026 Northern Hemisphere Influenza Season

Listener Picks

Gerry – Eukaryotic Transcription Anne – The science of the solar system

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1196: Clinical update with Dr. Daniel Griffin Mar 01, 2025

In his weekly clinical update, Dr. Griffin and Vincent Racaniello lament about the downfall of public health from “postponement” of the advisory committee on immunization practices and the FDA VRBPAC influenza strain selection meetings to how the communication pause prevents public notice of NIH study section meetings, and withdrawal of CDC promotions for the ‘flu vaccine’ before discussing the end of Ebola outbreak in Uganda, funding from Saudi Arabia for polio eradication, the continuing and growing measles outbreak in the US including misinformation from the Secretary of HHS, highly pathogenic avian flu and its economic effect, ie the cost of eggs before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, where to find PEMGARDA, an update of Paxlovid administration, provides information for Columbia University Irving Medical Center’s long COVID treatment center, where to go for answers to your long COVID questions, long COVID interventions and FDA approval of adjuvanted Novovax COVID vaccine.

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Links for this episode

Phantom ACIP (CDC)
Postponement of ACIP…..hummmm (STATNews)
Influenza Strain selection VRBPAC cancelled (Reuters)
How NIH funded research is impacted by government communication pause (NY Times)
Can be reviewed but still no money (STATNews)
Final push to end Ebola in Uganda (WHO Uganda)
Saudi Arabia sponsors polio eradication effort (GPEI))
$500 million from Saudi Arabia to immunize 370 million children against polio (CIDRAP)
Measles 124 in Texas…. (Texas Health and Human Services)
A Texas child who was not vaccinated has died of measles(AP News)
The Measles book-(Apple Books)
Measles vaccination protects against virus infection and other infections (Science)
Measles deadliest sequelae (MEDPAGE TODAY)
Measles cases and outbreaks (CDC Measles)
Unvaccinated Child Dies of Measles in Texas Outbreak(NY Times)
Texas child is first reported US measles death in a decade as outbreak hits more than 130 (Reuters)
Trump’s cabinet meeting: Kennedy Shocker “Not unusual”……..seriously! (YouTube)
First measles death reported in Texas as Kennedy downplays the outbreak (NBC News)
Measles cliff notes: symptoms timeline (Substackdn)
Annual state immunization report (Texas Health and Human Services)
Measles imported into Kentucky…….no tariffs? (Commonwealth of Kentucky)
Egg shortage affect flu shots? (MEDPAGE TODAY)
Which Came First, the Chicken Slaughter or the Egg Shortage(Wall Street Journal)
Avian Influenza in Birds: Causes and How It Spreads (CDC Avian Influenza)
Agriculture Secretary Brooke Rollins: My Plan to Lower Egg Prices (Wall Street Journal)
Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
US respiratory virus activity (CDC Respiratory Illnesses)
Weekly surveillance report: clift notes (CDC FluView)
RSV: Waste water scan for 11 pathogens (WastewaterSCan)
Weekly US influenza surveillance report (CDC FluView)
US respiratory virus activity (CDC Respiratory Illnesses)
Trump administration yanks CDC flu vaccine campaign(NPR)
RSV-Network (CDC Respiratory Syncytial virus Infection)
New wild to mild campaign drives key message to tame flu and reset expectations
(CDC Influenza)
Waste water scan for 11 pathogens (WastewaterSCan)
COVID-19 deaths (CDC)
COVID-19 national and regional trends (CDC)
COVID-19 variant tracker (CDC)
SARS-CoV-2 genomes galore (Nextstrain)
Effectiveness of the original monovalent messenger RNA Coronavirus Disease 2019 (COVID-19) vaccination series against hospitalization for COVID-19–Associated venous thromboembolism (JID)
Where to get pemgarda (Pemgarda)
EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
Infusion center (Prime Fusions)
CDC Quarantine guidelines (CDC)
NIH COVID-19 treatment guidelines (NIH)
Drug interaction checker (University of Liverpool)
Demographic variation in US outpatient hydroxychloroquine and ivermectin use during the COVID-19 pandemic (HealthAffairs)
Paxlovid update (Pfizer)
Infectious Disease Society guidelines for treatment and management (ID Society)
Alleviation of COVID-19 symptoms and reduction in healthcare utilization among high-risk patients treated With nirmatrelvir/ritonavir (NMV/R) (CID)
Molnupiravir safety and efficacy (JMV)
Convalescent plasma recommendation for immunocompromised (ID Society)
What to do when sick with a respiratory virus (CDC)
When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)
Managing healthcare staffing shortages (CDC)
Steroids, dexamethasone at the right time (OFID)
Anticoagulation guidelines (hematology.org)
Daniel Griffin’s evidence based medical practices for long COVID (OFID)
Long COVID hotline (Columbia : Columbia University Irving Medical Center)
The answers: Long COVID
Interventions for Long COVID: A Narrative Review (Journal of General Internal Medicine)
COVID-19 vaccination and odds of post–COVID-19 condition symptoms in children aged 5 to 17 Years (JAMA Network)
Novavax COVID-19 vaccine, adjuvanted (FDA)
Letters read on TWiV 1196
Dr. Griffin’s COVID treatment summary (pdf)
Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1195: Dickson Despommier, parasitologist without borders Feb 23, 2025

The entire TWiV team comes together to pay tribute to Dickson Despommier, then reviews antibodies to H5N1 virus in veterinarians working with dairy cattle, Elisabeth Bik donates prize money for data integrity analyses, measles outbreak in Texas, and use of an alternative genetic code by human microbiome phages.

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, Kathy Spindler, Brianne Barker, Daniel Griffin, Angela Mingarelli, and Jolene Ramsey

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

Links for this episode

Support science education at MicrobeTV
ASV 2025
Livestream tribute to Dickson (Office Hours)
Dickson’s Wikipedia page
Dickson’s obituary (NY Times)
Dickson websites: trichinella.org, thelivingriver.org, fordhamopolis.com, despommierphotoart.com
Alan’s tribute to Dickson (alandove.com)
H5N1 seroprevalence (MMWR)
Elisabeth Bik donates prize money (Science)
Measles outbreak in Texas (Texas DSHS)
Human microbiome phages use alternative genetic code (Nat Comm)
Letters (mostly not) read on TWiV 1195 – all about Dickson
Timestamps by Jolene Ramsey. Thanks!

Weekly Picks

Angela – Rare spotting of humpback anglerfish “diablo negro” (Melanocetus johnsonii) in Tenerife, Canary Islands. First time ever observed alive! Brianne – Moonwalking with Einstein inspired by reading NY Times article about Recent memory champ Kathy – Witness History 9 minute podcasts Rich – APOD: Perijove 11: Passing Jupiter Alan – Ecological succession on abandoned farmland Jolene – Parasitic Diseases Lectures and first 27 episodes of This Week in Parasitism Vincent – The New City

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1194: Clinical update with Dr. Daniel Griffin Feb 22, 2025

In his weekly clinical update, Dr. Griffin and Vincent Racaniello reminiscence about Dickson before discussing discharging Ebola patients, another announcement of emergency measures to control polio spread and the third nOPV2 vaccination campaign in Gaza in less than 6 months, the measles outbreak in the US, vaccination campaign for chickens against high pathogenic avian flu before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, where to find PEMGARDA, an update of Paxlovid administration provides information for Columbia University Irving Medical Center’s long COVID treatment center, and where to go for answers to your long COVID questions.

Subscribe (free): Apple Podcasts, RSS, email

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Links for this episode

In memory of Dickson (NY Times)
All Ebola patients discharged in Uganda (DG Alerts)
Uganda discharges Ebola patients (WHO Uganda)
Emergency measures to stop polio…..isn’t this the same plan as last year? (GPEI))
A third nOPV2 campaign…..but I thought OPV stops transmission (Reuters)
Worst outbreak of measles in 30 years for Texas….go big or go home! (AP News)
Measles 58 in Texas…. (Texas Health and Human Services)
High pathogenic avain influenza virus infection of indoor domestic cats (CDC MMWR)
Avian influenza in dairy cattle in Arizona (AZEIN)
Third avian flu spillover! (CIDRAP)
No vaccine hesitancy in chickens…..vaccinate all! (Science)
Zoetis to supply conditionally licensed avian influenza H5N1 vaccine for chickens (Zoetis)
High path avian influenza in mammals (USDA: Animal and plant health inspection service)
How to vaccinate your chicken (WikiHow)
Vaccine failure due to poor administration.(the poultry site)
Human cases of H5N1 in US rise to 4 (CBS News)
Canada’s buying vaccine as US rats become infected (CIDRP)
Canada purchases avian influenza vaccine for those at high risk (Canada Public Health)
Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
How the communications pause endangered us about influenza (AP News)
Most intense flu season in 15 years (AP News)
US respiratory virus activity (CDC Respiratory Illnesses)
Weekly surveillance report: clift notes (CDC FluView)
RSV: Waste water scan for 11 pathogens (WastewaterSCan)
Weekly US influenza surveillance report (CDC FluView)
RSV-Network (CDC Respiratory Syncytial virus Infection)
US respiratory virus activity (CDC Respiratory Illnesses)
COVID-19 case fatality rate and infection fatality rate from 2020 to 2023 (Journal of Infection and public health)
Waste water scan for 11 pathogens (WastewaterSCan)
COVID-19 deaths (CDC)
COVID-19 national and regional trends (CDC)
COVID-19 variant tracker (CDC)
SARS-CoV-2 genomes galore (Nextstrain)
Where to get pemgarda (Pemgarda)
EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
Fusion center near you….if in NY (Prime Fusions)
CDC Quarantine guidelines (CDC)
NIH COVID-19 treatment guidelines (NIH)
Drug interaction checker (University of Liverpool)
Paxlovid update (Pfizer)
Infectious Disease Society guidelines for treatment and management (ID Society)
A randomized, double-blind, Phase 1, single- and multiple-dose placebo-controlled study of the safety and pharmacokinetics of IN-006, an inhaled antibody treatment for COVID-19 in healthy volunteers (eBioMedicine)
Ensitrelvir for the Treatment of Nonhospitalized Adults with COVID-19 (CID)
Molnupiravir safety and efficacy (JMV)
Convalescent plasma recommendation for immunocompromised (ID Society)
What to do when sick with a respiratory virus (CDC)
When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)
Managing healthcare staffing shortages (CDC)
Steroids, dexamethasone at the right time (OFID)
Anticoagulation guidelines (hematology.org)
Daniel Griffin’s evidence based medical practices for long COVID (OFID)
Long COVID hotline (Columbia : Columbia University Irving Medical Center)
The answers: Long COVID
Letters read on TWiV 1194
Dr. Griffin’s COVID treatment summary (pdf)
Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1193: HPV or not to B Feb 16, 2025

TWiV reviews a facility accident that killed monkeys, new bird blu genotype found in Nevada dairy cattle, Argentina plans to leave WHO, yellow fever on the rise, dynamics of HPV infections in women, and Epstein-Barr virus protein targets B cell receptor for degradation.

Hosts: Vincent Racaniello, Alan Dove, and Angela Mingarelli

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

Links for this episode

Support science education at MicrobeTV
ASV 2025
Accident kills monkeys at SC research supply facility (Science)
D1.1 Genotype in Dairy Cattle in Nevada (APHIS)
Argentina to leave WHO (CIDRAP)
Yellow fever on the rise (CIDRAP)
HPV dynamics in women (PLoS Biol)
EBV protein degrades B cell receptor (PNAS)
Letters read on TWiV 1193
Timestamps by Jolene Ramsey. Thanks!

Weekly Picks

Angela – Mitochondrial swap from cancer to immune cells thwarts anti-tumour defences (one, two) Alan – A little adventure game Vincent – The Staggering Success of Vaccines

Listener Picks

John – Percy Lavon Julian Debi – Don’t Look Up

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1192: Clinical update with Dr. Daniel Griffin Feb 15, 2025

In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss confirmation of Robert F Kennedy as HHS sectary, mpox, Ebola, how the American people support vaccine development and administration, the measles outbreak in the US-Texas, Georgia and influenza: the number of human infections, high avian flu in mammals, house cats and dairy cows before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, where to find PEMGARDA, an update of Paxlovid administration provides information for Columbia University Irving Medical Center’s long COVID treatment center, where to go for answers to your long COVID questions, how long COVID varies between children and adults and if viral infection reduces telomere length in sperm.

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

Links for this episode

Confirmation of RFK, Jr as HHS sect (NY Times)
Did you know mpox in NY?….(Reuters)
Mpox in sex workers in the Congo and in NY (CIDRAP)
9 confirmed, 265 suspected Ebola cases in Uganda (AP news)
WHAT!? Support vaccines: availability and development. WHAT? (Businesswire)
Measles rising in the unvaccinated. You mean the vaccines does something positive? (ABC News)
Measles in Texas….go big or go home (Texas Health and Human Services)
Vaccination Conscientious exemptions in Texas (Texas Health and Human Services)
2, 6, 14 measles hospitalizations in Texas (CNN)
Decreases in childhood vaccinations SchoolVaxView(CDC)
2 when 24 cases of measles in two weeks (Texas Health and Human Services)
Measles in small town Texas (NY Times)
Measles in the US Texas, Georgia, Rhode Island, New York, New Mexico:
Elimination of measles (JID)
Influenza taxonomy (NCBI)
H5N9 in commercial duck farm, California (American Animal Hospital Association)
Second type of bird flu circulating in ducks (Scientific Amercia)
Variant H1N2 flu in Iowa (CIDRAP)
All types of influenza (CDC Influenza)
Bird flu in the zoos: Bronx and Queens (Gothamist)
High path avian influenza in mammals (USDA: Animal and plant health inspection service)
Bird flu in house cats…..I tawt I taw a puddy tat (KFF Health News)
New strain of influenza in dairy cows (AP News)
Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
How the communications pause endangered us about influenza (AP News)
Most intense flu season in 15 years (AP News)US respiratory virus activity (CDC Respiratory Illnesses)
Weekly surveillance report: clift notes (CDC FluView)
RSV: Waste water scan for 11 pathogens (WastewaterSCan)
Weekly US influenza surveillance report (CDC FluView)
RSV-Network (CDC Respiratory Syncytial virus Infection)
10 year surveillance of RSV hospitalization in adults(JID)
Seasonality of RSV: 2017-2023(CDC: MMWR)
What doctors wish patients know about RSV (AMA)
US respiratory virus activity (CDC Respiratory Illnesses)
Waste water scan for 11 pathogens (WastewaterSCan)
COVID-19 deaths (CDC)
COVID-19 national and regional trends (CDC)
COVID-19 variant tracker (CDC)
SARS-CoV-2 genomes galore (Nextstrain)
Where to get pemgarda (Pemgarda)
EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
Fusion center near you….if in NY (Prime Fusions)
CDC Quarantine guidelines (CDC)
NIH COVID-19 treatment guidelines (NIH)
Drug interaction checker (University of Liverpool)
Paxlovid update (Pfizer)
Infectious Disease Society guidelines for treatment and management (ID Society)
Molnupiravir safety and efficacy (JMV)
Convalescent plasma recommendation for immunocompromised (ID Society)
What to do when sick with a respiratory virus (CDC)
When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)
Managing healthcare staffing shortages (CDC)
Steroids, dexamethasone at the right time (OFID)
Anticoagulation guidelines (hematology.org)
Daniel Griffin’s evidence based medical practices for long COVID (OFID)
Long COVID hotline (Columbia : Columbia University Irving Medical Center)
The answers: Long COVID
Proportion of Long COVID incidence in adults and children (CID)
SARS-CoV-2 infection effects sperm telomere length (Journal of Assisted Reproduction and Genetics)
Pediatric gastrointestinal tract outcomes during the postacute phase of COVID-19c]\ (JAMA Network)
Letters read on TWiV 1192
Dr. Griffin’s COVID treatment summary (pdf)
Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

TWiV 1191: The pandemic duo Feb 09, 2025

TWiV reviews freezes and unfreezes of US government grants, how prior COVID-19 vaccination prevents over-reaction of the innate immune response during infections, and how bat genomes illuminate adaptations to viral tolerance and disease resistance.

Hosts: Vincent Racaniello and Alan Dove

Subscribe (free): Apple Podcasts, RSS, email

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Links for this episode

Support science education at MicrobeTV
ASV 2025
NIH freezes (ScienceAdviser)
Is your research on Trump’s hit list? (ScienceInsider)
Prior COVID-19 vaccination tames innate responses (Sci Transl Med)
Bat genomes illuminate viral tolerance and disease resistance (Nature)
Letters read on TWiV 1191
Timestamps by Jolene Ramsey. Thanks!

Weekly Picks

Alan – NOAA Space Weather Prediction Center dashboards Vincent – He created a hummingbird paradise in his backyard

Listener Picks

Christiane – Contact your members of Congress about the Pause in Federal Grant Funding Charles – What’s trending in the world of pseudoscience

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1190: Clinical update with Dr. Daniel Griffin Feb 08, 2025

In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss changes in access to public health information and aid mechanisms such as the return of MMWR, the largest tuberculosis outbreak in the US ever, lack of USAID in fighting Marburg and Ebola outbreaks in Africa, discussing if avian influenza virus is airborne, how eggs are effected and the emergence of second spillover into dairy cattle, how the difference between nOPV2 and Sabin OPV2 is a minor reduction in the association of vaccine associated paralytic poliomyelitis before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, where to find PEMGARDA, an update of Paxlovid administration provides information for Columbia University Irving Medical Center’s long COVID treatment center, where to go for answers to your long COVID questions, how children may be affected by long COVID and if SARS-CoV-2 and other inflammatory syndromes increase the risk of Alzheimer’s disease.

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Links for this episode

The return of MMWR (CDC)
Largest tuberculosis outbreak ever in the US (Kansas Department of Health and Environment)
Marburg virus outbreak in Tanzania (Doctors without borders)
No USAID, Ebola outbreak in Uganda spreads (CBS News)
WHO accelerates efforts to Ebola response in Uganda (WHO: Uganda)
Global partners enable access to vaccine and treatment for Ebola outbreak in Uganda (WHO)
Ventilation and respiratory viruses (CDC National Institute for Occupational safety and health)
Is bird flu flying through the air…..is the virus literally airborne? (NY Times)
Is bird flu like measles (American Journal of Epidemiology)
Indoor safety guideline (Herokuapp)
Dairy herds in Nevada have influenza! (CIDRAP)
Do your eggs have H5N1? (NY Times)
New genotye D1.1 of avian flu in dairy cattle(USDA Animal and Plant Health Inspection Service)
Second spillover of avian flu into dairy cattle….does this story sound familiar? (CIDRAP)
Impact of using nOPV2 in mass vaccination campaigns? (JID)
Waste water scan for 11 pathogens (WastewaterSCan)
US respiratory virus activity (CDC Respiratory Illnesses)
Weekly surveillance report: clift notes (CDC FluView)
As flu increases so do deaths in kids (CIDRAP)
People most impacted by respiratory viruses (CDC)
Co-infection with SARS-CoV-2 and influenza A/B (BMC Infectious Diseases)
Oseltamivir reduces 30-Day mortality in older adults with Influenza (OFID)
RSV: Waste water scan for 11 pathogens (WastewaterSCan)
RSV-Network (CDC Respiratory Syncytial virus Infection)
US respiratory virus activity (CDC Respiratory Illnesses)
Waste water scan for 11 pathogens (WastewaterSCan)
COVID-19 deaths (CDC)
COVID-19 national and regional trends (CDC)
COVID-19 variant tracker (CDC)
SARS-CoV-2 genomes galore (Nextstrain)
Where to get pemgarda (Pemgarda)
EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
Fusion center near you….if in NY (Prime Fusions)
CDC Quarantine guidelines (CDC)
NIH COVID-19 treatment guidelines (NIH)
Drug interaction checker (University of Liverpool)
Paxlovid update (Pfizer)
Infectious Disease Society guidelines for treatment and management (ID Society)
Molnupiravir safety and efficacy (JMV)
Convalescent plasma recommendation for immunocompromised (ID Society)
What to do when sick with a respiratory virus (CDC)
When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)
Managing healthcare staffing shortages (CDC)
Steroids, dexamethasone at the right time (OFID)
Anticoagulation guidelines (hematology.org)
Daniel Griffin’s evidence based medical practices for long COVID (OFID)
Long COVID hotline (Columbia : Columbia University Irving Medical Center)
The answers: Long COVID
Long COVID Recovery Program with Zara Dureno, BA, MOT
Long COVID pevalence and associated activity limitation in US children
(JAMA Pediatrics)
Plasma proteomic evidence for increased β-amyloid pathology after SARS-CoV-2 infection (Nature Medicine)
Letters read on TWiV 1190
Dr. Griffin’s COVID treatment summary (pdf)
Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

TWiV 1189: Viruses making waves Feb 02, 2025

TWiV notes the HHS communication pause, and describes research showing that rotavirus viroporin activity is necessary for intracellular calcium signals that contribute to viral pathogenesis, and control of human orthrflavivirus vaccine challenge by T cells in the absence of neutralizing antibodies.

Hosts: Vincent Racaniello, Alan Dove, Kathy Spindler, and Brianne Barker

Subscribe (free): Apple Podcasts, RSS, email

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Links for this episode

Support science education at MicrobeTV
ASV 2025
Rotavirus viroporin activity, calcium waves, and pathogenesis (Sci Adv)
T cells control human orthoflavivirus challenge (Nat Micro)
Letters read on TWiV 1189
Timestamps by Jolene Ramsey. Thanks!

Weekly Picks

Brianne – The Perfect Cacio e Pepe Recipe, According to Science (primary article here) Kathy – Dragonflies Loop-the-Loop Alan – My Beloved Monster, by Caleb Carr Vincent – Why Did the FDA Ban Red Dye #3

Listener Picks

Anne – Japan’s 65-Foot Towering Snow Walls

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1188: Clinical update with Dr. Daniel Griffin Feb 01, 2025

In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss changes in access to public health information, the Marburg and Ebola outbreaks in Africa, the largest tuberculosis outbreak in the US ever, the politicization of polio vaccine campaigns in Pakistan, effect of high pathogenic influenza in animals and on the economy before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, where to find PEMGARDA, provides information for Columbia University Irving Medical Center’s long COVID treatment center, where to go for answers to your long COVID questions, trials and devices to relieve some neurological complications of long COVID and the ramifications of long COVID in children, healthcare workers and adults.

Subscribe (free): Apple Podcasts, RSS, email

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Links for this episode

No morbidity and mortality in the US this week? (NPR)
More support for Marburg outbreak in Tanzania (Reliefweb)
Tanzania confirming second Marburg case (CIDRAP)
Norovirus mRNA vaccine …..hmmmm? (moderna)
What is noronvirus? (modernatx)
Largest tuberculosis outbreak ever in the US (Reuters)
Ebola outbreak in DRC during US:WHO strain (STAT News)
Uganda Ebola outbreak…..1 dead (Reuters)
Polio outside endemic zone due to militants? (Washington Post)
Mpox vaccination initiation in central Africa (CIDRAP)
Preparing rapid response to emerging infectious disease in Africa (PANTHER Health)
Mpox therapeutic study MOSA enrollment begins (Africa CDC)
Halting of US foreign aid for health programs…..not in the US best interests? (NY Times)
No PEPFAR (NY Times)
PEPFAR (US Department of State)
PEPFAR…..still not America first? Really? (CIDRAP)
Resurgence of infections globally may affect US…..what is global health? (NY Times)
Milk testing for H5N1….but I thought raw milk was the only healthy milk? (USDA)
How do you like your $10.99 dozen of eggs? (NY Times)
Farm outbreak of H5N1 (AP News)
US- high pathogenicity avian influenza viruses (World Organization for Animal Health)
H5N9 high pathogenic flu in duck farm California (CIDRAP)
More egg issues (CIDRAP)
Waste water scan for 11 pathogens (WastewaterSCan)
US respiratory virus activity (CDC Respiratory Illnesses)
Weekly surveillance report: cliff notes (CDC FluView)
RSV: Waste water scan for 11 pathogens (WastewaterSCan)
RSV-Network (CDC Respiratory Syncytial virus Infection)
US respiratory virus activity (CDC Respiratory Illnesses)
Respiratory syncytial virus vaccine effectiveness among US veterans, September, 2023 to March, 2024 (LANCET Infectious Diseases)
Waste water scan for 11 pathogens (WastewaterSCan)
COVID-19 deaths (CDC)
COVID-19 national and regional trends (CDC)
COVID-19 variant tracker (CDC)
SARS-CoV-2 genomes galore (Nextstrain)
Where to get pemgarda (Pemgarda)
EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
Fusion center near you….if in NY (Prime Fusions)
CDC Quarantine guidelines (CDC)
NIH COVID-19 treatment guidelines (NIH)
Infectious Disease Society guidelines for treatment and management (ID Society)
Drug interaction checker (University of Liverpool)
Molnupiravir safety and efficacy (JMV)
Convalescent plasma recommendation for immunocompromised (ID Society)
What to do when sick with a respiratory virus (CDC)
When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)
Managing healthcare staffing shortages (CDC)
Steroids, dexamethasone at the right time (OFID)
Anticoagulation guidelines (hematology.org)
Daniel Griffin’s evidence based medical practices for long COVID (OFID)
Long COVID hotline (Columbia : Columbia University Irving Medical Center)
The answers: Long COVID
Long COVID Recovery Program with Zara Dureno, BA, MOT
The current and future burden of long COVID in the United States (JID)
Transcutaneous vagus nerve stimulation improves Long COVID symptoms in a female cohort (Frontiers in Neurology)
Transcutaneous vagus nerve stimulation trials: https://www.mountsinai.org/clinical-trials/tvns-in-long-covid-19 https://www.centerwatch.com/clinical-trials/listings/NCT06585254/tvns-in-long-covid-19 Devices: https://pulsetto.tech/products/meet-pulsetto?pulsetto_offer_id=57&transaction_id=1024e5a0258b6647e262ba8fec5d62 https://www.dolphinmps.com/product/dolphin-neurostim-professional-single-kit-vagal-stim-kit/
Distinct pro-inflammatory/pro-angiogenetic signatures distinguish children with Long COVID from controls (Pediatric Research)
Persistent symptoms and clinical findings in adults with post-acute sequelae of COVID-19/post-COVID-19 syndrome in the second year after acute infection(PLoS Medicine)
SARS-COV-2 re-infection and incidence of post-acute sequelae of COVID-19 (PASC) among essential workers in New York (LANCET: Regional Health Americas)
Impact of COVID-19 Pandemic on the incidence and prevalence of postural orthostatic tachycardia syndrome (EHJ-QCCO European Heart Journal-Quality of Care & Clinical Outcomes)
Letters read on TWiV 1188
Dr. Griffin’s COVID treatment summary (pdf)
Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

TWiV 1187: The tau of herpesvirus Jan 26, 2025

TWiV explains a new blood test for head and neck cancer, Japanese regulators approve tecovirimat for mpox, an entry receptor for enterovirus D68, and anti-herpetic tau preserves neurons via a DNA sensing pathway in Alzheimer’s disease.

Hosts: Vincent Racaniello, Alan Dove, Kathy Spindler, Brianne Barker, and Angela Mingarelli

Subscribe (free): Apple Podcasts, RSS, email

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Links for this episode

Support science education at MicrobeTV
ASV 2025
Entry receptor for EV-D68 (Cell Host Microbe)
Anti-herpetic tau preserves neurons in Alzheimers (Cell Rep)
Letters read on TWiV 1187
Timestamps by Jolene Ramsey. Thanks!

Weekly Picks

Angela – Good genes are nice, but joy is better Brianne – Beaker Hair Clip Kathy – Pareidolia explained by street artist David Zinn TEDx talkAlso visit zinnart.com Alan – Screwworm is coming back in the Americas Vincent – Dr. Jay Bhattacharya Was Nice to Someone During a Debate. That Doesn’t Erase the Consequences of His Misinformation

Listener Picks

Sarah – The Extremophile Campaign: In Your Home (ECIYH) citizen science

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1186: Clinical update with Dr. Daniel Griffin Jan 25, 2025

In his weekly clinical update, Dr. Griffin and co-host Vincent Racaniello lament about the public changes from withdrawing from the WHO to health and scientific communication pauses by the Trump Administration after a brief discussion of Marburg in Tanzania and mpox in England before reviewing cats and bird flu, the recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, where to find PEMGARDA, provides information for Columbia University Irving Medical Center’s long COVID treatment center, and where to go for answers to your long COVID questions.

Subscribe (free): Apple Podcasts, RSS, email

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Links for this episode

Tanzania confirms Marburg virus outbreak (Reuters)
Clade Ib mpox in England (Reuters)
Withdrawing from the World Health Organization (WhiteHouse)
Fees costs behind withdrawing from WHO ….is that what we are suppose to believe? (Sky News)
Sorry to see you go, US? (WHO)
Where are the updates? (CDC Health Alert Network)
Pause in health communications of all kind (Washington Post)
NIH chaos…..streaming to a halt? (STAT News)
Devastation at the NIH, hiring traveling, meetings, communications(Science)
Protect your cat from bird flu (NPR)
No communication and cats with bird flu….does not sound good (CIDRAP)
Waste water scan for 11 pathogens (WastewaterSCan)
US respiratory virus activity (CDC Respiratory Illnesses)
Weekly surveillance report: clift notes (CDC FluView)
Baloxavir marboxil for prophylatix against influenza(NEJM)
Comparative effectiveness of baloxavir marboxil and oseltamir treatment for reducint household transmission of influenza (Influenza and other respiratory viruses)
RSV: Waste water scan for 11 pathogens (WastewaterSCan)
RSV-Network (CDC Respiratory Syncytial virus Infection)
US respiratory virus activity (CDC Respiratory Illnesses)
Waste water scan for 11 pathogens (WastewaterSCan)
COVID-19 deaths (CDC)
COVID-19 national and regional trends (CDC)
Host-microbe multiomic profiling identifies distinct COVD-19 immune dysregulation in solid organ transplant recipients (Nature Communications)
COVID-19 variant tracker (CDC)
SARS-CoV-2 genomes galore (Nextstrain)
Where to get pemgarda (Pemgarda)
EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
Fusion center near you….if in NY (Prime Fusions)
CDC Quarantine guidelines (CDC)
NIH COVID-19 treatment guidelines (NIH)
Infectious Disease Society guidelines for treatment and management (ID Society)
Drug interaction checker (University of Liverpool)
Real‐world effectiveness and safety of oral azvudine versus nirmatrelvir‒ritonavir (Paxlovid) in hospitalized patients with COVID-19 (Signal Transduction and Targeted Therapy)
Molnupiravir safety and efficacy (JMV)
Convalescent plasma recommendation for immunocompromised (ID Society)
What to do when sick with a respiratory virus (CDC)
When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)
Managing healthcare staffing shortages (CDC)
Steroids, dexamethasone at the right time (OFID)
Anticoagulation guidelines (hematology.org)
Daniel Griffin’s evidence based medical practices for long COVID (OFID)
Long COVID hotline (Columbia : Columbia University Irving Medical Center)
The answers: Long COVID
Long COVID Recovery Program with Zara Dureno, BA, MOT
Letters read on TWiV 1186
Dr. Griffin’s COVID treatment summary (pdf)
Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

TWiV 1185: The birds and the Bs Jan 19, 2025

TWiV explains Guillain-Barré Syndrome associated with RSV vaccines, outbreaks of metapneumovirus in China and India, editors resign to protest Elsevier’s use of AI in publishing, global distribution and diversity of wild bird associated pathogens, and broadly inhibitory anti-neuraminidase antibody from human memory B cells.

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Brianne Barker

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Links for this episode

Support science education at MicrobeTV
ASV 2025
GBS with RSV vaccine (FDA)
Increase in respiratory infections in China (ECDC)
Elsevier journal editors resign (Retract Watch)
Wild bird associated pathogens (Med)
Broad anti-neuraminidase antibody (Cell Host Micr)
Letters read on TWiV 1185
Timestamps by Jolene. Thanks!

Weekly Picks

Brianne – Dear Reviewer 2 Rich – National Data Buoy Center Alan – BBC audio program on the World Morse Code Championships Vincent – These are the 20 most-studied bacteria — the majority have been ignored

Listener Picks

Peter – Local graffiti in Sydney Vivian – The Peoples’ Hospital by Dr. Ricardo Nuila

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1184: Clinical update with Dr. Daniel Griffin Jan 18, 2025

In his weekly clinical update, Dr. Griffin discusses current and past outbreaks of “vaccine” preventable diseases including whooping cough, polio and measles with your co-host Vincent Racaniello and the recent increase in norovirus outbreaks, if alcohol-based hand sanitizers aid in the spread of norovirus before reviewing the recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, where to find PEMGARDA, provides information for Columbia University Irving Medical Center’s long COVID treatment center, if “long COVID” like symptoms occurs after influenza and how long COVID may associate with neurological complicates that control verbal memory.

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Links for this episode

Notable infectious diseases in US (CDC NNDSS)
Get your Tdap: whooping cough case increase (California Department of Public Health)
Resurgence of measles among preschool aged children 1989-1991 (CDC: MMWR)
Adults vulnerable to ‘childhood’ diseases (NY Times)
Pivotal decision that led to a resurgence of polio (NY Times)
Can polio return due to lagging vaccination? (NY Times)
NoroSTAT Data Table (CDC Norovirus)
The discovery of the 27-nm Norwalk virus: an historic perspective (JID)
Why the “Ferrari of viruses” is surging through the northern hemisphere (Science)
Waste water scan for 11 pathogens (WastewaterSCan)
Norovirus at Chipotle, $25million food fine (NY Times)
Chipotle food issues: 2015 settlement with the justice department (Chipotle News)
Purcel anyone? Hand sanitizers increase norovirus risk? (Canadian Medical Association Journal)
Visualization by immune electron microscopy of a 27nm particle associated with acute infectious nonbacterial gastroenteritis (Journal of Virology)
Winter vomiting disease (JID)
ACIP: expanded recommendations for pneumococcal conjugate vaccines(CDC: MMWR)
Presumptive bird flu case in San Francisco (SF. Gov)
Waste water scan for 11 pathogens (WastewaterSCan)
US respiratory virus activity (CDC Respiratory Illnesses)
Weekly surveillance report: cliff notes (CDC FluView)
Antiviral medications for treatment ofnonsevere influenza(JAMA Network: JAMA Internal Medicine)
Xofluza (GoodRx)
RSV: Waste water scan for 11 pathogens (WastewaterSCan)
RSV-Network (CDC Respiratory Syncytial virus Infection)
US respiratory virus activity (CDC Respiratory Illnesses)
Waste water scan for 11 pathogens (WastewaterSCan)
COVID-19 deaths (CDC)
COVID-19 national and regional trends (CDC)
COVID-19 variant tracker (CDC)
SARS-CoV-2 genomes galore (Nextstrain)
Where to get pemgarda (Pemgarda)
EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
Fusion center near you….if in NY (Prime Fusions)
CDC Quarantine guidelines (CDC)
NIH COVID-19 treatment guidelines (NIH)
Infectious Disease Society guidelines for treatment and management (ID Society)
Drug interaction checker (University of Liverpool)
Molnupiravir safety and efficacy (JMV)
Convalescent plasma recommendation for immunocompromised (ID Society)
What to do when sick with a respiratory virus (CDC)
When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)
Managing healthcare staffing shortages (CDC)
Steroids, dexamethasone at the right time (OFID)
Anticoagulation guidelines (hematology.org)
Daniel Griffin’s evidence based medical practices for long COVID (OFID)
Long COVID hotline (Columbia : Columbia University Irving Medical Center)
Symptom evolution in individuals with ongoing symptomatic COVID-19 and post COVID-19 syndrome after SARS-CoV-2 vaccination versus influenza vccination (Journal of Infection) Neurological post-COVID syndrome is associated with substantial impairment of verbal short-term and working memory (Scientific Reports)
Letters read on TWiV 1184
Dr. Griffin’s COVID treatment summary (pdf)
Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

TWiV 1183: More than 2024 viruses Jan 12, 2025

TWiV reviews some of their favorite virology stories from 2024.

Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Brianne Barker

Subscribe (free): Apple Podcasts, RSS, email

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Links for this episode

Support science education at MicrobeTV
ASV 2025
SARS-CoV-2 origins (TWiV Special)
TWiV 1163: Hepadnaviridae in the heartland
TWiV 1117 Pol dances with the RNA that brought it
HPV vaccine success (TWiV 1083, 1151, 1159, 1173)
Monkeypox (TWiV 1095, 1119, 1143, 1145, 1147)
Influenza H5N1 virus (VTWiV 1113, TWiV 1131, TWiV 1173)
Influenza B/Yamagata removed from vaccine (TWiV 1161)
Fiasco of poliomylelitis eradication (TWiV 1091, TWiV 1125, TWiV 1105, TWiV 1151, TWiV 1145, TWiV 1147, TWiV 1161, TWiV 1143)
Protective immunity isn’t just bout antibodies (TWiV 1089, 1105, 1115, 1135, 1165)
Closing the toilet lid doesn’t help (TWiV 1083)
Timestamps by Jolene. Thanks!

Weekly Picks

Brianne – Scientists put vampire bats on treadmills to learn about metabolism Kathy – Says Who?: A Kinder, Funner, Usage Guide for Everyone Who Cares About Words Rich – Mark Rober on PBS Newshour Brief But Spectacular (Wiki; Testing The World’s Smartest Crow) Vincent – How Glenn Gould Broke Classical Music

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1182: Clinical update with Dr. Daniel Griffin Jan 11, 2025

In his weekly clinical update, Dr. Griffin discusses how vaccination and vaccine hesitancy affects public health and disease spread in terms of mpox, the first human death from H5N1 in US, why one should not feed their pets raw pet food and the metapneumonia outbreak in China before reviewing the recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, where to find PEMGARDA, how nirmatrelvir-ritonavir/Paxlovid reduces adverse outcomes of COVID in patients with kidney disease, provides information for Columbia University Irving Medical Center’s long COVID treatment center, SARS-CoV-2 infection affects skin conditions including shingles and if long antiviral treatment affects long COVID.

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Links for this episode

Mpox vaccination hesitancy, previous immunisation coverage, and vaccination readiness in the African region (eClincial Medicine)
Global prevalence and correlates of mpox vaccine acceptance and uptake (Communications Medicine)
First case of new mpox variant in France (Reuters)
First “Bird flu” death in US (NY Times)
Emerging threat of H5N1 to human health (NEJM)
Don’t feed your pets raw food (County of Los Angeles Public Health)
Oregon, nationwide raw pet food recall (CIRAP)
Raw cat food avian flu, is this like raw milk? (CIDRAP)
Human metapneumovirus surging in China (The Guardian)
Viral video of viral chaos: human metapneumovirus in Chinese hospital (The Economic Times)
Human metapneumovirus in China (NY Times)
Acute respiratory infections including human metapneumovirus in northern hemisphere (WHO)
Waste water scan for 11 pathogens (WastewaterSCan)
US respiratory virus activity (CDC Respiratory Illnesses)
Weekly surveillance report: clift notes (CDC FluView)
RSV: Waste water scan for 11 pathogens (WastewaterSCan)
RSV-Network (CDC Respiratory Syncytial virus Infection)
US respiratory virus activity (CDC Respiratory Illnesses)
Waste water scan for 11 pathogens (WastewaterSCan)
COVID-19 deaths (CDC)
COVID-19 national and regional trends (CDC)
COVID-19 variant tracker (CDC)
SARS-CoV-2 genomes galore (Nextstrain)
Where to get pemgarda (Pemgarda)
EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
Fusion center near you….if in NY (Prime Fusions)
CDC Quarantine guidelines (CDC)
NIH COVID-19 treatment guidelines (NIH)
Infectious Disease Society guidelines for treatment and management (ID Society)
Drug interaction checker (University of Liverpool)
The effect of nirmatrelvir-ritonavir on short- and long-term adverse outcomes from COVID-19 among patients with kidney disease (OFID)
Paxlovid tied to lower risk of hospital stay, heart problems, death in adults with kidney disease and COVID (CIDRAP)
Molnupiravir safety and efficacy (JMV)
Convalescent plasma recommendation for immunocompromised (ID Society)
What to do when sick with a respiratory virus (CDC)
When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)
Managing healthcare staffing shortages (CDC)
Steroids, dexamethasone at the right time (OFID)
Anticoagulation guidelines (hematology.org)
Daniel Griffin’s evidence based medical practices for long COVID (OFID)
Long COVID hotline (Columbia : Columbia University Irving Medical Center)
Chronic urticaria, vitiligo, alopecia areata, and herpes zoster following COVID-19 infection (Journal of Dermatology)
Impact of extended-course oral nirmatrelvir/ritonavir in established Long COVID:
(Communications Medicine)
Letters read on TWiV 1182
Dr. Griffin’s COVID treatment summary (pdf)
Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

TWiV 1181: Seek and ye shall find, coronaviruses and phage Jan 05, 2025

TWiV discusses an outbreak of influenza H5N1 that killed over half of the great cats at a Washington sanctuary, origin and cross-species transmission of bat coronaviruses in China, and the diverse and abundant phages that enter cells via receptors encoded on conjugative plasmids.

Hosts: Vincent Racaniello, Rich Condit, and Jolene Ramsey

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

Links for this episode

Support science education at MicrobeTV
ASV 2025
H5N1 virus kills great cats at Washington sanctuary (CNN)
Macroevolution of bat coronaviruses in China (Nat Comm)
EcoHealth Alliance funding suspended (Science)
Conjugative plasmids support diverse and abundant phages (Nat Comm)
Letters read on TWiV 1181
Timestamps by Jolene. Thanks!

Weekly Picks

Rich – Pareidolia (wiki) Jolene – Pathways to Science database Vincent – Wendy Carlos and Switched-On Bach

Listener Picks

Arjan – Gutsick Gibbon’s YouTube channel Alan – 2024 Nobel Prize Lectures in Chemistry

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1180: Clinical update with Dr. Daniel Griffin Jan 04, 2025

In his weekly clinical update, Dr. Griffin discusses the recent increase in norovirus outbreaks, human cases of H5N1 avian influenza, before reviewing the recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, where to find PEMGARDA, how effective Molnupiravir is and provides information for Columbia University Irving Medical Center’s long COVID treatment center.

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

Links for this episode

Norovirus: Waste water scan for 11 pathogens (WastewaterSCan)
Adolescent with Influenza A H5N1 infection (NEJM)
Highly pathogenic avian Influenza A ( H5N1) virus infections in humans (NEJM)
Emerging threat of H5N1 to human health (NEJM)
US respiratory virus activity (CDC Respiratory Illnesses)
In-hospital outcomes of healthcare-associated Coronavirus Disease 2019 (Omicron) versus healthcare-associated Influenza (CID)
Waste water scan for 11 pathogens (WastewaterSCan)
US respiratory virus activity (CDC Respiratory Illnesses)
Weekly surveillance report: cliff notes (CDC FluView)
RSV: Waste water scan for 11 pathogens (WastewaterSCan)
RSV-Network (CDC Respiratory Syncytial virus Infection)
US respiratory virus activity (CDC Respiratory Illnesses)
Waste water scan for 11 pathogens (WastewaterSCan)
COVID-19 deaths (CDC)
COVID-19 national and regional trends (CDC)
COVID-19 variant tracker (CDC)
SARS-CoV-2 genomes galore (Nextstrain)
Where to get pemgarda (Pemgarda)
EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
Fusion center near you….if in NY (Prime Fusions)
CDC Quarantine guidelines (CDC)
NIH COVID-19 treatment guidelines (NIH)
Infectious Disease Society guidelines for treatment and management (ID Society)
Drug interaction checker (University of Liverpool)
Molnupiravir safety and efficacy (JMV)
Real clinical effectiveness of Molnupiravir against 30-day mortality (OFID)
Convalescent plasma recommendation for immunocompromised (ID Society)
What to do when sick with a respiratory virus (CDC)
When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)
Managing healthcare staffing shortages (CDC)
Steroids, dexamethasone at the right time (OFID)
Anticoagulation guidelines (hematology.org)
Daniel Griffin’s evidence based medical practices for long COVID (OFID)
Long COVID hotline (Columbia : Columbia University Irving Medical Center)Post-COVID Condition Risk Factors and Symptom Clusters and Associations with Return to Pre-COVID Health (CID)
Letters read on TWiV 1180
Dr. Griffin’s COVID treatment summary (pdf)
Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

TWiV 1179: Dark matter and warning signs Dec 29, 2024

TWiV reviews RFK Jr’s demand to revoke polio vaccine, Wuhan lab samples do not include close relatives to SARS-CoV-2, using artificial intelligence to discover the RNA virosphere, and biomarkers that discriminate early and late phases of respiratory virus infections from a SARS-CoV-2 human challenge study.

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, Kathy Spindler, and Angela Mingarelli

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

Links for this episode

Support science education at MicrobeTV
ASV 2025
RFK Jr lawyer wants revocation of polio vaccine (CNN)
Wuhan lab has no samples close to SARS-CoV-2 (Nature)
Using AI to discover RNA virosphere (Cell)
SARS-CoV-2 human challenge reveals biomarkers (Nat Comm)
Does this challenge study pass the smell test? (TWiV 863)
Letters read on TWiV 1179
Timestamps by Jolene. Thanks!

Weekly Picks

Angela – Science’s 2024 breakthrough of the year, Lenacapavir “the long shot”. NEJM papers with Lenacapavir trials: one and two. Kathy – Bach Toccatta and Fugue on floor piano Rich – Never Cry Wolf Vincent – Common Raven and American Crow

Listener Pick

Jaan – Meute (one, two, three)

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

TWiV 1178: Clinical update with Dr. Daniel Griffin Dec 28, 2024

In his weekly clinical update, Dr. Griffin deep dives into the whooping cough epidemic and bird flu in big cats, and in conjunction with your host Vincent Racaniello discusses the recent case of paralytic poliomyelitis in Israel, measles outbreaks and HHS campaign for vaccine safety campaign before reviewing the recent statistics on SARS-CoV-2 infection, the WasterwaterScan dashboard, if the COVID mRNA vaccine is effective against symptomatic SARS-CoV-2 infection and hospitalization in children, where to find PEMGARDA, information for Columbia University Irving Medical Center’s long COVID treatment center, how long COVID effects one’s activities, personality and neuropsychiatric symptoms.

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

Links for this episode

Highest level of whooping cough cases in a decade (NBC News)
Provisional pertussis surveillance report (CDC)
Polio moves into Israel (Jerusalem Post)
Polio today (GPEI)
Measles- the let’s get real vaccination campaign (CDC)
Measles fact sheet (CDC)
Measles- near you (CDC)
Let’s get real about childhood vaccines (HHS)
The FACTS about childhood vaccines (HHS)
Tigers and cougars dying from bird flu, oh my! (NY Times)
US respiratory virus activity (CDC Respiratory Illnesses)
Waste water scan for 11 pathogens (WastewaterSCan)
US respiratory virus activity (CDC Respiratory Illnesses)
Weekly surveillance report: cliff notes (CDC FluView)
Burden of all-cause mortality following Influenza-associated hospitalizations (CID)
Waste water scan for 11 pathogens (WastewaterSCan)
RSV-Network (CDC Respiratory Syncytial virus Infection)
COVID-19 deaths (CDC)
COVID-19 national and regional trends (CDC)
COVID-19 variant tracker (CDC)
SARS-CoV-2 genomes galore (Nextstrain)
Initial effectiveness of mRNA-1273 against SARS-CoV-2 infection and hospitalization in young children (OFID)
Where to get pemgarda (Pemgarda)
EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
Fusion center near you….if in NY (Prime Fusions)
CDC Quarantine guidelines (CDC)
NIH COVID-19 treatment guidelines (NIH)
Infectious Disease Society guidelines for treatment and management (ID Society)
Drug interaction checker (University of Liverpool)
Molnupiravir safety and efficacy (JMV)
Convalescent plasma recommendation for immunocompromised (ID Society)
What to do when sick with a respiratory virus (CDC)
When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)
Managing healthcare staffing shortages (CDC)
Steroids, dexamethasone at the right time (OFID)
Anticoagulation guidelines (hematology.org)
Daniel Griffin’s evidence based medical practices for long COVID (OFID)
Long COVID hotline (Columbia : Columbia University Irving Medical Center)
Long COVID and significant long COVID–associated activity limitation among adults
(CDC: MMWR)
2024 Update of the RECOVER-Adult Long COVID Research Index (JAMA Network)
About 8% of US adults have ever had long COVID, survey finds(CIDRAP)
Real-world effectiveness and causal mediation study of BNT162b2 on long COVID risks in children and adolescents (eClinicalMedicine)
Personality and neuropsychiatric symptoms in individuals diagnosed with long COVID(BMC Infectious Diseases)Post-COVID Condition Risk Factors and Symptom Clusters and Associations with Return to Pre-COVID Health (CID)
Letters read on TWiV 1178 38:11
Dr. Griffin’s COVID treatment summary (pdf)
Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

TWiV 1177: Going to school for flu Dec 22, 2024

At the School for Influenza in Brisbane, TWiV speaks with Kirsty, Erik and Rebecca about their careers and their research.

Host: Vincent Racaniello

Guests: Kirsty Short, Erik Karlsson, and Rebecca Cox

Subscribe (free): Apple Podcasts, RSS, email

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Links for this episode

Support science education at MicrobeTV
Diabetes, obesity, and COVID-19 severity (Diab Care)
Rice farming and zoonosis in Cambodia (One Health)
Influenza correlates of protection (mBio)
Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1176: Clinical update with Dr. Daniel Griffin Dec 21, 2024

In his weekly clinical update, Dr. Griffin continues his discussion of whether the mysterious respiratory illness in the Congo is malaria, and in conjunction with your host Vincent Racaniello discusses how routine childhood immunizations especially that against poliovirus are threatened by Robert F Kennedy Jr and Aaron Siri, the origin of the SAR-CoV-2 virus and retraction of Didier Raoult’s research, then returns to discussing the first case of severe disease following H5N1 infection in humans and the state of California’s “bird flu emergency”, the benefit of the measles vaccine, before reviewing the recent statistics on SARS-CoV-2 infection, the WasterwaterScan dashboard, how vaccination reduced hospitalization of children between 5-17 years, the ACIP recommendation for the immunocompromised, where to find PEMGARDA, information for Columbia Unversity Irving Medical Center’s long COVID treatment center, long COVID in cancer patients and the physical malaises of long COVID.

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

Links for this episode

Mystery disease in DRC kills mostly children (ALJAZEERA)
Malaria—mysterious disease in DRC? (ALJAZEERA)
Mysterious disease in DRC is severe malaria (ALJAZEERA)
Confirmed first severe human H5N1 case (CIDRAP)
California declares bird flu emergency (Reuters)
RFK’s lawyer asks FDA to revoke approval of the polio vaccine (NY Times)
NO WAY! Vaccination promotes survival and health? (LANCET)
10.6 million cases of measles this year alone! (WHO)
20% rise in measles…..(NY Times)
No Sars-CoV-2 relatives in Shi Zhengli’s freezers (Nature)
Controversial COVID study that promoted unproven treatment retracted after four-year saga (Nature)
Influenza weekly surveillance report: clift notes (CDC FluView)
Waste water scan for 11 pathogens (WastewaterSCan)
RSV-Network (CDC Respiratory Syncytial virus Infection)
US respiratory virus activity (CDC Respiratory Illnesses)
COVID-19 deaths (CDC)
COVID-19 national and regional trends (CDC)
Waste water scan for 11 pathogens (WastewaterSCan)
COVID-19 variant tracker (CDC)
SARS-CoV-2 genomes galore (Nextstrain)
BNT162b2 XBB Vaccine for COVID-19 Among Children 5-17 Years ofAge (JAMA Network)
ACIP recommendations for those over 65 years and those under 6 months who are immunocompromised (CDC MMWR)
Where to get pemgarda (Pemgarda)
EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
Fusion center near you….if in NY (Prime Fusions)
CDC Quarantine guidelines (CDC)
NIH COVID-19 treatment guidelines (NIH)
Infectious Disease Society guidelines for treatment and management (ID Society)
Drug interaction checker (University of Liverpool)
Molnupiravir safety and efficacy (JMV)
Convalescent plasma recommendation for immunocompromised (ID Society)
What to do when sick with a respiratory virus (CDC)
When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)
Managing healthcare staffing shortages (CDC)
Steroids, dexamethasone at the right time (OFID)
Anticoagulation guidelines (hematology.org)
Daniel Griffin’s evidence based medical practices for long COVID (OFID)
Long COVID hotline (Columbia : Columbia University Irving Medical Center)
Post-acute sequelae of COVID-19 in cancer patients: Two cohorts in UK and Hong Kong(Cancer Medicine)
Skeletal muscle adaptations and post-exertional malaise in long COVID (Cell: Trends in Endocrinology & Metabolism)
Letters read on TWiV 1176
Dr. Griffin’s COVID treatment summary (pdf)
Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

TWiV 1175: A hitchiker's guide to virology Dec 15, 2024

TWiV reviews the appearance of poliovirus in Europe, mystery disease in DRC, global burden of Chikungunya, viruses of parasitic nematodes that induce antibody responses in vertebrate hosts, and picobirnaviruses, do they infect eukaryotes or prokaryotes?

Hosts: Vincent Racaniello, Alan Dove, and Jolene Ramsey

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

Links for this episode

ASV 2025
Write your senators about RFK Jr
Support science education at MicrobeTV
Poliovirus in Europe (WHO)
DRC mystery disease (Reuters)
Global burden of chikungunya (BMJ Global Health)
RNA viruses of parasitic nematodes (Nat Micro)
Picobirnaviruses encode bacterial lysins (PNAS)
Prokaryotic ribosome binding site in picobirnavirus genome (Virology)
Letters read on TWiV 1175
Timestamps by Jolene. Thanks!

Weekly Picks

Alan – Sondehub and radiosonde hunting Jolene – Book “10 to 25: The Science of Motivating Young People” By David Yeager Vincent – Dr. Vinay Prasad “Sabotaging RFK Jr’s Confirmation Will Increase Vaccine Hesitancy” & “Doctors Criticizing RFK Jr. Paved the Way for His Ascendancy”

Listener Picks

Syl – Foldscope Jennifer – minutiae

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1174: Clinical update with Dr. Daniel Griffin Dec 14, 2024

In his weekly clinical update, Dr. Griffin deep dives into whether the mysterious respiratory illness in the Congo is malaria, and in conjunction with your host Vincent Racaniello discusses the failure of the poliovirus eradication campaign with virus circulation detected throughout Europe and how we should focus on disease control not virus circulation, then returns to discussing avian influenza in raw milk and the early stoppage of the mpox antiviral Tecovirimat before reviewing the recent statistics on SARS-CoV-2 infection, the WasterwaterScan dashboard, if there is a difference in protection against the development of severe disease between an mRNA or a protein based vaccine, where to find PEMGARDA, and information for Columbia Unversity Irving Medical Center’s long COVID treatment center.

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

Links for this episode

IIs the mysterious disease in the Congo, malaria? (AP News)
State of global health, year-end remarks by WHO director-general (WHO)
Really, progress towards poliomyelitis eradication? (CDC MMWR)
Increases in confirm cases ¹ control of poliomyelitis (WHO)
Polio European Union and United Kingdom, is that 1 global entry? (Science)
Is the WHO the global CDC? polio vaccination guidelines (WHO)
Do you feed your cats raw milk? (Public Health LA county)
Is there avian influenza in the zoo near you? (Maricopa)
Don’t feed your cat raw milk (CIDRAP)
Holy Cow! H5N1 in cows! (microbeTV)
Tecovirimat no improvement in Mpox resolution or pain(NIAID NIH)
Interim results from STOMP study of Tecovirimat (SIGA)
Trial stops enrollment after Tpoxx fails (CIDRAP)
Is Tecovirimat really first-in-class mpox therapy? (Viruses)
Influenza weekly surveillance report: clift notes (CDC FluView)
US respiratory virus activity (CDC Respiratory Illnesses)
Waste water scan for 11 pathogens (WastewaterSCan)
RSV-Network (CDC Respiratory Syncytial virus Infection)
COVID-19 deaths (CDC)
COVID-19 national and regional trends (CDC)
Waste water scan for 11 pathogens (WastewaterSCan)
COVID-19 variant tracker (CDC)
SARS-CoV-2 genomes galore (Nextstrain)
Relative effectiveness of homologous NVX-CoV2373 and BNT162b2 COVID-19 vaccinations in South Korea (Vaccine)
Phase III trial results! Comparative efficacy and safety of COVID-19 (BMC Infectious Diseases)
Where to get pemgarda (Pemgarda)
EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
Fusion center near you….if in NY (Prime Fusions)
CDC Quarantine guidelines (CDC)
NIH COVID-19 treatment guidelines (NIH)
Infectious Disease Society guidelines for treatment and management (ID Society)
Drug interaction checker (University of Liverpool)
Molnupiravir safety and efficacy (JMV)
Convalescent plasma recommendation for immunocompromised (ID Society)
What to do when sick with a respiratory virus (CDC)
When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)
Managing healthcare staffing shortages (CDC)
Stop playing favorites with COVID-19 in healthcare settings (Infection Control & Hospital Epidemiology)
Steroids, dexamethasone at the right time (OFID)
Anticoagulation guidelines (hematology.org)
Remdesivir Effectiveness in Reducing the Risk of 30-day Readmission in Vulnerable Patients Hospitalized for COVID-19 (CID)
Daniel Griffin’s evidence based medical practices for long COVID (OFID)
Long COVID hotline (Columbia : Columbia University Irving Medical Center)
Letters read on TWiV 1174
Dr. Griffin’s COVID treatment summary (pdf)
Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

TWiV 1173: Holy Cow! Convergent evolution! Dec 08, 2024

TWiV reviews nominees to head NIH, FDA, and CDC, cervical cancer decline following HPV vaccination, local dengue in Texas, human isolate of H5N1 virus is transmissible and virulent in animal models, and shared mechanisms of immune evasion among animal and bacterial viruses.

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, Kathy Spindler, Brianne Barker, and Jolene Ramsey

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

Links for this episode

Bhattacharya nominated to head NIH (Science)
Makary nominated to head FDA (Science)
Weldon nominated to head CDC (Chief Healthcare Exec)
Cervical cancer declining following vaccination (JAMA Net)
Local dengue case in Texas (Texas HHS)
H5N1 human isolate transmissible and virulent (Nature)
H5 current situation (CDC)
Global H5N1 cases (Our World in Data)
Conserved immune evasion in animal and bacterial viruses (Cell)
Timestamps by Jolene. Thanks!

Weekly Picks

Brianne – Pale Blue Pod Kathy – PhysicsGirl recent Instagram post, ScienceAdvisor signup free daily sci news distillation, Semi-conducting hydrogels, Bot that can pick up things with a soft touch, “Pigeonbot II”, a drone called LisRaptor, zapping forever chemicals like PFAS with light and here Rich – Vendee Globe Jolene – Center for the Improvement of Mentored Research Experiences Vincent – These two ancient human relatives crossed paths 1.5 million years ago

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1172: Clinical update with Dr. Daniel Griffin Dec 07, 2024

In his weekly clinical update, Dr. Griffin summarizes influenza and RSV circulation in the US, the benefit of administering oseltamivir early and if influenza vaccination reduces secondary household infections, before reviewing the recent statistics on SARS-CoV-2 infection, the WasterwaterScan dashboard, how 1st or 2nd trimester SARS-CoV-2 infections may shorten newborn telomeres, what are B1 cells, if IgG4 responses are critical for protection elicited by mRNA vaccines, if there is a difference in protection against the development of severe disease between an mRNA or a protein based vaccine, where to find PEMGARDA, if remdesivir reduces readmission of vulnerable patients once hospitalized for COVID-19, information for Columbia University Irving Medical Center’s long COVID treatment center, if transcutaneous electrical nerve stimulation ameliorates musculoskeletal pain and fatigue during long COVID, do antihistamines reduce post-acute sequelae of SARS-CoV-2 infection and how long can SARS-CoV-2 antigens be detected in blood.

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

Links for this episode

Influenza weekly surveillance report: cliff notes (CDC FluView)
US respiratory virus activity (CDC Respiratory Illnesses)
Influenza vaccines protect against secondary infections in households (JAMA Network)
Benefit of early oseltamivir therapy for influenza A (CID)
RSV-Network (CDC Respiratory Syncytial virus Infection)
COVID-19 deaths (CDC)
COVID-19 national and regional trends (CDC)
Waste water scan for 11 pathogens (WastewaterSCan)
COVID-19 variant tracker (CDC)
SARS-CoV-2 genomes galore (Nextstrain)
Maternal infection of SARS-CoV-2 during 1st and 2nd trimesters newborn telomere shortening (Journal of Translational Medicine)
What is a B1 cell? (Wikipedia)
Pre-COVID and post-COVID vaccination on long COVID (Journal of Infection)
Delayed Induction of Noninflammatory SARS-CoV-2 Spike-Specific IgG4 Antibodies after BNT162b2 Vaccination in Children (The Pediatric Infectious Disease Journal)
Relative effectiveness of homologous NVX-CoV2373 and BNT162b2 COVID-19 vaccinations in South Korea (Vaccine)
Phase III trial results! Comparative efficacy and safety of COVID-19 vaccines (BMC Infectious Diseases)
Where to get pemgarda (Pemgarda)
EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
Fusion center near you….if in NY (Prime Fusions)
CDC Quarantine guidelines (CDC)
NIH COVID-19 treatment guidelines (NIH)
Infectious Disease Society guidelines for treatment and management (ID Society)
Drug interaction checker (University of Liverpool)
Molnupiravir safety and efficacy (JMV)
Convalescent plasma recommendation for immunocompromised (ID Society)
What to do when sick with a respiratory virus (CDC)
When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)
Managing healthcare staffing shortages (CDC)
Steroids, dexamethasone at the right time (OFID)
Anticoagulation guidelines (hematology.org)
Remdesivir Effectiveness in Reducing the Risk of 30-day Readmission in Vulnerable Patients Hospitalized for COVID-19 (CID)
Daniel Griffin’s evidence based medical practices for long COVID (OFID)
Long COVID hotline (Columbia : Columbia University Irving Medical Center)
Transcutaneous electrical nerve stimulation for fibromyalgia-like syndrome in patients with Long-COVID(Scientific Reports)
Mitigating the risks of post-acute sequelae of SARS-CoV-2 infection (PASC) with intranasal chlorpheniramine (BMC Infectious Diseases)
Measurement of circulating viral antigens post-SARS-CoV-2 infection (CID)
Letters read on TWiV 1172
Dr. Griffin’s COVID treatment summary (pdf)
Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

TWiV 1171: The born immunity Dec 01, 2024

TWiV reviews susceptibility to vaccine-preventable infections in asylum seekers, the economic power of vaccines, French university tries to bury its investigation of a faculty member’s ethical lapses, transmission dynamics of SARS-CoV-2 in New Zealand before and after COVID-19, and a germ line encoded antibody that recognizes a broad array of enveloped viruses.

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Brianne Barker

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

Links for this episode

Why RFK Jr is not suitable for HHS (YouTube)
Write your Senators to oppose RFK Jr
Support MicrobeTV
ASV 2025
Susceptibility to infections in asylum seekers (NEJM)
RSV hospitalization in adults (JAMA Net Open)
Ethics failings at French university (Science)
RSV transmission in New Zealand (Nat Commun)
Glycan reactive IgM binds multiple viruses (SciImmunol)
Timestamps by Jolene. Thanks!

Weekly Picks

Brianne – Publication of Updated Human Cell Atlas Rich – Astroscale Alan – E3 ubiquitin ligase game, and an article about its origin Vincent – In the Quantum World, Even Points of View Are Uncertain

Listener Pick

Ryan – A Dangerous Moment

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1170: Clinical update with Dr. Daniel Griffin Nov 30, 2024

In his weekly clinical update, Dr. Griffin dives into H5N1/influenza and RSV circulation in the US, whether or not H5N1 is “adapting” for human-human transmission, why drinking raw milk may NOT be the best idea despite RFK Jr endorsement, before reviewing the recent statistics on SARS-CoV-2 infection, the WasterwaterScan dashboard, how if I encounter no one I can infect no one, the efficacy of COVID-19 boosters, how vaccines are the ‘seat belt’ of public health, the results of two PLACEBO control studies assessing antiviral therapy for COVID-19, where to find PEMGARDA, susceptibility of neurological complications in young to middle-aged adults and how discussing the origins of the pandemic and rise of scientific harassment will allow you to avoid a political conversation around your Thanksgiving day table, the interplay between transmission and immunity for virus spread and who to call if you do get sick this holiday. Happy Thanksgiving!

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

Links for this episode

Influenza weekly surveillance report: cliff notes (CDC FluView)
US respiratory virus activity (CDC Respiratory Illnesses)
RSV-Network (CDC Respiratory Syncytial virus Infection)
In case you missed, US respiratory virus activity (CDC Respiratory Illnesses)
Adaptation of H5N1 to humans…..sequence analysis (Nature)
Favoring human transmission for H5N1 ?(Youtube: medcram)
From 2022: unprecedented bird flu outbreaks sweeping the world…..and we are still talking about it? (Nature)
What children get flu: First child in US infected with H5N1 (CDC Newsroom)
Bird flu detected in raw milk……but RFK at HHS says it is safe? (NBC News)
COVID-19 deaths (CDC)
COVID-19 national and regional trends (CDC)
Waste water scan for 11 pathogens (WastewaterSCan)
COVID-19 variant tracker (CDC)
SARS-CoV-2 genomes galore (Nextstrain)
If I see no one in my house, household Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Transmission is reduced! (CID)
Updated boosters conferred protection against SARS-CoV-2 infection and emergency visits/hospitalizations during a JN.1 variant wave(CID)
Provisional COVID-19 mortality (CDC National Center for Health Statistics)
Influenza, RSV and COVID-19 vaccine in nursing home residents (CDC MMWR)
Vaccines are the seat belts of public health (TRID)
Where to get pemgarda (Pemgarda)
EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
Fusion center near you….if in NY (Prime Fusions)
CDC Quarantine guidelines (CDC)
NIH COVID-19 treatment guidelines (NIH)
Infectious Disease Society guidelines for treatment and management (ID Society)
Drug interaction checker (University of Liverpool)
Molnupiravir safety and efficacy (JMV)
Effectiveness of molnupiravir against 30-day mortality among 74 541 SARS-CoV-2 positive patients (OFID)
Sustained Recovery Among Outpatients With COVID-19 Receiving Montelukast vs Placebo(JAMA Network Open)
Convalescent plasma recommendation for immunocompromised (ID Society)
What to do when sick with a respiratory virus (CDC)
When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)
Managing healthcare staffing shortages (CDC)
Steroids, dexamethasone at the right time (OFID)
Anticoagulation guidelines (hematology.org)
Remdesivir for treatment of COVID-19 requiring oxygen support (CID)
Daniel Griffin’s evidence based medical practices for long COVID (OFID)
Neurologic manifestations of long COVID disproportionately affect young and middle-aged Adults (Annals on Neurology)
To review, three score and two months ago, the WHO brought for on this planet, the declaration of SARS-CoV-2/COVID-19….
How nature began a pandemic (microbeTV)
Bullying within the origin scientific discourse……by those at Rutgers (Science)
Scientific harassment on the rise (Science)
Doxing :The de-identified of the de-identified (Wikipedia)
Harassment survey (Science)
The harm of factless hypotheses (mSphere)
In summary, the era of harm: factless theories (microbeTV)
Stay inside: risk of SARS-CoV-2 transmission in community indoor settings (JID)
Lower levels of household transmission of SARS-CoV-2 VOC Omicron compared to Wild-type: an interplay between transmissibility and immune status (JID)
Long COVID hotline (Columbia : Columbia University Irving Medical Center)
Letters read on TWiV 1170
Dr. Griffin’s COVID treatment summary (pdf)
Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

TWiV 1169: Can anyone hook me up with a duck? Nov 24, 2024

TWiV travels to Brisbane, Australia for the Options XII for the control of influenza conference, and meets up with Stephanie Gras and Jenna Guthmiller to talk about their careers and their research.

Hosts: Vincent Racaniello, Kathy Spindler, and Steph Langel

Guests: Stephanie Gras and Jenna Guthmiller

Subscribe (free): Apple Podcasts, RSS, email

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Links for this episode

Goldilocks zone of influenza immunity (J Inf Dis)
Broadly neutralizing HA antibodies (Nature)
T cell epitopes needed for influenza vaccines (Clin Transl Immunol)
T cell epitopes conserved in emerging H5N1 viruses (Clin Transl Immunol)
Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1168: Clinical update with Dr. Daniel Griffin Nov 23, 2024

In his weekly clinical update, Dr. Griffin briefly discusses the E.coli outbreak associated with onions from McDonald’s before deep diving into the announcement of Robert F Kennedy Jr. nomination for Secretary of Human and Health Services with highlights from MicrobeTV’s own Vincent Racaniello and Paul Offit (Beyond the Noise), the global measles outbreak, underutilization of influenza antivirals for children and teens, the $350 million 2025 order for mpox vaccination, before reviewing the recent statistics on SARS-CoV-2 infection, the WasterwaterScan dashboard, the effectiveness of N95 mask, the interplay between transmission and immunity for virus spread, where to find PEMGARDA, and translational science being conducted to understand long COVID including ongoing clinical trials, development of animal models and how sex may affect outcomes.

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Links for this episode

Micky D’s onions linked to E. colioutbreak….another reason to not eat fast food (CDC)
RFK Jr. series…..does he get anything right? (FactCheck.org)
Salk polio vaccine : a calculated risk? (BMJ)
How to conduct a controlled vaccine trial (American Journal Public Health Nations Health)
Safety and efficacy of BNT162b2 mRNA COVID-19 vaccine (NEJM)
Another Safety and efficacy study: mRNA-1273 SARS-CoV-2 vaccine (NEJM)
…..SERIOUSLY! can’t RFK Jr get it correct? (FactCheck.org)
‘I’ve Come Home Today’: RFK Jr. (the Defenders Children’s Health Defense News & Views)
Thank God for sensible people: Racaniello and Offit (microbeTV)
RFK Jr. : MAN CAN’T YOU GET ANYTHING RIGHT? (Annenberg Public Policy Center: University of Pennsylvania)
No harm in repeating Vinny! Thank God for sensible people: Racaniello and Offit (microbeTV)
Did America think Trump-Kennedy through? …..really did you think this through? (microbeTV)
Make American Healthy Again? ……I will have fries with that….SUPERSIZED! (Wall Street Journal)
Keep the United States HEALTHY! (Safe Communities Coalition)
Measles in the US (CDC Measles: Rubeola)
The merry-go-around of measles (JID)
It is a measles outbreak! (CDC Measles: Rubeola)
10.3 million measles infections in 2023….but no vaccine (WHO)
Underutilization of influenza antiviral treatment among children and adolescents (CDC MMWR)
Increase in influenza infection in children…..(CIDRAP)
Influenza weekly surveillance report: clift notes (CDC FluView)
$340 million doses of mpox vaccine ordered for 2025 (Reuters)
Mpox in NYC (JID)
Respiratory virus activity (CDC Respiratory Illnesses)
COVID-19 deaths (CDC)
COVID-19 national and regional trends (CDC)
Waste water scan for 11 pathogens (WastewaterSCan)
COVID-19 variant tracker (CDC)
SARS-CoV-2 genomes galore (Nextstrain)
N95 Filtering Facepiece Respirator use (JAMA Open Network)
The Risk of SARS-CoV-2 Transmission in Community Indoor Settings (JID)
Lower levels of household transmission of SARS-CoV-2 VOC Omicron compared to Wild-type: an interplay between transmissibility and immune status (JID)
Enhanced placental antibody transfer efficiency with longer interval between maternal RSV vaccination and birth (AJOG: American Journal of Obstetrics and Gynecology)
Where to get pemgarda (Pemgarda)
EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
Fusion center near you….if in NY (Prime Fusions)
CDC Quarantine guidelines (CDC)
NIH COVID-19 treatment guidelines (NIH)
Infectious Disease Society guidelines for treatment and management (ID Society)
Perceptions and Barriers to Outpatient Antiviral Therapy for COVID-19 and Influenza as Observed by Infectious Disease Specialists (OFID)
Drug–Drug Interactions with Nirmatrelvir/Ritonavir(Infectious Diseases and Therapy)
Drug interaction checker (University of Liverpool)
Real-world effectiveness of nirmatrelvir-ritonavir and molnupiravir (CMI: Clinical Microbiology and Infection)
Alleviation of COVID-19 Symptoms and Reduction in Healthcare Utilization Among High-Risk Patients Treated With Nirmatrelvir/Ritonavir (CID)
Molnupiravir safety and efficacy (JMV)
Convalescent plasma recommendation for immunocompromised (ID Society)
What to do when sick with a respiratory virus (CDC)
When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)
Managing healthcare staffing shortages (CDC)
Steroids, dexamethasone at the right time (OFID)
Anticoagulation guidelines (hematology.org)
Daniel Griffin’s evidence based medical practices for long COVID (OFID)
Long-COVID Clinical Trials (RECOVER)
Initiating Long Covid RECOVERy (Science Translational Medicine)
Beyond acute SARS-CoV-2 infection in children (Science Translational Medicine)
Long COVID and Osler’s Web: Chronic Fatigue Syndrome (goodreads)
Sex differences in post infection sequalae (Science Translational Medicine)
Symptoms after Lyme disease: What’s past is prologue (Science Translational Medicine)
Animal models of Long COVID (Science Translational Medicine)
Therapies for Long COVID (Science Translational Medicine)
Sex differences and immune correlates of Long Covid development, symptom persistence, and resolution (Science Translational Medicine)
The Long COVID ISSUE (Science Translational Medicine)
Letters read on TWiV 1168
Dr. Griffin’s COVID treatment summary (pdf)
Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

TWiV 1167: Virus cloak and entry Nov 17, 2024

TWiV reveals a novel H5N1 reassortant virus in Cambodia, circulating vaccine derived poliovirus type 2 in more countries, circulation in the blood of humans of infectious parvovirus B19 coated with active proteases, and B cell receptor dependent enhancement of dengue virus infection.

Hosts: Vincent Racaniello, Dickson Despommier, Kathy Spindler, and Brianne Barker

Subscribe (free): Apple Podcasts, RSS, email

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Links for this episode

MicrobeTV Discord Server
MicrobeTV Fundraiser
Novel H5N1 in Cambodia (medRxiv)
More cVDVP2 circulation (polioeradication.org)
Infectious parvovirus B19 with proteases (Nat Comm)
B cell receptor enhancement of dengue disease (PLoS Path)
Timestamps by Jolene. Thanks!

Weekly Picks

Brianne – See How Many Lives Vaccines Have Saved Around the World based on Lancet study Dickson – 2024 Wildlife Photographer of the Year Kathy – 450 Million year old arthropods preserved in fool’s gold. Primary article Pyrite video Vincent – ‘We need to be ready for a new world’: scientists globally react to Trump election win

Listener Picks

Jack – Coronavirus vaccine update

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1166: Clinical update with Dr. Daniel Griffin Nov 16, 2024

In his weekly clinical update, Dr. Griffin apprises us about the first case of highly pathogenic influenza in Canda, children dying of influenza infection and novel genetic reassortments of the virus, the Marburg virus outbreak in Rwanda, number of mpox infections, before reviewing the recent statistics on SARS-CoV-2 infection, the WasterwaterScan dashboard, how scientific mistrust has affected COVID-19 vaccine administration, resolution of the FDA hold on Novovax’s combination influenza and COVID vaccine, where to find PEMGARDA, how Paxlovid SAVES you money, when to use steroids to treat COVID-19 and how trace amounts of cytokines elicted during SARS-CoV-2 infection negatively impact cardiac function.

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Links for this episode

Bird flu flew into British Columbia Canada (Global News Canada)
H5N1 in British Columbia (CIDRAP)
Highly Pathogenic Avian Influenza flies commercial and domestic (USDA)
Countdown till the end of Marburg outbreak (WHO Rwanda)
First kid’s death due to flu (CIDRAP)
Influenza weekly surveillance report: clift notes (CDC FluView)
H5N1 novel reassortments in migratory birds in China (Emerging Infectious Diseases)
Serologic evidence of recent infection with highly pathogenic avian influenza A (MMWR)
Seriously? 50,000 mpox cases in African outbreak (CIDRAP)
Respiratory virus activity (CDC Respiratory Illnesses)
COVID-19 deaths (CDC)
COVID-19 national and regional trends (CDC)
Waste water scan for 11 pathogens (WastewaterSCan)
COVID-19 variant tracker (CDC)
SARS-CoV-2 genomes galore (Nextstrain)
Science trust: behind COVID 19 vaccine acceptance (Vaccine X)
Vaccine mistrust levels are not budging (Healthday)
FDA clinical hold lifted on Novavax’s combination COVID-flu vaccine(Reuters)
Where to get pemgarda (Pemgarda)
EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
Fusion center near you….if in NY (Prime Fusions)
CDC Quarantine guidelines (CDC)
NIH COVID-19 treatment guidelines (NIH)
Infectious Disease Society guidelines for treatment and management (ID Society)
Drug interaction checker (University of Liverpool)
Real-world effectiveness of nirmatrelvir-ritonavir and molnupiravir (CMI: Clinical Microbiology and Infection)
Alleviation of COVID-19 Symptoms and Reduction in Healthcare Utilization Among High-Risk Patients Treated With Nirmatrelvir/Ritonavir (CID)
Molnupiravir safety and efficacy (JMV)
Convalescent plasma recommendation for immunocompromised (ID Society)
What to do when sick with a respiratory virus (CDC)
When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)
Managing healthcare staffing shortages (CDC)
Steroids, dexamethasone at the right time (OFID)
Anticoagulation guidelines (hematology.org)
Secondary bacterial infection follows COVID-19 (Nature Communications)
Daniel Griffin’s evidence based medical practices for long COVID (OFID)
Post-acute sequelae of SARS-CoV-2 cardiovascular symptoms are associated with trace-level cytokines that affect cardiomyocyte function (Nature Medicine)
Letters read on TWiV 1166
Dr. Griffin’s COVID treatment summary (pdf)
Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

TWiV 1165: What doesn't kill us primes our macrophages Nov 10, 2024

TWiV notes the passing of virologist Diane Griffin, first H5N1 influenza virus in US pigs, Innate immune control of influenza virus interspecies adaptation via IFITM3, and antiviral trained innate immunity in alveolar macrophages after SARS-CoV-2 infection reduces secondary influenza A virus disease.

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, Kathy Spindler, and Brianne Barker

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Links for this episode

MicrobeTV Discord Server
MicrobeTV Fundraiser
Diane Griffin passes (Johns Hopkins)
Diane Griffin on TWiV 453
First H5N1 influenza virus in US pigs (CIDRAP)
IFITM3 controls interspecies influenza virus infection (Nat Comm)
Trained innate immunity by alveolar macrophages (Immunity)
Timestamps by Jolene. Thanks!

Weekly Picks

Angela – See a giant ‘ghost particle’ detector and more — October’s best science images Brianne – October 27 APoD: Bat nebula Dickson – Nikon Small World Contest 2024 winners Kathy – AAAS 150th anniversary video, celebrating scientists and Pew’s 2024 annual Trust in Science survey findings Rich – Cats Basically Are a Liquid After All, Study Confirms Alan – HHMI’s Beautiful Biology site Vincent – EcoHealth Alliance Fights Back

Listener Picks

Hunter – Don’t stop me now: Queen’s Brian May on saving badgers — and the scientific method Anne – Reasons to be cheerful

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1164: Clinical update with Dr. Daniel Griffin Nov 09, 2024

In his weekly clinical update, Dr. Griffin informs us about the World Health Organization research and development plan to combat endemic pathogens including hepatitis C virus, RSV and dengue virus, another case of mpox in Britian, the Marburg virus outbreak in Rwanda, before reviewing the recent statistics on SARS-CoV-2 infection, the WasterwaterScan dashboard, if there is a benefit to additional COVID vaccinations after the initial series, ISDA guideline for using anti-SARS-CoV-2 monoclonal antibody therapy for prophylaxis, where to find PEMGARDA, a reminder of how and when to use steroids to treat COVID-19, if and how do severe secondary bacterial infections develop following SARS-CoV-2 infection, and if COVID-19 associates with a risk of autoimmune and autoinflammatory connective tissue disorders.

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Links for this episode

Is the WHO the world’s NIH: endemic pathogens initiative (eBioMedicine)
Another two cases of mpox in Britian (Reuters)
How to stop Marburg virus (Rwanda Biomedical Centre)
Marburg Virus fact sheet (Rwanda Biomedical Centre)
Influenza weekly surveillance report: cliff notes (CDC FluView)
RSV NETwork (CDC RSV)
Respiratory virus activity (CDC Respiratory Illnesses)
COVID-19 deaths (CDC)
COVID-19 national and regional trends (CDC)
Waste water scan for 11 pathogens (WastewaterSCan)
COVID-19 variant tracker (CDC)
SARS-CoV-2 genomes galore (Nextstrain)
Symptom reduction after additional vaccine dose during Omicron (OFID)
IDSA Guideline update for SARS-CoV-2 monoclonal antibody pemivibart pre-exposure prophylaxis (CID)
Where to get pemgarda (Pemgarda)
EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
Fusion center near you….if in NY (Prime Fusions)
CDC Quarantine guidelines (CDC)
NIH COVID-19 treatment guidelines (NIH)
Infectious Disease Society guidelines for treatment and management (ID Society)
Drug interaction checker (University of Liverpool)
Molnupiravir safety and efficacy (JMV)
Convalescent plasma recommendation for immunocompromised (ID Society)
What to do when sick with a respiratory virus (CDC)
When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)
Managing healthcare staffing shortages (CDC)
Steroids, dexamethasone at the right time (OFID)
Anticoagulation guidelines (hematology.org)
Secondary bacterial infection follows COVID-19 (Nature Communications)
Daniel Griffin’s evidence-based medical practices for long COVID (OFID)
Autoimmune and autoinflammatory connective tissue disorders following COVID-19 (JAMA Dermatology)
Letters read on TWiV 1164
Dr. Griffin’s COVID treatment summary (pdf)
Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

TWiV 1163: Hepadnaviridae in the heartland Nov 03, 2024

From the 2024 International Hepatitis B virus meeting in Chicago, TWiV speaks with Mala Maini and John Tavis about their careers, the replication and transmission of HBV, and the HBV Foundation.

Hosts: Vincent Racaniello and Rich Condit

Guests: Mala Maini and John Tavis

Subscribe (free): Apple Podcasts, RSS, email

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Links for this episode

MicrobeTV Discord Server
Immunobiology and pathogenesis of hepatitis B virus infection (Nat Rev Immunol)
HBV Foundationhttps://www.hepb.org/
Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1162: Clinical update with Dr. Daniel Griffin Nov 02, 2024

In his weekly clinical update, Dr. Griffin informs us about “walking pneumonia”, the phase of the polio supplemental immunization campaign in Gaza, mpox circulation, the Marburg virus outbreak in Rwanda, the beginning of influenza season, before reviewing the recent statistics on SARS-CoV-2 infection, the WasterwaterScan dashboard, contrasting public health concerns between the US and the UK, if mRNA boosters affect mucosal immunity against SARS-CoV-2 infection, where to find PEMGARDA, a reminder of how and when to use steroids to treat COVID-19, if antiviral therapy prevents long COVID and viral sequalae in healthy young marines.

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Links for this episode

Mycoplasma pneumoniae infections increasing (CDC)
Polio vaccination campaign restarts (Reuters)
North Gaza polio campaign postponed (Reuters)
1St clade 1b mpox in UK (GOV.UK)
UK imports mpox (CIDRAP)
Clinical trial of MVA-BN for children (Bavarian-Nordic)
How to stop Marburg virus (Rwanda Biomedical Centre)
Marburg Virus fact sheet (Rwanda Biomedical Centre)
Laboratory confirmed influenza associated hospitalizations 2010-2023 (CDC)
Influenza weekly surveillance report: cliff notes (CDC FluView)
Mucosal nirsevimab levels in breakthrough bronchiolitis (LANCET Infectious Diseases)
RSV NETwork (CDC RSV)
Respiratory virus activity (CDC Respiratory Illnesses)
COVID-19 deaths (CDC)
COVID-19 national and regional trends (CDC)
Waste water scan for 11 pathogens (WastewaterSCan)
UK public health data tracker (UKHSA)
COVID-19 variant tracker (CDC)
SARS-CoV-2 genomes galore (Nextstrain)
Repeat COVID-19 mRNA vaccination contributes to mucosa immunity (Science Translational Medicine)
XBB.1.5 mRNA booster vaccination limited mucosal immunity (Science Translational Medicine)
I repeat: COVID mRNA booster vaccinations suboptimal respiratory mucosal immunity (Science Translational Medicie)
Facial Palsy after COVID-19 vaccination? (Emerging Infectious Diseases)
New preventive COVID-19 agent (ISDA)
IDSA Guidelines on the Treatment and Management of Patients with COVID-19 (IDSA)
Where to get pemgarda (Pemgarda)
EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
Fusion center near you….if in NY (Prime Fusions)
CDC Quarantine guidelines (CDC)
NIH COVID-19 treatment guidelines (NIH)
Infectious Disease Society guidelines for treatment and management (ID Society)
Viral and symptom rebound following monoclonal antibody therapy (JID)
Drug interaction checker (University of Liverpool)
Nirmatrelvir plus ritonavir reduces COVID-19 hospitalization and prevents long COVID (Scientific Reports)
Molnupiravir safety and efficacy (JMV)
Convalescent plasma recommendation for immunocompromised (ID Society)
Time to Sustained Recovery Among Outpatients With COVID-19 Receiving Montelukast vs Placebo (JAMA Network Open)
What to do when sick with a respiratory virus (CDC)
When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)
Managing healthcare staffing shortages (CDC)
Steroids, dexamethasone at the right time (OFID)
Anticoagulation guidelines (hematology.org)
Clinical and functional assessment of SARS-CoV-2 sequelae among young marines
(LANCET: Regional Health Americas)
Letters read on TWiV 1162
Dr. Griffin’s COVID treatment summary (pdf)
Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

TWiV 1161: Baby you can drive my gene Oct 27, 2024

TWiV reviews continuing expansion of poliovirus type 2, removal of influenza B/Yamagata from the vaccine, Nobel Prize for miRNAs, protective immune response with a adenovirus-associated virus vector expressing a computationally designed hemagglutinin, and viral gene drive during herpes simplex 1 infection in mice.

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, Kathy Spindler, and Brianne Barker

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Links for this episode

MicrobeTV Discord Server
Continued expansion of type 2 poliovirus (reliefweb)
No more polio case map at polioeradication.org
B/Yamagata removed from flu vaccine (NPR)
Nobel Prizes for miRNA (ScienceInsider)
AAV-vectored influenza vaccine (J Virol)
Herpesvirus type 1 gene drive in mice (Nat Commun)
Timestamps by Jolene. Thanks!

Weekly Picks

Brianne – Virus and Vaccines Information Page from NIH All of Us Research Program Kathy – For a Pivotal Vaccine: Trial, Error and Two Young Lives Rich – October 17 2024 APOD: The Clipper and the Comet Alan – Opening a deep-sea vent with a crowbar Vincent – The expanding world of neuroscience

Listener Pick

Jason – Solar eclipse on Mars and Polaris Program and their Harmony of Resilience Ryan – New York’s childhood vaccine coverage remains high

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1160: Clinical update with Dr. Daniel Griffin Oct 26, 2024

In his weekly clinical update, Dr. Griffin informs us about mpox circulation, the Marburg virus outbreak in Rwanda, new recommendations for the RSV and pneumococcal vaccines by the CDC, the beginning of influenza season, before reviewing the recent statistics on SARS-CoV-2 infection, the WasterwaterScan dashboard, contrasting public health concerns between the US and the UK, what the risk of SARS-CoV-2 transmission is when indoors, the difference between NVX-CoV2327 and BNT162b2 for adolescents, why 65 years and older should get a second boost of the COVID-19 vaccine, where to find PEMGARDA, a reminder of how and when to use steroids to treat COVID-19, the clinical trial for evaluating how novel treatments of COVID-19 affect long COVID and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome after SARS-CoV-2 infection.

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Links for this episode

Grim marker: mpox over a 1000 deaths in Africa (CIDRAP)
Global trend of mpox outbreak 2022-2024 (WHO)
Second time mpox is a global public health emergency (Reuters)
Mpox variant in Germany (Reuters)
Epidemiological analysis of confirmed mpox cases in Burundi (EuroSurveillance)
The 63rd case of Marburg virus infections in Rwanda (CIDRAP)
How to stop Marburg virus (Rwanda Biomedical Centre)
Marburg virus fact sheet (Rwanda Biomedical Centre)
FDA approves RSV vaccine ABRYSVO for 18-59 individuals of increased risk (Pfizer)
Respiratory syncytial virus infection-NET (CDC)
New pneumococcal vaccine recommendations…..it’s a virus? (CDC Newsroom)
Recommending PREVNAR 20, 20 valent pneumococcal conjugate vaccine for 50 and over (Pfizer)
And one more, CAPVEXIVE, pneumococcal 21 valent conjugate vaccine (Merck)
Penumococcoal 21-valent conjugate vaccine CAPVEXIVE(MerckVaccines.com)
Influenza surveillance: Key updates (CDC)
COVID-19 deaths (CDC)
COVID-19 national and regional trends (CDC)
Waste water scan for 11 pathogens (WastewaterSCan)
What is happening across the pond? (UKHSA data dashboard)
COVID-19 variant tracker (CDC)
SARS-CoV-2 genomes galore (Nextstrain)
Risk of SARS-CoV-2 transmission when indoors (JID)
NVX-CoV2327 vs BNT162b2 vaccines in adolescents (Pediatric Infectious Disease Journal)
Second dose of 2024-2025 COVID19 vaccine recommended for 65 and older (CDC Newsroom)
New preventive COVID-19 agent (ISDA)
IDSA Guidelines on the Treatment and Management of Patients with COVID-19 (IDSA)
Where to get pemgarda (Pemgarda)
EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
CDC Quarantine guidelines (CDC)
NIH COVID-19 treatment guidelines (NIH)
Infectious Disease Society guidelines for treatment and management (ID Society)
Viral and symptom rebound following monoclonal antibody therapy (JID)
Drug interaction checker (University of Liverpool)
Molnupiravir safety and efficacy (JMV)
Convalescent plasma recommendation for immunocompromised (ID Society)
What to do when sick with a respiratory virus (CDC)
When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)
Managing healthcare staffing shortages (CDC)
Steroids,dexamethasone at the right time (OFID)
Anticoagulation guidelines (hematology.org)
ASH living guidelines on use of anticoagulation for thromboprophylaxis in patients with COVID-19: executive summary, Dr. Daniel Griffin (Blood Advances)
Novel treatments for acute COVID-19 should account for long COVID (JID) The persistence of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) after SARS-CoV-2 infection (Journal of Infection)
Letters read on TWiV 1160
Dr. Griffin’s COVID treatment summary (pdf)
Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

TWiV 1159: Eliminating cervical cancer, and endometrial immunity Oct 20, 2024

Vincent travels to the Karolinska Institute in Stockholm to meet up with Niklas Björkström and Joakim Dillner to review their research on the endometrial immune system, and the plan to eliminate cervical cancer in Sweden.

Host: Vincent Racaniello

Guests: Niklas Björkström and Joakim Dillner

Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email

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Links for this episode

MicrobeTV Discord Server
Endometrial immune system variation (Sci Immunol)
Immune defense in the womb (News from Karolinska)
HPV vaccination and screening for elimination (Nat Comm)
Cervical cancer elimination strategies (Int J Cancer)
Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1158: Clinical update with Dr. Daniel Griffin Oct 19, 2024

In his weekly clinical update, Dr. Griffin informs us about mpox circulation and new vaccine approval, the Marburg virus outbreak in Rwanda, and the largest outbreak of whooping cough in a decade before reviewing the recent statistics on SARS-CoV-2 infection, the WasterwaterScan dashboard, immunity among those over 65th following the 3rd dose of the COVID-19 mRNA vaccine, where to find PEMGARDA, a reminder of how and when to use steroids to treat COVID-19, how well the SARS-CoV-2 rapid antigen test performed, what do when healthcare workers succumb to SARS-CoV-2 infection, the effect of remdesivir on survival and readmission of hospitalized patients, if cognitive impairment following virus infection impairs one’s driving and how long COVID affects Chinese society.

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Links for this episode

Undiagnosed MPXV infections are high in men who have sex with men (BMC Infectious Diseases)
WHO, now a vaccine approval agency, Jynneos for teens (CIDRAP)
Mpox outbreak global trends (WHO)
How to stop Marburg virus (Rwanda Biomedical Centre)
Marburg virus fact sheet (Rwanda Biomedical Centre)
Largest whooping cough outbreak in US in a decade (NPR)
COVID-19 deaths (CDC)
COVID-19 national and regional trends (CDC)
Waste water scan for 11 pathogens (WastewaterSCan)
COVID-19 variant tracker (CDC)
SARS-CoV-2 genomes galore (Nextstrain)
Insurance relates to effectiveness and waning of immunity following 3rd dose of mRNA COVID-19 vaccine? (JID)
New preventive COVID-19 agent (ISDA)
IDSA Guidelines on the Treatment and Management of Patients with COVID-19 (IDSA)
Where to get pemgarda (Pemgarda)
EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
How well do you test: performance of the SARS-CoV-2 antigen rapid detection test (eBioMedicine)
CDC Quarantine guidelines (CDC)
NIH COVID-19 treatment guidelines (NIH)
Infectious Disease Society guidelines for treatment and management (ID Society)
Drug interaction checker (University of Liverpool)
Molnupiravir safety and efficacy (JMV)
Convalescent plasma recommendation for immunocompromised (ID Society)
What to do when sick with a respiratory virus (CDC)
When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)
Managing healthcare staffing shortages (CDC)
Steroids, dexamethasone at the right time (OFID)
Anticoagulation guidelines (hematology.org)
Remdesivir-associated survival outcomes among immunocompromised patients (CID)
Remdesivir Effectiveness in Reducing the Risk of 30-day Readmission in Vulnerable Patients (CID)
Measurement of circulating viral antigens post-SARS-CoV-2 infection (CMI: Clinical Microbiology and Infection)
DUCI: driving under cognitive influence of COVID-19 (Neurology)
Long COVID facts and findings: (LANCET: Regional Health Western Pacific)
Letters read on TWiV 1158
Dr. Griffin’s COVID treatment summary (pdf)
Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

TWiV 1157: Superworm liquefaction and a pandemic prophylactic Oct 13, 2024

TWiV reviews Marburg virus outbreak in Rwanda, cryo-EM based discovery of a parvovirus causing black wasting disease in farmed beetles, and a mosaic nanoparticle experimental vaccine that elicits cross-reactive sarbecovirus responses in pre-vaccinated animals.

Hosts: Vincent Racaniello, Alan Dove, and Brianne Barker

Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email

Become a patron of TWiV!

Links for this episode

MicrobeTV Discord Server
Marburg virus disease, Rwanda (WHO)
Suspected German Marburg case tests negative (Politico)
Cryo-EM discovery of insect parvovirus (Cell)
Mosaic sarbecovirus nanoparticle experimental vaccine (Cell)
Letters r ead on TWiV 1157
Timestamps by Jolene. Thanks!

Weekly Picks

Brianne – ASM Lesson Plans Alan – A City on Mars, and this blog by a ham radio operator hit by Hurricane Helene Vincent – How to Win A Nobel Prize

Listener Pick

Laura – Science of Public Communication (original article)

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1156: Clinical update with Dr. Daniel Griffin Oct 12, 2024

In his weekly clinical update, Dr. Griffin updates us about polio SIA campaign in Gaza, the durability of protection following administration of GSK’s recombinant antigen RSV vaccine, mpox in an Ugandan jail, the Marburg virus outbreak in Rwanda, before reviewing the recent statistics on SARS-CoV-2 infection, the WasterwaterScan dashboard, immunogenicity, reactogenicity and safety of different COVID-19 vaccine platforms, disease severity in those not previously vaccinated with those vaccinated but not infected, where to find PEMGARDA, a reminder of how and when to use steroids to treat COVID-19, what do when healthcare workers succumb to SARS-CoV-2 infection, if COVID-19 doubles the risk for heart attacks, stroke and death and if COVID-19 affects the regions of the brainstem.

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Links for this episode

Polio: second round of vaccination in Gaza (Reuters)
Season 3 for GSK RSV vaccine protection (CIDRAP)
Positive data for Arexvy, the respiratory syncytial virus vaccine (GSK)
Mpox convicted felon: in Ugandan prison (Reuters)
How to stop Marburg virus (Rwanda Biomedical Centre)
Marburg virus fact sheet (Rwanda Biomedical Centre)
CDC summary of the “Rwanda Marburg Situation” (CDC)
700 doses of a Marburg vaccine from the Sabin Vaccine Institute to Rwanda (CIDRAP)
USAID mobilizes Marburg outbreak response in Rwanda (United States Agency International Development)
COVID-19 deaths (CDC)
COVID-19 national and regional trends (CDC)
Waste water scan for 11 pathogens (WastewaterSCan)
COVID-19 variant tracker (CDC)
SARS-CoV-2 genomes galore (Nextstrain)
PICOBOO: immunogenicity, reactogenicity and safety of different COVID-19 vaccine (Journal of Infection)
COVID-19 in previously unvaccinated compared with previously uninfected vaccinated (JID)
New preventive COVID-19 agent (ISDA)
IDSA Guidelines on the Treatment and Management of Patients with COVID-19 (IDSA)
Where to get pemgarda (Pemgarda)
EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
CDC Quarantine guidelines (CDC)
NIH COVID-19 treatment guidelines (NIH)
Infectious Disease Society guidelines for treatment and management (ID Society)
COVID Data tracker (CDC
Differences in COVID-19 outpatient antiviral treatment (MMWR)
Drug interaction checker (University of Liverpool)
Molnupiravir safety and efficacy (JMV)
Convalescent plasma recommendation for immunocompromised (ID Society)
What to do when sick with a respiratory virus (CDC)
When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)
Managing healthcare staffing shortages (CDC)
Steroids,dexamethasone at the right time (OFID)
Anticoagulation guidelines (hematology.org)
COVID-19 is a coronary artery disease with genetic interaction with ABO blood type (AHAIASA Journals)
COVID-19 doubles risk of heart attack, stroke and death (EurekaAlert!)
QTL mapping at 7T in COVID-19: brainstem and outcomes (Brain)
Letters read on TWiV 1156
Dr. Griffin’s COVID treatment summary (pdf)
Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

TWiV 1155: Spillover in stall A Oct 06, 2024

TWiV reviews mask effectiveness against respiratory infections, EEE death in NY State, viruses with zoonotic potential in farmed fur animals, and genetic tracing of market wild life and viruses at the Huanan Seafood Market, the epicenter of the COVID-19 pandemic.

Hosts: Vincent Racaniello, Alan Dove, and Rich Condit

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Links for this episode

MicrobeTV Discord Server
Review confirms mask effectiveness (original article)
EEE death in Ulster County NY (CBS News)
EEE on TWiV 1145
Viruses of farmed fur animals (Nature)
Tracing of wildlife and viruses at COVID-19 epicenter (Cell)
Letters read on TWiV 1155
Timestamps by Jolene. Thanks!

Weekly Picks

Rich – Immunize.org, Vaccineinformation.org, National Network of Immunization Coalitions Alan – Birdcast Vincent – A universal framework for inclusive 15-minute cities

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1154: Clinical update with Dr. Daniel Griffin Oct 05, 2024

In his weekly clinical update, Dr. Griffin discusses the Marburg virus outbreak in Rwanda, the lack of immune durability following pertussis vaccination, recommendations for maternal vaccination and antibody therapy to protect against infant RSV, vaccine security for Mpox, before reviewing the recent statistics on SARS-CoV-2 infection, the WasterwaterScan dashboard, how to put on and take off PPE to avoid contamination, where to find PEMGARDA, a reminder of how and when to use steroids to treat COVID-19, what do when healthcare workers succumb to SARS-CoV-2 infection, the lack of immune durability elicited by mRNA vaccine and the finding of how SARS-CoV-2 infection impacts memory, cognition and reduces grey matter volume.

Subscribe (free): Apple Podcasts, RSS, email

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Links for this episode

Rwanda: Marburg virus disease (WHO)
Passport required?…..Marburg virus commutes to Germany (CIDRAP)
Outbreak of whooping cough/pertussis…..no lifelong immunity following vaccination? (Bloomberg
Protection of infants by maternal antibodies against RSV by either vaccination or nirsevimab (MMWR)
WHO recommendations for RSV: maternal vaccination and antibody shot (Reuters)
Ziresovir for RSV hospitalized infants (NEJM)
Crawling to effective anti-RSV countermeasures (NEJM)
The $800 million pledge for African mpox response (Reuters)
COVID-19 deaths (CDC)
COVID-19 national and regional trends (CDC)
Waste water scan for 11 pathogens (WastewaterSCan)
COVID-19 variant tracker (CDC)
SARS-CoV-2 genomes galore (Nextstrain)
Doffing your PPE– contact precautions (CID)
mRNA vaccination does not elicit durable immune response (Nature Medicine)
IDSA Guidelines on the Treatment and Management of Patients with COVID-19 (IDSA)
Where to get pemgarda (Pemgarda)
EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
CDC Quarantine guidelines (CDC)
NIH COVID-19 treatment guidelines (NIH)
Infectious Disease Society guidelines for treatment and management (ID Society)
Drug interaction checker (University of Liverpool)
Molnupiravir safety and efficacy (JMV)
Convalescent plasma recommendation for immunocompromised (ID Society)
What to do when sick with a respiratory virus (CDC)
When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)
Managing healthcare staffing shortages (CDC)
Steroids,dexamethasone at the right time (OFID)
Anticoagulation guidelines (hematology.org)
Mechanisms of long COVID and therapeutics (Cell)
Post hospitalization cognitive deficits and grey matter reduction 1 year after COVID-19 (Nature Medicine)
Letters read on TWiV 1154
Dr. Griffin’s COVID treatment summary (pdf)
Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

TWiV 1153: Viruses that (can) make you well Sep 29, 2024

From the Viruses of Microbes meeting in Cairns, Australia, TWiV speaks with Krystyna and Rob about their research on using bacteriophages to treat bacterial infections.

Hosts: Vincent Racaniello and Jolene Ramsey

Guests: Krystyna Dabrowska and Rob Lavigne

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Links for this episode

MicrobeTV Discord Server
Viruses of Microbes 2024
Immune responses to phages (Front Immunol)
Engineering bacteriolytic enzymes (Front Immunol)
100 cases of phage therapy (Nat Micro)
Synthetic biology potential of bacteriophages (Nat Micro)
Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1152: Clinical update with Dr. Daniel Griffin Sep 28, 2024

In his weekly clinical update, Dr. Griffin deep dives into the durability of the antibody response following mpox vaccination, vaccine security, global mpox circulation, the origins of SARS-CoV-2, including a list TWiV episodes and combatting scientific misinformation, before reviewing the recent statistics on SARS-CoV-2 infection, the WasterwaterScan dashboard, where to find PEMGARDA, a reminder of how and when to use steroids to treat COVID-19, what do when healthcare workers succumb to SARS-CoV-2 infection, if remdesivir + dexamethasone lowers mortality of hospitalized COVID-19 patients and the finding of how SARS-CoV-2 infection impacts memory and cognition.

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Links for this episode

Waning vaccine protection against mpox…..isn’t this the way the humoral immune response works? (CIDRAP) 1:46
Uncontrollable mpox outbreak in Africa (Reuters) 4:10
Antibodies elicited by the Jynneos vaccine against mpox contract after 6-9 months….can you believe? (medrxiv) 4:45
Mpox vaccine for adolescents approved (Pharmaceutical Technology) 14:05
Clade 1b mpox visiting India (CIDRAP) 15:05
Mpox clade 1b in Kerala (ANI South Asia’s Leading Multimedia News Agency) 15:13
US government orders $63M worth of small pox/mpox vaccine (Reuters) 15:34
Mpox donations boosting global supply (US Department of Health and Human Services)
1 million mpox vaccine doses for Africa….with love from US government (CIDRAP) 15:55
Speed doses of mpox vaccine (CIDRAP)
Mpox vaccine donations (UNICEF) 17:35
Bavarian Nordic mpox vaccine (Yahoo finances)
Early epicenter of COVID-19 pandemic Huanan seafood market (Science) 23:07
Wildlife trade likely source of SARS-CoV-2 (Science) 23:16
Zoonotic origins of SARS-CoV-2 (Science) 23:20
Surveillance at the Huanan Seafood market (Europe PMC) 25:03
TWiV shout outs…..all for the SARS-CoV-2 spill over from nature 25:31
- TWiV 1019: Eddie Holmes on SARS-CoV-2 origins
- TWiV 1017: From Nature, not a lab
- TWiV 995: Viral origin stories
- TWiV 940: Eddie Holmes in on viral origins
- TWiV 876: Spillover market with Michael Worobey
- TWiV 762: SARS-CoV-2 origins with Robert Garry
- TWiV 760: SARS-CoV-2 origins with Peter Daszak, Thea Kølsen Fischer, Marion Koopmans
- TWiV 774: Kristian Andersen, Robert Garry, and the deleted SARS-CoV-2 sequences
Genetic tracing of market wildlife and viruses at Huanan Market (Cell) 18:56
Combatting scientific misinformation (microbeTV: TWiV) 34:14
COVID-19 deaths (CDC) 35:20
COVID-19 national and regional trends (CDC)
Waste water scan for 11 pathogens (WastewaterSCan)
COVID-19 variant tracker (CDC)
SARS-CoV-2 genomes galore (Nextstrain)
Suggestion for the use of a new preventive COVID-19 agent (IDSA)
IDSA Guidelines on the Treatment and Management of Patients with COVID-19 (IDSA)
Where to get pemgarda (Pemgarda)
EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
CDC Quarantine guidelines (CDC)
NIH COVID-19 treatment guidelines (NIH)
Infectious Disease Society guidelines for treatment and management (ID Society)
Drug interaction checker (University of Liverpool)
Molnupiravir outcomes 3 and 6 months after treatment (LANCET Infectious Diseases)
Antivirals and post-COVID-19 conditions (LANCET Infectious Disease)
Molnupiravir safety and efficacy (JMV)
Convalescent plasma recommendation for immunocompromised (ID Society)
What to do when sick with a respiratory virus (CDC)
When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)
Managing healthcare staffing shortages (CDC)
Steroids, dexamethasone at the right time (OFID)
Anticoagulation guidelines (hematology.org)
Lower mortality risk associated with remdesivir + dexamethasone versus dexamethasone for hospitalized COVID-19 patients (CID) 39:17
Changes in memory and cognition during the SARS-CoV-2 human challenge study (eClinical Medicine) 42:25
Letters read on TWiV 1152 48:18
Dr. Griffin's COVID treatment summary (pdf)
Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

TWiV 1151: Hotel California for Phage Sep 22, 2024

TWiV reviews polio vaccination campaign in Gaza, viruses with zoonotic potential in farmed fur animals, low HPV vaccination in North Texas associated with high rates of cervical cancer, a large flavivirus genome that does not encode error correction machinery, and antiphage defense through inhibition of virion assembly.

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Jolene Ramsey

Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email

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Links for this episode

MicrobeTV Discord Server
Polio vaccination in Gaza (Reuters)
Zoonotic viruses in farmed fur animals (Nature)
HPV vaccination and cancer rates (JAMA Net Open)
40 kb RNA genome without error correction (PNAS)
Stopping the phage tape measure protein (Nat Commun)
Tail assembly interference (Nat Commun)
Letters read on TWiV 1151
Timestamps by Jolene. Thanks!

Weekly Picks

Dickson – Digital nature pics winners 2024 Wildlife Photographer of the Year Alan – Adorable story about a Nigerian paralympian couple who are both polio survivors Jolene – Capsid assembly model with self-assembling pentamers in 3D print model (plus three more models now available if search self assembling virus) and Wonderlab article about exhibit using this to teach about viral patterns in Bloomington Indiana Science museum Vincent – The collapse of bat populations led to more than a thousand infant deaths

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1150: Clinical update with Dr. Daniel Griffin Sep 21, 2024

In his weekly clinical update, Dr. Griffin dives into West Nile virus in New Jersey, poliovirus vaccination campaign in Gaza and Afghanistan, California dengue virus infections, children dying from flu, mpox vaccination procurement and antiviral usage, flu circulation in US, before reviewing the recent statistics on SARS-CoV-2 infection, finding a new wasterwater dashboard, if the monovalent XBB.1.5 COVID-19 vaccine is effective against circulating SARS-CoV-2 isolates, the need for nasal mucosal IgA in response to SARS-CoV-2 infection, where to find PEMGARDA, does administration of molnupiravir reduce symptoms in the vaccinated, when to use convalescent plasma, how molnupiravir treatment leads to better outcomes 3 and 6 months after treatment, a reminder of how and when to use steroids to treat COVID-19, what do when healthcare workers succumb to SARS-CoV-2 infection, if vaccination against SARS-CoV-2 does protect against long COVID, and if those taking the anti-diabetic drug metformin have higher or lower incidences of long COVID.

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Links for this episode

West Nile virus in New Jersey (CBSNews)
Poliovirus vaccination 90% coverate (Reuters)
Suspension of poliovirus eradication by the Taliban (apnews)
California dengue cluster (CIDRAP)
Children dying of influenza (CIDRAP)
199 children deaths from flu (CDC)
Bavarian Nordic mpox vaccine (Yahoo finances)
Prequalification of MVA-BN mpox vaccine (WHO Int)
Speed doses of mpox vaccine (CIDRAP)
GAVI rapidly secures 500K doses of mpox vaccines for Africa(GAVI)
Expanded access to teconvirimat for mpox treatment in US 2022-2023(NEJM Evidence)
FluView (CDC)
Human to human transmission of bird flu in Missouri? (NY Times)
Bird flu isolated from humans in Missouri similar to that found in cattle (CNN)
COVID-19 deaths (CDC)
COVID-19 national and regional trends (CDC)
Waste water scan for 11 pathogens (WastewaterSCan)
COVID-19 variant tracker (CDC)
SARS-CoV-2 genomes galore (Nextstrain)
Effectiveness of Updated 2023–2024 (Monovalent XBB.1.5) COVID-19 Vaccination Against SARS-CoV-2 Omicron XBB and BA.2.86/JN.1 Lineage (CID)
Early, robust mucosal secretory IgA but not IgG response to SARS-CoV-2 spike in oral fluid is associated with faster viral clearance and COVID-19 symptom resolution (JID)
Suggestion for the use of a new preventive COVID-19 agent (IDSA)
IDSA Guidelines on the Treatment and Management of Patients with COVID-19 (IDSA)
Where to get pemgarda (Pemgarda)
EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
CDC Quarantine guidelines (CDC)
NIH COVID-19 treatment guidelines (NIH)
Infectious Disease Society guidelines for treatment and management (ID Society)
Drug interaction checker (University of Lierpool)
Molnupiravir outcomes 3 and 6 months after treatment (LANCET Infectious Diseases)
Antivirals and post-COVID-19 conditions (LANCET Infectious Disease)
Molnupiravir safety and efficacy (JMV)
Convalescent plasma recommendation for immunocompromised (ID Society)
What to do when sick with a respiratory virus (CDC)
When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)
Managing healthcare staffing shortages (CDC)
Steroids, dexamethasone at the right time (OFID)
Anticoagulation guidelines (hematology.org)
Metformin use in adults with diabetes and incidence of long COVID (Diabetes Care)
Letters read on TWiV 1150
Dr. Griffin’s COVID treatment summary (pdf)
Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

TWiV 1149: Mary Estes, a gutsy virologist Sep 15, 2024

From the annual meeting of the American Society for Virology, Kathy and Brianne speak with Mary Estes about her career and the research of her laboratory on viruses that infect the gastrointestinal tract, including rotavirus and norovirus.

Hosts: Kathy Spindler and Brianne Barker

Guest: Mary Estes

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Links for this episode

MicrobeTV Discord Server
Diarrhea induced by rotavirus NSP4 (Science)
Minimal infective dose of rotavirus (Arch Virol)
mRNA release from rotavirus particles (Nat Struct Biol)
Norovirus vaccine (Clin Ther)
Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1148: Clinical update with Dr. Daniel Griffin Sep 14, 2024

In his weekly clinical update, Dr. Griffin dives into “pandemic potential” viruses isolated from farmed fur animals, how the mRNA and pox vectored vaccines against mpox spar against each other, how telehealth does managing mpox, and if prophylactic use of the anti-RSV monoclonal for infants is cost-effective before reviewing the recent statistics on SARS-CoV-2 infection, if viral load correlates to one vaccination status, where to find PEMGARDA, does administration of molnupiravir reduce symptoms in the vaccinated, when to use convalescent plasma, how molnupiravirs treatment leads to better outcomes 3 and 6 months after treatment, a reminder of how and when to use steroids to treat COVID-19, what do when healthcare workers succumb to SARS-CoV-2 infection, if vaccination against SARS-CoV-2 does protect against long COVID, and if SARS-CoV-2 during Omicron alters ones’ micriobiota.

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Links for this episode

Lending you the viruses in my fur (Nature)
mRNA or vaccinia based mpox vaccine (Cell)
Virtual outpatient management of mpox (OFID)
NYC: mpox vaccination finder (NYC)
Vaccine, mpox/COVID-19 near you (NYC)
Expensive or not expensive anti-RSV monoclonal therapy for infants (American Academy of Pediatrics)
COVID-19 deaths (CDC)
COVID-19 national and regional trends (CDC)
COVID-19 variant tracker (CDC)
SARS-CoV-2 genomes galore (Nextstrain)
Association of vaccination and SARS-CoV-2 viral load phase 3 (JID)
IDSA Guidelines on the Treatment and Management of Patients with COVID-19 (IDSA)
Where to get pemgarda (Pemgarda)
EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
Early phase of SARs-CoV-2 infection (COVID.gov)
CDC Quarantine guidelines (CDC)
NIH COVID-19 treatment guidelines (NIH)
Infectious Disease Society guidelines for treatment and management (ID Society)
Drug interaction checker (University of Liverpool)
Molnupiravir outcomes 3 and 6 months after treatment (LANCET Infectious Diseases)
Antivirals and post-COVID-19 conditions (LANCET Infectious Disease)
Molnupiravir safety and efficacy (JMV)
Convalescent plasma recommendation for immunocompromised (ID Society)
What to do when sick with a respiratory virus (CDC)
When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)
Managing healthcare staffing shortages (CDC)
Steroids, dexamethasone at the right time (OFID)
Anticoagulation guidelines (hematology.org)
Long COVID following infection with Omicron: oral microbiota changes(American Journal of Medicine)
Letters read on TWiV 1148
Dr. Griffin’s COVID treatment summary (pdf)
Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

TWiV 1147: Breastmilk paradox for norovirus Sep 08, 2024

TWiV reviews multi-country outbreak of Mpox, first face covering ban in Nassau County NY, case of polio in India, more in US accept vaccine misinformation, other wartime diseases in Gaza besides polio, a new scientist run virus genome database, Mpox epidemiology and vaccine effectiveness in England, and metabolic immaturity and breastmilk bile acid metabolites determine heightened newborn vulnerability to norovirus diarrhea.

Hosts: Vincent Racaniello, Rich Condit, and Brianne Barker

Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email

Become a patron of TWiV!

Links for this episode

MicrobeTV Discord Server
Multi-country Mpox outbreak (WHO)
Face covering ban in Nassau County (NBC)
Polio case in India (Business Standard)
More acceptance of vaccine misinformation (EurekAlert)
War in Gaza not just causing polio (Jerusalem Post)
Scientist run virus genome database (Science)
Mpox epidemiology and vaccine effectiveness (Emerg Inf Dis)
Newborn vulnerability to norovirus diarrhea (Cell Host Microbe)
Timestamps by Jolene. Thanks!

Weekly Picks

Brianne – Viral adaptation to climate change Rich – “Understanding the biology of monkeypox virus to prevent future outbreaks” by B. Moss Vincent – We can now watch Grace Hopper’s famed 1982 lecture on YouTube

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1146: Clinical update with Dr. Daniel Griffin Sep 07, 2024

In his weekly clinical update, Dr. Griffin discusses seasonal influenza vaccine recommendations from the CDC, polio vaccine campaign securing mpox vaccine for Africa, and donating to reduce food insecurity in mpox affected areas before reviewing the recent statistics on SARS-CoV-2 infection, where to find PEMGARDA, when to use convalescent plasma, a reminder of how and when to use steroids to treat COVID-19, what do when healthcare workers succumb to SARS-CoV-2 infection, if vaccination against SARS-CoV-2 does protect against long COVID, how fibrin drives thromboinflammation and neuropathology in COVID-19, and an evidence based approach to long COVID.

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Links for this episode

Recommendations for seasonal influenza prevention and vaccines (MMWR)
Gaza: poliovirus RNA in sewage water (Reuters)
Success of the polio vaccination campaign in Gaza (Reuters)
UNICEF-Gavi-WO-Africa CDC securing mpox vaccines (Gavi)
mpox vaccine tender (CIDRAP)
What about vaccines? (Bavarian Nordic)
Resolving food insecurity (UNICEF USA)
Semaglutide and the SELECT trial(Journal of the American College of Cardiology)
COVID-19 deaths (CDC)
COVID-19 national and regional trends (CDC)
COVID-19 variant tracker (CDC)
SARS-CoV-2 genomes galore (Nextstrain)
Where to get pemgarda (Pemgarda)
EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
CDC Quarantine guidelines (CDC)
Early phase of SARs-CoV-2 infection (COVID.gov)
NIH COVID-19 treatment guidelines (NIH)
Infectious Disease Society guidelines for treatment and management (ID Society)
Drug interaction checker (University of Liverpool)
Molnupiravir safety and efficacy (JMV)
Convalescent plasma recommendation for immunocompromised (ID Society)
What to do when sick with a respiratory virus (CDC)
When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)
Managing healthcare staffing shortages (CDC)
Optimal duration of systemic corticosteroids treatment (OFID)
Steroids,dexamethasone at the right time (OFID)
Anticoagulation guidelines (hematology.org)
Does vaccination prevent long COVID (LANCET: Respiratory Medicine)
Fibrin drives thromboinflammation & neuropathology in COVID-19(Nature)
Postacute sequelae of COVID: an evidenced based approach, Dr. Daniel Griffin (OFID)
Letters read on TWiV 1146
Dr. Griffin’s COVID treatment summary (pdf)
Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

TWiV 1145: Heartbeats and hoofbeats Sep 01, 2024

TWiV reviews a case of polio in Gaza, more Mpox, COVID-19 boosters, effectiveness of Ebola virus vaccine, measles cases across the US, an endogenous retroviral envelope protein that regulates human cardiomyocyte development, and submergence of an encephalitic alphavirus caused by receptor shifts.

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler

Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email

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Links for this episode

MicrobeTV Discord Server
Gaza baby has polio (Times Israel)
Monkeypox virus clade Ib in Thailand (CIDRAP)
Updated COVID-19 vaccines (FDA)
Effectiveness of Ebola virus vaccine (Lancet Inf Dis)
Measles cases in Georgia, Oregon (CIDRAP)
Retrovirus protein regulates cardiomyocyte development (Cell Stem Cell)
Receptor shifts govern submergence of encephalitis arbovirus (Nature)
Letters read on TWiV 1145
Timestamps by Jolene. Thanks!

Weekly Picks

Kathy – Googlegangers and AWWW clip Rich – RP FLIP (floating instrument platform) Alan – Big labs are bad for careers Vincent – So You’re Underwater: Why Do You See That Circle of Light Above You?

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1144: Clinical update with Dr. Daniel Griffin Aug 31, 2024

In his weekly clinical update, Dr. Griffin discusses Dr. Fauci’s case of West Nile virus, polio vaccine campaign develops in Gaza, disease that associates with Oropouche virus, mpox: vaccines, clinical trial for mpox antiviral and the WHO strategic preparedness and response plan before reviewing the recent statistics on SARS-CoV-2 infection, how to obtain free COVID tests, EUA for updated Novavax COVID vaccine, ISDA support of and where to find PEMGARDA, breakthrough infections when administering PEMGARDA, when to use convalescent plasma, what do when healthcare workers succumb to SARS-CoV-2 infection, if nirmatrelvir/ritonavir is effective at preventing hospitalization of high risk patients, incidence of mental illness in the vaccinated and unvaccinated, the effect of amubarvimab/romlusevimab on long COVID outcome, having an evidence based approach to long COVID and how fibrin drives thromboinflammation and neuropathology in COVID-19.

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Links for this episode

Fauci recovering at home from West Nile Virus infection (STAT News)
Gaza: poliovirus RNA in sewage water (GPEI)
Bombs and polio…..cease fire, Oh my! (Guardian)
The variant type 2 poliovirus in Gaza (United Nations: The Question of Palestine)
25 years polio free? (Facebook)
2 doses of nOPV2= 1.2M vaccines=640,000 children (CNN)
More polio……India, two-year-old child in Tikrikilla, Meghalaya (Business Standard)
Sloth fever……Oropouche virus (USA Today)
Oropouche virus disease import into US (MMWR)
Gabon’s first case of mpox (CIDRAP)
Declaration of mpox (Gabonese Republic Ministry of Health and Social Affairs)
What about vaccines? (Bavarian Nordic)
LC16 replicating smallpox vaccine (WHO)
Historical smallpox vaccination against mpox clade II (Eurosurveillance)
FDA approves Emergent Bio’s smallpox vaccine for mpox (Reuters)
Mpox: epidemiology and vaccinology (Emerging Infectious Disease)
Tecovirimat for MPOX? (STOMP)
UGH! The WHO has a strategic preparedness and response plan to contain mpox outbreak (WHO)
WHO preparedness plan prepares to lunch (CIDRAP)
Working blindly against new mpox isolate (Reuters)
CDC monkey pox response: TRANSMISSION ? (CDC Newsroom)
The mpox (Africa CDC: Centers for Disease Control and Prevention)
Evidence for mpox respiratory transmission(LANCET Microbe)
COVID-19 deaths (CDC)
COVID-19 national and regional trends (CDC)
COVID-19 variant tracker (CDC)
SARS-CoV-2 genomes galore (Nextstrain)
Four free COVID tests! (ASPR: Administration for Strategic Preparedness & Response)
Great, more SARS-CoV-2 testing! (CIDRAP)
EUA for updated Novavax COVID-19 vaccine (FDA)
Infectious Disease Society guidelines for treatment and management (ID Society)
IDSA suggests new preventive COVID-19 agent (IDSA)
Where to get pemgarda (Pemgarda)
EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
Breakthrough from pemivibart/permgarda (bioRxiv)
CDC Quarantine guidelines (CDC)
Early phase of SARs-CoV-2 infection (COVID.gov)
NIH COVID-19 treatment guidelines (NIH)
Infectious Disease Society guidelines for treatment and management (ID Society)
Drug interaction checker (University of Liverpool)
Effectiveness of nirmatrelvir/ritonavir preventing hospitalization of high risk patients (Current Therapeutic Research)
Molnupiravir safety and efficacy (JMV)
Convalescent plasma recommendation for immunocompromised (ID Society)
What to do when sick with a respiratory virus (CDC)
When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)
Managing healthcare staffing shortages (CDC)
Steroids, dexamethasone at the right time (OFID)
Anticoagulation guidelines (hematology.org)
COVID-19, mental illness vaccinated and unvaccinated (JAMA Psychiatry)
Post acute COVID- 19 outcomes amubarvimab/romlusevimab versus placebo (eClinical Medicine)
Postacute sequelae of COVID: an evidenced based approach, Dr. Daniel Griffin (OFID)
Fibrin drives thromboinflammation & neuropathology in COVID-19 (Nature)
Letters read on TWiV 1144
Dr. Griffin’s COVID treatment summary (pdf)
Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

TWiV 1143: SARS-CoV-2 gone wild, with a side of rice Aug 25, 2024

TWiV discusses WHO declaration of Mpox as a public health emergency of international concern, Sweden reports first case of clade 1b outside of Africa, can household pets be productively infected with monkeypox virus, widespread exposure to SARS-CoV-2 in wildlife communities, and modulation of plant defenses by insect salivary GAPDH benefits viral transmission.

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler

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Links for this episode

MicrobeTV Discord Server
Mpox outbreak is PHEIC (WHO)
Tecovirimat not great against monkeypox virus clade I (NIH)
Case of Mpox Clade I in Sweden (PHAS)
Mpox and pets in USA (Emerg Inf Dis)
SARS-CoV-2 widespread in wildlife communities (Nat Comm)
Salivary GAPDH benefits plant virus transmission (Nat Comm)
Letters read on TWiV 1143
Timestamps by Jolene. Thanks!

Weekly Picks

Dickson – NASA Confirms Evidence That Liquid Water Flows on Today’s Mars Kathy – TBP for PCR internal control Rich – xmACIS2 compares the data in the ACIS database to that in GHCN-Daily Alan – Larry, the world’s most highly cited cat Vincent – The Viral Paleontologist Who Unearths Pathogens’ Deep Histories

Listener Pick

Ryan – Mpox emergencies AP News one and two Rona – Up in smoke David – Ode to Joy (YouTube, TikTok)

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1142: Clinical update with Dr. Daniel Griffin Aug 24, 2024

In his weekly clinical update, Dr. Griffin discusses global transmission of mpox, the different clades of the virus and associated pathogenesis, vaccination vs antiviral therapy against mpox and the US’s aid response for controlling the African outbreak before reviewing the recent statistics on SARS-CoV-2 infection, authorization and approval of updated COVID vaccines, the economic benefit of an annual COVID vaccine and if the first updated vaccines against XBB.1.5 were effective, where to find PEMGARDA, breakthrough infections when administering PEMGARDA, when to use convalescent plasma, what do when healthcare workers succumb to SARS-CoV-2 infection, and how long COVID differs in children and adolescents.

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Links for this episode

mpox epidemic caused by monkeypox clade I in affected African countries (European Centre for Disease Prevention and Control)
mpox in Pakistan (Reuters)
mpox imported into Pakistan (UNMC Global Center for Health Security)
mpox domesticated in Taiwan (Focus Taiwan: CAN English News)
clade IIb not Ib in Taiwan (bne Intellinews)
WHO: mpox public health emergency of global care (NY Times)
Vaccines didn’t turn back mpox…..people did (NY Times)
Deadlier mpox version in Thailand (NY Times)
Antiviral tecovirimat….not so much (NIH News)
What about vaccines? (Bavarian Nordic)
Invest or not to invest Barvaian Nordic pox vaccine manufacturer? (Yahoo! Finance)
US to support Africa’s mpox response (CIDRAP)
$35M to support mpox outbreak response in central and eastern Africa (USAID From the AMERICAN PEOPLE)
COVID-19 deaths (CDC)
COVID-19 national and regional trends (CDC)
COVID-19 variant tracker (CDC)
FDA approves and authorizes updated mRNA COVID-19 vaccines (FDA)
Novavax still working on updated COVID-19 vaccine (novavax)
COVID-19 variant update (CDC & IDSA)
Economic benefit of annual COVID-19 vaccination (JID)
Early COVID-19 XBB.1.5 vaccine effectiveness (Influenza and other respiratory viruses)
Uptake of COVID-19 vaccines and associated hospitalization due to COVID-19 in pregnancy (Vaccine)
Novavax heterologous booster demonstrates lower reactogenicity (JID)
Where to get pemgarda (Pemgarda)
EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
Breakthrough from pemivibart/permgarda (bioRxiv)
CDC Quarantine guidelines (CDC)
Early phase of SARs-CoV-2 infection (COVID.gov)
NIH COVID-19 treatment guidelines (NIH)
Infectious Disease Society guidelines for treatment and management (ID Society)
Drug interaction checker (University of Liverpool)
Molnupiravir safety and efficacy (JMV)
Convalescent plasma recommendation for immunocompromised (ID Society)
What to do when sick with a respiratory virus (CDC)
When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)
Managing healthcare staffing shortages (CDC)
Steroids,dexamethasone at the right time (OFID)
Anticoagulation guidelines (hematology.org)
Long COVID differs in children and adolescents (JAMA Network)
Letters read on TWiV 1142
Dr. Griffin’s COVID treatment summary (pdf)
Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

TWiV 1141: Being green with the Red Queen Aug 18, 2024

TWiV discusses the spread of monkeypox virus clade 1b in Africa, COVID drops to tenth leading cause of death in the US, response to detection of poliovirus in Gaza, mechanism of MIS-C after SARS-CoV-2 infection, neonatal Fc receptor is a pan-arterivirus receptor, and antiviral immunity in plants mediated by protein arginine methyltransferase 6.

Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Brianne Barker

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Links for this episode

MicrobeTV Discord Server
Mpox widespread in Africa (CIDRAP)
Africa declares Mpox emergency (Science)
COVID drops to 10th leading cause of US deaths (MMWR)
Response to detection of poliovirus in Gaza (WHO)
Molecular mimicry in MIS-C (Nature)
Neonatal Fc receptor is pan-arterivirus receptor (Nat Comm)
Antiviral immunity in plants by protein arginine methytransferase 6 (Cell Host Micr)
Letters read on TWiV 1141
Timestamps by Jolene. Thanks!

Weekly Picks

Brianne – Kate Douglass: Olympian and Statistician (Swimming in Data) Dickson – Women of recent note: Kamala Harris (Democratic Party presidential candidate); Katie Ladecky (10,000 meters); Sydney McLaughlin-Levrone (400 meter hurdles); Gabby Thomas, Sha’Carri Richardson, Melissa Jefferson, and Twanisha Terry (4 x 100 relay); women’s basketball team Rich – Texas State University Forensic Anthropology Research Facility Vincent – Sea lion ‘camera crews’ capture new footage of ocean floor

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1140: Clinical update with Dr. Daniel Griffin Aug 17, 2024

In his weekly clinical update, Dr. Griffin discusses the harms of perpetuating the lab leak hypothesis and the recent ACIP recommendations for the RSV vaccine for those individuals over 60, before reviewing the recent statistics on SARS-CoV-2 infection, treatment guidelines for the different phases of COVID, including vaccines, Pemgarda, early treatment with Paxlovid, remdesivir and molnupiravir, steroids at the right time, anticoagulation support, immune modulation in some cases, and a comprehensive definition of long COVID.

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Links for this episode

Measles transmission after secondary vaccination failure (Emerg Inf Dis)
Mpox public health emergency of international concern (WHO)
First case of new mpox strain outside of Africa (Reuters)
COVID-19 national trend (CDC)
COVID-19 deaths (CDC)
Where to get pemgarda (Pemgarda
CDC Quarantine guidelines (CDC)
Early phase of SARs-CoV-2 infection (COVID.gov)
Individual monoclonal antibodies against SARS-CoV-2 should be used (CID)
NIH COVID-19 treatment guidelines (NIH)
Infectious Disease Society guidelines for treatment and management (ID Society)
Drug interaction checker (University of Liverpool)
Molnupiravir safety and efficacy (JMV)
Convalescent plasma recommendation for immunocompromised (ID Society)
Managing healthcare staffing shortages (CDC)
Steroids,dexamethasone at the right time (OFID)
Anticoagulation guidelines (hematology.org)
Long COVID science, research and policy (Nature Medicine)
Measurements of prior SARS-CoV-2 infection and postacute sequelae by the clinical laboratory (Annals of Internal Medicine)
Risk factors for long COVID syndrome in postmenopausal women with previous SARS-CoV-2 infections (Annals of Epidemiology)
New studies estimate long-COVID rates, identify risk factors (CIDRAP)
Monitoring long COVID via telemedicine (PLoS One)
Letters read on TWiV 1140
Dr. Griffin’s COVID treatment summary (pdf)
Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

TWiV 1139: Long COVID with Dr. Judith Bruchfeld Aug 11, 2024

Vincent travels to the Karolinska Institute in Stockholm on 31 May 2024 to meet with Dr. Judith Bruchfeld and discuss her research on the etiology and treatment of Long COVID.

Hosts: Vincent Racaniello

Guest: Judith Bruchfeld

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Links for this episode

MicrobeTV Discord Server
Immune system perturbations in Long COVID (J Immunol)
Post-COVID immune system perturbations (J Immunol)
Systems disregulation in Long COVID (Sci Rep)
Clincal standards for diagnosing, treating, and preventing Long COVID (Intl J Tuberc Lung Dis)
Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1138: Clinical update with Dr. Daniel Griffin Aug 10, 2024

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Links for this episode

Harms of the lab leak hypothesis (Journal of Virology)
Lab leak mania (PaulOffit, Substack)
This is a special message: pandemic started in nature! (TWiV)
RSV vaccine recommendations August 6 2024 (MMWR)
COVID-19 national trend (CDC)
COVID-19 deaths (CDC)
Where to get Pemgarda (Pemgarda)
CDC Quarantine guidelines (CDC)
Early phase of SARs-CoV-2 infection (COVID.gov)
NIH COVID-19 treatment guidelines (NIH)
Infectious Disease Society guidelines for treatment and management (ID Society)
Drug interaction checker (University of Liverpool)
Molnupiravir safety and efficacy (JMV)
Convalescent plasma recommendation for immunocompromised (ID Society)
Managing healthcare staffing shortages (CDC)
Steroids,dexamethasone at the right time (OFID)
Anticoagulation guidelines (hematology.org) Long COVID defined (NEJM)
Contribute to our Floating Doctors fundraiser
Lenacapavir on Puscast #60
Letters read on TWiV 1138
Dr. Griffin’s COVID treatment summary (pdf)
Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

TWiV 1137: Dengue is not BANAL Aug 04, 2024

TWiV discusses a twice-yearly antiviral for prevention of AIDS, the WHO pandemic plan, West Nile resurgence in the US, the BANAL SARS-CoV-2 related viruses reproduce in human cells but do not transmit among animal hosts, and an amino acid change in dengue virus that enhances midgut replication in mosquitoes but reduces pathogenicity in humans.

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler

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Links for this episode

MicrobeTV Discord Server
PrEP with HIV-1 capsid inhibitor (NEJM)
WHO pandemic plan (pdf)
West Nile virus resurgence in US (NY Times)
Properties of BANAL SARS-CoV-2 like viruses (Nat Micro)
BANAL viruses on TWiV 809
Different effect of dengue virus amino acid change in humans and mosquitoes (Sci Transl Med)
Eng Ong Ooi on TWiV 633
Letters read on TWiV 1137
Timestamps by Jolene. Thanks!

Weekly Picks

Kathy – Using big data to improve traffic light timing Rich – Dillo Dirt Alan – Dueling Banjos on banjo and kora Vincent – The world’s most expensive dinosaur and more

Listener Pick

Mike – Science through a glass darkly Lisa – On A Mission“ Season Four

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1136: Clinical update with Dr. Daniel Griffin Aug 03, 2024

In his weekly clinical update, Dr. Griffin discusses how the pandemic may have effected our trust in physicians and hospitals and if waiting longer to make strain selection for the seasonal influenza vaccine would be advantageous before reviewing the recent statistics on SARS-CoV-2 infection, how different CVODI-19 vaccines effect the cardiovascular system, if the a third of either COVID-19 mRNA vaccine is effective, where to find PEMGARDA, if convalescent plasma, what do when healthcare workers succumb to SARS-CoV-2 infection, and the long term consequences of a SARS-CoV-2 infection on human health including incidences of diabetes, respiratory problems, hearing loss and maternal-fetal health.

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Links for this episode

In physicians and hospitals, we trust (JAMA Network)
Are there benefits for delaying seasonal influenza vaccine selections (JID)
Personal protective effect for wearing surgical face masks in public spaces (the BMJ)
COVID-19 national trend (CDC)
COVID-19 deaths (CDC)
Cardiovascular safety of different COVID-19 vaccination(Nature Comm)
Effectiveness of a third dose of mRNA-1273 versus BNT162b2 among older adults (Vaccine)
Where to get pemgarda (Pemgarda)
CDC Quarantine guidelines (CDC)
Early phase of SARs-CoV-2 infection (COVID.gov)
NIH COVID-19 treatment guidelines (NIH)
Infectious Disease Society guidelines for treatment and management (ID Society)
Drug interaction checker (University of Liverpool)
Molnupiravir safety and efficacy (JMV)
Convalescent plasma recommendation for immunocompromised (ID Society)
Managing healthcare staffing shortages (CDC)
Steroids,dexamethasone at the right time (OFID)
Anticoagulation guidelines (hematology.org)
Incidence of diabetes after SARS-CoV-2 infection (The Lancet Diabetes & Endocrinology)
Post-COVID-19 respiratory sequelae two years after hospitalization (The Lancet Regional Health)
Incidence of hearing loss following COVID-19 among young adults (eClinical Medicine)
The effect of long-term COVID-19 infection on maternal and fetal complications (Scientific Reports)
Contribute to our Floating Doctors fundraiser
Letters read on TWiV 1136
Dr. Griffin’s COVID treatment summary (pdf)
Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

TWiV 1135: Resistance is not always futile Jul 28, 2024

TWiV reviews whats going on with measles and its global resurgence, poliovirus found in Gaza, vaccine hesitancy in a community, 14 year old dies of Nipah, selection of SARS-CoV-2 viruses resistant to nirmatrelvir, and protective but non-neutralizing antibodies from survivors of Crimean-Congo hemorrhagic fever virus.

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Brianne Barker, and Angela Mingarelli

Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email

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Links for this episode

MicrobeTV Discord Server
What’s going on with measles? (J Virol)
Poliovirus in Gaza (Science)
Sanitation concerns in Gaza (AP)
Community vaccine beliefs (PLoS One)
14 year old dies of Nipah in India (Hindustan Times)
Selection of nirmatrelvir resistance mutants (Sci Adv)
CCHFV monoclonal antibodies (Cell Rep)
CCHFV vaccine (TWiV 565)
Prometheus Project (TWiV 578)
TWiV at USAMRIID (TWiV 1015)
Letters read on TWiV 1135
Timestamps by Jolene. Thanks!

Weekly Picks

Angela – Animal research is not always king Brianne – Why the US has more tornadoes than any other country Dickson – Earth’s core has slowed so much it’s moving backward Alan – Article about the Smithsonian’s forensic ornithology lab, led by Carla Dove Vincent – Seventh patient ‘cured’ of HIV: why scientists are excited

Listener Pick

Charles – An Inquiry into Morals by Robert M. Pirsig and My Beloved Monster by Caleb Carr

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1134: Clinical update with Dr. Daniel Griffin Jul 27, 2024

In his weekly clinical update, Dr. Griffin discusses Merck’s RSV preventative monoclonal antibody Clesrovimab before reviewing the recent statistics on SARS-CoV-2 infection, if previous SARS-COV-2 infections predict the outcome of subsequent infections, if using COVID rapid diagnostic tests is cost effective, if the protein based vaccine NVX-CoV2327 elicits a durable immune response, if combination treatment of vaccine and antiviral drugs effectively protect against hospitalization, where to find PEMGARDA, what do when healthcare workers succumb to SARS-CoV-2 infection, and how COVID-19 may alter the cognitive trajectories of older patients.

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Links for this episode

Clesrovimab, RSV preventative monoclonal antibody for infants (Merck)
COVID-19 national trend (CDC)
COVID-19 deaths (CDC)
Characterizing SARS-CoV-2 reinfections and long COVID (Communications Medicine)
Cost-effectiveness of COVID rapid diagnostic tests (PLoS Medicine)
NVX-CoV2373 against pre-Delta and Delta strains of COVID-19 little evidence of waning immune response (CID)
Combined Protection of Vaccination and Nirmatrelvir-Ritonavir Against Hospitalization(CID)
Pemgarda infusion center locator (Pemgarda)
Respiratory virus guidance (CDC)
Early phase of SARS-CoV-2 infection (COVID.gov)
NIH COVID-19 treatment guidelines (NIH)
Infectious Disease Society guidelines for treatment and management (ID Society)
Drug interaction checker (University of Liverpool)
Molnupiravir safety and efficacy (JMV)
Convalescent plasma recommendation for immunocompromised (ID Society)
What do when your heathcare provider is infected with SARS-CoV-2 (CDC)
Managing healthcare staffing shortages (CDC)
Steroids,dexamethasone at the right time (OFID)
Anticoagulation guidelines (hematology.org)
Cognitive trajectories in older survivors of COVID-19 up to 2.5 years post-infection(Nature Aging)
Contribute to our Floating Doctors fundraiser
Letters read on TWiV 1134
Dr. Griffin’s COVID treatment summary (pdf)
Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

TWiV 1133: Gain of function makes us safer Jul 21, 2024

TWiV reviews cases of measles in Brooklyn NY and Washington DC, stalling of global childhood vaccination, licenses H5N1 vaccines protect against circulating strains, viruses traveling without passports. OC43 SARS-CoV- 2 spike replacement virus as an improved BSL-2 proxy virus for SARS-CoV-2 neutralization assays, and deep mutational scanning reveals functional constraints and antibody-escape potential of Lassa virus glycoprotein complex.

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler

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Become a patron of TWiV!

Links for this episode

MicrobeTV Discord Server
Measles in Brooklyn NY (ABC)
Measles in Washington DC (DC Health)
Global childhood immunization stalls (WHO)
Licensed H5N1 vaccines protect against circulating strains (Nat Med)
Viruses moving without passports (European CDC)
OC42-SARS-CoV-2 replacement spike virus (PNAS)
Deep mutational scanning of Lassa virus glycoprotein (Immunity)
Letters read on TWiV 1133
Timestamps by Jolene. Thanks!

Weekly Picks

Dickson – Elemental sulfur found on Mars Kathy – Lennette Lectures at ASV, including Gail Wertz, ASV 2024 Rich – Electricity maps (Opinions: Nuclear Waste Is Misunderstood; Should We Be Worried About Nuclear Waste?) Alan – Nature sent an investigative reporter to a predatory conference Vincent – Coal-filled trains are likely sending people to the hospital

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV 1132: Clinical update with Dr. Daniel Griffin Jul 20, 2024

In his weekly clinical update, Dr, Daniel Griffin reviews President Biden’s case of COVID, reviews recent statistics on SARS-CoV-2 infection, discusses post-acute sequelae after infection during pregnancy, the use of nirmatrelvir-ritonavir for post-exposure prophylaxis, where to find Pemgarda, effectiveness of combined nirmatrelvir-ritonavir-molnupiravir treatment, effectiveness of Ensitrelvir in reducing severe outcomes in outpatients at high risk for COVID-19, effectiveness of combined nirmatrelvir-ritonavir-molnupiravir treatment in patients hospitalized with COVID-19, CDC update of Long COVID Basics page, postacute sequelae of SARS-CoV-2 infection in the pre-delta, delta, and omicron eras, Long COVID risk has dropped over time but remains substantial, efficacy of antivirals, corticosteroids, and mAbs as acute COVID treatments in reducing the incidence of long COVID, and the interplay between diet and the gut microbiome: implications for health and disease.

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Become a patron of TWiV!

Links for this episode

President Biden has COVID (CNN, USA Today)
COVID-19 national trend (CDC)
COVID-19 deaths (CDC)
Post–acute sequelae of COVID after infection during pregnancy (OB & Gyn)
Oral nirmatrelvir–ritonavir as postexposure prophylaxis for Covid-19 (NEJM)
Pemgarda infusion center locator (Pemgarda)
Unable to access pemgarda, gotta call Daniel (microbeTV)
CDC Quarantine guidelines (CDC)
Early phase of SARs-CoV-2 infection (COVID.gov)
NIH COVID-19 treatment guidelines (NIH)
Infectious Disease Society guidelines for treatment and management (ID Society)
Drug interaction checker (University of Liverpool)
Combined treatment of COVID reduces molnupiravir-induced mutagenicity (J Inf Dis)
Effectiveness of ensitrelvir in reducing severe outcomes in outpatients at high risk for COVID-19 (Inf Dis Therapy)
Comparative effectiveness of combination therapy with nirmatrelvir–ritonavir and remdesivir versus monotherapy (Lancet)
Molnupiravir safety and efficacy (JMV)
Convalescent plasma recommendation for immunocompromised (ID Society)
Isolation guidance (CDC)
Managing healthcare staffing shortages (CDC)
Steroids, dexamethasone at the right time (OFID)
Anticoagulation guidelines (hematology.org)
Long COVID is defined (National Academies)
Long COVID: the ANSWERS! (longcovidtheanswers.com)
The FACTS: post COVID-19=long COVID? (WHO)
The BASICS of long COVID-19 (CDC)
Postacute sequelae of SARS-CoV-2 infection in the pre-delta, delta, and omicron eras (NEJM)
Long Covid risk has dropped over time but remains substantial (CNN)
Efficacy of antivirals, corticosteroids, and mAbs as acute COVID treatments in reducing the incidence of long COVID (Clin Micro Inf)
Diet and the gut microbiome: implications for health and disease (Nat Rev Micro)
Contribute to our Floating Doctors fundraiser
Letters read on TWiV 1132
Dr. Griffin’s COVID treatment summary (pdf)
Timestamps by Jolene. Thanks!